Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt20c03
(789 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 148 2e-35
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 148 2e-35
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 148 2e-35
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 142 1e-33
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 108 3e-23
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 108 3e-23
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 108 3e-23
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 108 3e-23
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 108 3e-23
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 108 3e-23
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 108 3e-23
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 107 6e-23
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 105 1e-22
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 105 1e-22
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 105 1e-22
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 105 1e-22
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 105 1e-22
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 105 1e-22
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 103 1e-21
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 103 1e-21
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 103 1e-21
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 103 1e-21
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 103 1e-21
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 103 1e-21
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 99 9e-21
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 99 9e-21
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 94 4e-19
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 94 4e-19
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 94 4e-19
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 92 2e-18
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 92 2e-18
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 92 2e-18
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 92 2e-18
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 92 2e-18
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 92 2e-18
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 92 2e-18
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 89 1e-17
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 89 1e-17
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 89 1e-17
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 89 1e-17
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 89 2e-17
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 89 2e-17
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 89 2e-17
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 89 2e-17
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 89 2e-17
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 89 2e-17
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 89 2e-17
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 89 2e-17
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 88 3e-17
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 88 4e-17
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 87 5e-17
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 86 1e-16
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 86 1e-16
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 86 1e-16
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 86 1e-16
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 86 1e-16
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 86 1e-16
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 86 1e-16
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 86 1e-16
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 86 1e-16
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 86 1e-16
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 86 2e-16
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 86 2e-16
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 86 2e-16
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 86 2e-16
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 85 4e-16
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 83 1e-15
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 81 3e-15
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 81 3e-15
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 79 2e-14
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 77 6e-14
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 75 4e-13
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 73 9e-13
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 73 9e-13
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 73 1e-12
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 67 6e-11
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 67 6e-11
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 67 6e-11
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 67 8e-11
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 67 8e-11
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 66 1e-10
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 66 1e-10
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 66 1e-10
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 66 1e-10
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 66 1e-10
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 66 1e-10
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 66 1e-10
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 66 1e-10
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 66 1e-10
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 66 1e-10
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 66 1e-10
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 64 4e-10
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 64 4e-10
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 64 4e-10
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 64 4e-10
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 64 5e-10
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 62 2e-09
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 62 2e-09
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 62 2e-09
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 58 3e-08
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 58 3e-08
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 57 6e-08
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 57 6e-08
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 57 6e-08
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 57 6e-08
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 57 8e-08
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 57 8e-08
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 56 1e-07
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 56 1e-07
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 56 1e-07
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 56 2e-07
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 56 2e-07
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 56 2e-07
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 56 2e-07
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 56 2e-07
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 56 2e-07
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 56 2e-07
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 56 2e-07
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 56 2e-07
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 56 2e-07
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 55 3e-07
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 55 3e-07
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 55 3e-07
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 55 3e-07
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 53 1e-06
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 53 1e-06
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 53 1e-06
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 52 2e-06
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 52 2e-06
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 52 2e-06
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 52 2e-06
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 52 2e-06
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 52 2e-06
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 52 2e-06
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 52 2e-06
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 52 2e-06
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 52 2e-06
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 52 2e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 52 3e-06
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 52 3e-06
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 52 3e-06
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 52 3e-06
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 52 3e-06
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 3e-06
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 3e-06
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 3e-06
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 3e-06
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 52 3e-06
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 52 3e-06
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 51 5e-06
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 51 5e-06
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 51 5e-06
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 51 5e-06
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 51 5e-06
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 51 5e-06
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 51 5e-06
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 51 5e-06
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 51 5e-06
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 51 5e-06
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 51 5e-06
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 50 7e-06
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 50 7e-06
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 50 7e-06
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 50 1e-05
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 50 1e-05
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 49 2e-05
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 49 2e-05
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 49 2e-05
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 49 2e-05
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 48 3e-05
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 48 3e-05
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 48 3e-05
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 48 3e-05
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 48 3e-05
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 48 3e-05
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 48 3e-05
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 48 3e-05
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 47 7e-05
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 47 7e-05
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 47 7e-05
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 47 9e-05
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 46 1e-04
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 46 2e-04
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 46 2e-04
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 46 2e-04
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 46 2e-04
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 46 2e-04
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 46 2e-04
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 46 2e-04
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 44 5e-04
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 44 5e-04
AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family... 41 0.004
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 40 0.008
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 40 0.008
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 40 0.008
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 40 0.008
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 40 0.010
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 38 0.031
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 38 0.031
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 38 0.031
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 38 0.031
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 38 0.031
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 38 0.031
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 38 0.031
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 38 0.031
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 38 0.041
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 38 0.055
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 38 0.055
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 38 0.055
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 37 0.095
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 37 0.095
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 36 0.13
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 36 0.13
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 36 0.13
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 36 0.13
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 36 0.13
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 36 0.13
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 36 0.13
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 36 0.13
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 36 0.13
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 36 0.13
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 36 0.13
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 36 0.13
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.13
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.13
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.13
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 36 0.13
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.13
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.13
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 36 0.13
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 36 0.13
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 36 0.13
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 36 0.13
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 36 0.13
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.22
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.22
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 36 0.22
AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein. 36 0.22
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 35 0.29
