Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt19j16
(627 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT009807-1|AAP88809.1| 568|Homo sapiens numb homolog (Drosophil... 121 2e-27
AF015041-1|AAD01549.1| 609|Homo sapiens NUMB-R protein protein. 121 2e-27
BC068476-1|AAH68476.1| 592|Homo sapiens numb homolog (Drosophil... 120 6e-27
BC020788-1|AAH20788.1| 245|Homo sapiens NUMB protein protein. 120 6e-27
AF171941-1|AAD54282.1| 592|Homo sapiens NUMB isoform 4 protein. 120 6e-27
AF171940-1|AAD54281.1| 640|Homo sapiens NUMB isoform 3 protein. 120 6e-27
AF108092-1|AAD27959.1| 603|Homo sapiens NUMB protein protein. 110 5e-24
AF171939-1|AAD54280.1| 603|Homo sapiens NUMB isoform 2 protein. 109 6e-24
AF171938-1|AAD54279.1| 651|Homo sapiens NUMB isoform 1 protein. 109 6e-24
AF015040-1|AAD01548.1| 603|Homo sapiens NUMB protein protein. 109 6e-24
AF109907-4|AAC97962.1| 525|Homo sapiens S171 protein. 46 1e-04
D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc prot... 30 5.8
D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc prot... 30 5.8
D80008-1|BAA11503.2| 226|Homo sapiens KIAA0186 protein. 30 5.8
BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 dom... 30 5.8
BC012542-1|AAH12542.1| 196|Homo sapiens GINS1 protein protein. 30 5.8
AL353812-5|CAI13764.1| 196|Homo sapiens RP4-691N24.2 protein. 30 5.8
AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 dom... 30 5.8
AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 dom... 30 5.8
AL031672-3|CAI43019.1| 196|Homo sapiens RP4-691N24.2 protein. 30 5.8
AB001451-1|BAA25798.1| 540|Homo sapiens Sck protein. 30 5.8
>BT009807-1|AAP88809.1| 568|Homo sapiens numb homolog
(Drosophila)-like protein.
Length = 568
Score = 121 bits (292), Expect = 2e-27
Identities = 55/84 (65%), Positives = 70/84 (83%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAV 555
PE++RPHQW ADE AVR GTC+FPV+YLG VEV ESRGM VCE+A+K L+ R+ +++V
Sbjct: 17 PEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSV 76
Query: 556 LHVSGDGLRVVEEETKGLIVDQTI 627
L VS DGLRVV+++TK L+VDQTI
Sbjct: 77 LWVSADGLRVVDDKTKDLLVDQTI 100
>AF015041-1|AAD01549.1| 609|Homo sapiens NUMB-R protein protein.
Length = 609
Score = 121 bits (292), Expect = 2e-27
Identities = 55/84 (65%), Positives = 70/84 (83%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAV 555
PE++RPHQW ADE AVR GTC+FPV+YLG VEV ESRGM VCE+A+K L+ R+ +++V
Sbjct: 58 PEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSV 117
Query: 556 LHVSGDGLRVVEEETKGLIVDQTI 627
L VS DGLRVV+++TK L+VDQTI
Sbjct: 118 LWVSADGLRVVDDKTKDLLVDQTI 141
>BC068476-1|AAH68476.1| 592|Homo sapiens numb homolog (Drosophila)
protein.
Length = 592
Score = 120 bits (288), Expect = 6e-27
Identities = 54/84 (64%), Positives = 68/84 (80%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAV 555
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ + ++ ++AV
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKAV 76
Query: 556 LHVSGDGLRVVEEETKGLIVDQTI 627
L VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 LWVSADGLRVVDEKTKDLIVDQTI 100
>BC020788-1|AAH20788.1| 245|Homo sapiens NUMB protein protein.
Length = 245
Score = 120 bits (288), Expect = 6e-27
Identities = 54/84 (64%), Positives = 68/84 (80%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAV 555
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ + ++ ++AV
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKAV 76
Query: 556 LHVSGDGLRVVEEETKGLIVDQTI 627
L VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 LWVSADGLRVVDEKTKDLIVDQTI 100
>AF171941-1|AAD54282.1| 592|Homo sapiens NUMB isoform 4 protein.
Length = 592
Score = 120 bits (288), Expect = 6e-27
Identities = 54/84 (64%), Positives = 68/84 (80%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAV 555
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ + ++ ++AV
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKAV 76
Query: 556 LHVSGDGLRVVEEETKGLIVDQTI 627
L VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 LWVSADGLRVVDEKTKDLIVDQTI 100
>AF171940-1|AAD54281.1| 640|Homo sapiens NUMB isoform 3 protein.
Length = 640
Score = 120 bits (288), Expect = 6e-27
Identities = 54/84 (64%), Positives = 68/84 (80%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAV 555
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ + ++ ++AV
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKAV 76
Query: 556 LHVSGDGLRVVEEETKGLIVDQTI 627
L VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 LWVSADGLRVVDEKTKDLIVDQTI 100
>AF108092-1|AAD27959.1| 603|Homo sapiens NUMB protein protein.
Length = 603
Score = 110 bits (264), Expect = 5e-24
Identities = 55/95 (57%), Positives = 69/95 (72%), Gaps = 11/95 (11%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSR------- 534
PE++RPHQW DE +VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ R
Sbjct: 17 PEASRPHQWQTDEESVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAQRKFFKGFF 76
Query: 535 ----RRPIRAVLHVSGDGLRVVEEETKGLIVDQTI 627
++ ++AVL VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 GKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTI 111
>AF171939-1|AAD54280.1| 603|Homo sapiens NUMB isoform 2 protein.
