Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt1o01
(770 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL445230-5|CAI15008.1| 255|Homo sapiens nicastrin protein. 93 1e-18
D87442-1|BAA13383.1| 708|Homo sapiens KIAA0253 protein. 91 3e-18
BC047621-1|AAH47621.1| 689|Homo sapiens NCSTN protein protein. 91 3e-18
AY359120-1|AAQ89478.1| 709|Homo sapiens ATAG1874 protein. 91 3e-18
AL445230-7|CAI15010.1| 689|Homo sapiens nicastrin protein. 91 3e-18
AL445230-6|CAI15009.1| 709|Homo sapiens nicastrin protein. 91 3e-18
AF240468-1|AAG11412.1| 709|Homo sapiens nicastrin protein. 91 3e-18
AL445230-4|CAI15007.1| 232|Homo sapiens nicastrin protein. 91 4e-18
AL445230-3|CAI15006.1| 134|Homo sapiens nicastrin protein. 62 2e-09
AJ430032-1|CAD22550.1| 1156|Homo sapiens mucin 4 protein. 32 2.6
AJ400858-1|CAC14143.1| 2167|Homo sapiens MUC4 protein splice var... 32 2.6
AJ400857-1|CAC14142.1| 1827|Homo sapiens MUC4 protein splice var... 32 2.6
AJ277412-1|CAC10061.1| 2117|Homo sapiens mucin 4, variant V3 pro... 32 2.6
AJ276359-1|CAB81773.1| 2169|Homo sapiens mucin 4 protein. 32 2.6
AJ242550-1|CAB85606.1| 1125|Homo sapiens MUC4/X apomucin protein. 32 2.6
AJ242549-1|CAB85605.1| 1176|Homo sapiens MUC4/Y apomucin protein. 32 2.6
AJ242548-1|CAB85604.1| 930|Homo sapiens sv8-MUC4 apomucin protein. 32 2.6
AJ242547-1|CAB85603.1| 814|Homo sapiens sv7-MUC4 apomucin protein. 32 2.6
AJ010901-1|CAB38059.1| 1156|Homo sapiens MUC4 protein. 32 2.6
AF522055-1|AAM66747.1| 2169|Homo sapiens MUC4 protein. 32 2.6
>AL445230-5|CAI15008.1| 255|Homo sapiens nicastrin protein.
Length = 255
Score = 92.7 bits (220), Expect = 1e-18
Identities = 57/182 (31%), Positives = 92/182 (50%), Gaps = 8/182 (4%)
Frame = +1
Query: 235 LLVTIILL--IFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFV 408
LL +LL + +G S ER IY + +A C R LN THQ GC +S G GV+H V
Sbjct: 20 LLSFCVLLAGLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVV 76
Query: 409 QDHDDVLWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTH 582
+ +D+ W+ T+ PYM ++ + F L+E L + IAG+ S F+
Sbjct: 77 EKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSP 136
Query: 583 DTRCPNE----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEKN 750
+CPN+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 137 SVQCPNDGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQ 194
Query: 751 QS 756
++
Sbjct: 195 ET 196
>D87442-1|BAA13383.1| 708|Homo sapiens KIAA0253 protein.
Length = 708
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/179 (31%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Frame = +1
Query: 235 LLVTIILL--IFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFV 408
LL +LL + +G S ER IY + +A C R LN THQ GC +S G GV+H V
Sbjct: 19 LLSFCVLLAGLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVV 75
Query: 409 QDHDDVLWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTH 582
+ +D+ W+ T+ PYM ++ + F L+E L + IAG+ S F+
Sbjct: 76 EKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSP 135
Query: 583 DTRCPNE----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
+CPN+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 136 SVQCPNDGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 192
>BC047621-1|AAH47621.1| 689|Homo sapiens NCSTN protein protein.
Length = 689
Score = 91.5 bits (217), Expect = 3e-18
Identities = 54/173 (31%), Positives = 87/173 (50%), Gaps = 6/173 (3%)
Frame = +1
Query: 247 IILLIFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFVQDHDDV 426
I+ + +G S ER IY + +A C R LN THQ GC +S G GV+H V+ +D+
Sbjct: 6 ILESLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDL 62
Query: 427 LWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTHDTRCPN 600
W+ T+ PYM ++ + F L+E L + IAG+ S F+ +CPN
Sbjct: 63 QWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPN 122
Query: 601 E----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 123 DGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 173
>AY359120-1|AAQ89478.1| 709|Homo sapiens ATAG1874 protein.
Length = 709
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/179 (31%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Frame = +1
Query: 235 LLVTIILL--IFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFV 408
LL +LL + +G S ER IY + +A C R LN THQ GC +S G GV+H V
Sbjct: 20 LLSFCVLLAGLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVV 76
Query: 409 QDHDDVLWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTH 582
+ +D+ W+ T+ PYM ++ + F L+E L + IAG+ S F+
Sbjct: 77 EKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSP 136
Query: 583 DTRCPNE----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
+CPN+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 137 SVQCPNDGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 193
>AL445230-7|CAI15010.1| 689|Homo sapiens nicastrin protein.
Length = 689
Score = 91.5 bits (217), Expect = 3e-18
Identities = 54/173 (31%), Positives = 87/173 (50%), Gaps = 6/173 (3%)
Frame = +1
Query: 247 IILLIFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFVQDHDDV 426
I+ + +G S ER IY + +A C R LN THQ GC +S G GV+H V+ +D+
Sbjct: 6 ILESLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDL 62
Query: 427 LWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTHDTRCPN 600
W+ T+ PYM ++ + F L+E L + IAG+ S F+ +CPN
Sbjct: 63 QWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPN 122
Query: 601 E----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 123 DGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 173
>AL445230-6|CAI15009.1| 709|Homo sapiens nicastrin protein.
