Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt10k21
(710 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 211 2e-54
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 211 2e-54
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 211 2e-54
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 211 2e-54
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 211 2e-54
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 211 2e-54
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 208 1e-53
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 208 1e-53
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 208 1e-53
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 202 1e-51
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 200 3e-51
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 176 7e-44
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 176 7e-44
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 176 7e-44
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 171 3e-42
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 171 3e-42
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 171 3e-42
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 171 3e-42
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 153 4e-37
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 103 5e-22
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 103 5e-22
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 103 8e-22
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 87 4e-17
AL359204-2|CAI39538.1| 3174|Homo sapiens vacuolar protein sortin... 30 7.1
AL359204-1|CAI39537.1| 3095|Homo sapiens vacuolar protein sortin... 30 7.1
AL353710-2|CAH74106.1| 3174|Homo sapiens vacuolar protein sortin... 30 7.1
AL353710-1|CAH74105.1| 3095|Homo sapiens vacuolar protein sortin... 30 7.1
AL158159-2|CAI40936.1| 3174|Homo sapiens vacuolar protein sortin... 30 7.1
AL158159-1|CAI40935.1| 3095|Homo sapiens vacuolar protein sortin... 30 7.1
AJ626859-1|CAF25186.1| 3069|Homo sapiens chorein 1D protein. 30 7.1
AJ608769-1|CAE75581.1| 3135|Homo sapiens chorein 2A protein. 30 7.1
AF337532-1|AAK61861.1| 3174|Homo sapiens chorea-acanthocytosis p... 30 7.1
AB054005-1|BAB59128.1| 3095|Homo sapiens chorein protein. 30 7.1
AK128523-1|BAC87477.1| 128|Homo sapiens protein. 30 9.4
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 211 bits (516), Expect = 2e-54
Identities = 88/207 (42%), Positives = 132/207 (63%), Gaps = 1/207 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
++ +LGL HYRFS+SW RLLP G +I++ G +YYN +ID LLKN + P++T+YH++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ +D GGW + I++ F YA +S F DRVK W+T+NE ++ +SY +G+ PG
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 627 LYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ G + +++ AHA++W YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 211 bits (516), Expect = 2e-54
Identities = 88/207 (42%), Positives = 132/207 (63%), Gaps = 1/207 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
++ +LGL HYRFS+SW RLLP G +I++ G +YYN +ID LLKN + P++T+YH++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ +D GGW + I++ F YA +S F DRVK W+T+NE ++ +SY +G+ PG
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 627 LYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ G + +++ AHA++W YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 211 bits (516), Expect = 2e-54
Identities = 88/207 (42%), Positives = 132/207 (63%), Gaps = 1/207 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
++ +LGL HYRFS+SW RLLP G +I++ G +YYN +ID LLKN + P++T+YH++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ +D GGW + I++ F YA +S F DRVK W+T+NE ++ +SY +G+ PG
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 627 LYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ G + +++ AHA++W YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 211 bits (516), Expect = 2e-54
Identities = 88/207 (42%), Positives = 132/207 (63%), Gaps = 1/207 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
++ +LGL HYRFS+SW RLLP G +I++ G +YYN +ID LLKN + P++T+YH++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ +D GGW + I++ F YA +S F DRVK W+T+NE ++ +SY +G+ PG
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 627 LYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ G + +++ AHA++W YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 211 bits (516), Expect = 2e-54