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 35 0.38
X58907-1|CAA41710.1| 369|Homo sapiens steroid 21-monooxygenase ... 34 0.51
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 34 0.51
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 34 0.51
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 33 1.6
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 33 1.6
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 33 1.6
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 33 1.6
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 33 1.6
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 33 1.6
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 33 1.6
AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1 pro... 33 1.6
AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1 pro... 33 1.6
AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1 pro... 33 1.6
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 33 1.6
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 32 2.1
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 32 2.1
DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450 ... 32 2.1
DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible cytoch... 32 2.1
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 32 2.1
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 32 2.1
BC032542-1|AAH32542.2| 1084|Homo sapiens fucokinase protein. 32 2.1
BC013735-1|AAH13735.1| 1032|Homo sapiens FUK protein protein. 32 2.1
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 32 2.1
AY829643-1|AAV67949.1| 1084|Homo sapiens fucokinase protein. 32 2.1
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 32 2.1
AK128387-1|BAC87413.1| 1090|Homo sapiens protein ( Homo sapiens ... 32 2.1
AK056456-1|BAB71190.1| 990|Homo sapiens protein ( Homo sapiens ... 32 2.1
AJ441184-1|CAD29647.1| 990|Homo sapiens L-fucose kinase protein. 32 2.1
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 32 2.1
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 32 2.1
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 32 2.7
BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein. 32 2.7
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 32 2.7
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 32 2.7
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 32 2.7
AK131099-1|BAC85149.1| 349|Homo sapiens FLJ00329 protein protein. 32 2.7
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 32 2.7
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 32 2.7
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 32 2.7
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 32 2.7
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 32 2.7
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 32 2.7
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 32 2.7
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 32 2.7
X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase ... 31 4.7
AK130941-1|BAC85469.1| 223|Homo sapiens protein ( Homo sapiens ... 31 6.3
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 148 bits (359), Expect = 2e-35
Identities = 81/217 (37%), Positives = 124/217 (57%), Gaps = 4/217 (1%)
Frame = +3
Query: 129 AIMIMWMLHRWQQSSRLFRLGNKLPG-PMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
A +++ +L R +R ++ +P A PLVG++LL + + + ++Y+E+Y
Sbjct: 27 ASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALL-MKPDGREFFQQIIEYTEEYR 85
Query: 306 --TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
+++ W GP +V L +A +VEVIL S IDKS Y+F +PWLG GLL S+G KWRS
Sbjct: 86 HMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRS 145
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVG-KTFDVHDYMSCVTVDILLETAM 656
RKM+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAM
Sbjct: 146 RRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAM 205
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFD 767
G Q +Y AV +M +I +R WL D
Sbjct: 206 GKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLD 242
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 148 bits (359), Expect = 2e-35
Identities = 81/217 (37%), Positives = 124/217 (57%), Gaps = 4/217 (1%)
Frame = +3
Query: 129 AIMIMWMLHRWQQSSRLFRLGNKLPG-PMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
A +++ +L R +R ++ +P A PLVG++LL + + + ++Y+E+Y
Sbjct: 27 ASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALL-MKPDGREFFQQIIEYTEEYR 85
Query: 306 --TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
+++ W GP +V L +A +VEVIL S IDKS Y+F +PWLG GLL S+G KWRS
Sbjct: 86 HMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRS 145
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVG-KTFDVHDYMSCVTVDILLETAM 656
RKM+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAM
Sbjct: 146 RRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAM 205
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFD 767
G Q +Y AV +M +I +R WL D
Sbjct: 206 GKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLD 242
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 148 bits (359), Expect = 2e-35
Identities = 81/217 (37%), Positives = 124/217 (57%), Gaps = 4/217 (1%)
Frame = +3
Query: 129 AIMIMWMLHRWQQSSRLFRLGNKLPG-PMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
A +++ +L R +R ++ +P A PLVG++LL + + + ++Y+E+Y
Sbjct: 27 ASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALL-MKPDGREFFQQIIEYTEEYR 85
Query: 306 --TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
+++ W GP +V L +A +VEVIL S IDKS Y+F +PWLG GLL S+G KWRS
Sbjct: 86 HMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRS 145
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVG-KTFDVHDYMSCVTVDILLETAM 656
RKM+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAM
Sbjct: 146 RRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAM 205
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFD 767
G Q +Y AV +M +I +R WL D
Sbjct: 206 GKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLD 242
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 142 bits (345), Expect = 1e-33
Identities = 79/214 (36%), Positives = 118/214 (55%), Gaps = 4/214 (1%)
Frame = +3
Query: 138 IMWM-LHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG--T 308
++W L W +S L G L + L V + L++ + + ++Y+E+Y
Sbjct: 8 LVWQKLLLWGAASALSLAGASLVLSL-LQRVASYALLMKPDGREFFQQIIEYTEEYRHMP 66
Query: 309 VVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRK 488
+++ W GP +V L +A +VEVIL S IDKS Y+F +PWLG GLL S+G KWRS RK
Sbjct: 67 LLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRK 126
Query: 489 MIAPTFHINILKSFMGVFNENSKSVVKKLRSEVG-KTFDVHDYMSCVTVDILLETAMGIT 665
M+ PTFH IL+ F+ + NE + +VKKL + + F+ Y++ +DI+ ETAMG
Sbjct: 127 MLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKN 186
Query: 666 KTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFD 767
Q +Y AV +M +I +R WL D
Sbjct: 187 IGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLD 220
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 108 bits (259), Expect = 3e-23
Identities = 53/163 (32%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 107 bits (256), Expect = 6e-23
Identities = 52/163 (31%), Positives = 94/163 (57%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FN++ + K L SE D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH+++ LH D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVSKRHHEILLHIDFLYYLT 250
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 105 bits (253), Expect = 1e-22
Identities = 57/182 (31%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Frame = +3
Query: 258 AEDLVKYALDYSEKYGTVVRAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFK 428
+E+ + Y + +G + W GP +V + ++ +L + I + Y F K
Sbjct: 70 SEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLK 129
Query: 429 PWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTF 599
PWLG+GLL+S+GEKW HR+M+ P FH NILK +M +FNE+ + K L SE
Sbjct: 130 PWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL 189
Query: 600 DVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFK 779
D+ +++S +T+D L + Q+ S +Y A++++ ++ +RH ++ L+ D ++
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYY 248
Query: 780 LT 785
LT
Sbjct: 249 LT 250
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 105 bits (253), Expect = 1e-22
Identities = 57/182 (31%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Frame = +3
Query: 258 AEDLVKYALDYSEKYGTVVRAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFK 428
+E+ + Y + +G + W GP +V + ++ +L + I + Y F K
Sbjct: 70 SEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLK 129
Query: 429 PWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTF 599
PWLG+GLL+S+GEKW HR+M+ P FH NILK +M +FNE+ + K L SE
Sbjct: 130 PWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL 189
Query: 600 DVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFK 779
D+ +++S +T+D L + Q+ S +Y A++++ ++ +RH ++ L+ D ++
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYY 248
Query: 780 LT 785
LT
Sbjct: 249 LT 250
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 105 bits (253), Expect = 1e-22
Identities = 57/182 (31%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Frame = +3
Query: 258 AEDLVKYALDYSEKYGTVVRAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFK 428
+E+ + Y + +G + W GP +V + ++ +L + I + Y F K
Sbjct: 70 SEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLK 129
Query: 429 PWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTF 599
PWLG+GLL+S+GEKW HR+M+ P FH NILK +M +FNE+ + K L SE
Sbjct: 130 PWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL 189
Query: 600 DVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFK 779
D+ +++S +T+D L + Q+ S +Y A++++ ++ +RH ++ L+ D ++
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYY 248
Query: 780 LT 785
LT
Sbjct: 249 LT 250
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 105 bits (253), Expect = 1e-22
Identities = 54/163 (33%), Positives = 92/163 (56%), Gaps = 6/163 (3%)
Frame = +3
Query: 315 RAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP V+ N + ++N+ I + Y F KPWLG+GLL+S+GEKW HR
Sbjct: 89 KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAM 656
+M+ P FH NILK +M +FNE+ + K L S+ D+ +++S +T+D L +
Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDMFEHISLMTLDSLQKCVF 208
Query: 657 GITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A++++ ++ +RH ++ L+ D ++ LT
Sbjct: 209 SFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYYLT 250
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 105 bits (253), Expect = 1e-22
Identities = 57/182 (31%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Frame = +3
Query: 258 AEDLVKYALDYSEKYGTVVRAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFK 428
+E+ + Y + +G + W GP +V + ++ +L + I + Y F K
Sbjct: 70 SEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLK 129
Query: 429 PWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTF 599
PWLG+GLL+S+GEKW HR+M+ P FH NILK +M +FNE+ + K L SE
Sbjct: 130 PWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL 189
Query: 600 DVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFK 779
D+ +++S +T+D L + Q+ S +Y A++++ ++ +RH ++ L+ D ++
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYY 248
Query: 780 LT 785
LT
Sbjct: 249 LT 250
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 105 bits (253), Expect = 1e-22
Identities = 57/182 (31%), Positives = 100/182 (54%), Gaps = 6/182 (3%)
Frame = +3
Query: 258 AEDLVKYALDYSEKYGTVVRAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFK 428
+E+ + Y + +G + W GP +V + ++ +L + I + Y F K
Sbjct: 70 SEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLK 129
Query: 429 PWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTF 599
PWLG+GLL+S+GEKW HR+M+ P FH NILK +M +FNE+ + K L SE
Sbjct: 130 PWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL 189
Query: 600 DVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFK 779
D+ +++S +T+D L + Q+ S +Y A++++ ++ +RH ++ L+ D ++
Sbjct: 190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDFLYY 248
Query: 780 LT 785
LT
Sbjct: 249 LT 250
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 103 bits (246), Expect = 1e-21
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 261 EDLVKYALDYSEKYGTVVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPEY--RFFKP 431
E+ +K + S Y W GP + + L + + I N+ I RF KP
Sbjct: 71 EEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKP 130
Query: 432 WLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFD 602
WLGEG+L+S G+KW HR+M+ P FH NILKS++ +FN+++ ++ K L SE D
Sbjct: 131 WLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLD 190
Query: 603 VHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKL 782
+ +++S +T+D L + Q+ S +Y ++++ ++ +R + H D ++ L
Sbjct: 191 MFEHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYL 249
Query: 783 T 785
+
Sbjct: 250 S 250
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 103 bits (246), Expect = 1e-21
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 261 EDLVKYALDYSEKYGTVVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPEY--RFFKP 431
E+ +K + S Y W GP + + L + + I N+ I RF KP
Sbjct: 71 EEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKP 130
Query: 432 WLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFD 602
WLGEG+L+S G+KW HR+M+ P FH NILKS++ +FN+++ ++ K L SE D
Sbjct: 131 WLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLD 190
Query: 603 VHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKL 782
+ +++S +T+D L + Q+ S +Y ++++ ++ +R + H D ++ L
Sbjct: 191 MFEHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYL 249
Query: 783 T 785
+
Sbjct: 250 S 250
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 103 bits (246), Expect = 1e-21
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 261 EDLVKYALDYSEKYGTVVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPEY--RFFKP 431
E+ +K + S Y W GP + + L + + I N+ I RF KP
Sbjct: 71 EEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKP 130
Query: 432 WLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFD 602
WLGEG+L+S G+KW HR+M+ P FH NILKS++ +FN+++ ++ K L SE D
Sbjct: 131 WLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLD 190
Query: 603 VHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKL 782
+ +++S +T+D L + Q+ S +Y ++++ ++ +R + H D ++ L
Sbjct: 191 MFEHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYL 249
Query: 783 T 785
+
Sbjct: 250 S 250
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 103 bits (246), Expect = 1e-21
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 261 EDLVKYALDYSEKYGTVVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPEY--RFFKP 431
E+ +K + S Y W GP + + L + + I N+ I RF KP
Sbjct: 5 EEGLKNSTQMSATYSQGFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKP 64
Query: 432 WLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFD 602
WLGEG+L+S G+KW HR+M+ P FH NILKS++ +FN+++ ++ K L SE D
Sbjct: 65 WLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLD 124
Query: 603 VHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKL 782
+ +++S +T+D L + Q+ S +Y ++++ ++ +R + H D ++ L
Sbjct: 125 MFEHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYL 183
Query: 783 T 785
+
Sbjct: 184 S 184
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 103 bits (246), Expect = 1e-21
