Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt19d24
(721 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 123 6e-28
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 123 6e-28
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 123 6e-28
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 123 6e-28
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 105 2e-22
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 96 1e-19
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 84 6e-16
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 84 6e-16
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 71 3e-12
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 71 3e-12
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 71 3e-12
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 71 3e-12
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 66 1e-10
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 66 1e-10
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 66 1e-10
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 64 4e-10
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 64 4e-10
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 64 4e-10
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 64 4e-10
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 64 4e-10
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 64 4e-10
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 64 4e-10
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 64 4e-10
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 62 1e-09
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 62 1e-09
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 56 2e-07
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 56 2e-07
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 56 2e-07
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 56 2e-07
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 56 2e-07
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 55 2e-07
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 55 3e-07
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 55 3e-07
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 54 4e-07
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 54 4e-07
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 54 4e-07
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 54 4e-07
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 54 5e-07
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 54 5e-07
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 54 5e-07
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 54 5e-07
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 54 5e-07
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 54 5e-07
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 53 9e-07
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 53 9e-07
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 53 9e-07
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 53 9e-07
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 53 9e-07
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 53 9e-07
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 53 1e-06
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 53 1e-06
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 53 1e-06
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 53 1e-06
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 53 1e-06
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 53 1e-06
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 53 1e-06
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 52 2e-06
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 51 5e-06
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 51 5e-06
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 51 5e-06
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 51 5e-06
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 51 5e-06
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 51 5e-06
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 51 5e-06
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 51 5e-06
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 51 5e-06
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 51 5e-06
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 51 5e-06
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 51 5e-06
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 51 5e-06
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 49 2e-05
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 49 2e-05
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 49 2e-05
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 49 2e-05
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 49 2e-05
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 49 2e-05
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 49 2e-05
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 49 2e-05
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 49 2e-05
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 49 2e-05
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 48 3e-05
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 48 4e-05
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 48 4e-05
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 48 4e-05
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 47 6e-05
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 47 6e-05
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 47 6e-05
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 47 6e-05
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 47 6e-05
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 47 6e-05
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 47 6e-05
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 47 6e-05
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 47 6e-05
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 47 6e-05
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 46 2e-04
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 45 3e-04
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 45 3e-04
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 45 3e-04
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 45 3e-04
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 45 3e-04
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 45 3e-04
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 45 3e-04
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 45 3e-04
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 45 3e-04
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 45 3e-04
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 45 3e-04
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 45 3e-04
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 44 4e-04
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 44 4e-04
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 44 4e-04
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 44 4e-04
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 44 4e-04
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 44 4e-04
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 44 4e-04
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 44 7e-04
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 44 7e-04
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 44 7e-04
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 44 7e-04
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 44 7e-04
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 44 7e-04
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 44 7e-04
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 44 7e-04
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 44 7e-04
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 44 7e-04
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 44 7e-04
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 44 7e-04
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 44 7e-04
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 44 7e-04
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 44 7e-04
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 44 7e-04
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 44 7e-04
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 44 7e-04
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 44 7e-04
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 44 7e-04
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 44 7e-04
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 44 7e-04
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 44 7e-04
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 44 7e-04
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 44 7e-04
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 44 7e-04
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 43 0.001
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 43 0.001
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 43 0.001
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 43 0.001
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 42 0.002
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 42 0.002
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 42 0.002
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 42 0.002
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 42 0.002
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 42 0.002
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 41 0.004
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 41 0.004
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 41 0.004
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 41 0.004
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 41 0.004
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 41 0.005
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 41 0.005
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 41 0.005
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 40 0.009
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 39 0.016
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 39 0.016
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 39 0.016
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 39 0.016
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 39 0.016
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 39 0.016
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 39 0.021
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 39 0.021
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 38 0.027
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.027
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 38 0.027
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 38 0.027
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.027
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.027
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 38 0.027
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.027
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.027
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.027
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.027
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.027
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.027
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 38 0.027
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 38 0.027
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 38 0.027
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 38 0.027
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 38 0.048
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 37 0.063
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 36 0.11
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 36 0.11
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 36 0.19
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 36 0.19
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 36 0.19
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 35 0.34
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 35 0.34
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 35 0.34
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 33 0.78
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 33 0.78
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 32 1.8
M77144-1|AAA36014.1| 372|Homo sapiens 3-beta-hydroxysteroid deh... 32 1.8
M67466-1|AAA36016.1| 372|Homo sapiens 3-beta-hydroxysteroid deh... 32 1.8
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 32 1.8
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 32 1.8
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 32 1.8
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 32 1.8
BC131488-1|AAI31489.1| 372|Homo sapiens HSD3B2 protein protein. 32 1.8
BC038419-1|AAH38419.1| 372|Homo sapiens hydroxy-delta-5-steroid... 32 1.8
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 32 1.8
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 32 1.8
BC007230-1|AAH07230.1| 494|Homo sapiens COCH protein protein. 32 1.8
