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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmmt10i09
         (728 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p...   288   8e-77
UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 p...   250   3e-65
UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-...   198   1e-49
UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p...   196   6e-49
UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP000...   183   5e-45
UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1...   175   9e-43
UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chai...   174   2e-42
UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai...   165   1e-39
UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR...   147   3e-34
UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;...   137   3e-31
UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketor...   133   4e-30
UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:...   130   5e-29
UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; ...   129   6e-29
UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR...   127   2e-28
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR...   127   2e-28
UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ...   127   3e-28
UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Re...   126   4e-28
UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: A...   126   6e-28
UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR...   126   7e-28
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR...   124   2e-27
UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep...   123   5e-27
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R...   123   5e-27
UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR...   122   7e-27
UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici...   122   9e-27
UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena...   122   1e-26
UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...   121   2e-26
UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;...   121   2e-26
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR...   120   3e-26
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR...   120   4e-26
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre...   120   5e-26
UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r...   119   8e-26
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena...   118   1e-25
UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ...   117   3e-25
UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR...   117   3e-25
UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR...   116   4e-25
UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR...   116   4e-25
UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;...   116   4e-25
UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;...   116   6e-25
UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ...   116   6e-25
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR...   115   1e-24
UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; ...   115   1e-24
UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR...   114   2e-24
UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero...   114   2e-24
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b...   113   3e-24
UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep...   113   4e-24
UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh...   113   6e-24
UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...   112   7e-24
UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductas...   112   7e-24
UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   112   1e-23
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=...   111   1e-23
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR...   111   1e-23
UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase fam...   111   1e-23
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR...   111   1e-23
UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain de...   111   2e-23
UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR...   111   2e-23
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car...   110   3e-23
UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR...   110   3e-23
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma...   110   4e-23
UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...   110   4e-23
UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR...   109   5e-23
UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan...   109   5e-23
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc...   109   7e-23
UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR...   109   7e-23
UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|R...   109   9e-23
UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...   109   9e-23
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR...   109   9e-23
UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; ...   109   9e-23
UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase fam...   109   9e-23
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR...   109   9e-23
UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=...   108   1e-22
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   108   1e-22
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR...   108   1e-22
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;...   108   1e-22
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici...   108   2e-22
UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ...   108   2e-22
UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio bacte...   107   2e-22
UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR...   107   2e-22
UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   107   3e-22
UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR...   107   3e-22
UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR...   107   4e-22
UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...   106   5e-22
UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR...   106   5e-22
UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOH...   106   6e-22
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta...   106   6e-22
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec...   106   6e-22
UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M...   106   6e-22
UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/redu...   105   8e-22
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena...   105   8e-22
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu...   105   8e-22
UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR...   105   8e-22
UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reducta...   105   1e-21
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai...   105   1e-21
UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   105   1e-21
UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   105   1e-21
UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   105   1e-21
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR...   105   1e-21
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena...   104   2e-21
UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR...   104   2e-21
UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R...   104   2e-21
UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family memb...   104   2e-21
UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena...   104   3e-21
UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae...   104   3e-21
UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR...   104   3e-21
UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep:...   104   3e-21
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte...   104   3e-21
UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su...   103   3e-21
UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrob...   103   3e-21
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot...   103   3e-21
UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena...   103   3e-21
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb...   103   3e-21
UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenas...   103   4e-21
UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR...   103   4e-21
UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re...   103   4e-21
UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopire...   103   4e-21
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   103   4e-21
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...   103   4e-21
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR...   103   4e-21
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   103   4e-21
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho...   103   6e-21
UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya...   103   6e-21
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob...   103   6e-21
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR...   103   6e-21
UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;...   103   6e-21
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1...   102   8e-21
UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR...   102   8e-21
UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR...   102   8e-21
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR...   102   8e-21
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR...   102   8e-21
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR...   102   8e-21
UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ...   102   8e-21
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   102   1e-20
UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteri...   102   1e-20
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR...   102   1e-20
UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Microm...   102   1e-20
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR...   102   1e-20
UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...   101   1e-20
UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR...   101   1e-20
UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str...   101   1e-20
UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR...   101   1e-20
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR...   101   1e-20
UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR...   101   1e-20
UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR...   101   1e-20
UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;...   101   1e-20
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ...   101   1e-20
UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyc...   101   2e-20
UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano...   101   2e-20
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...   101   2e-20
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc...   101   2e-20
UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2; Pichi...   101   2e-20
UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein...   100   3e-20
UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR...   100   3e-20
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR...   100   3e-20
UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase...   100   3e-20
UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR...   100   3e-20
UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR...   100   3e-20
UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR...   100   3e-20
UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-20
UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR...   100   4e-20
UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha...   100   4e-20
UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR...   100   4e-20
UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR...   100   4e-20
UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular...   100   4e-20
UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    99   6e-20
UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6...    99   6e-20
UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Re...    99   6e-20
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    99   6e-20
UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=...    99   6e-20
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo...    99   6e-20
UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR...    99   6e-20
UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR...    99   6e-20
UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reducta...    99   6e-20
UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reducta...    99   6e-20
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    99   6e-20
UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl...   100   7e-20
UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1...   100   7e-20
UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1; Thermob...   100   7e-20
UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena...   100   7e-20
UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain de...   100   7e-20
UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1...   100   7e-20
UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobact...   100   7e-20
UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   100   7e-20
UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR...   100   7e-20
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...   100   7e-20
UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Ac...    99   1e-19
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=...    99   1e-19
UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-...    99   1e-19
UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder...    99   1e-19
UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|...    99   1e-19
UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_A4T6Z1 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...    99   1e-19
UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_A0GDY0 Cluster: Short-chain dehydrogenase/reductase SDR...    99   1e-19
UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...    99   1e-19
UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb...    99   1e-19
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O...    98   2e-19
UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain dehydrogena...    98   2e-19
UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_Q3WHY3 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacte...    98   2e-19
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho...    98   2e-19
UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ...    98   2e-19
UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    98   2e-19
UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...    98   2e-19
UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici...    98   2e-19
UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: G...    98   2e-19
UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    98   2e-19
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR...    98   2e-19
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr...    98   2e-19
UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT...    97   3e-19
UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    97   3e-19
UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|...    97   3e-19
UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=...    97   3e-19
UniRef50_A2W1T9 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A0XC03 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_A0JX96 Cluster: Short-chain dehydrogenase/reductase SDR...    97   3e-19
UniRef50_Q2UFW9 Cluster: Dehydrogenases with different specifici...    97   3e-19
UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    97   4e-19
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    97   4e-19
UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    97   4e-19
UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR...    97   4e-19
UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR...    97   4e-19
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR...    97   4e-19
UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    97   4e-19
UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR...    97   5e-19
UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma p...    97   5e-19
UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR...    97   5e-19
UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholder...    97   5e-19
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    97   5e-19
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR...    97   5e-19
UniRef50_A4M3J4 Cluster: Short-chain dehydrogenase/reductase SDR...    97   5e-19
UniRef50_Q9PDC2 Cluster: Pteridine reductase 1; n=11; Xanthomona...    96   7e-19
UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR...    96   7e-19
UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier prot...    96   7e-19
UniRef50_A6GPQ6 Cluster: Short chain dehydrogenase; n=1; Limnoba...    96   7e-19
UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogena...    96   7e-19
UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:...    96   9e-19
UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    96   9e-19
UniRef50_Q983U4 Cluster: Putative dehydrogenase; n=1; Mesorhizob...    96   9e-19
UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_Q2C7C6 Cluster: Oxidoreductase, short-chain dehydrogena...    96   9e-19
UniRef50_Q1GHX9 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni...    96   9e-19
UniRef50_Q03RV5 Cluster: 3-oxoacyl-acyl carrier protein reductas...    96   9e-19
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_A5D4R4 Cluster: Dehydrogenases with different specifici...    96   9e-19
UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter...    96   9e-19
UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola...    96   9e-19
UniRef50_A1WWM8 Cluster: Short-chain dehydrogenase/reductase SDR...    96   9e-19
UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ...    96   9e-19
UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehy...    95   1e-18
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -...    95   1e-18
UniRef50_Q8YJQ0 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT...    95   1e-18
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll...    95   1e-18
UniRef50_Q4FPW9 Cluster: Possible Short-chain dehydrogenase/redu...    95   1e-18
UniRef50_Q3IVH6 Cluster: Short-chain dehydrogenase/reductase SDR...    95   1e-18
UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ...    95   1e-18
UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR...    95   1e-18
UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho...    95   1e-18
UniRef50_Q0SJP6 Cluster: Probable 3-oxoacyl-[acyl-carrier protei...    95   1e-18
UniRef50_Q0FYP2 Cluster: Probable oxidoreductase protein, short-...    95   1e-18
UniRef50_Q0FPS1 Cluster: Probable dehydrogenase; n=1; Roseovariu...    95   1e-18
UniRef50_A5VBH4 Cluster: Short-chain dehydrogenase/reductase SDR...    95   1e-18
UniRef50_A5CY54 Cluster: Dehydrogenases with different specifici...    95   1e-18
UniRef50_A1SIL0 Cluster: Short-chain dehydrogenase/reductase SDR...    95   1e-18
UniRef50_Q8YSW6 Cluster: Oxidoreductase; n=3; Nostocaceae|Rep: O...    95   2e-18
UniRef50_Q62E80 Cluster: Acetoacetyl-CoA reductase; n=60; Proteo...    95   2e-18
UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q6W1L9 Cluster: Short chain dehydrogenase; n=2; Rhizobi...    95   2e-18
UniRef50_Q3W9G7 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q3W2E5 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=...    95   2e-18
UniRef50_A5UX97 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein...    95   2e-18
UniRef50_A1VQU4 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo...    95   2e-18
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=...    95   2e-18
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=...    95   2e-18
UniRef50_Q9BY49 Cluster: Peroxisomal trans-2-enoyl-CoA reductase...    95   2e-18
UniRef50_Q8YHX9 Cluster: SHORT-CHAIN DEHYDROGENASE; n=10; Bacter...    95   2e-18
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc...    95   2e-18
UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill...    95   2e-18
UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    95   2e-18
UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reduc...    95   2e-18
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    95   2e-18
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q398J5 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q395K9 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q2S4K7 Cluster: Oxidoreductase, short chain dehydrogena...    95   2e-18
UniRef50_Q676G3 Cluster: Probable short-chain dehydrogenase; n=1...    95   2e-18
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=...    95   2e-18
UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q1ASH3 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q18YK8 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    95   2e-18
UniRef50_Q08XI3 Cluster: 2-(S)-hydroxypropyl-CoM dehydrogenase; ...    95   2e-18
UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_A5V529 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    95   2e-18
UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR...    95   2e-18
UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family memb...    95   2e-18
UniRef50_Q83BJ4 Cluster: Oxidoreductase, short chain dehydrogena...    94   3e-18
UniRef50_Q1NA92 Cluster: Gluconate 5-dehydrogenase; n=1; Sphingo...    94   3e-18
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR...    94   3e-18
UniRef50_Q12JI9 Cluster: Short-chain dehydrogenase/reductase SDR...    94   3e-18
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR...    94   3e-18
UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogena...    94   3e-18
UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR...    94   3e-18
UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena...    94   3e-18
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR...    94   3e-18
UniRef50_Q8ZYG0 Cluster: Short chain dehydrogenase; n=2; Pyrobac...    94   3e-18
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    94   3e-18
UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus eryth...    94   4e-18
UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    94   4e-18
UniRef50_Q1VSS0 Cluster: Gluconate 5-dehydrogenase, putative; n=...    94   4e-18
UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida...    94   4e-18
UniRef50_Q0K556 Cluster: Short chain dehydrogenase; n=1; Ralston...    94   4e-18
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR...    94   4e-18
UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR...    94   4e-18
UniRef50_A5G1R2 Cluster: Short-chain dehydrogenase/reductase SDR...    94   4e-18
UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR...    94   4e-18
UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR...    94   4e-18
UniRef50_P52037 Cluster: Uncharacterized oxidoreductase ygfF; n=...    94   4e-18
UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductas...    93   5e-18
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    93   5e-18
UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR...    93   5e-18
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR...    93   5e-18
UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;...    93   5e-18
UniRef50_A5I7D8 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n...    93   5e-18
UniRef50_A3U1B5 Cluster: Putative short chain dehydrogenase; n=1...    93   5e-18
UniRef50_Q9URX0 Cluster: Short chain dehydrogenase; n=1; Schizos...    93   5e-18
UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat...    93   6e-18
UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena...    93   6e-18
UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;...    93   6e-18
UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena...    93   6e-18
UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain dehydrogena...    93   6e-18
UniRef50_Q2J935 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill...    93   6e-18
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc...    93   6e-18
UniRef50_A5VE69 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_A5V448 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    93   6e-18
UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;...    93   6e-18
UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like;...    93   6e-18
UniRef50_A7RYX9 Cluster: Predicted protein; n=1; Nematostella ve...    93   6e-18
UniRef50_Q9HT49 Cluster: Probable short-chain dehydrogenase; n=5...    93   8e-18
UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=...    93   8e-18
UniRef50_Q89FM8 Cluster: Dehydrogenase; n=1; Bradyrhizobium japo...    93   8e-18
UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter...    93   8e-18
UniRef50_Q5MPN9 Cluster: Hypothetical 3-oxoacyl-acyl carrier pro...    93   8e-18
UniRef50_Q1LDG6 Cluster: Short-chain dehydrogenase/reductase SDR...    93   8e-18
UniRef50_Q128G0 Cluster: Short-chain dehydrogenase/reductase SDR...    93   8e-18
UniRef50_A5V6V5 Cluster: Short-chain dehydrogenase/reductase SDR...    93   8e-18
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    93   8e-18
UniRef50_A3VA26 Cluster: Short-chain dehydrogenase/reductase SDR...    93   8e-18
UniRef50_A1UM67 Cluster: Short-chain dehydrogenase/reductase SDR...    93   8e-18
UniRef50_A0VRG5 Cluster: Short-chain dehydrogenase/reductase SDR...    93   8e-18
UniRef50_Q21929 Cluster: Probable L-xylulose reductase; n=3; Bil...    93   8e-18
UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    93   8e-18
UniRef50_UPI0000E252C4 Cluster: PREDICTED: similar to Dehydrogen...    92   1e-17
UniRef50_Q3WFB3 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena...    92   1e-17
UniRef50_A4W910 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_A1SNX1 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_A0GD21 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_Q0GJJ3 Cluster: 11-beta-hydroxysteroid dehydrogenase-li...    92   1e-17
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula...    92   1e-17
UniRef50_Q9RJU5 Cluster: Probable oxidoreductase; n=1; Streptomy...    92   1e-17
UniRef50_Q62GI3 Cluster: Oxidoreductase, short-chain dehydrogena...    92   1e-17
UniRef50_Q602S5 Cluster: Oxidoreductase, short chain dehydrogena...    92   1e-17
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    92   1e-17
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_Q0I7J4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    92   1e-17
UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ...    92   1e-17
UniRef50_A5EDQ3 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    92   1e-17
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro...    92   1e-17
UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR...    92   1e-17
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam...    92   1e-17
UniRef50_A2TF13 Cluster: 11-beta short-chain dehydrogenase reduc...    92   1e-17
UniRef50_Q9KEP9 Cluster: Dehydrogenase/reductase family; n=12; B...    91   2e-17
UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogena...    91   2e-17
UniRef50_Q1RS55 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    91   2e-17
UniRef50_A4XEF9 Cluster: Short-chain dehydrogenase/reductase SDR...    91   2e-17
UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR...    91   2e-17
UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta...    91   2e-17
UniRef50_A0LVM3 Cluster: Short-chain dehydrogenase/reductase SDR...    91   2e-17
UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    91   2e-17
UniRef50_Q9ANA1 Cluster: ID403; n=2; Proteobacteria|Rep: ID403 -...    91   3e-17
UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    91   3e-17
UniRef50_Q5LMF4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    91   3e-17
UniRef50_Q3IVC8 Cluster: Short-chain alcohol dehydrogenases; n=2...    91   3e-17
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac...    91   3e-17
UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_Q2N2P3 Cluster: 3-oxoacyl-carrier-protein reductase; n=...    91   3e-17
UniRef50_Q1ARR8 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_Q0AT35 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ...    91   3e-17
UniRef50_A1UD00 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_Q0CF34 Cluster: Putative uncharacterized protein; n=1; ...    91   3e-17
UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogena...    91   3e-17
UniRef50_P50199 Cluster: Gluconate 5-dehydrogenase; n=35; Bacter...    91   3e-17
UniRef50_P80869 Cluster: Glucose 1-dehydrogenase 2; n=39; Bacill...    91   3e-17
UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al...    91   3e-17
UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    91   3e-17
UniRef50_Q53W85 Cluster: Oxidoreductase, short-chain dehydrogena...    91   3e-17
UniRef50_Q2CHI2 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_Q1NHB1 Cluster: Oxidoreductase; n=1; Sphingomonas sp. S...    91   3e-17
UniRef50_Q1M6N2 Cluster: Putative short-chain dehydrogenase/redu...    91   3e-17
UniRef50_Q08Z99 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    91   3e-17
UniRef50_A6EBP7 Cluster: Short chain dehydrogenase; n=1; Pedobac...    91   3e-17
UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena...    91   3e-17
UniRef50_A1R756 Cluster: Putative 3-oxoacyl-(Acyl carrier protei...    91   3e-17
UniRef50_Q8YDW1 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT...    90   4e-17
UniRef50_Q8R6S8 Cluster: Dehydrogenases with different specifici...    90   4e-17
UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR...    90   4e-17
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ...    90   4e-17
UniRef50_A4FJJ0 Cluster: Short-chain dehydrogenase/reductase SDR...    90   4e-17
UniRef50_A1SCT9 Cluster: Short-chain dehydrogenase/reductase SDR...    90   4e-17
UniRef50_A0Z805 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    90   4e-17
UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR...    90   4e-17
UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=1...    90   4e-17
UniRef50_A2QKU0 Cluster: Contig An05c0050, complete genome; n=3;...    90   4e-17
UniRef50_Q9RWD9 Cluster: Oxidoreductase, short-chain dehydrogena...    90   6e-17
UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li...    90   6e-17
UniRef50_Q8U673 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=...    90   6e-17
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid...    90   6e-17
UniRef50_Q28RW9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    90   6e-17
UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu...    90   6e-17
UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR...    90   6e-17
UniRef50_A6PKN4 Cluster: Short-chain dehydrogenase/reductase SDR...    90   6e-17
UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR...    90   6e-17
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    90   6e-17
UniRef50_A3JX84 Cluster: Short chain dehydrogenase; n=5; Alphapr...    90   6e-17
UniRef50_A2TZE3 Cluster: Putative dehydrogenase; n=1; Polaribact...    90   6e-17
UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=...    90   6e-17
UniRef50_A7D7F1 Cluster: Short-chain dehydrogenase/reductase SDR...    90   6e-17
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    89   8e-17
UniRef50_Q8UAP0 Cluster: Dehydrogenase; n=7; Bacteria|Rep: Dehyd...    89   8e-17
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena...    89   8e-17
UniRef50_Q7WPD3 Cluster: Probable short-chain dehydrogenase; n=1...    89   8e-17
UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;...    89   8e-17
UniRef50_Q39DX6 Cluster: Short-chain dehydrogenase/reductase SDR...    89   8e-17
UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco...    89   8e-17
UniRef50_Q0LZB7 Cluster: NAD-dependent epimerase/dehydratase:Sho...    89   8e-17
UniRef50_Q03ND1 Cluster: 3-oxoacyl-acyl carrier protein reductas...    89   8e-17
UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR...    89   8e-17
UniRef50_A6W647 Cluster: Short-chain dehydrogenase/reductase SDR...    89   8e-17
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR...    89   8e-17
UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    89   8e-17
UniRef50_A2RBM4 Cluster: Contig An19c0010, complete genome; n=6;...    89   8e-17

>UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p -
           Drosophila melanogaster (Fruit fly)
          Length = 269

 Score =  288 bits (707), Expect = 8e-77
 Identities = 147/241 (60%), Positives = 171/241 (70%), Gaps = 2/241 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--I 185
           MNFAGKVV                 +K GA L+L GRNVENL+KV+ +C K + +    +
Sbjct: 14  MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALV 73

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365
             D+ KE+D ++I  +T+  YGKLDVLVNNAGIIETGTIE TSL QYDR+MNTN+R+IY+
Sbjct: 74  VGDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYH 133

Query: 366 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           LTMLA P L+++KG         GIRSFPGVLAYNISK  VDQFTRCVALELA KGVRVN
Sbjct: 134 LTMLATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVN 193

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
           CVNPGV +T L  RGG+  E Y  FLE +K THALGRPG   EVAA IAFLASD AS  T
Sbjct: 194 CVNPGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFST 253

Query: 726 G 728
           G
Sbjct: 254 G 254


>UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC79752 protein -
           Strongylocentrotus purpuratus
          Length = 303

 Score =  250 bits (612), Expect = 3e-65
 Identities = 121/216 (56%), Positives = 160/216 (74%), Gaps = 2/216 (0%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           S LGA+L L GR   NL +    C +  +   L++T +L   S  + ++++ ++ YGKLD
Sbjct: 73  SHLGARLVLAGRKEANLMRTKDSCMQTGNEEALTVTGELRDGSYRKHLVEQAMEEYGKLD 132

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           +LVNNAG+I  G+IEN+SL  YD +M+ NVRS+++LT LAVPHL+E+KG         G+
Sbjct: 133 ILVNNAGVISLGSIENSSLEDYDTMMDVNVRSVFHLTSLAVPHLIETKGNIVNVSSVNGL 192

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
           R+F GVL+Y +SKA++D FTRC ALELAPKGVRVN VNPGV +TELQ+RGGLS+E YA F
Sbjct: 193 RAFAGVLSYCMSKAALDHFTRCTALELAPKGVRVNSVNPGVTITELQKRGGLSDEAYANF 252

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           LER+K THALGRPG+  E+A +IAFLASD +S ITG
Sbjct: 253 LERSKMTHALGRPGEASEIAESIAFLASDASSFITG 288


>UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small
           subunit-like protein; n=3; Bilateria|Rep: U2 snRNP
           splicing factor small subunit-like protein - Schistosoma
           mansoni (Blood fluke)
          Length = 265

 Score =  198 bits (482), Expect = 1e-49
 Identities = 106/224 (47%), Positives = 141/224 (62%), Gaps = 10/224 (4%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFAST----------LSITADLTKESDIEKIIKKT 236
           +KLGA ++L  R+   L++  + C + +            L I ADL +  +IEK  +  
Sbjct: 27  AKLGACVALIARDKSRLEETRQACIQISHPDVYEKHKEPFLCIEADLAETCEIEKAYRLA 86

Query: 237 IDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 416
           I+H+ +LD+LVNNAG +   T E+ ++A+Y+ LM  NV +   LT LA+P L  SKG   
Sbjct: 87  INHFHQLDILVNNAGCMIRDTAESFNVAEYEHLMKVNVTAAITLTNLAIPDLAASKGSIV 146

Query: 417 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
                 G RSFPGV++Y ISKA++DQFTRC AL+LAPKG+RVN V P VI+TEL RR G+
Sbjct: 147 NVSSVCGKRSFPGVMSYCISKAALDQFTRCTALDLAPKGIRVNSVYPAVIVTELHRRSGM 206

Query: 597 SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           SE  Y  FL R  ETHALGR G  +EVA  IAFL+S  +S  TG
Sbjct: 207 SENDYEKFLSRANETHALGRTGTVEEVAQAIAFLSSSASSFTTG 250


>UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p -
           Drosophila melanogaster (Fruit fly)
          Length = 255

 Score =  196 bits (477), Expect = 6e-49
 Identities = 100/239 (41%), Positives = 147/239 (61%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           M+ + KVV                L++ GA L+L GRNV NL+   K   K      + A
Sbjct: 5   MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSL-KGTQAEIVVA 63

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D+TK++D   I+++T+  +G++DVLVNNAGI+  G + +  + ++D ++NTN+R +  LT
Sbjct: 64  DVTKDADA--IVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLT 121

Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551
              +PHLL++KG         GIR F G L+Y +SKA++DQFT+ VALE+AP+GVRVN V
Sbjct: 122 KAVLPHLLKTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSV 181

Query: 552 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           NPG ++T + R  G+ +E+Y   L+R   +H +GR G   EVA  +AFLAS  AS  TG
Sbjct: 182 NPGFVVTNIHRNIGIVDEEYNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTG 240


>UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to
           ENSANGP00000021339; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to ENSANGP00000021339
           - Strongylocentrotus purpuratus
          Length = 242

 Score =  183 bits (445), Expect = 5e-45
 Identities = 93/219 (42%), Positives = 139/219 (63%), Gaps = 5/219 (2%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSITADLTKESDIEKIIKKTIDHYGK 254
           + LG +L+LTGRN+E LQ+V+ +C +        L I AD   E+D+++  ++TI  + +
Sbjct: 6   ASLGCRLALTGRNMETLQEVTNECIRRGLDKNKILMIQADFELEADVKRTAEETIQKFNQ 65

Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 434
           +DVLVNNAG++  G++E  SL  +D++   NVR+   LT L  P L+++KG         
Sbjct: 66  IDVLVNNAGVLTAGSVETVSLESFDKIFAVNVRAPLQLTQLLAPQLIKTKGTVVNVSSVV 125

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GLSEEQY 611
           G  S P  L Y++SK ++D  TR +A ELAP GVRVN VNPG I+T + +R  G+++E+ 
Sbjct: 126 GKVSMPDFLIYSMSKTALDHMTRSIAEELAPHGVRVNAVNPGAIVTPIIKRSFGMTDEET 185

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A F E+ K  HA+ R G  DEV+ TIAF+AS+ +S  TG
Sbjct: 186 AQFFEKMKRNHAMRRTGTVDEVSRTIAFMASNDSSFTTG 224


>UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1;
           Spodoptera littoralis|Rep: 3-dehydroecdysone
           3alpha-reductase - Spodoptera littoralis (Egyptian
           cotton leafworm)
          Length = 249

 Score =  175 bits (426), Expect = 9e-43
 Identities = 95/240 (39%), Positives = 142/240 (59%), Gaps = 3/240 (1%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITAD 194
           FA KVV                  K GA ++  GRN   L++V   C +  A+ L+I AD
Sbjct: 2   FANKVVLVTGGSSGIGAATVEAFVKEGASVAFVGRNQAKLKEVESRCQQHGANILAIKAD 61

Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLT 371
           ++K+ + + I+++T+D +GKLDVLVNNAGI+   ++ E T +  +D  MNTN+R +  +T
Sbjct: 62  VSKDEEAKIIVQQTVDKFGKLDVLVNNAGILRFASVLEPTLIQTFDETMNTNLRPVVLIT 121

Query: 372 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
            LA+PHL+ +KG           I   PG+++Y++SKA++D FT+  ALELAP GVRVN 
Sbjct: 122 SLAIPHLIATKGSIVNVSSILSTIVRIPGIMSYSVSKAAMDHFTKLAALELAPSGVRVNS 181

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           VNPG +LT++    G S +     LE T     LG+  + +E+A  I +LASD A ++TG
Sbjct: 182 VNPGPVLTDIAAGSGFSPD----LLEDTGAHTPLGKAAQSEEIADMIVYLASDKAKSVTG 237


>UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chain
           dehydrogenase; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to short-chain dehydrogenase -
           Strongylocentrotus purpuratus
          Length = 269

 Score =  174 bits (424), Expect = 2e-42
 Identities = 103/242 (42%), Positives = 138/242 (57%), Gaps = 5/242 (2%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 185
           F GKVV                 +  GA L+L GR+   L+K ++DC          L+I
Sbjct: 4   FVGKVVLITGASSGIGAETAVHFAAEGAGLALVGRDEGRLEKTAQDCMAKGLAKDKVLTI 63

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIY 362
            AD+  E D+++I++ TI ++G+LDVLVNNAG  +   + + T +  +D L+  NVRS+ 
Sbjct: 64  KADMCVEEDVKRIVESTITYFGRLDVLVNNAGQAKLDLLRSETVMENFDDLLKLNVRSVV 123

Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
            LT LAVPHL+ SKG         G R      +YNI +A+ DQFTRC A++LAPKGVRV
Sbjct: 124 QLTNLAVPHLITSKGSVVNVSSLAGKRVAHMSFSYNILRAATDQFTRCCAVDLAPKGVRV 183

Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722
           N VNPG I T L    G+  EQ     E   + H LGR G+P +VA+ I FLAS+ AS I
Sbjct: 184 NAVNPGAIKTPLLTGFGIPAEQIE---EVCAKMHPLGRIGQPTDVASAIKFLASNAASFI 240

Query: 723 TG 728
           TG
Sbjct: 241 TG 242


>UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chain
           dehydrogenase; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to short-chain dehydrogenase -
           Strongylocentrotus purpuratus
          Length = 250

 Score =  165 bits (400), Expect = 1e-39
 Identities = 89/218 (40%), Positives = 130/218 (59%), Gaps = 4/218 (1%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSITADLTKESDIEKIIKKTIDHYGK 254
           +++G +L+LTGR+ E L+ V K C +   +    L I ADLT++ D+E+I  KTI+ +G+
Sbjct: 24  AEIGCRLALTGRDAEKLKDVGKSCCERGLSEKEILVIAADLTEDEDLERIFSKTIEKFGR 83

Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 434
           LD+L+NNAG    G   +  +  +D +M  N+RS  YL+ LA+P+L ESKG         
Sbjct: 84  LDILINNAGRPAKGRFHDLQMTFFDDVMRLNLRSAIYLSKLAIPYLKESKGCVVNMSSVA 143

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
              +      Y+ISK ++DQFT+ +A+EL P GVRVN +NPGVILT L R  G S+ Q  
Sbjct: 144 SKTTCDYNPTYSISKVALDQFTKSLAVELGPYGVRVNSLNPGVILTPLYRNLGKSDAQVI 203