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 261 EDLVKYALDYSEKYGTVVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPEY--RFFKP 431
E+ +K + S Y W GP + + L + + I N+ I RF KP
Sbjct: 71 EEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKP 130
Query: 432 WLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFD 602
WLGEG+L+S G+KW HR+M+ P FH NILKS++ +FN+++ ++ K L SE D
Sbjct: 131 WLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLD 190
Query: 603 VHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKL 782
+ +++S +T+D L + Q+ S +Y ++++ ++ +R + H D ++ L
Sbjct: 191 MFEHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYL 249
Query: 783 T 785
+
Sbjct: 250 S 250
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 103 bits (246), Expect = 1e-21
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 6/181 (3%)
Frame = +3
Query: 261 EDLVKYALDYSEKYGTVVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPEY--RFFKP 431
E+ +K + S Y W GP + + L + + I N+ I RF KP
Sbjct: 71 EEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKP 130
Query: 432 WLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFD 602
WLGEG+L+S G+KW HR+M+ P FH NILKS++ +FN+++ ++ K L SE D
Sbjct: 131 WLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLD 190
Query: 603 VHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKL 782
+ +++S +T+D L + Q+ S +Y ++++ ++ +R + H D ++ L
Sbjct: 191 MFEHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILELSALVEKRSQHILQHMDFLYYL 249
Query: 783 T 785
+
Sbjct: 250 S 250
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 99 bits (238), Expect = 9e-21
Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 414 YRFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSE 584
Y F KPWLG+GLL+S G+KW HR+M+ P FH NILK +M +FN++ + K L SE
Sbjct: 125 YGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASE 184
Query: 585 VGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHF 764
D+ +++S +T+D L + Q+ S +Y A++++ + +R+ ++ LH
Sbjct: 185 GSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPS-EYIAAILELSAFVEKRNQQILLHT 243
Query: 765 DAIFKLT 785
D ++ LT
Sbjct: 244 DFLYYLT 250
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 99 bits (238), Expect = 9e-21
Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 414 YRFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSE 584
Y F KPWLG+GLL+S G+KW HR+M+ P FH NILK +M +FN++ + K L SE
Sbjct: 125 YGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASE 184
Query: 585 VGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHF 764
D+ +++S +T+D L + Q+ S +Y A++++ + +R+ ++ LH
Sbjct: 185 GSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPS-EYIAAILELSAFVEKRNQQILLHT 243
Query: 765 DAIFKLT 785
D ++ LT
Sbjct: 244 DFLYYLT 250
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/162 (30%), Positives = 90/162 (55%), Gaps = 6/162 (3%)
Frame = +3
Query: 309 VVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRS 479
V+ W GP L ++ L + ++ +L + I + Y F KPWLG+GLL+S G+KW
Sbjct: 95 VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSR 154
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLET 650
HR+++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 155 HRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKC 214
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIF 776
Q+ S DY A++++ + +R Y++ + D I+
Sbjct: 215 VFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIY 255
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/162 (30%), Positives = 90/162 (55%), Gaps = 6/162 (3%)
Frame = +3
Query: 309 VVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRS 479
V+ W GP L ++ L + ++ +L + I + Y F KPWLG+GLL+S G+KW
Sbjct: 95 VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSR 154
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLET 650
HR+++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 155 HRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKC 214
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIF 776
Q+ S DY A++++ + +R Y++ + D I+
Sbjct: 215 VFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIY 255
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 94.3 bits (224), Expect = 4e-19
Identities = 49/162 (30%), Positives = 90/162 (55%), Gaps = 6/162 (3%)
Frame = +3
Query: 309 VVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRS 479
V+ W GP L ++ L + ++ +L + I + Y F KPWLG+GLL+S G+KW
Sbjct: 95 VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSR 154
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLET 650
HR+++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 155 HRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKC 214
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIF 776
Q+ S DY A++++ + +R Y++ + D I+
Sbjct: 215 VFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIY 255
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 92.3 bits (219), Expect = 2e-18
Identities = 48/162 (29%), Positives = 89/162 (54%), Gaps = 6/162 (3%)
Frame = +3
Query: 309 VVRAWAGPKL-VVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRS 479
V+ W GP L ++ L + ++ +L + + Y F KPWLG+GLL+S G+KW
Sbjct: 95 VLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGLLLSKGDKWSR 154
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLET 650
HR+++ P FH +ILK +M +FN+++ + K L + D+ +++S +T+D L +
Sbjct: 155 HRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKC 214
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIF 776
Q+ S DY A++++ + +R Y++ + D I+
Sbjct: 215 VFSYNSNCQEKMS-DYISAIIELSALSVRRQYRLHHYLDFIY 255
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 51/161 (31%), Positives = 92/161 (57%), Gaps = 6/161 (3%)
Frame = +3
Query: 321 WAGPKL-VVFLTDANDVEVILNSQIHI-DKSPE-YRFFKPWLGEGLLISSGEKWRSHRKM 491
W GP ++ L + V ++N+ I DK Y+ KPWLG+GLL+S G+KWR HR++
Sbjct: 91 WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRL 150
Query: 492 IAPTFHINILKSFMGVFNENSKSVVKK---LRSEVGKTFDVHDYMSCVTVDILLETAMGI 662
+ P FH NILK ++ +F++++ + K L E DV +++S +T+D L +
Sbjct: 151 LTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSF 210
Query: 663 TKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q+ S +Y A+M++ ++ +R+ + + + D ++ LT
Sbjct: 211 DSNCQEKPS-EYITAIMELSALVVKRNNQFFRYKDFLYFLT 250
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 91.9 bits (218), Expect = 2e-18
Identities = 62/224 (27%), Positives = 105/224 (46%), Gaps = 4/224 (1%)
Frame = +3
Query: 126 LAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
LA+ ++ + + + RL R P P +G+ I E L + EKY
Sbjct: 22 LALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII----EKYP 77
Query: 306 TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHR 485
W GP F D L S+ +F P LG+GL G KW HR
Sbjct: 78 RAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHR 137
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAM 656
+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 138 RLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAF 197
Query: 657 GITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 198 SKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 241
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 91.9 bits (218), Expect = 2e-18
Identities = 62/224 (27%), Positives = 105/224 (46%), Gaps = 4/224 (1%)
Frame = +3
Query: 126 LAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
LA+ ++ + + + RL R P P +G+ I E L + EKY
Sbjct: 22 LALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII----EKYP 77
Query: 306 TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHR 485
W GP F D L S+ +F P LG+GL G KW HR
Sbjct: 78 RAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHR 137
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAM 656
+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 138 RLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAF 197
Query: 657 GITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 198 SKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 241
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 91.9 bits (218), Expect = 2e-18
Identities = 62/224 (27%), Positives = 105/224 (46%), Gaps = 4/224 (1%)
Frame = +3
Query: 126 LAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
LA+ ++ + + + RL R P P +G+ I E L + EKY
Sbjct: 22 LALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII----EKYP 77
Query: 306 TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHR 485
W GP F D L S+ +F P LG+GL G KW HR
Sbjct: 78 RAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHR 137
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAM 656
+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 138 RLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAF 197
Query: 657 GITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 198 SKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 241
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 91.9 bits (218), Expect = 2e-18
Identities = 62/224 (27%), Positives = 105/224 (46%), Gaps = 4/224 (1%)
Frame = +3
Query: 126 LAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
LA+ ++ + + + RL R P P +G+ I E L + EKY
Sbjct: 22 LALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII----EKYP 77
Query: 306 TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHR 485
W GP F D L S+ +F P LG+GL G KW HR
Sbjct: 78 RAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHR 137
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAM 656
+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 138 RLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAF 197
Query: 657 GITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 198 SKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 241
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 91.9 bits (218), Expect = 2e-18
Identities = 62/224 (27%), Positives = 105/224 (46%), Gaps = 4/224 (1%)
Frame = +3
Query: 126 LAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
LA+ ++ + + + RL R P P +G+ I E L + EKY
Sbjct: 22 LALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII----EKYP 77
Query: 306 TVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHR 485
W GP F D L S+ +F P LG+GL G KW HR
Sbjct: 78 RAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHR 137
Query: 486 KMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILLETAM 656
+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI+++ A
Sbjct: 138 RLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAF 197
Query: 657 GITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 198 SKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 241
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 89.4 bits (212), Expect = 1e-17
Identities = 57/226 (25%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L +++++ ++ +Q+ + R + P P A G+ K+ E V + L EK
Sbjct: 20 LCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFE--VYHKL--MEK 75
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
Y V W GP + F D IL + + ++ + W+G GL+ G KW+
Sbjct: 76 YPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKK 135
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETA 653
HR+++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 136 HRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCA 195
Query: 654 MGITKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
+ Q D+ Y AV + I +QR H D +FK +S
Sbjct: 196 FSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSS 241
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 89.4 bits (212), Expect = 1e-17
Identities = 57/226 (25%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L +++++ ++ +Q+ + R + P P A G+ K+ E V + L EK
Sbjct: 20 LCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFE--VYHKL--MEK 75
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
Y V W GP + F D IL + + ++ + W+G GL+ G KW+
Sbjct: 76 YPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKK 135
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETA 653
HR+++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 136 HRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCA 195
Query: 654 MGITKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
+ Q D+ Y AV + I +QR H D +FK +S
Sbjct: 196 FSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSS 241
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 89.4 bits (212), Expect = 1e-17
Identities = 57/226 (25%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L +++++ ++ +Q+ + R + P P A G+ K+ E V + L EK
Sbjct: 20 LCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFE--VYHKL--MEK 75
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
Y V W GP + F D IL + + ++ + W+G GL+ G KW+
Sbjct: 76 YPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKK 135
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETA 653
HR+++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 136 HRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCA 195
Query: 654 MGITKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
+ Q D+ Y AV + I +QR H D +FK +S
Sbjct: 196 FSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSS 241
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 89.4 bits (212), Expect = 1e-17
Identities = 57/226 (25%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L +++++ ++ +Q+ + R + P P A G+ K+ E V + L EK
Sbjct: 20 LCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKEFYPVKEFE--VYHKL--MEK 75
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
Y V W GP + F D IL + + ++ + W+G GL+ G KW+
Sbjct: 76 YPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKK 135
Query: 480 HRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILLETA 653
HR+++ P F+I+ILK F+ + +E+ + ++ K + + ++ ++S +T+D +++ A
Sbjct: 136 HRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCA 195
Query: 654 MGITKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
+ Q D+ Y AV + I +QR H D +FK +S
Sbjct: 196 FSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSS 241
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 108/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K + GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 88.6 bits (210), Expect = 2e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 88.2 bits (209), Expect = 3e-17
Identities = 60/225 (26%), Positives = 109/225 (48%), Gaps = 3/225 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRRTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKTTQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 240
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 87.8 bits (208), Expect = 4e-17
Identities = 51/168 (30%), Positives = 85/168 (50%), Gaps = 4/168 (2%)
Frame = +3
Query: 294 EKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKW 473
EKY W GP F D L S+ +F P LG+GL G KW
Sbjct: 9 EKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKW 68
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILL 644
HR+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI++
Sbjct: 69 FQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIM 128
Query: 645 ETAMGITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
+ A Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 129 KCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 176
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 87.4 bits (207), Expect = 5e-17
Identities = 51/168 (30%), Positives = 85/168 (50%), Gaps = 4/168 (2%)