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 32 1.8
AY916789-1|AAW82432.1| 550|Homo sapiens coagulation factor C ho... 32 1.8
AY358900-1|AAQ89259.1| 550|Homo sapiens COCH protein. 32 1.8
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 32 1.8
AL359553-5|CAC19799.1| 372|Homo sapiens hydroxy-delta-5-steroid... 32 1.8
AL359553-4|CAI23079.1| 195|Homo sapiens hydroxy-delta-5-steroid... 32 1.8
AK222997-1|BAD96717.1| 372|Homo sapiens hydroxy-delta-5-steroid... 32 1.8
AK130273-1|BAC85316.1| 401|Homo sapiens protein ( Homo sapiens ... 32 1.8
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 32 1.8
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 32 1.8
AF006740-1|AAC39545.1| 550|Homo sapiens Coch-5B2 protein. 32 1.8
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 32 2.4
D50419-1|BAA23362.1| 711|Homo sapiens OTK18 protein. 31 4.1
BC052997-1|AAH52997.1| 711|Homo sapiens zinc finger protein 175... 31 4.1
AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid ... 31 4.1
AC018755-1|AAF87843.1| 711|Homo sapiens zinc finger protein 175... 31 4.1
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 31 5.5
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 30 9.6
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 30 9.6
AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein. 30 9.6
AL023881-2|CAO77955.1| 81|Homo sapiens 2,4-dienoyl CoA reducta... 30 9.6
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 30 9.6
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 30 9.6
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 123 bits (297), Expect = 6e-28
Identities = 67/203 (33%), Positives = 115/203 (56%), Gaps = 2/203 (0%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTLFIQCD 64
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 402
V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 403 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 582
K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182
Query: 583 FGATDTALLTD-EKLGTFDKYLE 648
G +TA+L EK +Y+E
Sbjct: 183 PGFVNTAILESIEKEENMGQYIE 205
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 123 bits (297), Expect = 6e-28
Identities = 67/203 (33%), Positives = 115/203 (56%), Gaps = 2/203 (0%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTLFIQCD 64
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 402
V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 403 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 582
K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182
Query: 583 FGATDTALLTD-EKLGTFDKYLE 648
G +TA+L EK +Y+E
Sbjct: 183 PGFVNTAILESIEKEENMGQYIE 205
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 123 bits (297), Expect = 6e-28
Identities = 67/203 (33%), Positives = 115/203 (56%), Gaps = 2/203 (0%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 402
V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 403 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 582
K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182
Query: 583 FGATDTALLTD-EKLGTFDKYLE 648
G +TA+L EK +Y+E
Sbjct: 183 PGFVNTAILESIEKEENMGQYIE 205
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 123 bits (297), Expect = 6e-28
Identities = 67/203 (33%), Positives = 115/203 (56%), Gaps = 2/203 (0%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 402
V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 403 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 582
K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182
Query: 583 FGATDTALLTD-EKLGTFDKYLE 648
G +TA+L EK +Y+E
Sbjct: 183 PGFVNTAILESIEKEENMGQYIE 205
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 105 bits (251), Expect = 2e-22
Identities = 55/160 (34%), Positives = 94/160 (58%), Gaps = 1/160 (0%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 402
V D++ VV G +D+++NNA + N ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNKKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 403 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
K +GG+GG +IN+SS+A L P+Y A+K ++ F+
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 96.3 bits (229), Expect = 1e-19
Identities = 50/139 (35%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYG-NKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 402
V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122
Query: 403 GKHSGGKGGTVINVSSVAA 459
K +GG+GG +IN+SS+AA
Sbjct: 123 SKQNGGEGGIIINMSSLAA 141
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 83.8 bits (198), Expect = 6e-16
Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 11/199 (5%)
Frame = +1
Query: 37 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSK-YGNKTK 207
W+D++ +TGA+ GIG +V R L+ +G+K ++ A G + L AE S Y
Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65
Query: 208 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 369
YR D+++EE L + +A+ + G+D+ INNA L++ S +K VNV AL
Sbjct: 66 PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 543
T +A + M K G +IN++S++ + V Y ATK AV + + +
Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184
Query: 544 HFSKTGVRVLTVCFGATDT 600
++T +R + G +T
Sbjct: 185 REAQTHIRATCISPGVVET 203
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 83.8 bits (198), Expect = 6e-16
Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 11/199 (5%)
Frame = +1
Query: 37 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSK-YGNKTK 207
W+D++ +TGA+ GIG +V R L+ +G+K ++ A G + L AE S Y
Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65
Query: 208 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 369
YR D+++EE L + +A+ + G+D+ INNA L++ S +K VNV AL
Sbjct: 66 PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 543
T +A + M K G +IN++S++ + V Y ATK AV + + +
Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184
Query: 544 HFSKTGVRVLTVCFGATDT 600
++T +R + G +T
Sbjct: 185 REAQTHIRATCISPGVVET 203
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 71.3 bits (167), Expect = 3e-12
Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 384
T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 385 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 561
A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176
Query: 562 VRVLTVCFGATDTAL 606
VRV + G T L
Sbjct: 177 VRVNCISPGNIWTPL 191
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 71.3 bits (167), Expect = 3e-12
Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 384
T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 385 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 561
A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176
Query: 562 VRVLTVCFGATDTAL 606
VRV + G T L
Sbjct: 177 VRVNCISPGNIWTPL 191
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 71.3 bits (167), Expect = 3e-12
Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 384
T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 385 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 561
A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176
Query: 562 VRVLTVCFGATDTAL 606
VRV + G T L
Sbjct: 177 VRVNCISPGNIWTPL 191
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 71.3 bits (167), Expect = 3e-12
Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV
Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 384
T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T
Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123
Query: 385 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 561
A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176
Query: 562 VRVLTVCFGATDTAL 606
VRV + G T L
Sbjct: 177 VRVNCISPGNIWTPL 191
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 66.1 bits (154), Expect = 1e-10
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 10/212 (4%)
Frame = +1
Query: 34 EWK--DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAEL-NSKYGNKT 204
EW+ D VV++TGA++GIGE + L GV + E + + L N K
Sbjct: 45 EWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKD 104
Query: 205 KFYRS-DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVT 363
D+TD AV+QE G ID+++NN + M+ S+ +Y+K IE+N
Sbjct: 105 ILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYL 164
Query: 364 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 543
++ T + M + GK ++ V+S+ + + Y A+K A+ F N + R E
Sbjct: 165 GTVSLTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFNGL-RTE 220
Query: 544 HFSKTGVRVLTVCFGATDTALLTDEKLGTFDK 639
+ G+ V +C G + ++ + G K
Sbjct: 221 LATYPGIIVSNICPGPVQSNIVENSLAGEVTK 252
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 66.1 bits (154), Expect = 1e-10
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 10/212 (4%)
Frame = +1
Query: 34 EWK--DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAEL-NSKYGNKT 204
EW+ D VV++TGA++GIGE + L GV + E + + L N K
Sbjct: 45 EWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKD 104
Query: 205 KFYRS-DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVT 363
D+TD AV+QE G ID+++NN + M+ S+ +Y+K IE+N
Sbjct: 105 ILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYL 164
Query: 364 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 543
++ T + M + GK ++ V+S+ + + Y A+K A+ F N + R E
Sbjct: 165 GTVSLTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFNGL-RTE 220
Query: 544 HFSKTGVRVLTVCFGATDTALLTDEKLGTFDK 639
+ G+ V +C G + ++ + G K
Sbjct: 221 LATYPGIIVSNICPGPVQSNIVENSLAGEVTK 252
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 66.1 bits (154), Expect = 1e-10
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 10/212 (4%)
Frame = +1
Query: 34 EWK--DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAEL-NSKYGNKT 204
EW+ D VV++TGA++GIGE + L GV + E + + L N K
Sbjct: 45 EWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKD 104
Query: 205 KFYRS-DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVT 363
D+TD AV+QE G ID+++NN + M+ S+ +Y+K IE+N
Sbjct: 105 ILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYL 164
Query: 364 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 543
++ T + M + GK ++ V+S+ + + Y A+K A+ F N + R E
Sbjct: 165 GTVSLTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFNGL-RTE 220
Query: 544 HFSKTGVRVLTVCFGATDTALLTDEKLGTFDK 639
+ G+ V +C G + ++ + G K
Sbjct: 221 LATYPGIIVSNICPGPVQSNIVENSLAGEVTK 252
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 RPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
R + G+RV+T+ G T LLT EK+ F
Sbjct: 184 R--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 216
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/205 (26%), Positives = 94/205 (45%), Gaps = 8/205 (3%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAEL-NSKYGNKTKFYRS-D 222
VV++TGA++GIGE + L GV + E + + L N K D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 384
+TD AV+QE G ID+++NN + M+ S+ +Y+K IE+N ++ T
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 564
+ M + GK ++ V+S+ + + Y A+K A+ F N + R E + G+
Sbjct: 122 CVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFNGL-RTELATYPGI 177
Query: 565 RVLTVCFGATDTALLTDEKLGTFDK 639
V +C G + ++ + G K
Sbjct: 178 IVSNICPGPVQSNIVENSLAGEVTK 202
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/205 (26%), Positives = 94/205 (45%), Gaps = 8/205 (3%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAEL-NSKYGNKTKFYRS-D 222
VV++TGA++GIGE + L GV + E + + L N K D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 384
+TD AV+QE G ID+++NN + M+ S+ +Y+K IE+N ++ T
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 564
+ M + GK ++ V+S+ + + Y A+K A+ F N + R E + G+
Sbjct: 122 CVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFNGL-RTELATYPGI 177
Query: 565 RVLTVCFGATDTALLTDEKLGTFDK 639
V +C G + ++ + G K
Sbjct: 178 IVSNICPGPVQSNIVENSLAGEVTK 202
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ N V + +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 570
+ K K G +IN+SSVA+ + V +Y TK+AV+ + + F + G+R
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA--ADFIQQGIRC 172
Query: 571 LTVCFGATDTALLTD 615
VC G DT L +
Sbjct: 173 NCVCPGTVDTPSLQE 187
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/198 (23%), Positives = 88/198 (44%), Gaps = 4/198 (2%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
DKV + G + GIG +V +++ +G + +A++ E ++ +L G + D
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAAAGDL----GGDHLAFSCD 56
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV---TALITSTLKAI 393
V E + + G ++ ++N A + D + + K ++ T L+ S L
Sbjct: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 573
M +GG+++NV S+ L + +Y A+K ++ FS + + K V V+
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176
Query: 574 TVCFGATD-TALLTDEKL 624
F TD T L +E L
Sbjct: 177 APGFVHTDMTKDLKEEHL 194
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 55.6 bits (128), Expect = 2e-07
Identities = 47/198 (23%), Positives = 88/198 (44%), Gaps = 4/198 (2%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
DKV + G + GIG +V +++ +G + +A++ E ++ +L G + D
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAAAGDL----GGDHLAFSCD 56
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV---TALITSTLKAI 393
V E + + G ++ ++N A + D + + K ++ T L+ S L
Sbjct: 57 VAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 573
M +GG+++NV S+ L + +Y A+K ++ FS + + K V V+
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176
Query: 574 TVCFGATD-TALLTDEKL 624
