Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt16k18
(628 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein. 67 4e-11
BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette, s... 67 4e-11
AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette, s... 67 4e-11
AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein. 67 4e-11
AC002457-1|AAM49149.1| 234|Homo sapiens unknown protein. 67 4e-11
M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein. 64 5e-10
M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane ... 62 2e-09
EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette, s... 62 2e-09
BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette, s... 62 2e-09
AC006154-1|AAD05023.1| 407|Homo sapiens unknown protein. 61 3e-09
AB353947-1|BAF75364.1| 1257|Homo sapiens ATP-binding cassette, s... 58 2e-08
BC020618-1|AAH20618.1| 179|Homo sapiens ABCB4 protein protein. 49 2e-05
AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump p... 48 2e-05
AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump p... 48 2e-05
AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein. 48 2e-05
DQ861346-1|ABH04421.1| 63|Homo sapiens variant ATP-binding cas... 34 0.36
AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance pr... 34 0.36
BC151235-1|AAI51236.1| 718|Homo sapiens ATP-binding cassette, s... 32 1.9
BC141836-1|AAI41837.1| 693|Homo sapiens ABCB8 protein protein. 32 1.9
BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette, s... 32 1.9
BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette, s... 32 1.9
AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette, s... 32 1.9
AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette, s... 32 1.9
AK128129-1|BAC87287.1| 467|Homo sapiens . protein. 32 1.9
AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens ... 32 1.9
AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens ... 32 1.9
AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein. 32 1.9
AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding casset... 32 1.9
AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette pr... 30 7.7
>M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.
Length = 1280
Score = 67.3 bits (157), Expect = 4e-11
Identities = 41/170 (24%), Positives = 83/170 (48%)
Frame = +3
Query: 108 SLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSK 287
++S F +FRY+ WL+ ++GT+ ++ G+ ++ GEM+ F D +++
Sbjct: 33 TVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNI 92
Query: 288 MPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALK 467
+ G + EE+M + G V+ + V+ +A +
Sbjct: 93 TNRSDINDTG---FFMNLEEDMTRYAYYYSGIGAGVLVAAY-------IQVSFWCLAAGR 142
Query: 468 QITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
QI IRK F A++RQ++ WFD L +++++++ K+ EG+G+K+ +
Sbjct: 143 QIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 34.3 bits (75), Expect = 0.36
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFDTDSDFN--LASKMSENLMKLKEGMGEKLAVVS 623
+R + ++LRQD++WFD + L ++++ + ++K +G +LAV++
Sbjct: 788 LRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 67.3 bits (157), Expect = 4e-11
Identities = 41/170 (24%), Positives = 83/170 (48%)
Frame = +3
Query: 108 SLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSK 287
++S F +FRY+ WL+ ++GT+ ++ G+ ++ GEM+ F D +++
Sbjct: 33 TVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNI 92
Query: 288 MPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALK 467
+ G + EE+M + G V+ + V+ +A +
Sbjct: 93 TNRSDINDTG---FFMNLEEDMTRYAYYYSGIGAGVLVAAY-------IQVSFWCLAAGR 142
Query: 468 QITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
QI IRK F A++RQ++ WFD L +++++++ K+ EG+G+K+ +
Sbjct: 143 QIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 34.3 bits (75), Expect = 0.36
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFDTDSDFN--LASKMSENLMKLKEGMGEKLAVVS 623
+R + ++LRQD++WFD + L ++++ + ++K +G +LAV++
Sbjct: 788 LRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 67.3 bits (157), Expect = 4e-11
Identities = 41/170 (24%), Positives = 83/170 (48%)
Frame = +3
Query: 108 SLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSK 287
++S F +FRY+ WL+ ++GT+ ++ G+ ++ GEM+ F D +++
Sbjct: 33 TVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNI 92
Query: 288 MPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALK 467
+ G + EE+M + G V+ + V+ +A +
Sbjct: 93 TNRSDINDTG---FFMNLEEDMTRYAYYYSGIGAGVLVAAY-------IQVSFWCLAAGR 142
Query: 468 QITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
QI IRK F A++RQ++ WFD L +++++++ K+ EG+G+K+ +
Sbjct: 143 QIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 34.3 bits (75), Expect = 0.36
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFDTDSDFN--LASKMSENLMKLKEGMGEKLAVVS 623
+R + ++LRQD++WFD + L ++++ + ++K +G +LAV++
Sbjct: 788 LRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.
