BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= bmmt10k18 (727 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000E498BD Cluster: PREDICTED: similar to Carbonyl r... 118 1e-25 UniRef50_O97166 Cluster: 3-alpha-hydroxysteroid dehydrogenase-li... 100 3e-20 UniRef50_A7RGK5 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 94 4e-18 UniRef50_A7SF98 Cluster: Predicted protein; n=1; Nematostella ve... 89 1e-16 UniRef50_UPI0000E494E7 Cluster: PREDICTED: similar to Carbonyl r... 86 7e-16 UniRef50_UPI0000E47A47 Cluster: PREDICTED: similar to serum lect... 82 1e-14 UniRef50_UPI0000E46681 Cluster: PREDICTED: similar to carbonyl r... 82 1e-14 UniRef50_P16152 Cluster: Carbonyl reductase [NADPH] 1 (EC 1.1.1.... 73 5e-12 UniRef50_Q5DEH8 Cluster: SJCHGC00683 protein; n=2; Schistosoma|R... 67 5e-10 UniRef50_Q501A2 Cluster: At5g61830; n=8; Magnoliophyta|Rep: At5g... 66 1e-09 UniRef50_UPI000155BDDB Cluster: PREDICTED: similar to NADP+ depe... 64 3e-09 UniRef50_A3WIM4 Cluster: Putative dehydrogenase; n=1; Idiomarina... 62 1e-08 UniRef50_Q6H7C9 Cluster: Short-chain dehydrogenase/reductase pro... 62 2e-08 UniRef50_A0BRV4 Cluster: Chromosome undetermined scaffold_123, w... 60 5e-08 UniRef50_Q097P7 Cluster: Carbonyl reductase [NADPH] 1 (Nadph-dep... 59 1e-07 UniRef50_Q7NNW5 Cluster: Glr0293 protein; n=6; Bacteria|Rep: Glr... 58 2e-07 UniRef50_A6CM25 Cluster: Oxidoreductase, short chain dehydrogena... 58 2e-07 UniRef50_UPI0000E476E0 Cluster: PREDICTED: similar to Carbonyl r... 58 2e-07 UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 58 2e-07 UniRef50_A4X6Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 58 2e-07 UniRef50_Q01IF3 Cluster: H0306B06.2 protein; n=15; Magnoliophyta... 57 5e-07 UniRef50_A5FMQ3 Cluster: Short-chain dehydrogenase/reductase SDR... 56 7e-07 UniRef50_Q9LQ75 Cluster: T1N6.22 protein; n=13; core eudicotyled... 56 9e-07 UniRef50_Q233Z6 Cluster: Oxidoreductase, short chain dehydrogena... 55 2e-06 UniRef50_A7PQQ5 Cluster: Chromosome chr6 scaffold_25, whole geno... 54 3e-06 UniRef50_Q140F5 Cluster: Putative short-chain dehydrogenase/oxid... 54 4e-06 UniRef50_Q97SL2 Cluster: Oxidoreductase, short chain dehydrogena... 53 6e-06 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 53 6e-06 UniRef50_Q08MV7 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 53 8e-06 UniRef50_A1ZM53 Cluster: Short chain dehydrogenase; n=1; Microsc... 52 1e-05 UniRef50_A1FW82 Cluster: Short-chain dehydrogenase/reductase SDR... 52 1e-05 UniRef50_Q00RH9 Cluster: OSIGBa0125M19.7 protein; n=12; Oryza sa... 52 1e-05 UniRef50_Q8YZV3 Cluster: NADPH-dependent carbonyl reductase; n=5... 52 2e-05 UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrob... 52 2e-05 UniRef50_Q1QYL7 Cluster: Short-chain dehydrogenase/reductase SDR... 51 3e-05 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 51 3e-05 UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 51 3e-05 UniRef50_Q89PU2 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 50 4e-05 UniRef50_Q3A5G9 Cluster: Short-chain alcohol dehydrogenase-like ... 50 4e-05 UniRef50_Q00RH3 Cluster: OSIGBa0125M19.13 protein; n=9; Oryza sa... 50 6e-05 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 50 8e-05 UniRef50_A0M4X9 Cluster: Short-chain dehydrogenase/reductase fam... 50 8e-05 UniRef50_A0E1K9 Cluster: Chromosome undetermined scaffold_73, wh... 50 8e-05 UniRef50_UPI0000E47390 Cluster: PREDICTED: similar to retinol de... 49 1e-04 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 49 1e-04 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 49 1e-04 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 49 1e-04 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 49 1e-04 UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 48 2e-04 UniRef50_Q6SFN3 Cluster: Oxidoreductase, short chain dehydrogena... 48 2e-04 UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re... 48 2e-04 UniRef50_A5B040 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04 UniRef50_Q6MHI6 Cluster: Short chain dehydrogenase; n=1; Bdellov... 48 3e-04 UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 48 3e-04 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 48 3e-04 UniRef50_A7QKE7 Cluster: Chromosome chr2 scaffold_112, whole gen... 48 3e-04 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 48 3e-04 UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 47 4e-04 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 47 4e-04 UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR... 47 5e-04 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 47 5e-04 UniRef50_Q6H7D1 Cluster: Short-chain dehydrogenase/reductase pro... 47 5e-04 UniRef50_Q4U978 Cluster: Short-chain dehydrogenase/reductase (SD... 47 5e-04 UniRef50_Q2UT07 Cluster: Dehydrogenases with different specifici... 47 5e-04 UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 47 5e-04 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 46 7e-04 UniRef50_Q13GU3 Cluster: Putative short-chain dehydrogenase/redu... 46 7e-04 UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR... 46 7e-04 UniRef50_A3XJH6 Cluster: D-mannonate oxidoreductase; n=7; Bacter... 46 7e-04 UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 46 7e-04 UniRef50_A0YGX3 Cluster: Putative 3-oxoacyl-[ACP] reductase; n=1... 46 7e-04 UniRef50_Q7XIR1 Cluster: Carbonyl reductase-like protein; n=5; M... 46 7e-04 UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;... 46 7e-04 UniRef50_Q5UX46 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 46 0.001 UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena... 46 0.001 UniRef50_Q6SHU1 Cluster: Oxidoreductase, short-chain dehydrogena... 46 0.001 UniRef50_Q1NAB3 Cluster: Short-chain dehydrogenase/reductase SDR... 46 0.001 UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR... 46 0.001 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 45 0.002 UniRef50_Q1ITR9 Cluster: Short-chain dehydrogenase/reductase SDR... 45 0.002 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 45 0.002 UniRef50_Q0UAH4 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 45 0.002 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 45 0.002 UniRef50_Q2JGQ2 Cluster: Short-chain dehydrogenase/reductase SDR... 45 0.002 UniRef50_A1ZT55 Cluster: Carbonyl reductase, NADPH 1; n=1; Micro... 45 0.002 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 45 0.002 UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 45 0.002 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 44 0.003 UniRef50_A7CNG7 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.003 UniRef50_A6Q6X0 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 44 0.003 UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.003 UniRef50_A7PZ82 Cluster: Chromosome chr15 scaffold_40, whole gen... 44 0.003 UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.003 UniRef50_Q39A34 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.004 UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 44 0.004 UniRef50_A6WFA8 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.004 UniRef50_A6EJT9 Cluster: Putative dehydrogenase; n=1; Pedobacter... 44 0.004 UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.004 UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 44 0.004 UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 44 0.004 UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 44 0.004 UniRef50_Q22DT5 Cluster: Oxidoreductase, short chain dehydrogena... 44 0.004 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.004 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 44 0.004 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 44 0.005 UniRef50_Q46N54 Cluster: NAD-dependent epimerase/dehydratase:Sho... 44 0.005 UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena... 44 0.005 UniRef50_A3ZTM1 Cluster: Probable short-chain dehydrogenase; n=1... 44 0.005 UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; ... 44 0.005 UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici... 44 0.005 UniRef50_Q0CE63 Cluster: Predicted protein; n=2; Pezizomycotina|... 44 0.005 UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogena... 44 0.005 UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R... 44 0.005 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 43 0.007 UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 43 0.007 UniRef50_Q026V1 Cluster: Transcriptional regulator, Fis family; ... 43 0.007 UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.007 UniRef50_A6EJ86 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.007 UniRef50_A5FCD6 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.007 UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopire... 43 0.007 UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.007 UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=... 43 0.007 UniRef50_Q89QA5 Cluster: Oxidoreductase; n=4; Alphaproteobacteri... 43 0.009 UniRef50_Q6N3Z1 Cluster: Putative oxidoreductase, short-chain de... 43 0.009 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.009 UniRef50_A7IE62 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.009 UniRef50_A4B7Y2 Cluster: 20-beta-hydroxysteroid dehydrogenase; n... 43 0.009 UniRef50_A1UGA4 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.009 UniRef50_A0GP81 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.009 UniRef50_Q4D5D5 Cluster: Short chain dehydrogenase, putative; n=... 43 0.009 UniRef50_P42317 Cluster: Uncharacterized oxidoreductase yxjF; n=... 43 0.009 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 42 0.012 UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR... 42 0.012 UniRef50_A6GH96 Cluster: Putative short-chain dehydrogenase/redu... 42 0.012 UniRef50_A6D9G4 Cluster: Putative short-chain dehydrogenase/redu... 42 0.012 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 42 0.012 UniRef50_A1ZQT0 Cluster: Dehydrogenase/ reductase 1; n=1; Micros... 42 0.012 UniRef50_A2QKU0 Cluster: Contig An05c0050, complete genome; n=3;... 42 0.012 UniRef50_Q4J702 Cluster: Oxidoreductase; n=2; Sulfolobus|Rep: Ox... 42 0.012 UniRef50_P40580 Cluster: Uncharacterized oxidoreductase YIR036C;... 42 0.012 UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 42 0.012 UniRef50_Q9KCQ9 Cluster: Oxidoreductase; n=10; Firmicutes|Rep: O... 42 0.016 UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 42 0.016 UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al... 42 0.016 UniRef50_Q03B39 Cluster: Carbonyl reductase; n=2; Bacilli|Rep: C... 42 0.016 UniRef50_A3EPN7 Cluster: Putative short-chain alcohol dehydrogen... 42 0.016 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 42 0.016 UniRef50_UPI0000D5685B Cluster: PREDICTED: similar to CG31235-PA... 42 0.021 UniRef50_A3K7W9 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 42 0.021 UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 42 0.021 UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 42 0.021 UniRef50_Q9XVS9 Cluster: Putative uncharacterized protein dhs-22... 42 0.021 UniRef50_UPI000049A4BD Cluster: short chain dehydrogenase family... 41 0.027 UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str... 41 0.027 UniRef50_Q1V1U2 Cluster: FabG-like protein; n=2; Candidatus Pela... 41 0.027 UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 41 0.027 UniRef50_A4BUN6 Cluster: Short-chain dehydrogenase/reductase SDR... 41 0.027 UniRef50_A0G5F7 Cluster: Short-chain dehydrogenase/reductase SDR... 41 0.027 UniRef50_A7RWI1 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.027 UniRef50_Q0V189 Cluster: Putative uncharacterized protein; n=1; ... 41 0.027 UniRef50_UPI00015B6097 Cluster: PREDICTED: similar to CG11200-PA... 41 0.036 UniRef50_Q88ZF7 Cluster: Short-chain dehydrogenase/oxidoreductas... 41 0.036 UniRef50_Q46NA6 Cluster: NAD-dependent epimerase/dehydratase:Sho... 41 0.036 UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 41 0.036 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 41 0.036 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 41 0.036 UniRef50_Q9SY73 Cluster: F14N23.19; n=5; Magnoliophyta|Rep: F14N... 41 0.036 UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 41 0.036 UniRef50_Q6BVQ9 Cluster: Debaryomyces hansenii chromosome C of s... 41 0.036 UniRef50_Q4WZ51 Cluster: Short chain dehydrogenase family protei... 41 0.036 UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ... 41 0.036 UniRef50_Q0CF34 Cluster: Putative uncharacterized protein; n=1; ... 41 0.036 UniRef50_A2R3R8 Cluster: Contig An14c0180, complete genome; n=3;... 41 0.036 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 41 0.036 UniRef50_Q39VG0 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.047 UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.047 UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.047 UniRef50_Q0K556 Cluster: Short chain dehydrogenase; n=1; Ralston... 40 0.047 UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.047 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.047 UniRef50_UPI000038DA8A Cluster: COG1028: Dehydrogenases with dif... 40 0.063 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 40 0.063 UniRef50_Q4L7K1 Cluster: Similar to 3(or 17)beta-hydroxysteroid ... 40 0.063 UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.063 UniRef50_Q2J935 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.063 UniRef50_Q9WWC0 Cluster: AtsC; n=3; Agrobacterium tumefaciens|Re... 40 0.063 UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogena... 40 0.063 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.063 UniRef50_Q0K0G0 Cluster: Short chain dehydrogenase; n=2; Bacteri... 40 0.063 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 40 0.063 UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 40 0.063 UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 40 0.063 UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.063 UniRef50_Q75JB9 Cluster: Similar to Lactococcus lactis (Subsp. l... 40 0.063 UniRef50_Q176N3 Cluster: Short-chain dehydrogenase; n=3; Culicid... 40 0.063 UniRef50_P50200 Cluster: NADP-dependent 7-alpha-hydroxysteroid d... 40 0.063 UniRef50_Q98H76 Cluster: Short chain dehydrogenase; n=3; Mesorhi... 40 0.083 UniRef50_Q8UJN8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 40 0.083 UniRef50_Q5KZI9 Cluster: Dehydrogenase; n=5; Bacilli|Rep: Dehydr... 40 0.083 UniRef50_Q47QD3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 40 0.083 UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 40 0.083 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.083 UniRef50_A6DTR6 Cluster: FabG; n=1; Lentisphaera araneosa HTCC21... 40 0.083 UniRef50_A1UP20 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.083 UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 39 0.11 UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 39 0.11 UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 39 0.11 UniRef50_Q0FSI1 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 39 0.11 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 39 0.11 UniRef50_A1SET6 Cluster: Short-chain dehydrogenase/reductase SDR... 39 0.11 UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 39 0.11 UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bact... 39 0.11 UniRef50_Q2CJB6 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 39 0.14 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 39 0.14 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 39 0.14 UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR... 39 0.14 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 39 0.14 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 39 0.14 UniRef50_Q8G6W8 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 38 0.19 UniRef50_Q62JY9 Cluster: Acetoacetyl-CoA reductase; n=58; cellul... 38 0.19 UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 38 0.19 UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.19 UniRef50_Q1IP06 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.19 UniRef50_Q10XK9 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.19 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 38 0.19 UniRef50_Q039Y3 Cluster: Short-chain alcohol dehydrogenase; n=1;... 38 0.19 UniRef50_A6QK68 Cluster: Oxidoreductase; n=12; Staphylococcus au... 38 0.19 UniRef50_A4AEV0 Cluster: Short chain dehydrogenase; n=1; marine ... 38 0.19 UniRef50_A3YFY3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 38 0.19 UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.19 UniRef50_Q5AWR2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.19 UniRef50_Q1DT84 Cluster: Putative uncharacterized protein; n=1; ... 38 0.19 UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=... 38 0.19 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 38 0.19 UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 38 0.25 UniRef50_Q98K81 Cluster: Oxidoreductase of short-chain; n=4; Bac... 38 0.25 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 38 0.25 UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 38 0.25 UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_A4A504 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_A3Q491 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_A2RHM7 Cluster: Oxidoreductase dltE; n=3; Lactococcus l... 38 0.25 UniRef50_Q4WGC3 Cluster: Short chain dehydrogenase/reductase fam... 38 0.25 UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.25 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 38 0.25 UniRef50_UPI00006CBD6F Cluster: oxidoreductase, short chain dehy... 38 0.33 UniRef50_Q2JY89 Cluster: Putative short chain dehydrogenase prot... 38 0.33 UniRef50_Q2G758 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 38 0.33 UniRef50_A6CZ65 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_A6C8Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_A5L8A4 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_A1UM67 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_A1G528 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_A0K1M9 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.33 UniRef50_Q23EB6 Cluster: Cation channel family protein; n=1; Tet... 38 0.33 UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.33 UniRef50_A0D206 Cluster: Chromosome undetermined scaffold_35, wh... 38 0.33 UniRef50_Q9RI66 Cluster: Putative oxidoreductase; n=1; Streptomy... 37 0.44 UniRef50_Q8YQD6 Cluster: Alr3897 protein; n=2; Nostocaceae|Rep: ... 37 0.44 UniRef50_Q88J66 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 37 0.44 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 37 0.44 UniRef50_Q74T42 Cluster: Gluconate 5-dehydrogenase; n=17; Gammap... 37 0.44 UniRef50_Q0RTK3 Cluster: Putative Short-chain dehydrogenase/redu... 37 0.44 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.44 UniRef50_Q2TW48 Cluster: Dehydrogenases with different specifici... 37 0.44 UniRef50_A5DBZ1 Cluster: Putative uncharacterized protein; n=1; ... 37 0.44 UniRef50_A5YSC3 Cluster: Probable short chanin dehydrogenase/red... 37 0.44 UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein,... 37 0.58 UniRef50_Q7VSG1 Cluster: Gluconate 5-dehydrogenase; n=11; Proteo... 37 0.58 UniRef50_Q39GB0 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.58 UniRef50_Q676G3 Cluster: Probable short-chain dehydrogenase; n=1... 37 0.58 UniRef50_Q24Z94 Cluster: Putative uncharacterized protein; n=1; ... 37 0.58 UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 37 0.58 UniRef50_Q1IPD7 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.58 UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 37 0.58 UniRef50_A3PW05 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.58 UniRef50_A3JMX6 Cluster: YdfG; n=4; Rhodobacterales|Rep: YdfG - ... 37 0.58 UniRef50_A0QN49 Cluster: NAD dependent epimerase/dehydratase fam... 37 0.58 UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 36 0.77 UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 36 0.77 UniRef50_Q57A51 Cluster: Oxidoreductase, short-chain dehydrogena... 36 0.77 UniRef50_Q4K9W5 Cluster: Oxidoreductase, short-chain dehydrogena... 36 0.77 UniRef50_Q396I4 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.77 UniRef50_Q2RYU4 Cluster: Putative oxidoreductase; n=1; Salinibac... 36 0.77 UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.77 UniRef50_Q12HC0 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.77 UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena... 36 0.77 UniRef50_A7HRS7 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.77 UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.77 UniRef50_A6CLR0 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 36 0.77 UniRef50_A0ZL93 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.77 UniRef50_Q5CAF5 Cluster: Neomenthol dehydrogenase; n=5; core eud... 36 0.77 UniRef50_A4VDN4 Cluster: Putative uncharacterized protein; n=2; ... 36 0.77 UniRef50_Q6C392 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 36 0.77 UniRef50_A2RBM4 Cluster: Contig An19c0010, complete genome; n=6;... 36 0.77 UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 36 1.0 UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 36 1.0 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 36 1.0 UniRef50_Q5ZRL8 Cluster: Pteridine reductase 1; n=4; Legionella ... 36 1.0 UniRef50_Q39N07 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.0 UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: A... 36 1.0 UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 36 1.0 UniRef50_Q1GM72 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.0 UniRef50_Q1FGW1 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.0 UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.0 UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 36 1.0 UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.0 UniRef50_A3CQN6 Cluster: Dehydrogenase, eukaryotic-like, putativ... 36 1.0 UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.0 UniRef50_A0YFJ5 Cluster: Possible 3-oxoacyl-acyl carrier protein... 36 1.0 UniRef50_Q1ZXP6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0 UniRef50_Q5UY99 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 36 1.0 UniRef50_UPI0000E4927A Cluster: PREDICTED: similar to retinol de... 36 1.3 UniRef50_UPI00006CA45C Cluster: oxidoreductase, short chain dehy... 36 1.3 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 36 1.3 UniRef50_Q98K50 Cluster: Mlr1637 protein; n=2; Proteobacteria|Re... 36 1.3 UniRef50_Q89ML0 Cluster: Blr4183 protein; n=16; Bacteria|Rep: Bl... 36 1.3 UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 36 1.3 UniRef50_Q39MZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.3 UniRef50_Q2LXS6 Cluster: 3-oxoacyl-reductase; n=2; Proteobacteri... 36 1.3 UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.3 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 36 1.3 UniRef50_Q1N366 Cluster: Enoyl-(Acyl carrier protein) reductase;... 36 1.3 UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.3 UniRef50_Q124X5 Cluster: Male sterility-like; n=9; Proteobacteri... 36 1.3 UniRef50_Q0LKA9 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.3 UniRef50_A7K011 Cluster: Oxidoreductase, short chain dehydrogena... 36 1.3 UniRef50_A6PRL3 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.3 UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/redu... 36 1.3 UniRef50_A3VA26 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.3 UniRef50_A3UES7 Cluster: Probable short-chain dehydrogenase; n=1... 36 1.3 UniRef50_A3SFH7 Cluster: Oxidoreductase, short-chain dehydrogena... 36 1.3 UniRef50_Q61YR4 Cluster: Putative uncharacterized protein CBG034... 36 1.3 UniRef50_Q5BAR1 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3 UniRef50_A2R758 Cluster: Putative sequencing error; n=1; Aspergi... 36 1.3 UniRef50_Q9HRV8 Cluster: Oxidoreductase homolog; n=1; Halobacter... 36 1.3 UniRef50_O05730 Cluster: Probable short-chain type dehydrogenase... 36 1.3 UniRef50_UPI0000499488 Cluster: hypothetical protein 137.t00011;... 35 1.8 UniRef50_Q8U9R1 Cluster: Short-chain dehydrogenase; n=3; Rhizobi... 35 1.8 UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu... 35 1.8 UniRef50_Q6F7B8 Cluster: Fatty acyl-CoA reductase; n=6; Moraxell... 35 1.8 UniRef50_Q485Z0 Cluster: Oxidoreductase, short-chain dehydrogena... 35 1.8 UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_Q1AY52 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_Q11VS1 Cluster: Sensor protein; n=1; Cytophaga hutchins... 35 1.8 UniRef50_Q0RK88 Cluster: Putative short chain dehydrogenase; n=1... 35 1.8 UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_A6EHZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_A4XJ72 Cluster: Integral membrane sensor signal transdu... 35 1.8 UniRef50_A3JIH3 Cluster: Acetoacetyl-CoA reductase; n=3; Gammapr... 35 1.8 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_A1K6U9 Cluster: Short-chain dehydrogenase family protei... 35 1.8 UniRef50_A0JXQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.8 UniRef50_A6NNS2 Cluster: Uncharacterized protein DHRS7C; n=25; E... 35 1.8 UniRef50_P50199 Cluster: Gluconate 5-dehydrogenase; n=35; Bacter... 35 1.8 UniRef50_UPI000023E41C Cluster: hypothetical protein FG03853.1; ... 35 2.4 UniRef50_Q89QU6 Cluster: Bll3028 protein; n=6; Proteobacteria|Re... 35 2.4 UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 35 2.4 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.4 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.4 UniRef50_Q1RS55 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 35 2.4 UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.4 UniRef50_Q0R4G2 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 35 2.4 UniRef50_A7DM41 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.4 UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.4 UniRef50_A3M278 Cluster: Dehydrogenase/reductase; n=1; Acinetoba... 35 2.4 UniRef50_A3JX84 Cluster: Short chain dehydrogenase; n=5; Alphapr... 35 2.4 UniRef50_A0Z410 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 35 2.4 UniRef50_A1CD13 Cluster: Oxidoreductase, short-chain dehydrogena... 35 2.4 UniRef50_A1CD02 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4 UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4; ... 35 2.4 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.4 UniRef50_P14697 Cluster: Acetoacetyl-CoA reductase; n=25; Bacter... 35 2.4 UniRef50_P50204 Cluster: Acetoacetyl-CoA reductase; n=67; Proteo... 35 2.4 UniRef50_Q9HT49 Cluster: Probable short-chain dehydrogenase; n=5... 34 3.1 UniRef50_Q89V28 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 34 3.1 UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 34 3.1 UniRef50_Q7U927 Cluster: Putative short-chain dehydrogenase fami... 34 3.1 UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_Q937T4 Cluster: DcaC; n=2; Acinetobacter sp. ADP1|Rep: ... 