F TD T L +E L
Sbjct: 177 APGFVHTDMTKDLKEEHL 194
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ N V + +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 570
+ K K G +IN+SSVA+ + V +Y TK+AV+ + + F + G+R
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA--ADFIQQGIRC 172
Query: 571 LTVCFGATDTALLTD 615
VC G DT L +
Sbjct: 173 NCVCPGTVDTPSLQE 187
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/168 (29%), Positives = 83/168 (49%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 14 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 70
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + + V+ GGID++++NAA LM+ + ++ K +++NV A
Sbjct: 71 HVGKAEDRERLVAM---AVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAP 127
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 128 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 172
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 55.2 bits (127), Expect = 2e-07
Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ ++ E +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQ----IDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 570
+ K K G +IN+SSVA+ + V +Y TK+AV+ + + F + G+R
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVA--ADFIQQGIRC 172
Query: 571 LTVCFGATDTALLTD 615
VC G DT L +
Sbjct: 173 NCVCPGTVDTPSLQE 187
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 54.8 bits (126), Expect = 3e-07
Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 11/174 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L + H+ + ++A +LQ E S G T
Sbjct: 30 NKVALVTASTDGIGFAIARRLAQDRA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 86
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + + V+ GGID++++NAA LM+ + ++ K +++NV A
Sbjct: 87 HVGKAEDRERLVAM---AVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAP 143
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
T + M K GG +V+ VSS+AA + S Y +K+A+L +N +
Sbjct: 144 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTL 194
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/195 (29%), Positives = 92/195 (47%), Gaps = 5/195 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ ++ E +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQ----IDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 570
+ K K G +IN+SSVA+ + V +Y TK+AV+ + + F + G+R
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLA--ADFIQQGIRC 172
Query: 571 LTVCFGATDTALLTD 615
VC G DT L +
Sbjct: 173 NCVCPGTVDTPSLQE 187
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 88
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + V+ GGID++++NAA +M+ + ++ K +++NV A
Sbjct: 89 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 145
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 146 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 190
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 88
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + V+ GGID++++NAA +M+ + ++ K +++NV A
Sbjct: 89 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 145
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 146 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 190
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 88
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + V+ GGID++++NAA +M+ + ++ K +++NV A
Sbjct: 89 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 145
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 146 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 190
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/168 (28%), Positives = 82/168 (48%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 14 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 70
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + V+ GGID++++NAA +M+ + ++ K +++NV A
Sbjct: 71 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 127
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 128 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 172
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 54.0 bits (124), Expect = 5e-07
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQA---ELNSKYGNKTKFYR 216
K V +TGA+ GIG + L G H+ + ++E Q + + EL + +
Sbjct: 35 KKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITS 378
D+T E F+ ++ GG+D++I N L +D I +K++EVN + +
Sbjct: 94 EDMTFAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVL 150
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T+ A+ ++ K S G+++ VSS+A ++ Y A+K A+ F + I + S+
Sbjct: 151 TVAALPML-KQS---NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRV 206
Query: 559 GVRVLTVCFGATDT 600
V + G DT
Sbjct: 207 NVSITLCVLGLIDT 220
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 54.0 bits (124), Expect = 5e-07
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQA---ELNSKYGNKTKFYR 216
K V +TGA+ GIG + L G H+ + ++E Q + + EL + +
Sbjct: 35 KKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITS 378
D+T E F+ ++ GG+D++I N L +D I +K++EVN + +
Sbjct: 94 EDMTFAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVL 150
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T+ A+ ++ K S G+++ VSS+A ++ Y A+K A+ F + I + S+
Sbjct: 151 TVAALPML-KQS---NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRV 206
Query: 559 GVRVLTVCFGATDT 600
V + G DT
Sbjct: 207 NVSITLCVLGLIDT 220
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 54.0 bits (124), Expect = 5e-07
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQA---ELNSKYGNKTKFYR 216
K V +TGA+ GIG + L G H+ + ++E Q + + EL + +
Sbjct: 35 KKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITS 378
D+T E F+ ++ GG+D++I N L +D I +K++EVN + +
Sbjct: 94 EDMTFAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVL 150
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T+ A+ ++ K S G+++ VSS+A ++ Y A+K A+ F + I + S+
Sbjct: 151 TVAALPML-KQS---NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRV 206
Query: 559 GVRVLTVCFGATDT 600
V + G DT
Sbjct: 207 NVSITLCVLGLIDT 220
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 54.0 bits (124), Expect = 5e-07
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQA---ELNSKYGNKTKFYR 216
K V +TGA+ GIG + L G H+ + ++E Q + + EL + +
Sbjct: 35 KKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITS 378
D+T E F+ ++ GG+D++I N L +D I +K++EVN + +
Sbjct: 94 EDMTFAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVL 150
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T+ A+ ++ K S G+++ VSS+A ++ Y A+K A+ F + I + S+
Sbjct: 151 TVAALPML-KQS---NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRV 206
Query: 559 GVRVLTVCFGATDT 600
V + G DT
Sbjct: 207 NVSITLCVLGLIDT 220
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 54.0 bits (124), Expect = 5e-07
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 9/194 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQA---ELNSKYGNKTKFYR 216
K V +TGA+ GIG + L G H+ + ++E Q + + EL + +
Sbjct: 35 KKVIVTGASKGIGREMAYHLAKMGA-HVVVTARSKETLQKVVSHCLELGAASAHYIAGTM 93
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITS 378
D+T E F+ ++ GG+D++I N L +D I +K++EVN + +
Sbjct: 94 EDMTFAEQFVAQAGKLM---GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVL 150
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T+ A+ ++ K S G+++ VSS+A ++ Y A+K A+ F + I + S+
Sbjct: 151 TVAALPML-KQS---NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRV 206
Query: 559 GVRVLTVCFGATDT 600
V + G DT
Sbjct: 207 NVSITLCVLGLIDT 220
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 54.0 bits (124), Expect = 5e-07
Identities = 47/168 (27%), Positives = 83/168 (49%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMV 90
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+++ D E + V+ GGID++++NAA +M+ + ++ K +++NV A
Sbjct: 91 GKAE--DRERLVA---TAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 145
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 146 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 190
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 53.2 bits (122), Expect = 9e-07
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 6/209 (2%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTL 384
+ DV D + ++ +++ G ++VINNAA ++ + + A + ++ T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTA 173
Query: 385 KAIEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
+GK KG ++++++ A T S + + K+ V S + + K
Sbjct: 174 FVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA--AEWGKY 231
Query: 559 GVRVLTVCFGATDT--ALLTDEKLGTFDK 639
G+R + G T A + GTF+K
Sbjct: 232 GMRFNVIQPGPIKTKGAFSRLDPTGTFEK 260
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 53.2 bits (122), Expect = 9e-07
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 6/209 (2%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTL 384
+ DV D + ++ +++ G ++VINNAA ++ + + A + ++ T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTA 173
Query: 385 KAIEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
+GK KG ++++++ A T S + + K+ V S + + K
Sbjct: 174 FVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA--AEWGKY 231
Query: 559 GVRVLTVCFGATDT--ALLTDEKLGTFDK 639
G+R + G T A + GTF+K
Sbjct: 232 GMRFNVIQPGPIKTKGAFSRLDPTGTFEK 260
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 53.2 bits (122), Expect = 9e-07
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 6/209 (2%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTL 384
+ DV D + ++ +++ G ++VINNAA ++ + + A + ++ T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTA 173
Query: 385 KAIEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
+GK KG ++++++ A T S + + K+ V S + + K
Sbjct: 174 FVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA--AEWGKY 231
Query: 559 GVRVLTVCFGATDT--ALLTDEKLGTFDK 639
G+R + G T A + GTF+K
Sbjct: 232 GMRFNVIQPGPIKTKGAFSRLDPTGTFEK 260
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 53.2 bits (122), Expect = 9e-07
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 6/209 (2%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTL 384
+ DV D + ++ +++ G ++VINNAA ++ + + A + ++ T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTA 173
Query: 385 KAIEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
+GK KG ++++++ A T S + + K+ V S + + K
Sbjct: 174 FVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA--AEWGKY 231
Query: 559 GVRVLTVCFGATDT--ALLTDEKLGTFDK 639
G+R + G T A + GTF+K
Sbjct: 232 GMRFNVIQPGPIKTKGAFSRLDPTGTFEK 260
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 53.2 bits (122), Expect = 9e-07
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 6/209 (2%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTL 384
+ DV D + ++ +++ G ++VINNAA ++ + + A + ++ T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTA 173
Query: 385 KAIEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
+GK KG ++++++ A T S + + K+ V S + + K
Sbjct: 174 FVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA--AEWGKY 231
Query: 559 GVRVLTVCFGATDT--ALLTDEKLGTFDK 639
G+R + G T A + GTF+K
Sbjct: 232 GMRFNVIQPGPIKTKGAFSRLDPTGTFEK 260
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 53.2 bits (122), Expect = 9e-07
Identities = 48/209 (22%), Positives = 96/209 (45%), Gaps = 6/209 (2%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTL 384
+ DV D + ++ +++ G ++VINNAA ++ + + A + ++ T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTA 173
Query: 385 KAIEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
+GK KG ++++++ A T S + + K+ V S + + K
Sbjct: 174 FVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA--AEWGKY 231
Query: 559 GVRVLTVCFGATDT--ALLTDEKLGTFDK 639
G+R + G T A + GTF+K
Sbjct: 232 GMRFNVIQPGPIKTKGAFSRLDPTGTFEK 260
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 15/181 (8%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 R 537
R
Sbjct: 184 R 184
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
++ VV ITGA +G+G+ ++ G K + + A + L EL + + K + ++
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAK-LVLCGRNGGALEELIRELTASHATKVQTHKP 109
Query: 220 -----DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 366
D+TD + ++Q G +D+++NNA +M+ ++ + K+ +E N
Sbjct: 110 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 169
Query: 367 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ T + M K + G ++ +SS+ Y A+K A F +C+
Sbjct: 170 PVALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCL 221
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 237
+TG+ GIG+S L G+K + ++ +++ + +E+ K+ +T+ D E+
Sbjct: 55 VTGSTDGIGKSYAEELAKHGMK-VVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASED 113
Query: 238 HFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTALITSTLK 387
+ I + + GI ++NN + + D + KK I +N+ ++ T
Sbjct: 114 IYDKIKTGLAGLEIGI--LVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQL 171
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 567
+ M + S G ++N+SS + + ++ IY ATK+ V FS C+ E + GV
Sbjct: 172 VLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDFFSQCL--HEEYRSKGVF 226
Query: 568 VLTV 579
V +V
Sbjct: 227 VQSV 230
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
++ VV ITGA +G+G+ ++ G K + + A + L EL + + K + ++
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAK-LVLCGRNGGALEELIRELTASHATKVQTHKP 109
Query: 220 -----DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 366
D+TD + ++Q G +D+++NNA +M+ ++ + K+ +E N
Sbjct: 110 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 169