Length = 1279
Score = 67.3 bits (157), Expect = 4e-11
Identities = 41/170 (24%), Positives = 83/170 (48%)
Frame = +3
Query: 108 SLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSK 287
++S F +FRY+ WL+ ++GT+ ++ G+ ++ GEM+ F D +++
Sbjct: 33 TVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNI 92
Query: 288 MPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALK 467
+ G + EE+M + G V+ + V+ +A +
Sbjct: 93 TNRSDINDTG---FFMNLEEDMTRYAYYYSGIGAGVLVAAY-------IQVSFWCLAAGR 142
Query: 468 QITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
QI IRK F A++RQ++ WFD L +++++++ K+ EG+G+K+ +
Sbjct: 143 QIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 34.3 bits (75), Expect = 0.36
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFDTDSDFN--LASKMSENLMKLKEGMGEKLAVVS 623
+R + ++LRQD++WFD + L ++++ + ++K +G +LAV++
Sbjct: 787 LRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 836
>AC002457-1|AAM49149.1| 234|Homo sapiens unknown protein.
Length = 234
Score = 67.3 bits (157), Expect = 4e-11
Identities = 41/170 (24%), Positives = 83/170 (48%)
Frame = +3
Query: 108 SLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSK 287
++S F +FRY+ WL+ ++GT+ ++ G+ ++ GEM+ F D +++
Sbjct: 33 TVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNI 92
Query: 288 MPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALK 467
+ G + EE+M + G V+ + V+ +A +
Sbjct: 93 TNRSDINDTG---FFMNLEEDMTRYAYYYSGIGAGVLVAAY-------IQVSFWCLAAGR 142
Query: 468 QITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
QI IRK F A++RQ++ WFD L +++++++ K+ EG+G+K+ +
Sbjct: 143 QIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
>M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.
Length = 1280
Score = 63.7 bits (148), Expect = 5e-10
Identities = 40/170 (23%), Positives = 82/170 (48%)
Frame = +3
Query: 108 SLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSK 287
++S F +FRY+ WL+ ++GT+ ++ G+ ++ GEM+ F D +++
Sbjct: 33 TVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNI 92
Query: 288 MPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALK 467
+ G + EE+M + G V+ + V+ +A +
Sbjct: 93 TNRSDINDTG---FFMNLEEDMTRYAYYYSGIGAGVLVAAY-------IQVSFWCLAAGR 142
Query: 468 QITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
QI IRK F A++RQ++ WFD L +++++++ K+ E +G+K+ +
Sbjct: 143 QIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEVIGDKIGM 192
Score = 34.3 bits (75), Expect = 0.36
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFDTDSDFN--LASKMSENLMKLKEGMGEKLAVVS 623
+R + ++LRQD++WFD + L ++++ + ++K +G +LAV++
Sbjct: 788 LRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane
glycoprotein P (mdr3) mRNA, complete cds. ).
