Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt1a19
(705 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 223 5e-58
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 223 5e-58
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 223 5e-58
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 223 5e-58
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 210 4e-54
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 210 4e-54
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 210 4e-54
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 210 4e-54
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 210 4e-54
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 209 8e-54
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 201 2e-51
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 185 2e-46
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 185 2e-46
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 185 2e-46
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 180 4e-45
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 180 4e-45
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 180 4e-45
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 180 4e-45
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 163 5e-40
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 103 5e-22
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 103 5e-22
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 103 8e-22
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 75 3e-13
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 223 bits (545), Expect = 5e-58
Identities = 96/209 (45%), Positives = 131/209 (62%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 437 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 616
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 617 PIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ +P APY V+ AHA+ + YDE
Sbjct: 1082 GVKDPGWAPYRIAHTVIKAHARVYHTYDE 1110
Score = 214 bits (522), Expect = 3e-55
Identities = 100/209 (47%), Positives = 132/209 (63%), Gaps = 1/209 (0%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 259
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 260 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 439
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 440 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 619
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 620 IF-EPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ P APY+ +++ AHA+AW +Y++
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 189 bits (460), Expect = 1e-47
Identities = 95/212 (44%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 244
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 245 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 424
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 425 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 604
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 605 GMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I +P VA + VL AHA+ W Y+
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAHARTWHHYN 586
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +2
Query: 293 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 472
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 473 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 223 bits (545), Expect = 5e-58
Identities = 96/209 (45%), Positives = 131/209 (62%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 437 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 616
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 617 PIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ +P APY V+ AHA+ + YDE
Sbjct: 1082 GVKDPGWAPYRIAHAVIKAHARVYHTYDE 1110
Score = 214 bits (522), Expect = 3e-55
Identities = 100/209 (47%), Positives = 132/209 (63%), Gaps = 1/209 (0%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 259
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 260 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 439
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 440 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 619
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 620 IF-EPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ P APY+ +++ AHA+AW +Y++
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 189 bits (460), Expect = 1e-47
Identities = 95/212 (44%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 244
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 245 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 424
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 425 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 604
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 605 GMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I +P VA + VL AHA+ W Y+
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAHARTWHHYN 586
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +2
Query: 293 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 472
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 473 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 223 bits (545), Expect = 5e-58
Identities = 96/209 (45%), Positives = 131/209 (62%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 334 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 393
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 394 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 453
Query: 437 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 616
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 454 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 513
Query: 617 PIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ +P APY V+ AHA+ + YDE
Sbjct: 514 GVKDPGWAPYRIAHTVIKAHARVYHTYDE 542
Score = 191 bits (466), Expect = 2e-48
Identities = 90/179 (50%), Positives = 113/179 (63%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 259
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 867
Query: 260 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 439
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 440 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 616
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 223 bits (545), Expect = 5e-58
Identities = 96/209 (45%), Positives = 131/209 (62%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 437 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 616
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 617 PIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ +P APY V+ AHA+ + YDE
Sbjct: 1082 GVKDPGWAPYRIAHAVIKAHARVYHTYDE 1110
Score = 214 bits (522), Expect = 3e-55
Identities = 100/209 (47%), Positives = 132/209 (63%), Gaps = 1/209 (0%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 259
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 260 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 439
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 440 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 619
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 620 IF-EPHVAPYVCTKHVLLAHAKAWRIYDE 703
+ P APY+ +++ AHA+AW +Y++
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 189 bits (460), Expect = 1e-47
Identities = 95/212 (44%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 244
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 245 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 424
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 425 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 604
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 605 GMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I +P VA + VL AHA+ W Y+
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAHARTWHHYN 586
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +2
Query: 293 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 472
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 473 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 210 bits (513), Expect = 4e-54
Identities = 92/209 (44%), Positives = 129/209 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 434 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I Y +++ AHA++W YD
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 210 bits (513), Expect = 4e-54
Identities = 92/209 (44%), Positives = 129/209 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 434 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I Y +++ AHA++W YD
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 210 bits (513), Expect = 4e-54
Identities = 92/209 (44%), Positives = 129/209 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 434 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I Y +++ AHA++W YD
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 210 bits (513), Expect = 4e-54
Identities = 92/209 (44%), Positives = 129/209 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 434 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I Y +++ AHA++W YD
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 210 bits (513), Expect = 4e-54
Identities = 92/209 (44%), Positives = 129/209 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 434 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I Y +++ AHA++W YD
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 209 bits (510), Expect = 8e-54
Identities = 92/209 (44%), Positives = 128/209 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 434 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
+DLPQ+L+D GGW + I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P I Y +++ AHA++W YD
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 201 bits (491), Expect = 2e-51
Identities = 90/210 (42%), Positives = 129/210 (61%), Gaps = 2/210 (0%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TFP GF +G S++YQ EGAW+ KG SIWD H+ ++ DV CD Y+ +
Sbjct: 36 TFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQE 95
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGF-SNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 433
DI + EL ++ YRFSLSWPRL+PTG + ++++ G ++Y++LID LL I P+VT+ H