Query: 367 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ T + M K + G ++ +SS+ Y A+K A F +C+
Sbjct: 170 PVALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCL 221
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 15/181 (8%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 534
MG++ GG+ G +IN +SVAA Y A+K ++ + I
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 535 R 537
R
Sbjct: 184 R 184
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
++ VV ITGA +G+G+ ++ G K + + A + L EL + + K + ++
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAK-LVLCGRNGGALEELIRELTASHATKVQTHKP 109
Query: 220 -----DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 366
D+TD + ++Q G +D+++NNA +M+ ++ + K+ +E N
Sbjct: 110 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 169
Query: 367 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ T + M K + G ++ +SS+ Y A+K A F +C+
Sbjct: 170 PVALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCL 221
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
++ VV ITGA +G+G+ ++ G K + + A + L EL + + K + ++
Sbjct: 36 RNAVVVITGATSGLGKECAKVFYAAGAK-LVLCGRNGGALEELIRELTASHATKVQTHKP 94
Query: 220 -----DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 366
D+TD + ++Q G +D+++NNA +M+ ++ + K+ +E N
Sbjct: 95 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 154
Query: 367 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ T + M K + G ++ +SS+ Y A+K A F +C+
Sbjct: 155 PVALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCL 206
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/184 (24%), Positives = 87/184 (47%), Gaps = 10/184 (5%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTDEE 237
+TG+ GIG+S L G+K + ++ +++ + +E+ K+ +T+ D E+
Sbjct: 55 VTGSTDGIGKSYAEELAKHGMK-VVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASED 113
Query: 238 HFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTALITSTLK 387
+ I + + GI ++NN + + D + KK I +N+ ++ T
Sbjct: 114 IYDKIKTGLAGLEIGI--LVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQL 171
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 567
+ M + S G ++N+SS + + ++ IY ATK+ V FS C+ E + GV
Sbjct: 172 VLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDFFSQCL--HEEYRSKGVF 226
Query: 568 VLTV 579
V +V
Sbjct: 227 VQSV 230
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/168 (28%), Positives = 81/168 (48%), Gaps = 11/168 (6%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 32 NKVALATASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 88
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTAL 369
+ D E + V+ GGID++++NAA +M+ + ++ K +++NV A
Sbjct: 89 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 145
Query: 370 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
T + M K GG +V+ VSS+AA + S Y +K+A+L
Sbjct: 146 ALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSPYNVSKTALL 190
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
++ VV ITGA +G+G+ ++ G K + + A + L EL + + K + ++
Sbjct: 56 RNAVVVITGATSGLGKECAKVFYAAGAK-LVLCGRNGGALEELIRELTASHATKVQTHKP 114
Query: 220 -----DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 366
D+TD + ++Q G +D+++NNA +M+ ++ + K+ +E N
Sbjct: 115 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 174
Query: 367 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ T + M K + G ++ +SS+ Y A+K A F +C+
Sbjct: 175 PVALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCL 226
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 52.0 bits (119), Expect = 2e-06
Identities = 40/180 (22%), Positives = 80/180 (44%), Gaps = 3/180 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
DKV + G + GIG +V +++ +G + +A++ E ++ +L G + D
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYR-LAVIARNLEGAKAAAGDL----GGDHLAFSCD 56
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV---TALITSTLKAI 393
V E + + G ++ ++N A + D + + K ++ T L+ S L
Sbjct: 57 VAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 573
M +GG+++NV S+ L + +Y A+K ++ FS + + K V V+
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 50.8 bits (116), Expect = 5e-06
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 9/203 (4%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
+K VFITG +G G + + L+D G++ +A EE Q LQ + + Y +T D
Sbjct: 25 EKYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRD--TSYRLQTTLL--D 79
Query: 223 VTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSI--GIYKKAIEVNVTALIT 375
VT E V + G G+ ++NNA + N+ + + K I VN+ LI
Sbjct: 80 VTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
TL + M K + G+ V+N+SS + + Y +K V FS+ I R ++
Sbjct: 140 VTLHMLP-MVKRARGR---VVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYY-- 192
Query: 556 TGVRVLTVCFGATDTALLTDEKL 624
GV+V + G TA+L E L
Sbjct: 193 FGVKVCIIEPGNYRTAILGKENL 215
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 50.8 bits (116), Expect = 5e-06
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 9/203 (4%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
+K VFITG +G G + + L+D G++ +A EE Q LQ + + Y +T D
Sbjct: 25 EKYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRD--TSYRLQTTLL--D 79
Query: 223 VTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSI--GIYKKAIEVNVTALIT 375
VT E V + G G+ ++NNA + N+ + + K I VN+ LI
Sbjct: 80 VTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
TL + M K + G+ V+N+SS + + Y +K V FS+ I R ++
Sbjct: 140 VTLHMLP-MVKRARGR---VVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYY-- 192
Query: 556 TGVRVLTVCFGATDTALLTDEKL 624
GV+V + G TA+L E L
Sbjct: 193 FGVKVCIIEPGNYRTAILGKENL 215
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 50.8 bits (116), Expect = 5e-06
Identities = 61/203 (30%), Positives = 95/203 (46%), Gaps = 9/203 (4%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
+K VFITG +G G + + L+D G++ +A EE Q LQ + + Y +T D
Sbjct: 25 EKYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRD--TSYRLQTTLL--D 79
Query: 223 VTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSI--GIYKKAIEVNVTALIT 375
VT E V + G G+ ++NNA + N+ + + K I VN+ LI
Sbjct: 80 VTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
TL + M K + G+ V+N+SS + + Y +K V FS+ I R ++
Sbjct: 140 VTLHMLP-MVKRARGR---VVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYY-- 192
Query: 556 TGVRVLTVCFGATDTALLTDEKL 624
GV+V + G TA+L E L
Sbjct: 193 FGVKVCIIEPGNYRTAILGKENL 215
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/184 (30%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY 192
G LK+ + DK +FITG +G G R +G H+ + E +L+AE +
Sbjct: 20 GKLKIE-DITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETS--- 74
Query: 193 GNKTKFYRSDVTDEEHFLGILNAVVQEQG--GIDVVINNAAL-----MNDSIGI--YKKA 345
+ + DVTD E+ V + G G+ +INNA + D + + Y++
Sbjct: 75 -ERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREP 133
Query: 346 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 525
IEVN+ LI+ TL + ++ K G VINVSSV + V Y +K AV F++
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQ----GRVINVSSVGG-RLAIVGGGYTPSKYAVEGFND 188
Query: 526 CIGR 537
+ R
Sbjct: 189 SLRR 192
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 48.8 bits (111), Expect = 2e-05
Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 15/155 (9%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
K V ITG A+G+G + L+ +G + +LD+ G++ QA+ K GN F +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEA-QAK---KLGNNCVFAPA 63
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIGIYKKAIEVNVT 363
DVT E+ L + G +DV +N A + ++ +++ ++VN+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 364 ALITSTLKAIEIMGKH---SGGKGGTVINVSSVAA 459
MG++ GG+ G +IN +SVAA
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSKYGNKTKFYRS- 219
KVV +TGA TGIG+ + L G + ++A D+ E G+ + E+ + GN+ R
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRKL 99
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D++D + + E+ + V+INNA +M
Sbjct: 100 DLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/93 (27%), Positives = 51/93 (54%)
Frame = +1
Query: 31 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKF 210
+ ++ KV FITG TG+G+ + +L G + + I + ++ +++S+ GNK
Sbjct: 55 NSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA 309
+ DV D + ++ +++ G ++VINNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 47.6 bits (108), Expect = 4e-05
Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSK 189
G + + + KVV ITGA TGIG+ R L G + +IA D+ + G+S +E+
Sbjct: 29 GVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLK--GESAASEIRVD 86
Query: 190 YGNKTKFYRS-DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
N R D++D + + E+ + ++INNA +M
Sbjct: 87 TKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVM 129
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 47.6 bits (108), Expect = 4e-05
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 17/166 (10%)
Frame = +1
Query: 187 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------------MNDSIG 330
K GN F +DVT E+ L + G +DV +N A + ++
Sbjct: 3 KLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE 62
Query: 331 IYKKAIEVNVTALITSTLKAIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATK 501
+++ ++VN+ MG++ GG+ G +IN +SVAA Y A+K
Sbjct: 63 DFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASK 122
Query: 502 SAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDTALLTD--EKLGTF 633
++ + I R + G+RV+T+ G T LLT EK+ F
Sbjct: 123 GGIVGMTLPIAR--DLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNF 166
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 47.6 bits (108), Expect = 4e-05
Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = +1
Query: 13 GTLKMSHEWKDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGQSLQAELNSK 189
G + + + KVV ITGA TGIG+ R L G + +IA D+ + G+S +E+
Sbjct: 29 GVCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLK--GESAASEIRVD 86
Query: 190 YGNKTKFYRS-DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
N R D++D + + E+ + ++INNA +M
Sbjct: 87 TKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVM 129
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NADPH)
3, EC 1.1.1.284. protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 47.2 bits (107), Expect = 6e-05
Identities = 38/145 (26%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
+V +TGA GIG ++ R L + + + GQ+ +L ++ G +F++ D+
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDI 64
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAAL---MNDSIGIYKKA---IEVNVTALITSTLK 387
D + + + + +E GG++V++NNAA+ +D + KA ++ N A +
Sbjct: 65 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 124
Query: 388 AIEIMGKHSGGKGGTVINVSSVAAL 462
+ IM H G V+N+SS+ L
Sbjct: 125 LLPIMKPH-----GRVVNISSLQCL 144
>AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 72
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/65 (40%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV +TGAA GIG + LL +G K +A++D EAG +A L+ ++ KT F + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 223 VTDEE 237
V D++
Sbjct: 65 VADQQ 69
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 44.8 bits (101), Expect = 3e-04
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG G+G ++ + L + G A + E G + EL + + D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFA--GVLNENGPGAE-ELRRTCSPRLSVLQMDI 139
Query: 226 TDEEHFLGILN--AVVQEQGGIDVVINNAALM---NDS----IGIYKKAIEVNVTALITS 378
T + A + + G+ VINNA ++ D + YK+ + VN +
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T + ++ K G ++NVSS+ + Y ++K+AV FS+ + R E SK
Sbjct: 200 TKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSS-VMRLE-LSKW 253
Query: 559 GVRVLTVCFGATDTALLTDEKLGTFDKY--LESSCLDQL 669
G++V ++ G T + GT DK+ LE LD L
Sbjct: 254 GIKVASIQPGGFLTNI-----AGTSDKWEKLEKDILDHL 287
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 44.8 bits (101), Expect = 3e-04
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG G+G ++ + L + G A + E G + EL + + D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFA--GVLNENGPGAE-ELRRTCSPRLSVLQMDI 139
Query: 226 TDEEHFLGILN--AVVQEQGGIDVVINNAALM---NDS----IGIYKKAIEVNVTALITS 378
T + A + + G+ VINNA ++ D + YK+ + VN +
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T + ++ K G ++NVSS+ + Y ++K+AV FS+ + R E SK
Sbjct: 200 TKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSS-VMRLE-LSKW 253
Query: 559 GVRVLTVCFGATDTALLTDEKLGTFDKY--LESSCLDQL 669
G++V ++ G T + GT DK+ LE LD L
Sbjct: 254 GIKVASIQPGGFLTNI-----AGTSDKWEKLEKDILDHL 287
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 8/187 (4%)
Frame = +1
Query: 46 KVVFITGAATGIG-ESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V ITGA GIG ++ + + + + DI + + AE K G Y D
Sbjct: 37 EIVLITGAGHGIGRQTTYEFAKRQSI--LVLWDINKRGVEETAAECR-KLGVTAHAYVVD 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 384
++ E LN V +E G + +V+NNA L++ K EVN+ T
Sbjct: 94 CSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITK 153
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTG 561
+ M + + G ++ V+SV + Y ++K A + F + + KTG
Sbjct: 154 ALLPSMMERNHGH---IVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 562 VRVLTVC 582
++ +C
Sbjct: 211 IKTSCLC 217
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 8/187 (4%)
Frame = +1
Query: 46 KVVFITGAATGIG-ESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V ITGA GIG ++ + + + + DI + + AE K G Y D