Identities = 88/207 (42%), Positives = 132/207 (63%), Gaps = 1/207 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
++ +LGL HYRFS+SW RLLP G +I++ G +YYN +ID LLKN + P++T+YH++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ +D GGW + I++ F YA +S F DRVK W+T+NE ++ +SY +G+ PG
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 627 LYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ G + +++ AHA++W YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 211 bits (515), Expect = 2e-54
Identities = 88/207 (42%), Positives = 132/207 (63%), Gaps = 1/207 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
++ +LGL HYRFS+SW RLLP G +I++ G +YYN +ID LLKN + P++T+YH++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ +D GGW + I++ F YA +S F DRVK W+T+NE ++ +SY +G+ PG
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 627 LYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ G + +++ AHA++W YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 208 bits (508), Expect = 1e-53
Identities = 98/209 (46%), Positives = 135/209 (64%), Gaps = 2/209 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A S++YQIEGAW KG SI D ++H P +V + + GDVACDSY+ D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
+ LG+ HYRFSISW R+LP G YI+E G NYY LID LL +I+P +TIYH++
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ QD+GGW N IV F +YA V++ D+VK W+T+NEP +I Y G +APG
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 627 LYS-PDHGLFLCNKHVLLAHAKAWRLYDE 710
+ + P ++ +++ AHA+AW LY++
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 200 bits (489), Expect = 3e-51
Identities = 91/209 (43%), Positives = 128/209 (61%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRR 266
TF +F +G SS+YQIEGAW+ KG SI D + H V D + GD+ACDSY+
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 267 DIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHY 446
D+ M L + YRFSISW R+ P+G + I+ G +YYN LI+GL+ +NI P++T++H+
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 447 ELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAP 623
+LPQ QD+GGW NP ++D F YA + F DRVK W+T NEP+ + + Y G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 624 GLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
G+ P + V+ AHA+ + YDE
Sbjct: 1082 GVKDPGWAPYRIAHTVIKAHARVYHTYDE 1110
Score = 162 bits (393), Expect = 1e-39
Identities = 84/212 (39%), Positives = 117/212 (55%), Gaps = 2/212 (0%)
Frame = +3
Query: 78 LEKTFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDG-SNGDVACDSYN 254
L+ TFP F +GA + ++ +EG W +G SI D P +G + +VA DSY+
Sbjct: 378 LQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYH 434
Query: 255 LWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVIT 434
D+ + L Y+FSISW R+ P G+ + S G YYN LID L IEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 435 IYHYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IG 611
++H++LPQ QD GGW N +VD F DYA+ +S F DRVK+W+T +EP ++ Y G
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 612 ISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
PG+ P F VL AHA+ W Y+
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAHARTWHHYN 586
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/95 (29%), Positives = 44/95 (46%)
Frame = +3
Query: 294 LDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYELPQVFQDL 473
+ HY+ +SW +LLP+G E Y L+ L ++P++ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR- 142
Query: 474 GGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
D FADYA+ + F D V IW T ++
Sbjct: 143 ---RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 208 bits (508), Expect = 1e-53
Identities = 98/209 (46%), Positives = 135/209 (64%), Gaps = 2/209 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A S++YQIEGAW KG SI D ++H P +V + + GDVACDSY+ D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
+ LG+ HYRFSISW R+LP G YI+E G NYY LID LL +I+P +TIYH++
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ QD+GGW N IV F +YA V++ D+VK W+T+NEP +I Y G +APG
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 627 LYS-PDHGLFLCNKHVLLAHAKAWRLYDE 710
+ + P ++ +++ AHA+AW LY++
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 200 bits (489), Expect = 3e-51
Identities = 91/209 (43%), Positives = 128/209 (61%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRR 266
TF +F +G SS+YQIEGAW+ KG SI D + H V D + GD+ACDSY+
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 267 DIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHY 446