Frame = +3
Query: 294 EKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKW 473
EKY W GP F D L S+ +F P LG+GL G KW
Sbjct: 73 EKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKW 132
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVV---KKLRSEVGKTFDVHDYMSCVTVDILL 644
HR+++ P FH NILK+++ V + K ++ +K+ S + +V+++++ +++DI++
Sbjct: 133 FQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVM 192
Query: 645 ETAMGITKTTQDAASFD-YAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
+ A Q ++ D YA A+ ++ II R Y + H D IFKL+
Sbjct: 193 KCAFSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLS 240
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 86.2 bits (204), Expect = 1e-16
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 4/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T + Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 241
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 4/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T + Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 241
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 4/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T + Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 241
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 85.8 bits (203), Expect = 2e-16
Identities = 60/226 (26%), Positives = 110/226 (48%), Gaps = 4/226 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + ++H + L + +K PGP L G++L I + D V + ++ +
Sbjct: 20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPE-YRFFKPWLGEGLLISSGEKWR 476
+ W G + D + S+ K+P+ Y FF W+G GLL+ G KW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGD-PKAPDVYDFFLQWIGRGLLVLEGPKWL 135
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHDYMSCVTVDILLET 650
HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+ + + ++ L++
Sbjct: 136 QHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC 195
Query: 651 AMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
G T + Y +AV + ++ QR H D I+ LT
Sbjct: 196 TFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 241
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 84.6 bits (200), Expect = 4e-16
Identities = 46/169 (27%), Positives = 89/169 (52%), Gaps = 4/169 (2%)
Frame = +3
Query: 294 EKYGTVVRAWAGPKLVVF-LTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEK 470
EKY V W GP + F + D + V+++L Q + ++ + W+G GL+ G K
Sbjct: 74 EKYPCAVPLWVGPFTMFFNIHDPDYVKILLKRQ-DPKSAVSHKILESWVGRGLVTLDGSK 132
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKT--FDVHDYMSCVTVDILL 644
W+ HR+++ P F+I+ILK F+ + +++ + ++ K + + ++ ++S +T+D ++
Sbjct: 133 WKKHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIM 192
Query: 645 ETAMGITKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
+ A + Q D+ Y AV + I +QR H D +FK +S
Sbjct: 193 KCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSS 241
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/227 (24%), Positives = 111/227 (48%), Gaps = 4/227 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L +++++ ++ +Q+ R + P P A G+ K+ E Y + EK
Sbjct: 20 LCMSLLLFQVIRLYQRRRWTIRAMHLFPAPPAHWFYGHKESYPVKEFE---VYP-ELMEK 75
Query: 300 YGTVVRAWAGPKLVVF-LTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
Y V W GP + F + D + V+++L Q + + ++ + W+G GL+ G KW+
Sbjct: 76 YPCAVPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWK 134
Query: 477 SHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLET 650
HR+++ P F+I+ILK F+ + +++ + ++ K + ++ ++S +T+ +++
Sbjct: 135 KHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAHNSRLELFQHVSLMTLHSIMKC 194
Query: 651 AMGITKTTQ-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
A + Q D+ Y AV + I +QR H D +FK +S
Sbjct: 195 AFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSS 241
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 81.4 bits (192), Expect = 3e-15
Identities = 46/159 (28%), Positives = 85/159 (53%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F PW+G LL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DSKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ + ++S +T+D ++++A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + +++ R + DAI+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLSSLVFCRMRNAFHENDAIYSLTS 247
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 81.4 bits (192), Expect = 3e-15
Identities = 46/159 (28%), Positives = 84/159 (52%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F PW+G LL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ + ++S +T+D ++++A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + N++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTS 247
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 78.6 bits (185), Expect = 2e-14
Identities = 45/159 (28%), Positives = 84/159 (52%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F PW+G LL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ + ++S +T+D ++++A +
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + +++ R + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNSLVFCRMRNAFHENDTIYSLTS 247
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 77.4 bits (182), Expect = 6e-14
Identities = 33/82 (40%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Frame = +3
Query: 315 RAWAGP-KLVVFLTDANDVEVILNSQIHIDKSPE--YRFFKPWLGEGLLISSGEKWRSHR 485
+ W GP ++ L + + ++N+ I + Y F +PWLG+GLL+S+G+KW HR
Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148
Query: 486 KMIAPTFHINILKSFMGVFNEN 551
+M+ P FH NILK +M +FNE+
Sbjct: 149 RMLTPAFHFNILKPYMKIFNES 170
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 74.5 bits (175), Expect = 4e-13
Identities = 46/159 (28%), Positives = 84/159 (52%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF P +G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPRIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A +
Sbjct: 149 AFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + +++ + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTS 247
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 73.3 bits (172), Expect = 9e-13
Identities = 45/159 (28%), Positives = 84/159 (52%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F P +G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A +
Sbjct: 149 AFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + +++ + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTS 247
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 73.3 bits (172), Expect = 9e-13
Identities = 45/159 (28%), Positives = 84/159 (52%), Gaps = 3/159 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F P +G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETAMGITKTT 674
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A +
Sbjct: 149 AFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSI 208
Query: 675 Q-DAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLTS 788
Q D S Y A+ + +++ + D I+ LTS
Sbjct: 209 QVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTS 247
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 72.9 bits (171), Expect = 1e-12
Identities = 37/113 (32%), Positives = 66/113 (58%), Gaps = 2/113 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL YRF PW+G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETA 653
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D +++ A
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 67.3 bits (157), Expect = 6e-11
Identities = 36/119 (30%), Positives = 64/119 (53%), Gaps = 3/119 (2%)
Frame = +3
Query: 438 GEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHD 611
G GLL+ G KW HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 612 YMSCVTVDILLETAMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
+ + ++ L++ G T + Y +AV + ++ QR H D I+ LT
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 226
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 67.3 bits (157), Expect = 6e-11
Identities = 36/119 (30%), Positives = 64/119 (53%), Gaps = 3/119 (2%)
Frame = +3
Query: 438 GEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHD 611
G GLL+ G KW HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 612 YMSCVTVDILLETAMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
+ + ++ L++ G T + Y +AV + ++ QR H D I+ LT
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 226
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 67.3 bits (157), Expect = 6e-11
Identities = 36/119 (30%), Positives = 64/119 (53%), Gaps = 3/119 (2%)
Frame = +3
Query: 438 GEGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKL--RSEVGKTFDVHD 611
G GLL+ G KW HRK++ P FH ++LK ++ VF E+++ ++ K ++ GK+FD+
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 612 YMSCVTVDILLETAMGITKT-TQDAASFDYAMAVMKMCNIIHQRHYKVWLHFDAIFKLT 785
+ + ++ L++ G T + Y +AV + ++ QR H D I+ LT
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLT 226
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 66.9 bits (156), Expect = 8e-11
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVCGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 66.9 bits (156), Expect = 8e-11
Identities = 35/113 (30%), Positives = 66/113 (58%), Gaps = 2/113 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F P +G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETA 653
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A
Sbjct: 149 AFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSA 201
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 66.1 bits (154), Expect = 1e-10
Identities = 35/113 (30%), Positives = 66/113 (58%), Gaps = 2/113 (1%)
Frame = +3
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAP 500
W G K+ V L D + ++VIL Y+F P +G GLL+ +G+ W HR+M+ P
Sbjct: 91 WGG-KVRVQLYDPDYMKVILGRS-DPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTP 148
Query: 501 TFHINILKSFMGVFNENSKSVVKKLRSEVGK--TFDVHDYMSCVTVDILLETA 653
FH +ILK ++G+ ++ + ++ K +G+ +V ++S +T+D ++++A
Sbjct: 149 AFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSA 201
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLF-RLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF RLG +PGP LPL+GN L + L K+ + +
Sbjct: 13 LLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVL----SYRQGLWKFDTECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG + + G V+ +TD + + +L + + R P ++ + ++ E+
Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAISLAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 GTSFGV 191
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLF-RLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF RLG +PGP LPL+GN L + L K+ + +
Sbjct: 13 LLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVL----SYRQGLWKFDTECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG + + G V+ +TD + + +L + + R P ++ + ++ E+
Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAISLAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 GTSFGV 191
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLF-RLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF RLG +PGP LPL+GN L + L K+ + +
Sbjct: 13 LLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVL----SYRQGLWKFDTECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG + + G V+ +TD + + +L + + R P ++ + ++ E+
Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAISLAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 GTSFGV 191
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLF-RLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF RLG +PGP LPL+GN L + L K+ + +
Sbjct: 13 LLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVL----SYRQGLWKFDTECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG + + G V+ +TD + + +L + + R P ++ + ++ E+
Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAISLAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 GTSFGV 191
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 64.1 bits (149), Expect = 5e-10
Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLF-RLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF RLG +PGP LPL+GN L + L K+ + +
Sbjct: 13 LLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVL----SYRQGLWKFDTECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG + + G V+ +TD + + +L + + R P ++ + ++ E+
Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAISLAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 GTSFGV 191
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG V + G + V+ +TD + ++++L + + + F ++ + I+ E+W
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLE 647
+ R +++PTF LK + + + +V+ LR E GK + D ++D++
Sbjct: 127 KRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITS 186
Query: 648 TAMGI 662
++ G+
Sbjct: 187 SSFGV 191
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 LLLAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG V + G + V+ +TD + ++++L + + + F ++ + I+ E+W
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLE 647
+ R +++PTF LK + + + +V+ LR E GK + D ++D++
Sbjct: 127 KRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITS 186
Query: 648 TAMGI 662
++ G+
Sbjct: 187 SSFGV 191
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/186 (24%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S LF+ LG +PGP LP +GN L + + ++ +
Sbjct: 13 VLVATSLVLLYIYGTHSHGLFKKLG--IPGPTPLPFLGNIL----SYHKGFCMFDMECHK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KYG V + G + V+ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + D ++D++
Sbjct: 126 WKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVIT 185
Query: 645 ETAMGI 662
T+ G+
Sbjct: 186 STSFGV 191
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 58.4 bits (135), Expect = 3e-08
Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 8/154 (5%)
Frame = +3
Query: 282 LDYSEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGL---- 449
LD+++KYG VVR K V +T V+ L S + S YR + GE L
Sbjct: 65 LDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQG 124
Query: 450 LIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV-GKT-FDVHDYM 617
L+S + E+W R++I F + L S M FNE ++ +V+ L ++ G+T + D +
Sbjct: 125 LVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDML 184
Query: 618 SCVTVDILLETAMGITKTTQDAASFDYAMAVMKM 719
+ +DIL + A G+ + A + AV M
Sbjct: 185 TYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLM 218
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 58.4 bits (135), Expect = 3e-08
Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 8/154 (5%)
Frame = +3
Query: 282 LDYSEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGL---- 449
LD+++KYG VVR K V +T V+ L S + S YR + GE L
Sbjct: 65 LDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQG 124
Query: 450 LIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV-GKT-FDVHDYM 617
L+S + E+W R++I F + L S M FNE ++ +V+ L ++ G+T + D +
Sbjct: 125 LVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDML 184
Query: 618 SCVTVDILLETAMGITKTTQDAASFDYAMAVMKM 719
+ +DIL + A G+ + A + AV M
Sbjct: 185 TYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLM 218
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 57.2 bits (132), Expect = 6e-08
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L + E +
Sbjct: 32 PGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL 88
Query: 378 LNSQIHIDKSPEYRFFKPWL-GEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
++ + P+ G G++ ++G +W+ R+ T + +S E
Sbjct: 89 VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQE 148