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +   +K  H +GR G  DEV     +L SD +  +TG
Sbjct: 204 TW---SKSMHPIGRHGTVDEVVKATEYLVSDASRCVTG 238


>UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Pasteurellaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Actinobacillus
           succinogenes 130Z
          Length = 248

 Score =  147 bits (356), Expect = 3e-34
 Identities = 82/215 (38%), Positives = 119/215 (55%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           ++K GA + + GRN   L++     ++  +   + AD+ K  DI +++ +  + +GKLD+
Sbjct: 26  MAKDGANVVIIGRNEATLEE---SAEQHENITYLVADVLKSEDIARVLTEIQEEFGKLDI 82

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
           +VNNAGI     IEN +LA +DR    NVR++  +T  A+P+L  SKG            
Sbjct: 83  VVNNAGIAPMTPIENINLADFDRTFALNVRAVIDVTAQAIPYLKASKGNIVNIISGLVHN 142

Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623
             PG   Y  SKA+V   TR  A ELA  G+RVNCV+ G   T +    G SEEQ  A+ 
Sbjct: 143 PMPGNCIYTASKAAVLSLTRTWAKELAAYGIRVNCVSVGAANTSIHDALGFSEEQMNAYK 202

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           +       LGR G+PDE+A  +AFLAS+ A  +TG
Sbjct: 203 QAVSSAVPLGRFGEPDEIAPIVAFLASEHARYVTG 237


>UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;
           n=5; Caenorhabditis|Rep: Dehydrogenases, short chain
           protein 14 - Caenorhabditis elegans
          Length = 279

 Score =  137 bits (331), Expect = 3e-31
 Identities = 86/250 (34%), Positives = 136/250 (54%), Gaps = 13/250 (5%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 185
           F+GKV                 L++ GA++++TGRN + L++  ++  K        LSI
Sbjct: 4   FSGKVALVTGSSNGIGRATAVLLAQEGAKVTITGRNADRLEETRQEILKSGVPEDHVLSI 63

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIE-NTSLAQYDRLMNTNVR 353
             DL  E   ++++  TI  +G+LD+LVNNAG     + G +  +  ++ YDR+M  N+R
Sbjct: 64  ATDLATEKGQDELVNSTIQKFGRLDILVNNAGAAFNDDQGRVGVDQDVSVYDRIMQINMR 123

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
           S+  LT  A  HL+++KG          G ++ P  + Y +SKA++DQ+TR  A++L   
Sbjct: 124 SVVTLTQKAKEHLVKAKGEVVNVSSIGAGPQAQPTFMYYAMSKAALDQYTRSAAIDLIQY 183

Query: 531 GVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701
           GVRVN V+PG ++T      G+     E+Y  F+E  KE    G+ G+P ++A  IAFLA
Sbjct: 184 GVRVNSVSPGAVVTGFGEAMGMPADMHEKYGHFMESRKECIPCGKMGQPIDIANIIAFLA 243

Query: 702 S-DLASNITG 728
              L+S I G
Sbjct: 244 DRKLSSYIIG 253


>UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep:
           Ketoreductase - Symbiobacterium thermophilum
          Length = 241

 Score =  133 bits (322), Expect = 4e-30
 Identities = 79/214 (36%), Positives = 115/214 (53%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
           ++ GA++ +TGR  E L++             +TAD+T  SD  +++++    +G++DV+
Sbjct: 19  ARRGAKVLITGRRPEPLRETEAAAPGIRG---VTADVTVASDARRVVEEAAKLWGRIDVV 75

Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 446
           VNNAG+  +G  E        +L  TNV     L   A+P L ES+G         G ++
Sbjct: 76  VNNAGMFASGPFEKVGAETAAQLFATNVFGPINLVREALPWLKESRGAIINVSSTYGHKA 135

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626
              V  Y  SKA++D  TRC ALELAP G+RVN V PG   T +  R GL E+  A+  E
Sbjct: 136 AANVAHYAASKAALDHLTRCWALELAPYGIRVNAVAPGPTETPILSRSGLPEDVVASIKE 195

Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             K    LGR G+PD+VAA I  LA+  +  +TG
Sbjct: 196 AEKRQIPLGRRGEPDDVAAWIVALAAPGSHWLTG 229


>UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:
           Oxidoreductase - Streptomyces echinatus
          Length = 295

 Score =  130 bits (313), Expect = 5e-29
 Identities = 75/213 (35%), Positives = 118/213 (55%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ + GR    L++ ++         ++ AD+T     + ++   ++ +G++DVLVNN
Sbjct: 74  GARVLVVGRTPGTLEETARH---HPGIRALPADITAPDGPDTVVSAALERFGRIDVLVNN 130

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX--GIRSF 449
           A +   GT++    A  D  + TN+R+   LT  A+P L +S G           G R++
Sbjct: 131 AALGIAGTLDTLDPADLDAQLATNLRAPMLLTRRALPALEKSSGTVVNLSTAGSLGRRAW 190

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
           PG+  Y  +K ++D  TR  A+ELAP+G+RV  + PGVI T +  R G SEEQYAAFL+ 
Sbjct: 191 PGMSVYGATKTALDFLTRTWAVELAPRGIRVVGLAPGVIDTGMATRNGASEEQYAAFLDG 250

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +     GR G+P+E+A  +A LA  LA    G
Sbjct: 251 IRSRVPAGRVGRPEEIAWWVARLADPLAGYAHG 283


>UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1;
           Rhizobium sp. NGR234|Rep: Putative uncharacterized
           protein - Rhizobium sp. (strain NGR234)
          Length = 244

 Score =  129 bits (312), Expect = 6e-29
 Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 1/184 (0%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
           SI+ D+T E +  + I K +   G+LD+L+NNAG+ E+G++E TSL Q+ RL++TN+ SI
Sbjct: 49  SISLDVTDEGNWTRAISKVVSAAGRLDILINNAGVRESGSVEETSLEQWRRLIDTNLTSI 108

Query: 360 YYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           +     AVP + ++  G         GIR    ++AY+ SK+ +   T  +AL+LA   +
Sbjct: 109 FLGCRAAVPAIRQAGGGAIVNVGSITGIRGTENMVAYSASKSGITSMTSSLALDLASDNI 168

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
           RVN V P  I T +      S +   A        H +GR G+PDEVA+ IAFLASD +S
Sbjct: 169 RVNAVCPAAIRTRMVTNWLNSSQDTDAAEAAVLAKHPIGRIGRPDEVASVIAFLASDDSS 228

Query: 717 NITG 728
            +TG
Sbjct: 229 FMTG 232


>UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Clostridium beijerinckii NCIMB 8052
          Length = 246

 Score =  127 bits (307), Expect = 2e-28
 Identities = 77/240 (32%), Positives = 123/240 (51%), Gaps = 2/240 (0%)
 Frame = +3

Query: 15  NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSIT 188
           N  GKV                 LS LGA++ +    N    ++V ++  K     ++I 
Sbjct: 3   NLEGKVAIITGASRGIGSAIARQLSALGAKVVVNYSNNAVKAEEVVEEITKSGEQAVAIK 62

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           AD++   D+EK+  +TI  +G++D+L+NNAG+I    + + +  ++D+L N NV+  Y+ 
Sbjct: 63  ADVSNIKDVEKLFSETITKFGRVDILINNAGVILYKLLSDVTEEEFDKLFNINVKGTYFA 122

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
              A+ H +E+ G             FP    Y  +K +V+Q TR +A E  PK + +N 
Sbjct: 123 CQQAMKH-MENNGRIINFSTSVVGSMFPTYSVYAATKGAVEQITRQLAKEFGPKKITINA 181

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           V PG I TEL   G   E+     +E  ++ ++ GR G+PD++A TI FL SD A  ITG
Sbjct: 182 VAPGPINTELFNVGKTDEQ-----IEAIRQMNSFGRIGEPDDIANTIEFLVSDKAQWITG 236


>UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Candidatus Nitrosopumilus maritimus
           SCM1|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Candidatus Nitrosopumilus maritimus SCM1
          Length = 269

 Score =  127 bits (307), Expect = 2e-28
 Identities = 73/242 (30%), Positives = 135/242 (55%), Gaps = 3/242 (1%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           ++ +GKV                 LS+ GA +++TG+  E L+KVS +    +++ +I A
Sbjct: 23  LSLSGKVALVTGGSRGIGFATAKVLSENGANVAITGKVQERLEKVSSE---ISNSFAIVA 79

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368
           D+ K  D++  IKK ++ +G+LD+LVNNAG+  +   +      +++ +++ N+   + +
Sbjct: 80  DVRKTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRV 139

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALELAPKGVRV 542
           T  A+PHL ++ G         G++++ G    AY+ +KA++   T+C ALE +   +RV
Sbjct: 140 TKEAIPHLQKTSGSIINISSDAGLKAYQGFNADAYSATKAALIVLTKCWALEYSKDKIRV 199

Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722
           NC+ PGV+ T++  +  +  ++   F+      H LGR G+P+EVA  + + ASD A+  
Sbjct: 200 NCICPGVVDTDM-TKPFVKTQKDRDFM---NAEHPLGRIGEPEEVAKAVLYFASDDAAWT 255

Query: 723 TG 728
           TG
Sbjct: 256 TG 257


>UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1;
           Sarcoptes scabiei type suis|Rep: Putative
           uncharacterized protein - Sarcoptes scabiei type suis
          Length = 304

 Score =  127 bits (306), Expect = 3e-28
 Identities = 80/245 (32%), Positives = 127/245 (51%), Gaps = 7/245 (2%)
 Frame = +3

Query: 15  NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS----TLS 182
           +F+GKV                  ++ GA++ +TGR+   L+KV+ + +K        L 
Sbjct: 38  DFSGKVALVTGSSSGIGAAIALQFAQYGAKVCITGRDSNALEKVAGEIEKATGGKHRPLK 97

Query: 183 ITADLTKESDIE-KIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQ-YDRLMNTNVR 353
           I   L ++  +  ++I +T++ +G+LD LVNNAG     G + + +L   YD++ + NVR
Sbjct: 98  IIGGLVEDRQLPVRLINETVNEFGRLDFLVNNAGGSTAHGKLTDENLMDSYDKVFDLNVR 157

