Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt20e05
(693 letters)
Database: spombe
5004 sequences; 2,362,478 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SPAC3A12.14 |cam1||calmodulin Cam1 |Schizosaccharomyces pombe|ch... 97 2e-21
SPCC1682.04 |cdc31||centrin|Schizosaccharomyces pombe|chr 3|||Ma... 71 2e-13
SPAC29A4.05 |cam2||myosin I light chain Cam2|Schizosaccharomyces... 69 6e-13
SPAP8A3.08 |cdc4||myosin II light chain|Schizosaccharomyces pomb... 53 5e-08
SPCC830.06 |||calcineurin regulatory subunit |Schizosaccharomyce... 49 7e-07
SPAC926.03 |rlc1||myosin II regulatory light chain |Schizosaccha... 42 1e-04
SPAC18B11.04 |ncs1||related to neuronal calcium sensor Ncs1|Schi... 41 2e-04
SPAC1687.14c |||EF hand family protein, unknown role|Schizosacch... 37 0.002
SPBC11G11.02c |end3||actin cortical patch component End3 |Schizo... 31 0.12
SPBC83.01 |ucp8||UBA/EH/EF hand domain protein Ucp8|Schizosaccha... 31 0.12
SPAC25B8.09 |||trans-aconitate 3-methyltransferase |Schizosaccha... 29 0.84
SPAC26H5.05 |||IPT/TIG ankyrin repeat protein|Schizosaccharomyce... 27 2.6
SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 27 3.4
SPCC188.07 |ccq1||telomere maintenence protein|Schizosaccharomyc... 27 3.4
SPBP19A11.04c |mor2|cps12|morphogenesis protein Mor2|Schizosacch... 27 3.4
SPAC22F8.11 |plc1||phosphoinositide phospholipase C Plc1|Schizos... 26 4.5
SPAC17A5.12 |ucp7||UBA/TPR/DNAJ domain protein Ucp7|Schizosaccha... 26 4.5
SPCC550.11 |||karyopherin|Schizosaccharomyces pombe|chr 3|||Manual 26 5.9
SPAC1006.06 |rgf2||RhoGEF Rgf2|Schizosaccharomyces pombe|chr 1||... 25 7.9
SPBC4F6.07c |||ATP-dependent RNA helicase Mak5 |Schizosaccharomy... 25 7.9
>SPAC3A12.14 |cam1||calmodulin Cam1 |Schizosaccharomyces pombe|chr
1|||Manual
Length = 150
Score = 97.1 bits (231), Expect = 2e-21
Identities = 53/150 (35%), Positives = 84/150 (56%)
Frame = +2
Query: 92 VSDLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDF 271
+++ R AF L DRD DG++T EL ++R+LG + + D+I + GNG ID +F
Sbjct: 11 IAEFREAFSLFDRDQDGNITSNELGVVMRSLGQSPTAAELQDMINEVDADGNGTIDFTEF 70
Query: 272 MQWVTKIQALQGLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEP 451
+ + + D+EEE+ AFKVFD+D NGYIT +EL L +GE
Sbjct: 71 LTMMAR---------KMKDTDNEEEVRE----AFKVFDKDGNGYITVEELTHVLTSLGER 117
Query: 452 VTDAQLNQVLALGDIDHDGRIDYEEFVKML 541
++ ++ ++ D D DG I+YEEF +++
Sbjct: 118 LSQEEVADMIREADTDGDGVINYEEFSRVI 147
Score = 51.6 bits (118), Expect = 1e-07
Identities = 25/69 (36%), Positives = 42/69 (60%)
Frame = +2
Query: 335 SEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLALGDIDHDGRI 514
++E+I + AF +FDRD +G IT +EL + +G+ T A+L ++ D D +G I
Sbjct: 7 TDEQIA-EFREAFSLFDRDQDGNITSNELGVVMRSLGQSPTAAELQDMINEVDADGNGTI 65
Query: 515 DYEEFVKML 541
D+ EF+ M+
Sbjct: 66 DFTEFLTMM 74
Score = 50.4 bits (115), Expect = 2e-07
Identities = 20/63 (31%), Positives = 43/63 (68%)