Length = 1279
Score = 62.1 bits (144), Expect = 2e-09
Identities = 43/164 (26%), Positives = 79/164 (48%)
Frame = +3
Query: 126 IFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSKMPIMSL 305
+FRY+ W + LGT+ + G+ ++ GEM+ FV+ T + SL
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVD-TAGNFSFPVNFSL-SL 102
Query: 306 FGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALKQITTIR 485
G+ L EE M + G V+ + V+ + +A +QI IR
Sbjct: 103 LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAY-------IQVSFWTLAAGRQIRKIR 150
Query: 486 KLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
+ F A+LRQ++ WFD + L +++++++ K+ EG+G+K+ +
Sbjct: 151 QKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 194
Score = 33.9 bits (74), Expect = 0.47
Identities = 15/50 (30%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFD--TDSDFNLASKMSENLMKLKEGMGEKLAVVS 623
+R + A+LRQDM+WFD +S L+++++ + +++ G +LA+++
Sbjct: 787 LRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIA 836
>EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 62.1 bits (144), Expect = 2e-09
Identities = 43/164 (26%), Positives = 79/164 (48%)
Frame = +3
Query: 126 IFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSKMPIMSL 305
+FRY+ W + LGT+ + G+ ++ GEM+ FV+ T + SL
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVD-TAGNFSFPVNFSL-SL 102
Query: 306 FGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALKQITTIR 485
G+ L EE M + G V+ + V+ + +A +QI IR
Sbjct: 103 LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAY-------IQVSFWTLAAGRQIRKIR 150
Query: 486 KLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
+ F A+LRQ++ WFD + L +++++++ K+ EG+G+K+ +
Sbjct: 151 QKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 194
Score = 33.9 bits (74), Expect = 0.47
Identities = 15/50 (30%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFD--TDSDFNLASKMSENLMKLKEGMGEKLAVVS 623
+R + A+LRQDM+WFD +S L+++++ + +++ G +LA+++
Sbjct: 787 LRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIA 836
>BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 62.1 bits (144), Expect = 2e-09
Identities = 43/164 (26%), Positives = 79/164 (48%)
Frame = +3
Query: 126 IFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSKMPIMSL 305
+FRY+ W + LGT+ + G+ ++ GEM+ FV+ T + SL
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVD-TAGNFSFPVNFSL-SL 102
Query: 306 FGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALKQITTIR 485
G+ L EE M + G V+ + V+ + +A +QI IR
Sbjct: 103 LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAY-------IQVSFWTLAAGRQIRKIR 150
Query: 486 KLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
+ F A+LRQ++ WFD + L +++++++ K+ EG+G+K+ +
Sbjct: 151 QKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 194
Score = 33.9 bits (74), Expect = 0.47
Identities = 15/50 (30%), Positives = 33/50 (66%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFD--TDSDFNLASKMSENLMKLKEGMGEKLAVVS 623
+R + A+LRQDM+WFD +S L+++++ + +++ G +LA+++
Sbjct: 787 LRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIA 836
>AC006154-1|AAD05023.1| 407|Homo sapiens unknown protein.
Length = 407
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/163 (26%), Positives = 78/163 (47%)
Frame = +3
Query: 129 FRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSKMPIMSLF 308
FRY+ W + LGT+ + G+ ++ GEM+ FV+ T + SL
Sbjct: 1 FRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVD-TAGNFSFPVNFSL-SLL 58
Query: 309 GGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALKQITTIRK 488
G+ L EE M + G V+ + V+ + +A +QI IR+
Sbjct: 59 NPGKIL-----EEEMTRYAYYYSGLGAGVLVAAY-------IQVSFWTLAAGRQIRKIRQ 106
Query: 489 LFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
F A+LRQ++ WFD + L +++++++ K+ EG+G+K+ +
Sbjct: 107 KFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 149
>AB353947-1|BAF75364.1| 1257|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 1257
Score = 58.4 bits (135), Expect = 2e-08
Identities = 43/174 (24%), Positives = 88/174 (50%), Gaps = 1/174 (0%)
Frame = +3
Query: 102 ESSLSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLT 281
+ ++ +IFR+A L++T ILG + L++ + + +GEMS + + T
Sbjct: 28 KEAVGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISGCLVQTNTT 87
Query: 282 SKMPIMSLFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSI-IFSILCNVLSVALVSWS 458
+ N T + L ED + + +V I + +++ + ++L +
Sbjct: 88 NYQ-------------NCTQSQEK--LNEDMTLLTL-YYVGIGVAALIFGYIQISLWIIT 131
Query: 459 ALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAVV 620
A +Q IRK F +VL QD+ WFD+ L ++M++++ K+ +G+G+K+A++
Sbjct: 132 AARQTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALL 185
>BC020618-1|AAH20618.1| 179|Homo sapiens ABCB4 protein protein.
