Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt13h18
(636 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 307 3e-83
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 307 3e-83
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 307 3e-83
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 307 3e-83
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 307 3e-83
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 307 3e-83
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 306 5e-83
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 305 6e-83
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 305 1e-82
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 287 3e-77
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 286 4e-77
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 286 4e-77
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 286 4e-77
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 267 3e-71
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 239 4e-63
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 142 1e-33
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 6.0
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 6.0
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 141/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 141/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 141/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 141/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 141/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 141/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 306 bits (751), Expect = 5e-83
Identities = 140/194 (72%), Positives = 168/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 305 bits (750), Expect = 6e-83
Identities = 140/194 (72%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 305 bits (748), Expect = 1e-82
Identities = 141/194 (72%), Positives = 166/194 (85%), Gaps = 2/194 (1%)
Frame = +3
Query: 60 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 239
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 240 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 419
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 420 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMF 593
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 594 NTDASIIDFAHSSF 635
N D SI DFAHSSF
Sbjct: 184 NQDKSIEDFAHSSF 197
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 287 bits (703), Expect = 3e-77
Identities = 136/203 (66%), Positives = 157/203 (77%), Gaps = 2/203 (0%)
Frame = +3
Query: 33 YSRHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTD 209
+ R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TD
Sbjct: 34 HPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTD 93
Query: 210 DQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAII 389
DQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE II
Sbjct: 94 DQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII 153
Query: 390 CKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYK 566
CKNIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 154 CKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP 213
Query: 567 GAGVALAMFNTDASIIDFAHSSF 635
GV + M+NTD SI FAHS F
Sbjct: 214 AGGVGMGMYNTDESISGFAHSCF 236
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 286 bits (702), Expect = 4e-77
Identities = 136/201 (67%), Positives = 156/201 (77%), Gaps = 2/201 (0%)
Frame = +3
Query: 39 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 215
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 216 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 395
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 396 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 572
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 573 GVALAMFNTDASIIDFAHSSF 635
GV + M+NTD SI FAHS F
Sbjct: 216 GVGMGMYNTDESISGFAHSCF 236
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 286 bits (702), Expect = 4e-77
Identities = 136/201 (67%), Positives = 156/201 (77%), Gaps = 2/201 (0%)
Frame = +3
Query: 39 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 215
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 216 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 395
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 396 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 572
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 573 GVALAMFNTDASIIDFAHSSF 635
GV + M+NTD SI FAHS F
Sbjct: 216 GVGMGMYNTDESISGFAHSCF 236
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 286 bits (702), Expect = 4e-77
Identities = 136/201 (67%), Positives = 156/201 (77%), Gaps = 2/201 (0%)
Frame = +3
Query: 39 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 215
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 216 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 395
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 396 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 572
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 573 GVALAMFNTDASIIDFAHSSF 635
GV + M+NTD SI FAHS F
Sbjct: 216 GVGMGMYNTDESISGFAHSCF 236
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 267 bits (654), Expect = 3e-71
Identities = 122/168 (72%), Positives = 145/168 (86%), Gaps = 2/168 (1%)
Frame = +3
Query: 138 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 317
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 318 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 497
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 498 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSF 635
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSF 168
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 239 bits (586), Expect = 4e-63
Identities = 110/162 (67%), Positives = 127/162 (78%), Gaps = 1/162 (0%)
Frame = +3
Query: 153 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 332
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 333 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 512
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 513 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSF 635
+F P+ G +K V+ + GV + M+NTD SI FAHS F
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCF 203
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 142 bits (343), Expect = 1e-33
Identities = 66/98 (67%), Positives = 79/98 (80%), Gaps = 2/98 (2%)
Frame = +3
Query: 348 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 527
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 528 SG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSF 635
G + + ++VH + +G GVA+ M+N D SI DFAHSSF
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSF 98
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 6.0
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 410 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 580
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 581 TGYV*H*C 604
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 6.0
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 410 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 580
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 581 TGYV*H*C 604
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,102,353
Number of Sequences: 237096
Number of extensions: 2137983
Number of successful extensions: 3902
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3737
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3880
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6972732040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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