Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt11g03
(626 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L10413-1|AAA86285.1| 379|Homo sapiens farnesyl-protein transfer... 281 1e-75
L00634-1|AAA35853.1| 379|Homo sapiens farnesyl-protein transfer... 281 1e-75
BT009854-1|AAP88856.1| 379|Homo sapiens farnesyltransferase, CA... 281 1e-75
BC084566-1|AAH84566.1| 379|Homo sapiens farnesyltransferase, CA... 281 1e-75
BC017029-1|AAH17029.2| 376|Homo sapiens FNTA protein protein. 281 1e-75
BC037295-1|AAH37295.1| 214|Homo sapiens FNTA protein protein. 232 9e-61
Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl transf... 90 7e-18
CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein. 90 7e-18
BC003093-1|AAH03093.1| 567|Homo sapiens Rab geranylgeranyltrans... 90 7e-18
BC053622-1|AAH53622.1| 403|Homo sapiens PTAR1 protein protein. 44 4e-04
AL162412-2|CAI10945.2| 312|Homo sapiens protein prenyltransfera... 44 4e-04
AL162412-1|CAI10944.1| 350|Homo sapiens protein prenyltransfera... 40 0.010
>L10413-1|AAA86285.1| 379|Homo sapiens farnesyl-protein transferase
alpha-subunit protein.
Length = 379
Score = 281 bits (690), Expect = 1e-75
Identities = 118/184 (64%), Positives = 148/184 (80%)
Frame = +2
Query: 68 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 247
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 248 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRVLVEWLQDP 427
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQVWHHRRVLVEWL+DP
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP 182
Query: 428 TMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYEKELDFVDNLITDDVRNNSAWNQRYF 607
+ ELE D L QD KNYHAWQHRQW I+ F L++ EL +VD L+ +DVRNNS WNQRYF
Sbjct: 183 SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYF 242
Query: 608 VVNN 619
V++N
Sbjct: 243 VISN 246
>L00634-1|AAA35853.1| 379|Homo sapiens farnesyl-protein transferase
alpha-subunit protein.
Length = 379
Score = 281 bits (690), Expect = 1e-75
Identities = 118/184 (64%), Positives = 148/184 (80%)
Frame = +2
Query: 68 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 247
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 248 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRVLVEWLQDP 427
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQVWHHRRVLVEWL+DP
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP 182
Query: 428 TMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYEKELDFVDNLITDDVRNNSAWNQRYF 607
+ ELE D L QD KNYHAWQHRQW I+ F L++ EL +VD L+ +DVRNNS WNQRYF
Sbjct: 183 SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYF 242
Query: 608 VVNN 619
V++N
Sbjct: 243 VISN 246
>BT009854-1|AAP88856.1| 379|Homo sapiens farnesyltransferase, CAAX
box, alpha protein.
Length = 379
Score = 281 bits (690), Expect = 1e-75
Identities = 118/184 (64%), Positives = 148/184 (80%)
Frame = +2
Query: 68 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 247
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 248 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRVLVEWLQDP 427
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQVWHHRRVLVEWL+DP
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP 182
Query: 428 TMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYEKELDFVDNLITDDVRNNSAWNQRYF 607
+ ELE D L QD KNYHAWQHRQW I+ F L++ EL +VD L+ +DVRNNS WNQRYF
Sbjct: 183 SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYF 242
Query: 608 VVNN 619
V++N
Sbjct: 243 VISN 246
>BC084566-1|AAH84566.1| 379|Homo sapiens farnesyltransferase, CAAX
box, alpha protein.
Length = 379
Score = 281 bits (690), Expect = 1e-75
Identities = 118/184 (64%), Positives = 148/184 (80%)
Frame = +2
Query: 68 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 247
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 248 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRVLVEWLQDP 427
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQVWHHRRVLVEWL+DP
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP 182
Query: 428 TMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYEKELDFVDNLITDDVRNNSAWNQRYF 607
+ ELE D L QD KNYHAWQHRQW I+ F L++ EL +VD L+ +DVRNNS WNQRYF
Sbjct: 183 SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYF 242
Query: 608 VVNN 619
V++N
Sbjct: 243 VISN 246
>BC017029-1|AAH17029.2| 376|Homo sapiens FNTA protein protein.