Frame = +2
Query: 98 DLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDFMQ 277
++R AF + D+D +G++T EL +L +LG +S + ++D+I++A G+G+I+ +F +
Sbjct: 86 EVREAFKVFDKDGNGYITVEELTHVLTSLGERLSQEEVADMIREADTDGDGVINYEEFSR 145
Query: 278 WVT 286
++
Sbjct: 146 VIS 148
>SPCC1682.04 |cdc31||centrin|Schizosaccharomyces pombe|chr
3|||Manual
Length = 176
Score = 70.5 bits (165), Expect = 2e-13
Identities = 43/149 (28%), Positives = 75/149 (50%)
Frame = +2
Query: 98 DLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDFMQ 277
D+ AF L D D D + EL+ +R LG + +++D KTG G + DF++
Sbjct: 38 DINEAFKLFDSDKDNAIDYHELRAAMRALGFNAEKSEVLKILRDFDKTGKGYLQMEDFVR 97
Query: 278 WVTKIQALQGLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVT 457
+T+ + D EEI R AF++FD D+ G I+ L+ + + E +
Sbjct: 98 VMTEKIVER---------DPLEEIKR----AFELFDDDETGKISLRNLRRVAKELNENID 144
Query: 458 DAQLNQVLALGDIDHDGRIDYEEFVKMLL 544
D +L ++ D+D DG I+ +EF+ +++
Sbjct: 145 DQELEAMIEEFDLDQDGEINEQEFIAIMM 173
Score = 39.9 bits (89), Expect = 3e-04
Identities = 21/67 (31%), Positives = 38/67 (56%)
Frame = +2
Query: 341 EEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLALGDIDHDGRIDY 520
EE +D+ AFK+FD D + I EL+AA+ +G +++ ++L D G +
Sbjct: 33 EEQRQDINEAFKLFDSDKDNAIDYHELRAAMRALGFNAEKSEVLKILRDFDKTGKGYLQM 92
Query: 521 EEFVKML 541
E+FV+++
Sbjct: 93 EDFVRVM 99
>SPAC29A4.05 |cam2||myosin I light chain Cam2|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 143
Score = 68.9 bits (161), Expect = 6e-13
Identities = 47/149 (31%), Positives = 85/149 (57%)
Frame = +2
Query: 98 DLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDFMQ 277
+++ AF L D D DG + + + +LR+LGI V+D ++L K +++ G+ IDE FM
Sbjct: 10 EMKEAFVLYDIDKDGLIPTSHVGSVLRSLGINVTD---AELAKLSNELGDA-IDEKKFMS 65
Query: 278 WVTKIQALQGLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVT 457
+V+ L T +SEEE + AF+VFD+D++GYI + ++ +GE ++
Sbjct: 66 FVSN-----KLRET----ESEEEYIK----AFRVFDKDNSGYIETAKFADYMKTLGEKLS 112
Query: 458 DAQLNQVLALGDIDHDGRIDYEEFVKMLL 544
D ++ ++ D + G DY +FV+ ++
Sbjct: 113 DNEVQLMVQEADPTNSGSFDYYDFVQRIM 141
>SPAP8A3.08 |cdc4||myosin II light chain|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 141
Score = 52.8 bits (121), Expect = 5e-08
Identities = 41/150 (27%), Positives = 73/150 (48%)
Frame = +2
Query: 95 SDLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDFM 274
S + AF L DR G + + +LR G + + + ++ + L E D
Sbjct: 6 SPYKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPT-------LAEITEIESTLPAEVDME 58
Query: 275 QWVTKIQALQGLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPV 454
Q++ + G D+ GD EE + F+VFD+D G I EL+ L +GE +
Sbjct: 59 QFLQVLNRPNGFDMP---GDPEE-----FVKGFQVFDKDATGMIGVGELRYVLTSLGEKL 110
Query: 455 TDAQLNQVLALGDIDHDGRIDYEEFVKMLL 544
++ +++++L G DG ++Y +FV+M+L
Sbjct: 111 SNEEMDELLK-GVPVKDGMVNYHDFVQMIL 139
>SPCC830.06 |||calcineurin regulatory subunit |Schizosaccharomyces