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNI 728
++ ++++LR G D +T +I+ G QD +KM N+
Sbjct: 149 EAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQD-------QEFLKMLNL 201
Query: 729 IHQRHYKVWLHFDAIFKLTS 788
+Q + F +F+L S
Sbjct: 202 FYQTFSLISSVFGQLFELFS 221
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 57.2 bits (132), Expect = 6e-08
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L + E +
Sbjct: 32 PGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL 88
Query: 378 LNSQIHIDKSPEYRFFKPWL-GEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
++ + P+ G G++ ++G +W+ R+ T + +S E
Sbjct: 89 VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQE 148
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNI 728
++ ++++LR G D +T +I+ G QD +KM N+
Sbjct: 149 EAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQD-------QEFLKMLNL 201
Query: 729 IHQRHYKVWLHFDAIFKLTS 788
+Q + F +F+L S
Sbjct: 202 FYQTFSLISSVFGQLFELFS 221
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 57.2 bits (132), Expect = 6e-08
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L + E +
Sbjct: 32 PGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL 88
Query: 378 LNSQIHIDKSPEYRFFKPWL-GEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
++ + P+ G G++ ++G +W+ R+ T + +S E
Sbjct: 89 VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQE 148
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNI 728
++ ++++LR G D +T +I+ G QD +KM N+
Sbjct: 149 EAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQD-------QEFLKMLNL 201
Query: 729 IHQRHYKVWLHFDAIFKLTS 788
+Q + F +F+L S
Sbjct: 202 FYQTFSLISSVFGQLFELFS 221
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 57.2 bits (132), Expect = 6e-08
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L + E +
Sbjct: 32 PGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL 88
Query: 378 LNSQIHIDKSPEYRFFKPWL-GEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
++ + P+ G G++ ++G +W+ R+ T + +S E
Sbjct: 89 VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQE 148
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNI 728
++ ++++LR G D +T +I+ G QD +KM N+
Sbjct: 149 EAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQD-------QEFLKMLNL 201
Query: 729 IHQRHYKVWLHFDAIFKLTS 788
+Q + F +F+L S
Sbjct: 202 FYQTFSLISSVFGQLFELFS 221
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 56.8 bits (131), Expect = 8e-08
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L + E +
Sbjct: 32 PGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL 88
Query: 378 LNSQIHIDKSPEYRFFKPWL-GEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
++ + P+ G G++ ++G +W+ R+ T + +S E
Sbjct: 89 VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQE 148
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNI 728
++ ++++LR G D +T +I+ G QD +KM N+
Sbjct: 149 EAQCLIEELRKSKGALMDPTFLFHSITANIICSIVFGKRFHYQD-------QEFLKMLNL 201
Query: 729 IHQRHYKVWLHFDAIFKLTS 788
+Q + F +F+L S
Sbjct: 202 FYQTFSLISSVFGQLFELFS 221
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 56.8 bits (131), Expect = 8e-08
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L + E +
Sbjct: 32 PGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREAL 88
Query: 378 LNSQIHIDKSPEYRFFKPWL-GEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
++ + P+ G G++ ++G +W+ R+ T + +S E
Sbjct: 89 VDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERTQE 148
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKMCNI 728
++ ++++LR G D +T +I+ G QD +KM N+
Sbjct: 149 EAQCLIEELRKSKGALMDATFLFHSITANIICSIVFGKRFHYQD-------QEFLKMLNL 201
Query: 729 IHQRHYKVWLHFDAIFKLTS 788
+Q + F +F+L S
Sbjct: 202 FYQTFSLISSVFGQLFELFS 221
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D H +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDAHRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/166 (28%), Positives = 79/166 (47%), Gaps = 9/166 (5%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP LP++GN LL+ ++D++ S++YG++ GP+ VV L+ V
Sbjct: 28 GKLPPGPRPLPILGNLLLLC---SQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAV 84
Query: 369 -EVILNSQIHIDKSPEY-RFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSF-MGV 539
E +++ +Y FF G G+ SSG++W+ R+ F I IL++F MG
Sbjct: 85 KEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGK 139
Query: 540 FN------ENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ E ++ +LR G+ FD +S +I+ G
Sbjct: 140 RSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFG 185
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D H +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDAHRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/185 (22%), Positives = 88/185 (47%), Gaps = 4/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
+L+A ++ + S +LF+ LG +PGP LP +G L L L + + +E
Sbjct: 13 VLVATSLVLLYIYGTHSHKLFKKLG--IPGPTPLPFLGTILFYL----RGLWNFDRECNE 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP-WLGEGLLISSGEKW 473
KYG + + G + ++ + D + ++ +L + + + + +L L + E+W
Sbjct: 67 KYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEW 126
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV--GKTFDVHDYMSCVTVDILLE 647
+ R +++P F K + + ++ +V+ LR E K+ ++ D+ T+D++
Sbjct: 127 KRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITG 186
Query: 648 TAMGI 662
T G+
Sbjct: 187 TLFGV 191
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/187 (22%), Positives = 92/187 (49%), Gaps = 5/187 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF+ LG +PGP LP +GN+L + + ++ +
Sbjct: 13 LLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSF----RKGYWTFDMECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KY V + + ++ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVIT 185
Query: 645 ETAMGIT 665
T+ G++
Sbjct: 186 STSFGVS 192
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/187 (22%), Positives = 92/187 (49%), Gaps = 5/187 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF+ LG +PGP LP +GN+L + + ++ +
Sbjct: 13 LLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSF----RKGYWTFDMECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KY V + + ++ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVIT 185
Query: 645 ETAMGIT 665
T+ G++
Sbjct: 186 STSFGVS 192
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/187 (22%), Positives = 92/187 (49%), Gaps = 5/187 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF+ LG +PGP LP +GN+L + + ++ +
Sbjct: 13 LLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSF----RKGYWTFDMECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KY V + + ++ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVIT 185
Query: 645 ETAMGIT 665
T+ G++
Sbjct: 186 STSFGVS 192
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 55.2 bits (127), Expect = 3e-07
Identities = 43/187 (22%), Positives = 92/187 (49%), Gaps = 5/187 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFR-LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF+ LG +PGP LP +GN+L + + ++ +
Sbjct: 13 LLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSF----RKGYWTFDMECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEK 470
KY V + + ++ +TD + ++ +L + + R F P ++ + I+ E+
Sbjct: 67 KYRKVWGIYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEE 125
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILL 644
W+ R +++PTF LK + + + +V+ LR +E GK + ++D++
Sbjct: 126 WKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVIT 185
Query: 645 ETAMGIT 665
T+ G++
Sbjct: 186 STSFGVS 192
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP L ++GN LL+ ++D++ S++YG++ GP+ VV L+ V
Sbjct: 28 GKLPPGPRPLSILGNLLLLC---SQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAV 84
Query: 369 -EVILNSQIHIDKSPEY-RFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSF-MGV 539
E +++ +Y FF G G+ SSG++W+ R+ F I IL++F MG
Sbjct: 85 KEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGK 139
Query: 540 FN------ENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ E ++ +LR G+ FD +S +I+ G
Sbjct: 140 RSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFG 185
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP L ++GN LL+ ++D++ S++YG++ GP+ VV L+ V
Sbjct: 28 GKLPPGPRPLSILGNLLLLC---SQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAV 84
Query: 369 -EVILNSQIHIDKSPEY-RFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSF-MGV 539
E +++ +Y FF G G+ SSG++W+ R+ F I IL++F MG
Sbjct: 85 KEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGK 139
Query: 540 FN------ENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ E ++ +LR G+ FD +S +I+ G
Sbjct: 140 RSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFG 185
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP L ++GN LL+ ++D++ S++YG++ GP+ VV L+ V
Sbjct: 28 GKLPPGPRPLSILGNLLLLC---SQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAV 84
Query: 369 -EVILNSQIHIDKSPEY-RFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSF-MGV 539
E +++ +Y FF G G+ SSG++W+ R+ F I IL++F MG
Sbjct: 85 KEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGK 139
Query: 540 FN------ENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ E ++ +LR G+ FD +S +I+ G
Sbjct: 140 RSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFG 185
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 4/161 (2%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L +
Sbjct: 28 GTLPPGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAI 84
Query: 369 EVIL--NSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMG 536
L N++ + + G G+L ++G +W+ R+ T + +S
Sbjct: 85 REALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVEE 144
Query: 537 VFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ ++ ++++LR G D +T +I+ G
Sbjct: 145 RIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFG 185
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 4/161 (2%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP LPL+GN LL + ++ L+K L + EKYG V GP+ VV L +
Sbjct: 28 GTLPPGPRPLPLLGN-LLQMDRRG--LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAI 84
Query: 369 EVIL--NSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMG 536
L N++ + + G G+L ++G +W+ R+ T + +S
Sbjct: 85 REALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVEE 144
Query: 537 VFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ ++ ++++LR G D +T +I+ G
Sbjct: 145 RIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFG 185
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 52.0 bits (119), Expect = 2e-06
Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 6 LLVCLTVMVLMSVWQQRKNKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 59
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 60 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 119
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D +D L
Sbjct: 120 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLS 170
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 171 RTVSNVISSIVFGDRFDY 188
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFD 602
+ R+ F I L+ F GV + + ++++ E G D
Sbjct: 124 AKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLID 158
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFD 602
+ R+ F I L+ F GV + + ++++ E G D
Sbjct: 124 AKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLID 158
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFD 602
+ R+ F I L+ F GV + + ++++ E G D
Sbjct: 124 AKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLID 158
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFD 602
+ R+ F I L+ F GV + + ++++ E G D
Sbjct: 124 AKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLID 158
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFD 602
+ R+ F I L+ F GV + + ++++ E G D
Sbjct: 124 AKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLID 158
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFD 602
+ R+ F I L+ F GV + + ++++ E G D
Sbjct: 124 AKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLID 158
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/198 (25%), Positives = 83/198 (41%), Gaps = 5/198 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVD---ILL 644
+ R+ F I L+ F GV + + ++++ E G D +D L
Sbjct: 125 KQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLS 175
Query: 645 ETAMGITKTTQDAASFDY 698
T + + FDY
Sbjct: 176 RTVSNVISSIVFGDRFDY 193
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 51.2 bits (117), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 4/185 (2%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
+YG V GP+ VV L + V+ L Q + WL G G+ S+GE+
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGER 123
Query: 471 WRSHRKM-IAPTFHINILK-SFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILL 644
+ R+ IA + K E + +++ LR G D ++S +++
Sbjct: 124 AKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIEALRGTHGANIDPTFFLSRTVSNVIS 183
Query: 645 ETAMG 659
G
Sbjct: 184 SIVFG 188
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 2 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 55
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 56 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 112
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 113 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 172
Query: 639 L 641
+
Sbjct: 173 I 173
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 2 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 55
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 56 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 112
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 113 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 172
Query: 639 L 641
+
Sbjct: 173 I 173
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/166 (27%), Positives = 77/166 (46%), Gaps = 9/166 (5%)
Frame = +3
Query: 189 GNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV 368
G PGP L ++GN LL+ ++D++ S++YG++ GP+ VV L+ V
Sbjct: 28 GKLPPGPRPLSILGNLLLLC---SQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAV 84
Query: 369 -EVILNSQIHIDKSPEY-RFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSF-MGV 539
E +++ +Y FF G G+ SSG++W+ R+ F I IL++F MG
Sbjct: 85 KEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGK 139
Query: 540 FN------ENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMG 659
+ E ++ +R G+ FD +S +I+ G
Sbjct: 140 RSIEERILEEGSFLLADVRKTEGEPFDPTFVLSRSVSNIICSVLFG 185
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 4 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 57
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 58 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 114
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 115 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 174
Query: 639 L 641
+
Sbjct: 175 I 175
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 50.8 bits (116), Expect = 5e-06
Identities = 43/181 (23%), Positives = 79/181 (43%), Gaps = 4/181 (2%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + M + W+QS R +L PGP LP++GN L I +D+ K ++
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVE--VILNSQIHIDKSPEYRFFKPWLGEGLLISSG 464
S+ YG V + G +V V+ +I N + + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
++W+ R+ T + +S E + +V++LR D + C ++
Sbjct: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/181 (25%), Positives = 84/181 (46%), Gaps = 7/181 (3%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+KW+ R+ T + +S E ++ +V++LR D + C ++