D+ M L + YRFSISW R+ P+G + I+ G +YYN LI+GL+ +NI P++T++H+
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 447 ELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAP 623
+LPQ QD+GGW NP ++D F YA + F DRVK W+T NEP+ + + Y G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 624 GLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
G+ P + V+ AHA+ + YDE
Sbjct: 1082 GVKDPGWAPYRIAHAVIKAHARVYHTYDE 1110
Score = 162 bits (393), Expect = 1e-39
Identities = 84/212 (39%), Positives = 117/212 (55%), Gaps = 2/212 (0%)
Frame = +3
Query: 78 LEKTFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDG-SNGDVACDSYN 254
L+ TFP F +GA + ++ +EG W +G SI D P +G + +VA DSY+
Sbjct: 378 LQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYH 434
Query: 255 LWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVIT 434
D+ + L Y+FSISW R+ P G+ + S G YYN LID L IEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 435 IYHYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IG 611
++H++LPQ QD GGW N +VD F DYA+ +S F DRVK+W+T +EP ++ Y G
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 612 ISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
PG+ P F VL AHA+ W Y+
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAHARTWHHYN 586
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/95 (29%), Positives = 44/95 (46%)
Frame = +3
Query: 294 LDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYELPQVFQDL 473
+ HY+ +SW +LLP+G E Y L+ L ++P++ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR- 142
Query: 474 GGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
D FADYA+ + F D V IW T ++
Sbjct: 143 ---RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 208 bits (508), Expect = 1e-53
Identities = 98/209 (46%), Positives = 135/209 (64%), Gaps = 2/209 (0%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A S++YQIEGAW KG SI D ++H P +V + + GDVACDSY+ D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
+ LG+ HYRFSISW R+LP G YI+E G NYY LID LL +I+P +TIYH++
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAPG 626
LPQ QD+GGW N IV F +YA V++ D+VK W+T+NEP +I Y G +APG
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 627 LYS-PDHGLFLCNKHVLLAHAKAWRLYDE 710
+ + P ++ +++ AHA+AW LY++
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 200 bits (489), Expect = 3e-51
Identities = 91/209 (43%), Positives = 128/209 (61%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRR 266
TF +F +G SS+YQIEGAW+ KG SI D + H V D + GD+ACDSY+
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 267 DIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHY 446
D+ M L + YRFSISW R+ P+G + I+ G +YYN LI+GL+ +NI P++T++H+
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 447 ELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAP 623
+LPQ QD+GGW NP ++D F YA + F DRVK W+T NEP+ + + Y G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 624 GLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
G+ P + V+ AHA+ + YDE
Sbjct: 1082 GVKDPGWAPYRIAHAVIKAHARVYHTYDE 1110
Score = 162 bits (393), Expect = 1e-39
Identities = 84/212 (39%), Positives = 117/212 (55%), Gaps = 2/212 (0%)
Frame = +3
Query: 78 LEKTFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDG-SNGDVACDSYN 254
L+ TFP F +GA + ++ +EG W +G SI D P +G + +VA DSY+
Sbjct: 378 LQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYH 434
Query: 255 LWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVIT 434
D+ + L Y+FSISW R+ P G+ + S G YYN LID L IEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 435 IYHYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IG 611
++H++LPQ QD GGW N +VD F DYA+ +S F DRVK+W+T +EP ++ Y G
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 612 ISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
PG+ P F VL AHA+ W Y+
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAHARTWHHYN 586
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/95 (29%), Positives = 44/95 (46%)
Frame = +3
Query: 294 LDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYELPQVFQDL 473
+ HY+ +SW +LLP+G E Y L+ L ++P++ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR- 142
Query: 474 GGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
D FADYA+ + F D V IW T ++
Sbjct: 143 ---RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 202 bits (493), Expect = 1e-51
Identities = 93/210 (44%), Positives = 133/210 (63%), Gaps = 3/210 (1%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRR 266