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533
           S+ +L  +A PHL ++KG          I   P  L Y+ SKA++D  T+C+A+E    G
Sbjct: 158 SVLHLCQVAKPHLEKTKGNIINISSIAAI--VPYSLIYSPSKAALDMMTKCLAIEYGDIG 215

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           VRVN +NPG + T   R  G+  + Y    +R      L      DE+A   +FLASD A
Sbjct: 216 VRVNSINPGPVRTGFLRSMGMQMDNYDELYDRYSSNTLLNFVPYGDEIANLASFLASDDA 275

Query: 714 SNITG 728
            N+TG
Sbjct: 276 KNLTG 280


>UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Rep:
           Blr1409 protein - Bradyrhizobium japonicum
          Length = 266

 Score =  126 bits (305), Expect = 4e-28
 Identities = 77/241 (31%), Positives = 130/241 (53%), Gaps = 3/241 (1%)
 Frame = +3

Query: 15  NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 191
           +  GKV                 L++LGA++ ++ R  +  ++V+   +      + I  
Sbjct: 16  DLTGKVAIVTGSSRGIGRSSAELLARLGAKVVVSSRKADACKEVADGINAAGGDAIVIPC 75

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 368
           ++ +++++E +I     HYGK+D+LV NA +    G + + +   +D++M +NV+S  +L
Sbjct: 76  NIARKAEVEALIAGATTHYGKIDILVCNAAVNPYYGPLLDITDEAFDKIMGSNVKSNIWL 135

Query: 369 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           + LA+P + E   G         G+R    + AY ISKA+     R +A E  PKGVRVN
Sbjct: 136 SALAIPQMAERGNGSVIIISSIGGLRGSTVIGAYGISKAADFALCRSLAGEWGPKGVRVN 195

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
           C+ PG++ T+  R   L E++  A L+R   T  L R G+PDE+A  +A+LASD +S +T
Sbjct: 196 CIAPGLVKTDFAR--ALWEDE--ALLKRRTATTPLRRIGEPDEIAGAVAYLASDASSFMT 251

Query: 726 G 728
           G
Sbjct: 252 G 252


>UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep:
           AGR_C_2317p - Agrobacterium tumefaciens (strain C58 /
           ATCC 33970)
          Length = 292

 Score =  126 bits (304), Expect = 6e-28
 Identities = 77/217 (35%), Positives = 111/217 (51%), Gaps = 1/217 (0%)
 Frame = +3

Query: 81  FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           FL    + + +TGRN  NL        K A  +   +D+ K SD+E++  +      K+D
Sbjct: 67  FLEGGASTVYVTGRNSANLDAAVAKLGKGA--IGFVSDVAKLSDLEQLKSRLEADGRKVD 124

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           VLV NAGI E   +  T  A YDR+ + NV+ ++Y     +P +L   G         G 
Sbjct: 125 VLVANAGIAENNDLGETHEALYDRIFDINVKGVFYTVQTLLP-VLRDGGSIVLTGSIVGN 183

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GLSEEQYAA 617
           +    + AYN SKA+V  F R  A +L  +G+RVN V+PGV  T +   G  + +E+ A 
Sbjct: 184 KGMERLSAYNASKAAVRSFARSFANDLKGRGIRVNTVSPGVTRTPIMENGLKMDDEKIAG 243

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           F    K+   +GR   PDE+A  + FLAS  AS ITG
Sbjct: 244 FKAYLKDAAPIGRMADPDEIAEAVLFLASSKASYITG 280


>UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Geobacter metallireducens (strain GS-15 / ATCC
           53774 / DSM 7210)
          Length = 255

 Score =  126 bits (303), Expect = 7e-28
 Identities = 72/217 (33%), Positives = 118/217 (54%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA L L  RN  ++ KV+ +   K    L++  D+ K  DI+ ++ K I  +G +D
Sbjct: 30  LAEAGANLVLASRNEASMAKVASEVTSKGVQCLTVKTDMLKADDIQAMVDKGIAQFGTID 89

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437
           +LVNNAGI       N +   +D +++TN++  +  + +    ++++K G         G
Sbjct: 90  ILVNNAGINLVKPFVNLTEEDWDSVVDTNLKGYFLCSQVVGREMIKNKNGCVINNASVFG 149

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           +R FP + +Y  SK  V Q TR +A+E A   +RVNC+ PG I+TE+ +R     E    
Sbjct: 150 LRGFPNIASYIASKGGVVQLTRGLAVEWARHNIRVNCIAPGYIVTEMAKR---DIETNPK 206

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            LE+      + R G+P EVA  + FLAS+ +S +TG
Sbjct: 207 ILEQNLLKIPMKRGGQPREVADVVVFLASEASSYMTG 243


>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Chloroflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
           9485
          Length = 256

 Score =  124 bits (300), Expect = 2e-27
 Identities = 82/247 (33%), Positives = 122/247 (49%), Gaps = 8/247 (3%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 188
           M F GKV                 L++ GA + +  R+      + +  + +    L++ 
Sbjct: 1   MEFQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVI 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           AD++ ESD  +I   T+  +G +D+LVNNAGI + GTIE+T+L  +  ++N N+  ++ +
Sbjct: 61  ADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVFLV 120

Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           +   +P L     G         G+R+  G  AY  SK  V   TR +AL+ AP G+RVN
Sbjct: 121 SRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDGAPDGIRVN 180

Query: 546 CVNPGVILTELQRRGGL------SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           CV PG+I T L R           +E+  AF  R      LGR G P+EVAA I  L S 
Sbjct: 181 CVCPGLIDTSLLRANAALVNTQRPDEELRAFARRV----PLGRLGTPEEVAAVILCLLSP 236

Query: 708 LASNITG 728
            A  +TG
Sbjct: 237 TAGYLTG 243


>UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 281

 Score =  123 bits (296), Expect = 5e-27
 Identities = 69/211 (32%), Positives = 116/211 (54%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ +TGRN E L   +K+    A  L++ AD T  +  E  I++  + +GK D++  N
Sbjct: 53  GAKVVITGRNKETLAAAAKELGPNA--LAVVADATDIAATEAAIRQGAEKFGKFDIVFAN 110

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AGI  +  +   +L  ++++++TN+  +++    A+PHL ++            +   PG
Sbjct: 111 AGIPGSTPLGAATLEVFEKVISTNLTGVFFTVQSALPHLNDNASIILNGSVI-SVLGIPG 169

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
             AY  +KA V    R +A EL+P+G+RVN V PG I T +      + E   AF +R  
Sbjct: 170 YSAYGAAKAGVRAMARIMASELSPRGIRVNVVAPGAIRTPIWGAAIATPEAEKAFEKRIA 229

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +  LGR G+PD ++ T+ FLASD +++I G
Sbjct: 230 LSTPLGRIGEPDHISKTVLFLASDDSAHIQG 260


>UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep:
           Bll5898 protein - Bradyrhizobium japonicum
          Length = 256

 Score =  123 bits (296), Expect = 5e-27
 Identities = 74/211 (35%), Positives = 108/211 (51%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA + L GR    L +V  +       +   AD+T  +D+E ++   +  +G++D+LVNN
Sbjct: 31  GAIVVLNGRRESKLAEVGAELGTDRCMIR-PADVTIAADVESLVADAVRRFGRIDILVNN 89

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG         + + Q+  L   NV  + Y+T  A+PHL+ES G         G+    G
Sbjct: 90  AGTGALIDFLGSPIQQWRDLFAVNVDGVLYMTRAALPHLIESGGSIVNVSSLSGLGGDRG 149

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
           +  YN +K +V   TR +ALE  P+GVR+N V P + LT L        EQY   L +  
Sbjct: 150 LSFYNATKGAVSNLTRSLALEFGPRGVRINAVCPSLTLTHLTMP---ILEQYPELLAKLV 206

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
               LGR  + +EVA+ IAFLASD AS + G
Sbjct: 207 GRIPLGRAAQSEEVASVIAFLASDDASFVNG 237


>UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=56; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 252

 Score =  122 bits (295), Expect = 7e-27
 Identities = 76/211 (36%), Positives = 113/211 (53%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA + LTGR    L   + +     S ++I  D +  SD+EKI+ +  +  GKLD+L  N
Sbjct: 33  GAFVFLTGRREPELLAAANELGP--SAIAIRTDSSLISDVEKILARIRETKGKLDILFAN 90

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AGI E   +   +   +D++ +TNV+ I +L   A+P L+ S            I+  P 
Sbjct: 91  AGIGEFLPLGVITEEHFDKIFSTNVKGIVFLVQKALP-LMPSGSSIVLNASIASIKGMPA 149

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
              Y+ SKA++  F R    +L  + +RVN V+PGVI T      GLS+++   FL+   
Sbjct: 150 FSIYSASKAALRSFARSWTTDLRRQQIRVNAVSPGVISTPGYDGLGLSKQEMETFLKTNA 209

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
           ET  LGR G PDEVA  + FL+SD +S I+G
Sbjct: 210 ETIPLGRVGTPDEVAKAVVFLSSDESSYISG 240


>UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia
           succiniciproducens MBEL55E|Rep: FabG protein -
           Mannheimia succiniciproducens (strain MBEL55E)
          Length = 248

 Score =  122 bits (294), Expect = 9e-27
 Identities = 73/215 (33%), Positives = 115/215 (53%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L++ GA++ + GR  + LQ+ +      A  +   AD+ K+ D++KI+++    YG LD+
Sbjct: 26  LAQEGAKVLVVGRTEKTLQETTALHPNIAYAV---ADIEKDDDVQKIVQQLNQKYGGLDI 82

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
           L+NNAG      I    + +YD++   NVR++  LT+  +P L   KG            
Sbjct: 83  LINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLTLQCLPMLKARKGNIINMSSAICRN 142

Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623
             P +  Y  +KA+V+ FT+  A EL   GVRVN ++ G I T +  +  LS +     +
Sbjct: 143 HLPNMSMYAGTKAAVEIFTKIWAKELGADGVRVNSISVGPIETPIYDKTDLSNDGIQDHI 202

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           +R ++T  LG  GK ++VA   AFLASD A  ITG
Sbjct: 203 DRIRKTIPLGAFGKSEDVANVTAFLASDEARFITG 237


>UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=4;
           Bacteria|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Psychroflexus
           torquis ATCC 700755
          Length = 269

 Score =  122 bits (293), Expect = 1e-26
 Identities = 69/211 (32%), Positives = 109/211 (51%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA + +TGR+ E + K S++         I AD+   S I+ ++ +    +GK+DVL  N
Sbjct: 48  GATVVITGRDSEKVAKASQEL----GVKGIVADVKSLSAIDDLVAQVKSDFGKVDVLFVN 103

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AGI +   +   S   +D  M+ N +  ++ T   +P +L                  P 
Sbjct: 104 AGIFQPAPVGQISEEMFDHQMSINFKGAFFTTEKFLP-ILNDGASVINLSSVNAYTGMPN 162

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
              Y  SKA+++ +TR  A ELAP+ +R+N VNPG + T +  + G+ EEQ   F E  +
Sbjct: 163 TAVYAASKAALNAYTRTAATELAPRKIRINSVNPGPVSTPIYGKTGMEEEQLNGFAEAMQ 222

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
               L R G+P+++A  ++FLASD AS ITG
Sbjct: 223 NRIPLKRFGQPEDIAKLVSFLASDDASFITG 253


>UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
           3-oxoacyl-[acyl-carrier protein] reductase -
           Arthrobacter aurescens (strain TC1)
          Length = 261

 Score =  121 bits (292), Expect = 2e-26
 Identities = 73/185 (39%), Positives = 101/185 (54%)
 Frame = +3

Query: 174 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 353
           TL + AD+     IE II ++++  G LDVLVNNAGI  TG    TS   +  +M  NV 
Sbjct: 60  TLKV-ADVGDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVD 118

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533
            ++Y T  A+PHL++S+G         GI +     AY+ SK +V  FTR VA++ A +G
Sbjct: 119 GLFYATRAALPHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVAVDYAQRG 178

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           VR N V PG +LT L ++   + +  A   E    +  LGR   P+E+A    FLAS  A
Sbjct: 179 VRCNAVAPGPVLTPLLQK---NLDSTAGLKEAFGRSIPLGRIAAPEEIAPAFTFLASSDA 235

Query: 714 SNITG 728
           S I G
Sbjct: 236 SYING 240


>UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 284

 Score =  121 bits (292), Expect = 2e-26
 Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 13/225 (5%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC----DKFASTLSITADLTKESDIEKIIKKTIDHYG 251
           L+  GA++++TGRN E L++             + L +  D+T+ES  E +IK T+D +G
Sbjct: 26  LASEGAKVTVTGRNAERLEETKNILLGAGVPEGNVLVVVGDITQESVQENLIKSTLDKFG 85

Query: 252 KLDVLVNNAGI----IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXX 419
           K+D+LVNNAG      +  +  N S+  Y +    NV+S+  +T  A PHL +++G    
Sbjct: 86  KIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQSVIEMTQKARPHLAKTQGEIVN 145

Query: 420 XXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR-RGG 593
                 G  +      Y+I+KA++DQ+TR  A++L P+G+RVN V+PG + T       G
Sbjct: 146 ISSIGAGPAAQVASPYYSIAKAALDQYTRTAAIDLVPEGIRVNSVSPGAVSTGFSAVSRG 205

Query: 594 LSEEQYAAF---LERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           L+EE+  AF   L   +E    G    P+++A  IAFLA   ASN
Sbjct: 206 LTEEKSKAFYDYLGAQRECIPRGFCAVPEDIAKVIAFLADRNASN 250


>UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanoculleus marisnigri
           (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 249

 Score =  120 bits (290), Expect = 3e-26
 Identities = 75/215 (34%), Positives = 113/215 (52%), Gaps = 4/215 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           G ++ ++GRN  E  + V++  +     + I AD+T E D+  ++ KT++ +G+LDV V 
Sbjct: 30  GGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRADVTVEDDVRNLVAKTVEAFGRLDVFVA 89

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF- 449
           N+G+   G        ++DR+++ N++ I+     AV  +L+ +G          I SF 
Sbjct: 90  NSGVGSLGDPHEVETEEWDRVLDVNLKGIFLCDKYAVQQMLK-QGQGGAIVNTGSIHSFV 148

Query: 450 --PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623
              GV AY  +K  V   TR +    A +G+R N V PG I T L     L  E Y    
Sbjct: 149 AKQGVTAYGAAKGGVAMLTRTLGTSYAAQGIRANFVAPGYIDTPL--LAALPREAY---- 202

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           E  K+ H +GR G+P EVA  + FLASD ASNITG
Sbjct: 203 EELKKLHPIGRLGRPMEVAKAVTFLASDDASNITG 237


>UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Short-chain dehydrogenase/reductase SDR - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 253

 Score =  120 bits (289), Expect = 4e-26
 Identities = 72/215 (33%), Positives = 116/215 (53%), Gaps = 4/215 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ L  RN+E L+   K+     ST ++T DL  ES   +++ + +D YGK+D+LVNN
Sbjct: 29  GAKVILIARNLEGLENTRKEIGNEDSTAAMTCDLVDESQTLQVVNQIMDTYGKIDILVNN 88

Query: 276 AGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 449
           AG I           ++  +L+N N+  ++ +T   +  + + K G           R+ 
Sbjct: 89  AGAINDPIHFHEMQNSEIQKLINVNLLGVFNMTKAVLTKMADVKSGSIVNIGSISSERAI 148

Query: 450 PGV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623
           P V    Y+ +KA++  FT+ +A+E A + +R NCVNPG+I      +  L + Q    L
Sbjct: 149 PRVHLAVYSATKAAIPMFTKSIAVEYARRNIRCNCVNPGII-NSGSIKPYLDDPQARKVL 207

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           E   E   L R G+P++VA  +A+LASD AS +TG
Sbjct: 208 E---ERLPLARVGEPEDVANAVAYLASDEASWVTG 239


>UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase
           precursor; n=3; Cyanobacteria|Rep: NAD-dependent
           epimerase/dehydratase precursor - Anabaena variabilis
           (strain ATCC 29413 / PCC 7937)
          Length = 251

 Score =  120 bits (288), Expect = 5e-26
 Identities = 68/217 (31%), Positives = 118/217 (54%), Gaps = 3/217 (1%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           +K  A++ + GR + E  + V    +       + +D+TKE+D++ ++ K +  +G+LD+
Sbjct: 26  AKQQAKVVVVGRRIDEGEETVRLIQEAGGEAFFVQSDVTKEADVKAMVDKAVGVFGRLDI 85

Query: 264 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 437
             NNAG++ E  ++   + A+YDR+MN NV+ ++      +  +L +  G         G
Sbjct: 86  AFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLSMKYEIAQMLKQGSGAIVNTSSGAG 145

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           + + PGV  Y  SK +V   T+  AL+ A  G+R+N V PG I T++       +++  A
Sbjct: 146 VVALPGVPLYTASKHAVVGLTKAAALQYAKAGIRINAVAPGSIETDMFEAATGGQDEVKA 205

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           ++      H +GR G P EVA  + FL+SD+AS ITG
Sbjct: 206 YI---TGLHPIGRIGTPLEVANAVLFLSSDIASFITG 239


>UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn)
           reductase precursor; n=1; Rhodopseudomonas
           palustris|Rep: Putative 3-oxoacyl-(Acyl carrier ptn)
           reductase precursor - Rhodopseudomonas palustris
          Length = 262

 Score =  119 bits (286), Expect = 8e-26
 Identities = 79/240 (32%), Positives = 118/240 (49%), Gaps = 1/240 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 188
           M F GKV                 L++ GA + L+  + + L + ++     A  +S + 
Sbjct: 1   MRFNGKVAVVTAAASGIGAATAARLAREGAYVYLSDIDQDALGRQAESLVDVAERISTVV 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           AD+T    +  +I       G+LD+L+NNAG+   G I   +   + R+    V SI++ 
Sbjct: 61  ADVTVPEQVSALIDGAARERGRLDILINNAGMGAFGRITEVTPEAWHRVFGICVDSIFHA 120

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
           +  A+PHL++++G         G+    G  AYN +K +V   TR +AL+ +  G+RVN 
Sbjct: 121 SRAAIPHLIKARGTIVNTASISGLFGDYGFAAYNAAKGAVINLTRNMALDYSRDGLRVNA 180

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           V PG+I T L     L     AA +        LGR G P+EVA  IAFLASD AS ITG
Sbjct: 181 VCPGLIATPL----SLKLRDNAAVMAEYDRLIPLGRAGSPEEVAGAIAFLASDDASYITG 236


>UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3;
           Proteobacteria|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Erythrobacter
           sp. NAP1
          Length = 267

 Score =  118 bits (285), Expect = 1e-25
 Identities = 76/241 (31%), Positives = 120/241 (49%), Gaps = 4/241 (1%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 197
           FAGK V                    GA + +  RN E   KV+   D    TL+   D+
Sbjct: 7   FAGKTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADTLDA-DRTLTCPGDV 65

Query: 198 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 377
           +      +I+ KT++ +G LD LVNNAG+  +  +  T   + DR+++ NV+ + YL   
Sbjct: 66  SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSMLHKTDDEEIDRIIDINVKGVIYLCRA 125

Query: 378 AVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           A+PHL +S+    G         GI     +  YN SK ++   TR +A ++   G+RVN
Sbjct: 126 AIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMGIRVN 185

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            +NP +  +++   G L+ +   A LE       +GR G+P+++AA  AFLAS+ A+ IT
Sbjct: 186 AINPSITRSDMV-DGILAND---ALLEAFMRRVPMGRIGEPEDIAAACAFLASEDAAFIT 241

Query: 726 G 728
           G
Sbjct: 242 G 242


>UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1;
           Zymomonas mobilis|Rep: Putative uncharacterized protein
           - Zymomonas mobilis
          Length = 254

 Score =  117 bits (282), Expect = 3e-25
 Identities = 74/247 (29%), Positives = 129/247 (52%), Gaps = 6/247 (2%)
 Frame = +3

Query: 6   VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLS 182
           V+ +++GKV                  +K  A +++ GR+  N+Q+  +   +     ++
Sbjct: 3   VSFDYSGKVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIA 62