Sbjct: 37 EIVLITGAGHGIGRQTTYEFAKRQSI--LVLWDINKRGVEETAAECR-KLGVTAHAYVVD 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 384
++ E LN V +E G + +V+NNA L++ K EVN+ T
Sbjct: 94 CSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITK 153
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTG 561
+ M + + G ++ V+SV + Y ++K A + F + + KTG
Sbjct: 154 ALLPSMMERNHGH---IVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 562 VRVLTVC 582
++ +C
Sbjct: 211 IKTSCLC 217
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 44.8 bits (101), Expect = 3e-04
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG G+G ++ + L + G A + E G + EL + + D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFA--GVLNENGPGAE-ELRRTCSPRLSVLQMDI 139
Query: 226 TDEEHFLGILN--AVVQEQGGIDVVINNAALM---NDS----IGIYKKAIEVNVTALITS 378
T + A + + G+ VINNA ++ D + YK+ + VN +
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T + ++ K G ++NVSS+ + Y ++K+AV FS+ + R E SK
Sbjct: 200 TKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSS-VMRLE-LSKW 253
Query: 559 GVRVLTVCFGATDTALLTDEKLGTFDKY--LESSCLDQL 669
G++V ++ G T + GT DK+ LE LD L
Sbjct: 254 GIKVASIQPGGFLTNI-----AGTSDKWEKLEKDILDHL 287
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 44.8 bits (101), Expect = 3e-04
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG G+G ++ + L + G A + E G + EL + + D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFA--GVLNENGPGAE-ELRRTCSPRLSVLQMDI 139
Query: 226 TDEEHFLGILN--AVVQEQGGIDVVINNAALM---NDS----IGIYKKAIEVNVTALITS 378
T + A + + G+ VINNA ++ D + YK+ + VN +
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T + ++ K G ++NVSS+ + Y ++K+AV FS+ + R E SK
Sbjct: 200 TKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSS-VMRLE-LSKW 253
Query: 559 GVRVLTVCFGATDTALLTDEKLGTFDKY--LESSCLDQL 669
G++V ++ G T + GT DK+ LE LD L
Sbjct: 254 GIKVASIQPGGFLTNI-----AGTSDKWEKLEKDILDHL 287
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 8/187 (4%)
Frame = +1
Query: 46 KVVFITGAATGIG-ESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V ITGA GIG ++ + + + + DI + + AE K G Y D
Sbjct: 37 EIVLITGAGHGIGRQTTYEFAKRQSI--LVLWDINKRGVEETAAECR-KLGVTAHAYVVD 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 384
++ E LN V +E G + +V+NNA L++ K EVN+ T
Sbjct: 94 CSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITK 153
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTG 561
+ M + + G ++ V+SV + Y ++K A + F + + KTG
Sbjct: 154 ALLPSMMERNHGH---IVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 562 VRVLTVC 582
++ +C
Sbjct: 211 IKTSCLC 217
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 44.8 bits (101), Expect = 3e-04
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG G+G ++ + L + G A + E G + EL + + D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFA--GVLNENGPGAE-ELRRTCSPRLSVLQMDI 139
Query: 226 TDEEHFLGILN--AVVQEQGGIDVVINNAALM---NDS----IGIYKKAIEVNVTALITS 378
T + A + + G+ VINNA ++ D + YK+ + VN +
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T + ++ K G ++NVSS+ + Y ++K+AV FS+ + R E SK
Sbjct: 200 TKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSS-VMRLE-LSKW 253
Query: 559 GVRVLTVCFGATDTALLTDEKLGTFDKY--LESSCLDQL 669
G++V ++ G T + GT DK+ LE LD L
Sbjct: 254 GIKVASIQPGGFLTNI-----AGTSDKWEKLEKDILDHL 287
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 8/187 (4%)
Frame = +1
Query: 46 KVVFITGAATGIG-ESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V ITGA GIG ++ + + + + DI + + AE K G Y D
Sbjct: 37 EIVLITGAGHGIGRQTTYEFAKRQSI--LVLWDINKRGVEETAAECR-KLGVTAHAYVVD 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 384
++ E LN V +E G + +V+NNA L++ K EVN+ T
Sbjct: 94 CSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITK 153
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTG 561
+ M + + G ++ V+SV + Y ++K A + F + + KTG
Sbjct: 154 ALLPSMMERNHGH---IVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 562 VRVLTVC 582
++ +C
Sbjct: 211 IKTSCLC 217
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 8/187 (4%)
Frame = +1
Query: 46 KVVFITGAATGIG-ESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V ITGA GIG ++ + + + + DI + + AE K G Y D
Sbjct: 37 EIVLITGAGHGIGRQTTYEFAKRQSI--LVLWDINKRGVEETAAECR-KLGVTAHAYVVD 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 384
++ E LN V +E G + +V+NNA L++ K EVN+ T
Sbjct: 94 CSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITK 153
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTG 561
+ M + + G ++ V+SV + Y ++K A + F + + KTG
Sbjct: 154 ALLPSMMERNHGH---IVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 562 VRVLTVC 582
++ +C
Sbjct: 211 IKTSCLC 217
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 44.8 bits (101), Expect = 3e-04
Identities = 57/219 (26%), Positives = 96/219 (43%), Gaps = 11/219 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG G+G ++ + L + G A + E G + EL + + D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFA--GVLNENGPGAE-ELRRTCSPRLSVLQMDI 139
Query: 226 TDEEHFLGILN--AVVQEQGGIDVVINNAALM---NDS----IGIYKKAIEVNVTALITS 378
T + A + + G+ VINNA ++ D + YK+ + VN +
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 379 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 558
T + ++ K G ++NVSS+ + Y ++K+AV FS+ + R E SK
Sbjct: 200 TKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSS-VMRLE-LSKW 253
Query: 559 GVRVLTVCFGATDTALLTDEKLGTFDKY--LESSCLDQL 669
G++V ++ G T + GT DK+ LE LD L
Sbjct: 254 GIKVASIQPGGFLTNI-----AGTSDKWEKLEKDILDHL 287
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 8/187 (4%)
Frame = +1
Query: 46 KVVFITGAATGIG-ESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V ITGA GIG ++ + + + + DI + + AE K G Y D
Sbjct: 37 EIVLITGAGHGIGRQTTYEFAKRQSI--LVLWDINKRGVEETAAECR-KLGVTAHAYVVD 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 384
++ E LN V +E G + +V+NNA L++ K EVN+ T
Sbjct: 94 CSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITK 153
Query: 385 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTG 561
+ M + + G ++ V+SV + Y ++K A + F + + KTG
Sbjct: 154 ALLPSMMERNHGH---IVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 562 VRVLTVC 582
++ +C
Sbjct: 211 IKTSCLC 217
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 99
Query: 232 EEHFLGILNAVVQEQGGIDVVINNAALMN 318
E AV ++ G I +++NNAA+++
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVH 128
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 99
Query: 232 EEHFLGILNAVVQEQGGIDVVINNAALMN 318
E AV ++ G I +++NNAA+++
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVH 128
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 99
Query: 232 EEHFLGILNAVVQEQGGIDVVINNAALMN 318
E AV ++ G I +++NNAA+++
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVH 128
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 99
Query: 232 EEHFLGILNAVVQEQGGIDVVINNAALMN 318
E AV ++ G I +++NNAA+++
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVH 128
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 99
Query: 232 EEHFLGILNAVVQEQGGIDVVINNAALMN 318
E AV ++ G I +++NNAA+++
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVH 128
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 99
Query: 232 EEHFLGILNAVVQEQGGIDVVINNAALMN 318
E AV ++ G I +++NNAA+++
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVH 128
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 80/186 (43%), Gaps = 7/186 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA +G+G + G + + DI +E + + + Y D
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLG-SVLVLWDINKEGNEETCKMAREAGATRVRAYTCDC 99
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 387
+ +E + + V +E G + ++INNA ++ + +K+ +VN A + T K
Sbjct: 100 SQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW-TYK 158
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK-TGV 564
A + G ++ +SS A L+ + + Y A+K A F+ + K G+
Sbjct: 159 A--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 565 RVLTVC 582
+ VC
Sbjct: 217 KTTIVC 222
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 43.6 bits (98), Expect = 7e-04
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 256 NAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSG 417
+A+ + G+D+ INNA L++ S +K VNV AL T +A + M K
Sbjct: 3 SAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSM-KERN 61
Query: 418 GKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGA 591
G +IN++S++ + V Y ATK AV + + + ++T +R + G
Sbjct: 62 VDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGV 121
Query: 592 TDT 600
+T
Sbjct: 122 VET 124
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/186 (22%), Positives = 79/186 (42%), Gaps = 7/186 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA +G+G + G + + DI +E + + Y D
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLG-SVLVLWDINKEGNEETCKMAREAGATRVHAYTCDC 99
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 387
+ +E + + V +E G + ++INNA ++ + +K+ +VN A + T K
Sbjct: 100 SQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW-TYK 158
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK-TGV 564
A + G ++ +SS A L+ + + Y A+K A F+ + K G+
Sbjct: 159 A--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 565 RVLTVC 582
+ VC
Sbjct: 217 KTTIVC 222
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/186 (22%), Positives = 79/186 (42%), Gaps = 7/186 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA +G+G + G + + DI +E + + Y D
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLG-SVLVLWDINKEGNEETCKMAREAGATRVHAYTCDC 99
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 387
+ +E + + V +E G + ++INNA ++ + +K+ +VN A + T K
Sbjct: 100 SQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW-TYK 158
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK-TGV 564
A + G ++ +SS A L+ + + Y A+K A F+ + K G+
Sbjct: 159 A--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 565 RVLTVC 582
+ VC
Sbjct: 217 KTTIVC 222
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 43.6 bits (98), Expect = 7e-04
Identities = 52/224 (23%), Positives = 97/224 (43%), Gaps = 12/224 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG +G G S+ + L +G A + ++ G EL+S ++ + + +V
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 226 TDEEHFLGILNAVVQE----QGGIDVVINNAALMN------DSIGIYKKAIEVNVTALIT 375
E ++ V + G+ ++NNA + S+ YK+ EVN+ +
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
T + ++ + G V+N+SS+ + Y TK V FS+C+ R E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCL-RYEMY-P 228
Query: 556 TGVRVLTVCFG--ATDTALLTDEKLGTFDKYLESSCLDQLKKGF 681
GV+V V G T+L + E + K + + ++K +
Sbjct: 229 LGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDY 272
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 43.6 bits (98), Expect = 7e-04
Identities = 52/224 (23%), Positives = 97/224 (43%), Gaps = 12/224 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG +G G S+ + L +G A + ++ G EL+S ++ + + +V
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 226 TDEEHFLGILNAVVQE----QGGIDVVINNAALMN------DSIGIYKKAIEVNVTALIT 375
E ++ V + G+ ++NNA + S+ YK+ EVN+ +
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
T + ++ + G V+N+SS+ + Y TK V FS+C+ R E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCL-RYEMY-P 228
Query: 556 TGVRVLTVCFG--ATDTALLTDEKLGTFDKYLESSCLDQLKKGF 681
GV+V V G T+L + E + K + + ++K +
Sbjct: 229 LGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDY 272
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 43.6 bits (98), Expect = 7e-04
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V +TG+ +GIG ++ R L +G H+ I ++ A+L + G
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGA-HVVISSRKQQNVDRAMAKLQGE-GLSVAGIVCH 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA---LMNDSIGIYKKAIEVNVTALITSTLKAI 393
V E ++ ++ GG+D ++ +A L+ ++G ++ + ++ + S +
Sbjct: 94 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLL 153
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
+ + + G VI VSSVAA + +Y +K+A+L
Sbjct: 154 SQLLPYMENRRGAVILVSSVAAYNPVVALGVYSVSKTALL 193
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/186 (22%), Positives = 79/186 (42%), Gaps = 7/186 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA +G+G + G + + DI +E + + Y D
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLG-SVLVLWDINKEGNEETCKMAREAGATRVHAYTCDC 99
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 387
+ +E + + V +E G + ++INNA ++ + +K+ +VN A + T K
Sbjct: 100 SQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW-TYK 158
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK-TGV 564
A + G ++ +SS A L+ + + Y A+K A F+ + K G+
Sbjct: 159 A--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 565 RVLTVC 582
+ VC
Sbjct: 217 KTTIVC 222
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 43.6 bits (98), Expect = 7e-04
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 256 NAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSG 417
+A+ + G+D+ INNA L++ S +K VNV AL T +A + M K
Sbjct: 3 SAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSM-KERN 61
Query: 418 GKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGA 591
G +IN++S++ + V Y ATK AV + + + ++T +R + G
Sbjct: 62 VDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGV 121
Query: 592 TDT 600
+T
Sbjct: 122 VET 124
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 43.6 bits (98), Expect = 7e-04
Identities = 48/224 (21%), Positives = 89/224 (39%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E V E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQK 255
