Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt18b21
(517 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 104 2e-22
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 104 2e-22
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 104 2e-22
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 104 2e-22
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 94 2e-19
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 94 2e-19
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 94 2e-19
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 93 4e-19
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 91 2e-18
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 91 2e-18
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 91 2e-18
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 91 2e-18
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 91 2e-18
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 91 2e-18
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 91 2e-18
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 91 2e-18
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 90 4e-18
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 79 1e-14
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 79 1e-14
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 79 1e-14
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 79 1e-14
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 79 1e-14
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 32 1.0
AK094713-1|BAC04405.1| 945|Homo sapiens protein ( Homo sapiens ... 29 7.3
AJ131721-1|CAB38232.1| 613|Homo sapiens alpha integrin interact... 29 7.3
AF534402-1|AAO25964.1| 1015|Homo sapiens HPS5 protein minor form... 29 7.3
AF534401-1|AAO25963.1| 1129|Homo sapiens HPS5 protein major form... 29 7.3
AF534400-1|AAO25962.1| 1015|Homo sapiens HPS5 protein protein. 29 7.3
AB231764-1|BAE17137.1| 1963|Homo sapiens hypothetical protein pr... 29 7.3
AB082529-1|BAC02707.1| 607|Homo sapiens KIAA1998 protein protein. 29 7.3
AB023234-1|BAA76861.2| 1095|Homo sapiens KIAA1017 protein protein. 29 7.3
BC033640-1|AAH33640.1| 1015|Homo sapiens Hermansky-Pudlak syndro... 29 9.7
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 104 bits (250), Expect = 2e-22
Identities = 46/91 (50%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
F ++F++GVS++A QIEGAW+ DGK SIWD+ H VKD + D+A DSYH D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
M+ L V YRFS+SW RI PTG + IN
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSIN 993
Score = 98.7 bits (235), Expect = 1e-20
Identities = 48/92 (52%), Positives = 57/92 (61%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 419
+FPE FI+ ++AA QIEGAW DGK SIWD H P V++ + DVA DSYH
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 1434
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
D + LGV YRFS+SW RILP G T IN
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYIN 1466
Score = 73.7 bits (173), Expect = 3e-13
Identities = 36/86 (41%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDG-SNADVASDSYHLYKR 419
FPE F++G ST A +EG W G+ SIWD + P +G + +VASDSYH
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTG 497
D ++ L Y+FS+SW RI P G
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMG 464
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 104 bits (250), Expect = 2e-22
Identities = 46/91 (50%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
F ++F++GVS++A QIEGAW+ DGK SIWD+ H VKD + D+A DSYH D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
M+ L V YRFS+SW RI PTG + IN
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSIN 993
Score = 98.7 bits (235), Expect = 1e-20
Identities = 48/92 (52%), Positives = 57/92 (61%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 419
+FPE FI+ ++AA QIEGAW DGK SIWD H P V++ + DVA DSYH
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 1434
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
D + LGV YRFS+SW RILP G T IN
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYIN 1466
Score = 73.7 bits (173), Expect = 3e-13
Identities = 36/86 (41%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDG-SNADVASDSYHLYKR 419
FPE F++G ST A +EG W G+ SIWD + P +G + +VASDSYH
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTG 497
D ++ L Y+FS+SW RI P G
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMG 464
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 104 bits (250), Expect = 2e-22
Identities = 46/91 (50%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
F ++F++GVS++A QIEGAW+ DGK SIWD+ H VKD + D+A DSYH D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
M+ L V YRFS+SW RI PTG + IN
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSIN 425
Score = 98.7 bits (235), Expect = 1e-20
Identities = 48/92 (52%), Positives = 57/92 (61%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 419
+FPE FI+ ++AA QIEGAW DGK SIWD H P V++ + DVA DSYH
Sbjct: 808 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 866
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
D + LGV YRFS+SW RILP G T IN
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYIN 898
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 104 bits (250), Expect = 2e-22
Identities = 46/91 (50%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
F ++F++GVS++A QIEGAW+ DGK SIWD+ H VKD + D+A DSYH D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
M+ L V YRFS+SW RI PTG + IN
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSIN 993
Score = 98.7 bits (235), Expect = 1e-20
Identities = 48/92 (52%), Positives = 57/92 (61%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 419
+FPE FI+ ++AA QIEGAW DGK SIWD H P V++ + DVA DSYH
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 1434
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
D + LGV YRFS+SW RILP G T IN
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYIN 1466
Score = 73.7 bits (173), Expect = 3e-13
Identities = 36/86 (41%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDG-SNADVASDSYHLYKR 419
FPE F++G ST A +EG W G+ SIWD + P +G + +VASDSYH
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438
Query: 420 DAEMVHELGVDTYRFSVSWPRILPTG 497
D ++ L Y+FS+SW RI P G
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMG 464
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 94.3 bits (224), Expect = 2e-19
Identities = 39/91 (42%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP+NF +G+ T A Q+EG+W DGK SIWDH +H + +K+ S+ + +SDSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ +GV Y+FS+SWPR+ P G+ N