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 4/178 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWGQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVIL--NSQIHIDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V + G K +V L V+ L + + + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFFGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ R+ T + +S E ++ +V++LR D + C +++
Sbjct: 121 KEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVI 178
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 50.4 bits (115), Expect = 7e-06
Identities = 44/181 (24%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + M + W+QS R +L PGP LP++GN L I +D+ K ++
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 291 SEKYGTVVRAWAG--PKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSG 464
S+ YG V + G P +V +A +I N + + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
++W+ R+ T + +S E + +V++LR D + C ++
Sbjct: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 50.4 bits (115), Expect = 7e-06
Identities = 44/181 (24%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + M + W+QS R +L PGP LP++GN L I +D+ K ++
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 291 SEKYGTVVRAWAG--PKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSG 464
S+ YG V + G P +V +A +I N + + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
++W+ R+ T + +S E + +V++LR D + C ++
Sbjct: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 50.4 bits (115), Expect = 7e-06
Identities = 44/181 (24%), Positives = 80/181 (44%), Gaps = 4/181 (2%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + M + W+QS R +L PGP LP++GN L I +D+ K ++
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 291 SEKYGTVVRAWAG--PKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSG 464
S+ YG V + G P +V +A +I N + + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
++W+ R+ T + +S E + +V++LR D + C ++
Sbjct: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 50.0 bits (114), Expect = 1e-05
Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 4/184 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL + +M ++ WQQ +L PGP LP +GN L + E + + SE+
Sbjct: 11 LLACLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLMKISER 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G++ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERA 124
Query: 474 RS-HRKMIAPTFHINILK-SFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLE 647
+ R IA + K E S +++ +RS G D ++S +++
Sbjct: 125 KQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISS 184
Query: 648 TAMG 659
G
Sbjct: 185 IVFG 188
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 50.0 bits (114), Expect = 1e-05
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 7/164 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVG 590
+KW+ R+ T + +S E ++ +V++LR G
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDCVQEEARCLVEELRKTKG 161
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 49.2 bits (112), Expect = 2e-05
Identities = 50/185 (27%), Positives = 80/185 (43%), Gaps = 5/185 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL + +M ++ WQQ R R G PGP LP +GN L + E + + +SE
Sbjct: 11 LLACLTVMVLMSVWQQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEHICDSIMKFSEC 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWL--GEGLLISSGEK 470
YG V GP+ VV L + V E +++ E F+ W+ G G+ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFE-WVFKGYGVAFSNGER 123
Query: 471 WRS-HRKMIAPTFHINILK-SFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILL 644
+ R IA + K E S +++ +RS G D ++S +++
Sbjct: 124 AKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVIS 183
Query: 645 ETAMG 659
G
Sbjct: 184 SIVFG 188
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 49.2 bits (112), Expect = 2e-05
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 7/164 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + + +L W+QSS +L PGP LP++GN +L +G K D+ K + S+
Sbjct: 7 LVLCLSCLLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSG 464
YG V + G K +V L + E + + I + + R P G G++ S+G
Sbjct: 61 YGPVFTLYFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVG 590
+KW+ R+ T + +S E ++ +V++LR G
Sbjct: 118 KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKG 161
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/184 (26%), Positives = 77/184 (41%), Gaps = 4/184 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL + +M ++ WQQ R R G PGP LP +GN L + E + + +SE
Sbjct: 11 LLACLTVMVLMSVWQQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEHICDSIMKFSEC 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ VV L + V L Q + + F + G G+ S+GE+
Sbjct: 65 YGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERA 124
Query: 474 RS-HRKMIAPTFHINILK-SFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLE 647
+ R IA + K E S +++ +RS G D ++S +++
Sbjct: 125 KQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSSHGANIDPTFFLSRTVSNVISS 184
Query: 648 TAMG 659
G
Sbjct: 185 IVFG 188
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 48.8 bits (111), Expect = 2e-05
Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEVIL 380
PGP LPLVGN L +L +D + ++ SE+YG V G + V LT V+ L
Sbjct: 33 PGPRPLPLVGN-LHLLRLSQQD--RSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEAL 89
Query: 381 NS--QIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAPTFH 509
Q D+ P F G G+ SSG +WR+ R+ H
Sbjct: 90 AGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALH 134
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 48.4 bits (110), Expect = 3e-05
Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 4/177 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
L+L + +++L W+QSS RL + GP LP++GN IL +D+ K ++S+
Sbjct: 7 LVLCLSCLFLLSLWRQSSGRGRLPS---GPTPLPIIGN---ILQLDVKDMSKSLTNFSKV 60
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFF-KPWLGEGLLISSGEKW 473
YG V + G K +V L V E +++ + K G G+L S+G++W
Sbjct: 61 YGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRW 120
Query: 474 RSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
+ + T + +S E ++ +V++LR D + C ++
Sbjct: 121 KEIWRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNV 177
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 7/174 (4%)
Frame = +3
Query: 141 MWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRA 320
M +L W+QSS +L PGP LP++GN +L +G K D+ K + S+ YG V
Sbjct: 1 MLLLSLWRQSSGRGKLP---PGPTPLPVIGN-ILQIGIK--DISKSLTNLSKVYGPVFTL 54
Query: 321 WAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLISSGEKWRSHR 485
+ G K +V L + E + + I + + R P G G++ S+G+KW+ R
Sbjct: 55 YFGLKPIVVL---HGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 111
Query: 486 KMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ T + +S E ++ +V++LR D + C +++
Sbjct: 112 RFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVI 165
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 7/184 (3%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + + +L W+QSS +L PGP LP++GN L I +D+ K +
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQI---DIKDVSKSLTNL 57
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLI 455
S+ YG V + G + +V L + EV+ + I + + R P G G++
Sbjct: 58 SKIYGPVFTLYFGLERMVVL---HGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVF 114
Query: 456 SSGEKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVT 629
S+G++W+ R+ T + +S E ++ +V++LR D + C
Sbjct: 115 SNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAP 174
Query: 630 VDIL 641
+++
Sbjct: 175 CNVI 178
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/181 (23%), Positives = 79/181 (43%), Gaps = 4/181 (2%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + M + W+QS R +L PGP LP++GN L I +D+ K ++
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 291 SEKYGTVVRAWAG--PKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSG 464
S+ YG V + G P +V +A +I N + + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
++W+ R+ + +S E + +V++LR D + C ++
Sbjct: 118 KRWKEIRRFSLTNLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/181 (23%), Positives = 79/181 (43%), Gaps = 4/181 (2%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + M + W+QS R +L PGP LP++GN L I +D+ K ++
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNF 57
Query: 291 SEKYGTVVRAWAG--PKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSG 464
S+ YG V + G P +V +A +I N + + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 465 EKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDI 638
++W+ R+ + +S E + +V++LR D + C ++
Sbjct: 118 KRWKEIRRFSLTNLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177
Query: 639 L 641
+
Sbjct: 178 I 178
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 7/184 (3%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + + +L W+QSS +L PGP LP++GN L I +D+ K +
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQI---DIKDVSKSLTNL 57
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLI 455
S+ YG V + G + +V L + EV+ + I + + R P G G++
Sbjct: 58 SKIYGPVFTLYFGLERMVVL---HGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVF 114
Query: 456 SSGEKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVT 629
S+G++W+ R+ T + +S E ++ +V++LR D + C
Sbjct: 115 SNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAP 174
Query: 630 VDIL 641
+++
Sbjct: 175 CNVI 178
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 7/184 (3%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + + +L W+QSS +L PGP LP++GN L I +D+ K +
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQI---DIKDVSKSLTNL 57
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLI 455
S+ YG V + G + +V L + EV+ + I + + R P G G++
Sbjct: 58 SKIYGPVFTLYFGLERMVVL---HGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVF 114
Query: 456 SSGEKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVT 629
S+G++W+ R+ T + +S E ++ +V++LR D + C
Sbjct: 115 SNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAP 174
Query: 630 VDIL 641
+++
Sbjct: 175 CNVI 178
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 48.4 bits (110), Expect = 3e-05
Identities = 46/184 (25%), Positives = 84/184 (45%), Gaps = 7/184 (3%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + + +L W+QSS +L PGP LP++GN L I +D+ K +
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQI---DIKDVSKSLTNL 57
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLI 455
S+ YG V + G + +V L + EV+ + I + + R P G G++
Sbjct: 58 SKIYGPVFTLYFGLERMVVL---HGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVF 114
Query: 456 SSGEKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVT 629
S+G++W+ R+ T + +S E ++ +V++LR D + C
Sbjct: 115 SNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAP 174
Query: 630 VDIL 641
+++
Sbjct: 175 CNVI 178
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 47.2 bits (107), Expect = 7e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 5/192 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LLLA+ ++ +L +R G+ PGP LPL+GN L + + L + S+K
Sbjct: 9 LLLALALLLLLTLALSGTRA--RGHLPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKK 63
Query: 300 YGTVVRAWAGP-KLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEK 470
YG V + GP + VV L V L Q + + G G+ S+GE+
Sbjct: 64 YGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMG--VFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILL 644
WR RK + G + ++ +V+ + G+ FD ++ T +++
Sbjct: 124 WRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVC 183
Query: 645 ETAMGITKTTQD 680
G+ + +D
Sbjct: 184 SLLFGLRFSYED 195
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 47.2 bits (107), Expect = 7e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 5/192 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LLLA+ ++ +L +R G+ PGP LPL+GN L + + L + S+K
Sbjct: 9 LLLALALLLLLTLALSGTRA--RGHLPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKK 63
Query: 300 YGTVVRAWAGP-KLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEK 470
YG V + GP + VV L V L Q + + G G+ S+GE+
Sbjct: 64 YGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMG--VFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILL 644
WR RK + G + ++ +V+ + G+ FD ++ T +++
Sbjct: 124 WRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVC 183
Query: 645 ETAMGITKTTQD 680
G+ + +D
Sbjct: 184 SLLFGLRFSYED 195
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 47.2 bits (107), Expect = 7e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 5/192 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LLLA+ ++ +L +R G+ PGP LPL+GN L + + L + S+K
Sbjct: 9 LLLALALLLLLTLALSGTRA--RGHLPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKK 63
Query: 300 YGTVVRAWAGP-KLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEK 470
YG V + GP + VV L V L Q + + G G+ S+GE+
Sbjct: 64 YGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMG--VFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILL 644
WR RK + G + ++ +V+ + G+ FD ++ T +++
Sbjct: 124 WRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVC 183
Query: 645 ETAMGITKTTQD 680
G+ + +D
Sbjct: 184 SLLFGLRFSYED 195
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 47.2 bits (107), Expect = 7e-05
Identities = 47/192 (24%), Positives = 81/192 (42%), Gaps = 5/192 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LLLA+ ++ +L +R G+ PGP LPL+GN L + + L + S+K
Sbjct: 9 LLLALALLLLLTLALSGTRA--RGHLPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKK 63
Query: 300 YGTVVRAWAGP-KLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEK 470
YG V + GP + VV L V L Q + + G G+ S+GE+
Sbjct: 64 YGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGER 123
Query: 471 WRSHRKMIAPTFHINILKSFMG--VFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILL 644
WR RK + G + ++ +V+ + G+ FD ++ T +++
Sbjct: 124 WRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVC 183
Query: 645 ETAMGITKTTQD 680
G+ + +D
Sbjct: 184 SLLFGLRFSYED 195
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 46.8 bits (106), Expect = 9e-05
Identities = 48/184 (26%), Positives = 76/184 (41%), Gaps = 4/184 (2%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL + +M ++ WQQ R R G PGP LP +GN L + E + + +SE
Sbjct: 11 LLACLTVMVLMSVWQQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEHICDSIMKFSEC 64
Query: 300 YGTVVRAWAGPKLVVFLTDANDVEVILNSQIH--IDKSPEYRFFKPWLGEGLLISSGEKW 473
YG V GP+ V L + V L Q + + F + G G+ S+GE+
Sbjct: 65 YGPVFTIHLGPRRAVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERA 124
Query: 474 RS-HRKMIAPTFHINILK-SFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLE 647
+ R IA + K E S +++ +RS G D ++S +++
Sbjct: 125 KQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISS 184
Query: 648 TAMG 659
G
Sbjct: 185 IVFG 188
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/176 (24%), Positives = 80/176 (45%), Gaps = 4/176 (2%)
Frame = +3
Query: 126 LAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYG 305
L+ M+++ L W+QS R +L PGP LP++GN L I +D+ K ++S+ YG
Sbjct: 1 LSFMLLFSL--WRQSCRRRKLP---PGPTPLPIIGNMLQI---DVKDICKSFTNFSKVYG 52
Query: 306 TVVRAWAG--PKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRS 479
V + G P +V +A +I N + + + G G++ S+G++W+
Sbjct: 53 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKE 112