TFPL F +G GSS+YQ EGAW+ KG SI D + H KV+ DVACD Y +
Sbjct: 36 TFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQE 95
Query: 267 DIEMATELGLDHYRFSISWPRLLPSGY-PNYISEDGRNYYNNLIDGLLKNNIEPVITIYH 443
DI + EL ++HYRFS+SWPRLLP+G +++ G +Y++LID LL +NI P++T++H
Sbjct: 96 DIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHH 155
Query: 444 YELPQVFQ-DLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGIS 617
++LPQ+ Q GGW N + ++F DYA++ + F DRVK W+T ++P + + Y G
Sbjct: 156 WDLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHH 215
Query: 618 APGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
APGL GL+ H++ AHAK W Y+
Sbjct: 216 APGLKLRGTGLYKAAHHIIKAHAKTWHSYN 245
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 200 bits (489), Expect = 3e-51
Identities = 91/209 (43%), Positives = 128/209 (61%), Gaps = 1/209 (0%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRR 266
TF +F +G SS+YQIEGAW+ KG SI D + H V D + GD+ACDSY+
Sbjct: 334 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 393
Query: 267 DIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHY 446
D+ M L + YRFSISW R+ P+G + I+ G +YYN LI+GL+ +NI P++T++H+
Sbjct: 394 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 453
Query: 447 ELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IGISAP 623
+LPQ QD+GGW NP ++D F YA + F DRVK W+T NEP+ + + Y G P
Sbjct: 454 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 513
Query: 624 GLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
G+ P + V+ AHA+ + YDE
Sbjct: 514 GVKDPGWAPYRIAHTVIKAHARVYHTYDE 542
Score = 192 bits (468), Expect = 1e-48
Identities = 91/193 (47%), Positives = 120/193 (62%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A S++YQIEGAW KG SI D ++H P +V + + GDVACDSY+ D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 867
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITIYHYE 449
+ LG+ HYRFSISW R+LP G YI+E G NYY LID LL +I+P +TIYH++
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 450 LPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSYIGISAPGL 629
LPQ QD+GGW N IV F +YA V++ D+VK W+T+NEP +I Y G
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGY----GYGT 983
Query: 630 YSPDHGLFLCNKH 668
+P HG +C +
Sbjct: 984 AAPVHGRLVCTSY 996
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 176 bits (428), Expect = 7e-44
Identities = 83/212 (39%), Positives = 123/212 (58%), Gaps = 2/212 (0%)
Frame = +3
Query: 78 LEKTFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNL 257
L TFP NF +G G+ + Q+EG+W KG SI D + H H K V +NG + DSY
Sbjct: 77 LYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHL-KNVSSTNG--SSDSYIF 133
Query: 258 WRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITI 437
+D+ +G+ Y+FSISWPRL P G + G YY+ L+D L+ NIEP++T+
Sbjct: 134 LEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTL 193
Query: 438 YHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IG 611
YH++LP Q+ GGW N I+D F DYA+ + +F DRVK W+T++ P ++ Y G
Sbjct: 194 YHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTG 253
Query: 612 ISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ APG ++ +++ AH+K W Y+
Sbjct: 254 MHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 95.5 bits (227), Expect = 2e-19
Identities = 51/161 (31%), Positives = 79/161 (49%), Gaps = 5/161 (3%)
Frame = +3
Query: 240 CDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNI 419
C + ++ +EM + + HYRF++ W +LP+G + ++ YY ++ LK I
Sbjct: 576 CTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGI 635
Query: 420 EPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPL 584
++T+Y H LP+ GW NP + F YA + + D VK+W+T+NEP
Sbjct: 636 SAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPN 695
Query: 585 IICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ D+ S Y H L L+AHA AWRLYD
Sbjct: 696 RLSDI--YNRSGNDTYGAAHNL-------LVAHALAWRLYD 727
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 176 bits (428), Expect = 7e-44
Identities = 83/212 (39%), Positives = 123/212 (58%), Gaps = 2/212 (0%)
Frame = +3
Query: 78 LEKTFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNL 257
L TFP NF +G G+ + Q+EG+W KG SI D + H H K V +NG + DSY
Sbjct: 77 LYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHL-KNVSSTNG--SSDSYIF 133
Query: 258 WRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITI 437
+D+ +G+ Y+FSISWPRL P G + G YY+ L+D L+ NIEP++T+
Sbjct: 134 LEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTL 193