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVAN 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSES---IWD----HLVHKNPEFVKDGSNADVASD 398
+FP +F +GV+ + + E + S+ +W+ L+H+ E V+ + +D
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHR-VEGVRLKTRPAQCTD 578
Query: 399 SYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
++ K+ EM+ + V YRF++ W +LPTG + +N
Sbjct: 579 FVNI-KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVN 616
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 94.3 bits (224), Expect = 2e-19
Identities = 39/91 (42%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP+NF +G+ T A Q+EG+W DGK SIWDH +H + +K+ S+ + +SDSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ +GV Y+FS+SWPR+ P G+ N
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVAN 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSES---IWD----HLVHKNPEFVKDGSNADVASD 398
+FP +F +GV+ + + E + S+ +W+ L+H+ E V+ + +D
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHR-VEGVRLKTRPAQCTD 578
Query: 399 SYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
++ K+ EM+ + V YRF++ W +LPTG + +N
Sbjct: 579 FVNI-KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVN 616
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 94.3 bits (224), Expect = 2e-19
Identities = 39/91 (42%), Positives = 59/91 (64%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP+NF +G+ T A Q+EG+W DGK SIWDH +H + +K+ S+ + +SDSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ +GV Y+FS+SWPR+ P G+ N
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVAN 168
Score = 35.5 bits (78), Expect = 0.11
Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 7/99 (7%)
Frame = +3
Query: 240 KFPENFIFGVSTAAAQIEGAWNVDGKSES---IWD----HLVHKNPEFVKDGSNADVASD 398
+FP +F +GV+ + + E + S+ +W+ L+H+ E V+ + +D
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHR-VEGVRLKTRPAQCTD 578
Query: 399 SYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
++ K+ EM+ + V YRF++ W +LPTG + +N
Sbjct: 579 FVNI-KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVN 616
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 93.5 bits (222), Expect = 4e-19
Identities = 43/89 (48%), Positives = 55/89 (61%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F +GV ++A Q EGAW+ DGK SIWD H V ADVA D Y+ + D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNE 509
++ EL V+ YRFS+SWPR+LPTG+ E
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAE 125
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 91.1 bits (216), Expect = 2e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 90.2 bits (214), Expect = 4e-18
Identities = 40/91 (43%), Positives = 54/91 (59%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 422
FP F + +TAA Q+EG W+ DGK +WD H+ E V DVA SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 423 AEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ + +LG+ YRFS+SW R+LP G T IN
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFIN 93
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 78.6 bits (185), Expect = 1e-14
Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 383
FP+ F++ V +AA Q EG W GK SIWD H D NA
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 384 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTG 497
DVASDSY+ RD E + ELGV YRFS+SW R+LP G
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNG 160
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 78.6 bits (185), Expect = 1e-14
Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 383
FP+ F++ V +AA Q EG W GK SIWD H D NA
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 384 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTG 497
DVASDSY+ RD E + ELGV YRFS+SW R+LP G
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNG 160
Score = 32.3 bits (70), Expect = 1.0
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 410
FP +F +GV Q++ + + +WD VH + +K SY +
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 411 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ ++ E+ V +RFS+ W ILP G +++N
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVN 612
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 78.6 bits (185), Expect = 1e-14
Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 383
FP+ F++ V +AA Q EG W GK SIWD H D NA
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 384 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTG 497
DVASDSY+ RD E + ELGV YRFS+SW R+LP G
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNG 160
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 78.6 bits (185), Expect = 1e-14
Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 383
FP+ F++ V +AA Q EG W GK SIWD H D NA
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 384 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTG 497
DVASDSY+ RD E + ELGV YRFS+SW R+LP G
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNG 160
Score = 32.3 bits (70), Expect = 1.0
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 410
FP +F +GV Q++ + + +WD VH + +K SY +
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 411 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ ++ E+ V +RFS+ W ILP G +++N
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVN 612
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 78.6 bits (185), Expect = 1e-14
Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 383
FP+ F++ V +AA Q EG W GK SIWD H D NA
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 384 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTG 497
DVASDSY+ RD E + ELGV YRFS+SW R+LP G
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNG 160
Score = 32.3 bits (70), Expect = 1.0
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 410
FP +F +GV Q++ + + +WD VH + +K SY +
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 411 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ ++ E+ V +RFS+ W ILP G +++N
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVN 612
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 32.3 bits (70), Expect = 1.0
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 5/96 (5%)
Frame = +3
Query: 243 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 410
FP +F +GV Q++ + + +WD VH + +K SY +
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 303
Query: 411 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEIN 515
+ ++ E+ V +RFS+ W ILP G +++N
Sbjct: 304 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVN 339
>AK094713-1|BAC04405.1| 945|Homo sapiens protein ( Homo sapiens
cDNA FLJ37394 fis, clone BRAMY2027140, highly similar to
RHO-GUANINE NUCLEOTIDE EXCHANGE FACTOR. ).