Length = 376
Score = 281 bits (690), Expect = 1e-75
Identities = 118/184 (64%), Positives = 148/184 (80%)
Frame = +2
Query: 68 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 247
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 60 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 119
Query: 248 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRVLVEWLQDP 427
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQVWHHRRVLVEWL+DP
Sbjct: 120 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRDP 179
Query: 428 TMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYEKELDFVDNLITDDVRNNSAWNQRYF 607
+ ELE D L QD KNYHAWQHRQW I+ F L++ EL +VD L+ +DVRNNS WNQRYF
Sbjct: 180 SQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYF 239
Query: 608 VVNN 619
V++N
Sbjct: 240 VISN 243
>BC037295-1|AAH37295.1| 214|Homo sapiens FNTA protein protein.
Length = 214
Score = 232 bits (567), Expect = 9e-61
Identities = 99/149 (66%), Positives = 119/149 (79%)
Frame = +2
Query: 173 DVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEA 352
DVYDYFRAVLQ +E+SER LT+DA+ELN ANYTVW +RR LLK L DL E++Y+ A
Sbjct: 7 DVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITA 66
Query: 353 VIKNSPKNYQVWHHRRVLVEWLQDPTMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYE 532
+I+ PKNYQVWHHRRVLVEWL+DP+ ELE D L QD KNYHAWQHRQW I+ F L++
Sbjct: 67 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWD 126
Query: 533 KELDFVDNLITDDVRNNSAWNQRYFVVNN 619
EL +VD L+ +DVRNNS WNQRYFV++N
Sbjct: 127 NELQYVDQLLKEDVRNNSVWNQRYFVISN 155
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/88 (23%), Positives = 41/88 (46%)
Frame = +2
Query: 146 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 325
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 67 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 125
Query: 326 RTELDYVEAVIKNSPKNYQVWHHRRVLV 409
EL YV+ ++K +N VW+ R ++
Sbjct: 126 DNELQYVDQLLKEDVRNNSVWNQRYFVI 153
>Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl
transferase protein.
Length = 567
Score = 89.8 bits (213), Expect = 7e-18
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 12/145 (8%)
Frame = +2
Query: 203 QSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTD---------LRTELDYVEAV 355
Q+ E E VL LT L NP T+W RR++L+ L T ++ EL ++E+
Sbjct: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Query: 356 IKNSPKNYQVWHHRRVLVEWLQDP--TMELELTGDALLQDPKNYHAWQHRQW-AIKTFGL 526
++ +PK+Y WHHR L+ L +P T ELEL L D +N+H W +R++ A +
Sbjct: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159
Query: 527 YEKELDFVDNLITDDVRNNSAWNQR 601
+EL F D+LIT + N S+W+ R
Sbjct: 160 PAEELAFTDSLITRNFSNYSSWHYR 184
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 14/110 (12%)
Frame = +2
Query: 224 RVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRV 403
R L L LE++ N+ W YRR + EL + +++I + NY WH+R
Sbjct: 127 RELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSSWHYRSC 186
Query: 404 LVEWL-------------QDPTM-ELELTGDALLQDPKNYHAWQHRQWAI 511
L+ L +D + ELEL +A DP + AW + +W +
Sbjct: 187 LLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLL 236
>CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein.
Length = 567
Score = 89.8 bits (213), Expect = 7e-18
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 12/145 (8%)
Frame = +2
Query: 203 QSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTD---------LRTELDYVEAV 355
Q+ E E VL LT L NP T+W RR++L+ L T ++ EL ++E+
Sbjct: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Query: 356 IKNSPKNYQVWHHRRVLVEWLQDP--TMELELTGDALLQDPKNYHAWQHRQW-AIKTFGL 526
++ +PK+Y WHHR L+ L +P T ELEL L D +N+H W +R++ A +
Sbjct: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159
Query: 527 YEKELDFVDNLITDDVRNNSAWNQR 601
+EL F D+LIT + N S+W+ R
Sbjct: 160 PAEELAFTDSLITRNFSNYSSWHYR 184
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 14/110 (12%)
Frame = +2
Query: 224 RVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRV 403
R L L LE++ N+ W YRR + EL + +++I + NY WH+R
Sbjct: 127 RELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSSWHYRSC 186
Query: 404 LVEWL-------------QDPTM-ELELTGDALLQDPKNYHAWQHRQWAI 511
L+ L +D + ELEL +A DP + AW + +W +
Sbjct: 187 LLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLL 236
>BC003093-1|AAH03093.1| 567|Homo sapiens Rab
geranylgeranyltransferase, alpha subunit protein.