34 3.1 UniRef50_Q1ASB7 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_Q15W58 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_Q11BF7 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_A6VSM3 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_A6EIS2 Cluster: Probable dehydrogenase/reductase; n=1; ... 34 3.1 UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 34 3.1 UniRef50_A5FF05 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_A5FER5 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_A1ETD9 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1 UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ... 34 3.1 UniRef50_Q54WM6 Cluster: Putative uncharacterized protein; n=2; ... 34 3.1 UniRef50_Q5KMG2 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1 UniRef50_Q5K7F7 Cluster: Putative uncharacterized protein; n=4; ... 34 3.1 UniRef50_Q0UDK9 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1 UniRef50_Q8TP33 Cluster: Short chain dehydrogenase; n=1; Methano... 34 3.1 UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 34 3.1 UniRef50_A7I5B4 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_A7D324 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.1 UniRef50_Q5UQ89 Cluster: Putative BTB/POZ domain-containing prot... 34 3.1 UniRef50_Q9BPW9 Cluster: Dehydrogenase/reductase SDR family memb... 34 3.1 UniRef50_UPI0000E46C37 Cluster: PREDICTED: hypothetical protein;... 34 4.1 UniRef50_UPI0000587AAC Cluster: PREDICTED: hypothetical protein;... 34 4.1 UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 34 4.1 UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reduc... 34 4.1 UniRef50_Q4UJP9 Cluster: Oxidoreductase; n=6; Rickettsia|Rep: Ox... 34 4.1 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 34 4.1 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.1 UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.1 UniRef50_A6L8V5 Cluster: Putative short-chain dehydrogenase; n=1... 34 4.1 UniRef50_A6ERE9 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.1 UniRef50_A4XEW8 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.1 UniRef50_A3IAI0 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.1 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.1 UniRef50_Q4WJE3 Cluster: Short-chain dehydrogenase/reductase fam... 34 4.1 UniRef50_Q4PDD2 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1 UniRef50_Q0U5K1 Cluster: Putative uncharacterized protein; n=1; ... 34 4.1 UniRef50_Q9HKZ9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 34 4.1 UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 34 4.1 UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 33 5.4 UniRef50_Q97RW1 Cluster: Oxidoreductase, short chain dehydrogena... 33 5.4 UniRef50_Q8A945 Cluster: Putative oxidoreductase; n=3; Bacteroid... 33 5.4 UniRef50_Q2IK95 Cluster: Short-chain dehydrogenase/reductase SDR... 33 5.4 UniRef50_Q7P820 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 33 5.4 UniRef50_Q0RV77 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 33 5.4 UniRef50_Q0JZY8 Cluster: 3-Oxoacyl-[acyl-carrier-protein] reduct... 33 5.4 UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR... 33 5.4 UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 33 5.4 UniRef50_A4CMC6 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4 UniRef50_A1ZFB1 Cluster: Peroxisomal trans-2-enoyl-CoA reductase... 33 5.4 UniRef50_A1W2D9 Cluster: Short-chain dehydrogenase/reductase SDR... 33 5.4 UniRef50_A1T2P6 Cluster: Short-chain dehydrogenase/reductase SDR... 33 5.4 UniRef50_A1IB60 Cluster: Short-chain alcohol dehydrogenase-like ... 33 5.4 UniRef50_Q941A7 Cluster: AT4g20760/F21C20_110; n=11; Magnoliophy... 33 5.4 UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ... 33 5.4 UniRef50_Q9W590 Cluster: CG14788-PA; n=8; Coelomata|Rep: CG14788... 33 5.4 UniRef50_Q38D48 Cluster: Short-chain dehydrogenase, putative; n=... 33 5.4 UniRef50_Q24E38 Cluster: Leucine Rich Repeat family protein; n=1... 33 5.4 UniRef50_Q16VA5 Cluster: Short-chain dehydrogenase; n=2; Aedes a... 33 5.4 UniRef50_Q0UEE2 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4 UniRef50_Q9KWN1 Cluster: Serine 3-dehydrogenase; n=156; Bacteria... 33 5.4 UniRef50_Q01718 Cluster: Adrenocorticotropic hormone receptor; n... 33 5.4 UniRef50_Q9A326 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 33 7.2 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 33 7.2 UniRef50_Q8YVU0 Cluster: All1884 protein; n=3; Bacteria|Rep: All... 33 7.2 UniRef50_Q8NR56 Cluster: Predicted rRNA or tRNA methylase; n=5; ... 33 7.2 UniRef50_Q8A936 Cluster: Sensor protein; n=4; Bacteria|Rep: Sens... 33 7.2 UniRef50_Q82IY9 Cluster: 1-deoxy-11beta-hydroxypentalenic acid d... 33 7.2 UniRef50_Q3BTU5 Cluster: Short chain dehydrogenase; n=1; Xanthom... 33 7.2 UniRef50_Q26CE0 Cluster: Putative oxidoreductase-dehydrogenase; ... 33 7.2 UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena... 33 7.2 UniRef50_Q0SUR2 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_Q03U43 Cluster: Short-chain alcohol dehydrogenase; n=4;... 33 7.2 UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_A5Z3D5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_A4XR20 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2 UniRef50_A3UVP3 Cluster: Baseplate J-like protein; n=1; Vibrio s... 33 7.2 UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 33 7.2 UniRef50_A1ULI4 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_A1IDP9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 33 7.2 UniRef50_A0YGB7 Cluster: Probable short-chain dehydrogenase; n=1... 33 7.2 UniRef50_A0UVI1 Cluster: AMP-dependent synthetase and ligase; n=... 33 7.2 UniRef50_A0JRM0 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_A0GXH7 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_A0G471 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.2 UniRef50_Q8IAN9 Cluster: Putative uncharacterized protein MAL8P1... 33 7.2 UniRef50_Q16FV1 Cluster: Short-chain dehydrogenase; n=4; Culicid... 33 7.2 UniRef50_A2GFH7 Cluster: Surface antigen BspA-like; n=1; Trichom... 33 7.2 UniRef50_Q2U788 Cluster: Dehydrogenases with different specifici... 33 7.2 UniRef50_A4QXZ6 Cluster: Putative uncharacterized protein; n=3; ... 33 7.2 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 33 7.2 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 33 7.2 UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai... 33 9.5 UniRef50_Q8XAM8 Cluster: Putative fatty acyl chain reductase; n=... 33 9.5 UniRef50_Q740T8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.5 UniRef50_Q2JKD0 Cluster: Oxidoreductase, short chain dehydrogena... 33 9.5 UniRef50_Q2ILQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 33 9.5 UniRef50_Q7D071 Cluster: AGR_C_1817p; n=6; Alphaproteobacteria|R... 33 9.5 UniRef50_Q4C7M6 Cluster: Short-chain dehydrogenase/reductase SDR... 33 9.5 UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida... 33 9.5 UniRef50_Q1ITJ9 Cluster: Short-chain dehydrogenase/reductase SDR... 33 9.5 UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR... 33 9.5 UniRef50_Q12GM0 Cluster: Short-chain dehydrogenase/reductase SDR... 33 9.5 UniRef50_Q04HM4 Cluster: D-alanine transfer protein, short-chain... 33 9.5 UniRef50_A6CL44 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 33 9.5 UniRef50_A6AJL0 Cluster: Short chain dehydrogenase; n=2; Vibrio ... 33 9.5 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 33 9.5 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 33 9.5 UniRef50_A3HTP5 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 33 9.5 >UniRef50_UPI0000E498BD Cluster: PREDICTED: similar to Carbonyl reductase 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Carbonyl reductase 1 - Strongylocentrotus purpuratus Length = 291 Score = 118 bits (285), Expect = 1e-25 Identities = 69/210 (32%), Positives = 114/210 (54%), Gaps = 2/210 (0%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKL--NGTVYFTASDEEEGLKATENFNNIGLYPKFL 226 M QKVA++ +GLA+V+AL + NG VY TA +EE G++A E GL P+F Sbjct: 1 MPQKVAVVTGSNTGIGLAMVRALCKHFGENGVVYLTARNEERGMQAVEVLKKEGLNPRFH 60 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 L + D +++K+ D I+ HG DILINN L + D P YE+A + ++ Y +L++ Sbjct: 61 LLDVNDVTSMEKLRDDIKTEHGGVDILINNAGILSKF-DIPMYEQAVEMTNTNYHGVLLM 119 Query: 407 EQYLFPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLEN 586 P+++D GRV+ + + G + + ++ TVE++ L + EY+++ + Sbjct: 120 TNTFLPIIRDGGRVVQLASLMGARTFYDISEELQHRFRDVSTVEEVTGL-MNEYIKATKE 178 Query: 587 GKFDKKWFSDDGKIAEYKISMVARTALTFV 676 G F K +++ Y IS + ALT V Sbjct: 179 GDFKTKGWAE----LAYGISKIGVAALTKV 204 >UniRef50_O97166 Cluster: 3-alpha-hydroxysteroid dehydrogenase-like protein; n=1; Branchiostoma floridae|Rep: 3-alpha-hydroxysteroid dehydrogenase-like protein - Branchiostoma floridae (Florida lancelet) (Amphioxus) Length = 273 Score = 100 bits (240), Expect = 3e-20 Identities = 58/208 (27%), Positives = 111/208 (53%), Gaps = 1/208 (0%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 +VA++ +GLAIVK L ++ +GTVY TA DE +G +A + N G P+F + Sbjct: 3 RVAVVTGANKGIGLAIVKGLCKQFDGTVYLTARDESKGQEAVKELNEQGCQPRFHQLDVL 62 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDL-KQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 ++ + ++ H D+L+NN + P E+ + + + LL + + L Sbjct: 63 SLDSIHRFKQHLEKEHQGLDVLVNNAGVMYGGSNPTPLVEQVEVTMGINFFGLLNLTKAL 122 Query: 419 FPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKFD 598 PLLK R++NV++ G LS + ++ +T + LT E++ + +E+++R +++G + Sbjct: 123 TPLLKPHARIVNVSSGLGDLSYVTPER-RQTFQSKQLTEEELVQM-MEQFVRDVKSGVHE 180 Query: 599 KKWFSDDGKIAEYKISMVARTALTFVWQ 682 +K + + Y++S + TAL+ V Q Sbjct: 181 EKGWKMEP--LGYRVSKMGATALSMVQQ 206 >UniRef50_A7RGK5 Cluster: Predicted protein; n=4; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 93.9 bits (223), Expect = 4e-18 Identities = 64/206 (31%), Positives = 103/206 (50%), Gaps = 1/206 (0%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 +VA++ +G AIV+ L ++ +GTV TA +E G +A + GL P F IT Sbjct: 7 RVAVVTGSNKGIGFAIVRGLCKQFSGTVILTARNENLGKEAVDKLKEEGLNPVFHQLDIT 66 Query: 242 DKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 + ++ K+ D + + D+LINN K P E+A+ + + L + L Sbjct: 67 SQESINKLRDYLSSTYKGLDLLINNAGIAYKGASIAPFSEQAEVTARTNFTGTLNICDTL 126 Query: 419 FPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKFD 598 FPLL+ RV+NV + G L I ++ T+P LT + L VEE++ ++ G Sbjct: 127 FPLLRPHARVVNVASLAGLLKIIPSEAIKAKFTSPSLTQSGLVGL-VEEFISDVKAGVHK 185 Query: 599 KKWFSDDGKIAEYKISMVARTALTFV 676 +K +S+ + Y +S VA ALT V Sbjct: 186 EKGWSN----SAYGMSKVAVIALTKV 207 >UniRef50_A7SF98 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 263 Score = 89.0 bits (211), Expect = 1e-16 Identities = 55/205 (26%), Positives = 107/205 (52%), Gaps = 4/205 (1%) Frame = +2 Query: 74 IINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDKPA 253 + G +G +V+ L ++ +G + TA +E+G A + N +G ++ +T + Sbjct: 1 VTGGNRGIGYCVVQQLVQQFDGNIILTARSDEQGEAACRSLN-VGGRVEYHKLDVTSNDS 59 Query: 254 LKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY-EEAKNVIDSKYKSLLIVEQYLFPLL 430 + ++ +Q +G DIL+NN LK+ +Y +A++ + + + +L V ++PLL Sbjct: 60 IHELTLHVQEKYGGLDILVNNAGILKKESSGTSYARKAEDCVKTNFFGMLDVYNSMYPLL 119 Query: 431 KDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKF-DKKW 607 K+ R++NV++ G L I + +P LTV Q NL ++ Y+R ++NG+ + W Sbjct: 120 KEQARIVNVSSTMGSL-KIVHPSLALQFISPKLTVRQCVNL-MQAYIRDVKNGRVAENGW 177 Query: 608 FSDDGKI--AEYKISMVARTALTFV 676 + K+ Y +S + TALT + Sbjct: 178 PVEKLKVHNPAYSVSKLGVTALTSI 202 >UniRef50_UPI0000E494E7 Cluster: PREDICTED: similar to Carbonyl reductase 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Carbonyl reductase 1 - Strongylocentrotus purpuratus Length = 417 Score = 86.2 bits (204), Expect = 7e-16 Identities = 61/229 (26%), Positives = 106/229 (46%), Gaps = 5/229 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKL--NGTVYFTASDEEEGLKATENFNNIGLYPKF 223 ++SQKV G +GL IV+AL +G VY TA + G A E GL PKF Sbjct: 12 SLSQKVTGANKG---IGLEIVRALCRHFGQDGVVYLTARNIGRGRAAVELLQKEGLDPKF 68 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 L +TD+ ++ K D ++ HG D+L+NN + FP Y ++ V+ + + +L Sbjct: 69 HLLDVTDQSSIDKFRDHLEKEHGGIDVLVNNA-GIGTPNHFPLYGKSLWVMKTNFFGVLA 127 Query: 404 VEQYLFPLLKDSGRVINVTNAYGHL--SNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRS 577 + Q L PL++ GR+++V G++ N ND + +D + E+L+ Sbjct: 128 ISQSLIPLVRSGGRIVHVAGTTGYMVFRNQFNDDIRNRFRKAKDEQDVVD--LINEFLKF 185 Query: 578 LENGKF-DKKWFSDDGKIAEYKISMVARTALTFVWQNXXXXXXXLR*CC 721 + G + W + IA+ + +++ + Q+ + CC Sbjct: 186 CKEGTIAENGWPDEADGIAKVGVIALSKIQAAKLSQDKSRRGILINACC 234 >UniRef50_UPI0000E47A47 Cluster: PREDICTED: similar to serum lectin P35; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to serum lectin P35 - Strongylocentrotus purpuratus Length = 740 Score = 82.2 bits (194), Expect = 1e-14 Identities = 44/134 (32%), Positives = 75/134 (55%), Gaps = 2/134 (1%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKL--NGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 SQ + ++ LGLAIV++L ++L +G VY TA +E GL+A + GL PKF + Sbjct: 574 SQGATAVTGSSSGLGLAIVRSLCKRLGDDGIVYLTARNEGRGLEAVDVLKKEGLGPKFHI 633 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 + D+ +++ + D I HG DIL+NN + +D P +A+ I + Y ++ V Sbjct: 634 LDVNDQDSIETLRDDIAAQHGGLDILVNNAGIIFN-DDTPKAIQAEKTIQTNYFAVRNVT 692 Query: 410 QYLFPLLKDSGRVI 451 L P+++D G ++ Sbjct: 693 NALLPIIRDGGSLV 706 >UniRef50_UPI0000E46681 Cluster: PREDICTED: similar to carbonyl reductase; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to carbonyl reductase - Strongylocentrotus purpuratus Length = 312 Score = 82.2 bits (194), Expect = 1e-14 Identities = 51/163 (31%), Positives = 84/163 (51%), Gaps = 21/163 (12%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKL--NGTVYFTASDEEEGLKATENFNNIGLYPKFL 226 MS +VA++ +GL IV+AL +G VY TA +E GL A E GL PKF Sbjct: 1 MSVRVAVVTGANKGIGLEIVRALCRHFGQDGVVYLTARNEGRGLAAIELLQKEGLDPKFH 60 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN-------------------TEDLKQCEDFP 349 L +TD+ +++KI + ++ HG D+L+NN T + Q E+ Sbjct: 61 LLDVTDQSSIEKIRNHLEKEHGGIDVLVNNAGIDTPDGEIYAGLDLVIFTNLVLQKENIS 120 Query: 350 TYEEAKNVIDSKYKSLLIVEQYLFPLLKDSGRVINVTNAYGHL 478 YE+ V+++ + L+ V Q + PL++ R++NV + G++ Sbjct: 121 FYEKRFRVMEANFFGLISVCQSIIPLVRSGRRIVNVASTTGYI 163 >UniRef50_P16152 Cluster: Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 1) (Prostaglandin-E(2) 9-reductase); n=74; Euteleostomi|Rep: Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 1) (Prostaglandin-E(2) 9-reductase) - Homo sapiens (Human) Length = 277 Score = 73.3 bits (172), Expect = 5e-12 Identities = 52/222 (23%), Positives = 101/222 (45%), Gaps = 3/222 (1%) Frame = +2 Query: 65 VAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITD 244 VA++ G +GLAIV+ L +G V TA D G A + GL P+F I D Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66 Query: 245 KPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 +++ + D ++ +G D+L+NN K + P + +A+ + + + V L Sbjct: 67 LQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELL 126 Query: 422 PLLKDSGRVINVTNAYG-HLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKFD 598 PL+K GRV+NV++ + + + + +T E++ L + +++ + G Sbjct: 127 PLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGL-MNKFVEDTKKGVHQ 185 Query: 599 KK-WFSDDGKIAEYKISMVARTALTFVWQNXXXXXXXLR*CC 721 K+ W S + + +++++R + + L CC Sbjct: 186 KEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACC 227 >UniRef50_Q5DEH8 Cluster: SJCHGC00683 protein; n=2; Schistosoma|Rep: SJCHGC00683 protein - Schistosoma japonicum (Blood fluke) Length = 277 Score = 66.9 bits (156), Expect = 5e-10 Identities = 55/215 (25%), Positives = 104/215 (48%), Gaps = 9/215 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGT----VYFTASDEEEGLKATENFNNIGLYPKFLL 229 K+A + +G IV+ L+E + +Y TA + E GL+A + + GL KF Sbjct: 2 KLAFVTGSNKGIGYNIVEKLAEFYGESSEWDIYLTARNVELGLEAVKKLSGKGLDVKFHQ 61 Query: 230 AQITDKPALKKIADTIQMNH-GSFDILINNTEDLKQCED-FPTYEEAKNVIDSKYKSLLI 403 ITD+ + K ++ N+ ++ +NN + E P E+A+ I++ + S + Sbjct: 62 LDITDRDSRKAFLTFVKTNYPNGINVAVNNAGIAYKVESATPFGEQARVTINTNFTSTID 121 Query: 404 VEQYLFPLLKDSGRVINVTNAYG--HLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRS 577 + PLL + RV+NV+++ L N++ND + K P +E + E++++ Sbjct: 122 FTEEFIPLLAEHARVVNVSSSLSLTSLKNLRNDLYEK-FVGPMNLIEL--RKLMSEFVKA 178 Query: 578 LENGKFDKK-WFSDDGKIAEYKISMVARTALTFVW 679 E+G +K W S Y++S + T +F++ Sbjct: 179 AEDGTCSEKGWPS-----TAYEVSKLGLTKASFIF 208 >UniRef50_Q501A2 Cluster: At5g61830; n=8; Magnoliophyta|Rep: At5g61830 - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 65.7 bits (153), Expect = 1e-09 Identities = 51/214 (23%), Positives = 104/214 (48%), Gaps = 10/214 (4%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNG-TVYFTASDEEEGLKATENFNNI--GLYPKFLL 229 + VA++ +G I + L+ ++G TV TA + GL+A ++ + GL F Sbjct: 36 ENVAVVTGSNRGIGFEIARQLA--VHGLTVVLTARNVNAGLEAVKSLRHQEEGLKVYFHQ 93 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +TD ++++ ++ G DIL+NN T E A+ VI + Y+ + Sbjct: 94 LDVTDSSSIREFGCWLKQTFGGLDILVNNAGVNYNLGSDNTVEFAETVISTNYQGTKNMT 153 Query: 410 QYLFPLLKDS---GRVINVTNAYGHL----SNIKNDKWIKTLTAPDLTVEQIDNLFVEEY 568 + + PL++ S RV+NV++ G + + + N + L++PDL E++ + V ++ Sbjct: 154 KAMIPLMRPSPHGARVVNVSSRLGRVNGRRNRLANVELRDQLSSPDLLTEELIDRTVSKF 213 Query: 569 LRSLENGKFDKKWFSDDGKIAEYKISMVARTALT 670 + +++G ++ + +Y +S +A A T Sbjct: 214 INQVKDGTWESGGWPQ--TFTDYSMSKLAVNAYT 245 >UniRef50_UPI000155BDDB Cluster: PREDICTED: similar to NADP+ dependent prostaglandin dehydrogenase, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to NADP+ dependent prostaglandin dehydrogenase, partial - Ornithorhynchus anatinus Length = 134 Score = 64.5 bits (150), Expect = 3e-09 Identities = 31/89 (34%), Positives = 50/89 (56%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++S++VA++ G +GLAIV+AL + +GTV TA D +G + GL P F Sbjct: 40 SVSRRVALVTGGNRGIGLAIVRALGRRFSGTVILTARDPGQGQAVVQVLKEEGLSPLFHQ 99 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 ITD +++ + D + G D+L+NN Sbjct: 100 LDITDPQSVRTLRDYLLDTFGGLDVLVNN 128 >UniRef50_A3WIM4 Cluster: Putative dehydrogenase; n=1; Idiomarina baltica OS145|Rep: Putative dehydrogenase - Idiomarina baltica OS145 Length = 239 Score = 62.1 bits (144), Expect = 1e-08 Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 5/152 (3%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNG-TVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 KV ++ G +G IVK L L+G TVY A + EEG E F GL +F+ + Sbjct: 3 KVFLVTGGNKGIGKEIVKQLG--LHGHTVYLGARNVEEGRNIAEAFEASGLDVRFVYIDL 60 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCE--DFPTYEEAKNVIDSKYKSLLIVEQ 412 TD + K+ AD I+ G D LINN + + + E + ++ Y ++V Q Sbjct: 61 TDVNSQKEAADHIKSKSGLLDGLINNAGMINDFDLASSVSLESLRETFETNYFGTVMVTQ 120 Query: 413 YLFPLLKDSGR--VINVTNAYGHLSNIKNDKW 502 + LL+ R ++NV+ G ++ + W Sbjct: 121 NMLSLLRAGERKVIVNVSTGLGSMAMHGDPSW 152 >UniRef50_Q6H7C9 Cluster: Short-chain dehydrogenase/reductase protein-like; n=3; Oryza sativa|Rep: Short-chain dehydrogenase/reductase protein-like - Oryza sativa subsp. japonica (Rice) Length = 315 Score = 61.7 bits (143), Expect = 2e-08 Identities = 68/238 (28%), Positives = 102/238 (42%), Gaps = 32/238 (13%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNG-TVYFTASDEEEGLKATENFNNIGLYPK-FLLA 232 ++VA++ G LGL I K L+ NG TV TA EE G A +GL F Sbjct: 13 KRVAVVTGGNKGLGLEICKQLAA--NGVTVVLTARSEERGAGAAAALRQLGLSEVLFHQF 70 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF---------------------- 346 +++ + +AD I+ G DIL+NN L DF Sbjct: 71 DVSEPSSAAGLADFIKHKFGKLDILVNNAGILGVTFDFGNLDLNKAIEGKSANETLEWLM 130 Query: 347 ----PTYEEAKNVIDSKYKSLLIVEQYLFPLLKDS--GRVINVTNAYGHLSNIKNDKWIK 508 T E A+ + Y Q L PLL+ S GR++ V++ +G LS +K + Sbjct: 131 QHTVETAENAEECLKINYHGNKKTIQALLPLLQSSPDGRIVTVSSVFGQLSFFSGEKLKE 190 Query: 509 TLT-APDLTVEQIDNLFVEEYLRSLENGKFDKK-WFSDDGKIAEYKISMVARTALTFV 676 L L+ E+ID L E ++R ++G+ + + W + A YK S + A T V Sbjct: 191 ELNDFSKLSEERIDEL-AELFVRDFKDGELESRGWPARADAFAAYKTSKALQHAYTRV 247 >UniRef50_A0BRV4 Cluster: Chromosome undetermined scaffold_123, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_123, whole genome shotgun sequence - Paramecium tetraurelia Length = 254 Score = 60.1 bits (139), Expect = 5e-08 Identities = 50/180 (27%), Positives = 83/180 (46%), Gaps = 3/180 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKAT--ENFNNIGLYPKF 223 M K ++I G N LGL + + L+EK + + DE E K +NF N+ + K Sbjct: 1 MEAKRIVLITGANRGLGLKLAEVLAEKYSLILTARKQDELEKTKQNLEKNFQNLEI--KT 58 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 L ++ K +++K+ D + H D+L+NN ++ + +ID + Sbjct: 59 HLLDVSSKESVRKLKDWLVSQHLKIDVLVNNA---------GVNQDPRKIIDINLIGTID 109 Query: 404 VEQYLFPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLE 583 V + L LKD G+VI +++ G L N D +K T E+I L E L++ E Sbjct: 110 VTEQLLSTLKDDGKVILISSILGKLENQPQD--LKETLLKKKTKEEIIQLSEEFILKNQE 167 >UniRef50_Q097P7 Cluster: Carbonyl reductase [NADPH] 1 (Nadph-dependent carbonylreductase 1) (20-beta-hydroxysteroid dehydrogenase) (Prostaglandin-e(2) 9- reductase); n=2; Stigmatella aurantiaca DW4/3-1|Rep: Carbonyl reductase [NADPH] 1 (Nadph-dependent carbonylreductase 1) (20-beta-hydroxysteroid dehydrogenase) (Prostaglandin-e(2) 9- reductase) - Stigmatella aurantiaca DW4/3-1 Length = 234 Score = 58.8 bits (136), Expect = 1e-07 Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 6/174 (3%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 ++A++ LGL + K L+ + GT V TA EE+G KA GL FL + Sbjct: 5 QIALVTGANRGLGLELCKQLAAR--GTRVLLTARSEEKGQKAARALAEQGLPVSFLWLDV 62 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTE---DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 T + +L + + I G DIL+NN DLK+ + + I++ L + Sbjct: 63 TSEQSLVQGVEYISREFGRLDILVNNAAVSLDLKRPGLEIGMDIVRTTIETNVYGPLRLT 122 Query: 410 QYLFPLLKDS--GRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEE 565 Q PL++ + GR++NV++ G S I K L+ L + +F +E Sbjct: 123 QLAVPLMRKNHYGRIVNVSSGLGSFSRITAGKLAYRLSKASLNT--MTKVFADE 174 >UniRef50_Q7NNW5 Cluster: Glr0293 protein; n=6; Bacteria|Rep: Glr0293 protein - Gloeobacter violaceus Length = 243 Score = 58.4 bits (135), Expect = 2e-07 Identities = 41/156 (26%), Positives = 74/156 (47%), Gaps = 6/156 (3%) Frame = +2 Query: 38 FGI*TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYP 217 FG M +K+A++ G +G + + L+ V T+ D E+G A E + GL Sbjct: 5 FGGTFMDKKLAVVTGGNRGIGFEVSRQLAN-FGHRVILTSRDPEQGKTAAEKLQSEGLDV 63 Query: 218 KFLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQ-CEDFPTYEEA-----KNVID 379 F +TD + + +A ++ G DIL+NN L+ D +A + + Sbjct: 64 LFHPLDVTDPASAEALAGFVRERFGRLDILVNNAGILQDGGADAARLLDADLDMLRTTFE 123 Query: 380 SKYKSLLIVEQYLFPLLKDSGRVINVTNAYGHLSNI 487 + ++V L PL++ GRV+NV++ G L+++ Sbjct: 124 TNTLGPVLVAHALVPLMQGRGRVVNVSSGAGQLADM 159 >UniRef50_A6CM25 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=6; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Bacillus sp. SG-1 Length = 245 Score = 58.4 bits (135), Expect = 2e-07 Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 3/153 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M KVAI+ G N +G AIVK ++ N TV EEEGL+ T N G F Sbjct: 1 MESKVAIVTGGANGIGKAIVKEFCKE-NYTVILVDKKEEEGLELTRELNESGNTVIFKKC 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIV 406 + + +K + + I+ DILINN + + ++F EE VI + S+ Sbjct: 60 DVGNYAEVKHLFNEIKETFQKVDILINNA-GISKFKNFWDMEEKDWNEVISTNLSSVFYF 118 Query: 407 EQYLFPLLKD-SGRVINVTNAYGHLSNIKNDKW 502 + L+KD G +IN+ + +S + + Sbjct: 119 SKEAALLMKDMGGCIINMASTRATMSEANTEAY 151 >UniRef50_UPI0000E476E0 Cluster: PREDICTED: similar to Carbonyl reductase 1, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Carbonyl reductase 1, partial - Strongylocentrotus purpuratus Length = 364 Score = 58.0 bits (134), Expect = 2e-07 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 4/126 (3%) Frame = +2 Query: 77 INGTNI-LGLAIVKALSEKLN--GTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 + G N +G IV+AL ++L G VY + DE G KA + GL P+ + I + Sbjct: 138 VTGANKGIGFGIVRALCKELGERGVVYLASRDEGRGEKAVQELKGEGLNPRCIQLDICNN 197 Query: 248 PALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLFP 424 + K+AD + +G DIL+NN K P +A +++ + L + + L P Sbjct: 198 DHISKVADYFRDTYGGLDILVNNAGIAFKAAATEPDSIQAPVTVETNVFATLRLCRALIP 257 Query: 425 LLKDSG 442 L++ G Sbjct: 258 LIRSHG 263 >UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family - Psychroflexus torquis ATCC 700755 Length = 245 Score = 58.0 bits (134), Expect = 2e-07 Identities = 48/151 (31%), Positives = 76/151 (50%), Gaps = 6/151 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVAI+ GT +GLAI AL E V + +D+ GL ++ G F + Sbjct: 8 ITDKVAIVTGGTRGIGLAIAHALGEAGAKLVVTSRTDKFGGL---DSLKEAGHDVSFFES 64 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLK--QCEDF--PTYEEAKNV-IDSKYKSL 397 ITDK +KI D HG DIL+NN + + E+F ++ N+ +DS ++ Sbjct: 65 DITDKSVPQKIIDYTLDKHGVIDILVNNAGVAQHGEMEEFNDELLDKIMNINVDSVFR-- 122 Query: 398 LIVEQYLFPLLKD-SGRVINVTNAYGHLSNI 487 + L P+ K SG ++N+ + G +SNI Sbjct: 123 -MCRSVLTPMKKQGSGVILNIGSISGLVSNI 152 >UniRef50_A4X6Z1 Cluster: Short-chain dehydrogenase/reductase SDR; n=8; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Salinispora tropica CNB-440 Length = 263 Score = 58.0 bits (134), Expect = 2e-07 Identities = 42/166 (25%), Positives = 76/166 (45%), Gaps = 5/166 (3%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 +K+A+I +G I + L E+ TV A DE G +A ++ G+ L + Sbjct: 25 EKIALITGANKGIGYEIARQLGER-GHTVLVGARDETRGRQAVDSLVAQGIVAVPLRLDV 83 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPT---YEEAKNVIDSKYKSLLIVE 409 TD ++ A I+ +G D+L+NN P+ ++ + V ++ ++ V Sbjct: 84 TDPASISAAAAEIEQRYGRLDVLVNNAGIAGAANGAPSTVRADDLRQVYETNVLGVVSVT 143 Query: 410 QYLFPLLKD--SGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQ 541 + PLL+ + RV+NV++ G L+ N +W L +L Q Sbjct: 144 NAVLPLLRRAVAARVVNVSSHLGSLT--LNSQWDSALAGVNLMAYQ 187 >UniRef50_Q01IF3 Cluster: H0306B06.2 protein; n=15; Magnoliophyta|Rep: H0306B06.2 protein - Oryza sativa (Rice) Length = 294 Score = 56.8 bits (131), Expect = 5e-07 Identities = 45/182 (24%), Positives = 85/182 (46%), Gaps = 5/182 (2%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 + VA++ +GLA+ L E TV TA D E G A GL+ F + Sbjct: 19 ETVAVVTGANRGIGLALAARLGEH-GITVVLTARDAERGEAAAAALRARGLHVVFHRLDV 77 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 D +++ A ++ G DIL+NN D + E A+ V+ + + ++ + L Sbjct: 78 ADPASVQAFAAWLRDAIGGLDILVNNAAVSFNEIDTNSVEHAETVLRTNFYGAKMLTEAL 137 Query: 419 FPLLKDS---GRVINVTNAYGHLSNIKNDKWIKTLTAPD--LTVEQIDNLFVEEYLRSLE 583 PL + S R++N+++ G L+ + +D +K L + LT +++ + +L ++ Sbjct: 138 LPLFRRSPATSRILNISSQLGLLNKV-SDPELKRLLQDEERLTEAEVEGM-ASRFLAQVK 195 Query: 584 NG 589 +G Sbjct: 196 DG 197 >UniRef50_A5FMQ3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 246 Score = 56.4 bits (130), Expect = 7e-07 Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 8/153 (5%) Frame = +2 Query: 68 AIIINGTN-ILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYP-KFLLAQIT 241 +++I G N +GL I K LS K VY + D E+G + + N G K + +T Sbjct: 3 SVLITGANRSIGLEITKQLS-KQGLFVYLGSRDLEKGNEIVKELNKDGFQNIKAIQIDVT 61 Query: 242 DKPALKKIADTIQMNHGSFDILINNT----EDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 + ++ ++ G DILINN Q + ++ KNV ++ + ++ V Sbjct: 62 NPDSILAAKKIVENEQGKLDILINNAGISGGQFPQTASDTSVKDIKNVFETNFFGVISVT 121 Query: 410 QYLFPLLK--DSGRVINVTNAYGHLSNIKNDKW 