Query: 480 HRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
R+ T + +S E + +V++LR D + C +++
Sbjct: 113 IRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVI 168
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +3
Query: 192 NKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE 371
N PGP LP +GN L+ +++ V+ + +KYG + G V +T +
Sbjct: 42 NYPPGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLIT---GLP 95
Query: 372 VILNSQIHIDKSPEYRFFKP-----WLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSF 530
+I + IH+D++ R P + GL++SSG+ W+ R+ L KS
Sbjct: 96 LIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSL 155
Query: 531 MGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDA 683
E ++ + + ++ E G+ FD H ++ +I+ G QD+
Sbjct: 156 EERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDS 206
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +3
Query: 192 NKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE 371
N PGP LP +GN L+ +++ V+ + +KYG + G V +T +
Sbjct: 42 NYPPGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLIT---GLP 95
Query: 372 VILNSQIHIDKSPEYRFFKP-----WLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSF 530
+I + IH+D++ R P + GL++SSG+ W+ R+ L KS
Sbjct: 96 LIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSL 155
Query: 531 MGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDA 683
E ++ + + ++ E G+ FD H ++ +I+ G QD+
Sbjct: 156 EERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDS 206
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +3
Query: 192 NKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE 371
N PGP LP +GN L+ +++ V+ + +KYG + G V +T +
Sbjct: 42 NYPPGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLIT---GLP 95
Query: 372 VILNSQIHIDKSPEYRFFKP-----WLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSF 530
+I + IH+D++ R P + GL++SSG+ W+ R+ L KS
Sbjct: 96 LIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSL 155
Query: 531 MGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDA 683
E ++ + + ++ E G+ FD H ++ +I+ G QD+
Sbjct: 156 EERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDS 206
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +3
Query: 192 NKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE 371
N PGP LP +GN L+ +++ V+ + +KYG + G V +T +
Sbjct: 42 NYPPGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLIT---GLP 95
Query: 372 VILNSQIHIDKSPEYRFFKP-----WLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSF 530
+I + IH+D++ R P + GL++SSG+ W+ R+ L KS
Sbjct: 96 LIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSL 155
Query: 531 MGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDA 683
E ++ + + ++ E G+ FD H ++ +I+ G QD+
Sbjct: 156 EERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDS 206
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 7/171 (4%)
Frame = +3
Query: 192 NKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE 371
N PGP LP +GN L+ +++ V+ + +KYG + G V +T +
Sbjct: 42 NYPPGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLIT---GLP 95
Query: 372 VILNSQIHIDKSPEYRFFKP-----WLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSF 530
+I + IH+D++ R P + GL++SSG+ W+ R+ L KS
Sbjct: 96 LIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSL 155
Query: 531 MGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDA 683
E ++ + + ++ E G+ FD H ++ +I+ G QD+
Sbjct: 156 EERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDS 206
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 7/163 (4%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
F L+L + + +L W+QSS +L PGP LP++GN L I +D+ K +
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQI---DIKDVSKSLTNL 57
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKPWL-----GEGLLI 455
S+ YG V + G + +V L + EV+ + I + + R P G G++
Sbjct: 58 SKIYGPVFTLYFGLERMVVL---HGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVF 114
Query: 456 SSGEKWRSHRKMIAPTFHINIL--KSFMGVFNENSKSVVKKLR 578
S+G++W+ R+ T + +S E ++ +V++LR
Sbjct: 115 SNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELR 157
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 327 GPKLVVFLTDANDVEVILNSQIHIDKSPEYRFFKP--WLGEGLLISSGEKWRSHRKMIAP 500
G + V+ +TD + ++ +L + + R F P ++ + I+ E+W+ R +++P
Sbjct: 4 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 62
Query: 501 TFHINILKSFMGVFNENSKSVVKKLR--SEVGKTFDVHDYMSCVTVDILLETAMGI 662
TF LK + + + +V+ LR +E GK + D ++D++ T+ G+
Sbjct: 63 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 118
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/91 (34%), Positives = 44/91 (48%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
TLL + +M ++ W+Q R R G PGP LP +GN L + E + + SE
Sbjct: 10 TLLACLTVMVLMSVWRQ--RKSR-GKLPPGPTPLPFIGNYLQL---NTEQMYNSLMKISE 63
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVILNSQ 389
+YG V GP+ VV L + V+ L Q
Sbjct: 64 RYGPVFTIHLGPRRVVVLCGHDAVKEALVDQ 94
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 44.4 bits (100), Expect = 5e-04
Identities = 41/171 (23%), Positives = 75/171 (43%), Gaps = 7/171 (4%)
Frame = +3
Query: 192 NKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE 371
N PGP LP +GN L+ +++ V+ + +KYG + G V +T +
Sbjct: 11 NYPPGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLIT---GLP 64
Query: 372 VILNSQIHIDKSPEYRFFKP-----WLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSF 530
+I + IH+D++ R P + GL++SSG+ W+ R+ L K
Sbjct: 65 LIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKGL 124
Query: 531 MGVFNENSKSVVKKLRSEVGKTFDVHDYMSCVTVDILLETAMGITKTTQDA 683
E ++ + + ++ E G+ FD H ++ +I+ G QD+
Sbjct: 125 EERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDS 175
>AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family 46
variant protein.
Length = 210
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Frame = +3
Query: 438 GEGLLISSG-EKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEV-GKT-FDVH 608
G+GL+ E+W R++I F + L S M FNE ++ +V+ L ++ G+T +
Sbjct: 93 GQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQ 152
Query: 609 DYMSCVTVDILLETAMGITKTTQDAASFDYAMAVMKM 719
D ++ +DIL + A G+ + A + AV M
Sbjct: 153 DMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLM 189
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 40.3 bits (90), Expect = 0.008
Identities = 54/198 (27%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Frame = +3
Query: 198 LPGPMALPLVGNSLLILGKKA-EDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEV 374
LPGP + PL+G+ L IL K + ++Y +KYG + R G V L +E
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 375 ILNSQIHIDKSPEYRFFKPWL--------GEGLLISSGEKWRS-----HRKMIAP----- 500
+ ++ P+ KPW G GLLI GE W+ +K++ P
Sbjct: 118 LYRTE---SAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMK 174
Query: 501 -TFHIN-ILKSFMGVFNE--NSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 665
IN +L FMG +E + + V+ L SE+ K +F+ C+ +L E G+
Sbjct: 175 LDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFE----SICL---VLYEKRFGLL 227
Query: 666 KTTQDAASFDYAMAVMKM 719
+ + ++ MA+ M
Sbjct: 228 QKNAGDEAVNFIMAIKTM 245
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 40.3 bits (90), Expect = 0.008
Identities = 54/198 (27%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Frame = +3
Query: 198 LPGPMALPLVGNSLLILGKKA-EDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEV 374
LPGP + PL+G+ L IL K + ++Y +KYG + R G V L +E
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 375 ILNSQIHIDKSPEYRFFKPWL--------GEGLLISSGEKWRS-----HRKMIAP----- 500
+ ++ P+ KPW G GLLI GE W+ +K++ P
Sbjct: 118 LYRTE---SAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMK 174
Query: 501 -TFHIN-ILKSFMGVFNE--NSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 665
IN +L FMG +E + + V+ L SE+ K +F+ C+ +L E G+
Sbjct: 175 LDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFE----SICL---VLYEKRFGLL 227
Query: 666 KTTQDAASFDYAMAVMKM 719
+ + ++ MA+ M
Sbjct: 228 QKNAGDEAVNFIMAIKTM 245
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 40.3 bits (90), Expect = 0.008
Identities = 54/198 (27%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Frame = +3
Query: 198 LPGPMALPLVGNSLLILGKKA-EDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEV 374
LPGP + PL+G+ L IL K + ++Y +KYG + R G V L +E
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 375 ILNSQIHIDKSPEYRFFKPWL--------GEGLLISSGEKWRS-----HRKMIAP----- 500
+ ++ P+ KPW G GLLI GE W+ +K++ P
Sbjct: 118 LYRTE---SAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMK 174
Query: 501 -TFHIN-ILKSFMGVFNE--NSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 665
IN +L FMG +E + + V+ L SE+ K +F+ C+ +L E G+
Sbjct: 175 LDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFE----SICL---VLYEKRFGLL 227
Query: 666 KTTQDAASFDYAMAVMKM 719
+ + ++ MA+ M
Sbjct: 228 QKNAGDEAVNFIMAIKTM 245
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 40.3 bits (90), Expect = 0.008
Identities = 54/198 (27%), Positives = 87/198 (43%), Gaps = 24/198 (12%)
Frame = +3
Query: 198 LPGPMALPLVGNSLLILGKKA-EDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEV 374
LPGP + PL+G+ L IL K + ++Y +KYG + R G V L +E
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 375 ILNSQIHIDKSPEYRFFKPWL--------GEGLLISSGEKWRS-----HRKMIAP----- 500
+ ++ P+ KPW G GLLI GE W+ +K++ P
Sbjct: 118 LYRTE---SAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMK 174
Query: 501 -TFHIN-ILKSFMGVFNE--NSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 665
IN +L FMG +E + + V+ L SE+ K +F+ C+ +L E G+
Sbjct: 175 LDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFE----SICL---VLYEKRFGLL 227
Query: 666 KTTQDAASFDYAMAVMKM 719
+ + ++ MA+ M
Sbjct: 228 QKNAGDEAVNFIMAIKTM 245
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/151 (23%), Positives = 65/151 (43%), Gaps = 4/151 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAG--PKLVVFLTDANDVEV 374
PGP LP++GN L I +D+ K ++S+ YG V + G P +V +A +
Sbjct: 3 PGPTPLPIIGNMLQI---DVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEAL 59
Query: 375 ILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINIL--KSFMGVFNE 548
I N + + + G G++ S+G++W+ R+ T + +S E
Sbjct: 60 IDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQE 119
Query: 549 NSKSVVKKLRSEVGKTFDVHDYMSCVTVDIL 641
+ +V +LR D + C +++
Sbjct: 120 EAHCLVDELRKTKASPCDPTFILGCAPCNVI 150
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPAWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 38.3 bits (85), Expect = 0.031
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLF-RLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSE 296
LLLA+ ++ + ++ LF RLG +PGP LPL+GN L + L K+ + +
Sbjct: 13 LLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVL----SYRQGLWKFDTECYK 66
Query: 297 KYGTVVRAWAGPKLVVFLTDANDVEVIL 380
KYG + + G V+ +TD + + +L
Sbjct: 67 KYGKMWGTYEGQLPVLAITDPDVIRTVL 94
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 38.3 bits (85), Expect = 0.031
Identities = 36/184 (19%), Positives = 81/184 (44%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V + G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 37.9 bits (84), Expect = 0.041
Identities = 53/198 (26%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Frame = +3
Query: 198 LPGPMALPLVGNSLLILGKKA-EDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEV 374
LPGP + PL+ + L IL K + ++Y +KYG + R G V L
Sbjct: 58 LPGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGS----PC 113
Query: 375 ILNSQIHIDKSPEYRFFKPWL--------GEGLLISSGEKWRS-----HRKMIAP----- 500
+L + + P+ KPW G GLLI GE W+ +K++ P
Sbjct: 114 LLEALYRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMK 173
Query: 501 -TFHIN-ILKSFMGVFNE--NSKSVVKKLRSEVGK-TFDVHDYMSCVTVDILLETAMGIT 665
IN +L FMG +E + + V+ L SE+ K +F+ C+ +L E G+
Sbjct: 174 LDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFE----SICL---VLYEKRFGLL 226
Query: 666 KTTQDAASFDYAMAVMKM 719
+ + ++ MA+ M
Sbjct: 227 QKNAGDEAVNFIMAIKTM 244
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 37.5 bits (83), Expect = 0.055
Identities = 39/139 (28%), Positives = 57/139 (41%), Gaps = 5/139 (3%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE--V 374
PGP LP +GN + L +E Y S+ YG + G V L + V+ +
Sbjct: 41 PGPPGLPFIGN-IYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECL 99
Query: 375 ILNSQIHIDKSPEYRFFKPWLGEGLLISS-GEKWRSHRKMIAPTFHI--NILKSFMGVFN 545
+ S+I D+ F K GLL S G W HR++ +F KSF
Sbjct: 100 VHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKIL 159
Query: 546 ENSKSVVKKLRSEVGKTFD 602
E +K + + G+ FD
Sbjct: 160 EETKFFNDAIETYKGRPFD 178
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 37.5 bits (83), Expect = 0.055
Identities = 39/139 (28%), Positives = 57/139 (41%), Gaps = 5/139 (3%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE--V 374
PGP LP +GN + L +E Y S+ YG + G V L + V+ +
Sbjct: 41 PGPPGLPFIGN-IYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECL 99
Query: 375 ILNSQIHIDKSPEYRFFKPWLGEGLLISS-GEKWRSHRKMIAPTFHI--NILKSFMGVFN 545
+ S+I D+ F K GLL S G W HR++ +F KSF
Sbjct: 100 VHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKIL 159
Query: 546 ENSKSVVKKLRSEVGKTFD 602
E +K + + G+ FD
Sbjct: 160 EETKFFNDAIETYKGRPFD 178
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 37.5 bits (83), Expect = 0.055
Identities = 39/139 (28%), Positives = 57/139 (41%), Gaps = 5/139 (3%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE--V 374
PGP LP +GN + L +E Y S+ YG + G V L + V+ +
Sbjct: 41 PGPPGLPFIGN-IYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECL 99
Query: 375 ILNSQIHIDKSPEYRFFKPWLGEGLLISS-GEKWRSHRKMIAPTFHI--NILKSFMGVFN 545
+ S+I D+ F K GLL S G W HR++ +F KSF
Sbjct: 100 VHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKIL 159
Query: 546 ENSKSVVKKLRSEVGKTFD 602
E +K + + G+ FD
Sbjct: 160 EETKFFNDAIETYKGRPFD 178
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 36.7 bits (81), Expect = 0.095
Identities = 36/184 (19%), Positives = 80/184 (43%), Gaps = 8/184 (4%)
Frame = +3
Query: 120 LLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDYSEK 299
LL+ + ++ W+Q + L PGP LP++GN + + +++ K +++
Sbjct: 10 LLVWAAFLLLVSMWRQVHSSWNLP---PGPFPLPIIGN---LFQLELKNIPKSFTRLAQR 63
Query: 300 YGTVVRAWAGPKLVVFLTDANDV-EVILNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWR 476
+G V G + +V + V E +L+ + + F G++ ++G W+
Sbjct: 64 FGPVFTLCVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWK 123
Query: 477 SHRKMIAPTFHINILKSF-MGVFNENSK------SVVKKLRSEVGKTFDVHDYMSCVTVD 635
R+ F + L+++ MG S+ +++ LR G+ FD + C +
Sbjct: 124 DIRR-----FSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCN 178
Query: 636 ILLE 647
++ +
Sbjct: 179 VIAD 182
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 36.7 bits (81), Expect = 0.095
Identities = 31/157 (19%), Positives = 70/157 (44%), Gaps = 8/157 (5%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDV-EVI 377
PGP LP++GN + + +++ K ++++G V + G + +V + V E +
Sbjct: 3 PGPFPLPIIGN---LFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEAL 59
Query: 378 LNSQIHIDKSPEYRFFKPWLGEGLLISSGEKWRSHRKMIAPTFHINILKSF-MGVFNENS 554
L+ + + F G++ ++G W+ R+ F + L+++ MG S
Sbjct: 60 LDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRR-----FSLTTLRNYGMGKQGNES 114
Query: 555 K------SVVKKLRSEVGKTFDVHDYMSCVTVDILLE 647
+ +++ LR G+ FD + C +++ +
Sbjct: 115 RIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIAD 151
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase
protein.