Length = 179
Score = 48.8 bits (111), Expect = 2e-05
Identities = 39/149 (26%), Positives = 67/149 (44%)
Frame = +3
Query: 126 IFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRLTSKMPIMSL 305
+FRY+ W + LGT+ + G+ ++ GEM+ FV+ T + SL
Sbjct: 45 LFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVD-TAGNFSFPVNFSL-SL 102
Query: 306 FGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSWSALKQITTIR 485
G+ L EE M + G V+ + V+ + +A +QI IR
Sbjct: 103 LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAY-------IQVSFWTLAAGRQIRKIR 150
Query: 486 KLFLTAVLRQDMTWFDTDSDFNLASKMSE 572
+ F A+LRQ++ WFD + L ++++E
Sbjct: 151 QKFFHAILRQEIGWFDINDTTELNTRLTE 179
>AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/175 (18%), Positives = 83/175 (47%), Gaps = 6/175 (3%)
Frame = +3
Query: 111 LSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRL--TS 284
+ FFQ+FR+++ ++ +G++ L L+ G M+ F++ V L
Sbjct: 45 VGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQIPG 104
Query: 285 KMPIMS--LFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSW- 455
K + + ++ N T+ L +++ + ++ + I + + + W
Sbjct: 105 KACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICFWV 164
Query: 456 -SALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
+A +QI +RK + ++R ++ WFD +S L ++ S+++ K+ + + +++A+
Sbjct: 165 IAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMAL 219
>AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/175 (18%), Positives = 83/175 (47%), Gaps = 6/175 (3%)
Frame = +3
Query: 111 LSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRL--TS 284
+ FFQ+FR+++ ++ +G++ L L+ G M+ F++ V L
Sbjct: 45 VGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQIPG 104
Query: 285 KMPIMS--LFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSW- 455
K + + ++ N T+ L +++ + ++ + I + + + W
Sbjct: 105 KACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICFWV 164
Query: 456 -SALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
+A +QI +RK + ++R ++ WFD +S L ++ S+++ K+ + + +++A+
Sbjct: 165 IAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMAL 219
>AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein.
Length = 870
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/175 (18%), Positives = 83/175 (47%), Gaps = 6/175 (3%)
Frame = +3
Query: 111 LSFFQIFRYATWLELTATILGTVFGLLSAGGVTYNLMQVGEMSTAFVERTVPPDRL--TS 284
+ FFQ+FR+++ ++ +G++ L L+ G M+ F++ V L
Sbjct: 45 VGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQIPG 104
Query: 285 KMPIMS--LFGGGRRLYNATHEENMAALIEDAQAVAIGAFVSIIFSILCNVLSVALVSW- 455
K + + ++ N T+ L +++ + ++ + I + + + W
Sbjct: 105 KACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICFWV 164
Query: 456 -SALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLKEGMGEKLAV 617
+A +QI +RK + ++R ++ WFD +S L ++ S+++ K+ + + +++A+
Sbjct: 165 IAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMAL 219
>DQ861346-1|ABH04421.1| 63|Homo sapiens variant ATP-binding
cassette sub-family B member 4 protein.
Length = 63
Score = 34.3 bits (75), Expect = 0.36
Identities = 15/46 (32%), Positives = 29/46 (63%)
Frame = +3
Query: 432 LSVALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMS 569
+ V+ + +A +QI IR+ F A+LRQ++ WFD + L ++++
Sbjct: 18 IQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLT 63
>AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance
protein 1 variant protein.
Length = 1062
Score = 34.3 bits (75), Expect = 0.36
Identities = 14/50 (28%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Frame = +3
Query: 480 IRKLFLTAVLRQDMTWFDTDSDFN--LASKMSENLMKLKEGMGEKLAVVS 623
+R + ++LRQD++WFD + L ++++ + ++K +G +LAV++
Sbjct: 570 LRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 619
>BC151235-1|AAI51236.1| 718|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 8 protein.