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRIL--LDEGVKHIAILDIA--EEAGQSLQAELNSKYGNKTKFYR 216
V +TG GIG ++VR L L G + D+ + A Q LQAE G +F++
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-----GLSPRFHQ 61
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
D+ D + + + + +E GG+DV++NNA +
Sbjct: 62 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 43.2 bits (97), Expect = 0.001
Identities = 56/208 (26%), Positives = 95/208 (45%), Gaps = 9/208 (4%)
Frame = +1
Query: 25 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 204
+SH +DK VFITG +G G+ + R L G++ +A + E+ + L+ + + + T
Sbjct: 24 LSH-LRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDRLETVT 81
Query: 205 KFYRSDVTDEEHFLGILNAVVQ--EQGGIDVVINNAALM-----NDSI--GIYKKAIEVN 357
DVT E V + G+ ++NNA + N+ + + ++VN
Sbjct: 82 ----LDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVN 137
Query: 358 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 537
+ +I TL + ++ K G V+NVSSV S Y +K V FS+ + R
Sbjct: 138 LLGVIDVTLSLLPLVRK----ARGRVVNVSSVMGRV-SLFGGGYCISKYGVEAFSDSLRR 192
Query: 538 PEHFSKTGVRVLTVCFGATDTALLTDEK 621
S GV+V + G TA+ + E+
Sbjct: 193 --ELSYFGVKVAMIEPGYFKTAVTSKER 218
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSL-----QAELNSKYGNKTKFYR 216
VFITGA+ GIG+++ +G + A+ + L AE G K
Sbjct: 13 VFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCI 72
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN 318
DV DE+ + +++ GGID+++NNA+ ++
Sbjct: 73 VDVRDEQQISAAVEKAIKKFGGIDILVNNASAIS 106
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSL-----QAELNSKYGNKTKFYR 216
VFITGA+ GIG+++ +G + A+ + L AE G K
Sbjct: 13 VFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCI 72
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN 318
DV DE+ + +++ GGID+++NNA+ ++
Sbjct: 73 VDVRDEQQISAAVEKAIKKFGGIDILVNNASAIS 106
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSL-----QAELNSKYGNKTKFYR 216
VFITGA+ GIG+++ +G + A+ + L AE G K
Sbjct: 13 VFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCI 72
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN 318
DV DE+ + +++ GGID+++NNA+ ++
Sbjct: 73 VDVRDEQQISAAVEKAIKKFGGIDILVNNASAIS 106
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/160 (21%), Positives = 75/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V +TG+ +GIG ++ R L +G H+ I ++ A+L + G
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGA-HVVISSRKQQNVDRAMAKLQGE-GLSVAGIVCH 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA---LMNDSIGIYKKAIEVNVTALITSTLKAI 393
V E ++ ++ GG+D ++ +A L+ ++G ++ + ++ + S +
Sbjct: 94 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 153
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
+ + + G VI VSS+AA + +Y +K+A+L
Sbjct: 154 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALL 193
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 42.3 bits (95), Expect = 0.002
Identities = 51/224 (22%), Positives = 97/224 (43%), Gaps = 12/224 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG +G G ++ + L +G A + ++ G EL+S ++ + + +V
Sbjct: 56 KAVLVTGCDSGFGFALAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 226 TDEEHFLGILNAVVQE----QGGIDVVINNAALMN------DSIGIYKKAIEVNVTALIT 375
E ++ V + G+ ++NNA + S+ YK+ EVN+ +
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
T + ++ + G V+N+SS+ + Y TK V FS+C+ R E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCL-RYEMY-P 228
Query: 556 TGVRVLTVCFG--ATDTALLTDEKLGTFDKYLESSCLDQLKKGF 681
GV+V V G T+L + E + K + + ++K +
Sbjct: 229 LGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDY 272
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/160 (21%), Positives = 75/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V +TG+ +GIG ++ R L +G H+ I ++ A+L + G
Sbjct: 27 NRVAVVTGSTSGIGFAIARRLARDGA-HVVISSRKQQNVDRAMAKLQGE-GLSVAGIVCH 84
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA---LMNDSIGIYKKAIEVNVTALITSTLKAI 393
V E ++ ++ GG+D ++ +A L+ ++G ++ + ++ + S +
Sbjct: 85 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 144
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
+ + + G VI VSS+AA + +Y +K+A+L
Sbjct: 145 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALL 184
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/160 (21%), Positives = 75/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V +TG+ +GIG ++ R L +G H+ I ++ A+L + G
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGA-HVVISSRKQQNVDRAMAKLQGE-GLSVAGIVCH 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA---LMNDSIGIYKKAIEVNVTALITSTLKAI 393
V E ++ ++ GG+D ++ +A L+ ++G ++ + ++ + S +
Sbjct: 94 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 153
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
+ + + G VI VSS+AA + +Y +K+A+L
Sbjct: 154 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALL 193
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
+V F+TG ATGIG+++V+ LL+ G + L+ + A LQA L + +
Sbjct: 19 QVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINN 303
++ +EE ++ + + G I+ ++NN
Sbjct: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNN 107
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 42.3 bits (95), Expect = 0.002
Identities = 35/160 (21%), Positives = 75/160 (46%), Gaps = 3/160 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSD 222
++V +TG+ +GIG ++ R L +G H+ I ++ A+L + G
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGA-HVVISSRKQQNVDRAMAKLQGE-GLSVAGIVCH 93
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAA---LMNDSIGIYKKAIEVNVTALITSTLKAI 393
V E ++ ++ GG+D ++ +A L+ ++G ++ + ++ + S +
Sbjct: 94 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 153
Query: 394 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 513
+ + + G VI VSS+AA + +Y +K+A+L
Sbjct: 154 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALL 193
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 41.1 bits (92), Expect = 0.004
Identities = 52/224 (23%), Positives = 98/224 (43%), Gaps = 12/224 (5%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
K V +TG +G G S+ + L +G A + ++ G EL+S ++ + + +V
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 226 TDEEHFLGIL-NAVVQEQG---GIDVVINNAALMN------DSIGIYKKAIEVNVTALIT 375
E ++ + + +G G+ ++NNA + S+ YK+ EVN+ +
Sbjct: 115 FRSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 555
T + ++ + G V+N+SS+ + Y TK V FS+C+ R E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCL-RYEMY-P 228
Query: 556 TGVRVLTVCFG--ATDTALLTDEKLGTFDKYLESSCLDQLKKGF 681
GV+V V G T+L E + K + + ++K +
Sbjct: 229 LGVKVSVVEPGNFIAATSLYNPESIQAIAKKMWEELPEVVRKDY 272
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/139 (22%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
+V +TG ATGIG+++V+ LL+ G + L+ + A LQA L + +
Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKA 390
++ +EE ++ + + G I+ ++NN ++ + I K + +T T
Sbjct: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138
Query: 391 IE-IMGKHSGGKGGTVINV 444
+ + GG+++N+
Sbjct: 139 CKAVYSSWMKEHGGSIVNI 157
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/139 (22%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
+V +TG ATGIG+++V+ LL+ G + L+ + A LQA L + +
Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKA 390
++ +EE ++ + + G I+ ++NN ++ + I K + +T T
Sbjct: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138
Query: 391 IE-IMGKHSGGKGGTVINV 444
+ + GG+++N+
Sbjct: 139 CKAVYSSWMKEHGGSIVNI 157
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/139 (22%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
+V +TG ATGIG+++V+ LL+ G + L+ + A LQA L + +
Sbjct: 38 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 97
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKA 390
++ +EE ++ + + G I+ ++NN ++ + I K + +T T
Sbjct: 98 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 157
Query: 391 IE-IMGKHSGGKGGTVINV 444
+ + GG+++N+
Sbjct: 158 CKAVYSSWMKEHGGSIVNI 176
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/139 (22%), Positives = 64/139 (46%), Gaps = 6/139 (4%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
+V +TG ATGIG+++V+ LL+ G + L+ + A LQA L + +
Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQ 78
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKA 390
++ +EE ++ + + G I+ ++NN ++ + I K + +T T
Sbjct: 79 CNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYM 138
Query: 391 IE-IMGKHSGGKGGTVINV 444
+ + GG+++N+
Sbjct: 139 CKAVYSSWMKEHGGSIVNI 157
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 40.7 bits (91), Expect = 0.005
Identities = 48/190 (25%), Positives = 85/190 (44%), Gaps = 10/190 (5%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DK VFITG +G G + R L G++ +A + E+ + L+ + + + T
Sbjct: 28 QDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDRLETVT----L 82
Query: 220 DVTDEEHFLGILNAVVQEQG--GIDVVINNAALMND-------SIGIYKKAIEVNVTALI 372
DVT E V + G G+ ++NNA ++ + ++VN+ +I
Sbjct: 83 DVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVI 142
Query: 373 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP-EHF 549
TL + ++ + G ++NVSS+ V Y +K V FS+ + R +HF
Sbjct: 143 QVTLSMLPLVRR----ARGRIVNVSSILGRVAFFVGG-YCVSKYGVEAFSDILRREIQHF 197
Query: 550 SKTGVRVLTV 579
GV++ V
Sbjct: 198 ---GVKISIV 204
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 40.7 bits (91), Expect = 0.005
Identities = 48/190 (25%), Positives = 85/190 (44%), Gaps = 10/190 (5%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DK VFITG +G G + R L G++ +A + E+ + L+ + + + T
Sbjct: 28 QDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDRLETVT----L 82
Query: 220 DVTDEEHFLGILNAVVQEQG--GIDVVINNAALMND-------SIGIYKKAIEVNVTALI 372
DVT E V + G G+ ++NNA ++ + ++VN+ +I
Sbjct: 83 DVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVI 142
Query: 373 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP-EHF 549
TL + ++ + G ++NVSS+ V Y +K V FS+ + R +HF
Sbjct: 143 QVTLSMLPLVRR----ARGRIVNVSSILGRVAFFVGG-YCVSKYGVEAFSDILRREIQHF 197
Query: 550 SKTGVRVLTV 579
GV++ V
Sbjct: 198 ---GVKISIV 204
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 40.7 bits (91), Expect = 0.005
Identities = 48/190 (25%), Positives = 85/190 (44%), Gaps = 10/190 (5%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DK VFITG +G G + R L G++ +A + E+ + L+ + + + T
Sbjct: 28 QDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDRLETVT----L 82
Query: 220 DVTDEEHFLGILNAVVQEQG--GIDVVINNAALMND-------SIGIYKKAIEVNVTALI 372
DVT E V + G G+ ++NNA ++ + ++VN+ +I
Sbjct: 83 DVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVI 142
Query: 373 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP-EHF 549
TL + ++ + G ++NVSS+ V Y +K V FS+ + R +HF
Sbjct: 143 QVTLSMLPLVRR----ARGRIVNVSSILGRVAFFVGG-YCVSKYGVEAFSDILRREIQHF 197
Query: 550 SKTGVRVLTV 579
GV++ V
Sbjct: 198 ---GVKISIV 204
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 39.9 bits (89), Expect = 0.009
Identities = 47/224 (20%), Positives = 87/224 (38%), Gaps = 7/224 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDV 225
++V ITGA GIG K + + DI + + A+ G K + D
Sbjct: 37 EIVLITGAGHGIGRLTAYEFAKLKSK-LVLWDINKHGLEETAAKCKG-LGAKVHTFVVDC 94
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 387
++ E E G + +++NNA ++ +D +K EVNV A +T
Sbjct: 95 SNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKA 154
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI-GRPEHFSKTGV 564
+ M K++ G ++ V+S A + Y ++K A + F + TGV
Sbjct: 155 FLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 565 RVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRK 696
+ +C +T + +++L G + ++K
Sbjct: 212 KTTCLCPNFVNTGFIKKMSTSLGPTLEPEEVVNRLMHGILTEQK 255
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 39.1 bits (87), Expect = 0.016
Identities = 43/142 (30%), Positives = 68/142 (47%), Gaps = 4/142 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ N V + +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAA 459
+ K K G +IN+SSVA+
Sbjct: 115 AFLPKMLAQKSGNIINMSSVAS 136
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 39.1 bits (87), Expect = 0.016
Identities = 26/90 (28%), Positives = 41/90 (45%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DKV FITG +GIG + I + G H I + + +L G +
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAA 309
DV + ++ ++E G ID++IN AA
Sbjct: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA 115
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 39.1 bits (87), Expect = 0.016
Identities = 26/90 (28%), Positives = 41/90 (45%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DKV FITG +GIG + I + G H I + + +L G +
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAA 309
DV + ++ ++E G ID++IN AA
Sbjct: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA 115
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 39.1 bits (87), Expect = 0.016
Identities = 43/142 (30%), Positives = 68/142 (47%), Gaps = 4/142 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ N V + +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQIDQFANEVER----LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAA 459
+ K K G +IN+SSVA+
Sbjct: 115 AFLPKMLAQKSGNIINMSSVAS 136
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 39.1 bits (87), Expect = 0.016
Identities = 26/90 (28%), Positives = 41/90 (45%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DKV FITG +GIG + I + G H I + + +L G +
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAA 309