Length = 371
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSK 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSK 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSK 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSK 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSK 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 44 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 103
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 104 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 163
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 164 EFSLLTCSIICYLTFG 179
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 35.5 bits (78), Expect = 0.22
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFRERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 35.5 bits (78), Expect = 0.22
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVEEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSLLTCSIICYLTFG 178
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 35.5 bits (78), Expect = 0.22
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 4/136 (2%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSR 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDILLETAMG 659
S +T I+ G
Sbjct: 163 EFSPLTCSIICYLTFG 178
>AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein.
Length = 112
Score = 35.5 bits (78), Expect = 0.22
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +3
Query: 117 TLLLAIMIMWMLHRWQQSSRLFR--LGNKLPGPMALPLVGNSLLILGKKAEDLVKYALDY 290
TLLL + ++ +H Q+ R R LG+ PGP A PL+GN+ + G+ A + +A
Sbjct: 22 TLLLLLSVLATVHVGQRLLRQRRRQLGSAPPGPFAWPLIGNAAAV-GQAAH--LSFA-RL 77
Query: 291 SEKYGTVVRAWAGPKLVVFLTDANDVEVILNSQ 389
+ +YG V + G +V L + L Q
Sbjct: 78 ARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQ 110
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 35.1 bits (77), Expect = 0.29
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Frame = +3
Query: 282 LDYSEKYGTVVRAWAGPKLVVFLTDANDVEVILNS--QIHIDKSPEYRFFKPWLGEGLLI 455
++ SE+YG V G + V LT V+ L Q D+ P F G G+
Sbjct: 1 MELSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFF 60
Query: 456 SSGEKWRSHRKMIAPTFH 509
SSG +WR+ R+ H
Sbjct: 61 SSGARWRAARQFTVRALH 78
>X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase
protein.
Length = 371
Score = 34.7 bits (76), Expect = 0.38
Identities = 28/129 (21%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE +K
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSK 102
Query: 441 EGLLISSGEK---WRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHD 611
+S G+ W++H+K+ + I S V + ++ +++R++ G + +
Sbjct: 103 NYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEE 162
Query: 612 YMSCVTVDI 638
S +T I
Sbjct: 163 EFSLLTCSI 171
>X58907-1|CAA41710.1| 369|Homo sapiens steroid 21-monooxygenase
protein.
Length = 369
Score = 34.3 bits (75), Expect = 0.51
Identities = 27/133 (20%), Positives = 52/133 (39%), Gaps = 1/133 (0%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE L
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTTSWCLR 102
Query: 441 EGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMS 620
W++H+K+ + I S V + ++ +++R++ G + + S
Sbjct: 103 TTRTCRWSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFS 162
Query: 621 CVTVDILLETAMG 659
+T I+ G
Sbjct: 163 LLTCSIICYLTFG 175
>X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase
protein.
Length = 368
Score = 34.3 bits (75), Expect = 0.51
Identities = 27/133 (20%), Positives = 52/133 (39%), Gaps = 1/133 (0%)
Frame = +3
Query: 264 DLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVE-VILNSQIHIDKSPEYRFFKPWLG 440
DL Y L ++K+G + R G + VV L +E ++ PE L
Sbjct: 43 DLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTSSWCLR 102
Query: 441 EGLLISSGEKWRSHRKMIAPTFHINILKSFMGVFNENSKSVVKKLRSEVGKTFDVHDYMS 620
W++H+K+ + I S V + ++ +++R++ G + + S
Sbjct: 103 TTRTCRWSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFS 162
Query: 621 CVTVDILLETAMG 659
+T I+ G
Sbjct: 163 LLTCSIICYLTFG 175
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 34.3 bits (75), Expect = 0.51
Identities = 18/45 (40%), Positives = 25/45 (55%)
Frame = +3
Query: 111 FHTLLLAIMIMWMLHRWQQSSRLFRLGNKLPGPMALPLVGNSLLI 245
F L+L + M + W+QS R +L PGP LP++GN L I
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI 45
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 32.7 bits (71), Expect = 1.6
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEVIL 380
PGP PL+G+ +L LGK + S++YG V++ G VV L+ + + L
Sbjct: 41 PGPWGWPLIGH-MLTLGKNPHLALS---RMSQQYGDVLQIRIGSTPVVVLSGLDTIRQAL 96
Query: 381 NSQIHIDKS-PE-YRFFKPWLGEGLLIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNE 548
Q K P+ Y F G+ + S SG W + R++ N LKSF + ++
Sbjct: 97 VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIASD 150
Query: 549 NSKSVVKKLRSEVGKTFDV 605
+ S L V K +V
Sbjct: 151 PASSTSCYLEEHVSKEAEV 169
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 32.7 bits (71), Expect = 1.6
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEVIL 380
PGP PL+G+ +L LGK + S++YG V++ G VV L+ + + L
Sbjct: 41 PGPWGWPLIGH-MLTLGKNPHLALS---RMSQQYGDVLQIRIGSTPVVVLSGLDTIRQAL 96
Query: 381 NSQIHIDKS-PE-YRFFKPWLGEGLLIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNE 548
Q K P+ Y F G+ + S SG W + R++ N LKSF + ++
Sbjct: 97 VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIASD 150
Query: 549 NSKSVVKKLRSEVGKTFDV 605
+ S L V K +V
Sbjct: 151 PASSTSCYLEEHVSKEAEV 169
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 32.7 bits (71), Expect = 1.6
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEVIL 380
PGP PL+G+ +L LGK + S++YG V++ G VV L+ + + L
Sbjct: 41 PGPWGWPLIGH-MLTLGKNPHLALS---RMSQQYGDVLQIRIGSTPVVVLSGLDTIRQAL 96
Query: 381 NSQIHIDKS-PE-YRFFKPWLGEGLLIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNE 548
Q K P+ Y F G+ + S SG W + R++ N LKSF + ++
Sbjct: 97 VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIASD 150
Query: 549 NSKSVVKKLRSEVGKTFDV 605
+ S L V K +V
Sbjct: 151 PASSTSCYLEEHVSKEAEV 169
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 32.7 bits (71), Expect = 1.6
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEVIL 380
PGP PL+G+ +L LGK + S++YG V++ G VV L+ + + L
Sbjct: 41 PGPWGWPLIGH-MLTLGKNPHLALS---RMSQQYGDVLQIRIGSTPVVVLSGLDTIRQAL 96
Query: 381 NSQIHIDKS-PE-YRFFKPWLGEGLLIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNE 548
Q K P+ Y F G+ + S SG W + R++ N LKSF + ++
Sbjct: 97 VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIASD 150
Query: 549 NSKSVVKKLRSEVGKTFDV 605
+ S L V K +V
Sbjct: 151 PASSTSCYLEEHVSKEAEV 169
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 32.7 bits (71), Expect = 1.6
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Frame = +3
Query: 201 PGPMALPLVGNSLLILGKKAEDLVKYALDYSEKYGTVVRAWAGPKLVVFLTDANDVEVIL 380
PGP PL+G+ +L LGK + S++YG V++ G VV L+ + + L
Sbjct: 41 PGPWGWPLIGH-MLTLGKNPHLALS---RMSQQYGDVLQIRIGSTPVVVLSGLDTIRQAL 96
Query: 381 NSQIHIDKS-PE-YRFFKPWLGEGLLIS--SGEKWRSHRKMIAPTFHINILKSFMGVFNE 548
Q K P+ Y F G+ + S SG W + R++ N LKSF + ++
Sbjct: 97 VRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIASD 150
Query: 549 NSKSVVKKLRSEVGKTFDV 605
+ S L V K +V
Sbjct: 151 PASSTSCYLEEHVSKEAEV 169
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,424,472
Number of Sequences: 237096
Number of extensions: 2294280
Number of successful extensions: 4869
Number of sequences better than 10.0: 288
Number of HSP's better than 10.0 without gapping: 4460
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4696
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9646050614
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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