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSL--AQYDRLMNTNVRS 356
           I AD+++E  I+  I+KT++ +GKLD   NNAG IE   I    +   ++DR+++TN+  
Sbjct: 63  IQADVSQEDSIKAAIEKTVETFGKLDFAFNNAG-IEHKAIPAADIPSEEWDRIISTNLNG 121

Query: 357 IYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533
           +++     +P +L+S  G         G++ FPG  AY  SK  +   ++  AL+ A + 
Sbjct: 122 VFFSMKHEIPAMLKSGSGSIVNTASGAGVKGFPGNGAYCASKFGLIGLSKAAALDYAKQH 181

Query: 534 VRVNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           +R+N V PG+I T + +R  GG  E +  A  +       +GR G P E+A T+ +L SD
Sbjct: 182 LRINVVAPGIIETPMMQRFTGGTEEGRETAIAQ-----EPVGRAGHPKEIAGTVLWLCSD 236

Query: 708 LASNITG 728
           LA+  TG
Sbjct: 237 LAAFTTG 243


>UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Rhodobacteraceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Rhodobacter sphaeroides
           (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158)
          Length = 259

 Score =  117 bits (281), Expect = 3e-25
 Identities = 64/183 (34%), Positives = 98/183 (53%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
           +I AD        + + + +D  G+LDVLVNNAG+++   +E  +LA ++R +  N+ + 
Sbjct: 46  AIAADFADADAPARAVAEAVDRAGRLDVLVNNAGVMQEARVEEMALADWERTIRVNLTAP 105

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
           +     A+PHL   +G         G+ + P   AY  SKA +   TR VA++   +G+R
Sbjct: 106 FLAIRAALPHLRAVRGAIVNVGSIEGLGANPRHAAYCASKAGLHGLTRAVAVDHGAEGIR 165

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
            N V PG I TEL      +     AF       H +GR G+P+EVAA +A+LASD A+ 
Sbjct: 166 CNAVAPGWIETELNEAFVEAMPDPEAFRRGIGRIHPVGRTGQPEEVAALVAWLASDEAAF 225

Query: 720 ITG 728
           +TG
Sbjct: 226 VTG 228


>UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Jannaschia sp. CCS1|Rep: Short-chain
           dehydrogenase/reductase SDR - Jannaschia sp. (strain
           CCS1)
          Length = 254

 Score =  116 bits (280), Expect = 4e-25
 Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 3/204 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA++++TGR  E L+ V+        + +I A D++ E D  ++I   + H G L  L N
Sbjct: 30  GAKVTITGRRAEKLEDVA---GAIGPSCAIAAGDVSIEEDRRRMIDTAVAHGGGLQGLFN 86

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452
           NAG +  G I + +      +MN NV +   LT LA PHL E  G           R+FP
Sbjct: 87  NAGNMLRGPITDLAAEDILEVMNVNVVAGMRLTGLAAPHLEEHGGAVVFVGSGHTRRAFP 146

Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL--SEEQYAAFLE 626
           G   Y  SK +V+   + +A EL PKG+RVNC+ PG + TE+  R G+  S E     L 
Sbjct: 147 GASPYAASKGAVEVLAQVLAAELGPKGIRVNCIVPGAVPTEINVRAGIAASFEDNKVRLN 206

Query: 627 RTKETHALGRPGKPDEVAATIAFL 698
              + H LGR G P E+A  +  L
Sbjct: 207 SMVDDHPLGRIGTPQEIAEAVDHL 230


>UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella sediminis HAW-EB3|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella sediminis
           HAW-EB3
          Length = 245

 Score =  116 bits (280), Expect = 4e-25
 Identities = 72/216 (33%), Positives = 112/216 (51%)
 Frame = +3

Query: 81  FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           F++K GA + +TGR    L++ S++         I  D++K+    +I+++TI  +G+LD
Sbjct: 26  FIAK-GATVVITGRRQSVLEETSQELGP--QVYPIVGDVSKKGGPARIVEETISKFGRLD 82

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           VLVNNAG  + G +  TS    + +  TNV ++  L   A  HL  SKG           
Sbjct: 83  VLVNNAGTGKMGPLSETSDEDIESIYRTNVFALLALVREATVHLANSKGAVVNISSVAAQ 142

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
              P V AY  SKA+V+  TR +A EL P G+RVN V PG+  T++      +EE     
Sbjct: 143 GMMPAVAAYASSKAAVEHATRLLAAELGPMGIRVNAVAPGLTNTDIAADVKSNEEMLGMI 202

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           + +T     +GR G+P ++A  +  ++   A  ITG
Sbjct: 203 IAQT----PMGRLGEPKDIANVVLLMSGSGAGWITG 234


>UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;
           n=4; Caenorhabditis|Rep: Dehydrogenases, short chain
           protein 15 - Caenorhabditis elegans
          Length = 278

 Score =  116 bits (280), Expect = 4e-25
 Identities = 73/223 (32%), Positives = 119/223 (53%), Gaps = 12/223 (5%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS----ITADLTKESDIEKIIKKTIDHYG 251
           L++ GA++++TGR+ E +Q+   +  K   +      +  DL +    +++IK T+  +G
Sbjct: 26  LAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIVLGDLNESECQDELIKSTLSRFG 85

Query: 252 KLDVLVNNAGII---ETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXX 419
           K+D+L+NNAG      +G I    ++  +D +M  N+RS+  L     PHL+ SKG    
Sbjct: 86  KIDILINNAGAAFADPSGKIGSEAAIGIFDDMMKLNLRSVVELVKKCRPHLIASKGEIVN 145

Query: 420 XXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
                 G + +     Y I KA +DQ TR +ALEL P  VRVN V+PG+I T      G+
Sbjct: 146 VSSIAAGPQPYIYYTYYGICKAGLDQLTRSLALELIPFDVRVNSVSPGLISTNFLGAVGM 205

Query: 597 SEE---QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
            ++   +   +    ++    GR GKP+E+A+ IAFLA   +S
Sbjct: 206 GDDVVKKTEEYYSTHRDCIPAGRTGKPEEIASLIAFLADRKSS 248


>UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;
           Thermobifida fusca YX|Rep: Short-chain alcohol
           dehydrogenase - Thermobifida fusca (strain YX)
          Length = 267

 Score =  116 bits (279), Expect = 6e-25
 Identities = 65/217 (29%), Positives = 113/217 (52%), Gaps = 6/217 (2%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA +    RN +     + D      T L++TAD++  +D E++   T++H+G++D++  
Sbjct: 33  GASVVCVDRNADAAHSAADDIAAAGGTALALTADVSSAADAERMTTTTLEHFGRIDIVFA 92

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 449
           NAGI  +G    T+  ++DR++  N++ ++  +  A+PH++E + G         G+   
Sbjct: 93  NAGIPGSGDAHTTTEEEWDRVIAINLKGVWLTSKYALPHMVERRSGVITNQASVGGLIGI 152

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL----QRRGGLSEEQYAA 617
           PG+  Y  +K  V   TR +A   AP  +RVN + PG + T L    +++ GL+      
Sbjct: 153 PGIFPYAAAKGGVISMTRQMAAAYAPHNIRVNAICPGGVYTPLVELSRQKRGLTASSVEE 212

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                   + LGR G  +E+A+   FLASD A+ ITG
Sbjct: 213 ANAIAARNYPLGRLGTVEEIASLALFLASDEAAWITG 249


>UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2;
           Frankia|Rep: Putative dehydrogenase/reductase - Frankia
           alni (strain ACN14a)
          Length = 295

 Score =  116 bits (279), Expect = 6e-25
 Identities = 70/213 (32%), Positives = 109/213 (51%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++++ GR+   +  V +        + I AD+T  ++  +I+  T+DH+G LD+L   
Sbjct: 75  GARVAVVGRDKAKMDAVVESLAPLGEIIGIQADVTVVAEAARIVSATVDHFGGLDILATV 134

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSF 449
           AG+ E   + + + A YD   + NV+  Y+    A  HL++   +G         G+R+F
Sbjct: 135 AGVFEGAPLLDATEADYDIQFDLNVKGTYFCAQAAARHLVDQGRRGKIITVGSVAGLRAF 194

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
           PGV  Y  +KA+V   T+ +A ELAP G+ VNCV PG I  ++     LS    A   E 
Sbjct: 195 PGVSVYGATKAAVGFLTQVLAGELAPHGINVNCVVPGSI--DMPTNKLLSPPGAA---EA 249

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           +       R G P +VAA   +LASD A  + G
Sbjct: 250 SAAGTPARRNGLPVDVAAAAVYLASDSADFVHG 282


>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 271

 Score =  115 bits (277), Expect = 1e-24
 Identities = 60/179 (33%), Positives = 94/179 (52%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D++K  D+E+ +   I  + ++D+LV+NAGI   G +  T    +DR++  N++  + ++
Sbjct: 64  DVSKSKDVEQAVGDVITKHSQIDILVSNAGIQYYGDVITTPEDDWDRVIGVNLKGCFLIS 123

Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551
              VPH++ + G            +     AY  SK +V    R +AL+ A KG+RVNCV
Sbjct: 124 KFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMALDYAHKGIRVNCV 183

Query: 552 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            PG I T +            + +      HALGR GKPDEVA  + +LAS ++S ITG
Sbjct: 184 CPGTIDTPMLHWAASLSPDPESVIRTCDRMHALGRIGKPDEVADAVLYLASPMSSFITG 242


>UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium sp. (strain KMS)
          Length = 251

 Score =  115 bits (277), Expect = 1e-24
 Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           GA ++ T G +V +  KV  D  +     L I AD +    I   + +T+   G LD+LV
Sbjct: 35  GAAVAFTYGSSVSDADKVVVDVSRGGGRVLPIRADSSDAGQIASAVDETVTRLGGLDILV 94

Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449
           NNAG+   G +E+  L Q+DRL+  NVR ++     AVPHL +                 
Sbjct: 95  NNAGVAHLGAVESFPLDQFDRLVAVNVRGVFVAIQCAVPHLGDGGRIINIGSVNADRVPS 154

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
           PG+  Y ++KA+V   TR +A EL P+G+ VN V PG I T++    G        F + 
Sbjct: 155 PGLSVYAMTKAAVAGLTRGLARELGPRGITVNTVAPGPIATDMNPAEG-------EFADA 207