DV + ++ ++E G ID++IN AA
Sbjct: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA 115
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 39.1 bits (87), Expect = 0.016
Identities = 26/90 (28%), Positives = 41/90 (45%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DKV FITG +GIG + I + G H I + + +L G +
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAA 309
DV + ++ ++E G ID++IN AA
Sbjct: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA 115
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 38.7 bits (86), Expect = 0.021
Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 4/142 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKY-GNKTKFYRSD 222
KV+ +T AA GIG++ EG K IA DI E Q L+ KY G +T+ D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELE-----KYPGIQTRVL--D 58
Query: 223 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIE 396
VT ++ ++ E +DV+ N A ++ + +K + ++ + S I+
Sbjct: 59 VTKKKQ----IDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 397 -IMGKHSGGKGGTVINVSSVAA 459
+ K K G +IN+SSVA+
Sbjct: 115 AFLPKMLAQKSGNIINMSSVAS 136
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 38.7 bits (86), Expect = 0.021
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIAARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 9 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 60
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 61 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 114
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 115 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 155
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 38.3 bits (85), Expect = 0.027
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 4 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 62
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 63 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDK 122
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 123 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 180
Query: 523 NCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 648
R + G+R +V G T + DK E
Sbjct: 181 QTAAR--ELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE 220
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 38.3 bits (85), Expect = 0.027
Identities = 36/163 (22%), Positives = 72/163 (44%), Gaps = 5/163 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--QSLQAELNSKYGNKTKFYRS 219
+ V I+G ++GIG + L + K ++ + G ++L+A G +
Sbjct: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQL 65
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAIEVNVTALITSTLKAI 393
DV +E L+ + QG +DV++NNA L+ G+ A++ ++ +
Sbjct: 66 DVCSDESVAQCLSCI---QGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLV 122
Query: 394 E-IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQF 519
+ ++ + G ++ +SSV L +Y A+K A+ F
Sbjct: 123 KAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGF 165
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 38.3 bits (85), Expect = 0.027
Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 9/208 (4%)
Frame = +1
Query: 25 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKT 204
+SH +DK VFITG +G G+ + R L G++ +A + E+ + L+ + + + T
Sbjct: 24 LSH-LRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDRLETVT 81
Query: 205 KFYRSDVTDEEHFLGILNAVVQ--EQGGIDVVINNAALM-----NDSIGIYK--KAIEVN 357
DVT E V + G+ ++NNA + N+ + ++VN
Sbjct: 82 ----LDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDLLTILDVN 137
Query: 358 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 537
+ +I TL + ++ + G V+NV SV S Y +K V FS+ + R
Sbjct: 138 LLGVIDVTLNLLPLVRR----ARGRVVNVFSVMGRV-SLFGGGYCISKYGVEAFSDSLRR 192
Query: 538 PEHFSKTGVRVLTVCFGATDTALLTDEK 621
S GV+V + G TA+ + E+
Sbjct: 193 --ELSYFGVKVAMIEPGYFKTAVTSKER 218
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.027
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 8/161 (4%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS--DV 225
V +TGA GIG V+ L G + +A+ QA+L+S D+
Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAV--------SRTQADLDSLVRECPGIEPVCVDL 61
Query: 226 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAI----EVNVTALITSTLK 387
D E L +V G +D+++NNAA L+ + + K+A EVN+ A+I +
Sbjct: 62 GDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQ--VS 115
Query: 388 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 510
I G + G G ++NVSS + +Y +TK A+
Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGAL 156
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 37.5 bits (83), Expect = 0.048
Identities = 26/87 (29%), Positives = 44/87 (50%)
Frame = +1
Query: 319 DSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFAT 498
D + KK I +N+ ++ T + M + S G ++N+SS + + ++ IY AT
Sbjct: 14 DLDNVIKKMININILSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSAT 70
Query: 499 KSAVLQFSNCIGRPEHFSKTGVRVLTV 579
K+ V FS C+ E + GV V +V
Sbjct: 71 KTFVDFFSQCL--HEEYRSKGVFVQSV 95
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 37.1 bits (82), Expect = 0.063
Identities = 23/75 (30%), Positives = 41/75 (54%)
Frame = +1
Query: 307 ALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 486
+LM+ + ++ K +++NV A T + M K GG +V+ VSS+AA + S
Sbjct: 1 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGG---SVVIVSSIAAFSPSPGFSP 57
Query: 487 YFATKSAVLQFSNCI 531
Y +K+A+L +N +
Sbjct: 58 YNVSKTALLGLNNTL 72
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.11
Identities = 58/235 (24%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDE-GVKHIAILDIA-EEAGQSLQAELNS-KYGNKTKFYRS 219
V +TGA+ G G ++ +L + +L +EA + L+AEL + + G + +
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68
Query: 220 DVTDE---EHFLGILNAVVQEQGGIDVV-INNAALMND-SIGIYKKAIE--------VNV 360
D+ E + LG L + + +G ++ INNA + D S G + +N+
Sbjct: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128
Query: 361 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 540
T+++ T ++ S G TV+N+SS+ AL +Y A K+A +
Sbjct: 129 TSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
Query: 541 EHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRKESA 705
E VRVL G DT + + + D + + KG + K SA
Sbjct: 188 E----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.11
Identities = 58/235 (24%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDE-GVKHIAILDIA-EEAGQSLQAELNS-KYGNKTKFYRS 219
V +TGA+ G G ++ +L + +L +EA + L+AEL + + G + +
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68
Query: 220 DVTDE---EHFLGILNAVVQEQGGIDVV-INNAALMND-SIGIYKKAIE--------VNV 360
D+ E + LG L + + +G ++ INNA + D S G + +N+
Sbjct: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128
Query: 361 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 540
T+++ T ++ S G TV+N+SS+ AL +Y A K+A +
Sbjct: 129 TSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
Query: 541 EHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRKESA 705
E VRVL G DT + + + D + + KG + K SA
Sbjct: 188 E----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 35.5 bits (78), Expect = 0.19
Identities = 44/185 (23%), Positives = 77/185 (41%), Gaps = 13/185 (7%)
Frame = +1
Query: 22 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQS---LQAELNSKY 192
++ + + + +TGA +GIG +V L EG +A D+ A Q L SK
Sbjct: 2 QLQNRLRSALALVTGAGSGIGRAVSVRLAGEGAT-VAACDLDRAAAQETVRLLGGPGSKE 60
Query: 193 G---NKTKFYRSDVTDEEHFLGILNAV-VQEQGGIDVVINNAALMNDSIGI------YKK 342
G +++DV++ +L V VV++ A + D + + K
Sbjct: 61 GPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDK 120
Query: 343 AIEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 522
I VN+ T A + + S G G++IN+SS+ + Y A+K+ V+ +
Sbjct: 121 VIAVNLKGTFLVTQAAAQAL--VSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT 178
Query: 523 NCIGR 537
R
Sbjct: 179 QTAAR 183
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 35.5 bits (78), Expect = 0.19
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
K V +TGA TGIG+ L G I ++ E A + ++ E + + N
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDL 98
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
+ + F +++E+ +D++INNA +M
Sbjct: 99 ASLKSIREFAA---KIIEEEERVDILINNAGVM 128
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 35.5 bits (78), Expect = 0.19
Identities = 58/235 (24%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDE-GVKHIAILDIA-EEAGQSLQAELNS-KYGNKTKFYRS 219
V +TGA+ G G ++ +L + +L +EA + L+AEL + + G + +
Sbjct: 9 VRLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68
Query: 220 DVTDE---EHFLGILNAVVQEQGGIDVV-INNAALMND-SIGIYKKAIE--------VNV 360
D+ E + LG L + + +G ++ INNA + D S G + +N+
Sbjct: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128
Query: 361 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 540
T+++ T ++ S G TV+N+SS+ AL +Y A K+A +
Sbjct: 129 TSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
Query: 541 EHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFIFQRKESA 705
E VRVL G DT + + + D + + KG + K SA
Sbjct: 188 E----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238
>AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retinol
dehydrogenase A2 isoform protein.
Length = 188
Score = 34.7 bits (76), Expect = 0.34
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 88
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
+ D E + V+ GGID++++NAA+
Sbjct: 89 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAV 119
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 34.7 bits (76), Expect = 0.34
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI----AEEAGQSLQAELNSKYGNKTKF 210
+KV +T + GIG ++ R L +G H+ + ++A +LQ E S G T
Sbjct: 14 NKVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQNVDQAVATLQGEGLSVTG--TVC 70
Query: 211 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 312
+ D E + V+ GGID++++NAA+
Sbjct: 71 HVGKAEDRERLVA---TAVKLHGGIDILVSNAAV 101
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 34.7 bits (76), Expect = 0.34
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGQSLQAELNSKYGNKTKFYR 216
K V +TGA TGIG+ L G I ++ E A + ++ E + + N
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHL-- 96
Query: 217 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + +++E+ +D++INNA +M
Sbjct: 97 -DLASLKSIRVFAAKIIEEEERVDILINNAGVM 128
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 33.5 bits (73), Expect = 0.78
Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 16/169 (9%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDE-GVKHIAILDIA-EEAGQSLQAELNS-KYGNKTKFYRS 219
V +TGA+ G G ++ +L + +L +EA + L+AEL + + G + +
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68
Query: 220 DVTDE---EHFLGILNAVVQEQGGIDVV-INNAALMND-SIGIYKKAIE--------VNV 360
D+ E + LG L + + +G ++ INNA + D S G + +N+
Sbjct: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128
Query: 361 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSA 507
T+++ T ++ S G TV+N+SS+ AL +Y A K+A
Sbjct: 129 TSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAA 176
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 33.5 bits (73), Expect = 0.78
Identities = 44/169 (26%), Positives = 79/169 (46%), Gaps = 16/169 (9%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDE-GVKHIAILDIA-EEAGQSLQAELNS-KYGNKTKFYRS 219
V +TGA+ G G ++ +L + +L +EA + L+AEL + + G + +
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68
Query: 220 DVTDE---EHFLGILNAVVQEQGGIDVV-INNAALMND-SIGIYKKAIE--------VNV 360
D+ E + LG L + + +G ++ INNA + D S G + +N+
Sbjct: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128
Query: 361 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSA 507
T+++ T ++ S G TV+N+SS+ AL +Y A K+A
Sbjct: 129 TSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAA 176
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 32.3 bits (70), Expect = 1.8
Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE---------AGQSLQAELNSKYGN 198
+VV +TGA G+G + + G + + D+ + A + E+ + G
Sbjct: 10 RVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK 68
Query: 199 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALI 372
Y S E+ ++ + G IDVV+NNA ++ D I + ++ +
Sbjct: 69 AVANYDSVEEGEK----VVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
Query: 373 TSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ + +H K G +I SS + + + Y A K +L +N +
Sbjct: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
>M77144-1|AAA36014.1| 372|Homo sapiens 3-beta-hydroxysteroid
dehydrogenase/delta-5-delta-4 isomerase type II protein.
Length = 372
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>M67466-1|AAA36016.1| 372|Homo sapiens 3-beta-hydroxysteroid
dehydrogenase/delta-5-4-isomerase protein.
Length = 372
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 120 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 178
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 179 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 210
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 120 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 178
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 179 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 210
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC131488-1|AAI31489.1| 372|Homo sapiens HSD3B2 protein protein.
Length = 372
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>BC038419-1|AAH38419.1| 372|Homo sapiens hydroxy-delta-5-steroid
dehydrogenase, 3 beta- and steroid delta-isomerase 2
protein.
