Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt18i16
(576 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 130 3e-30
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 130 3e-30
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 130 3e-30
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 130 3e-30
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 130 3e-30
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 130 3e-30
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 130 3e-30
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 130 3e-30
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 130 3e-30
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 130 3e-30
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 130 3e-30
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 130 3e-30
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 130 3e-30
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 126 6e-29
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 126 6e-29
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 121 2e-27
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 117 3e-26
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 117 3e-26
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 117 3e-26
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 117 3e-26
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 117 3e-26
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 117 3e-26
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 117 3e-26
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 116 8e-26
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 93 8e-19
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 77 6e-14
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 25 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 81
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 82 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 141
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 142 YRAHGFTFTRGLSVREILAELTG 164
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 130 bits (315), Expect = 3e-30
Identities = 63/143 (44%), Positives = 92/143 (64%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 507
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 508 YRCHGWTYLMGVSVLGVLSELTG 576
YR HG+T+ G+SV +L+ELTG
Sbjct: 118 YRAHGFTFTRGLSVREILAELTG 140
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 126 bits (304), Expect = 6e-29
Identities = 57/108 (52%), Positives = 75/108 (69%)
Frame = +1
Query: 253 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 432
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 433 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTG
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTG 178
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 126 bits (304), Expect = 6e-29
Identities = 57/108 (52%), Positives = 75/108 (69%)
Frame = +1
Query: 253 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 432
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 433 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTG
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTG 178
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 121 bits (292), Expect = 2e-27
Identities = 63/150 (42%), Positives = 92/150 (61%), Gaps = 7/150 (4%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG-------QEAVAVGMRAAMRD 486
ED LK Y + +RR+E + LYK+KIIRGFCHL G QEA VG+ A +
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINP 117
Query: 487 ADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
D +ITAYR HG+T+ G+SV +L+ELTG
Sbjct: 118 TDHLITAYRAHGFTFTRGLSVREILAELTG 147
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 138
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 138
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 138
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 138
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 138
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 43 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 102
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 103 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 157
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 117 bits (281), Expect = 3e-26
Identities = 54/115 (46%), Positives = 74/115 (64%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTG 138
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 116 bits (278), Expect = 8e-26
Identities = 54/115 (46%), Positives = 73/115 (63%)
Frame = +1
Query: 232 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 411
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 412 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 576
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G SV +L+ELTG
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTG 138
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 92.7 bits (220), Expect = 8e-19
Identities = 46/110 (41%), Positives = 67/110 (60%)
Frame = +1
Query: 148 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 327
M K++ + + L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSPVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 328 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 477
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLERA 107
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 76.6 bits (180), Expect = 6e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = +1
Query: 253 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 432
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 61 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 120
Query: 433 L 435
L
Sbjct: 121 L 121
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,143,012
Number of Sequences: 237096
Number of extensions: 1445310
Number of successful extensions: 3265
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 3153
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3257
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5929224630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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