Length = 945
Score = 29.5 bits (63), Expect = 7.3
Identities = 16/48 (33%), Positives = 25/48 (52%)
Frame = -3
Query: 224 SSS*IDNLSVSFTQKGYD*NQSHFKINKEVYFTLDVNTKVKSMNVKSH 81
SSS NL++SF G++ QSH K LD +++ + + SH
Sbjct: 449 SSSCASNLNLSFGWHGFEKEQSHLKKRSSSLDALDADSEGEGHSEPSH 496
>AJ131721-1|CAB38232.1| 613|Homo sapiens alpha integrin interacting
protein 63 protein.
Length = 613
Score = 29.5 bits (63), Expect = 7.3
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = -2
Query: 483 FWATIQKICMYQLRAREPFQHRAYINDKNLMQRPR-WI 373
FW +C+ R RE F + Y+ND +LM+ WI
Sbjct: 469 FWPGYLILCLELERRREAFTNIVYLNDMSLMEGDNGWI 506
>AF534402-1|AAO25964.1| 1015|Homo sapiens HPS5 protein minor form
protein.
Length = 1015
Score = 29.5 bits (63), Expect = 7.3
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = -2
Query: 483 FWATIQKICMYQLRAREPFQHRAYINDKNLMQRPR-WI 373
FW +C+ R RE F + Y+ND +LM+ WI
Sbjct: 871 FWPGYLILCLELERRREAFTNIVYLNDMSLMEGDNGWI 908
>AF534401-1|AAO25963.1| 1129|Homo sapiens HPS5 protein major form
protein.
Length = 1129
Score = 29.5 bits (63), Expect = 7.3
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = -2
Query: 483 FWATIQKICMYQLRAREPFQHRAYINDKNLMQRPR-WI 373
FW +C+ R RE F + Y+ND +LM+ WI
Sbjct: 985 FWPGYLILCLELERRREAFTNIVYLNDMSLMEGDNGWI 1022
>AF534400-1|AAO25962.1| 1015|Homo sapiens HPS5 protein protein.
Length = 1015
Score = 29.5 bits (63), Expect = 7.3
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = -2
Query: 483 FWATIQKICMYQLRAREPFQHRAYINDKNLMQRPR-WI 373
FW +C+ R RE F + Y+ND +LM+ WI
Sbjct: 871 FWPGYLILCLELERRREAFTNIVYLNDMSLMEGDNGWI 908
>AB231764-1|BAE17137.1| 1963|Homo sapiens hypothetical protein
protein.
Length = 1963
Score = 29.5 bits (63), Expect = 7.3
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 2/57 (3%)
Frame = +3
Query: 201 EIVNLAGGKNTN--YKFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFV 365
E+V LA K T+ KF + F+F V IE WN + + K PE +
Sbjct: 602 EVVRLASSKITDGKVKFQQRFVFPVQFGGPMIEHWWNSNLTFQIYVKKTPQKKPEVI 658
>AB082529-1|BAC02707.1| 607|Homo sapiens KIAA1998 protein protein.
Length = 607
Score = 29.5 bits (63), Expect = 7.3
Identities = 16/48 (33%), Positives = 25/48 (52%)
Frame = -3
Query: 224 SSS*IDNLSVSFTQKGYD*NQSHFKINKEVYFTLDVNTKVKSMNVKSH 81
SSS NL++SF G++ QSH K LD +++ + + SH
Sbjct: 454 SSSCASNLNLSFGWHGFEKEQSHLKKRSSSLDALDADSEGEGHSEPSH 501
>AB023234-1|BAA76861.2| 1095|Homo sapiens KIAA1017 protein protein.
Length = 1095
Score = 29.5 bits (63), Expect = 7.3
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = -2
Query: 483 FWATIQKICMYQLRAREPFQHRAYINDKNLMQRPR-WI 373
FW +C+ R RE F + Y+ND +LM+ WI
Sbjct: 951 FWPGYLILCLELERRREAFTNIVYLNDMSLMEGDNGWI 988
>BC033640-1|AAH33640.1| 1015|Homo sapiens Hermansky-Pudlak syndrome
5 protein.
Length = 1015
Score = 29.1 bits (62), Expect = 9.7
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Frame = -2
Query: 483 FWATIQKICMYQLRAREPFQHRAYINDKNLMQRPR-WI 373
FW +C+ R RE F + Y+ND +LM+ WI
Sbjct: 871 FWPGYLILCLELERRREAFTNIVYLNDMSLMKGDNGWI 908
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,688,864
Number of Sequences: 237096
Number of extensions: 1424649
Number of successful extensions: 9627
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 5895
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9617
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4876707572
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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