502 Q LLK DS R+ N+T+ G L+ + W Sbjct: 122 QAFLELLKKSDSPRISNITSGLGSLTLHSDASW 154 >UniRef50_Q9LQ75 Cluster: T1N6.22 protein; n=13; core eudicotyledons|Rep: T1N6.22 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 325 Score = 56.0 bits (129), Expect = 9e-07 Identities = 60/235 (25%), Positives = 106/235 (45%), Gaps = 30/235 (12%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNG-TVYFTASDEEEGLKATENFNNIGLYP----KFL 226 +VA++ +G I + L+ NG TV TA DE +GL A + + F Sbjct: 35 RVAVVTGSNKGIGFEICRQLAN--NGITVVLTARDENKGLAAVQKLKTENGFSDQAISFH 92 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN--------TEDLKQCE--------DF---- 346 +++ + +A ++ G DIL+NN D+ + + D Sbjct: 93 PLDVSNPDTIASLAAFVKTRFGKLDILVNNAGVGGANVNVDVLKAQIAEAGAPTDISKIM 152 Query: 347 -PTYEEAKNVIDSKYKSLLIVEQYLFPLLK--DSGRVINVTNAYGHLSNIKNDKWIKTL- 514 TYE + + + Y + + + + PLL+ DS R++++ + G L N+ N+ W K + Sbjct: 153 SDTYEIVEECVKTNYYGVKRMCEAMIPLLQSSDSPRIVSIASTMGKLENVSNE-WAKGVL 211 Query: 515 -TAPDLTVEQIDNLFVEEYLRSLENGKFDKKWFSDDGKIAEYKISMVARTALTFV 676 A +LT E+ID + + EYL+ + G K + ++ Y +S A ALT V Sbjct: 212 SDAENLTEEKIDEV-INEYLKDYKEGALQVKGWPT--VMSGYILSKAAVIALTRV 263 >UniRef50_Q233Z6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 285 Score = 55.2 bits (127), Expect = 2e-06 Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 16/224 (7%) Frame = +2 Query: 62 KVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNI-GLYPK----F 223 K ++I G+N LG +V+ + K N + + + L+ E F I YP F Sbjct: 5 KKVVLITGSNKGLGFGLVEDILSK-NSSQFRVIMTARDQLRGEEAFQKIKAKYPAEEVDF 63 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINN-----TEDL-KQCEDF-PTYEEAKNVIDS 382 L I D+ + I I +G DIL+NN T DL Q E + P+ E AK Sbjct: 64 HLLDIEDEQSRINIVKYIAEKYGKIDILVNNAAYLLTHDLFNQPEGYQPSVETAKRTFSI 123 Query: 383 KYKSLLIVEQYLFPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVE 562 + + Q + P L D G+++ +++ G +S + +V++I L E Sbjct: 124 NLFGTISMTQQIIPYLADDGKILQISSRAGQISRQPQQTQQILSNSEGFSVQKITEL-AE 182 Query: 563 EYLRSLEN--GKFDKKWFSDDGKIAEYKISMVAR-TALTFVWQN 685 ++ + EN D++W ++++ ++ R L+ + QN Sbjct: 183 DFYKQCENKIQPQDQRWSFSAYEVSKCLLNAFTRHVGLSLLKQN 226 >UniRef50_A7PQQ5 Cluster: Chromosome chr6 scaffold_25, whole genome shotgun sequence; n=15; cellular organisms|Rep: Chromosome chr6 scaffold_25, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 379 Score = 54.4 bits (125), Expect = 3e-06 Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 4/111 (3%) Frame = +2 Query: 350 TYEEAKNVIDSKYKSLLIVEQYLFP--LLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAP 523 TYE A+ + + Y V + LFP LL +SGR++NV++ G L + N++ L Sbjct: 209 TYELAEECVKTNYYGTKGVTEALFPCLLLSNSGRIVNVSSGLGSLKFVSNERVRMELNDV 268 Query: 524 D-LTVEQIDNLFVEEYLRSL-ENGKFDKKWFSDDGKIAEYKISMVARTALT 670 D L+VE++D + V E+L + EN DK W + + Y IS A A T Sbjct: 269 DVLSVERLDEI-VNEFLNDVKENTLHDKGW---PTQTSAYTISKAAMNAYT 315 Score = 39.1 bits (87), Expect = 0.11 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPK-FLL 229 + + A++ + +GL I + L+ NG V TA DE+ GL+A + L F Sbjct: 81 TMRYAVVTGASKGIGLEICRQLAS--NGVMVVLTARDEKRGLEAVAKLHESSLSNVVFHQ 138 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 + D ++ +A I +G DIL+NN Sbjct: 139 LDVMDANSITSLATFIVTRYGKLDILVNN 167 >UniRef50_Q140F5 Cluster: Putative short-chain dehydrogenase/oxidoreductase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain dehydrogenase/oxidoreductase - Burkholderia xenovorans (strain LB400) Length = 245 Score = 54.0 bits (124), Expect = 4e-06 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 5/145 (3%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 +K+A++ T LG V+ L+ V A D G GL + + + Sbjct: 7 KKIALVTGATRGLGFETVRQLAAS-GVRVLLGARDTHAGEAKAAELRAEGLDVRPIAIDL 65 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY---EEAKNVIDSKYKSLLIVE 409 + + A I G DIL+NN + + FP+ + ++VI+ + + +IV Sbjct: 66 NNAATFDQAAKEIDALFGRLDILVNNAGVMSDADGFPSVANPQAMRDVIEINFIATVIVT 125 Query: 410 QYLFPLLKDS--GRVINVTNAYGHL 478 Q + PLL+ S GR++NV++ G L Sbjct: 126 QNMLPLLRKSKHGRIVNVSSRVGSL 150 >UniRef50_Q97SL2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=55; root|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Streptococcus pneumoniae Length = 271 Score = 53.2 bits (122), Expect = 6e-06 Identities = 35/148 (23%), Positives = 72/148 (48%), Gaps = 5/148 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ K+A+I + +G AI K+ +E T+ F +++ K E + +G+ + Sbjct: 12 SLKGKIALITGASYGIGFAIAKSYAEA-GATIVFNDINQDLVNKGIEAYREVGIQAHGYV 70 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQ---CEDFPTYEEAKNVIDSKYKSLL 400 +TD+ ++ + I+ G DIL+NN +++ CE + + + VID + Sbjct: 71 CDVTDEDGIQAMVKQIEQEVGVIDILVNNAGIIRRVPMCE--MSAADFRKVIDIDLNAPF 128 Query: 401 IVEQYLFP--LLKDSGRVINVTNAYGHL 478 IV + + P + K G++IN+ + L Sbjct: 129 IVSKAVIPSMIKKGHGKIINICSMMSEL 156 >UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase; n=1; Pyrococcus abyssi|Rep: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase - Pyrococcus abyssi Length = 240 Score = 53.2 bits (122), Expect = 6e-06 Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 2/139 (1%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA+I + +G AI L+++ V S+EEE K E G+ + A ++ Sbjct: 6 KVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTEELCRQYGVETLLVKADVS 65 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCED--FPTYEEAKNVIDSKYKSLLIVEQY 415 ++ ++++ + G DILINN L + +D T EE VI K IV Q Sbjct: 66 NREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAFIVTQE 125 Query: 416 LFPLLKDSGRVINVTNAYG 472 + +K G+++N+ + G Sbjct: 126 VLRYMK-KGKIVNIASIAG 143 >UniRef50_Q08MV7 Cluster: D-beta-hydroxybutyrate dehydrogenase; n=5; Bacteria|Rep: D-beta-hydroxybutyrate dehydrogenase - Stigmatella aurantiaca DW4/3-1 Length = 394 Score = 52.8 bits (121), Expect = 8e-06 Identities = 38/144 (26%), Positives = 67/144 (46%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 MSQK A++ N +GLA+ +ALS + V DEE G A N F Sbjct: 142 MSQKCAVVTGAANGIGLAVAQALSAQ-GARVLMADLDEERGQAAARELPN----ALFQRT 196 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 I + + + + G DIL+NN + + EDFP + ++++ ++ Sbjct: 197 DIASREDCRTLVARAEREWGRLDILVNNAGLQHVSPVEDFPE-DRWEHLLRIMLVGPFLL 255 Query: 407 EQYLFPLL--KDSGRVINVTNAYG 472 +Y P++ + GR+IN+++ +G Sbjct: 256 TKYALPMMYARRWGRIINMSSLHG 279 >UniRef50_A1ZM53 Cluster: Short chain dehydrogenase; n=1; Microscilla marina ATCC 23134|Rep: Short chain dehydrogenase - Microscilla marina ATCC 23134 Length = 244 Score = 52.0 bits (119), Expect = 1e-05 Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 9/155 (5%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 +KVA I +G + L++K TV + ++ G +A+E + GL +FL I Sbjct: 2 KKVAFITGANKGIGFEASRQLAKK-GITVIMGSRSDQRGKQASEQLKSEGLDVEFLKLDI 60 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF-------PTYEEAKNVIDSKYKSL 397 T + + I +G DIL+NN + E + + E + + + L Sbjct: 61 TQPESFDEAKKYIDEKYGQLDILVNNAGIIHSEESWGENTTETVSLEALRQTFEVNFFGL 120 Query: 398 LIVEQYLFPLLKDS--GRVINVTNAYGHLSNIKND 496 + + Q L PL++ S G + NV++ G + N++ND Sbjct: 121 VALTQKLLPLIRKSKQGYITNVSSILGSV-NVQND 154 >UniRef50_A1FW82 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=8; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Stenotrophomonas maltophilia R551-3 Length = 283 Score = 52.0 bits (119), Expect = 1e-05 Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K+A++ T +G V+ L++ T+ E ++ GL + + +T Sbjct: 45 KIALVTGATRGIGAETVRQLAQAGVHTL-LAGRKRETAVEQALKLQAEGLPVEAIQLDVT 103 Query: 242 DKPALKKIADTIQMNHGSFDILINNT----EDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 D ++ + + ++ HG DIL+NN E+ Q + + K D+ +L+ V Sbjct: 104 DAASIAEAVEQVRQRHGRLDILVNNAGIMIENPAQAPSEQSLDTWKRTFDTNVYALVAVT 163 Query: 410 QYLFPLLKD--SGRVINVTNAYG 472 Q PL++ SGR++NV++ G Sbjct: 164 QAFLPLVRQAKSGRIVNVSSMLG 186 >UniRef50_Q00RH9 Cluster: OSIGBa0125M19.7 protein; n=12; Oryza sativa|Rep: OSIGBa0125M19.7 protein - Oryza sativa (Rice) Length = 1204 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPK-FL 226 T+ +VA++ G +GL + + L+ TV TA DE G++A E +GL F Sbjct: 969 TLRSRVAVVTGGNKGIGLEVCRQLAAD-GITVVLTARDETRGVEAAEKLRGMGLSCVIFH 1027 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN 316 ++TD ++ ++AD + G +IL+NN Sbjct: 1028 HLEVTDSSSVSRLADFLTTRFGKLEILVNN 1057 Score = 50.8 bits (116), Expect = 3e-05 Identities = 56/236 (23%), Positives = 102/236 (43%), Gaps = 33/236 (13%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPK---FLLA 232 ++A++ G +GL + L+ + V TA +E GL+A + G F Sbjct: 679 RIALVTGGNKGVGLETCRQLASR-GLRVVLTARNEARGLEAVDGIRRSGAADSDVVFHQL 737 Query: 233 QITDKPALKKIADTIQMNHGSFD---------------ILINNTEDLKQCEDFP------ 349 +TD ++ ++AD ++ G D +L+ +D + D Sbjct: 738 DVTDAASVARLADFVRDQFGRLDILINNAGISGVDRDPVLVAKVKDQIEGMDVDQRVEWM 797 Query: 350 ------TYEEAKNVIDSKYKSLLIVEQYLFPLL--KDSGRVINVTNAYGHLSNIKNDKWI 505 TY+EAK+ I + Y +V + L PLL SGR++NV++ +G L N ++ Sbjct: 798 RENSKETYDEAKSCITTNYYGAKLVTEALLPLLLLSSSGRIVNVSSGFGLLRNFNSEDLR 857 Query: 506 KTLTAPD-LTVEQIDNLFVEEYLRSLENGKFDKKWFSDDGKIAEYKISMVARTALT 670 K D LT ++++ L ++ +L + + + G A YK++ A A T Sbjct: 858 KEFDDIDSLTEKRLEEL-LDLFLDDFKVNLIEAHGWPTGGSSA-YKVAKAALNAYT 911 >UniRef50_Q8YZV3 Cluster: NADPH-dependent carbonyl reductase; n=5; Nostocaceae|Rep: NADPH-dependent carbonyl reductase - Anabaena sp. (strain PCC 7120) Length = 248 Score = 51.6 bits (118), Expect = 2e-05 Identities = 35/157 (22%), Positives = 78/157 (49%), Gaps = 8/157 (5%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 T +++A++ LG AI + L++ + V T+ +E +GL A + ++ GL + + Sbjct: 2 TEQKRIAVVTGSNRGLGYAISRKLAQ-IGIHVILTSRNEADGLAAKQQLSSEGLDADYCV 60 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN------TEDLKQCEDFPTYEEAKNVIDSKYK 391 +T+ +++K + + DIL+NN T+ + E + ++ Sbjct: 61 LDVTNDVSVQKFTKWLHETYSKVDILVNNAGINPTTKPEESSLLTVQLETMRFTWETNVL 120 Query: 392 SLLIVEQYLFPLL--KDSGRVINVTNAYGHLSNIKND 496 +++ + Q L PL+ ++ GR++N++ LS+I +D Sbjct: 121 AVVRITQALIPLMQAQNYGRIVNISTEMASLSSISDD 157 >UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrobacterium tumefaciens Length = 258 Score = 51.6 bits (118), Expect = 2e-05 Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 7/153 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEE---EGLKATENFNNIGLYPKFLLA 232 KVA+I GT +GLA A E +Y +A EE G T + ++ YP L Sbjct: 15 KVALITGGTRGIGLATAYAFGE-AGAKLYLSARREEYEDAGAILTAGY-DVTFYPADLKT 72 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIV 406 + +K++AD + G DILINN + D P + E ++VI + +++ Sbjct: 73 REAACALVKRVAD----DAGRLDILINNA-GIANGGDTPLFTEQQWRDVIATNVETVFWC 127 Query: 407 EQYLFPLLKDSGR--VINVTNAYGHLSNIKNDK 499 Q P++++ GR ++NV + G +SNI ++ Sbjct: 128 SQAAIPVMREGGRGAIVNVGSMSGIVSNIPQNQ 160 >UniRef50_Q1QYL7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Chromohalobacter salexigens DSM 3043|Rep: Short-chain dehydrogenase/reductase SDR - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 248 Score = 51.2 bits (117), Expect = 3e-05 Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 6/146 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M+ K+A+I GT +G A+ K L L V + D + KA + G + LL Sbjct: 4 MTSKIALITGGTKGIGYAVCKKLCS-LGVHVIMSGRDSSKLRKAVNSLKYDGHVIEGLLL 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT-----EDLKQCEDFPTYEEAKNVIDSKYKSL 397 ITD ++ + ++ +G DIL+NN + K + P E K + + ++ Sbjct: 63 DITDNESIHCARNYVRNKYGHLDILVNNAAIRVEQYGKAPSEQPLSEWLKTFNTNLFGTI 122 Query: 398 LIVEQYLFPLLKD-SGRVINVTNAYG 472 I L P+ SGR+INV++ G Sbjct: 123 SITNALLEPVKSSPSGRIINVSSLLG 148 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 51.2 bits (117), Expect = 3e-05 Identities = 39/150 (26%), Positives = 66/150 (44%), Gaps = 5/150 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + K A+I N +GLA K +++ V DE +G E G F Sbjct: 3 LKNKTAVITGSANGIGLAAAKKFAQE-GCKVIMADYDENKGAAEAEKLQEEGGDTVFYQV 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN---TEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 + ++ ++ +A + ++GS DILINN T D + ++ + V+D + Sbjct: 62 DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAK--MREDDFQRVLDVNLTGVFH 119 Query: 404 VEQYLFPLLKDS--GRVINVTNAYGHLSNI 487 Q L P L +S G++IN +A G N+ Sbjct: 120 CTQALLPALINSGKGKIINTASASGLYGNV 149 >UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=2; Bacteria|Rep: Predicted short chain dehydrogenase - Bacillus sp. B14905 Length = 251 Score = 51.2 bits (117), Expect = 3e-05 Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 2/142 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KV II G +G + KA++++ V + E G ++ I FL A Sbjct: 4 LDNKVVIITGGAGGIGSGMAKAMAKE-GAIVTIVDLNAEAGEAMEKDLQQISPKSMFLQA 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIVE 409 + ++ L KI DT+ +G D+L+NN KQ + T + + + + Sbjct: 63 NLMERDQLPKIIDTVVEKYGKLDVLVNNAHAAKQVTIEETTQADLDLSFGTGFYPTFYLM 122 Query: 410 QYLFPLLKDS-GRVINVTNAYG 472 Q P LK++ G +IN + G Sbjct: 123 QAALPHLKETQGNIINFASGAG 144 >UniRef50_Q89PU2 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=11; Proteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Bradyrhizobium japonicum Length = 252 Score = 50.4 bits (115), Expect = 4e-05 Identities = 34/139 (24%), Positives = 69/139 (49%), Gaps = 5/139 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KV ++ G + +G AIV+ +++ + V+F +EG + ++ GL F Sbjct: 8 LADKVVLVTGGASGIGAAIVRRFAQQKSNVVFFDIK-ADEGQRLARELSDQGLAAHFQRV 66 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDF-PTYEEAKNVIDSKYKSLLI 403 +TD AL+ + HG+ +IL+NN ++ E+ P Y + + ++ K++ Sbjct: 67 DLTDIAALRAGVAAARKAHGAINILVNNAAHDERHNTEEMTPEYWDDRIAVNLKHQ--FF 124 Query: 404 VEQYLFPLLK--DSGRVIN 454 Q + P +K +G +IN Sbjct: 125 AAQAVLPDMKAAKAGAIIN 143 >UniRef50_Q3A5G9 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: Short-chain alcohol dehydrogenase-like protein - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 266 Score = 50.4 bits (115), Expect = 4e-05 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 5/142 (3%) Frame = +2 Query: 62 KVAIIINGT-NILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 +VA++ GT N G V+AL+E TV+ T+ D + + ++ GL + L + Sbjct: 19 RVALVTGGTGNGYGSQAVRALAEA-GATVFITSRDPDRAQQTAKDLRESGLEVQGLGLDL 77 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPT--YEEAKNVIDSKYKSLLIVEQ 412 + ++ + DTI G DIL+NN E F T ++ V+ +++ + Sbjct: 78 ESEQSIAHVIDTIISKTGRLDILVNNACS-NHFESFETVSLKDWNQVLAVNITGTMLISR 136 Query: 413 YLFP--LLKDSGRVINVTNAYG 472 P L D G +IN+++ YG Sbjct: 137 ATAPHMLQNDGGVMINLSSIYG 158 >UniRef50_Q00RH3 Cluster: OSIGBa0125M19.13 protein; n=9; Oryza sativa|Rep: OSIGBa0125M19.13 protein - Oryza sativa (Rice) Length = 346 Score = 50.0 bits (114), Expect = 6e-05 Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 3/110 (2%) Frame = +2 Query: 350 TYEEAKNVIDSKYKSLLIVEQYLFPLLKDS--GRVINVTNAYGHLSNIKNDKWIKTLTAP 523 TY+ AKN + + Y V Q L PLL S G+++NV++A G L + N+ K L Sbjct: 175 TYDTAKNGVQTNYYGAKHVIQGLLPLLLSSSEGKIVNVSSALGLLRFLGNEDLRKELDDI 234 Query: 524 D-LTVEQIDNLFVEEYLRSLENGKFDKKWFSDDGKIAEYKISMVARTALT 670 D LT E++D + + +L+ E G+ + + A YK++ VA A T Sbjct: 235 DNLTEERLDEV-LASFLKDFEAGELEAHGWPMGS--AAYKVAKVAMNAYT 281 Score = 49.2 bits (112), Expect = 1e-04 Identities = 27/90 (30%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPK-FL 226 + S +VA++ G +GL + + L+ TV TA DE G++A E +GL F Sbjct: 10 SQSARVAVVTGGNKEIGLEVCRQLAAD-GITVVLTARDETRGVEAAERLRGMGLSSVVFH 68 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN 316 ++TD ++ ++AD ++ G DIL ++ Sbjct: 69 QLEVTDSSSVARLADFLKTRFGKLDILASS 98 >UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Moorella thermoacetica (strain ATCC 39073) Length = 253 Score = 49.6 bits (113), Expect = 8e-05 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 4/138 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K+ I + +G A+ + V + E+ L + +G + ++ Sbjct: 7 KIVWITGSSTGIGRAMALGFARNGANVVIHYNNSEKAALSLAQEIEQMGKKSLVVRGDVS 66 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIVEQY 415 DK + + I+ G D+LINN + + F +EA +I+ KS+ +V + Sbjct: 67 DKNQVDAMVSKIKERFGRIDVLINNAGSMIKRARFEEVDEALWDRIINVNLKSVFLVTKA 126 Query: 416 LFPLLK--DSGRVINVTN 463 +FP++K G++IN+T+ Sbjct: 127 VFPMMKAQGKGKIINITS 144 >UniRef50_A0M4X9 Cluster: Short-chain dehydrogenase/reductase family protein; n=2; Flavobacteriaceae|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 252 Score = 49.6 bits (113), Expect = 8e-05 Identities = 41/142 (28%), Positives = 67/142 (47%), Gaps = 4/142 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ K A+I G+ +G A V KL V FTA +E++ G L+A Sbjct: 4 LNDKKALITGGSKGIGKATVIEFL-KLGAEVLFTARNEKDIKLLETELKEEGHQVTGLVA 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 +KKI + I S DIL+NN KQ D+ + EE + V++ + + Sbjct: 63 DSAKPEDIKKIKNWIAERWNSLDILVNNAGINIRKQAIDY-SEEEFRKVLEINLVAPFEI 121 Query: 407 EQYLFPLLKDSGR--VINVTNA 466 + L+P LK SG+ +IN+ ++ Sbjct: 122 SRALYPFLKKSGKASIINIASS 143 >UniRef50_A0E1K9 Cluster: Chromosome undetermined scaffold_73, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_73, whole genome shotgun sequence - Paramecium tetraurelia Length = 276 Score = 49.6 bits (113), Expect = 8e-05 Identities = 44/203 (21%), Positives = 87/203 (42%), Gaps = 6/203 (2%) Frame = +2 Query: 71 IIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKA-TENFNNIGLYPK---FLLAQ 235 ++I G N +G I++ L +K + V E K+ TE L + Sbjct: 7 VVITGANKGIGFGILENLIQKQSYKVIMACRSLELAQKSRTELIEKYNLSQDRIDIIELD 66 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 I+ ++ K S DILINN + +DF +E + + + + + Sbjct: 67 ISSSDSIDKFIQEFTTRFHSADILINNAAVAVKTDDF-NFEIVQYTFKPNFYGTVELTEK 125 Query: 416 LFPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKF 595 PLL +G++I + + G+ +++D +K P++T E + L +E+ ++N + Sbjct: 126 FIPLLAQNGKIITIGSQVGNTKILESDDLVKRFKNPNITREDVFKL-ADEFQEHVKNNTY 184 Query: 596 DKK-WFSDDGKIAEYKISMVART 661 + W S I++ I+ +T Sbjct: 185 KQNGWPSWGYGISKLLINTYVKT 207 >UniRef50_UPI0000E47390 Cluster: PREDICTED: similar to retinol dehydrogenase 8 (all-trans), partial; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to retinol dehydrogenase 8 (all-trans), partial - Strongylocentrotus purpuratus Length = 216 Score = 49.2 bits (112), Expect = 1e-04 Identities = 41/148 (27%), Positives = 81/148 (54%), Gaps = 9/148 (6%) Frame = +2 Query: 65 VAIIINGTNI-LGLAIVKALSEKLNGT--VYFTASD--EEEGL-KATENFNNIGLYPKFL 226 + ++I+G + +GLA+ L++ + VY T + ++EGL KAT + + L+ + L Sbjct: 4 LVVLISGCSTGIGLALAARLAQDPDKKYLVYATMRNLAKKEGLEKATGDALDKTLFVRQL 63 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLI 403 + D+ +K I + I HG D+L+NN + + E+AK++ D+ Y + Sbjct: 64 DVTVDDQ--VKSIFEFIMGKHGRVDVLVNNAGFGFFGPLEAMSMEKAKSMFDTNYFGTVR 121 Query: 404 VEQYLFPLLK--DSGRVINVTNAYGHLS 481 + + P++K SGR++N+++ GHL+ Sbjct: 122 LIRAALPIMKKQKSGRIVNISSILGHLA 149 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 49.2 bits (112), Expect = 1e-04 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KVA+I G + +G A K + + + +EE+G + G F+ A Sbjct: 3 LQDKVAVITGGVSGIGAATAKLFASE-GAKLILVDMNEEKGASIEAELKSQGSEAIFIKA 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 +T++ +K I T G DIL NN +K E+ TY E + ++ + +V Sbjct: 62 DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEEL-TYAEWRKTVEVDLDGVFLV 120 Query: 407 EQYLFP--LLKDSGRVINVTNAYG 472 Q L SG ++N + YG Sbjct: 121 AQAAIKEFLKAGSGVIVNTASMYG 144 >UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Staphylococcus epidermidis|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 255 Score = 49.2 bits (112), Expect = 1e-04 Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 3/152 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVA++I G +G A+ +AL++ V AT G+ L Sbjct: 10 LTGKVAMVIGGATGIGKAMAEALAQAGANIVIADLQSNIGQETATTISTQSGVKTTSLKL 69 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 IT + +I D + +G DIL+NN ++ + +YEE I+ V Sbjct: 70 DITHSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLSLNGAFSVA 129 Query: 410 QYLFPLL--KDSGRVINVTNAYGHLSNIKNDK 499 Q + + K SG +INV++ G ++N D+ Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQ 161 >UniRef50_Q2W431 Cluster: Dehydrogenase with different specificities; n=2; Magnetospirillum|Rep: Dehydrogenase with different specificities - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 248 Score = 49.2 bits (112), Expect = 1e-04 Identities = 36/146 (24%), Positives = 67/146 (45%), Gaps = 4/146 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA+I G + +G VK+++E L V + E G KA G +F+ +T Sbjct: 6 KVALITGGASGIGYCTVKSMAE-LGADVLIADINVEAGEKAAAELTAKGFKAEFVRLDVT 64 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIVEQY 415 DK + ++ + + G DIL N + F ++A V+ + + + Sbjct: 65 DKANIARVKEHVVATRGRLDILC-NVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIELIRA 123 Query: 416 LFPLL--KDSGRVINVTNAYGHLSNI 487 FPL+ K +G+++NV + G + ++ Sbjct: 124 FFPLMIEKKTGKIVNVASDAGRVGSL 149 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 48.8 bits (111), Expect = 1e-04 Identities = 38/146 (26%), Positives = 61/146 (41%), Gaps = 3/146 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KVAI+ G +G AI + +E V DEE GL+ GL F+ Sbjct: 6 LKNKVAIVTGGGQGIGAAIAQLFAEN-GAKVVLAEIDEEAGLEREAMLRERGLDVTFIKT 64 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP-TYEEAKNVIDSKYKSLLIVE 409 + D+ ++K + +G DIL+NN + F T EE + VI I Sbjct: 65 DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124 Query: 410 QYLFP--LLKDSGRVINVTNAYGHLS 481 +Y + + G +IN+ + +S Sbjct: 125 RYAAEEMIKRGGGVIINIASTRALMS 150 >UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 257 Score = 48.0 bits (109), Expect = 2e-04 Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 8/153 (5%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ +KVA++ G +G AI +AL+ V +EE + E G F + Sbjct: 9 SLKRKVALVTGGGQGIGKAIAQALAAA-GAAVLIMDINEETARRTVEEIKEKGGEADFYV 67 Query: 230 AQITDKP----ALKKIADTIQMNHGSFDILINNTE--DLKQCEDFPTYEEAKNVIDSKYK 391 +T + A+KK D G DI +NN D + E++P E+ K VID Sbjct: 68 GDVTKEEDCFGAVKKALD----RWGKLDIGVNNAGIGDWCEAENYPV-EKWKKVIDVNLV 122 Query: 392 SLLIVEQYLFPLLKDS--GRVINVTNAYGHLSN 484 + + + F +K+ G++IN+ + GH+ N Sbjct: 123 GVFLSAKAEFHAMKERKYGKIINIASMSGHIVN 155 >UniRef50_Q6SFN3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; uncultured bacterium 580|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - uncultured bacterium 580 Length = 243 Score = 48.0 bits (109), Expect = 2e-04 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 8/149 (5%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 +KVA I +G K L+EK V + D +G KA E G+ + Sbjct: 2 EKVAFISGANRGIGFETSKKLAEK-GIKVILGSRDMVKGKKALEELAAQGIEADLIQYDA 60 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY------EEAKNVIDSKYKSLL 400 D A +K+ D I + DIL+NN L F T ++ K + S++ Sbjct: 61 ADLEAPQKVYDYILDKYNKLDILVNNAGVLLTGNLFVTNSTTVSDKDIKETFQTNLFSVI 120 Query: 401 IVEQYLFPLLK--DSGRVINVTNAYGHLS 481 + Q L PL+K ++GR++NV+ L+ Sbjct: 121 SLTQALLPLIKKSEAGRIVNVSTILSSLT 149 >UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Rep: Dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 254 Score = 48.0 bits (109), Expect = 2e-04 Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 4/150 (2%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQ 235 + KVA+I G+ +GLAI K E V + E KA E+ + G L Sbjct: 10 AHKVAVITGGSRSIGLAIAKRFYES-GMKVAILSVGEGSAKKAAESIDKSGTGALGLQCD 68 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTE--DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 ++D+ +++ + I G DIL+N+ D+ E+ T E V+ + + Sbjct: 69 VSDESSVELALEKINSLFGRIDILVNSAGILDMSSIEEMTT-EHWDKVLSTNLRGTFTTI 127 Query: 410 QYLFPLLKDS--GRVINVTNAYGHLSNIKN 493 Q L+ S R+IN+++ G + +N Sbjct: 128 QKSIKYLEKSKFPRIINISSNSGRMGGFEN 157 >UniRef50_A5B040 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 184 Score = 48.0 bits (109), Expect = 2e-04 Identities = 38/122 (31%), Positives = 61/122 (50%), Gaps = 3/122 (2%) Frame = +2 Query: 314 NTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLFPLLK--DSGRVINVTNAYGHLSNI 487 N + LK+ + TYE+A+ I + Y V Q L PLL+ S R++NV++ G L NI Sbjct: 53 NVDMLKEIKQ-RTYEKAEECIRTNYYGTQRVTQSLLPLLQLSPSARIVNVSSLRGQLKNI 111 Query: 488 KNDKWIKTL-TAPDLTVEQIDNLFVEEYLRSLENGKFDKKWFSDDGKIAEYKISMVARTA 664 N + L +LT E++D + ++ +LR + K + + YK+S A A Sbjct: 112 HNHQVKAELENVGELTEEKLDKI-LQRFLRDFKEDKLGANGWPVIA--SAYKVSKAAVNA 168 Query: 665 LT 670 T Sbjct: 169 YT 170 >UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 278 Score = 48.0 bits (109), Expect = 2e-04 Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 5/139 (3%) Frame = +2 Query: 71 IIING-TNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 I I+G T +GLAI + K V E A G+ P L + D+ Sbjct: 14 IFISGSTEGIGLAIAEEFG-KAGARVIVNGVRREVAENALNYLRGRGIEPILFLGDVADR 72 Query: 248 PALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 + K+ D I+ G D+L+NN E K ED+ YE + +I+ + ++ + L Sbjct: 73 GNVVKLRDLIEGECGRLDVLVNNASIEVDKPFEDY-DYETWRRLIEVNLDAYYMLARELL 131 Query: 422 PL-LKDSGRV-INVTNAYG 472 PL +K G+V IN+++ G Sbjct: 132 PLIIKGEGKVIINISSVQG 150 >UniRef50_Q6MHI6 Cluster: Short chain dehydrogenase; n=1; Bdellovibrio bacteriovorus|Rep: Short chain dehydrogenase - Bdellovibrio bacteriovorus Length = 236 Score = 47.6 bits (108), Expect = 3e-04 Identities = 39/178 (21%), Positives = 78/178 (43%), Gaps = 9/178 (5%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 +K+A++ LGLA+ +AL+++ V + ++ K GL + + Sbjct: 2 KKIAVVTGANRGLGLALSEALAQR-GFKVLMAMRNPDKAQKTLNGLTMKGLDVVPMKLDL 60 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLL------ 400 + + ++ + ++ +G D+LINN L ED K + K+ + Sbjct: 61 SQEKSITDFVEVVKREYGFVDVLINNAGILIDSEDGGNSSLFKTKASTLQKTFVTNTLGP 120 Query: 401 -IVEQYLFPLLKDS--GRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEE 565 ++ Q +FPL+K GR++NV++ LS + ++ L + + NLF E Sbjct: 121 FLLTQKIFPLMKQEGYGRIVNVSSGMAQLSEKQTASASYRISKTGLNM--VTNLFASE 176 >UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 282 Score = 47.6 bits (108), Expect = 3e-04 Identities = 37/137 (27%), Positives = 58/137 (42%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVAII T LG I ++L+E+ V D + G + IG +F +T Sbjct: 25 KVAIITGATQGLGADIARSLAEE-GACVLIAGLDADAGHALAAS---IGASARFAPTDVT 80 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 D L++ T G D+++NN T E+ ++D S I+ Q Sbjct: 81 DDAQLERAITTAIAAFGGLDLIVNNACSYDDAGLASTREQWARLLDVNLVSAAILAQKAA 140 Query: 422 PLLKDSGRVINVTNAYG 472 P L+ G V+N+ + G Sbjct: 141 PHLRRGGVVVNLGSVGG 157 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 47.6 bits (108), Expect = 3e-04 Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVA+I G G A + ++ VY EEEG K GL F Sbjct: 99 LAGKVALITGGARGQGEAEARLFAQH-GAHVYICDVLEEEGEKLAAELRGSGLQADFRFL 157 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +TD + I G D+LINN +++ T EE ++ K ++ Sbjct: 158 DVTDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLGM 217 Query: 410 QYLFPLLKDSGR--VINVTNAYG 472 Q PL+K SG +IN+ + G Sbjct: 218 QACAPLMKRSGNGSIINIGSTAG 240 >UniRef50_A7QKE7 Cluster: Chromosome chr2 scaffold_112, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_112, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 208 Score = 47.6 bits (108), Expect = 3e-04 Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 5/137 (3%) Frame = +2 Query: 275 IQMNHGSFDILIN--NTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLFPLLK--DSG 442 +Q F+ +N N + LK+ TYE+A+ I + Y V Q L PLL+ S Sbjct: 12 VQRLKEKFEYYVNDENVDMLKEIMK-RTYEKAEECIRTNYYGTQRVTQSLLPLLQLSPSS 70 Query: 443 RVINVTNAYGHLSNIKNDKWIKTL-TAPDLTVEQIDNLFVEEYLRSLENGKFDKKWFSDD 619 R++NV++ G L NI N + L +LT E++D + ++ +LR + K + Sbjct: 71 RIVNVSSLRGQLKNIHNHQVKAELENVGELTEEKLDKI-LQRFLRDFKEDKLGANGWPVI 129 Query: 620 GKIAEYKISMVARTALT 670 + YK+S A A T Sbjct: 130 A--SAYKVSKAAVNAYT 144 >UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellular organisms|Rep: Gluconate 5-dehydrogenase - Methanosarcina acetivorans Length = 255 Score = 47.6 bits (108), Expect = 3e-04 Identities = 33/146 (22%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVAI+ ++ LG+ +AL+ + + A EE+ + + +G+ ++ L Sbjct: 7 LTGKVAIVTGASSGLGVEFARALANQ-GANIAIIARREEKLKEVQKEIEKLGVTCRYYLC 65 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 + +K + + + G DIL+NN L D T E N+ID+ + Sbjct: 66 DVMKTEQIKNAVEQVVKDFGRIDILVNNAGLGLVDAADKTTDEMWHNMIDTNLNGVYFFA 125 Query: 410 QYL--FPLLKDSGRVINVTNAYGHLS 481 + + L + GR+IN+ + + +S Sbjct: 126 REVGKIMLRQKHGRIINIGSIHSTVS 151 >UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=33; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Shewanella oneidensis Length = 254 Score = 47.2 bits (107), Expect = 4e-04 Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 4/139 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA + G+ +G AIVK L+ + + S E + + G + A T Sbjct: 15 KVAFVQGGSRGIGAAIVKRLASEGAAVAFTYVSSEAQSQLLVDEVIAQGGKAIAIKADST 74 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 + A+++ + + G DI++NN L E+ T E+ + ++++ +S+ + Q Sbjct: 75 EPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENL-TLEDWERIVNTNVRSVFVASQE 133 Query: 416 LFPLLKDSGRVINV--TNA 466 + D GR+IN+ TNA Sbjct: 134 AALHMNDGGRIINIGSTNA 152 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 47.2 bits (107), Expect = 4e-04 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 2/139 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M K+A++ G + +GLA + L+++ VYFT + G GL FL Sbjct: 3 MQGKIALVTGGASGMGLAFTRRLAQE-GARVYFTDINGAAGHATESELQGAGLAVVFLRH 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +T + ++ + I G D+L+NN + + T E+ ++ KS+ + Sbjct: 62 DVTQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGC 121 Query: 410 QYLFPLLKD-SGRVINVTN 463 ++ L+K G +INV++ Sbjct: 122 KHGLALMKQKGGSIINVSS 140 >UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR; n=22; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 267 Score = 46.8 bits (106), Expect = 5e-04 Identities = 35/145 (24%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ K A++ G+ LGL + +AL E V ++ E+ +++ G+ ++ A Sbjct: 15 LTGKTALVTGGSRGLGLQLAQALGEA-GAKVILSSRKAEDLIESAAELKAAGIDVDWIAA 73 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIV 406 + + ++ +AD G DIL+NN ED P E V++ + I+ Sbjct: 74 DCSKEEDIRALADEAIKRLGHVDILVNNAGAAWGAPAEDHPV-EAWDKVMNLNIRGYFIL 132 Query: 407 EQYLFP---LLKDSGRVINVTNAYG 472 Q++ + + SGR+INV + G Sbjct: 133 SQHIAKHSMIARKSGRIINVASIAG 157 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 46.8 bits (106), Expect = 5e-04 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 4/141 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVAI+ G +G A AL+ + V D E N G ++A ++ Sbjct: 6 KVAIVTGGAQGIGRATALALARE-GAAVVIADRDAAATTALVEGINAWGGRALAVIADVS 64 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQ--CEDFPTYEEAKNVIDSKYKSLLIVEQY 415 D+ +IA+ + G D+L+NN ++Q + T + + +I+ + +V ++ Sbjct: 65 DESDAARIANDTVLEFGGIDLLVNNA-GIQQPGTIESTTLQLWQEIINVNLTGVFLVSRF 123 Query: 416 LFPLL--KDSGRVINVTNAYG 472 + P L + G ++NV + YG Sbjct: 124 VMPELRRRGGGAIVNVASVYG 144 >UniRef50_Q6H7D1 Cluster: Short-chain dehydrogenase/reductase protein-like; n=2; Oryza sativa|Rep: Short-chain dehydrogenase/reductase protein-like - Oryza sativa subsp. japonica (Rice) Length = 324 Score = 46.8 bits (106), Expect = 5e-04 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPK-FL 226 M +VA++ G +GL I + L+ NG V TA DE++G +A + GL F Sbjct: 24 METRVAVVTGGNRGVGLEICRQLAS--NGILVVLTARDEKKGSQAVKALEQSGLSGVIFH 81 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN 316 +TD+ ++ + + I+ G F+IL+NN Sbjct: 82 QLDVTDRSSIMLLVEFIRTKFGKFNILVNN 111 Score = 37.1 bits (82), Expect = 0.44 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 3/85 (3%) Frame = +2 Query: 353 YEEAKNVIDSKYKSLLIVEQYLFPLL--KDSGRVINVTNAYGHLSNIKNDKWIKTLTAPD 526 YE AK ++ + V L PLL +SG+VIN+T+ L I N+ IK L+ D Sbjct: 155 YEMAKECLEINFYGTKDVTDCLMPLLLLSNSGKVINLTSKISQLQFISNEGVIKVLSDID 214 Query: 527 -LTVEQIDNLFVEEYLRSLENGKFD 598 L+ E++ ++ +L+ ++G + Sbjct: 215 NLSDEKLKDV-ASIFLKDFKDGNLE 238 >UniRef50_Q4U978 Cluster: Short-chain dehydrogenase/reductase (SDR family member), putative; n=4; Theileria|Rep: Short-chain dehydrogenase/reductase (SDR family member), putative - Theileria annulata Length = 424 Score = 46.8 bits (106), Expect = 5e-04 Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 10/180 (5%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYF-----TASDEEEGLKATENFNNIGLYPKFL 226 KVAI+ G + +GL V L + V F A++ E +K+T++F+ LY F+ Sbjct: 139 KVAIVTGGYSGIGLETVFQLLKWNCKVVIFGRDKTRATNAIERMKSTKSFDENNLY--FI 196 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 + + ++K A + D LINN P + KN ++SK+ + + Sbjct: 197 EMDLDNLTSVKNAASSFLNMFDRLDFLINNAG----VSTGPL--KNKNGLESKFSTNFLG 250 Query: 407 EQYLFPLLKD-----SGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYL 571 YL LL D GRVI++++ ++ + KNDK +T + L ++ +N + L Sbjct: 251 HFYLTNLLLDLLKKTEGRVISLSSIEHYMYDPKNDKLFETKSTTSLQLDNRNNYYARSKL 310 >UniRef50_Q2UT07 Cluster: Dehydrogenases with different specificities; n=1; Aspergillus oryzae|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 239 Score = 46.8 bits (106), Expect = 5e-04 Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 5/179 (2%) Frame = +2 Query: 65 VAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITD 244 VA++ + +G A+ + L+ + + V TA + E G K G + ++ Sbjct: 3 VALVTGANSGIGEAVARQLARQPDHHVIVTARNLEAGEKVAAAIVEEGNSASAVRLDLSS 62 Query: 245 KPALKKIADTIQMNHGSFDILINNTED-LKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 ++ +A+ ++ +G DIL+NN L D E D+ ++ L Sbjct: 63 DESISTVAEHVKEAYGKLDILVNNAGTFLDHRSDLSVRENLTMTFDTNVIGTAVLTDALL 122 Query: 422 PLLKDSG--RVINVTNAYGHLSNIKNDKW-IKTLTAPDLTVEQID-NLFVEEYLRSLEN 586 LL+ S RV+ V++ G L+ ++ W ++ + + + N+ V Y R+L++ Sbjct: 123 DLLRQSSAPRVVFVSSVLGSLTLSNDENWPLRHIVSKAYKSSKAALNMLVLHYSRALQD 181 >UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteobacteria|Rep: Acetoacetyl-CoA reductase - Acinetobacter sp. (strain RA3849) Length = 248 Score = 46.8 bits (106), Expect = 5e-04 Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 6/144 (4%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKAL---SEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 QKVA++ +G I + L K+ TV D E+ +E F + + +F+L Sbjct: 4 QKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDV--RFVL 61 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIV 406 + + A G D+L+NN + +YE+ VID+ K+L V Sbjct: 62 TDLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTV 121 Query: 407 EQYLF--PLLKDSGRVINVTNAYG 472 Q +F L + SGR++N+++ G Sbjct: 122 TQPVFNKMLEQKSGRIVNISSVNG 145 >UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14; cellular organisms|Rep: Short-chain alcohol dehydrogenase - Zymomonas mobilis Length = 248 Score = 46.4 bits (105), Expect = 7e-04 Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 4/142 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K+ +I ++ LG + LS+ L TV A EE + G + +T Sbjct: 8 KIVVITGASSGLGAETARHLSD-LGATVVLGARREERIATLANSIVAKGGQALAIKTDVT 66 Query: 242 DKPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 D+ ++K + DT +G D+L+NN L E +E + ++D K +L Sbjct: 67 DRESVKNLVDTAVKTYGRVDVLLNNAGVMPLSPLEKL-RVDEWELMVDVNIKGVLYGIAA 125 Query: 416 LFPLLKDS--GRVINVTNAYGH 475 P +K G +INV++ GH Sbjct: 126 ALPHMKSQKFGHIINVSSVAGH 147 >UniRef50_Q13GU3 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 257 Score = 46.4 bits (105), Expect = 7e-04 Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 12/156 (7%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K A++ G LGL I + L+ L V A D + N+G L +T Sbjct: 13 KFALVTGGARGLGLEIAQQLAT-LGAHVIIGARDTAKAEAVATELRNLGHAVSALKLDVT 71 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPT------YEEAKNVI----DSKYK 391 + I HG DILINN L D T E NV+ ++ + Sbjct: 72 SDEDRQAAYAEIDRAHGRLDILINNAGILLDSPDGGTPATRQPSEALPNVVRDTFEANFF 131 Query: 392 SLLIVEQYLFPLLKDS--GRVINVTNAYGHLSNIKN 493 + + + Q L PL++ S GR++NV++ G L+++ + Sbjct: 132 APVFLTQTLLPLIRRSSAGRIVNVSSIRGSLAHLSD 167 >UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Anaeromyxobacter|Rep: Short-chain dehydrogenase/reductase SDR - Anaeromyxobacter sp. Fw109-5 Length = 342 Score = 46.4 bits (105), Expect = 7e-04 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 4/138 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K+A++ G+ LGL + + L + V A DEEE +A + G+ L +T Sbjct: 33 KIALVTGGSRGLGLLVARELGRR-GMRVVVLARDEEELERARSSLAAEGIDVTALPCDVT 91 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY--EEAKNVIDSKYKSLLIVEQY 415 D+ ++ + ++ N G D+L+NN + Q T ++ + +D + L + Sbjct: 92 DEEGIQGLVADVEQNLGPIDVLVNNA-GIIQVGPVETMKPDDYRRAMDVMFWGALNAAEA 150 Query: 416 LFPLLKD--SGRVINVTN 463 + P ++ G ++NVT+ Sbjct: 151 VLPGMRQRRRGTIVNVTS 168 >UniRef50_A3XJH6 Cluster: D-mannonate oxidoreductase; n=7; Bacteroidetes|Rep: D-mannonate oxidoreductase - Leeuwenhoekiella blandensis MED217 Length = 271 Score = 46.4 bits (105), Expect = 7e-04 Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 10/153 (6%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ K+ +I T +LG A+ ++L+ V ++ + ++ G ++ Sbjct: 6 SVENKIIVISGATGVLGEAMTRSLAAA-GAHVVILGRNQAKVDALVDSIKQDGDQASGVV 64 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTY-------EEAKNVIDSK 385 A +T K AL + D I + G D+LIN ++K P EE + VID Sbjct: 65 ADVTSKAALIEAKDEIANHLGYIDVLINAAGGNMKGALILPEQTLADADVEEMRKVIDLN 124 Query: 386 YKSLLIVEQYLFPLLKDS--GRVINVTNAYGHL 478 Y + Q PLL+ S G V+N+++ HL Sbjct: 125 YIGSFLPTQVFLPLLEKSKKGSVLNISSVAAHL 157 >UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacteroidetes|Rep: Acetoin(Diacetyl)reductase - Croceibacter atlanticus HTCC2559 Length = 254 Score = 46.4 bits (105), Expect = 7e-04 Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 4/141 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA++ T +G + K L + TV D E G K E G+ ++ +T Sbjct: 7 KVAVVTGATGGIGFEVAKRLGQD-GYTVVLNGIDHETGAKRVEELTAEGMTAEYYGFDVT 65 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP--TYEEAKNVIDSKYKSLLIVEQY 415 + + I +G D+L+NN L F T E +NV+ S+ + Sbjct: 66 KEEDVTSNIKAIGEKYGRIDVLVNNAGGLGGRSRFEEMTTEFYRNVMALNLDSVFFASRA 125 Query: 416 LFPLLKDSGR--VINVTNAYG 472 P LK+ +IN T+ G Sbjct: 126 AIPFLKNGEHPSIINYTSNAG 146 >UniRef50_A0YGX3 Cluster: Putative 3-oxoacyl-[ACP] reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Putative 3-oxoacyl-[ACP] reductase - marine gamma proteobacterium HTCC2143 Length = 249 Score = 46.4 bits (105), Expect = 7e-04 Identities = 43/138 (31%), Positives = 65/138 (47%), Gaps = 4/138 (2%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATEN-FNNIGLYPKFLLA 232 + KV ++ + +G AI KA E+ V D + A N F++ L K L Sbjct: 7 NNKVVLVTGAASGIGEAIAKAFLEQ-GAEVIVVDLD----ISALNNCFDSYDL-AKSLQQ 60 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA-KNVIDSKYKSLLIVE 409 +T A IAD + N G DIL+NN E T +E + ++D ++ + Sbjct: 61 DLTVANAAATIADWVARNGGRLDILVNNAGRALPSEIGTTTDELWQTMMDINVNAMFRLT 120 Query: 410 QYLFPLLKDS--GRVINV 457 + L PLLKDS GR+IN+ Sbjct: 121 RELLPLLKDSDAGRIINL 138 >UniRef50_Q7XIR1 Cluster: Carbonyl reductase-like protein; n=5; Magnoliophyta|Rep: Carbonyl reductase-like protein - Oryza sativa subsp. japonica (Rice) Length = 373 Score = 46.4 bits (105), Expect = 7e-04 Identities = 56/217 (25%), Positives = 90/217 (41%), Gaps = 33/217 (15%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNG-TVYFTASDEEEGLKATENFNNIGLYPKFL 226 T+ +++A++ G +GL + + L+ L G TV TA DE+ G A E+ + + Sbjct: 73 TIPERLAVVTGGNRGIGLEVCRQLA--LQGVTVILTARDEKRGKDAVESLCHESNLSNII 130 Query: 227 LAQ--ITDKPALKKIADTIQMNHGSFDILINNT---------EDLKQCEDFPTY---EEA 364 Q I D + +A I G DIL+NN + L+ P +A Sbjct: 131 FHQLDILDGNSRASLARYINSRFGKLDILVNNAGVGGVAVDQDGLRALNIDPRVWLSGKA 190 Query: 365 KNVIDS---------------KYKSLLIVEQYLFPLLKDS---GRVINVTNAYGHLSNIK 490 N+I S Y L + + L PLLK S R++N T+ L I Sbjct: 191 VNLIQSVIVQTYDEAVKCLNTNYYGLKWITEALLPLLKQSPSGARIVNTTSLRSELKRIP 250 Query: 491 NDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKFDK 601 N+K L D+ E + E+L L+N + ++ Sbjct: 251 NEKLRDELRNIDIWDEARIEAMLNEFLLDLKNERLEE 287 >UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W; n=2; Saccharomyces cerevisiae|Rep: Uncharacterized oxidoreductase YDL114W - Saccharomyces cerevisiae (Baker's yeast) Length = 308 Score = 46.4 bits (105), Expect = 7e-04 Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 4/142 (2%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A+I G++ LG + K LS ++N + A + A +NNI Y IT Sbjct: 41 ALITGGSSGLGFELAKELSRRINKVI--VADIQSFPTFAQVEYNNIFYYQ----CDITSL 94 Query: 248 PALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVID-SKYKSLLIVEQYL 418 +K + I+ +HG+ +I+INN +K+ E T +E + +ID + + I+ + Sbjct: 95 DEIKNLKKAIERDHGNINIIINNAGVAHIKKLEHM-TNKEVEQLIDINLIGAYRIISTFA 153 Query: 419 FPLLKD-SGRVINVTNAYGHLS 481 ++ + G +IN+ + G L+ Sbjct: 154 EDMIDNREGFIINIASVLGELT 175 >UniRef50_Q5UX46 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Halobacteriaceae|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 232 Score = 46.0 bits (104), Expect = 0.001 Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 5/149 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ +V ++ T +G AI L + L+ TVY A D ++ ++AT+ + I L Sbjct: 8 SLDSQVVLVTGATRGIGKAIADGLVD-LDATVYAGARDTDD-IEATDR-HAIEL------ 58 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNT---EDLKQCEDFPTYEEAKNVIDSKYKSLL 400 +TD + D I+ G D+L+NN + + + PT + + +D+ + + Sbjct: 59 -DVTDDDGMVAAVDRIEREQGRLDVLVNNAGVMDSREPLDGMPT-DVIDHTLDTNLRGAV 116 Query: 401 IVEQYLFPLL--KDSGRVINVTNAYGHLS 481 ++ +Y PLL + GR++ +++ G ++ Sbjct: 117 LMTKYALPLLLAEAGGRIVAMSSGLGAIT 145 >UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=17; Streptococcus|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Streptococcus pneumoniae Length = 253 Score = 45.6 bits (103), Expect = 0.001 Identities = 42/144 (29%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTAS-DEEEGLKA--TENFNNIGLYPKFLLA 232 K +I T+ +G AI +A E+ V D E LKA E F N ++ FLL Sbjct: 3 KNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKAEFAETFPNQTVWT-FLL- 60 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAK--NVIDSKYKSLLIV 406 +TD +K + I G DIL+NN + YEE ++D+ K L+ V Sbjct: 61 DVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYEELDMLTMLDTNVKGLMAV 120 Query: 407 EQYLFPLL--KDSGRVINVTNAYG 472 + P + + G +IN+ + G Sbjct: 121 TRCFLPAMVKANQGHIINMGSTAG 144 >UniRef50_Q6SHU1 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=1; uncultured bacterium 311|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - uncultured bacterium 311 Length = 285 Score = 45.6 bits (103), Expect = 0.001 Identities = 41/184 (22%), Positives = 85/184 (46%), Gaps = 3/184 (1%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNI-GLYPKFLLAQI 238 K +I T+ +G + ALSEK ++F A ++++ + TE + G P ++A + Sbjct: 7 KNCLITGATSGIGRSTALALSEK-GANIFFIARNQQKAEELTEEVERVSGKSPNAIIADL 65 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 + +++ A+ + + D+L+NN + E T + + V + + ++ L Sbjct: 66 SSFKQIERAAEEFKSLNKPIDVLLNNA-GIMNTERRVTEDGLEEVFAVNHLAYFLLTNLL 124 Query: 419 FPLLKDSG--RVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGK 592 + +SG RV+NV++ H +++K++ DL E+ +F L N Sbjct: 125 IEKILESGLKRVVNVSSD-AH-------RFLKSMNFDDLQSEKEFKMFAAYGQSKLANIL 176 Query: 593 FDKK 604 F +K Sbjct: 177 FTRK 180 >UniRef50_Q1NAB3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas sp. SKA58|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas sp. SKA58 Length = 250 Score = 45.6 bits (103), Expect = 0.001 Identities = 36/144 (25%), Positives = 70/144 (48%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNI-GLYPKFLL 229 + ++A+I + +GLA + +E+ G A E+ L + F ++ G + + Sbjct: 4 LDARIALITGAASGIGLATARRFAEE--GAKVVMADHNEDALSSV--FASLRGDGHQTVT 59 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIV 406 +TD+ A +A+ I G DIL+NN K T E+ +++I S+ + Sbjct: 60 MDVTDERAWAALAERIDAQFGKLDILVNNAGFGKFASITDTTLEQWRSIIAVNLDSVFLG 119 Query: 407 EQYLFPLLKDSGR--VINVTNAYG 472 +Y+ PLL SG+ ++N+++ G Sbjct: 120 TKYMMPLLAASGQGAIVNMSSIRG 143 >UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella baltica OS155|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella baltica OS155 Length = 251 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/143 (21%), Positives = 68/143 (47%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVA+I + +G I +A + + + ++++ + N+G + A Sbjct: 4 LTGKVALITGASRGIGAGIAEAFAIEGADLIINYRTNDDAAFRVVSKLKNLGRKVVAIRA 63 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVI-DSKYKSLLIVE 409 ++ + ++ + Q+ G DIL+NN ++ +EA ++I + K + Sbjct: 64 DVSKRSEIQNLIHLAQIEFGRIDILVNNAGINQRGWFNEVTDEAWDMIMGTNLKGPFMCC 123 Query: 410 QYLFPLLK--DSGRVINVTNAYG 472 Q +FPL+K GR+IN+++ G Sbjct: 124 QEVFPLMKANGGGRIINISSVAG 146 >UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=2; Bacillus|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 252 Score = 45.2 bits (102), Expect = 0.002 Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 6/152 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KV ++ G+ +G I +A E+ V A D +A N+ + A Sbjct: 5 LKDKVVLVTGGSKGIGKGIAQAFVEE-GAKVAIVARDAHGLQEAKRQLGNV----LTIQA 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN----TEDLKQCEDFPTYEEAKNVIDSKYKSLL 400 +TDK +K+ + +G+ DIL+NN L + +EEA ++ Y S + Sbjct: 60 DVTDKNEREKVFSQLLETYGTIDILVNNAGGSNGGLISETELSLFEEAFSL---NYFSAV 116 Query: 401 IVEQYLFPLL--KDSGRVINVTNAYGHLSNIK 490 Q P++ K SG +IN+++ +G S K Sbjct: 117 HFSQLALPVMKAKQSGAIINISSIFGRESGGK 148 >UniRef50_Q1ITR9 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 366 Score = 45.2 bits (102), Expect = 0.002 Identities = 38/166 (22%), Positives = 76/166 (45%), Gaps = 6/166 (3%) Frame = +2 Query: 2 IFISRCVFKAVAFGI*TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLK 181 + + R ++K F ++ K+A++ + LGLA+ + L+ + + A DE E Sbjct: 26 VLLGRAIWKG--FREISLRGKIALVTGSSRGLGLAMAQELARE-GARLVICARDEAELRW 82 Query: 182 ATENFNNIGLYPKFLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLK----QCEDFP 349 A E IG + + D+ ++K+ + I+ +G+ D+LINN ++ + Sbjct: 83 AQEELQAIGAEVLAVPCDVGDREQVRKMFEQIRARYGALDVLINNAGVIQVGPLHSQTIE 142 Query: 350 TYEEAKNVI--DSKYKSLLIVEQYLFPLLKDSGRVINVTNAYGHLS 481 +EEA V+ Y +L + SG + N+T+ G ++ Sbjct: 143 DFEEAMRVMFWGLVYPTLEAIRDM---RAMGSGHIANITSIGGRIA 185 >UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MWYL1|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 45.2 bits (102), Expect = 0.002 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGL-KATENFNNIGLYPKFLL 229 ++ KV ++ + +G A+ + L+E V EE+GL +A +G Sbjct: 4 LTNKVVLVTGASRGIGRALAEGLAEHGADVVICDLPREEKGLNEAKSAIEKLGRKCWVFG 63 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQ--CEDFPTYE-EAKNVIDSKYKSLL 400 A ITDK A++ + G D+L+NN LK ED + +A ++ K LL Sbjct: 64 ADITDKSAVENMVAQATEQAGHIDVLVNNAGILKPSLLEDLSEGDWDAHFAVNG--KGLL 121 Query: 401 IVEQYLFPLLKD--SGRVINVTN 463 V + P ++ +GR+IN+ + Sbjct: 122 FVTNAVLPQMRQRKNGRIINIAS 144 >UniRef50_Q0UAH4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 266 Score = 45.2 bits (102), Expect = 0.002 Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 5/144 (3%) Frame = +2 Query: 62 KVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYP--KFLLA 232 K +++ G N +G I L + V+ +A +G A EN N L +FL Sbjct: 6 KEIVLVTGANSGIGFEIAHQLLARGTYHVFLSARSSSKGKAALENLQNRNLPGSIEFLHL 65 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQ 412 + + A I HG DIL+NN + D E ++ D ++ + Sbjct: 66 DVQSDEHIANAASRIAEAHGKLDILVNNAA-IAFSTDGTERERLRDSFDINATGPYLLTK 124 Query: 413 YLFPLLKDSG--RVINVTNAYGHL 478 L P L+ S R+IN+++ G L Sbjct: 125 ALIPALRKSSNPRIINISSGAGSL 148 >UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Short chain dehydrogenase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 269 Score = 45.2 bits (102), Expect = 0.002 Identities = 31/141 (21%), Positives = 62/141 (43%), Gaps = 6/141 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + K+AI+ T+ +G+ I K + + V EE+G +N G + Sbjct: 6 LKDKIAIVTGSTSGIGIGIAKLYAAE-GAKVVICGRREEKGQAVVDNITKEGGESSYHFF 64 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE---DFPTYEEAKNVIDSKYKSLLI 403 IT+ +++K+ D +G DIL+NN ++ + D T + + +S + Sbjct: 65 DITNTNSIEKLIDDTAEKYGKIDILVNNAANVALKDGNIDELTIDMWDAIFESDLRGTFY 124 Query: 404 VEQYLFPLL---KDSGRVINV 457 + + P L ++ G +IN+ Sbjct: 125 ATKCVIPYLQKNENGGSIINI 145 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 44.8 bits (101), Expect = 0.002 Identities = 40/144 (27%), Positives = 59/144 (40%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M KVAI+ G+ +G A+VK K V F EEG K G F++ Sbjct: 5 MKDKVAIVTGGSTGIGKAVVKEFVSK-GVKVVFCGRRLEEGKKLESEIRAEGGDVYFVVC 63 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIV 406 +T +KK+ D G D INN + Y E V++ K + Sbjct: 64 DVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWLS 123 Query: 407 EQYLFP-LLK-DSGRVINVTNAYG 472 +Y P ++K G V+NV++ G Sbjct: 124 MKYQIPEMIKMGGGVVVNVSSISG 147 >UniRef50_Q2JGQ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. (strain CcI3) Length = 244 Score = 44.8 bits (101), Expect = 0.002 Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 8/150 (5%) Frame = +2 Query: 68 AIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITD 244 A ++ G+N LG A +AL+ +L V TA ++ KA + G + +T Sbjct: 3 AALVTGSNRGLGFATAQALA-RLGHRVLVTAREQAAADKAAADLTAQGFDADAIALDVTS 61 Query: 245 KPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAK-NVIDSKYKSLLI----VE 409 ++ + DIL+NN L + D +E A ++ Y + + V Sbjct: 62 PDSIAAATRRVAELPAGLDILVNNAGILPEATDGEQHEFASLDLFGKTYATNVFGPVAVT 121 Query: 410 QYLFPLLKDS--GRVINVTNAYGHLSNIKN 493 + L PLL+ S GR++NV+ G LS+ N Sbjct: 122 EALLPLLRRSPAGRIVNVSTTMGSLSDQAN 151 >UniRef50_A1ZT55 Cluster: Carbonyl reductase, NADPH 1; n=1; Microscilla marina ATCC 23134|Rep: Carbonyl reductase, NADPH 1 - Microscilla marina ATCC 23134 Length = 229 Score = 44.8 bits (101), Expect = 0.002 Identities = 33/148 (22%), Positives = 67/148 (45%), Gaps = 3/148 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K+ ++ G +G + + L+ + V TA ++ +A N GL + + ++ Sbjct: 5 KIILVTGGNRGIGFEMCRQLAT-MGHKVILTARTSDKVQEAVVRLANTGLKVQGEVLDVS 63 Query: 242 DKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 + K A I+ + D+LINN LK+ T + + + + + L Sbjct: 64 KTGSFKVFAQRIEAKYAYLDVLINNAGIFLKESLQSLTEQVLDETLKTNLYGPIFFSREL 123 Query: 419 FPLLKDS--GRVINVTNAYGHLSNIKND 496 PLL +S GR++NV++ G +S++ + Sbjct: 124 IPLLHNSKGGRIVNVSSFLGTMSDMNRN 151 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 44.8 bits (101), Expect = 0.002 Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KV ++ G +GL L+ + TVY + +EE G +A G FL Sbjct: 4 VNDKVVLVTGGAMGMGLTHCTLLARE-GATVYLSDMNEELGHQAVAEIRRQGGKAHFLHL 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE--DLKQCEDFPTYEEAKNVIDSKYKSLLI- 403 +T++ DTI D L+NN LK +D + EE + + +S+ + Sbjct: 63 DVTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQD-TSNEEWDRIFEINVRSVFLG 121 Query: 404 VEQYLFPLLK-DSGRVINVTNAYG 472 + P+ K G ++NV++ YG Sbjct: 122 TRAVIEPMRKAHKGCIVNVSSIYG 145 >UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n=90; cellular organisms|Rep: D-beta-hydroxybutyrate dehydrogenase - Rhizobium meliloti (Sinorhizobium meliloti) Length = 258 Score = 44.8 bits (101), Expect = 0.002 Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K A+I T+ +GLAI + L+ K + + ++ + GL +L Sbjct: 3 KTAVITGSTSGIGLAIARTLA-KAGANIVLNGFGAPDEIRTVTD-EVAGLSSGTVLHHPA 60 Query: 242 DKPALKKIADTIQM---NHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 D +IAD + M G DIL+NN + +++ EDFP + + + + S + Sbjct: 61 DMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTI 120 Query: 407 EQYLFPLLKDS-GRVINVTNAYG 472 + P+ K GR+IN+ +A+G Sbjct: 121 RGAIPPMKKKGWGRIINIASAHG 143 >UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=2; Candidatus Pelagibacter ubique|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Pelagibacter ubique Length = 245 Score = 44.4 bits (100), Expect = 0.003 Identities = 41/149 (27%), Positives = 75/149 (50%), Gaps = 3/149 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ K I+ + +G +IV+ L++ + T + E+ + E FNNI + KF + Sbjct: 3 SLKDKNIIVTGASGGIGNSIVEKLNQN-GANILATGTRIEKLEELKEKFNNIKIL-KFDI 60 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP-TYEEAKNVIDSKYKSLLIV 406 +Q DK + I + + GS D ++NN K + EE VI+ S ++ Sbjct: 61 SQ-HDKIE-EFIENATKELGGSLDCIVNNAGITKDNLTIRMSLEEWSKVININLTSTFLM 118 Query: 407 EQY-LFPLLKD-SGRVINVTNAYGHLSNI 487 +Y + +LK+ SG++IN+T+ GH N+ Sbjct: 119 CKYSIKKMLKNKSGKIINITSVVGHTGNV 147 >UniRef50_A7CNG7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia pickettii 12D|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia pickettii 12D Length = 228 Score = 44.4 bits (100), Expect = 0.003 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 2/134 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S K A+I G+ LGL I +AL E+ + +A +E +A + ++G+ ++ A Sbjct: 10 LSGKTALITGGSRGLGLQIAEALGEQ-GARIVLSARKADELKEAQAHLKSLGIEADWIAA 68 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIV 406 + ++++AD G DIL+NN ED P E V++ + L ++ Sbjct: 69 DGAVEADIQRLADEALAKLGHVDILVNNAGATWGAPAEDHPV-EAWDKVMNLNIRGLFLL 127 Query: 407 EQYLFPLLKDSGRV 448 Q + D +V Sbjct: 128 TQQIGKRSDDPAQV 141 >UniRef50_A6Q6X0 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Sulfurovum sp. (strain NBC37-1) Length = 270 Score = 44.4 bits (100), Expect = 0.003 Identities = 36/142 (25%), Positives = 71/142 (50%), Gaps = 3/142 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KV +I ++ +G + L++ NG + + S + E ++A EN L P +L +T Sbjct: 3 KVVLITGASSGMGKRTSEFLAQ--NGYIVYAGSRKAESMEAKEN-----LKPVYL--DVT 53 Query: 242 DKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 D ++++ +TI N G D+L+NN L + T EE + ++ LL + + Sbjct: 54 DTESIQQAVETIIQNEGKIDVLVNNAGYGLLSTVEDGTDEEMFDQLNVNVFGLLKATRAV 113 Query: 419 FPLLK--DSGRVINVTNAYGHL 478 P ++ SG +I++++ G + Sbjct: 114 LPHMRAAKSGVIIDISSFLGKM 135 >UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Shewanella|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella sp. (strain ANA-3) Length = 292 Score = 44.4 bits (100), Expect = 0.003 Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 5/151 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENF-NNIGLYPKFL 226 ++ KV +I T+ +GLA L+E+ + E EG + F ++ F Sbjct: 33 SLKGKVGLITGSTSGIGLATAHVLAEQGCHLILHGLMPEAEGRRLAAEFAEQYHIHTYFS 92 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLL 400 A + D ++ D GS DIL+NN + + FP ++ ++I S Sbjct: 93 NADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFP-IDKWNDIIAINLSSAF 151 Query: 401 IVEQYLFPLLKDS--GRVINVTNAYGHLSNI 487 Q P + + GR+IN+ + +G ++++ Sbjct: 152 HTIQQAVPAMAEKRWGRIINIASVHGLVASV 182 >UniRef50_A7PZ82 Cluster: Chromosome chr15 scaffold_40, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr15 scaffold_40, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 244 Score = 44.4 bits (100), Expect = 0.003 Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 15/132 (11%) Frame = +2 Query: 134 NG-TVYFTASDEEEGLKATENFNNIGL-YPKFLLAQITDKPALKKIADTIQMNHGSFDIL 307 NG TV TA DE+ G++A EN L + + +TD ++ +AD I+ G DIL Sbjct: 108 NGVTVVLTARDEKRGVEALENLKESDLSHVIYHQLDVTDPASVDSLADFIKTQFGGLDIL 167 Query: 308 INNTEDLKQCEDFPTYEEA-----------KNVIDSKYKSLLIVEQYLFPLLK--DSGRV 448 NNT + P + K+V Y V PLL+ DS R+ Sbjct: 168 TNNTGIMGMIITDPDALVSGKAVIKITIWLKHVSKVNYSGAQKVIGAFIPLLQLSDSPRI 227 Query: 449 INVTNAYGHLSN 484 +N++++ G+L + Sbjct: 228 VNISSSTGNLKS 239 >UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 274 Score = 44.4 bits (100), Expect = 