Length = 372
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC007230-1|AAH07230.1| 494|Homo sapiens COCH protein protein.
Length = 494
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/119 (19%), Positives = 54/119 (45%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 228
+ F+ ++ +G+S R++L E V +IA + G + A + Y +T+F +D +
Sbjct: 368 IAFLIDGSSSVGDSNFRLML-EFVSNIAKTFEISDIGAKIAA-VQFTYDQRTEFSFTDYS 425
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 405
+E+ L ++ + GG + + + G +++ N ++T ++ G
Sbjct: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQG 484
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 32.3 bits (70), Expect = 1.8
Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE---------AGQSLQAELNSKYGN 198
+VV +TGA G+G + + G + + D+ + A + E+ + G
Sbjct: 10 RVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK 68
Query: 199 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALI 372
Y S E+ ++ + G IDVV+NNA ++ D I + ++ +
Sbjct: 69 AVANYDSVEEGEK----VVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
Query: 373 TSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ + +H K G +I SS + + + Y A K +L +N +
Sbjct: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
>AY916789-1|AAW82432.1| 550|Homo sapiens coagulation factor C
homolog, cochlin (Limulus polyphemus) protein.
Length = 550
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/119 (19%), Positives = 54/119 (45%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 228
+ F+ ++ +G+S R++L E V +IA + G + A + Y +T+F +D +
Sbjct: 368 IAFLIDGSSSVGDSNFRLML-EFVSNIAKTFEISDIGAKIAA-VQFTYDQRTEFSFTDYS 425
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 405
+E+ L ++ + GG + + + G +++ N ++T ++ G
Sbjct: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQG 484
>AY358900-1|AAQ89259.1| 550|Homo sapiens COCH protein.
Length = 550
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/119 (19%), Positives = 54/119 (45%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 228
+ F+ ++ +G+S R++L E V +IA + G + A + Y +T+F +D +
Sbjct: 368 IAFLIDGSSSVGDSNFRLML-EFVSNIAKTFEISDIGAKIAA-VQFTYDQRTEFSFTDYS 425
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 405
+E+ L ++ + GG + + + G +++ N ++T ++ G
Sbjct: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQG 484
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>AL359553-5|CAC19799.1| 372|Homo sapiens hydroxy-delta-5-steroid
dehydrogenase, 3 beta-ande) protein.
Length = 372
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>AL359553-4|CAI23079.1| 195|Homo sapiens hydroxy-delta-5-steroid
dehydrogenase, 3 beta-andRNA helicase) (DDH10) pseudoge
protein.
Length = 195
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>AK222997-1|BAD96717.1| 372|Homo sapiens hydroxy-delta-5-steroid
dehydrogenase, 3 beta- and steroid delta-isomerase 2 va
protein.
Length = 372
Score = 32.3 bits (70), Expect = 1.8
Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = +1
Query: 58 ITGAATGIGESVVRILLDE-GVKHIAILDIAEEAGQSLQAELNSKYGNKTKF--YRSDVT 228
+TGA +G+ +VR+L++E +K I LD A L+ E SK N+TK D+
Sbjct: 7 VTGAGGLLGQRIVRLLVEEKELKEIRALDKAFR--PELREEF-SKLQNRTKLTVLEGDIL 63
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 384
DE L Q+ + VVI+ A ++ D G+ + +NV T L
Sbjct: 64 DEP----FLKRACQD---VSVVIHTACII-DVFGVTHRESIMNVNVKGTQLL 107
>AK130273-1|BAC85316.1| 401|Homo sapiens protein ( Homo sapiens
cDNA FLJ26763 fis, clone PRS02632, highly similar to
COCHLIN PRECURSOR. ).
Length = 401
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/119 (19%), Positives = 54/119 (45%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 228
+ F+ ++ +G+S R++L E V +IA + G + A + Y +T+F +D +
Sbjct: 219 IAFLIDGSSSVGDSNFRLML-EFVSNIAKTFEISDIGAKIAA-VQFTYDQRTEFSFTDYS 276
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 405
+E+ L ++ + GG + + + G +++ N ++T ++ G
Sbjct: 277 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQG 335
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 32.3 bits (70), Expect = 1.8
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
D+V +TG GIG S + L G+ H+ I + + + +++ + N K +F
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYC 101
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
D+ + ++ + V+INNA +M
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 32.3 bits (70), Expect = 1.8
Identities = 36/174 (20%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Frame = +1
Query: 46 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE---------AGQSLQAELNSKYGN 198
+VV +TGA G+G + + G + + D+ + A + E+ + G
Sbjct: 10 RVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK 68
Query: 199 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALI 372
Y S E+ ++ + G IDVV+NNA ++ D I + ++ +
Sbjct: 69 AVANYDSVEEGEK----VVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
Query: 373 TSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 531
+ + +H K G +I SS + + + Y A K +L +N +
Sbjct: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
>AF006740-1|AAC39545.1| 550|Homo sapiens Coch-5B2 protein.
Length = 550
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/119 (19%), Positives = 54/119 (45%)
Frame = +1
Query: 49 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVT 228
+ F+ ++ +G+S R++L E V +IA + G + A + Y +T+F +D +
Sbjct: 368 IAFLIDGSSSVGDSNFRLML-EFVSNIAKTFEISDIGAKIAA-VQFTYDQRTEFSFTDYS 425
Query: 229 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 405
+E+ L ++ + GG + + + G +++ N ++T ++ G
Sbjct: 426 TKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQG 484
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 31.9 bits (69), Expect = 2.4
Identities = 16/41 (39%), Positives = 22/41 (53%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQ 162
+DKV FITG +GIG + I + G H A +A G+
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTAARKLAGATGR 66
>D50419-1|BAA23362.1| 711|Homo sapiens OTK18 protein.
Length = 711
Score = 31.1 bits (67), Expect = 4.1
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -2
Query: 588 TKAHCQYSDPGFRKVFRSTDTITELQHSAFSCEVYWHNVRLRQSGNRRNVDNCT 427
T+++C+Y DPG K+ R+ + Q C ++ +++L N +N N T
Sbjct: 169 TESNCEYKDPG--KMIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDT 220
>BC052997-1|AAH52997.1| 711|Homo sapiens zinc finger protein 175
protein.
Length = 711
Score = 31.1 bits (67), Expect = 4.1
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -2
Query: 588 TKAHCQYSDPGFRKVFRSTDTITELQHSAFSCEVYWHNVRLRQSGNRRNVDNCT 427
T+++C+Y DPG K+ R+ + Q C ++ +++L N +N N T
Sbjct: 169 TESNCEYKDPG--KMIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDT 220
>AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 223
Score = 31.1 bits (67), Expect = 4.1
Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 46 KVVFITGAATGIGESVV-RILLDEGVKHIAILDIAEEAGQSLQAELNSKYGN-KTKFYRS 219
KVV ITGA++GIG ++ R+L ++ H+ + +++ A L + + + +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM 315
DV++ + F + Q +D + NA +M
Sbjct: 63 DVSNLQSFFRASKELKQRFQRLDRIYLNAGIM 94
>AC018755-1|AAF87843.1| 711|Homo sapiens zinc finger protein 175
protein.
Length = 711
Score = 31.1 bits (67), Expect = 4.1
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = -2
Query: 588 TKAHCQYSDPGFRKVFRSTDTITELQHSAFSCEVYWHNVRLRQSGNRRNVDNCT 427
T+++C+Y DPG K+ R+ + Q C ++ +++L N +N N T
Sbjct: 169 TESNCEYKDPG--KMIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDT 220
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 30.7 bits (66), Expect = 5.5
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRS 219
+DK VFITG +G G + R L G++ +A + ++ + L+ + + + T
Sbjct: 28 QDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTDKGAEQLRGQTSDRLETVT----L 82
Query: 220 DVTDEEHFLGILNAVVQEQGGIDV--VINNAALM 315
DVT E V + G + ++NNA ++
Sbjct: 83 DVTKMESIAAATQWVKEHVGDRRLWGLVNNAGIL 116
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 29.9 bits (64), Expect = 9.6
Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Frame = +1
Query: 259 AVVQEQG-GIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGTV 435
A +Q +G + + + D + +++NV A T + M K GG +V
Sbjct: 74 ATLQGEGLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGGG---SV 130
Query: 436 INVSSVAALTQSHVMPIYFATKSAVL 513
+ VSS+AA + S Y +K+A+L
Sbjct: 131 VIVSSIAAFSPSPGFSPYNVSKTALL 156
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 29.9 bits (64), Expect = 9.6
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
Frame = +1
Query: 25 MSHEWKDKVVFITGAATGIGESVVRILLDEGV------KHIAILDIAEEAGQSLQAELNS 186
M+ +V +TGA+ GIG + L G +H+ L + + QSL
Sbjct: 1 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSL------ 54
Query: 187 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGG-IDVVINNA 306
G + D + E + V +EQ G +DV++NNA
Sbjct: 55 --GGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein.
Length = 152
Score = 29.9 bits (64), Expect = 9.6
Identities = 18/71 (25%), Positives = 30/71 (42%)
Frame = +1
Query: 52 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGQSLQAELNSKYGNKTKFYRSDVTD 231
V ITG GIG + R + G + I + E+ + E+ + G + ++ DV +
Sbjct: 26 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTECHYFICDVGN 84
Query: 232 EEHFLGILNAV 264
E AV
Sbjct: 85 REEVYQTAKAV 95
>AL023881-2|CAO77955.1| 81|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 81
Score = 29.9 bits (64), Expect = 9.6
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +1
Query: 40 KDKVVFITGAATGIGESVVRILLDEG 117
+DKV FITG +GIG + I + G
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHG 52
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 29.9 bits (64), Expect = 9.6
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
Frame = +1
Query: 25 MSHEWKDKVVFITGAATGIGESVVRILLDEGV------KHIAILDIAEEAGQSLQAELNS 186
M+ +V +TGA+ GIG + L G +H+ L + + QSL
Sbjct: 1 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSL------ 54
Query: 187 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGG-IDVVINNA 306
G + D + E + V +EQ G +DV++NNA
Sbjct: 55 --GGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 29.9 bits (64), Expect = 9.6
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 7/101 (6%)
Frame = +1
Query: 25 MSHEWKDKVVFITGAATGIGESVVRILLDEGV------KHIAILDIAEEAGQSLQAELNS 186
M+ +V +TGA+ GIG + L G +H+ L + + QSL
Sbjct: 1 MAAPMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSL------ 54
Query: 187 KYGNKTKFYRSDVTDEEHFLGILNAVVQEQGG-IDVVINNA 306
G + D + E + V +EQ G +DV++NNA
Sbjct: 55 --GGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.374
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,093,102
Number of Sequences: 237096
Number of extensions: 2118804
Number of successful extensions: 5418
Number of sequences better than 10.0: 238
Number of HSP's better than 10.0 without gapping: 5095
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5276
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8455186714
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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