Sbjct: 96 DIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHH 155
Query: 434 WDLPQSLQ-DLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGM 610
WDLPQ LQ GGW N + ++F DYA + F F DRVK W++ ++P ++ + Y TG
Sbjct: 156 WDLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHH 215
Query: 611 APPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
AP + Y H++ AHAK W Y+
Sbjct: 216 APGLKLRGTGLYKAAHHIIKAHAKTWHSYN 245
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 185 bits (450), Expect = 2e-46
Identities = 87/209 (41%), Positives = 124/209 (59%), Gaps = 1/209 (0%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 437 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P A Y +++ AH+K W Y+
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 101 bits (241), Expect = 3e-21
Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 12/219 (5%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 238
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 239 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 418
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 419 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 583
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 584 DYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
D +YN G Y ++L+AHA AWR+YD
Sbjct: 699 D-IYNRSGN---------DTYGAAHNLLVAHALAWRLYD 727
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 185 bits (450), Expect = 2e-46
Identities = 87/209 (41%), Positives = 124/209 (59%), Gaps = 1/209 (0%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 437 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P A Y +++ AH+K W Y+
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 101 bits (241), Expect = 3e-21
Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 12/219 (5%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 238
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 239 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 418
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 419 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 583
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 584 DYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
D +YN G Y ++L+AHA AWR+YD
Sbjct: 699 D-IYNRSGN---------DTYGAAHNLLVAHALAWRLYD 727
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 185 bits (450), Expect = 2e-46
Identities = 87/209 (41%), Positives = 124/209 (59%), Gaps = 1/209 (0%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 256
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 257 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 436
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 437 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 613
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 614 PPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P A Y +++ AH+K W Y+
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 101 bits (241), Expect = 3e-21
Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 12/219 (5%)
Frame = +2
Query: 80 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 238
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 239 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 418
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 419 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 583
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 584 DYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
D +YN G Y ++L+AHA AWR+YD
Sbjct: 699 D-IYNRSGN---------DTYGAAHNLLVAHALAWRLYD 727
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 180 bits (438), Expect = 4e-45
Identities = 91/224 (40%), Positives = 124/224 (55%), Gaps = 16/224 (7%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 217
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 218 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 391
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 392 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 569 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P + + Y TG +AP I Y+ ++LLAHAK W +Y+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 74.5 bits (175), Expect = 3e-13
Identities = 61/221 (27%), Positives = 96/221 (43%), Gaps = 12/221 (5%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 235
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 236 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 415
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 416 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSI 580
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP--- 690
Query: 581 CDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
Y N Y ++L AHA AW +Y+E
Sbjct: 691 --YTRN-------------MTYSAGHNLLKAHALAWHVYNE 716
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 180 bits (438), Expect = 4e-45
Identities = 91/224 (40%), Positives = 124/224 (55%), Gaps = 16/224 (7%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 217
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 218 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 391
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 392 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 569 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P + + Y TG +AP I Y+ ++LLAHAK W +Y+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 180 bits (438), Expect = 4e-45
Identities = 91/224 (40%), Positives = 124/224 (55%), Gaps = 16/224 (7%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 217
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 218 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 391
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 392 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 569 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P + + Y TG +AP I Y+ ++LLAHAK W +Y+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 74.5 bits (175), Expect = 3e-13
Identities = 61/221 (27%), Positives = 96/221 (43%), Gaps = 12/221 (5%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 235
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 236 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 415
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 416 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSI 580
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP--- 690
Query: 581 CDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
Y N Y ++L AHA AW +Y+E
Sbjct: 691 --YTRN-------------MTYSAGHNLLKAHALAWHVYNE 716
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 180 bits (438), Expect = 4e-45
Identities = 91/224 (40%), Positives = 124/224 (55%), Gaps = 16/224 (7%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 217
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 218 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 391
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 392 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 569 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYD 700
P + + Y TG +AP I Y+ ++LLAHAK W +Y+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 74.5 bits (175), Expect = 3e-13
Identities = 61/221 (27%), Positives = 96/221 (43%), Gaps = 12/221 (5%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 235
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 236 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 415
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 416 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSI 580
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP--- 690
Query: 581 CDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
Y N Y ++L AHA AW +Y+E
Sbjct: 691 --YTRN-------------MTYSAGHNLLKAHALAWHVYNE 716
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 163 bits (396), Expect = 5e-40
Identities = 85/214 (39%), Positives = 116/214 (54%), Gaps = 16/214 (7%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 217
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 218 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 391
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 392 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 568
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 569 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLL 670
P + + Y TG +AP I Y+ ++LL
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 5e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 355
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 5e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 355
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (246), Expect = 8e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +2
Query: 74 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 253
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 254 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 355
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 74.5 bits (175), Expect = 3e-13
Identities = 61/221 (27%), Positives = 96/221 (43%), Gaps = 12/221 (5%)
Frame = +2
Query: 77 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 235
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 245 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 300
Query: 236 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 415
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 301 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 360
Query: 416 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSI 580
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 361 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP--- 417
Query: 581 CDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAHAKAWRIYDE 703
Y N Y ++L AHA AW +Y+E
Sbjct: 418 --YTRN-------------MTYSAGHNLLKAHALAWHVYNE 443
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,087,427
Number of Sequences: 237096
Number of extensions: 2628827
Number of successful extensions: 12822
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 12590
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12785
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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