Query: 438 YHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IG 611
YH++LP Q+ GGW N I+D F DYA+ + +F DRVK W+T++ P ++ Y G
Sbjct: 194 YHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTG 253
Query: 612 ISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ APG ++ +++ AH+K W Y+
Sbjct: 254 MHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 95.5 bits (227), Expect = 2e-19
Identities = 51/161 (31%), Positives = 79/161 (49%), Gaps = 5/161 (3%)
Frame = +3
Query: 240 CDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNI 419
C + ++ +EM + + HYRF++ W +LP+G + ++ YY ++ LK I
Sbjct: 576 CTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGI 635
Query: 420 EPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPL 584
++T+Y H LP+ GW NP + F YA + + D VK+W+T+NEP
Sbjct: 636 SAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPN 695
Query: 585 IICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ D+ S Y H L L+AHA AWRLYD
Sbjct: 696 RLSDI--YNRSGNDTYGAAHNL-------LVAHALAWRLYD 727
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 176 bits (428), Expect = 7e-44
Identities = 83/212 (39%), Positives = 123/212 (58%), Gaps = 2/212 (0%)
Frame = +3
Query: 78 LEKTFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNL 257
L TFP NF +G G+ + Q+EG+W KG SI D + H H K V +NG + DSY
Sbjct: 77 LYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHL-KNVSSTNG--SSDSYIF 133
Query: 258 WRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNIEPVITI 437
+D+ +G+ Y+FSISWPRL P G + G YY+ L+D L+ NIEP++T+
Sbjct: 134 LEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTL 193
Query: 438 YHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPLIICDVSY-IG 611
YH++LP Q+ GGW N I+D F DYA+ + +F DRVK W+T++ P ++ Y G
Sbjct: 194 YHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTG 253
Query: 612 ISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ APG ++ +++ AH+K W Y+
Sbjct: 254 MHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 95.5 bits (227), Expect = 2e-19
Identities = 51/161 (31%), Positives = 79/161 (49%), Gaps = 5/161 (3%)
Frame = +3
Query: 240 CDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLKNNI 419
C + ++ +EM + + HYRF++ W +LP+G + ++ YY ++ LK I
Sbjct: 576 CTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGI 635
Query: 420 EPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNEPL 584
++T+Y H LP+ GW NP + F YA + + D VK+W+T+NEP
Sbjct: 636 SAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPN 695
Query: 585 IICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
+ D+ S Y H L L+AHA AWRLYD
Sbjct: 696 RLSDI--YNRSGNDTYGAAHNL-------LVAHALAWRLYD 727
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 171 bits (415), Expect = 3e-42
Identities = 90/224 (40%), Positives = 122/224 (54%), Gaps = 17/224 (7%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSN------------- 227
TFP F + GS++YQ EG W KG SI D + H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 228 --GDVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDG 401
GDVA DSYN RD E ELG+ HYRFSISW R+LP+G + +G YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 402 LLKNNIEPVITIYHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
L + ++PV+T+YH++LPQ QD GGW N + D F DYA + + F +VK W+T++
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 579 PLIICDVSY-IGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
P ++ Y G APG+ +L ++LLAHAK W LY+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 87.4 bits (207), Expect = 4e-17
Identities = 63/225 (28%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Frame = +3
Query: 63 PVRRPLEKTFPLNFKFGAGSSSYQIEGAWN-VSDKGESIQDRYAHEHPEKVVDG---SNG 230
P +PLE TFP +F +G + Q++ + +D + D + + KV DG
Sbjct: 510 PENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKV-DGVVTKKR 568
Query: 231 DVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLK 410
C + + I + E+ + H+RFS+ W +LP G + ++ YY + L++
Sbjct: 569 KSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVR 628
Query: 411 NNIEPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVN 575
NI PV+ ++ + LP++ G W NP FA+YA + + VK+W+T+N
Sbjct: 629 VNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMN 688
Query: 576 EPLIICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
EP + YS H L L AHA AW +Y+E
Sbjct: 689 EP----------YTRNMTYSAGHNL-------LKAHALAWHVYNE 716
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 171 bits (415), Expect = 3e-42