pombe|chr 3|||Manual
Length = 174
Score = 48.8 bits (111), Expect = 7e-07
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Frame = +2
Query: 92 VSDLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDF 271
+ +R F +D + G + E F+ ++ S+ L S L + G G +D +F
Sbjct: 23 IERIRKRFIKIDANQSGSIDRNE--FL--SIPSVASNPLASRLFSVVDEDGGGDVDFQEF 78
Query: 272 MQWVTKIQALQGLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALE-MIGE 448
+ L V + G+ EE+ L AFK++D D +GYI+ EL L+ M+G
Sbjct: 79 ---------INSLSVFSVHGNKEEK----LKFAFKIYDIDRDGYISNGELYLVLKMMVGT 125
Query: 449 PVTDAQLNQV----LALGDIDHDGRIDYEEF 529
+ + QL Q+ + D D DG+I +EEF
Sbjct: 126 NLREDQLQQIVDKTIMEVDKDRDGKISFEEF 156
Score = 31.9 bits (69), Expect = 0.090
Identities = 20/77 (25%), Positives = 39/77 (50%)
Frame = +2
Query: 311 DVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLALG 490
D+ ++ S EEI R + F D + +G I R+E + + P+ +++ ++
Sbjct: 11 DLISNSSFSNEEIER-IRKRFIKIDANQSGSIDRNEFLSIPSVASNPLA----SRLFSVV 65
Query: 491 DIDHDGRIDYEEFVKML 541
D D G +D++EF+ L
Sbjct: 66 DEDGGGDVDFQEFINSL 82
>SPAC926.03 |rlc1||myosin II regulatory light chain
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 184
Score = 41.5 bits (93), Expect = 1e-04
Identities = 36/147 (24%), Positives = 65/147 (44%)
Frame = +2
Query: 92 VSDLRTAFGLLDRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDENDF 271
+ +L+ AF LLD+D DG++ +++ ML +L + S+D I+ + + N
Sbjct: 47 IQELKEAFALLDKDGDGNIGREDVKTMLTSLNQDASEDSINHMFESI----------NPP 96
Query: 272 MQWVTKIQALQGLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEP 451
+ + A+ + S DLL AF FD +G I ++ AL +G+
Sbjct: 97 INLAAFLTAMGSMLCRISP-------RNDLLEAFSTFDDTQSGKIPISTMRDALSSMGDR 149
Query: 452 VTDAQLNQVLALGDIDHDGRIDYEEFV 532
+ ++ +L G YE+FV
Sbjct: 150 MDPQEVESILR--SYTSHGVFYYEKFV 174
>SPAC18B11.04 |ncs1||related to neuronal calcium sensor
Ncs1|Schizosaccharomyces pombe|chr 1|||Manual
Length = 190
Score = 40.7 bits (91), Expect = 2e-04
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +2
Query: 371 FKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLALGDIDHDGRIDYEEFVKML 541
F VFD D NGYI E AL + + +L L D+D++G I Y+E ++++
Sbjct: 69 FNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIV 125
Score = 37.1 bits (82), Expect = 0.002
Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 12/77 (15%)
Frame = +2
Query: 335 SEEEITRDLLAAFKVFDRDDNGYITRDEL----QAALEMIG--------EPVTDAQLNQV 478
S E+ L+ AF+++D D+NG I+ DE+ A +M+G E + ++N++
Sbjct: 93 SRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKI 152
Query: 479 LALGDIDHDGRIDYEEF 529
+ D + DG++ EEF
Sbjct: 153 FNMMDKNKDGQLTLEEF 169
>SPAC1687.14c |||EF hand family protein, unknown
role|Schizosaccharomyces pombe|chr 1|||Manual
Length = 76
Score = 37.1 bits (82), Expect = 0.002
Identities = 20/65 (30%), Positives = 35/65 (53%)
Frame = +2
Query: 344 EITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLALGDIDHDGRIDYE 523
E+ + AF +FD GYI ++L+ + +GE +T QL +L L +G++ E
Sbjct: 9 EMDEEAEEAFDLFDVTHKGYIDFEDLRRSCAQLGENLTKEQLQLMLDLAGT--NGKVSRE 66
Query: 524 EFVKM 538
EF ++
Sbjct: 67 EFAEL 71
>SPBC11G11.02c |end3||actin cortical patch component End3
|Schizosaccharomyces pombe|chr 2|||Manual
Length = 375
Score = 31.5 bits (68), Expect = 0.12
Identities = 14/46 (30%), Positives = 25/46 (54%)
Frame = +2
Query: 392 DNGYITRDELQAALEMIGEPVTDAQLNQVLALGDIDHDGRIDYEEF 529
+NGY++ + L ++ +L ++ L DID DG D++EF
Sbjct: 19 ENGYLSGSKAAGVLR--SSKLSSDKLEKIWDLADIDDDGMFDFDEF 62
>SPBC83.01 |ucp8||UBA/EH/EF hand domain protein
Ucp8|Schizosaccharomyces pombe|chr 2|||Manual
Length = 884
Score = 31.5 bits (68), Expect = 0.12
Identities = 15/48 (31%), Positives = 24/48 (50%)
Frame = +2
Query: 350 TRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLALGD 493
+ +L + D D GYI +DE A+E+I ++ L +LA D
Sbjct: 335 SEELARIWDTVDTQDRGYIDKDEFAVAMEIIKLRLSGKSLASILAYDD 382
>SPAC25B8.09 |||trans-aconitate 3-methyltransferase
|Schizosaccharomyces pombe|chr 1|||Manual
Length = 251
Score = 28.7 bits (61), Expect = 0.84
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -1
Query: 273 MKSFSSIKPLPVLLASLMRSEMRSSLTSMPRLRN 172
M SFSSI LPV M +E+ + ++PR +N
Sbjct: 197 MNSFSSINRLPVEEKEKMHAELDEIIKTIPRAQN 230
>SPAC26H5.05 |||IPT/TIG ankyrin repeat protein|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 1151
Score = 27.1 bits (57), Expect = 2.6
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Frame = -1
Query: 351 VISSSESPPLVVTSKPCKACIFVTHCMKSFSSIKPLPVLLASLMRSEMRSSLTSMPRLRN 172
V+S S + P +VT P ++ + SS + L L S+ S S L++
Sbjct: 475 VLSKSNTVPNLVTGFPTRSDNPPNEKRRRTSSSENSRALDIQLSASDSHSP-NSKSTLKS 533
Query: 171 MNCSSAGVT*-PSLSRSNSPNAVRRSDTKNSFLITRV 64
+ S+ ++ PS+ +P+ V S +KN F + RV
Sbjct: 534 VEGSAFSMSKSPSVLSMTTPSGVSPSISKNGFHVVRV 570
>SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase
Ppk38|Schizosaccharomyces pombe|chr 3|||Manual
Length = 650
Score = 26.6 bits (56), Expect = 3.4
Identities = 17/48 (35%), Positives = 25/48 (52%)
Frame = -1
Query: 270 KSFSSIKPLPVLLASLMRSEMRSSLTSMPRLRNMNCSSAGVT*PSLSR 127
+S SS+ P P M S M ++ SMP L N + ++ G T +SR
Sbjct: 346 QSKSSVFPQPASAMKPMASPMLPNVNSMPYLSNGDHNNNGNTSSPVSR 393
>SPCC188.07 |ccq1||telomere maintenence protein|Schizosaccharomyces
pombe|chr 3|||Manual
Length = 735
Score = 26.6 bits (56), Expect = 3.4
Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = -1
Query: 270 KSFSSIKPLPVL--LASLMRSEMRSSLTSMPRLRNMNCSSAGVT*PSLSRSNSPNAVRRS 97
++FSS PLP L LASL +E R S S+ ++ + S+ T PS SP+ + S
Sbjct: 419 ENFSSW-PLPPLMDLASLSVAEPRDSQPSVSQVNDTFVKSSDSTFPSSQSMQSPSKL-HS 476
Query: 96 DTKNS 82
T N+
Sbjct: 477 LTSNA 481
>SPBP19A11.04c |mor2|cps12|morphogenesis protein
Mor2|Schizosaccharomyces pombe|chr 2|||Manual
Length = 2196
Score = 26.6 bits (56), Expect = 3.4
Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Frame = -1