Length = 603
Score = 109 bits (263), Expect = 6e-24
Identities = 55/95 (57%), Positives = 68/95 (71%), Gaps = 11/95 (11%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSR------- 534
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ R
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFF 76
Query: 535 ----RRPIRAVLHVSGDGLRVVEEETKGLIVDQTI 627
++ ++AVL VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 GKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTI 111
>AF171938-1|AAD54279.1| 651|Homo sapiens NUMB isoform 1 protein.
Length = 651
Score = 109 bits (263), Expect = 6e-24
Identities = 55/95 (57%), Positives = 68/95 (71%), Gaps = 11/95 (11%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSR------- 534
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ R
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFF 76
Query: 535 ----RRPIRAVLHVSGDGLRVVEEETKGLIVDQTI 627
++ ++AVL VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 GKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTI 111
>AF015040-1|AAD01548.1| 603|Homo sapiens NUMB protein protein.
Length = 603
Score = 109 bits (263), Expect = 6e-24
Identities = 55/95 (57%), Positives = 68/95 (71%), Gaps = 11/95 (11%)
Frame = +1
Query: 376 PESARPHQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSR------- 534
PE++RPHQW DE VR G C+FPVKYLG VEV ESRGM +CE+A+K L+ R
Sbjct: 17 PEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFF 76
Query: 535 ----RRPIRAVLHVSGDGLRVVEEETKGLIVDQTI 627
++ ++AVL VS DGLRVV+E+TK LIVDQTI
Sbjct: 77 GKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTI 111
>AF109907-4|AAC97962.1| 525|Homo sapiens S171 protein.
Length = 525
Score = 46.0 bits (104), Expect = 1e-04
Identities = 21/31 (67%), Positives = 27/31 (87%)
Frame = +1
Query: 535 RRPIRAVLHVSGDGLRVVEEETKGLIVDQTI 627
++ ++AVL VS DGLRVV+E+TK LIVDQTI
Sbjct: 3 KKAVKAVLWVSADGLRVVDEKTKDLIVDQTI 33
>D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc
protein.
Length = 474
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +1
Query: 403 HADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAVLHVSG 570
HA + + G T+ VKYLGC+EV S ++ R + R AV G
Sbjct: 23 HASDQVLGPGV-TYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGAKG 77
>D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc
protein.
Length = 594
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +1
Query: 403 HADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAVLHVSG 570
HA + + G T+ VKYLGC+EV S ++ R + R AV G
Sbjct: 143 HASDQVLGPGV-TYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGAKG 197
>D80008-1|BAA11503.2| 226|Homo sapiens KIAA0186 protein.
Length = 226
Score = 30.3 bits (65), Expect = 5.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 499 CEEALKVLRNSRRRPIRAVLHVSGDGLRVVEEETKGL 609
CE+A++++R R P + + DGLR V EE K L
Sbjct: 33 CEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKAL 69
>BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +1
Query: 403 HADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAVLHVSG 570
HA + + G T+ VKYLGC+EV S ++ R + R AV G
Sbjct: 143 HASDQVLGPGV-TYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGAKG 197
>BC012542-1|AAH12542.1| 196|Homo sapiens GINS1 protein protein.
Length = 196
Score = 30.3 bits (65), Expect = 5.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 499 CEEALKVLRNSRRRPIRAVLHVSGDGLRVVEEETKGL 609
CE+A++++R R P + + DGLR V EE K L
Sbjct: 3 CEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKAL 39
>AL353812-5|CAI13764.1| 196|Homo sapiens RP4-691N24.2 protein.
Length = 196
Score = 30.3 bits (65), Expect = 5.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 499 CEEALKVLRNSRRRPIRAVLHVSGDGLRVVEEETKGL 609
CE+A++++R R P + + DGLR V EE K L
Sbjct: 3 CEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKAL 39
>AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +1
Query: 403 HADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAVLHVSG 570
HA + + G T+ VKYLGC+EV S ++ R + R AV G
Sbjct: 143 HASDQVLGPGV-TYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGAKG 197
>AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/56 (32%), Positives = 25/56 (44%)
Frame = +1
Query: 403 HADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAVLHVSG 570
HA + + G T+ VKYLGC+EV S ++ R + R AV G
Sbjct: 143 HASDQVLGPGV-TYVVKYLGCIEVLRSMRSLDFSTRTQITREAISRVCEAVPGAKG 197
>AL031672-3|CAI43019.1| 196|Homo sapiens RP4-691N24.2 protein.
Length = 196
Score = 30.3 bits (65), Expect = 5.8
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 499 CEEALKVLRNSRRRPIRAVLHVSGDGLRVVEEETKGL 609
CE+A++++R R P + + DGLR V EE K L
Sbjct: 3 CEKAMELIRELHRAPEGQLPAFNEDGLRQVLEEMKAL 39
>AB001451-1|BAA25798.1| 540|Homo sapiens Sck protein.
Length = 540
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/59 (30%), Positives = 26/59 (44%)
Frame = +1
Query: 394 HQWHADEAAVRAGTCTFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRAVLHVSG 570
H W +A V ++ V+Y+GC+EV S +V R + R AV V G
Sbjct: 95 HGWLHPDARVLGPGVSYVVRYMGCIEVLRSMRSLDFNTRTQVTREAINRLHEAVPGVRG 153
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,120,530
Number of Sequences: 237096
Number of extensions: 1253145
Number of successful extensions: 3539
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3436
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3535
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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