Identities = 90/224 (40%), Positives = 122/224 (54%), Gaps = 17/224 (7%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSN------------- 227
TFP F + GS++YQ EG W KG SI D + H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 228 --GDVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDG 401
GDVA DSYN RD E ELG+ HYRFSISW R+LP+G + +G YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 402 LLKNNIEPVITIYHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
L + ++PV+T+YH++LPQ QD GGW N + D F DYA + + F +VK W+T++
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 579 PLIICDVSY-IGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
P ++ Y G APG+ +L ++LLAHAK W LY+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 171 bits (415), Expect = 3e-42
Identities = 90/224 (40%), Positives = 122/224 (54%), Gaps = 17/224 (7%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSN------------- 227
TFP F + GS++YQ EG W KG SI D + H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 228 --GDVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDG 401
GDVA DSYN RD E ELG+ HYRFSISW R+LP+G + +G YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 402 LLKNNIEPVITIYHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
L + ++PV+T+YH++LPQ QD GGW N + D F DYA + + F +VK W+T++
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 579 PLIICDVSY-IGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
P ++ Y G APG+ +L ++LLAHAK W LY+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 87.4 bits (207), Expect = 4e-17
Identities = 63/225 (28%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Frame = +3
Query: 63 PVRRPLEKTFPLNFKFGAGSSSYQIEGAWN-VSDKGESIQDRYAHEHPEKVVDG---SNG 230
P +PLE TFP +F +G + Q++ + +D + D + + KV DG
Sbjct: 510 PENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKV-DGVVTKKR 568
Query: 231 DVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLK 410
C + + I + E+ + H+RFS+ W +LP G + ++ YY + L++
Sbjct: 569 KSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVR 628
Query: 411 NNIEPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVN 575
NI PV+ ++ + LP++ G W NP FA+YA + + VK+W+T+N
Sbjct: 629 VNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMN 688
Query: 576 EPLIICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
EP + YS H L L AHA AW +Y+E
Sbjct: 689 EP----------YTRNMTYSAGHNL-------LKAHALAWHVYNE 716
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 171 bits (415), Expect = 3e-42
Identities = 90/224 (40%), Positives = 122/224 (54%), Gaps = 17/224 (7%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSN------------- 227
TFP F + GS++YQ EG W KG SI D + H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 228 --GDVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDG 401
GDVA DSYN RD E ELG+ HYRFSISW R+LP+G + +G YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 402 LLKNNIEPVITIYHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
L + ++PV+T+YH++LPQ QD GGW N + D F DYA + + F +VK W+T++
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 579 PLIICDVSY-IGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYD 707
P ++ Y G APG+ +L ++LLAHAK W LY+
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 87.4 bits (207), Expect = 4e-17
Identities = 63/225 (28%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Frame = +3
Query: 63 PVRRPLEKTFPLNFKFGAGSSSYQIEGAWN-VSDKGESIQDRYAHEHPEKVVDG---SNG 230
P +PLE TFP +F +G + Q++ + +D + D + + KV DG
Sbjct: 510 PENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKV-DGVVTKKR 568
Query: 231 DVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLK 410
C + + I + E+ + H+RFS+ W +LP G + ++ YY + L++
Sbjct: 569 KSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVR 628
Query: 411 NNIEPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVN 575
NI PV+ ++ + LP++ G W NP FA+YA + + VK+W+T+N
Sbjct: 629 VNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMN 688
Query: 576 EPLIICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
EP + YS H L L AHA AW +Y+E
Sbjct: 689 EP----------YTRNMTYSAGHNL-------LKAHALAWHVYNE 716
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 153 bits (372), Expect = 4e-37
Identities = 84/214 (39%), Positives = 115/214 (53%), Gaps = 18/214 (8%)
Frame = +3
Query: 87 TFPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSN------------- 227
TFP F + GS++YQ EG W KG SI D + H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 228 --GDVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDG 401