Length = 718
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 196 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 246
>BC141836-1|AAI41837.1| 693|Homo sapiens ABCB8 protein protein.
Length = 693
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 196 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 246
>BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 8 protein.
Length = 718
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 196 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 246
>BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 31.9 bits (69), Expect = 1.9
Identities = 16/78 (20%), Positives = 36/78 (46%)
Frame = +3
Query: 381 VAIGAFVSIIFSILCNVLSVALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLAS 560
+ +G + N + V L+ S + + +R +++LRQ++ +FD L +
Sbjct: 214 LCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELIN 273
Query: 561 KMSENLMKLKEGMGEKLA 614
++S + L + E L+
Sbjct: 274 RLSSDTALLGRSVTENLS 291
>AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 31.9 bits (69), Expect = 1.9
Identities = 16/78 (20%), Positives = 36/78 (46%)
Frame = +3
Query: 381 VAIGAFVSIIFSILCNVLSVALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLAS 560
+ +G + N + V L+ S + + +R +++LRQ++ +FD L +
Sbjct: 214 LCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELIN 273
Query: 561 KMSENLMKLKEGMGEKLA 614
++S + L + E L+
Sbjct: 274 RLSSDTALLGRSVTENLS 291
>AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette,
sub-family B, member 8 variant protein.
Length = 718
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 196 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 246
>AK128129-1|BAC87287.1| 467|Homo sapiens . protein.
Length = 467
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 233 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 283
>AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens
cDNA FLJ37317 fis, clone BRAMY2017455, highly similar to
Homo sapiens ATP-binding cassette protein M-ABC1 mRNA.
).
Length = 701
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 179 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 229
>AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens
cDNA FLJ11156 fis, clone PLACE1006956, weakly similar to
ATP-DEPENDENT PERMEASE MDL1. ).
Length = 735
Score = 31.9 bits (69), Expect = 1.9
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQD+T+FD + L S+++ ++ + K
Sbjct: 213 LVLLSHVGERMAVDMRRALFSSLLRQDITFFDANKTGQLVSRLTTDVQEFK 263
>AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein.
Length = 738
Score = 31.9 bits (69), Expect = 1.9
Identities = 16/78 (20%), Positives = 36/78 (46%)
Frame = +3
Query: 381 VAIGAFVSIIFSILCNVLSVALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLAS 560
+ +G + N + V L+ S + + +R +++LRQ++ +FD L +
Sbjct: 214 LCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELIN 273
Query: 561 KMSENLMKLKEGMGEKLA 614
++S + L + E L+
Sbjct: 274 RLSSDTALLGRSVTENLS 291
>AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding cassette
protein protein.
Length = 737
Score = 31.9 bits (69), Expect = 1.9
Identities = 16/78 (20%), Positives = 36/78 (46%)
Frame = +3
Query: 381 VAIGAFVSIIFSILCNVLSVALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLAS 560
+ +G + N + V L+ S + + +R +++LRQ++ +FD L +
Sbjct: 214 LCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELIN 273
Query: 561 KMSENLMKLKEGMGEKLA 614
++S + L + E L+
Sbjct: 274 RLSSDTALLGRSVTENLS 291
>AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette
protein M-ABC1 protein.
Length = 718
Score = 29.9 bits (64), Expect = 7.7
Identities = 12/51 (23%), Positives = 30/51 (58%)
Frame = +3
Query: 438 VALVSWSALKQITTIRKLFLTAVLRQDMTWFDTDSDFNLASKMSENLMKLK 590
+ L+S + +R+ +++LRQ++T+FD + L S+++ ++ + K
Sbjct: 196 LVLLSHVGERMAVDMRRALFSSLLRQNITFFDANKTGQLVSRLTTDVQEFK 246
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,024,169
Number of Sequences: 237096
Number of extensions: 1926381
Number of successful extensions: 4654
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 4478
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4648
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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