Query: 381 NTLNAASRSLVISSSESP-----PLVVTS-KPCK-ACIFVTHCMKSFSSIKPLPVLLASL 223
N L ++ I+S+ES PL+ T P + A +F C+ ++ P L+ SL
Sbjct: 871 NHLRGLQETIKITSAESLFSMVLPLIFTEFSPIREAVVFAIGCI----NVNAFPQLVRSL 926
Query: 222 MRSEMRSSLTSMPRLRNMNCSSAGVT*PSLSRSNSPNAVRRSDTKNSFLIT 70
S+ + + AG+ PS+ R N P+ + RS+ + F +T
Sbjct: 927 ------KPYISVLKQDHQEFIFAGLNFPSVKRRNKPDLLLRSEIAHIFAMT 971
>SPAC22F8.11 |plc1||phosphoinositide phospholipase C
Plc1|Schizosaccharomyces pombe|chr 1|||Manual
Length = 899
Score = 26.2 bits (55), Expect = 4.5
Identities = 13/75 (17%), Positives = 35/75 (46%)
Frame = +2
Query: 305 GLDVTTSGGDSEEEITRDLLAAFKVFDRDDNGYITRDELQAALEMIGEPVTDAQLNQVLA 484
GL++ G+ + + +L ++ +++ + + ++ +M+ + L +
Sbjct: 282 GLNLVCHQGEKMIDYSENL-NPWEKLEKEQSAQLDLGDVHRMCQMLHLNASMEFLEETFQ 340
Query: 485 LGDIDHDGRIDYEEF 529
D DH G++ +EEF
Sbjct: 341 KADADHSGKLSFEEF 355
>SPAC17A5.12 |ucp7||UBA/TPR/DNAJ domain protein
Ucp7|Schizosaccharomyces pombe|chr 1|||Manual
Length = 697
Score = 26.2 bits (55), Expect = 4.5
Identities = 10/29 (34%), Positives = 18/29 (62%)
Frame = +2
Query: 191 EVSDDLISDLIKDASKTGNGLIDENDFMQ 277
E ++++S L+++ TGN L + DF Q
Sbjct: 402 ETLNNMVSALVEEQQSTGNELFRKGDFSQ 430
>SPCC550.11 |||karyopherin|Schizosaccharomyces pombe|chr 3|||Manual
Length = 1029
Score = 25.8 bits (54), Expect = 5.9
Identities = 14/47 (29%), Positives = 25/47 (53%)
Frame = +2
Query: 125 DRDSDGHVTPAELQFMLRNLGIEVSDDLISDLIKDASKTGNGLIDEN 265
+ D D V +++ +LG E+S D++ D + GN L+DE+
Sbjct: 919 EADDDEGVDDFAVEYGGPDLGGEISADVVDDFDEFEHFQGNYLLDED 965
>SPAC1006.06 |rgf2||RhoGEF Rgf2|Schizosaccharomyces pombe|chr
1|||Manual
Length = 1158
Score = 25.4 bits (53), Expect = 7.9
Identities = 19/48 (39%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = -1
Query: 255 IKPLPVLLASLMRSEMRSSLTSMPRLRNMNCSSAGVT*P-SLSRSNSP 115
++PLP+ L S+ E S S+PR SSA +T P S+++SN P
Sbjct: 719 LRPLPLELLSISYIEDSPSRGSLPR----RPSSALLTNPISITKSNPP 762
>SPBC4F6.07c |||ATP-dependent RNA helicase Mak5 |Schizosaccharomyces
pombe|chr 2|||Manual
Length = 648
Score = 25.4 bits (53), Expect = 7.9
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +2
Query: 137 DGHVTPAE--LQFMLRNLGIEVSDDLISDLIKDASKTGN 247
DG V E L+ M + LG+E SDD DL K + + N
Sbjct: 545 DGRVGREEAWLKSMAQELGVESSDDEDPDLPKKSESSKN 583
Database: spombe
Posted date: Oct 4, 2007 10:57 AM
Number of letters in database: 2,362,478
Number of sequences in database: 5004
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 2,606,800
Number of Sequences: 5004
Number of extensions: 48908
Number of successful extensions: 185
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 178
length of database: 2,362,478
effective HSP length: 70
effective length of database: 2,012,198
effective search space used: 321951680
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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