GDVA DSYN RD E ELG+ HYRFSISW R+LP+G + +G YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 402 LLKNNIEPVITIYHYELPQVFQD-LGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVNE 578
L + ++PV+T+YH++LPQ QD GGW N + D F DYA + + F +VK W+T++
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 579 PLIICDVSY-IGISAPGLY-SPDHGLFLCNKHVL 674
P ++ Y G APG+ SP G + + +L
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 5e-22
Identities = 41/92 (44%), Positives = 58/92 (63%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISE 365
++ +LGL HYRFS+SW RLLP G +I++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 5e-22
Identities = 41/92 (44%), Positives = 58/92 (63%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISE 365
++ +LGL HYRFS+SW RLLP G +I++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (246), Expect = 8e-22
Identities = 41/92 (44%), Positives = 58/92 (63%)
Frame = +3
Query: 90 FPLNFKFGAGSSSYQIEGAWNVSDKGESIQDRYAHEHPEKVVDGSNGDVACDSYNLWRRD 269
FP F + A +++YQ+EG W+ KG + D + H+ E+V GDVAC SY LW D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 270 IEMATELGLDHYRFSISWPRLLPSGYPNYISE 365
++ +LGL HYRFS+SW RLLP G +I++
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 87.4 bits (207), Expect = 4e-17
Identities = 63/225 (28%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Frame = +3
Query: 63 PVRRPLEKTFPLNFKFGAGSSSYQIEGAWN-VSDKGESIQDRYAHEHPEKVVDG---SNG 230
P +PLE TFP +F +G + Q++ + +D + D + + KV DG
Sbjct: 237 PENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKV-DGVVTKKR 295
Query: 231 DVACDSYNLWRRDIEMATELGLDHYRFSISWPRLLPSGYPNYISEDGRNYYNNLIDGLLK 410
C + + I + E+ + H+RFS+ W +LP G + ++ YY + L++
Sbjct: 296 KSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVR 355
Query: 411 NNIEPVITIY-----HYELPQVFQDLGGWTNPLIVDWFADYASVVYSLFADRVKIWLTVN 575
NI PV+ ++ + LP++ G W NP FA+YA + + VK+W+T+N
Sbjct: 356 VNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMN 415
Query: 576 EPLIICDVSYIGISAPGLYSPDHGLFLCNKHVLLAHAKAWRLYDE 710
EP + YS H L L AHA AW +Y+E
Sbjct: 416 EP----------YTRNMTYSAGHNL-------LKAHALAWHVYNE 443
>AL359204-2|CAI39538.1| 3174|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3174
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AL359204-1|CAI39537.1| 3095|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3095
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AL353710-2|CAH74106.1| 3174|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3174
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AL353710-1|CAH74105.1| 3095|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3095
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AL158159-2|CAI40936.1| 3174|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3174
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AL158159-1|CAI40935.1| 3095|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3095
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AJ626859-1|CAF25186.1| 3069|Homo sapiens chorein 1D protein.
Length = 3069
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AJ608769-1|CAE75581.1| 3135|Homo sapiens chorein 2A protein.
Length = 3135
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AF337532-1|AAK61861.1| 3174|Homo sapiens chorea-acanthocytosis
protein.
Length = 3174
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AB054005-1|BAB59128.1| 3095|Homo sapiens chorein protein.
Length = 3095
Score = 30.3 bits (65), Expect = 7.1
Identities = 11/39 (28%), Positives = 26/39 (66%)
Frame = -3
Query: 207 SLDVHEHSDPVCSHLYH*HSMRPRSDTTTNPLQT*SSEE 91
SLD+H H++ + + + + H++ P+S+ + P+ T +E+
Sbjct: 993 SLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETED 1031
>AK128523-1|BAC87477.1| 128|Homo sapiens protein.
Length = 128
Score = 29.9 bits (64), Expect = 9.4
Identities = 13/44 (29%), Positives = 18/44 (40%)
Frame = +1
Query: 184 AMLMNIQRKWLTAAMVTSPATPTTFGGGTSKWPLNWDWIIIDSP 315
A L R WL + + G KWP +W W++I P
Sbjct: 33 AALKESHRSWLMCCGDSVAPFHSQIVGRNLKWPASWTWLVIIFP 76
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,954,744
Number of Sequences: 237096
Number of extensions: 2459582
Number of successful extensions: 5755
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 5442
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5694
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8287202872
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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