0.003 Identities = 43/171 (25%), Positives = 70/171 (40%), Gaps = 3/171 (1%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVAI+ GT+ +G A+ + L K TV+ S +E KA ++F +FL +T Sbjct: 8 KVAIVTGGTSGIGYAVSEELL-KRGATVWVIGSRQESVDKARKSFAAY-KNTRFLAVDVT 65 Query: 242 DKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 +K + D G D L NN + + T E + ID ++ + Sbjct: 66 VADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWGVVYGVHFA 125 Query: 419 FP--LLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEE 565 P L + SG ++N ++ G + + T A E + F EE Sbjct: 126 LPVMLAQKSGHIVNTSSIAGIVPLPSQAAYCATKHAVTALTESLRYEFFEE 176 >UniRef50_Q39A34 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 44.0 bits (99), Expect = 0.004 Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 3/138 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S KVA+I G + +GL I + + + V D ++G A + F+ A Sbjct: 4 LSGKVAVITGGASGIGLGIARGMVDA-GANVVLVGRDRDKGDAAIASLPGGSERGLFVPA 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 IT + A + + G DIL+NN +++Q T ++ +ID+ Sbjct: 63 DITRRDACMTAIEQAERRFGRLDILVNNAGMNIRQQGHELTADDWYRIIDTNLSGAHFCA 122 Query: 410 QYLFPLLK--DSGRVINV 457 Q + P + G++IN+ Sbjct: 123 QAIHPAFRRAGGGKIINI 140 >UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=3; Bacteria|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - Psychromonas sp. CNPT3 Length = 244 Score = 44.0 bits (99), Expect = 0.004 Identities = 38/152 (25%), Positives = 74/152 (48%), Gaps = 7/152 (4%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 TM +V ++ + +G AI + L TV TA+ E+ +E + G K + Sbjct: 2 TMKDQVVLVTGASRGIGRAIAEKFVS-LGATVLGTATSEKGATAISEYLGDSG---KGFV 57 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN---TED--LKQCEDFPTYEEAKNVIDSKYKS 394 +TD ++ + I+ ++ DIL+NN T D L + +D +E ++ID+ Sbjct: 58 LNVTDNDSIAALFAVIKKDYIGVDILVNNAGITRDNLLMRMKD----DEWNDIIDTNLTP 113 Query: 395 LLIVEQYLF-PLLKD-SGRVINVTNAYGHLSN 484 + + + + P++K +GR+IN+ + G + N Sbjct: 114 IFKMSKAVMRPMMKKRAGRIINIGSVVGTMGN 145 >UniRef50_A6WFA8 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Kineococcus radiotolerans SRS30216 Length = 231 Score = 44.0 bits (99), Expect = 0.004 Identities = 47/181 (25%), Positives = 78/181 (43%), Gaps = 7/181 (3%) Frame = +2 Query: 77 INGTN-ILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDKPA 253 I G N LG + L E TV A D G A + L +F+ +TD + Sbjct: 6 ITGANKSLGYETARRLVEA-GHTVLLGARDPGRGRAAAD-----ALGVRFVQIDVTDDAS 59 Query: 254 LKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIVEQYLFPL 427 ++ A + + G+ D+L+NN + D T +A V D ++ V + PL Sbjct: 60 VEAAAADVAAHEGAIDVLVNNAGVVGPHAAADELTAADALAVYDVNVFGVVRVTRAFLPL 119 Query: 428 LKDSGR--VINVTNAYGHLSNIKN-DKWIKTLTAPDLTVEQID-NLFVEEYLRSLENGKF 595 L+ S V+NVT+ G + + D+ T AP T + + +Y ++L + KF Sbjct: 120 LRKSANPVVVNVTSGMGSFAATHDPDRVESTFAAPLYTSSKAALTMLTTQYAKALPDVKF 179 Query: 596 D 598 + Sbjct: 180 N 180 >UniRef50_A6EJT9 Cluster: Putative dehydrogenase; n=1; Pedobacter sp. BAL39|Rep: Putative dehydrogenase - Pedobacter sp. BAL39 Length = 258 Score = 44.0 bits (99), Expect = 0.004 Identities = 41/161 (25%), Positives = 71/161 (44%), Gaps = 17/161 (10%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNG-TVYFTASDEEEGLKATENFNNIGLYPKFL 226 T +Q +A++ +G I KAL+E NG TVY + + G KA IG K + Sbjct: 10 TKNQLIALVTGANQGVGFQIAKALAE--NGYTVYVGSRNLSNGEKAAAE---IGGDTKAI 64 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNT------------EDLKQC--EDFPTYEEA 364 +T + + I+ G D+L+NN ED + + +E Sbjct: 65 QLDVTQSSTINAVVTRIERESGRLDLLVNNAAIAHAGQPGRTLEDATEAGKATKASLDEV 124 Query: 365 KNVIDSKYKSLLIVEQYLFPLLKDS--GRVINVTNAYGHLS 481 + V ++ ++ + Q PLL+ S R++NV++ G L+ Sbjct: 125 RTVWETNVFGVIAMTQAALPLLRKSAAARIVNVSSGLGSLT 165 >UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 269 Score = 44.0 bits (99), Expect = 0.004 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 4/160 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNI--GLYPKFL 226 + K +I GT +G AI L L G V DE++ A + G Sbjct: 29 IKDKKIVITGGTTGIGKAIADVLVS-LGGRVLIFGRDEKDFKNAVADIQKQFPGSEVYGT 87 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 A +T K ++KI + G DILINN +Y++ K +ID+ L Sbjct: 88 PADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAF 147 Query: 407 EQYLFPLLKD--SGRVINVTNAYGHLSNIKNDKWIKTLTA 520 Q +K SG +IN+ + K+ ++ T +A Sbjct: 148 AQEAASRMKQQKSGHIINIGSMSAESKEAKSTIYVATKSA 187 >UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Blastopirellula marina DSM 3645|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Blastopirellula marina DSM 3645 Length = 258 Score = 44.0 bits (99), Expect = 0.004 Identities = 35/148 (23%), Positives = 72/148 (48%), Gaps = 4/148 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFN-NIGLYPKFLL 229 +S + A++ G+ +G AI + L+E +V TA ++E A + + + + + Sbjct: 9 LSGRTALVTGGSKGIGKAIARGLAEA-GASVCITARHQQELETAAQEIGAGLDVRVAWRI 67 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 + D+ A+ +AD + G DIL NN + Q T E +V++ + S + + Sbjct: 68 CDMADRAAVDALADGVLEEFGQVDILFNNAGTNQPQLLVETTDESWDHVLEINFTSCMRL 127 Query: 407 EQYLFP--LLKDSGRVINVTNAYGHLSN 484 + L P + + GR+I++++ +SN Sbjct: 128 ARKLAPGMIERRWGRIIHLSSVLAVVSN 155 >UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Marinomonas sp. MED121|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Marinomonas sp. MED121 Length = 259 Score = 44.0 bits (99), Expect = 0.004 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 3/141 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 +++ + ++ G + +G A+VKAL+++ V F DEE G + +N N+ G+ F L Sbjct: 14 SLNARHVLVTGGASGIGEALVKALAQQ-GCAVSFFDIDEEAGEQLAQNLNSHGMKAHFEL 72 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN-TEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 +TD LK G+ L+NN D + + +E + K Sbjct: 73 VDLTDIEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFA 132 Query: 407 EQYLFPLLKDS--GRVINVTN 463 Q + PL+ ++ G +IN+++ Sbjct: 133 AQKVAPLMAEAGGGSIINMSS 153 >UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Flavobacteriaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leeuwenhoekiella blandensis MED217 Length = 246 Score = 44.0 bits (99), Expect = 0.004 Identities = 30/141 (21%), Positives = 70/141 (49%), Gaps = 4/141 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M+ + A++ G + LG AI + + VY +EE+ +A +N + + P ++ Sbjct: 1 MTIQTAVVTGGNSGLGYAIARKFCDA-GYKVYIIGRNEEKTRQAADNLGEL-VVP--IVF 56 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAK--NVIDSKYKSLLIV 406 + + A+ K+ D + G D+L+NN + +DF +A+ ++ + KS+ + Sbjct: 57 DLNNLEAIPKLIDELLQATGKIDVLVNNA-GINMKKDFAEVTDAEFDRILHTNVKSVFAI 115 Query: 407 EQYLFPLLKDS--GRVINVTN 463 + + +K + G ++N+++ Sbjct: 116 SREVVKSMKGNYGGSIVNISS 136 >UniRef50_Q22DT5 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Oligohymenophorea|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 282 Score = 44.0 bits (99), Expect = 0.004 Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 4/164 (2%) Frame = +2 Query: 65 VAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKF--LLAQ 235 + II+ G+N +G I++ L+ K + S E ++ I + K Sbjct: 13 IRIIVTGSNKGVGYGIIENLAAKPYHIIMACRSLERAN-ESRSKLLQIHPHAKIDSYELD 71 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 I ++ K I ++G DIL+NN+ + + F + + Y ++ + E+ Sbjct: 72 IDSTDSINKFVQQIHQHYGYVDILLNNSGMAFKGDAFGADVVEQTFRTNFYGTIDLTEKM 131 Query: 416 LFPLLKDSGRVINVTNAYGHLSNIKNDKWI-KTLTAPDLTVEQI 544 L P +K++G+VI V ++ G N+KN++ + + L P LT +Q+ Sbjct: 132 L-PYIKENGKVIFVGSSAGKYHNVKNNQAVLQQLQNPHLTKDQL 174 >UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 269 Score = 44.0 bits (99), Expect = 0.004 Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 4/145 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++S KVA++ G+ +G A K LSE V T +E K + +N + Sbjct: 24 SLSGKVALVTGGSRGIGFATAKVLSEN-GANVAITGKVQERLEKVSSEISNSFAIVADVR 82 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNT---EDLKQCEDFPTYEEAKNVIDSKYKSLL 400 K A+KKI + G DIL+NN +K+ + EE V+D Sbjct: 83 KTEDVKNAIKKIVE----KFGRLDILVNNAGVFPKIKKLHEIDD-EEWNEVLDVNLTGQF 137 Query: 401 IVEQYLFP-LLKDSGRVINVTNAYG 472 V + P L K SG +IN+++ G Sbjct: 138 RVTKEAIPHLQKTSGSIINISSDAG 162 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 44.0 bits (99), Expect = 0.004 Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 3/133 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 KVA++ G +G AI + +E NG V DEE G++ E GL F+ + Sbjct: 5 KVAVVTGGGQGIGAAIAQLFAE--NGMKVVIAEIDEEAGVEREEMLRERGLDVTFVKTDV 62 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP-TYEEAKNVIDSKYKSLLIVEQY 415 D+ ++K + +G D+L+NN + F EE + VI I +Y Sbjct: 63 ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122 Query: 416 LF-PLLKDSGRVI 451 ++K G VI Sbjct: 123 CAEEMIKRGGGVI 135 >UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; Rhizobium etli CFN 42|Rep: Putative oxidoreductase protein - Rhizobium etli (strain CFN 42 / ATCC 51251) Length = 315 Score = 43.6 bits (98), Expect = 0.005 Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KVAI+ ++ +G A + L+EK V +EE + E+ G + +A Sbjct: 4 LKNKVAIVTGASSGIGAATARGLAEK-GARVVLAGRNEERLSQIVEDITGSGGIASYKVA 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIV 406 TD + K + +G DIL+NN + +D + K +ID+ + L Sbjct: 63 DATDFESTKALVAFATTTYGPVDILVNNAGLMLFSYWKDAAVGDWNK-MIDTNLRGYLHA 121 Query: 407 EQYLFP--LLKDSGRVINVTNAYG 472 + P L + SGR++N+++ G Sbjct: 122 IAAVLPSMLERRSGRILNMSSIAG 145 >UniRef50_Q46N54 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 260 Score = 43.6 bits (98), Expect = 0.005 Identities = 31/140 (22%), Positives = 66/140 (47%), Gaps = 3/140 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S + A++ G++ +G AI A+ + V A + + A + +G+ + Sbjct: 14 LSGRQALVTGGSSGIGEAIATAMGQA-GARVILAARRQSQLDAAASRLDAMGIAVDTHVF 72 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 ++D A+ AD +Q HG+ DIL+N +L++ T + +D+ + + Sbjct: 73 DVSDLDAIPAAADALQQQHGTIDILVNAAGMNLRETYASVTPSSWRLQLDTHLGAPFFLT 132 Query: 410 QYLFPLLKDS--GRVINVTN 463 Q L P ++ GR++N+ + Sbjct: 133 QALAPAMQTQGWGRILNIAS 152 >UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=4; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Psychroflexus torquis ATCC 700755 Length = 269 Score = 43.6 bits (98), Expect = 0.005 Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 3/147 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ K+A++ G + +G A K + TV T D E+ KA++ +G+ K ++A Sbjct: 22 LNGKIAVVTGGNSGIGYASAKEFKSQ-GATVVITGRDSEKVAKASQE---LGV--KGIVA 75 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA-KNVIDSKYKSLLIVE 409 + A+ + ++ + G D+L N + EE + + +K Sbjct: 76 DVKSLSAIDDLVAQVKSDFGKVDVLFVNAGIFQPAPVGQISEEMFDHQMSINFKGAFFTT 135 Query: 410 QYLFPLLKDSGRVINVT--NAYGHLSN 484 + P+L D VIN++ NAY + N Sbjct: 136 EKFLPILNDGASVINLSSVNAYTGMPN 162 >UniRef50_A3ZTM1 Cluster: Probable short-chain dehydrogenase; n=1; Blastopirellula marina DSM 3645|Rep: Probable short-chain dehydrogenase - Blastopirellula marina DSM 3645 Length = 299 Score = 43.6 bits (98), Expect = 0.005 Identities = 25/87 (28%), Positives = 43/87 (49%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQ 235 ++KVA++ + LGLAI + L + TV TA D + A E+ + + A Sbjct: 31 NEKVALVTGASRGLGLAIARRLVRQ-GATVILTARDPADLAAAAESLKGLSGAAIPMAAD 89 Query: 236 ITDKPALKKIADTIQMNHGSFDILINN 316 +T +K++ I+ G D+L+NN Sbjct: 90 VTSDDDVKRLEKEIESRFGRLDLLVNN 116 >UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 43.6 bits (98), Expect = 0.005 Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 10/145 (6%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAI-VKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL- 229 S KV +I + +G A VK +E + ++D+ E K + +G P LL Sbjct: 7 SGKVVLISGSSKGIGQATAVKFAAEGAKIVLNGRSADDVE--KTRKLCMEVGAKPWDLLP 64 Query: 230 --AQITDKPALKKIADTIQMNHGSFDILINNTEDLK-QCEDFPTYEEAKNVID----SKY 388 IT++ +K + +T+ N G DILINN L+ +E +V+D S + Sbjct: 65 TVGDITNEDFVKMMVNTVIHNFGKLDILINNAGTLEVDMTGKEGWEMGVDVMDRSWNSNF 124 Query: 389 KSLLIVEQYLFP-LLKDSGRVINVT 460 KS+L++ Q P L+K G ++NV+ Sbjct: 125 KSVLMLTQAAMPHLIKTKGDIVNVS 149 >UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specificities; n=3; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 255 Score = 43.6 bits (98), Expect = 0.005 Identities = 36/144 (25%), Positives = 64/144 (44%), Gaps = 6/144 (4%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTV--YFTASDEEEGLKATENFNNIGLYPKF 223 ++ K+A++ G +G IV+ALSE+ Y + S E+ N G Sbjct: 2 SLKGKIALVTGGARGIGAGIVRALSEQGAKVAFNYVSPSSRAAAGSLVESLQNDGHEAFG 61 Query: 224 LLAQITD--KPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDSKYK 391 + A + D PA A DIL+NN D + E+ T E ++D + Sbjct: 62 IQADLADIQAPATLVSAVLSAFQTTQIDILVNNAGAGDNRPLEEV-TLESYTKLMDINVR 120 Query: 392 SLLIVEQYLFPLLKDSGRVINVTN 463 +++ + Q + P + GR+IN+++ Sbjct: 121 AVVFMTQAVLPYIPRGGRIINLSS 144 >UniRef50_Q0CE63 Cluster: Predicted protein; n=2; Pezizomycotina|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 252 Score = 43.6 bits (98), Expect = 0.005 Identities = 41/153 (26%), Positives = 66/153 (43%), Gaps = 6/153 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNI-LGLAIVKALSEKL-NGTVYFTASDEEEGLKATENFNNIGLYPKFL 226 MS K I+I G N +G AL+ + V + G KA E+ Sbjct: 1 MSVKKIILITGANSGIGYDTSYALANASPSNHVIMGCRNSTRGAKALEDLQARNPAGTLS 60 Query: 227 LAQ--ITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLL 400 L Q ++D +++ D I + G D+L+NN + E +E I++ Sbjct: 61 LVQLDVSDDASIRSAVDQISTDFGVLDVLVNNA-GIVITEPRERRDEMLTTINTNTVGPY 119 Query: 401 IVEQYLFPLLKDS--GRVINVTNAYGHLSNIKN 493 ++ + L PLL+ S R+INVT+ G +S N Sbjct: 120 VLTEQLLPLLQKSQDPRIINVTSRLGSISERAN 152 >UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=8; Pezizomycotina|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Aspergillus clavatus Length = 328 Score = 43.6 bits (98), Expect = 0.005 Identities = 28/140 (20%), Positives = 56/140 (40%), Gaps = 3/140 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALS-EKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ K AII G + +G A+ + E + + + +E + + IG L Sbjct: 82 LAGKRAIITGGDSGIGRAVAILFAMEGASSLIVYLPDEESDAQETKRRVQEIGKECHCLA 141 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLI 403 + K +K+ D G D+L+NN +D +EA + D+ Sbjct: 142 IDLRKKENCRKVVDVALQYMGGVDVLVNNAAFQHMVQDISELDEAQWERTFDTNIHPFFY 201 Query: 404 VEQYLFPLLKDSGRVINVTN 463 + +Y P ++ +IN ++ Sbjct: 202 LAKYTLPHMRSGSTIINCSS 221 >UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|Rep: Glucose 1-dehydrogenase - Thermoplasma volcanium Length = 261 Score = 43.6 bits (98), Expect = 0.005 Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 4/144 (2%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQ 235 + KVAI+ G++ +GLA+V AL + V + DE+ + +++F Sbjct: 5 TDKVAIVTGGSSGIGLAVVDAL-VRYGAKVVSVSLDEKSDVNVSDHFK----------ID 53 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +T++ +K+ + +G DIL+NN E PT E + +ID ++ Sbjct: 54 VTNEEEVKEAVEKTTKKYGRIDILVNNAGIEQYSPLHLTPT-EIWRRIIDVNVNGSYLMA 112 Query: 410 QYLFPLLK--DSGRVINVTNAYGH 475 +Y P++ G +IN+ + + Sbjct: 113 KYTIPVMLAIGHGSIINIASVQSY 136 >UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein) reductase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: 3-oxoacyl-(acyl-carrier protein) reductase - Entamoeba histolytica HM-1:IMSS Length = 265 Score = 43.2 bits (97), Expect = 0.007 Identities = 47/196 (23%), Positives = 83/196 (42%), Gaps = 10/196 (5%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGL-YPKFLLAQI 238 KVA+I GT+ +G AIV+ L+E+ V F +E G + NN F+ + Sbjct: 6 KVALITGGTSGIGEAIVRQLTEQ-KCNVIFIGRRKELGESISHELNNKHFGQIDFIPFDV 64 Query: 239 TDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQ 412 T+ + +Q + D+L+NN C++ T E + + KS+ + + Sbjct: 65 TNFKEYDSLVHIVQEKYNRLDLLVNNAGIVTYDTCDEL-TEETFDLIYQTNVKSVWQMTK 123 Query: 413 YLFPLLKDS-GRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLE-- 583 + LL+ S G V+N+ G +IK D + V I + +Y ++ Sbjct: 124 HFHNLLEQSYGAVVNI----GSDVSIKADPQYFGYSDSKAAVMHITKMMALQYAPNIRIN 179 Query: 584 ----NGKFDKKWFSDD 619 F ++W SD+ Sbjct: 180 AVCPGDTFVERWISDE 195 >UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase - Oceanobacillus iheyensis Length = 244 Score = 43.2 bits (97), Expect = 0.007 Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KVAII G +G + V+ L K V FT +EE GL N +G KF+ Sbjct: 4 LENKVAIITGGARGMGASHVR-LFAKEGAKVVFTDLNEEGGLALA---NELGENVKFVKQ 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +T+ + + + G ++L+NN L T E+ + +ID S+ + Sbjct: 60 DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLGM 119 Query: 410 QYLFPLLK--DSGRVINVTNAYG 472 + + P ++ SG ++N+++ G Sbjct: 120 KAVVPSMQKAGSGSIVNISSMNG 142 >UniRef50_Q026V1 Cluster: Transcriptional regulator, Fis family; n=1; Solibacter usitatus Ellin6076|Rep: Transcriptional regulator, Fis family - Solibacter usitatus (strain Ellin6076) Length = 311 Score = 43.2 bits (97), Expect = 0.007 Identities = 33/146 (22%), Positives = 67/146 (45%), Gaps = 4/146 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEG--LKATENFNNIGLYPKF 223 T S ++ +I GT +G AI ++ KL T D+ G KA + + Sbjct: 3 TNSSQIVLITGGTGGIGQAIAVRMA-KLGATTIVVGRDQARGEAAKAEIRTQSGNRSVEL 61 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 +LA ++ + ++++A +G D+L+NN L + + T + + + + + Sbjct: 62 MLADLSSQGDIRRLAGEFMARYGRLDVLVNNVGGL-YGKRWETVDGIECTLALNHLCPFL 120 Query: 404 VEQYLFPLLKDS--GRVINVTNAYGH 475 + L P+L+ R++N+ N+ GH Sbjct: 121 LTHLLLPVLRAGAPSRIVNI-NSEGH 145 >UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Clostridiales|Rep: Short-chain dehydrogenase/reductase SDR - Clostridium beijerinckii NCIMB 8052 Length = 260 Score = 43.2 bits (97), Expect = 0.007 Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 1/148 (0%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KV II G +G + + S + V F ++E G + E +F L I Sbjct: 6 KVCIITGGALGIGRCLTREFSN-VGAKVIFIDKNKEAGNENVEYIKRKDGEVEFFLGDIA 64 Query: 242 DKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 ++ L K A+ I + + D LINN + K +YE+ V+ + I+ Q L Sbjct: 65 EEDTLYKFAEFIIKKYKNIDYLINNACINKKGIISKCSYEDFNYVLKVGVTAPYILTQLL 124 Query: 419 FPLLKDSGRVINVTNAYGHLSNIKNDKW 502 +G ++N+++ ++S + + Sbjct: 125 MNNFNKNGAIVNISSTRAYMSQSDTESY 152 >UniRef50_A6EJ86 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Pedobacter sp. BAL39|Rep: Short-chain dehydrogenase/reductase SDR - Pedobacter sp. BAL39 Length = 287 Score = 43.2 bits (97), Expect = 0.007 Identities = 38/150 (25%), Positives = 69/150 (46%), Gaps = 7/150 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNI----LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPK 220 M++KV ++I GTN L V AL K+ T+ TA + KA N+ + Sbjct: 1 MNKKV-VLITGTNSGFGWLTANSVAALGHKVYATMRDTAGKNADKAKALAQVANVTV--- 56 Query: 221 FLLAQITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSL 397 L +TD+ ++K DT+ G+ D+L+NN + + T + + + D + Sbjct: 57 -LDVTLTDETSVKNAIDTVIATEGTIDVLVNNAGISMFGVAESATPADVQRMFDVNVIAP 115 Query: 398 LIVEQYLFPLLK--DSGRVINVTNAYGHLS 481 + + P ++ G +INV++ +G S Sbjct: 116 WRLMKLALPAMRKQSEGLIINVSSGWGRFS 145 >UniRef50_A5FCD6 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 265 Score = 43.2 bits (97), Expect = 0.007 Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 1/122 (0%) Frame = +2 Query: 95 LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDKPALKKIADT 274 +G I+ ++++ G + G E F G+ F+ +TD ++ T Sbjct: 22 IGETIINRIADE--GAIPVLVDRNARGFAYAEAFQKRGIDSLFVQTDVTDPVEIENAVKT 79 Query: 275 IQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLFPLLKDS-GRVI 451 I +G D +INN +YEE + + S ++ +Y P LK+S G ++ Sbjct: 80 IVAKYGRIDAVINNVGVNDGAGLDASYEEFMDSLKLNVVSYFLLVKYALPYLKESKGNIL 139 Query: 452 NV 457 N+ Sbjct: 140 NI 141 >UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopirellula marina DSM 3645|Rep: Putative dehydrogenase - Blastopirellula marina DSM 3645 Length = 251 Score = 43.2 bits (97), Expect = 0.007 Identities = 33/139 (23%), Positives = 64/139 (46%), Gaps = 3/139 (2%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A+I G++ +G AI A + V+ A + E+ A ++ + G +A ++D Sbjct: 3 AVITGGSDGIGFAIASAFVAE-GAQVWLVARNAEKLATAADSLQSAGTKVMSTVADLSDP 61 Query: 248 PALKKIADTIQMNHGSFDILINNTEDLKQCEDF--PTYEEAKNVIDSKYKSLLIVEQYLF 421 A +++ + D+L+NN + + F T +E + + S ++ Q L Sbjct: 62 GAAEQVGVEVAATWDRVDVLVNNA-GMARFTSFSEATPDEIQAQVQLNLLSPYLLTQQLL 120 Query: 422 PLLKDS-GRVINVTNAYGH 475 PLL + G VIN+++ H Sbjct: 121 PLLAAAQGNVINISSTSAH 139 >UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rhodobacteraceae|Rep: Short-chain dehydrogenase/reductase SDR - Sagittula stellata E-37 Length = 275 Score = 43.2 bits (97), Expect = 0.007 Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 6/151 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNIL-GLAIVKALSEKL--NGTVYFTASDEEEGLKATENF-NNIGLYPK 220 + +VAI+I I G+ I +A+S L G A D E+ T + + G + Sbjct: 9 LKDRVAIVIGAGAIAEGIGIGRAISMGLAREGAFVVAADDNEDAAARTVDLIRDEGFAAE 68 Query: 221 FLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY-EEAKNVIDSKYKSL 397 + + D +++++ + + HG DIL N K T + + + D+ SL Sbjct: 69 AAVVDVLDDASVERLVEGVADRHGRIDILHCNVGLGKSGPSGQTTPADWRRISDANLTSL 128 Query: 398 LIVEQYLFPLLKDSGR-VINVTNAYGHLSNI 487 + Q + P ++ GR VI VT++ + N+ Sbjct: 129 HVAAQAVLPHMRAQGRGVITVTSSIASIRNV 159 >UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=4; cellular organisms|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 43.2 bits (97), Expect = 0.007 Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M KV I+ G +G I A + K + T E + A E G+ + A Sbjct: 5 MKGKVTIVTGGGKGIGFGIATAFA-KAKSNIVITGRTESTLISAKEKLEKYGVEVLPITA 63 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF--PTYEEAKNVIDSKYKSLLIV 406 + +K+ D I G D+LINN + K T E+ I S ++ Sbjct: 64 DGGYEEQVKEAVDKIIEKFGRIDVLINNAQASKSGLQLVEHTQEDFDLAIKSGIYAVFNF 123 Query: 407 EQYLFPLLKDS-GRVINVTNAYG 472 ++ +P LK++ G VIN + G Sbjct: 124 MKFTYPYLKETKGSVINFASGAG 146 >UniRef50_Q89QA5 Cluster: Oxidoreductase; n=4; Alphaproteobacteria|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 257 Score = 42.7 bits (96), Expect = 0.009 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 4/145 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K A I G +GLA +AL+E V D + A + G + + +T Sbjct: 11 KTAFITGGGQGIGLACAEALAEA-GARVVIGDRDSKVADSAKASLKAKGFDAETAIMDVT 69 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQ--CEDFPTYEEAKNVIDSKYK-SLLIVEQ 412 D + ++A+ + HG DIL+NN + + T E NVID + + Sbjct: 70 DTRRVAEVANDLVARHGKVDILVNNAGIARSETPAETVTDEHWLNVIDVNLNGTFWCCRE 129 Query: 413 YLFPLLK-DSGRVINVTNAYGHLSN 484 + +LK SG ++NV + G + N Sbjct: 130 FGKHMLKAQSGAIVNVGSMSGFIVN 154 >UniRef50_Q6N3Z1 Cluster: Putative oxidoreductase, short-chain dehydrogenase/reductase family precursor; n=1; Rhodopseudomonas palustris|Rep: Putative oxidoreductase, short-chain dehydrogenase/reductase family precursor - Rhodopseudomonas palustris Length = 239 Score = 42.7 bits (96), Expect = 0.009 Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 11/148 (7%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKF--LLAQ 235 K A++ G+ +G AI +AL++ +V A DE E +A N G+ + L Sbjct: 6 KAALVTGGSKGIGFAIAQALAQA-GASVMICARDESEIAQALPALRN-GVRGRVHGLACD 63 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTED--LKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 + D+ ++++ D DIL+NN L E FP E + +D+ Sbjct: 64 VRDEAEVRQLVDHTVTAFDGLDILVNNAGVGLLGPVETFPP-EHWRLTLDTNLTGAFYCC 122 Query: 410 QYLFPLLK--DSGRVINV-----TNAYG 472 Y P LK G ++N+ NAYG Sbjct: 123 HYAIPALKARGGGAIVNIGSRSSVNAYG 150 >UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 251 Score = 42.7 bits (96), Expect = 0.009 Identities = 37/148 (25%), Positives = 67/148 (45%), Gaps = 5/148 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPKFLL 229 + +VA+I + LG A+ AL+ + GT + + DE + G Sbjct: 5 LKDRVAVITGASKGLGKAMAMALAAE--GTRIALVSRDEARLNEVAAELIAAGGDAAIFR 62 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 A +T + +++ I +G DILINN K +F T EE V+D+ + + Sbjct: 63 ADVTSEEQVRQAERAILATYGKVDILINNAGVNVRKPVVEF-TVEEWHRVMDTNVTAAFL 121 Query: 404 VEQYLFPLL--KDSGRVINVTNAYGHLS 481 + + P + + GR++N+T+ H+S Sbjct: 122 MCRSFVPAMSGRGYGRILNMTSIMSHVS 149 >UniRef50_A7IE62 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Xanthobacter sp. (strain Py2) Length = 242 Score = 42.7 bits (96), Expect = 0.009 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 4/140 (2%) Frame = +2 Query: 56 SQKVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + ++ +++G N +GLAI L+ + V D + G A+ GL + + Sbjct: 3 TNEIIALVSGANRGIGLAIAAGLARRKGVNVLLGCRDLDRGKTASLPLLAEGLRVRPVQL 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 TD+ ++ +A I+ +G D L+NN L E + +D L + Sbjct: 63 DATDEASVSSLAHFIENEYGRLDALVNNAGIGLDYDPSLSVVERIQKTLDVNVVGALRLT 122 Query: 410 QYLFPLLKDS--GRVINVTN 463 + + PLL S R++NV++ Sbjct: 123 EAMVPLLAKSTRPRIVNVSS 142 >UniRef50_A4B7Y2 Cluster: 20-beta-hydroxysteroid dehydrogenase; n=1; Alteromonas macleodii 'Deep ecotype'|Rep: 20-beta-hydroxysteroid dehydrogenase - Alteromonas macleodii 'Deep ecotype' Length = 234 Score = 42.7 bits (96), Expect = 0.009 Identities = 37/140 (26%), Positives = 67/140 (47%), Gaps = 3/140 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K ++ G +GL IVK + K V DEE GL+A ++ +G + + Sbjct: 3 KNVLVTGGNRGIGLEIVKGMLSK-GYKVLMGCRDEESGLEAKKD--TVGGDLHIIEMPLD 59 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQC--EDFPTYEEAKNVIDSKYKSLLIVEQY 415 ++ A+ + +G DILINN L ++ AK++ + L +++Q Sbjct: 60 NETAIVDALVRAEAVYGPIDILINNAGVLDDTPWDEVNAETLAKSMQVNVNAPLTLIQQT 119 Query: 416 LFPLL-KDSGRVINVTNAYG 472 L ++ + GR+INV+++YG Sbjct: 120 LPQMIDRGFGRIINVSSSYG 139 >UniRef50_A1UGA4 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 284 Score = 42.7 bits (96), Expect = 0.009 Identities = 41/147 (27%), Positives = 69/147 (46%), Gaps = 3/147 (2%) Frame = +2 Query: 11 SRCVFKAVAFGI*TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATE 190 S+ +A FG+ S K A++ GT +G+ I + L + V ++ + E A + Sbjct: 24 SKFATQAELFGL---SGKRALVTGGTRGIGMMIARGLLQS-GARVVISSRNAEACAHARK 79 Query: 191 NFNNIGLYPKFLLAQITDKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEA 364 + G + A ++ +++AD + G DIL+NN + + E FP +EA Sbjct: 80 ELSVYGDVWA-VPADLSRHDECERLADLVTAESGKLDILVNNAGAMWDEPLETFP--DEA 136 Query: 365 KN-VIDSKYKSLLIVEQYLFPLLKDSG 442 N VID KS + Q L P L+ +G Sbjct: 137 WNTVIDLNLKSPFWLVQALLPALRSAG 163 >UniRef50_A0GP81 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Burkholderiales|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia phytofirmans PsJN Length = 291 Score = 42.7 bits (96), Expect = 0.009 Identities = 35/143 (24%), Positives = 67/143 (46%), Gaps = 6/143 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA+I G+ LGL + +AL E + V TA +E +A + +G+ + ++ + Sbjct: 46 KVALITGGSRGLGLQMAEALGE-MGCRVAITARKADELAEAKTHLQQLGIEVQTVVNDLQ 104 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAK----NVIDSKYKSLLI 403 + + D + HG DIL+NN ED+P K NV + + + Sbjct: 105 RFEGIPGLVDEVLGLHGRIDILVNNAGATWGAPAEDYPDEAWHKVMNLNVNAPFFLAREV 164 Query: 404 VEQYLFPLLKDSGRVINVTNAYG 472 ++ + P + +G+++N+ + G Sbjct: 165 GKRSMIP--RRAGKIVNIASVAG 185 >UniRef50_Q4D5D5 Cluster: Short chain dehydrogenase, putative; n=5; Trypanosomatidae|Rep: Short chain dehydrogenase, putative - Trypanosoma cruzi Length = 298 Score = 42.7 bits (96), Expect = 0.009 Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 5/145 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S++VA++ G +G A V+ +++ L V A D + G A + + +FL Sbjct: 50 LSKRVALVTGGNRGIGYAAVRRMAQ-LGYCVLLAARDVQRGEAAAASLRADDMDVQFLHL 108 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP--TYEEAKNVIDSKYKSLLIV 406 ITD+ ++ A ++ + D LINN + + + + + ++V Sbjct: 109 VITDEASVATAAREVEARYKRLDALINNAAVMDYDNHITPLNVPRMREEFEVNFFAAVMV 168 Query: 407 