Length = 709
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/179 (31%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Frame = +1
Query: 235 LLVTIILL--IFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFV 408
LL +LL + +G S ER IY + +A C R LN THQ GC +S G GV+H V
Sbjct: 20 LLSFCVLLAGLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVV 76
Query: 409 QDHDDVLWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTH 582
+ +D+ W+ T+ PYM ++ + F L+E L + IAG+ S F+
Sbjct: 77 EKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSP 136
Query: 583 DTRCPNE----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
+CPN+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 137 SVQCPNDGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 193
>AF240468-1|AAG11412.1| 709|Homo sapiens nicastrin protein.
Length = 709
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/179 (31%), Positives = 90/179 (50%), Gaps = 8/179 (4%)
Frame = +1
Query: 235 LLVTIILL--IFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFV 408
LL +LL + +G S ER IY + +A C R LN THQ GC +S G GV+H V
Sbjct: 20 LLSFCVLLAGLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVV 76
Query: 409 QDHDDVLWLATNASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTH 582
+ +D+ W+ T+ PYM ++ + F L+E L + IAG+ S F+
Sbjct: 77 EKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSP 136
Query: 583 DTRCPNE----FSSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
+CPN+ +S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 137 SVQCPNDGFGVYSNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 193
>AL445230-4|CAI15007.1| 232|Homo sapiens nicastrin protein.
Length = 232
Score = 91.1 bits (216), Expect = 4e-18
Identities = 53/167 (31%), Positives = 84/167 (50%), Gaps = 6/167 (3%)
Frame = +1
Query: 265 KGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFVQDHDDVLWLATN 444
+G S ER IY + +A C R LN THQ GC +S G GV+H V+ +D+ W+ T+
Sbjct: 65 RGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTD 121
Query: 445 ASAGPYMAVVSTSKF--GLVEFLIDHPTNIAGVLTYENASDIPSFFTHDTRCPNE----F 606
PYM ++ + F L+E L + IAG+ S F+ +CPN+ +
Sbjct: 122 GPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVY 181
Query: 607 SSADGNQCSSSKEGGVVWNEKGTGLLKREIPFPIFFIPESRYEEIEK 747
S++ G + + +E + WN G GL + FPIF + + ++ K
Sbjct: 182 SNSYGPEFAHCRE--IQWNSLGNGLAYEDFSFPIFLLEDENETKVIK 226
>AL445230-3|CAI15006.1| 134|Homo sapiens nicastrin protein.
Length = 134
Score = 62.5 bits (145), Expect = 2e-09
Identities = 33/87 (37%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Frame = +1
Query: 235 LLVTIILL--IFKGYSCERLHELIYSSIEGSAACFRRLNGTHQTGCSTSDKGAVGVVHFV 408
LL +LL + +G S ER IY + +A C R LN THQ GC +S G GV+H V
Sbjct: 20 LLSFCVLLAGLCRGNSVERK---IYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVV 76
Query: 409 QDHDDVLWLATNASAGPYMAVVSTSKF 489
+ +D+ W+ T+ PYM ++ + F
Sbjct: 77 EKEEDLQWVLTDGPNPPYMVLLESKHF 103
>AJ430032-1|CAD22550.1| 1156|Homo sapiens mucin 4 protein.
Length = 1156
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 591 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 648
>AJ400858-1|CAC14143.1| 2167|Homo sapiens MUC4 protein splice variant
sv21 protein.
Length = 2167
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 1604 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 1661
>AJ400857-1|CAC14142.1| 1827|Homo sapiens MUC4 protein splice variant
sv20 protein.
Length = 1827
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 1604 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 1661
>AJ277412-1|CAC10061.1| 2117|Homo sapiens mucin 4, variant V3 protein.
Length = 2117
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 1552 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 1609
>AJ276359-1|CAB81773.1| 2169|Homo sapiens mucin 4 protein.
Length = 2169
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 1604 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 1661
>AJ242550-1|CAB85606.1| 1125|Homo sapiens MUC4/X apomucin protein.
Length = 1125
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 560 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 617
>AJ242549-1|CAB85605.1| 1176|Homo sapiens MUC4/Y apomucin protein.
Length = 1176
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 611 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 668
>AJ242548-1|CAB85604.1| 930|Homo sapiens sv8-MUC4 apomucin protein.
Length = 930
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 365 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 422
>AJ242547-1|CAB85603.1| 814|Homo sapiens sv7-MUC4 apomucin protein.
Length = 814
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 591 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 648
>AJ010901-1|CAB38059.1| 1156|Homo sapiens MUC4 protein.
Length = 1156
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 591 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 648
>AF522055-1|AAM66747.1| 2169|Homo sapiens MUC4 protein.
Length = 2169
Score = 31.9 bits (69), Expect = 2.6
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Frame = +1
Query: 583 DTRCPNEFSSADGNQCSSSKEGGVVWNEKGTGLL-KREIPFPIFFIPESRYEEIEKNQS 756
D R PN + G+ G+ W GTGLL KR P F P Y +++KN S
Sbjct: 1604 DFRMPNGSTIPPGSPEEMLFHFGMTWQINGTGLLGKRNDQLPSNFTPVF-YSQLQKNSS 1661
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,509,133
Number of Sequences: 237096
Number of extensions: 2255358
Number of successful extensions: 4201
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 4076
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4185
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9311505506
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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