Length = 567
Score = 89.8 bits (213), Expect = 7e-18
Identities = 53/145 (36%), Positives = 80/145 (55%), Gaps = 12/145 (8%)
Frame = +2
Query: 203 QSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTD---------LRTELDYVEAV 355
Q+ E E VL LT L NP T+W RR++L+ L T ++ EL ++E+
Sbjct: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Query: 356 IKNSPKNYQVWHHRRVLVEWLQDP--TMELELTGDALLQDPKNYHAWQHRQW-AIKTFGL 526
++ +PK+Y WHHR L+ L +P T ELEL L D +N+H W +R++ A +
Sbjct: 100 LRVNPKSYGTWHHRCWLLGRLPEPNWTRELELCARFLEVDERNFHCWDYRRFVATQAAVP 159
Query: 527 YEKELDFVDNLITDDVRNNSAWNQR 601
+EL F D+LIT + N S+W+ R
Sbjct: 160 PAEELAFTDSLITRNFSNYSSWHYR 184
Score = 48.4 bits (110), Expect = 2e-05
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 14/110 (12%)
Frame = +2
Query: 224 RVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRV 403
R L L LE++ N+ W YRR + EL + +++I + NY WH+R
Sbjct: 127 RELELCARFLEVDERNFHCWDYRRFVATQAAVPPAEELAFTDSLITRNFSNYSSWHYRSC 186
Query: 404 LVEWL-------------QDPTM-ELELTGDALLQDPKNYHAWQHRQWAI 511
L+ L +D + ELEL +A DP + AW + +W +
Sbjct: 187 LLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLL 236
>BC053622-1|AAH53622.1| 403|Homo sapiens PTAR1 protein protein.
Length = 403
Score = 44.0 bits (99), Expect = 4e-04
Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 29/162 (17%)
Frame = +2
Query: 221 ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRR 400
+ ++ +T L LNP T W R++L+ + +L + + PK+ + W HRR
Sbjct: 86 DELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRR 145
Query: 401 -VLVEWLQDPTM-----------------------ELELTGDALLQDPKNYHAWQHRQWA 508
VL + +Q+ ++ E+E+ G+A + P NY+AW HR W
Sbjct: 146 WVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWV 205
Query: 509 IKTFGLYE-----KELDFVDNLITDDVRNNSAWNQRYFVVNN 619
++ + EL + + V ++S ++ R F++ +
Sbjct: 206 LQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKS 247
>AL162412-2|CAI10945.2| 312|Homo sapiens protein prenyltransferase
alpha subunit repeat containing 1 protein.
Length = 312
Score = 44.0 bits (99), Expect = 4e-04
Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 29/162 (17%)
Frame = +2
Query: 221 ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRR 400
+ ++ +T L LNP T W R++L+ + +L + + PK+ + W HRR
Sbjct: 85 DELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRR 144
Query: 401 -VLVEWLQDPTM-----------------------ELELTGDALLQDPKNYHAWQHRQWA 508
VL + +Q+ ++ E+E+ G+A + P NY+AW HR W
Sbjct: 145 WVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWV 204
Query: 509 IKTFGLYE-----KELDFVDNLITDDVRNNSAWNQRYFVVNN 619
++ + EL + + V ++S ++ R F++ +
Sbjct: 205 LQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKS 246
>AL162412-1|CAI10944.1| 350|Homo sapiens protein prenyltransferase
alpha subunit repeat containing 1 protein.
Length = 350
Score = 39.5 bits (88), Expect = 0.010
Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 5/135 (3%)
Frame = +2
Query: 230 LHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQVWHHRRVLV 409
LHL K AL P + W +RR +L+ L + T L V K + +R++
Sbjct: 44 LHLGKLALTKFPKSPETWIHRRWVLQQLIQE--TSLP--SFVTKGNLGTIPTERAQRLIQ 99
Query: 410 EWLQDPTMELELTGDALLQDPKNYHAWQHRQWAIKTFGLYE-----KELDFVDNLITDDV 574
E E+E+ G+A + P NY+AW HR W ++ + EL + + V
Sbjct: 100 E-------EMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHV 152
Query: 575 RNNSAWNQRYFVVNN 619
++S ++ R F++ +
Sbjct: 153 SDHSGFHYRQFLLKS 167
Score = 30.7 bits (66), Expect = 4.4
Identities = 12/42 (28%), Positives = 23/42 (54%)
Frame = +2
Query: 389 HHRRVLVEWLQDPTMELELTGDALLQDPKNYHAWQHRQWAIK 514
H + +++ +P +L L AL + PK+ W HR+W ++
Sbjct: 28 HMKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQ 69
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,962,407
Number of Sequences: 237096
Number of extensions: 2196977
Number of successful extensions: 4376
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4066
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4298
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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