EQYLFPLL---KDSGRVINVTNAYG 472 PL+ D+ R++NV+ G Sbjct: 169 TNAFLPLMLRTSDAPRIVNVSTPLG 193 >UniRef50_P42317 Cluster: Uncharacterized oxidoreductase yxjF; n=46; Bacteria|Rep: Uncharacterized oxidoreductase yxjF - Bacillus subtilis Length = 257 Score = 42.7 bits (96), Expect = 0.009 Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M ++VA++ + I + + + +V + E KA G + Sbjct: 1 MRKQVALVTGAAGGIRFEIAREFARE-GASVIVSDLRPEACEKAASKLAEEGFDAAAIPY 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 +T + + + IQ +G DIL+NN + + E+FPT + + +I + I Sbjct: 60 DVTKEAQVADTVNVIQKQYGRLDILVNNAGIQHVAPIEEFPT-DTFEQLIKVMLTAPFIA 118 Query: 407 EQYLFPLLKDS--GRVINVTNAYG 472 +++FP++K GR+IN+ + G Sbjct: 119 MKHVFPIMKKQQFGRIINIASVNG 142 >UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4; Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase - Clostridium perfringens (strain SM101 / Type A) Length = 253 Score = 42.3 bits (95), Expect = 0.012 Identities = 43/160 (26%), Positives = 71/160 (44%), Gaps = 14/160 (8%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATE-------NFNNIG 208 ++ KV I+ GT +G A VK + V S +E KA E N++ IG Sbjct: 7 SIKNKVVIVTGGTRGIGFATVKKFLDH-GAKVALCGSRKETVDKALEELNYINPNYDAIG 65 Query: 209 LYPKFLLAQITDKPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDS 382 YP L D +K++ D + G+ DILINN D K + E+ +ID Sbjct: 66 FYPNLL-----DSNEVKEMVDKVLEKWGTIDILINNAGVSDNKSIYT-QSDEDFSKIIDI 119 Query: 383 KYKSLLIVEQYLFPLLKDS--GRVIN---VTNAYGHLSNI 487 K++ + + ++K+ G ++N V + YG + + Sbjct: 120 NVKAIFNCTKAVSEIMKNKKYGVILNTSSVVSLYGQKTGV 159 >UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Ralstonia|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia pickettii 12D Length = 254 Score = 42.3 bits (95), Expect = 0.012 Identities = 28/141 (19%), Positives = 67/141 (47%), Gaps = 3/141 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S + AI+ G+ +G A+ + L+ S +EE ++ G + + A Sbjct: 12 LSGRTAIVTGGSRGIGAAVARRLAADGARVAVVYRSKQEEADAVVQSIRATGAHAIAVQA 71 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVID---SKYKSLLI 403 ++D ++ + T++ G+ DIL+NN L+ + + + A + + + ++L+ Sbjct: 72 DVSDAASVDAMTGTVREAFGAIDILVNNAGILEN-QPVGSIDLASFDVQFRTNAFSTILV 130 Query: 404 VEQYLFPLLKDSGRVINVTNA 466 + L + GR++NV+++ Sbjct: 131 TQAVLPHVPAPGGRIVNVSSS 151 >UniRef50_A6GH96 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Plesiocystis pacifica SIR-1|Rep: Putative short-chain dehydrogenase/reductase - Plesiocystis pacifica SIR-1 Length = 264 Score = 42.3 bits (95), Expect = 0.012 Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 7/147 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K A++ G+ LG I L++ + S E + + + + A + Sbjct: 17 KTALVTGGSRSLGKDIALRLAQAGADVISTYRSQSEAAAEVVDAITRLDRRAVAVQADLE 76 Query: 242 DKPALKKIADTIQMNHGSF-----DILINNTEDLKQCEDFP--TYEEAKNVIDSKYKSLL 400 + +A+ + S+ DIL+NN + + F T +E V+++ +KS++ Sbjct: 77 GTGQIAALAEAVVAQLASWGAEGLDILVNNA-GVSSHQPFGSITEDEFDRVVNTNFKSVV 135 Query: 401 IVEQYLFPLLKDSGRVINVTNAYGHLS 481 + Q L P L D GRVI + + G + Sbjct: 136 FLTQALLPTLNDGGRVIAIGSGLGRFT 162 >UniRef50_A6D9G4 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Vibrio shilonii AK1|Rep: Putative short-chain dehydrogenase/reductase - Vibrio shilonii AK1 Length = 246 Score = 42.3 bits (95), Expect = 0.012 Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 5/150 (3%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 QK+A++ +GLA + L E+ + +D + +F G L + Sbjct: 2 QKIALVTGAYQGIGLATSELLMEQ---GFHVIMADIQSCSALVNDFRQKGYTASHLKLDL 58 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY---EEAKNVIDSKYKSLLIVE 409 +A+ I+ G D+L+NN L P+ + + VI+ ++ Sbjct: 59 AMSSVFPAVANKIEEQFGRLDVLVNNAAILVDLGRHPSLIDEDTYRRVIEVNQIGPFLLT 118 Query: 410 QYLFPLLKDS--GRVINVTNAYGHLSNIKN 493 + L PLLK S R++NV++ G L+ + + Sbjct: 119 RALTPLLKKSSQARIVNVSSQAGQLAQLSD 148 >UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Sphingomonadaceae|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 261 Score = 42.3 bits (95), Expect = 0.012 Identities = 25/88 (28%), Positives = 44/88 (50%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M+ KVAI+ G++ +GLA + L+ + TV A E++ A +G L Sbjct: 5 MTGKVAIVTGGSDGIGLATARLLAAR-GATVVICARREDKLEAARAEIAKVGKVEAVKL- 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN 316 ++D+ A + + + HG D+L+NN Sbjct: 63 DVSDEAAFTALVEDVAARHGRLDMLVNN 90 >UniRef50_A1ZQT0 Cluster: Dehydrogenase/ reductase 1; n=1; Microscilla marina ATCC 23134|Rep: Dehydrogenase/ reductase 1 - Microscilla marina ATCC 23134 Length = 338 Score = 42.3 bits (95), Expect = 0.012 Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDE--EEGLKATENFNNIGLYPKFL 226 M+ KV I T+ G + +++K + E E+ LK +N G + + + Sbjct: 33 MTGKVVAITGTTSGTGFVCAREVAKKGAKVLLLNRQSERAEQALKQLQNEVPNGKF-EAV 91 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 + D +++ DTI+ H D+L+NN + ED T + + + S ++ Sbjct: 92 TCDLQDFDSVRNAIDTIKAKHEVIDVLVNNA-GVMALEDKATKDGYDVQMQTNVISHFLL 150 Query: 407 EQYLFPLLKDS--GRVIN 454 + LFPLLK S RV+N Sbjct: 151 TKELFPLLKKSPEARVVN 168 >UniRef50_A2QKU0 Cluster: Contig An05c0050, complete genome; n=3; Pezizomycotina|Rep: Contig An05c0050, complete genome - Aspergillus niger Length = 274 Score = 42.3 bits (95), Expect = 0.012 Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 5/131 (3%) Frame = +2 Query: 95 LGLAIVKALSEKLNGTVYFTASDEEEGLKATE-NFNNIGLYPKFLLAQITDKPALKKIAD 271 +G AI LS++ G + F + + T+ G + +TD ++K + D Sbjct: 24 IGAAIAMKLSQQ--GAIIFGGNRTLSSAERTKARIEKEGGTCEVQETNVTDSTSVKALVD 81 Query: 272 TIQMNHGSFDILINNTEDLKQCEDFPTYEEA-KNVIDSKYKSLLIVEQYLFPLL---KDS 439 + HG DILINN + EE +D KS+ + ++ P++ + Sbjct: 82 SCMQRHGRIDILINNVGKSEPGGPAELSEETWDQQVDLNLKSVYLTSHFVLPIMEKQETG 141 Query: 440 GRVINVTNAYG 472 G VINV++ G Sbjct: 142 GTVINVSSIAG 152 >UniRef50_Q4J702 Cluster: Oxidoreductase; n=2; Sulfolobus|Rep: Oxidoreductase - Sulfolobus acidocaldarius Length = 264 Score = 42.3 bits (95), Expect = 0.012 Identities = 29/127 (22%), Positives = 67/127 (52%), Gaps = 2/127 (1%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A+++ ++ +G AI + SE + G V + DEE + +++ + G + ITD Sbjct: 14 AVVLGASSGIGKAIAEMFSE-MGGKVVLSDIDEEGLKRLSDSLRSRGHEVNHMKCDITDL 72 Query: 248 PALKKIADTIQMNHGSFDIL-INNTEDLKQCEDFPTYEEAKNVIDSKYK-SLLIVEQYLF 421 +KK+ + +G+ D L + + ++++ + TYE+ + VI+ K + ++V+++L Sbjct: 73 NQVKKLVNFSLSVYGNVDALYVTPSINVRKSIENYTYEDFEKVINVNLKGNFMVVKEFLS 132 Query: 422 PLLKDSG 442 + + G Sbjct: 133 VMKNNKG 139 >UniRef50_P40580 Cluster: Uncharacterized oxidoreductase YIR036C; n=9; Saccharomycetales|Rep: Uncharacterized oxidoreductase YIR036C - Saccharomyces cerevisiae (Baker's yeast) Length = 263 Score = 42.3 bits (95), Expect = 0.012 Identities = 29/138 (21%), Positives = 64/138 (46%), Gaps = 6/138 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KV +I + +GL +VK + E+ + + + + E GL++ + + + + IT Sbjct: 3 KVILITGASRGIGLQLVKTVIEEDDECIVYGVARTEAGLQSLQREYGADKFV-YRVLDIT 61 Query: 242 DKPALKKIADTIQMNHGSFDILINN------TEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 D+ ++ + + I+ HG D ++ N + + Q ++ + + D + S++ Sbjct: 62 DRSRMEALVEEIRQKHGKLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNFFSIVS 121 Query: 404 VEQYLFPLLKDSGRVINV 457 + PLLK S V N+ Sbjct: 122 LVALCLPLLKSSPFVGNI 139 >UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=3; Gammaproteobacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Buchnera aphidicola subsp. Baizongia pistaciae Length = 245 Score = 42.3 bits (95), Expect = 0.012 Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENF-NNIGLYPKFLLA 232 ++K+A+I LG I + LS N TV T S ++G K + N G+ K Sbjct: 4 TKKIAVITGANRGLGKGIAEELSNTNNITVIGT-STSQKGCKIINKYLKNNGIGIKL--- 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIV 406 IT+ + K D + N G DILINN + K + T ++ +V++ S+ + Sbjct: 60 DITNPNEITKTMDFVYKNFGRVDILINNAGIIRDKLLINMKT-QDWNSVLNVNLNSIFYM 118 Query: 407 EQYLF-PLLKD-SGRVINVTNAYGHLSN 484 + + ++K+ G++I + + H+ N Sbjct: 119 SKSVIRNMIKNKQGKIITIGSVIAHIGN 146 >UniRef50_Q9KCQ9 Cluster: Oxidoreductase; n=10; Firmicutes|Rep: Oxidoreductase - Bacillus halodurans Length = 243 Score = 41.9 bits (94), Expect = 0.016 Identities = 32/144 (22%), Positives = 61/144 (42%), Gaps = 1/144 (0%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M++++ ++ +G I A + V + ++G +A E G +F+ Sbjct: 1 MTKRIVLVTGAAQGIGTEIAAAFAAA-GDRVILADVNVDKGHEAAERITQNG-EARFIHC 58 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA-KNVIDSKYKSLLIVE 409 + + + + I+ GS D+LINN F EEA VI + +S+ Sbjct: 59 DVKNISEINHLFAQIRGEEGSLDVLINNAGISIWKNLFDVTEEAWDEVIHTNVRSVFFCS 118 Query: 410 QYLFPLLKDSGRVINVTNAYGHLS 481 Q L+K+ G +IN+ + +S Sbjct: 119 QQAARLMKEGGAIINIASTRAFMS 142 >UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 246 Score = 41.9 bits (94), Expect = 0.016 Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 3/144 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K AI+ + +G A L+ V A ++E+ K +G+ + A + Sbjct: 5 KTAIVTGASRGIGRATAMELARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQADVA 64 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKN-VIDSKYKSLLIVEQYL 418 D +++ + G+ DIL+NN + EE + VID+ K + + + Sbjct: 65 DSESVQAMVKETIDTFGAVDILVNNAGITRDNLFMRMKEEDWDAVIDTNLKGVFHCSKAV 124 Query: 419 F-PLLKDS-GRVINVTNAYGHLSN 484 P++K GR+INV++ G + N Sbjct: 125 TRPMMKQRFGRIINVSSVVGAIGN 148 >UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Alr4456 protein - Anabaena sp. (strain PCC 7120) Length = 267 Score = 41.9 bits (94), Expect = 0.016 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 4/148 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 T++ + A+I T +GLAI + L V A + E + + +++ G + Sbjct: 19 TLAGRKALITGATKGIGLAIAQEFLA-LGAEVVIVARNAEAIEQQMKAWHSAGKVHG-VA 76 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 A ++ + + D + G DIL+NN T K+ D+ T EE + S+ Sbjct: 77 ADVSTSEGRQMMLDYVSKTFGELDILVNNVGTNIRKKATDY-TEEEFAAIFQINLTSIFE 135 Query: 404 VEQYLFPLLKDS--GRVINVTNAYGHLS 481 + + +PLLK S ++N+ + G +S Sbjct: 136 LSRLFYPLLKTSKNSSIVNIGSVAGLIS 163 >UniRef50_Q03B39 Cluster: Carbonyl reductase; n=2; Bacilli|Rep: Carbonyl reductase - Lactobacillus casei (strain ATCC 334) Length = 244 Score = 41.9 bits (94), Expect = 0.016 Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 5/145 (3%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 Q + +I +G AL ++ + A ++ G +A + G+ + ++ + Sbjct: 5 QTLTLITGADKGIGFETAMALGKR-GQHLLVGARNQARGEQAINKLHTAGVSAELVILDV 63 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNV---IDSKYKSLLIVE 409 T + A I+ +HG ++LINN P+ + D + L+ V Sbjct: 64 TQAGTIATAAKQIEASHGYLNVLINNAGIALDAHQPPSQLPVMTMRQDFDVNFFGLVSVT 123 Query: 410 QYLFPLLKDS--GRVINVTNAYGHL 478 Q + PLLK ++INV++ G L Sbjct: 124 QAMIPLLKKGAPAKIINVSSNMGSL 148 >UniRef50_A3EPN7 Cluster: Putative short-chain alcohol dehydrogenase; n=1; Leptospirillum sp. Group II UBA|Rep: Putative short-chain alcohol dehydrogenase - Leptospirillum sp. Group II UBA Length = 235 Score = 41.9 bits (94), Expect = 0.016 Identities = 31/144 (21%), Positives = 70/144 (48%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M +K ++ T+ +GLAI + ++ + T+ T + + ENF +G + + A Sbjct: 1 MQKKTVLVTGSTSGIGLAIAREMAREGFRTI-LTGRRKALLRETVENFLRLGHEVRGIPA 59 Query: 233 QITDKPALKKI-ADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIV 406 + + +++ A+T+ G D+L+NN +Q D T E+ ++++ ++ I+ Sbjct: 60 DLAEPGEAERLFAETLDWTGGRLDVLVNNAGTWQQSPVDEITREDFRSLMSLNLEAPFIL 119 Query: 407 EQYLFPLLK--DSGRVINVTNAYG 472 +K SG ++N+++ G Sbjct: 120 SGLAMRTMKRQRSGTIVNISSVAG 143 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 41.9 bits (94), Expect = 0.016 Identities = 36/148 (24%), Positives = 72/148 (48%), Gaps = 7/148 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA++ + +G AI + L+E+ G + E G +A ++ +G K + +T Sbjct: 6 KVALVTGASRGIGKAIAELLAER--GAKVIGTATSESGAQAISDY--LGDNGKGMALNVT 61 Query: 242 DKPALKKIADTIQMNHGSFDILINN---TED--LKQCEDFPTYEEAKNVIDSKYKSLLIV 406 + +++ + I G DIL+NN T D L + ++ EE +++++ S+ + Sbjct: 62 NPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKE----EEWSDIMETNLTSIFRL 117 Query: 407 EQYLF--PLLKDSGRVINVTNAYGHLSN 484 + + + K GR+INV + G + N Sbjct: 118 SKAVLRGMMKKRQGRIINVGSVVGTMGN 145 >UniRef50_UPI0000D5685B Cluster: PREDICTED: similar to CG31235-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG31235-PA - Tribolium castaneum Length = 345 Score = 41.5 bits (93), Expect = 0.021 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 4/143 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFL--LAQ 235 K+ II G++ +GL K L++K + + E G +A E + + L Sbjct: 48 KIVIITGGSSGIGLTTAKELAKK-GARIILAVRNAERGKRALEYLLRECPEAEAIIKLVD 106 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 + D ++++ A+ I + + DILINN + T + + I + Y ++ Sbjct: 107 LNDFVSIREFANQINLEYERVDILINNAGIIFH-PFRKTVDGNEMTISTNYFGPFLLTHL 165 Query: 416 LFPLL--KDSGRVINVTNAYGHL 478 L LL D+GRVIN+ +A HL Sbjct: 166 LLNLLSKSDNGRVINL-SAVAHL 187 >UniRef50_A3K7W9 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Sagittula stellata E-37|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Sagittula stellata E-37 Length = 254 Score = 41.5 bits (93), Expect = 0.021 Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 2/133 (1%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A++ GT+ +GLAI +A E V T E G +A G F+ + Sbjct: 12 AVVTGGTSGIGLAIARAFLEA-GVEVIITGRSEARGAEALAALTPHGTV-HFVAGDAGSE 69 Query: 248 PALKKIADTIQMNHGSFDILI--NNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 ++ + G FD L+ T ED T ++ + VID+ S+ + + L+ Sbjct: 70 DGAARLEMAVTDLLGGFDTLVCAAGTNRRMPPEDL-TLDDWEAVIDTNLTSVFLTCRALY 128 Query: 422 PLLKDSGRVINVT 460 PLLK+SG VT Sbjct: 129 PLLKESGEGCIVT 141 >UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 250 Score = 41.5 bits (93), Expect = 0.021 Identities = 23/88 (26%), Positives = 41/88 (46%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ K+A+I N +G A + S + TV D+E+GL+ + G F+ Sbjct: 3 LAGKIALITGAANGMGCATAETFSRQ-GATVVIADVDDEDGLQVAKQIGTSGGTAHFVHL 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN 316 +TD+ A + + + DIL+NN Sbjct: 62 DVTDETAWACAVEDVLGRYERLDILVNN 89 >UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase family protein; n=14; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 295 Score = 41.5 bits (93), Expect = 0.021 Identities = 38/165 (23%), Positives = 77/165 (46%), Gaps = 4/165 (2%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQ 235 S K+ +I ++ +G +I L+++ N VY T+ ++E + NF + Sbjct: 29 SDKIVLITGASSGIGKSIATYLAKR-NFKVYGTSRSKKESSDSVFNFVQL---------D 78 Query: 236 ITDKPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +T++ ++ + I G D+LINN E+ P E K ++ Y L + Sbjct: 79 VTNEQSIIAAINEISKKEGRIDVLINNAGVGITGPIEETPE-SEIKKAFETNYFGPLNMI 137 Query: 410 QYLFPLLK--DSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVE 538 + + P+++ + G +INVT+ G++ + T +A ++T E Sbjct: 138 KNVLPVMRKNNGGLIINVTSIAGYMGLPYRGIYSATKSALEITAE 182 >UniRef50_Q9XVS9 Cluster: Putative uncharacterized protein dhs-22; n=2; Caenorhabditis|Rep: Putative uncharacterized protein dhs-22 - Caenorhabditis elegans Length = 333 Score = 41.5 bits (93), Expect = 0.021 Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 6/169 (3%) Frame = +2 Query: 2 IFISRCVFKAVAFGI*TMSQKVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGL 178 +F +R FK F ++ + ++ G+N +G V+ L+ + VY EE+ Sbjct: 26 LFFTRRYFKGGQFNERVSAKGLVAVVTGSNCGIGFETVRELNLR-KADVYMLCRSEEKAN 84 Query: 179 KATENFNNIGLYPK---FLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP 349 +A G F+ +TD ++++ A + + DILINN + Q + Sbjct: 85 EAKRMLVRQGCDATRLHFIECDLTDFESVRRAAKETLESTDTIDILINNAGIMFQSKHEQ 144 Query: 350 TYEEAKNVIDSKYKSLLIVEQYLFPLLKDS--GRVINVTNAYGHLSNIK 490 T + + S + ++ + P +K S R+INV++ HL + K Sbjct: 145 TKDGHEKTWQSNHLGPFLLTELFLPAVKKSSYARIINVSSRI-HLKSEK 192 >UniRef50_UPI000049A4BD Cluster: short chain dehydrogenase family protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: short chain dehydrogenase family protein - Entamoeba histolytica HM-1:IMSS Length = 311 Score = 41.1 bits (92), Expect = 0.027 Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 3/149 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S KV +I GT+ +G IV+ L++ T+ + + E K E ++ + Sbjct: 35 LSGKVVVITGGTHGMGKVIVEQLADT-GATIISCSRNNEIAQKVIEEIKSVHKSCNIIHE 93 Query: 233 QI--TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKS-LLI 403 + +D ++K+ A+ I + DILINN + + T + + + Y L+ Sbjct: 94 HLDLSDLDSVKQCAENILNKYHEIDILINNA-GVMRVPYGKTKQGYETQMGVNYLGHFLL 152 Query: 404 VEQYLFPLLKDSGRVINVTNAYGHLSNIK 490 ++ L L K +GRVIN ++ L + K Sbjct: 153 TQKLLSALEKCNGRVINYSSVASKLYHRK 181 >UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Streptomyces sp. Tu6071 Length = 244 Score = 41.1 bits (92), Expect = 0.027 Identities = 21/83 (25%), Positives = 40/83 (48%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A++ GT+ +GLA A + + V T DE+ G + + G F+ A++ + Sbjct: 6 ALVTGGTSGIGLATAMAFAGR-GADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAELRGE 64 Query: 248 PALKKIADTIQMNHGSFDILINN 316 + +++A G D+L+NN Sbjct: 65 SSARRLAQAAVARFGRIDVLVNN 87 >UniRef50_Q1V1U2 Cluster: FabG-like protein; n=2; Candidatus Pelagibacter ubique|Rep: FabG-like protein - Candidatus Pelagibacter ubique HTCC1002 Length = 259 Score = 41.1 bits (92), Expect = 0.027 Identities = 38/144 (26%), Positives = 65/144 (45%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATEN-FNNIGLYPKFLL 229 + +K A++ G LG I AL+ N V T+ ++++ K +++ NI Y Sbjct: 5 LKRKTALVTGGATGLGKGIAIALANS-NAKVVVTSRNKKDIEKISKHPSGNIFGYN---- 59 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCED-FPTYEEAKNVIDSKYKSLLIV 406 IT+ L+ + I+ + DILINN +D F K V+D + + + V Sbjct: 60 LDITNSSELETLYKNIKKKYQKIDILINNVGHTLDIKDPFTNINNWKKVMDLNFFTAVNV 119 Query: 407 EQYLFPLLKDS--GRVINVTNAYG 472 +K GR+IN+T+ G Sbjct: 120 NNMFINDMKKKNWGRIINITSIAG 143 >UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesiocystis pacifica SIR-1|Rep: Short chain dehydrogenase - Plesiocystis pacifica SIR-1 Length = 271 Score = 41.1 bits (92), Expect = 0.027 Identities = 31/143 (21%), Positives = 61/143 (42%), Gaps = 4/143 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KV I G +G A+ +A + K + D E + E G ++ Sbjct: 7 KVIAITGGAGGIGAALARAFAAK-GAHLALLDLDAEAAERTAEGLRQGGARCSAHAVDVS 65 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP--TYEEAKNVIDSKYKSLLIVEQY 415 D+ AL++ D + HG D+LINN L F + EE ++D ++++ + Sbjct: 66 DRGALERGRDEVLREHGGVDVLINNA-GLTVFSTFEELSQEEIDRILDVNLRAVIDGCKL 124 Query: 416 LFPLLKD--SGRVINVTNAYGHL 478 P L++ ++N+ ++ ++ Sbjct: 125 FMPALRERPEAHIVNIASSASYV 147 >UniRef50_A4BUN6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nitrococcus mobilis Nb-231|Rep: Short-chain dehydrogenase/reductase SDR - Nitrococcus mobilis Nb-231 Length = 243 Score = 41.1 bits (92), Expect = 0.027 Identities = 34/159 (21%), Positives = 70/159 (44%), Gaps = 13/159 (8%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 T ++++A+I LG + L+ + V T+ D +G A + L + Sbjct: 2 TENRRIAVITGANRGLGFETARQLARRGYKAV-LTSRDAVQGKAAADKLQGEALDVGYHP 60 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSL---- 397 +T +++++A + G D+L+NN + A NV + +SL Sbjct: 61 LDVTRADSVQRLAGFLDNAFGRLDVLVNNAGIFPEQASAHGAHSAPNVFEMPLESLHENL 120 Query: 398 -------LIVEQYLFPLLK--DSGRVINVTNAYGHLSNI 487 L + Q + PL++ GR++N+++ YG L+++ Sbjct: 121 QTNAFGALRLIQTIVPLMRRHGYGRIVNISSGYGQLAHM 159 >UniRef50_A0G5F7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Burkholderia phymatum STM815|Rep: Short-chain dehydrogenase/reductase SDR precursor - Burkholderia phymatum STM815 Length = 261 Score = 41.1 bits (92), Expect = 0.027 Identities = 35/162 (21%), Positives = 67/162 (41%), Gaps = 5/162 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFN-NIGLYPKFL 226 T+ K A++ +N LGLA+ +AL+ V ++ + T+ + + ++ Sbjct: 2 TLKGKGALVTGSSNGLGLAMARALAGAGCDIVLHGLETPQQMARTTDELAASFDVNVAYV 61 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLL 400 + + + + D Q + D+LINN E FP E N + + Sbjct: 62 QSDLASAAGVDALIDNAQARMKTLDVLINNAVVRHFAGLESFPL-EHWNNALAVNLTAAF 120 Query: 401 IVEQYLFPLLKDSG--RVINVTNAYGHLSNIKNDKWIKTLTA 520 Q P +++ G R+ N+T+ YG + ++ T TA Sbjct: 121 RAIQLTLPGMRERGWGRIFNMTSVYGARAIANRVDYVTTKTA 162 >UniRef50_A7RWI1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 560 Score = 41.1 bits (92), Expect = 0.027 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 6/144 (4%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNI----GLYPKF 223 +Q VA++ LG IV+AL V + E+ K + N++ + K Sbjct: 318 NQHVALVTGAAKRLGAGIVRALHGSGFRVVIHYNNSGEDAEKIVQEMNSVRSDSAIMLKA 377 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSL-L 400 L+ + A K I DT+ G D+L+NN E EE N + S Sbjct: 378 DLSTNIQETARKLIEDTVTA-FGQLDLLVNNASQFCPTESGSVQEETWNKLMGVNLSFPF 436 Query: 401 IVEQYLFPLLKDS-GRVINVTNAY 469 + Q FP LK S G +IN+ + + Sbjct: 437 FLSQAAFPHLKRSHGSIINMIDIH 460 >UniRef50_Q0V189 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 260 Score = 41.1 bits (92), Expect = 0.027 Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 7/153 (4%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALS-EKLNGTVYFTA---SDEEEGLKATENFNNIGLYPKFL 226 +++ +I TN +GL L+ + N V A S E +K + + G L Sbjct: 6 KQIILITGATNGIGLDTTVYLARDSPNNHVIMGARSSSKAEARIKEVQGKDIKGTLSYVL 65 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 L Q D ++ + I+ G D+L+NN L +++ E + ++ +++ Sbjct: 66 LDQNEDA-SISSAVEQIKKEFGRVDVLVNNAGVCLPDDKEWAPRETLRATFETNVFGVML 124 Query: 404 VEQYLFPLLKDS--GRVINVTNAYGHLSNIKND 496 + + L PLLK S +VINVT+ G ++ + D Sbjct: 125 LTEALIPLLKASKNPKVINVTSGLGSITGLSPD 157 >UniRef50_UPI00015B6097 Cluster: PREDICTED: similar to CG11200-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG11200-PA - Nasonia vitripennis Length = 350 Score = 40.7 bits (91), Expect = 0.036 Identities = 41/158 (25%), Positives = 69/158 (43%), Gaps = 13/158 (8%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M +VAI+ G+ +G +V+ L + + V G KA E+ G+ Sbjct: 63 MPGRVAIVTGGSRGIGTEVVRMLLQS-DVEVVIACRRTSAGEKAVESIRKCGVTSGKANV 121 Query: 233 QITDKPAL---KKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSK----YK 391 D +L +K + + N+ DIL+NN + F Y E K+ + + Y Sbjct: 122 MELDNSSLDSVRKFVEEFKNNYQKLDILVNNAGIM-----FTPYGETKDGFEEQYGVNYL 176 Query: 392 SLLIVEQYLFPLLKDSG------RVINVTNAYGHLSNI 487 S ++ L PLLK++G RV+NV++ L +I Sbjct: 177 SHFLLTVLLIPLLKNAGTADCFARVVNVSSCAHLLGDI 214 >UniRef50_Q88ZF7 Cluster: Short-chain dehydrogenase/oxidoreductase; n=2; Bacteria|Rep: Short-chain dehydrogenase/oxidoreductase - Lactobacillus plantarum Length = 299 Score = 40.7 bits (91), Expect = 0.036 Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 4/146 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 MSQ I+I G + G+ AL + G + + A+ E K T+ G++ L Sbjct: 1 MSQPRVILITGASS-GIGKATALKLQAQGNIVYGAARRIE--KMTD-LAAAGVH--VLKV 54 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 +TD+ L TIQ+ G D+LINN ED P E + ++ + Sbjct: 55 DVTDEATLIAAVKTIQVEQGRIDVLINNAGYGSYGSLEDVPV-AEGEYQFKVNVFGVMRL 113 Query: 407 EQYLFPLLK--DSGRVINVTNAYGHL 478 Q + PL++ GR+I+V++ G + Sbjct: 114 TQLVLPLMRAQHRGRIIDVSSIGGKI 139 >UniRef50_Q46NA6 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 254 Score = 40.7 bits (91), Expect = 0.036 Identities = 30/143 (20%), Positives = 62/143 (43%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ +VA++ G G I KAL+ G + G A + N IG + +A Sbjct: 10 LTGQVAVVTGG----GSGIGKALAHTFAGAGARVVVLDTNGAAAEQVANEIGSMAQHAVA 65 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP-TYEEAKNVIDSKYKSLLIVE 409 ++++ A++ + + + HG D+L NN ++ F T + V+ + + Sbjct: 66 DVSNENAIESVMEDVARQHGRIDVLFNNAGINRRNTSFDLTIADWNAVVTVNMTGMFLCA 125 Query: 410 QYLFPLLKD--SGRVINVTNAYG 472 + ++D GR++N + G Sbjct: 126 RAAARHMRDGGGGRIVNTASILG 148 >UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 249 Score = 40.7 bits (91), Expect = 0.036 Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 4/141 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KV I+ G+ +G A K ++E+ V ++EEG KA GL + Sbjct: 4 LTGKVGIVTGGSKGIGFATAKRIAEE-GAKVVIANRNKEEGEKAALQLREKGLEVYSIPC 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILIN--NTEDLKQCEDFPTYEEAKNVIDSKYKSLLI- 403 + +KK+ + +G DIL+N K E++ T E+ ++D K Sbjct: 63 DVGKVADIKKLVSEVYGRYGRIDILVNCAGVNVRKPIEEY-TEEDWNYMVDINLKGTFFA 121 Query: 404 -VEQYLFPLLKDSGRVINVTN 463 +E + + G ++N+ + Sbjct: 122 CIEAGKHMIAQKEGVIVNLAS 142 >UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase precursor; n=2; Clostridium difficile|Rep: Probable short chain dehydrogenase precursor - Clostridium difficile (strain 630) Length = 245 Score = 40.7 bits (91), Expect = 0.036 Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 6/146 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALS-EKLNGTVYFTASDEE-EGLKATENFNNIGLYPKFL 226 M +K +I G +G A+ KA + E N V F S+ E + L N N + K Sbjct: 1 MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEKNFSV--KLF 58 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP--TYEEAKNVIDSKYKSLL 400 A I+++ ++ + D G D+L+NN + Q + F T E+ N+++ K Sbjct: 59 KANISNREDVEDMVDYCIKEFGGLDVLVNNA-GVSQDKLFTDITDEDWDNMMNINLKGSF 117 Query: 401 IVEQYL--FPLLKDSGRVINVTNAYG 472 Q + + + G +IN+++ +G Sbjct: 118 YCSQVALKYMISEKKGNIINISSIWG 143 >UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Flavobacteriales bacterium HTCC2170 Length = 245 Score = 40.7 bits (91), Expect = 0.036 Identities = 33/157 (21%), Positives = 66/157 (42%), Gaps = 4/157 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + K+A++ G +G A+ + +++ G +G E G ++ Sbjct: 3 LKDKIAVVTGGARGIGQAVSELFAKE--GATVIIMDLLPQGQAVAEGIIASGGKAEYHSL 60 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAK--NVIDSKYKSLLIV 406 +T+K ++ + ++ +G DILINN + + EA+ VI+ K + I Sbjct: 61 SVTNKSDVEGVFSSVNDKYGKIDILINNA-GITRDRTLEKMSEAEWDAVIEVNLKGVFIC 119 Query: 407 EQYLFPLLKDS--GRVINVTNAYGHLSNIKNDKWIKT 511 Q + P +K S GR+++ + G N + T Sbjct: 120 TQAVVPYMKASKYGRIVSAASNVGLRGNFGQTNYAAT 156 >UniRef50_Q9SY73 Cluster: F14N23.19; n=5; Magnoliophyta|Rep: F14N23.19 - Arabidopsis thaliana (Mouse-ear cress) Length = 242 Score = 40.7 bits (91), Expect = 0.036 Identities = 31/138 (22%), Positives = 64/138 (46%), Gaps = 4/138 (2%) Frame = +2 Query: 71 IIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDKP 250 ++I G + GL AL G + +E L A ++ + L A + Sbjct: 20 VLITGVS-KGLGRALALELAKRGHTVIGCARSQEKLTALQSELSSSTNHLLLTADVKSNS 78 Query: 251 ALKKIADTIQMNHGSFDILINNTEDLKQCEDF--PTYEEAKNVIDSKYKSLLIVEQYLFP 424 +++++A TI G DI++NN + + + E+ NV+D+ K + V ++ P Sbjct: 79 SVEEMAHTIVEKKGVPDIIVNNAGTINKNSKIWEVSAEDFDNVMDTNVKGVANVLRHFIP 138 Query: 425 LL--KDSGRVINVTNAYG 472 L+ + G ++N+++ +G Sbjct: 139 LMLPRKQGIIVNMSSGWG 156 >UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p - Drosophila melanogaster (Fruit fly) Length = 255 Score = 40.7 bits (91), Expect = 0.036 Identities = 36/143 (25%), Positives = 69/143 (48%), Gaps = 2/143 (1%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++S KV I+ ++ +G AI + L+ + G L+AT+ G + ++ Sbjct: 6 SLSNKVVIVTGASSGIGAAIAQVLARE--GATLALVGRNVANLEATKKSLK-GTQAEIVV 62 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPT-YEEAKNVIDSKYKSLLIV 406 A +T K A + T+ G D+L+NN L + EE V+++ + ++++ Sbjct: 63 ADVT-KDADAIVQQTLA-KFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILL 120 Query: 407 EQYLFP-LLKDSGRVINVTNAYG 472 + + P LLK G V+NV++ G Sbjct: 121 TKAVLPHLLKTKGAVVNVSSCAG 143 >UniRef50_Q6BVQ9 Cluster: Debaryomyces hansenii chromosome C of strain CBS767 of Debaryomyces hansenii; n=1; Debaryomyces hansenii|Rep: Debaryomyces hansenii chromosome C of strain CBS767 of Debaryomyces hansenii - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 258 Score = 40.7 bits (91), Expect = 0.036 Identities = 36/147 (24%), Positives = 61/147 (41%), Gaps = 7/147 (4%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEK-LNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQ 235 ++ A+I G +G AI K L++ LN + + + +K + N G F Sbjct: 2 RRTALITGGARGIGEAISKRLAKDGLNVVICDLQNQNKAAMKTIQEINQFGGNAVFYPLD 61 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP--TYEEAKNVIDSKYKSLLIVE 409 + K ++K D G+FD+++NN + F T +E + K +L Sbjct: 62 VRVKSQIEKTIDNAYEKFGTFDVMVNNA-GICLVNSFADITEDELEKQWAVNVKGVLFGM 120 Query: 410 QYLFPLLKD----SGRVINVTNAYGHL 478 Q KD +GR+IN + G L Sbjct: 121 QAAARKFKDVQNRTGRIINAASISGQL 147 >UniRef50_Q4WZ51 Cluster: Short chain dehydrogenase family protein, putative; n=3; Pezizomycotina|Rep: Short chain dehydrogenase family protein, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 243 Score = 40.7 bits (91), Expect = 0.036 Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 1/128 (0%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 MS+ + +I +G A + LS K + V + + E G + G L Sbjct: 1 MSRPLVLITGANQGVGRATAQILSTKHDYHVIVGSRNHEAGEAVAADIRKGGHQATSLQL 60 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIVE 409 +T + ++K TI+ + G D+LINN L E +E + ++ Sbjct: 61 DLTSENSIKAAVSTIERHFGYLDVLINNAGILIDGEKSLAPWEIYSRTFTTNVIGTGVLT 120 Query: 410 QYLFPLLK 433 +YL PLL+ Sbjct: 121 EYLVPLLR 128 >UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 313 Score = 40.7 bits (91), Expect = 0.036 Identities = 32/140 (22%), Positives = 64/140 (45%), Gaps = 3/140 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA+I +G AI +AL+ K V + ++ +K E G +T Sbjct: 33 KVALITGAGQGIGAAIAEALA-KSGANVAILDLNTDKLVKTKEACLQHGGKVADFACDVT 91 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIVEQYL 418 ++ +K++ D ++ G D+L+NN Q T++ I+ +K+ L++ + Sbjct: 92 NEHKIKEVIDAVEKQLGPIDVLVNNAGIFDQRPFIMSTFDGFWRQIEVNFKAPLMLIHQM 151 Query: 419 FPLLKD--SGRVINVTNAYG 472 P +++ G +IN+ + G Sbjct: 152 LPRMRERGGGCIINIASRSG 171 >UniRef50_Q0CF34 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 258 Score = 40.7 bits (91), Expect = 0.036 Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 9/149 (6%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPK--- 220 M KVAI+ G+ +G I L+ NG V T S + T IG Sbjct: 9 MEGKVAIVTGGSRGIGEQIALELAR--NGVKVSITYSSPRSEARLTALIQTIGALGNGSS 66 Query: 221 --FLLAQITDKPALKKI-ADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSK 385 + A + D + +I A+T+Q DIL+NN E +K +D T + V D Sbjct: 67 AIAIKADLRDPQSPSRIVAETVQHFGEHIDILVNNAGVELVKPMQDV-TVTDFHFVYDLN 125 Query: 386 YKSLLIVEQYLFPLLKDSGRVINVTNAYG 472 ++ +++ Q + P L+ GR+IN+ + G Sbjct: 126 VRAPMLMMQAVLPHLRAPGRIINIGSVGG 154 >UniRef50_A2R3R8 Cluster: Contig An14c0180, complete genome; n=3; Pezizomycotina|Rep: Contig An14c0180, complete genome - Aspergillus niger Length = 249 Score = 40.7 bits (91), Expect = 0.036 Identities = 35/146 (23%), Positives = 64/146 (43%), Gaps = 5/146 (3%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNI-GLYPKFLLAQ 235 QK+ +I +G K L N V + D +G +A + + G+ Q Sbjct: 5 QKLVLITGANQGIGFETAKNLILSDNYHVILGSRDPAKGEEAAKTLEAVPGIKGSVSSIQ 64 Query: 236 I--TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 I TD ++ A I+ +G DIL+NN + + P+ E + ++D L Sbjct: 65 IDVTDDQSVDNAAAQIKAQYGRLDILVNNAA-MSSMKHPPSREAMRQILDVNVVGALSTT 123 Query: 410 QYLFPLLKDSG--RVINVTNAYGHLS 481 + LL++S R++ V+++ G +S Sbjct: 124 EAFLDLLRNSSEKRLVFVSSSTGSIS 149 >UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1; Cenarchaeum symbiosum|Rep: Short-chain alcohol dehydrogenase - Cenarchaeum symbiosum Length = 252 Score = 40.7 bits (91), Expect = 0.036 Identities = 29/132 (21%), Positives = 59/132 (44%), Gaps = 2/132 (1%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA++ ++ +G +IV+ L+E+ G + L+A + + +T Sbjct: 6 KVAVVTGASSDIGASIVRRLAEE--GAKVVLLGRRPDALEAARRVSGHEESTASIPCDVT 63 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYE--EAKNVIDSKYKSLLIVEQY 415 D+ L ++AD + +G DIL+N + + F + K +I +L+ + Sbjct: 64 DEGQLAQMADRVVEAYGRIDILVNGAGSIHDPKHFHVMPIMDVKKMIHGNVLGVLLPTRA 123 Query: 416 LFPLLKDSGRVI 451 + + D+G VI Sbjct: 124 VLGKMMDTGGVI 135 >UniRef50_Q39VG0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Geobacter|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 248 Score = 40.3 bits (90), Expect = 0.047 Identities = 42/155 (27%), Positives = 68/155 (43%), Gaps = 2/155 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M + A+I+ N +G AI + KL V +D +E K + G + + Sbjct: 1 MKDRTALIVGAANDIGGAISVRFA-KLGARVVLIDTDRQELDKVSALVAAAGGEAEVIAV 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQ 412 D A+K D I HGS DIL+N + + P E +++ +SL ++ Sbjct: 60 DGADSGAVKSTIDGIAGKHGSIDILVN---AIDHRDGVPITE---GTVETWERSL---KE 110 Query: 413 YLFPLLKDSGRVINV--TNAYGHLSNIKNDKWIKT 511 + PL+ S VI V N YG + NI + ++ T Sbjct: 111 NITPLVSFSLNVIPVMKNNKYGRIVNIGSLDYLGT 145 >UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 254 Score = 40.3 bits (90), Expect = 0.047 Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 6/153 (3%) Frame = +2 Query: 32 VAFGI*TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKAT-ENFNNIG 208 ++ I + KVAI+ G+ G AI L++ G AS + L A E +G Sbjct: 1 MSLDIFNLEGKVAIVTGGSRGFGKAIALGLAQA--GADVVVASRTQADLDAVAEEIRALG 58 Query: 209 LYPKFLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP-TYEEAKNVIDSK 385 + + D+ +++ +A G DIL+NN T E+ ++D Sbjct: 59 RKSLAVATDMLDRGSIENLAAKTMEAFGKIDILVNNAGQGWTVPFLKWTDEQWDQILDVN 118 Query: 386 YKSLL----IVEQYLFPLLKDSGRVINVTNAYG 472 K IV Q++F +GRVIN+++A G Sbjct: 119 LKGYFLCTQIVGQHMFK--AKAGRVINISSAMG 149 >UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR precursor - Clostridium phytofermentans ISDg Length = 258 Score = 40.3 bits (90), Expect = 0.047 Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 3/155 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVA++ ++ LG A + K V A E+ + IG + Sbjct: 7 LTGKVAVVTGASSGLGADAALAYA-KAGADVALLARRIEKLNEVKAEIEKIGRKVVAVGC 65 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +T++ ++K T+ G DIL+NN ++ D + E+ D+ K + + Sbjct: 66 DVTNEESVKTAMQTVIDTFGHIDILLNNAGIAVRGGVDSMSVEDWDKSYDTNVKGIFLAS 125 Query: 410 QYLFPLLKDS--GRVINVTNAYGHLSNIKNDKWIK 508 +Y+ P +K+ G++IN+ + +++ K D +I+ Sbjct: 126 KYVVPQMKERGYGKIINIASVNAVVAD-KFDAFIR 159 >UniRef50_Q0K556 Cluster: Short chain dehydrogenase; n=1; Ralstonia eutropha H16|Rep: Short chain dehydrogenase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 263 Score = 40.3 bits (90), Expect = 0.047 Identities = 27/85 (31%), Positives = 39/85 (45%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 +VA++ G LGLAI L++ V A + + A G + L+ IT Sbjct: 19 RVALVTGGAQGLGLAIAAGLADA-GAHVLVVARNAQRVQAAVAALAARGGSAEALVLDIT 77 Query: 242 DKPALKKIADTIQMNHGSFDILINN 316 D+ A+ D I HG DIL+NN Sbjct: 78 DEAAVAAAFDRIDAAHGRLDILVNN 102 >UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Kineococcus radiotolerans SRS30216|Rep: Short-chain dehydrogenase/reductase SDR precursor - Kineococcus radiotolerans SRS30216 Length = 247 Score = 40.3 bits (90), Expect = 0.047 Identities = 31/145 (21%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 + A++ T+ +G A+ L+ + V + D+ G A ++ N G ++L A ++ Sbjct: 8 RTALVTGSTSGIGRAVAAVLAAR-GAHVLVSGRDDTRGRDAVQSLVNAGGTAEYLPADLS 66 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYE-EAKNVIDSKYKSLLIVEQYL 418 ++++AD G+ DIL+NN E + + K+ ++ Q L Sbjct: 67 AASGVRELADAALDLAGTVDILVNNAGVFSFGSTAGNSEIDIDRMYAINVKAPYLLVQAL 126 Query: 419 FPLL--KDSGRVINVTNAYGHLSNI 487 P + + SG ++NV H ++ Sbjct: 127 APKMVEQGSGTIVNVLTGAAHRGSV 151 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 40.3 bits (90), Expect = 0.047 Identities = 32/143 (22%), Positives = 63/143 (44%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KV ++ G+ +G AI +++ V S EE ++ + A Sbjct: 5 LENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAIQA 64 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPT-YEEAKNVIDSKYKSLLIVE 409 + ++ +KK+ + I+ +G DIL+NN +K T EE ++ + K + Sbjct: 65 DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124 Query: 410 QYLFPLL--KDSGRVINVTNAYG 472 + L+ SGR+IN+++ G Sbjct: 125 RAAAKLMLKHKSGRIINISSVVG 147 >UniRef50_UPI000038DA8A Cluster: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - Nostoc punctiforme PCC 73102 Length = 131 Score = 39.9 bits (89), Expect = 0.063 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 3/102 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATE-NFNNIGLYPKFL 226 ++ K+ ++ LGL VKAL+ G + E LK+ N++G L Sbjct: 7 SLKNKIVLVTGKNRGLGLETVKALANA--GAFVLVNAQSLETLKSVVVAVNSLGGKAAPL 64 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDF 346 ITDK A++K I+ +G DIL+NN D +Q +F Sbjct: 65 QLDITDKAAVEKAFIEIKDKYGRLDILVNNVGMRDRRQLFEF 106 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 39.9 bits (89), Expect = 0.063 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 6/146 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKAT--ENFNNIGLYPKFL 226 + KVAI+ + +G AI + + G A EEG ++ E +N G+ + Sbjct: 3 LKDKVAIVTGAASGMGKAIATLYASE--GAKVIVADLNEEGAQSVVEEITSNNGVATA-I 59 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAK--NVIDSKYKSLL 400 I K + K+ DT +G+ DIL+NN + E E+ + + D K ++ Sbjct: 60 KVNIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVM 119 Query: 401 IVEQYLFPLL--KDSGRVINVTNAYG 472 + P+ K+SG ++N + G Sbjct: 120 RAMRKAIPIFLEKESGVIVNTASTGG 145 >UniRef50_Q4L7K1 Cluster: Similar to 3(or 17)beta-hydroxysteroid dehydrogenase; n=1; Staphylococcus haemolyticus JCSC1435|Rep: Similar to 3(or 17)beta-hydroxysteroid dehydrogenase - Staphylococcus haemolyticus (strain JCSC1435) Length = 285 Score = 39.9 bits (89), Expect = 0.063 Identities = 36/145 (24%), Positives = 65/145 (44%), Gaps = 5/145 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEE--GLKATENFNNIGLYPKFL 226 M++ +A++ ++ LG L+EK VY T + E LK N+ L L Sbjct: 1 MNKTIALVTGASSGLGFETSLMLAEK-GFQVYATMRNLENQMNLKIEATKRNVDL--TIL 57 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 +T ++K + I G DILINN + + T EE ++ ++ Sbjct: 58 ELDVTKLDSIKSAVEFIIQEEGRIDILINNAGAGFNKTTEQATDEEINWQLNLNLMGVIR 117 Query: 404 VEQYLFPLLKD--SGRVINVTNAYG 472 + + + P+++ GRVIN+++ G Sbjct: 118 MTKAVLPIMRSQREGRVINISSVGG 142 >UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Nostocaceae|Rep: Short-chain dehydrogenase/reductase SDR - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 294 Score = 39.9 bits (89), Expect = 0.063 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKAL-SEKLNGTVYFTASDE-EEGLKATENFNNIGLYPKFL 226 ++ K AI+ G+ +GLA+ KAL SE +N + + + E + A ++ G + Sbjct: 35 LTGKTAIVTGGSAGIGLAVAKALYSEGVNVAIASRSQERLENAVSAIQSLPTPGAKVIAI 94 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN 316 A +T ++ ++ + G DILINN Sbjct: 95 SADLTQAESVDRVVSSTLAQFGQIDILINN 124 >UniRef50_Q2J935 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. (strain CcI3) Length = 245 Score = 39.9 bits (89), Expect = 0.063 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 2/137 (1%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A++ GT +G A+V L+ V EE + G + A + D Sbjct: 10 ALVTGGTRGIGRAVVLGLARAGATVVAGHQRQTEEAESLRRELKDTGGDHLLVQADVADP 69 Query: 248 PALKKIADTIQMNHGSFDILINNTEDLKQCE--DFPTYEEAKNVIDSKYKSLLIVEQYLF 421 + ++ + + G DI++NN + P +E V+ + + +V Q Sbjct: 70 GQITELVEATGTHLGGLDIVVNNVGTISHIPYAQLPL-DEWTQVLTTNLTATHLVTQGAL 128 Query: 422 PLLKDSGRVINVTNAYG 472 LL DSG VIN+ + G Sbjct: 129 SLLGDSGSVINIGSGSG 145 >UniRef50_Q9WWC0 Cluster: AtsC; n=3; Agrobacterium tumefaciens|Rep: AtsC - Agrobacterium tumefaciens Length = 254 Score = 39.9 bits (89), Expect = 0.063 Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 8/159 (5%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 T + A++ +GLAI + L TV+ D G A G+ + + Sbjct: 8 THTPPTALVTGANKGIGLAIARQLGAA-GHTVWLGCRDMSRGEMAAFELRENGVDARAVQ 66 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF---PTYEEAKNVIDSKYKSLL 400 +TD + A TI+ G D+L+NN + + +E + + ++ ++ Sbjct: 67 LDVTDDASASSAAKTIESEVGHLDVLVNNAGLMFGSPPSLAEESIDEIQQMFNTNVFGVM 126 Query: 401 IVEQYLFPLLKDS--GRVINVTNAYGHLS---NIKNDKW 502 V Q PLL+ S R++ +++ L+ +++++ W Sbjct: 127 RVTQAFLPLLRKSKAARIVMMSSGLSSLTDALDMRSETW 165 >UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogenase; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Short-chain alcohol-related dehydrogenase - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 272 Score = 39.9 bits (89), Expect = 0.063 Identities = 41/143 (28%), Positives = 65/143 (45%), Gaps = 4/143 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 +V ++ G++ +G +I L EK G + + S F I L +L T Sbjct: 3 QVVLVTGGSSGIGKSICLYLHEK--GYIVYGTSRNPARYAHEVPFKLIALD---VLDDTT 57 Query: 242 DKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 PALK I D G D+L+NN L ED T EE K V ++ +L Q Sbjct: 58 ITPALKTIIDA----EGKLDVLVNNAGIGMLGSIED-STAEEVKEVFETNVYGILRTCQA 112 Query: 416 LFPLLKD--SGRVINVTNAYGHL 478 + P +++ G +INV++ G++ Sbjct: 113 VLPHMRERKMGLIINVSSIAGYM 135 >UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 249 Score = 39.9 bits (89), Expect = 0.063 Identities = 32/149 (21%), Positives = 68/149 (45%), Gaps = 5/149 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKA-TENFNNIGLYPKFLL 229 +S +VA++ ++ G A+ L++ G A+ E+ L+A + + G + ++ Sbjct: 5 LSGRVALVTGASSGFGEAVALDLAKA--GAKVALAARREDRLRALAQRITDAGGQAQVIV 62 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYE--EAKNVIDSKYKSLLI 403 A TD+ ++ + G DILINN + E T + +++++ L+ Sbjct: 63 ADFTDEHQAQRAVRETEAAFGWLDILINNA-GVMYLEPVATADLGRWRSMLELNLLGLIA 121 Query: 404 VEQYLFP--LLKDSGRVINVTNAYGHLSN 484 Q P + G ++N+ + GH++N Sbjct: 122 ATQAALPGMTARKDGHIVNIASTAGHIAN 150 >UniRef50_Q0K0G0 Cluster: Short chain dehydrogenase; n=2; Bacteria|Rep: Short chain dehydrogenase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 253 Score = 39.9 bits (89), Expect = 0.063 Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 1/135 (0%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ KVA+I GT +GLAI K + V TA +E +A K Sbjct: 4 SLEGKVAVITGGTTGIGLAIAKEFVAE-GAKVVVTALQQEALDEAVREIGPRSFGAKADA 62 Query: 230 AQITDKPALKKIADTIQMNHGSFD-ILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 + I + AL K ++ +HG D ++ N D T E+ ++ K +L Sbjct: 63 SSIAEMDALLK---RVKADHGRLDAVIANAVADEHAPLGKITEEQFDKMVGVNLKGVLFT 119 Query: 407 EQYLFPLLKDSGRVI 451 Q PLL+ G +I Sbjct: 120 IQSAMPLLESDGSII 134 >UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3; Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase - Eubacterium sp. (strain VPI 12708) Length = 266 Score = 39.9 bits (89), Expect = 0.063 Identities = 33/151 (21%), Positives = 63/151 (41%), Gaps = 6/151 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KV ++ T +GLAI +A +++ VY A + E + N G K++ Sbjct: 3 LKDKVILVTASTRGIGLAIAQACAKE-GAKVYMGARNLERAKARADEMNAAGGNVKYVYN 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNV----IDSKYKSLL 400 T + + + I G D+L+NN +D V ++ KS+ Sbjct: 62 DATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSVF 121 Query: 401 IVEQYLFPLLKDS--GRVINVTNAYGHLSNI 487 I Q + ++ G +IN+++ G + +I Sbjct: 122 IASQTAVKYMAENGGGSIINISSVGGLIPDI 152 >UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Reinekea sp. MED297|Rep: Short-chain alcohol dehydrogenase-like protein - Reinekea sp. MED297 Length = 672 Score = 39.9 bits (89), Expect = 0.063 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 5/149 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KV +I G++ +G A LS K TV A D E+ +A + + G A Sbjct: 382 LNGKVVLITGGSSGIGKATAMRLS-KAGATVIICARDAEKLRRAHLDIESTGGTVVSHQA 440 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT-EDLKQ--CEDFPTYEEAKNVIDSKYKSLLI 403 IT + ++ I+ DILINN +++ + + + I+ Y + + Sbjct: 441 DITQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVA 500 Query: 404 VEQYLFPLL--KDSGRVINVTNAYGHLSN 484 + P++ + G VIN+ ++ G LSN Sbjct: 501 ITLKALPMMDRRREGHVINI-SSIGVLSN 528 >UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reinekea sp. MED297|Rep: Short chain dehydrogenase - Reinekea sp. MED297 Length = 271 Score = 39.9 bits (89), Expect = 0.063 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 7/141 (4%) Frame = +2 Query: 71 IIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLK-ATENFNNIGLYPKFLLAQITDK 247 +I G + LGLA+ + ++ GT E+G + A + +G F+ +TD Sbjct: 5 VITGGASGLGLAMAQRWAK--TGTNICLIDRNEDGAEFALQKLQRLGATAFFICCDVTDD 62 Query: 248 PALKKIADTIQMNHGSFDILINN----TEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 A+ +A ++ G+ DILIN+ T + E ++ N+ + V + Sbjct: 63 NAVAAMAAKVKQQLGTIDILINSAGVPTAGSIEAESIDVWQWVLNI---NLMGTVRVTKA 119 Query: 416 LFPLLKDSGR--VINVTNAYG 472 L PL++ G+ +INV + G Sbjct: 120 LGPLMRQQGKGHIINVASQAG 140 >UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR; n=18; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 257 Score = 39.9 bits (89), Expect = 0.063 Identities = 25/85 (29%), Positives = 39/85 (45%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA+I G + +GLA K + + T+ D G ++ N F+ ++ Sbjct: 10 KVAVITGGASGIGLATAKRMRAE-GATIVIGDIDPATGKTVADDLNGT-----FVQVDVS 63 Query: 242 DKPALKKIADTIQMNHGSFDILINN 316 D+ A+ + DT HGS DI NN Sbjct: 64 DQVAVDALFDTAAEEHGSVDIAFNN 88 >UniRef50_Q75JB9 Cluster: Similar to Lactococcus lactis (Subsp. lactis) (Streptococcus lactis). Oxidoreductase; n=3; Dictyostelium discoideum|Rep: Similar to Lactococcus lactis (Subsp. lactis) (Streptococcus lactis). Oxidoreductase - Dictyostelium discoideum (Slime mold) Length = 287 Score = 39.9 bits (89), Expect = 0.063 Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 11/146 (7%) Frame = +2 Query: 74 IINGTNI-LGLAIVKALSEKLNGTVYFTASD---EEEGLKATENFNNIGL-YPKFLLA-- 232 +++GT+ LGL+IVK L + FT S E E K EN N + Y LLA Sbjct: 12 LVSGTSTGLGLSIVKRLLDNNYKVAAFTRSKLIVENEIKKYYENNNEKNIDYLNSLLAVQ 71 Query: 233 -QITDKPALKK-IADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 IT++ +++ + +T+ G FD++INN A+ + D Y ++L + Sbjct: 72 VDITNEESVENGVKETVN-KFGHFDVVINNAG------------YARAIFDVNYFAILNI 118 Query: 407 EQYLFPLLKD--SGRVINVTNAYGHL 478 + P L+ SG ++NV++ GHL Sbjct: 119 VRSTTPYLRKQKSGLILNVSSIVGHL 144 >UniRef50_Q176N3 Cluster: Short-chain dehydrogenase; n=3; Culicidae|Rep: Short-chain dehydrogenase - Aedes aegypti (Yellowfever mosquito) Length = 342 Score = 39.9 bits (89), Expect = 0.063 Identities = 23/85 (27%), Positives = 43/85 (50%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 ++A++ G N LG I L+++ + D G K ++ +G+ KF A I+ Sbjct: 76 QLALVTGGANGLGREICLQLAKE-GCHIAVNDLDATNGAKTVDDLKKMGVKAKFFKADIS 134 Query: 242 DKPALKKIADTIQMNHGSFDILINN 316 + A++ + I+ + G DIL+NN Sbjct: 135 NYDAVQGLRKEIESSLGPVDILVNN 159 >UniRef50_P50200 Cluster: NADP-dependent 7-alpha-hydroxysteroid dehydrogenase; n=1; Clostridium sordellii|Rep: NADP-dependent 7-alpha-hydroxysteroid dehydrogenase - Clostridium sordellii Length = 267 Score = 39.9 bits (89), Expect = 0.063 Identities = 37/153 (24%), Positives = 68/153 (44%), Gaps = 8/153 (5%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KVA++ + T +GLA L++ VY E + + + GL K + Sbjct: 4 LENKVALVTSATRGIGLASAIKLAQN-GAIVYMGVRRLEATQEICDKYKEEGLILKPVFF 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN------TEDLKQCE-DFPTYEEAKNV-IDSKY 388 + K++ DTI N G DIL+NN +DL D T+ E N + S Y Sbjct: 63 DAYNIDIYKEMIDTIIKNEGKIDILVNNFGTGRPEKDLDLVNGDEDTFFELFNYNVGSVY 122 Query: 389 KSLLIVEQYLFPLLKDSGRVINVTNAYGHLSNI 487 + ++ ++ + G ++N+++ G + +I Sbjct: 123 RLSKLIIPHM--IENKGGSIVNISSVGGSIPDI 153 >UniRef50_Q98H76 Cluster: Short chain dehydrogenase; n=3; Mesorhizobium loti|Rep: Short chain dehydrogenase - Rhizobium loti (Mesorhizobium loti) Length = 251 Score = 39.5 bits (88), Expect = 0.083 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 1/89 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 M+ K ++I G N +GL + L+ + V+ A D E G A + N GL ++L Sbjct: 3 MTTKANVLITGANKGIGLETARRLAA-MGFNVWLGARDAERGEAAAKALRNEGLDVEWLA 61 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 + ++ A T+ S D+L+NN Sbjct: 62 LDVASDDSVAAAARTLTARVSSLDVLVNN 90 >UniRef50_Q8UJN8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=2; Rhizobiales|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 248 Score = 39.5 bits (88), Expect = 0.083 Identities = 35/137 (25%), Positives = 58/137 (42%), Gaps = 2/137 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 MS KVA+++ G +GLAI + LSE+ V+ T+ E+ KA IG + A Sbjct: 9 MSSKVALVVGGAKGIGLAIAERLSEE-GAKVFITSRRSEDAEKAA---TAIGHGAIGIAA 64 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 + + ++ HG D L+ N + Q + T E D + ++ Sbjct: 65 DAAIPEDMVATVEKVRKAHGRIDALVLNAGLSEPAQIAEI-TPEHFDRHFDVNVRGMVFG 123 Query: 407 EQYLFPLLKDSGRVINV 457 Q P + + G V+ V Sbjct: 124 FQAALPAMTEGGSVVLV 140 >UniRef50_Q5KZI9 Cluster: Dehydrogenase; n=5; Bacilli|Rep: Dehydrogenase - Geobacillus kaustophilus Length = 257 Score = 39.5 bits (88), Expect = 0.083 Identities = 30/144 (20%), Positives = 61/144 (42%), Gaps = 4/144 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K A++ +G AI +E V A E + + + G + Sbjct: 11 KTALVTGAGRGIGRAIAIGFAEA-GADVALIARTEADLQETASHIEQFGRKAYIYPLDVI 69 Query: 242 DKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYL 418 D+ A+ ++ GS DI++NN +++ T E + ++++ KS +V Q Sbjct: 70 DRKAVHDAVANVKQQAGSLDIVVNNAGMNIRTPALDVTDHEWETIMNTNLKSAFLVSQEA 129 Query: 419 FPLLKDS---GRVINVTNAYGHLS 481 ++K+ G +IN+ + GH++ Sbjct: 130 GRVMKEQKQGGNIINIASVAGHVA 153 >UniRef50_Q47QD3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Thermobifida fusca YX|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Thermobifida fusca (strain YX) Length = 249 Score = 39.5 bits (88), Expect = 0.083 Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 6/146 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVA++ + +G AI + +E+ G + A+ + L+ E N + Sbjct: 5 LNGKVALVTGASRGIGAAIARGYAER--GALVVGAARSTDQLRELEATNPERI--STATV 60 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPT--YEEAKNVIDSKYKSLLIV 406 + D +L + D + HG DIL+NN + DF T E+ + + + + + Sbjct: 61 DLRDAESLNSLVDLVVERHGRIDILVNNA-GVAPAADFATEPIEQWRTTFEVNVIAPMTL 119 Query: 407 EQ----YLFPLLKDSGRVINVTNAYG 472 Q Y P + SG++IN+ + G Sbjct: 120 AQAAGRYFIP--QRSGKIINIASTTG 143 >UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=4; Bacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Myxococcus xanthus (strain DK 1622) Length = 348 Score = 39.5 bits (88), Expect = 0.083 Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 3/140 (2%) Frame = +2 Query: 71 IIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDKP 250 +I G+ LGL + + L ++ V DE+ +A E G + + D Sbjct: 45 LITGGSRGLGLVLARQLLKE-EARVAICGRDEQTLERAREELERTGGEVYAIPCDVRDPV 103 Query: 251 ALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIVEQYLFPL 427 ++ + I G+ D+LINN ++ + T E+ + ID+ + L + P Sbjct: 104 QVEAMVSAIHERWGTVDVLINNAGVIQVGPLESMTLEDFQEAIDTHLWAPLYTTLAVLPE 163 Query: 428 LK--DSGRVINVTNAYGHLS 481 +K GR++N+ + G +S Sbjct: 164 MKRRGKGRIVNIASVGGKVS 183 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 39.5 bits (88), Expect = 0.083 Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 4/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S KVA++ LG AI L+ + DE G + EN + Sbjct: 4 LSGKVALVTGAARGLGEAIAVELAAQGARVALLDVLDEL-GAEVAENIKKSSGNAYYRNC 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIV 406 I D ++ D + +G D+L+NN P E N+ + S+ Sbjct: 63 DIRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRF 122 Query: 407 EQYLFPLLKDS--GRVINVTNAY 469 +++ P ++++ G VIN+++ + Sbjct: 123 CRFVLPRMQEAGGGAVINMSSVH 145 >UniRef50_A6DTR6 Cluster: FabG; n=1; Lentisphaera araneosa HTCC2155|Rep: FabG - Lentisphaera araneosa HTCC2155 Length = 251 Score = 39.5 bits (88), Expect = 0.083 Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 5/143 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ KVA++ + LG AI K +E V E + + +G + Sbjct: 4 SLENKVALVTGSSKGLGKAINKRFAEAGAKVVVNYCHSECTAQETYDELVAMGAEALMIR 63 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNT---EDLKQCEDFPTYEEAKNVIDSKYKSLL 400 A +TD+ + ++ I+ G DILI N + K E++ ++++ ++I+ KS Sbjct: 64 ADVTDEAQVNEMVAEIEEKLGPIDILIPNATPDQPQKPIEEY-SWDDYMSMINFFIKSPY 122 Query: 401 IVEQYLFPLLK--DSGRVINVTN 463 ++ + + P +K GRVI++ + Sbjct: 123 LLTKAVLPSMKKRKKGRVISIAS 145 >UniRef50_A1UP20 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=7; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 244 Score = 39.5 bits (88), Expect = 0.083 Identities = 34/146 (23%), Positives = 69/146 (47%), Gaps = 6/146 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + +++A++ GT+ +GLA + L+ + V + D E G +A IG +F+ A Sbjct: 3 LDKQIALVTGGTSGIGLASARLLAAE-GAEVVVSGRDAERGAQAVA---EIGGAVRFVQA 58 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQC----EDFPTYEEAKNVIDSKYKS-- 394 ++D ++K +A+ G DIL+NN +D ++E + D+ + Sbjct: 59 DMSDPQSVKDLAE----QAGDVDILVNNAGVFPAAPTLDQDLASFE---TMFDTNVRGAY 111 Query: 395 LLIVEQYLFPLLKDSGRVINVTNAYG 472 L+ E + + G ++N+T+ G Sbjct: 112 FLVAEVARGMVARGRGAIVNITSPAG 137 >UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=9; Bacteria|Rep: 2 deoxy-D-gluconate 3-dehydrogenase - Clostridium acetobutylicum Length = 260 Score = 39.1 bits (87), Expect = 0.11 Identities = 38/176 (21%), Positives = 77/176 (43%), Gaps = 4/176 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ KVAI+ G LG AL++ G F + + + + G +F Sbjct: 14 SLKGKVAIVTGGNTGLGQGYALALAKA--GADLFIVTHGTNWDETRKLIEDEGRKVEFYK 71 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY--EEAKNVIDSKYKSLLI 403 A ++ K ++ I D +G DIL+NN +++ Y E+ + +I++ S+ Sbjct: 72 ADLSKKESIPGIFDKCMELYGRLDILVNNAGTIRRA-PITEYRDEDWEYIINTNLNSIYH 130 Query: 404 VEQYLFPLL--KDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEE 565 + Q ++ + SG++IN+ + + + + K++ TA V + F E Sbjct: 131 LSQRAAKIMIKQGSGKIINIAS----MLSFQGGKFVPPYTASKHGVAGLTKAFANE 182 >UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Geobacillus kaustophilus Length = 256 Score = 39.1 bits (87), Expect = 0.11 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 11/148 (7%) Frame = +2 Query: 65 VAIIINGTNILGLAIVKALSEKLNGTVYF---TASDEEEGLKATENFNNIGLYPKFLLAQ 235 VA+I G + +G A L+++ TV TA EE ++ G+ +F A Sbjct: 7 VAVITGGGSGIGRATAVRLAQE-GATVVLVGRTAVKLEETVQDITRLGVPGVADRFA-AD 64 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFP-TYEEAKNVIDSKYKSLLIVEQ 412 +TD ++ +A +Q +G +L+NN + T +E +V KS+ +V Q Sbjct: 65 VTDHEQVRALAAYVQNRYGDLHVLVNNAGISTHTKWLELTEQEWDDVQRVNMKSVFLVSQ 124 Query: 413 YLFPLLKDSGR-------VINVTNAYGH 475 L PL+ + + ++NV + GH Sbjct: 125 TLAPLMIEGAKRERANRAIVNVASLSGH 152 >UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Bacillus thuringiensis serovar israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 248 Score = 39.1 bits (87), Expect = 0.11 Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 8/145 (5%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIG-----LYPKFL 226 +VA++I G+ +G AI L+ + VYFT ++ A E N IG +P + Sbjct: 6 EVALVIGGSRGIGKAITMDLANQ-GLIVYFTFQSNQKS--ANEIANTIGEKGGQAFPMHV 62 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQ-CEDFPTYEEAKNVIDSKYK-SLL 400 IT++ ++ K+ I+ DIL+NN + + E+ +V+D K + L Sbjct: 63 --DITNEDSIHKLFQHIRSKEKRIDILVNNAGVINDGFAAMMSEEKWDHVVDLNLKGTFL 120 Query: 401 IVEQYLFPLLKDS-GRVINVTNAYG 472 Q L +++ G ++N+T+ G Sbjct: 121 CCRQALRIMMRQKRGSIVNITSTSG 145 >UniRef50_Q0FSI1 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=2; Alphaproteobacteria|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - Roseovarius sp. HTCC2601 Length = 258 Score = 39.1 bits (87), Expect = 0.11 Identities = 41/156 (26%), Positives = 72/156 (46%), Gaps = 13/156 (8%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEE----GLKATENFNNIGLYPK 220 ++ +VAII G++ +G AIV+ + + G F A EE G E G Sbjct: 5 LAGRVAIITGGSSGIGRAIVRKYAAE--GAHVFVADITEEAVEGGRPVCEVVAEEGGSAV 62 Query: 221 FLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKS 394 F+ ++ A++ + D G DIL+NN L+ + EEA V+D K Sbjct: 63 FVKTDVSCADAVEALVDRASAQTGRLDILVNNAV-LRAGKPLVETEEADWDRVMDVSLKG 121 Query: 395 LLI-----VEQYLFPLLKDS--GRVINVTNAYGHLS 481 + V Q + +++ GR+I++++ +GH+S Sbjct: 122 AYLCARAAVRQMMTQEIREEVRGRLIHISSQHGHVS 157 >UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Enterobacter sp. 638|Rep: Short-chain dehydrogenase/reductase SDR precursor - Enterobacter sp. 638 Length = 242 Score = 39.1 bits (87), Expect = 0.11 Identities = 30/143 (20%), Positives = 68/143 (47%), Gaps = 2/143 (1%) Frame = +2 Query: 59 QKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 ++VA++ ++ +G A+ + L+ V E + A+E +G + A + Sbjct: 7 KRVAVVTGASSGIGEALARELAGNGIQVVLLARRFERIDVLASE----LGHGAIAIKADV 62 Query: 239 TDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 TD+ ++ A+ ++ G DILINN L D +E + ++++ + V + Sbjct: 63 TDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLGAMTVTEV 122 Query: 416 LFP-LLKDSGRVINVTNAYGHLS 481 P L ++ G ++N+++ G ++ Sbjct: 123 FLPQLRRNKGDLVNISSVAGRVA 145 >UniRef50_A1SET6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR precursor - Nocardioides sp. (strain BAA-499 / JS614) Length = 249 Score = 39.1 bits (87), Expect = 0.11 Identities = 37/161 (22%), Positives = 73/161 (45%), Gaps = 8/161 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLK-ATENFNNIGLYPKFLLAQI 238 + A++ G++ +GLAI + L G AS + L+ A G + Sbjct: 5 RAALVTGGSSGIGLAIARTLGAA--GYDVTLASRRPDRLEQAAHGLREEGYRVATSAGDL 62 Query: 239 TDKPALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQY 415 D+ A+ +T + +G D+L+NN + Q D T + +++ +S+ + + Sbjct: 63 GDEAAVVAAVETHRAAYGRLDVLVNNAGVGIGQFADDLTTKAIDIQLNTNLRSIFLFYRE 122 Query: 416 LFPLLKDSG------RVINVTNAYGHLSNIKNDKWIKTLTA 520 P+L+++G VINV++A S I ++W+ +A Sbjct: 123 ALPMLREAGGEHRNALVINVSSA----SGIHGERWLGVYSA 159 >UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=4; Bacillaceae|Rep: Uncharacterized oxidoreductase yoxD - Bacillus subtilis Length = 238 Score = 39.1 bits (87), Expect = 0.11 Identities = 36/147 (24%), Positives = 69/147 (46%), Gaps = 6/147 (4%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALS-EKLN-GTVYFTASDEEEGLKATENFNNIGLYPKF 223 ++ K A+I G +G A AL+ E +N G + T+++ E K E +G+ F Sbjct: 3 SLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVE---KVAEEVKALGVKAAF 59 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF--PTYEEAKNVIDSKYKSL 397 A + D + + ++ G DILINN + + F + +E +N+I + Sbjct: 60 AAADVKDADQVNQAVAQVKEQLGDIDILINNA-GISKFGGFLDLSADEWENIIQVNLMGV 118 Query: 398 LIVEQYLFP--LLKDSGRVINVTNAYG 472 V + + P + + +G +IN+++ G Sbjct: 119 YHVTRAVLPEMIERKAGDIINISSTAG 145 >UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bacteria|Rep: Putative ketoacyl reductase - Streptomyces coelicolor Length = 261 Score = 39.1 bits (87), Expect = 0.11 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKAT-ENFNNIGLYPKFL 226 T +VA++ T+ +GL I + L ++ G F + EEGL+ T + G+ Sbjct: 3 TQDSEVALVTGATSGIGLEIARRLGKE--GLRVFVCARGEEGLRTTLKELREAGVEADGR 60 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINN 316 + P ++ + + +G D+L+NN Sbjct: 61 TCDVRSVPEIEALVAAVVERYGPVDVLVNN 90 >UniRef50_Q2CJB6 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Oceanicola granulosus HTCC2516|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Oceanicola granulosus HTCC2516 Length = 252 Score = 38.7 bits (86), Expect = 0.14 Identities = 29/149 (19%), Positives = 65/149 (43%), Gaps = 7/149 (4%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKAT-ENFNNIGLYPKFL 226 ++ KVA++ + +G A L+ + V TA + ++A +G K + Sbjct: 9 SLDGKVAVVTGASRRIGRATALGLA-RCGADVVVTARSARDEIEAVAREIEGLGQRAKVV 67 Query: 227 LAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE----DFPTYEEAKNVIDSKYKS 394 + ++D+ +++ ++ G D+L+NN +Q F + E + VI Sbjct: 68 MGDVSDEAEARRMGAEVRDAFGRVDVLVNNAAIRRQVSLLEMSFADWREIQGVI---LDG 124 Query: 395 LLIVEQYLFPLLKDS--GRVINVTNAYGH 475 ++ + L P + ++ G ++N+ GH Sbjct: 125 AFLMARELLPAMIETGGGTIVNIGGLTGH 153 >UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8; Bacteria|Rep: Short-chain alcohol dehydrogenase - Burkholderia dolosa AUO158 Length = 284 Score = 38.7 bits (86), Expect = 0.14 Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 M+ KV +I ++ +G A K L+ K TV A ++ + G Sbjct: 42 MANKVVVITGASSGIGEATAKLLASK-GATVALAARRLDKLQRVAAEIVAKGGQVSVHQV 100 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLLIVE 409 +TD+ + ++ + + HG D+++NN + +E +ID K LL Sbjct: 101 DVTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGV 160 Query: 410 QYLFPLL--KDSGRVINVTNAYG 472 P+ + SG +N+ + G Sbjct: 161 AAALPVFEKQQSGHFVNIASVVG 183 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 38.7 bits (86), Expect = 0.14 Identities = 25/88 (28%), Positives = 42/88 (47%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S KVA+I + +G AI K L+E+ V ++ ++E + + F GL + Sbjct: 9 LSGKVAVITGSSKGIGKAIAKGLAEQ-GAQVVISSRNQEACDEVAKEFKEQGLDTIGIAC 67 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN 316 I + K + D + G DIL+NN Sbjct: 68 HIGKEDQRKNLVDKTIESFGRIDILVNN 95 >UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR; n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 251 Score = 38.7 bits (86), Expect = 0.14 Identities = 30/132 (22%), Positives = 54/132 (40%), Gaps = 2/132 (1%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDK 247 A++ G+ +G IV+ L+ + + S + K + + G + A +D Sbjct: 14 ALVTGGSRGIGAEIVRRLAFEGAAVAFTYGSSVSDADKVVVDVSRGGGRVLPIRADSSDA 73 Query: 248 PALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 + D G DIL+NN L E FP ++ ++ + + + Q Sbjct: 74 GQIASAVDETVTRLGGLDILVNNAGVAHLGAVESFPL-DQFDRLVAVNVRGVFVAIQCAV 132 Query: 422 PLLKDSGRVINV 457 P L D GR+IN+ Sbjct: 133 PHLGDGGRIINI 144 >UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 248 Score = 38.7 bits (86), Expect = 0.14 Identities = 33/144 (22%), Positives = 63/144 (43%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 +S KVAI+ +G I L+ +G + + + E +G L Sbjct: 4 LSGKVAIVTGAGQGIGRGIALRLAR--DGAIVVATDITGKENEVAEEVRKLGGQGMALRL 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF--PTYEEAKNVIDSKYKSLLIV 406 +TD +++A T+ +G DIL+NN + + F T+ + VI+ + V Sbjct: 62 DVTDGKMAEEVARTVFDKYGHIDILVNNA-GIYPFKPFMEMTFNDWYRVINVNLNGVFNV 120 Query: 407 EQYLFPLL--KDSGRVINVTNAYG 472 + + P + + +GR+IN+ + G Sbjct: 121 TRAVVPYMVKQKNGRIINIASIAG 144 >UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=26; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 248 Score = 38.7 bits (86), Expect = 0.14 Identities = 24/89 (26%), Positives = 35/89 (39%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 T+ K I+ G+ +GL IVK E V +EE G E+ +G F Sbjct: 4 TLVGKKVIVTGGSRGIGLGIVKLFLEN-GADVEIWGLNEERGQAVIESLTGLGGEVSFAR 62 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 ++ +K H DIL+NN Sbjct: 63 VDVSHNGGVKDCVQKFLDKHNKIDILVNN 91 >UniRef50_Q8G6W8 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; Bifidobacterium|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Bifidobacterium longum Length = 267 Score = 38.3 bits (85), Expect = 0.19 Identities = 32/143 (22%), Positives = 63/143 (44%), Gaps = 9/143 (6%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 + AII +G A+ K L+ V D + E+ +++G + A + Sbjct: 18 RTAIITGSGKGIGAAVAKCLASHGAAVVINYVHDAASAQRTVEDIHSLGGSAIAVQADVC 77 Query: 242 DKPALKKIADTIQMNHGSFDILINN-----TEDLKQCEDFP--TYEEAKNVIDSKYKSLL 400 D+ K+ T + G DIL+NN + D ++ F ++E I+ Sbjct: 78 DESQSSKLVGTAVDSFGGVDILVNNAFGRFSFDPRRRSTFAGGDWDEFSAQIEGCLHGAY 137 Query: 401 IVEQYLFPLLK--DSGRVINVTN 463 ++ ++ PL++ SGR+IN+++ Sbjct: 138 LMCSHVVPLMRAQTSGRIINISS 160 >UniRef50_Q62JY9 Cluster: Acetoacetyl-CoA reductase; n=58; cellular organisms|Rep: Acetoacetyl-CoA reductase - Burkholderia mallei (Pseudomonas mallei) Length = 246 Score = 38.3 bits (85), Expect = 0.19 Identities = 33/143 (23%), Positives = 65/143 (45%), Gaps = 3/143 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 MSQ++A + G +G +I + L + V + +K E+ +G Sbjct: 1 MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEG 60 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCE-DFPTYEEAKNVIDSKYKSLL-IV 406 + D + K+ D ++ G D+L+NN + T E+ + VID+ SL + Sbjct: 61 NVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVT 120 Query: 407 EQYLFPLLKDS-GRVINVTNAYG 472 +Q + +++ GR+IN+++ G Sbjct: 121 KQVIDGMVERGWGRIINISSVNG 143 >UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 247 Score = 38.3 bits (85), Expect = 0.19 Identities = 33/147 (22%), Positives = 70/147 (47%), Gaps = 4/147 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KV II G + +G A V A K V ++E G A + + G F+ Sbjct: 4 LTNKVVIITGGASGIGRAAVDAFLAK-GAKVVIADFNKETGEAAVKELTDAGKQVLFVQT 62 Query: 233 QITDKPALKK-IADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLLIV 406 ++++P+++ +A+T++ + DILINN TYE+ + ++ + + Sbjct: 63 DVSNEPSVQNMVAETVKA-YERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFLG 121 Query: 407 EQY-LFPLLKDSGR-VINVTNAYGHLS 481 ++ + ++K G +IN ++ G ++ Sbjct: 122 SKHAIKEMIKTGGGCIINTSSILGSVA 148 >UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 38.3 bits (85), Expect = 0.19 Identities = 23/87 (26%), Positives = 42/87 (48%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVAI+ G ++G A+ + L+ + V D E G + ++ +G F+ Sbjct: 4 LAGKVAIVTGGATLIGAAVAQDLN-RAGACVAILDLDVENGTRVADS---LGERAMFVAL 59 Query: 233 QITDKPALKKIADTIQMNHGSFDILIN 313 ITD A++ I G+ D+L+N Sbjct: 60 DITDDRAIEHAVAAIVERFGAIDVLVN 86 >UniRef50_Q1IP06 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 344 Score = 38.3 bits (85), Expect = 0.19 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 5/146 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENF--NNIGLYPKF 223 TM QKVA+I ++ GL +S V T + + K E N Sbjct: 60 TMEQKVALITGASSGFGLLTAVEMSAA-GYRVVATMRNPDRRSKLDEALAARNPSTPIDV 118 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINNTE-DLKQCEDFPTYEEAKNVIDSKYKSLL 400 ITD A+ ++ D + HG D+L+NN L + + +E + D+ + + Sbjct: 119 RQLDITDSAAIPRVIDEVVATHGRIDVLVNNAGFALAGFLEDISLDELRRQFDTNFFGHV 178 Query: 401 IVEQYLFPLLK--DSGRVINVTNAYG 472 V + + P+++ SG +I + + G Sbjct: 179 AVTKAVLPVMRRQRSGHIIMIGSISG 204 >UniRef50_Q10XK9 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Cyanobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Trichodesmium erythraeum (strain IMS101) Length = 226 Score = 38.3 bits (85), Expect = 0.19 Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 5/146 (3%) Frame = +2 Query: 62 KVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQI 238 K I+I G + LG AI + L TV A + T ++N +F + Sbjct: 2 KKLIVITGISRGLGRAITEEFIN-LGHTVIGCARSKSAVENLTHKYSNSH---QFSCVNV 57 Query: 239 TDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDF--PTYEEAKNVIDSKYKSLLIVEQ 412 D+ +++ A N+ + D+LINN + Q EE +ID K ++ V + Sbjct: 58 ADENNVQEWAKYTLANYSAPDLLINNAAIINQPAPLWKVDSEEFSQLIDINIKGVVNVIR 117 Query: 413 YLFPLL--KDSGRVINVTNAYGHLSN 484 Y P + + SG ++N+++ +G S+ Sbjct: 118 YFVPAMISRGSGIIVNISSGWGRSSS 143 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 38.3 bits (85), Expect = 0.19 Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 1/88 (1%) Frame = +2 Query: 56 SQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKAT-ENFNNIGLYPKFLLA 232 S KV II +G A+ AL G A +EE K T + I +FL+ Sbjct: 10 SDKVMIITGAAGGIGKAV--ALRAAKEGAKLVLADRKEEMSKETLKEIREITSNVEFLIC 67 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN 316 + + KK+ DT G DILINN Sbjct: 68 DLREGENCKKVIDTAIKKFGGLDILINN 95 >UniRef50_Q039Y3 Cluster: Short-chain alcohol dehydrogenase; n=1; Lactobacillus casei ATCC 334|Rep: Short-chain alcohol dehydrogenase - Lactobacillus casei (strain ATCC 334) Length = 311 Score = 38.3 bits (85), Expect = 0.19 Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 4/136 (2%) Frame = +2 Query: 68 AIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFN-NIGLYP-KFLLAQIT 241 A++ GT+ +G A+ AL TV +G+ A G F+ A + Sbjct: 21 AVVTGGTSGVGFAMSAALLRH-GATVIIVGKQASKGVTAAAKLRAQTGQQNVTFMGADLA 79 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLF 421 D+ A K +A+ + DILINN + + T + + + Y + I+ L Sbjct: 80 DQAATKHLANRLLRMLPKLDILINNAGVMMPAKRTLTRDGLELMWAVNYFAGFILTSELM 139 Query: 422 PLL--KDSGRVINVTN 463 PLL D RV+NV + Sbjct: 140 PLLLRSDHARVVNVAS 155 >UniRef50_A6QK68 Cluster: Oxidoreductase; n=12; Staphylococcus aureus|Rep: Oxidoreductase - Staphylococcus aureus (strain Newman) Length = 234 Score = 38.3 bits (85), Expect = 0.19 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 4/148 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 K+ +I G LG A +AL + L VY + ++ G +A++ +G++ ++ +T Sbjct: 3 KIVLITGGNKGLGYASAEAL-KALGYKVYIGSRNDVRGQQASQK---LGVH--YVQLDVT 56 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQ--CEDFPTYEEAKNVIDSKYKSLLIVEQY 415 ++K + I G DILINN Q T + + V + ++ + Sbjct: 57 SDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNT 116 Query: 416 LFPLLKDSGR--VINVTNAYGHLSNIKN 493 PLL+ S + V+NV++ G + N Sbjct: 117 FVPLLEKSEQPVVVNVSSGLGSFGMVTN 144 >UniRef50_A4AEV0 Cluster: Short chain dehydrogenase; n=1; marine actinobacterium PHSC20C1|Rep: Short chain dehydrogenase - marine actinobacterium PHSC20C1 Length = 316 Score = 38.3 bits (85), Expect = 0.19 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLK---ATENFNNIGLYPKF 223 +S KVAI+ + LGLA +AL V T + E+ E+ N + Sbjct: 15 LSGKVAIVTGANSGLGLATSRALLAAGAHVVMTTRTSEKAATAQAAVVESLGNAAAVAET 74 Query: 224 LLAQITDKPALKKIADTIQMNHGSFDILINN 316 +L + D ++++ ++ H D+LINN Sbjct: 75 MLLDLADLESIRRFSEEFHGKHSRLDLLINN 105 >UniRef50_A3YFY3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Marinomonas sp. MED121|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Marinomonas sp. MED121 Length = 271 Score = 38.3 bits (85), Expect = 0.19 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Frame = +2 Query: 35 AFGI*TMSQKVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGL 211 A I + +KV +I G LG A +A + L+G V TA + + + +G Sbjct: 12 ALNIFNLKEKVVVITGGNGTLGAAYAQAFA--LHGAKVVVTARNMSTLEETVASVRRVGG 69 Query: 212 YPKFLLAQITDKPALKKIADTIQMNHGSFDILINN 316 + + +TD ++ + + I + G DILINN Sbjct: 70 DCVAIASDVTDPIGVQSLVEKIDADFGQIDILINN 104 >UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella woodyi ATCC 51908 Length = 255 Score = 38.3 bits (85), Expect = 0.19 Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 4/139 (2%) Frame = +2 Query: 74 IINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFN-NIGLYPKFLLAQITDKP 250 I G + +G A+V+A E+ V F ++ + G + + N G F L +TD Sbjct: 17 ITGGASGIGAALVRAFVEQ-GANVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTDTK 75 Query: 251 ALKKIADTIQMNHGSFDILINNT-EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQ--YLF 421 L+++ G DILINN D + D E K + S Q YL Sbjct: 76 QLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAYLV 135 Query: 422 PLLKDSGRVINVTNAYGHL 478 + G +IN ++ ++ Sbjct: 136 MKQRKQGVIINFSSNMAYI 154 >UniRef50_Q5AWR2 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 245 Score = 38.3 bits (85), Expect = 0.19 Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 6/148 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNI-LGLAIVKALSEKLNGTVYFTASDEEEGLKATENFN---NIGLYPK 220 MS + ++I+G N LG K L N + + D + KA + + N+ Sbjct: 1 MSSQTIVLISGANRGLGFEAAKCLVHLANYHIILGSRDLLKADKAADTLHALPNLKCSVS 60 Query: 221 FLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLL 400 + +TDK ++ I+ DIL+NN + + + + +D+ ++ Sbjct: 61 TVQLDVTDKSSITAAKSYIEATFSRLDILVNNAA-IYLLNPTSSVDALRASLDTNVIGVV 119 Query: 401 IVEQYLFPLLKDSG--RVINVTNAYGHL 478 + + L PLL+ S R+I V+++ G L Sbjct: 120 ALTEELLPLLRKSASPRLILVSSSNGSL 147 >UniRef50_Q1DT84 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 272 Score = 38.3 bits (85), Expect = 0.19 Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 3/133 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATEN-FNNIGLYPKFLL 229 ++ KVAI+ G + G AI A+ G +G ++ + + + + K + Sbjct: 61 LAGKVAIVTGGGSGFGAAI--AIRYAQEGAKVVIGDINIQGAESVSSQYPSSITFQKMDV 118 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN--TEDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 + D ++ I+ T+Q HG DIL+NN T + T EE + V D KS+ + Sbjct: 119 TSLADWQSV--ISQTVQA-HGHVDILVNNAGTTYRNKPSAEVTIEEFQRVFDVNVKSIFL 175 Query: 404 VEQYLFPLLKDSG 442 Q P L D G Sbjct: 176 ASQTFIPKLIDQG 188 >UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=23; Bacteria|Rep: Uncharacterized oxidoreductase ygcW - Escherichia coli (strain K12) Length = 261 Score = 38.3 bits (85), Expect = 0.19 Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 4/147 (2%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ K AI+ G + LG A AL+ K ++ + ++ G + E G+ F+ Sbjct: 15 SLKGKTAIVTGGNSGLGQAFAMALA-KAGANIFIPSFVKDNG-ETKEMIEKQGVEVDFMQ 72 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTE--DLKQCEDFPTYEEAKNVIDSKYKSL-- 397 IT + A +KI G+ DIL+NN L + DF + +ID + Sbjct: 73 VGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGR-ADWDPMIDVNLTAAFE 131 Query: 398 LIVEQYLFPLLKDSGRVINVTNAYGHL 478 L E + + SG++IN+ + + +L Sbjct: 132 LSYEAAKIMIPQKSGKIINICSLFSYL 158 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 38.3 bits (85), Expect = 0.19 Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKA-LSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 ++ K +I G + +G A V+A L ++ N V DE +G NN L+ F+ Sbjct: 3 LTDKTVLITGGASGIGYAAVQAFLGQQAN--VVVADIDEAQGEAMVRKENNDRLH--FVQ 58 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 ITD+ A + ++ G D+LINN Sbjct: 59 TDITDEAACQHAVESAVHTFGGLDVLINN 87 >UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD); n=2; Tribolium castaneum|Rep: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium castaneum Length = 479 Score = 37.9 bits (84), Expect = 0.25 Identities = 42/146 (28%), Positives = 66/146 (45%), Gaps = 6/146 (4%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASD--EEEGLKATENFNNIGLYPKFL 226 ++ KVA+I + +GL I K L NG T +D +E G KA + N + + Sbjct: 5 INNKVALISGAASGIGLTIAKELLR--NGLRGVTIADVNKELGEKALQEIENEFGSGRAI 62 Query: 227 LAQITDKPALKKIADTIQMNHGSF---DILINNTEDLKQCEDFPTYEEAKNVIDSKYKSL 397 +TD ++K D Q +F DIL+N L + E A NV + + L Sbjct: 63 FV-LTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLN--DSIWQQEIAINVNGTVHGIL 119 Query: 398 LIVEQYLFPLLKDS-GRVINVTNAYG 472 L +E Y+ DS G ++N ++ G Sbjct: 120 LALENYIPKYKTDSEGVIVNFSSIAG 145 >UniRef50_Q98K81 Cluster: Oxidoreductase of short-chain; n=4; Bacteria|Rep: Oxidoreductase of short-chain - Rhizobium loti (Mesorhizobium loti) Length = 279 Score = 37.9 bits (84), Expect = 0.25 Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 9/142 (6%) Frame = +2 Query: 236 ITDKPALKKIADTIQMNHGSFDILINNT--EDLKQCEDFPTYEEAKNVIDSKYKSLLIVE 409 +TDK A+ G D++INN E+ + +EA++ I++ L V Sbjct: 58 VTDKKAVDTAVAEAHKRFGRLDVVINNAGYGHFGAIEEV-SEQEARDQIETNVFGALWVT 116 Query: 410 QYLFPLLK--DSGRVINVT-----NAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEY 568 Q + P+++ SGR+I ++ NA+ L KW + L++E + + Sbjct: 117 QAVLPIMRAQRSGRIIQISSIGGVNAFASLGLYHASKWALEAFSQSLSIEVAE---FGIH 173 Query: 569 LRSLENGKFDKKWFSDDGKIAE 634 + +E G F W K+++ Sbjct: 174 VTLVEPGGFSTDWSGASAKVSK 195 >UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=14; Clostridia|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium tetani Length = 249 Score = 37.9 bits (84), Expect = 0.25 Identities = 31/144 (21%), Positives = 65/144 (45%), Gaps = 4/144 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ KVA+I + +G I L++K + D + + + G Y + + Sbjct: 6 LNGKVALITGASRGIGRGIAIELADKGACVIVNYRKDLKGAEETKKTIEERGGYCRIIKC 65 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEA--KNVIDSKYKSLLIV 406 ++ K + + I + G DILINN + + F EE N+I++ K + Sbjct: 66 DVSSYEDTKLMIEKIIRDFGKIDILINNA-GISKIGLFIDMEEEDWDNIINTNLKGVFNC 124 Query: 407 EQYLFPLL--KDSGRVINVTNAYG 472 + + P + + +G +IN+++ +G Sbjct: 125 SRNVLPYMIGEKNGVIINISSMWG 148 >UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nitrosospira multiformis ATCC 25196|Rep: Short-chain dehydrogenase/reductase SDR - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 247 Score = 37.9 bits (84), Expect = 0.25 Identities = 39/173 (22%), Positives = 67/173 (38%), Gaps = 2/173 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + KVAI+ + +G I + L V A D E G + A Sbjct: 5 LHNKVAIVTGASRGIGAEIARTLGGAGANVVVNYAKDREAAEAVCTAIQQAGAEAIAIKA 64 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDL--KQCEDFPTYEEAKNVIDSKYKSLLIV 406 +++ + ++ D DIL+NN L ++ D + +E V+D K + Sbjct: 65 DVSNSAEVCRLFDAAIERFQRLDILVNNAGVLLSRKMSDI-SDDEFDRVLDVNVKGVFYA 123 Query: 407 EQYLFPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEE 565 + L+D GRV+N+++ L + N A VEQ+ +F E Sbjct: 124 LREAAVRLEDGGRVVNLSSTVTRLM-LPN---YGAYAASKGAVEQLTRVFARE 172 >UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=4; Actinomycetales|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 37.9 bits (84), Expect = 0.25 Identities = 23/88 (26%), Positives = 40/88 (45%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ + AI+ + +GLA+ KA++ G V T+ +E A + + A Sbjct: 6 LTGRTAIVTGASRGIGLAVAKAIAAA-GGNVVLTSRSQESADAAAAQVGGTAIG---IAA 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINN 316 D+ A ++ D GS DIL+NN Sbjct: 62 HAVDEEAARRCVDVTLERFGSLDILVNN 89 >UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 275 Score = 37.9 bits (84), Expect = 0.25 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 1/89 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATE-NFNNIGLYPKFLL 229 ++ KVA++ G +GLA+ +A + + G A G +A G + Sbjct: 5 LADKVALVTGGARGIGLAVARAFARE--GAALVIADVNRAGAEAAAAGLAEAGGRAMAVA 62 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 + D ++ + + I HG DIL+NN Sbjct: 63 VDVADPASIAAMVEAILARHGRLDILVNN 91 >UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 254 Score = 37.9 bits (84), Expect = 0.25 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 1/89 (1%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFNNIGLYPKFLL 229 +S K+A++ G ++ GL A G V+ T D K E G + LL Sbjct: 4 LSGKIALVTGGASVPGLGSATAQRFAEEGAKVWLTDRDLAGAEKVAEGIRAAGGQARALL 63 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINN 316 +T++ ++ I+ G D+L+NN Sbjct: 64 HDVTNEAQWDEVFAAIEAEDGKLDVLVNN 92 >UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Petrotoga mobilis SJ95 Length = 248 Score = 37.9 bits (84), Expect = 0.25 Identities = 36/150 (24%), Positives = 67/150 (44%), Gaps = 5/150 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++QK+AI+ G+ +G I + ++ TV A DE ++ E + + A Sbjct: 3 LNQKIAIVTGGSRGIGKEISRNFIKE-GATVIAIAIDERPQIEENEKSDFPEDRFIYYQA 61 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTY---EEAKNVIDSKYKSLLI 403 ITD A+ +I I + DIL+NN K ++F E+ VI K + Sbjct: 62 DITDFNAISEIVTEIYNKYQKIDILVNNAGMAK--DNFLVIMKEEDFDKVIQVNLKGTFV 119 Query: 404 VEQYLFPLLKDS--GRVINVTNAYGHLSNI 487 + + + +++ G +I++ + G NI Sbjct: 120 MTKAVAKIMRKQKFGNIISMASVVGIEGNI 149 >UniRef50_A4A504 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 276 Score = 37.9 bits (84), Expect = 0.25 Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 7/147 (4%) Frame = +2 Query: 65 VAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGL-KATENFNNIGLYPKFLLAQIT 241 V I G +GL + +AL L G A EE L KA E G+ + + Sbjct: 8 VGFITGGAAGIGLGVGRALG--LKGMTLVLADVEENTLDKAAEELRAEGITVHTEVLDVR 65 Query: 242 DKPALKKIADTIQMNHGSFDILINNT---EDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQ 412 D A +++A+ HG + L NN + P ++ + V+D ++ + Sbjct: 66 DADAYREVAERTLATHGKVNFLFNNAGVGGGHTNAGETP-LQDWRWVVDVNLMGVVHGVE 124 Query: 413 YLFPLLKDSGR---VINVTNAYGHLSN 484 + P ++ G +IN + GH +N Sbjct: 125 FFLPAMRACGESCYIINTASLAGHTAN 151 >UniRef50_A3Q491 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 273 Score = 37.9 bits (84), Expect = 0.25 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 6/137 (4%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQIT 241 KVA++ +G I + + + V D + G + E+ +G F+ ++ Sbjct: 7 KVAVVTGAGKGIGRGIARRFARE-GAKVIAAELDRDAGKQVVEDIGELGGEGLFVQTDVS 65 Query: 242 DKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYK----SLLIVE 409 K ++ Q + G DIL+NN + D P + +++ K S+ Sbjct: 66 RKTDIEGAITAAQESFGGLDILVNNA--IALTPDVPLEYKTDEMLEQTMKVGLWSVWWGM 123 Query: 410 QYLFPLLK--DSGRVIN 454 Q FPL+K GR+IN Sbjct: 124 QTAFPLMKARGGGRIIN 140 >UniRef50_A2RHM7 Cluster: Oxidoreductase dltE; n=3; Lactococcus lactis|Rep: Oxidoreductase dltE - Lactococcus lactis subsp. cremoris (strain MG1363) Length = 261 Score = 37.9 bits (84), Expect = 0.25 Identities = 29/150 (19%), Positives = 67/150 (44%), Gaps = 5/150 (3%) Frame = +2 Query: 50 TMSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLL 229 T S +I GT+ +GL K +E N + +++ +EN G + Sbjct: 2 TFSGHTILITGGTSGIGLGFAKKFAELGNKVIIAARNEDRLNQILSENPTFSG-----FV 56 Query: 230 AQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYK-----S 394 + + D+ +L ++ + I N D+L+N ++ F + + + + + Sbjct: 57 SDVADENSLSQLVNFINENFPKLDLLMNCAGIMRAINLFEQADNSLGALTEEININLLGT 116 Query: 395 LLIVEQYLFPLLKDSGRVINVTNAYGHLSN 484 + + + +L L+ ++G VINV++ +L++ Sbjct: 117 IAVTQAFLEVLVANNGMVINVSSGLSNLAD 146 >UniRef50_Q4WGC3 Cluster: Short chain dehydrogenase/reductase family; n=16; Pezizomycotina|Rep: Short chain dehydrogenase/reductase family - Aspergillus fumigatus (Sartorya fumigata) Length = 358 Score = 37.9 bits (84), Expect = 0.25 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Frame = +2 Query: 62 KVAIIINGTNILGLAIVKALSEKLNGT-VYFTASDEEEGLKATENFN-NIGLYPKFLLAQ 235 KVA+I G + +GL +AL+ +NG VY T E+ + E + NI + A Sbjct: 83 KVALITGGGSGIGLMATQALA--VNGAKVYITGRTGEKLDRVVELYGKNIPGEIIPITAD 140 Query: 236 ITDKPALKKIADTIQMNHGSFDILINN 316 ITDK +++K+ I ILINN Sbjct: 141 ITDKKSIEKLVQEISSRETHLSILINN 167 >UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Short-chain dehydrogenase/reductase SDR - Halorubrum lacusprofundi ATCC 49239 Length = 263 Score = 37.9 bits (84), Expect = 0.25 Identities = 34/157 (21%), Positives = 69/157 (43%), Gaps = 6/157 (3%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 ++ +VA++ G +G AI ++ TV +A E + + G+ + + A Sbjct: 16 LTGRVAVVTGGGRGIGRAITLGMAAA-GATVVPSARTAAEVEAVADEARDFGVEARGITA 74 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT-----EDLKQCEDFPTYEEAKNVIDSKYKSL 397 +TD ++ + + I GS DIL+NN + L + + + +V+D + Sbjct: 75 DVTDDDDVEALVEEIVDAFGSLDILVNNAGFNPGDALGDPAEIES-DAVDSVLDVNLRGA 133 Query: 398 LIVEQYLFPLLKDS-GRVINVTNAYGHLSNIKNDKWI 505 + P LK++ G V+NV + G + K ++ Sbjct: 134 FRTLRAAGPHLKEAGGSVVNVASVAGEVGLPKQHPYV 170 >UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=18; Bacillales|Rep: Uncharacterized oxidoreductase yxbG - Bacillus subtilis Length = 273 Score = 37.9 bits (84), Expect = 0.25 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 4/149 (2%) Frame = +2 Query: 53 MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLA 232 + K A+I +G A + + + V ++++ + + G + Sbjct: 4 LENKTAVITGAATGIGQATAEVFANE-GARVIIGDINKDQMEETVDAIRKNGGQAESFHL 62 Query: 233 QITDKPALKKIADTIQMNHGSFDILINNT---EDLKQCEDFPTYEEAKNVIDSKYKSLLI 403 ++D+ ++K AD I+ G+ DIL NN ++ + ++P + +I + + Sbjct: 63 DVSDENSVKAFADQIKDACGTIDILFNNAGVDQEGGKVHEYPV-DLFDRIIAVDLRGTFL 121 Query: 404 VEQYLFPL-LKDSGRVINVTNAYGHLSNI 487 +YL PL L++ G +IN ++ G +++ Sbjct: 122 CSKYLIPLMLENGGSIINTSSMSGRAADL 150 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 676,821,958 Number of Sequences: 1657284 Number of extensions: 13522708 Number of successful extensions: 41937 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 39727 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 41838 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 59090914597 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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