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +E  A+G  G P +VA   ++LA   A  +TG
Sbjct: 208 AREIIAVGHYGNPTDVAGVASYLAGPDAGYVTG 240


>UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 402

 Score =  115 bits (276), Expect = 1e-24
 Identities = 80/250 (32%), Positives = 120/250 (48%), Gaps = 13/250 (5%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL----QKVSKDCDKFASTLSI 185
           F+GKV                  ++ GA++++TGRN E L    Q + K      + L+I
Sbjct: 126 FSGKVALVTGSSNGIGRAAALLFAQQGAKVTITGRNAERLEETRQAILKSGVPAENVLAI 185

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ----YDRLMNTNVR 353
            ADL  +     +I  T+  +G+LD+LVNNAG           + Q    +D+    N+R
Sbjct: 186 AADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVNDPQGRMGIDQQIEDFDKTFQINMR 245

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPK 530
           S+  L   A  HL+++KG         G   + P ++ Y +SKA++DQFTR  A+ L   
Sbjct: 246 SVVTLVQKAKEHLIKTKGEIINVSSIGGGPHAQPDMMYYGMSKAALDQFTRSTAITLIQH 305

Query: 531 GVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701
           GVRVN V+PG + T      G    + E+   + E  KE    G   +P E+A  IAFLA
Sbjct: 306 GVRVNSVSPGGVYTGFGEAMGFPPGALEKIMKYFESHKECVPCGHMAQPIEIAQVIAFLA 365

Query: 702 S-DLASNITG 728
              ++S I G
Sbjct: 366 DRTMSSYIIG 375



 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 39/95 (41%), Positives = 54/95 (56%), Gaps = 4/95 (4%)
 Frame = +3

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL---SEEQYAAFLE 626
           ++ Y +SKA++DQFTR  A+ L   GVRVN V+PGV+ T +    G    + E+   F E
Sbjct: 1   MMYYGMSKAALDQFTRSTAITLIQHGVRVNSVSPGVVYTGIGEAMGFPPGAFEKTMKFYE 60

Query: 627 RTKETHALGRPGKPDEVAATIAFLAS-DLASNITG 728
             KE    G   +P E+A  IAFLA   ++S I G
Sbjct: 61  SHKECVPCGHMAQPVEIAQVIAFLADRTMSSYIIG 95


>UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
           dehydrogenase/reductase SDR - Caldivirga maquilingensis
           IC-167
          Length = 283

 Score =  114 bits (275), Expect = 2e-24
 Identities = 75/241 (31%), Positives = 122/241 (50%), Gaps = 6/241 (2%)
 Frame = +3

Query: 24  GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS---TLSITAD 194
           GKVV                  ++G+++ +  R+ + +Q V K  + + S    + +  D
Sbjct: 16  GKVVIVTGSTRGIGYEIVKLFKEMGSRVVVNARSADEVQTVVKKLNDYVSDGEAIGVAGD 75

Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 374
           ++K  D EKI+ +T+D YGK+DVLVNNAGI       N S+  ++R +  ++ S +Y++ 
Sbjct: 76  VSKYEDCEKIVNETVDKYGKIDVLVNNAGINMIRDSLNLSIDDWERTLRIDLFSAFYMSQ 135

Query: 375 LAVPHLL--ESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           L    ++  + KG         G I + P   AY  +KA +   TR +A+E AP G+RVN
Sbjct: 136 LVARTMVAKKVKGSIVNIASMVGPIVALPKRAAYAAAKAGLVGLTRVLAVEWAPLGIRVN 195

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            + PG I +  Q    ++  +Y    +  +    +GR G   EVA    FLAS+LAS +T
Sbjct: 196 AIAPGYIWSSAQ-EVNIARGEYTR--QDIEGRVPMGRYGDAREVAYVAVFLASELASYVT 252

Query: 726 G 728
           G
Sbjct: 253 G 253


>UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2;
           Bacteroidetes|Rep: Short chain dehydrogenase -
           Algoriphagus sp. PR1
          Length = 252

 Score =  114 bits (274), Expect = 2e-24
 Identities = 67/216 (31%), Positives = 117/216 (54%), Gaps = 2/216 (0%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           S+ GA L L+GRN EN  ++ +  ++     + +  D+      E ++K  I ++GKLD+
Sbjct: 26  SEEGAFLILSGRNQENGIELERSLNEAGGKAVFVKGDVGIIETNEALVKAAISNFGKLDI 85

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGI 440
           +V NAG +  G++   SLA++   MNTN  ++++L+  A+P +++S  G           
Sbjct: 86  VVTNAGKLGLGSVTEISLAEWQETMNTNFNAVFFLSRFAIPEMIKSGGGTILANSSIAAF 145

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
           +SFP   AY  SKA++    + +A++  P  +RVN + PG + T L      + +     
Sbjct: 146 KSFPNHAAYCASKAALVALVKEMAVDYGP-NIRVNTMCPGPVDTPLIWDSAKAFDNPDTI 204

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           ++ T +   + R GKP+++A+   FL SD AS ITG
Sbjct: 205 VQETAKNTLMNRLGKPEDIASLALFLVSDEASWITG 240


>UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase
           bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis
           oxidoreductase bacC - Bacillus subtilis
          Length = 253

 Score =  113 bits (273), Expect = 3e-24
 Identities = 65/187 (34%), Positives = 105/187 (56%), Gaps = 5/187 (2%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           +  D+T E+  +  ++  +  +G LDVL+NNAGI     I    L+ +++++  N+  ++
Sbjct: 57  VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 116

Query: 363 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
            ++  A+ H+L + KG         G+ ++P + AYN SK  V Q T+ +A++ A   +R
Sbjct: 117 LMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 176

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFLASD 707
           VNCV PG+I T L  +  L  E     LE  K+  A    L R GKP+E+A  + FLASD
Sbjct: 177 VNCVCPGIIDTPLNEKSFL--ENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASD 234

Query: 708 LASNITG 728
           L+S +TG
Sbjct: 235 LSSYMTG 241


>UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 258

 Score =  113 bits (272), Expect = 4e-24
 Identities = 66/216 (30%), Positives = 115/216 (53%), Gaps = 5/216 (2%)
 Frame = +3

Query: 96  GAQ-LSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           GA+ L + GR    ++  +  C +  A+ +++  D+T+E D+ +++   ++  G+LDV  
Sbjct: 37  GAEALIIAGRREAEIEATAAACREIGAAAIALKTDITREDDVARLVGIAVERCGRLDVAF 96

Query: 270 NNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIR 443
           NNAG  E    +E      YD + +TNVR+++      +P +L + +G         G+R
Sbjct: 97  NNAGFQERRAPLEEQGTEIYDSVFDTNVRALFLCLRHQLPAMLAQGRGSIVVNASVSGVR 156

Query: 444 S-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
           +  PG   Y+ SKA+    TR  A+E AP+G+R+N + PG ++T++  R G+ +    A 
Sbjct: 157 NPNPGFSLYSASKAAAISLTRSAAMENAPRGIRINAIAPGRVVTDMMLRAGVGDVATVA- 215

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                    L R G P+EVA  + +L+SD AS + G
Sbjct: 216 -----AGLPLRRMGSPEEVAEAVVWLSSDAASYVVG 246


>UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcohol
           dehydrogenase TsaC; n=5; Proteobacteria|Rep:
           Toluenesulfonate zinc-independent alcohol dehydrogenase
           TsaC - Comamonas testosteroni (Pseudomonas testosteroni)
          Length = 252

 Score =  113 bits (271), Expect = 6e-24
 Identities = 71/218 (32%), Positives = 113/218 (51%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           LS+ GA + +   N E  Q+++ + +      L +  D++KE+D   ++   I   G L 
Sbjct: 25  LSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSKEADYRAVVDAAIAQLGGLH 84

Query: 261 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 434
           ++VNNAG           +  ++DR+   N++S+Y+    A+PH  +   G         
Sbjct: 85  IVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCALPHFAQQGHGVMVNVASTT 144

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G+R  PG+  Y+ SKA++   T+ +ALE A  GVR+N VNP +  T +     +  E   
Sbjct: 145 GVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRINAVNPMIGETPMM-ADFMGMEDTP 203

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A  ER      LGR  +PD+VA+ +AFLASD AS +TG
Sbjct: 204 ANRERFLSRIPLGRFTRPDDVASAVAFLASDDASFLTG 241


>UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=1;
           Pseudoalteromonas haloplanktis TAC125|Rep:
           7-alpha-hydroxysteroid dehydrogenase - Pseudoalteromonas
           haloplanktis (strain TAC 125)
          Length = 264

 Score =  112 bits (270), Expect = 7e-24
 Identities = 71/221 (32%), Positives = 124/221 (56%), Gaps = 6/221 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L+  GA + +T R +E++++ +    +  S  L +  D+  E   + ++ KTI+H+G+LD
Sbjct: 31  LADAGADIVVTARTIEDIEQTAAQIRQRGSRALVVACDVLDEQQRQSLVDKTIEHFGRLD 90

Query: 261 VLVNNAGIIETGTIENT---SLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXX 425
           +LVNN G   +G I+ T   S A+ +     N  + + L+ ++ PH++ +  +G      
Sbjct: 91  ILVNNVG--GSGAIKPTLSSSAAELENCFKLNTATAFDLSRISAPHMVNTSGQGSIINIS 148

Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 605
              G  + PG ++Y I+KA+++  T  +A + APK VRVN ++ G  LTE   +G +++E
Sbjct: 149 SVAGQLAQPGFISYGIAKAALNFMTLNLAQDFAPK-VRVNAISVGSTLTE-ALKGVMNDE 206

Query: 606 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              A ++RT     + R G+P++VAA   FLAS  A  ITG
Sbjct: 207 MEQAIVKRT----PMNRLGQPEDVAACALFLASPAAGYITG 243


>UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductase;
           n=1; Microscilla marina ATCC 23134|Rep:
           3-oxoacyl-acyl-carrier-protein reductase - Microscilla
           marina ATCC 23134
          Length = 253

 Score =  112 bits (270), Expect = 7e-24
 Identities = 70/218 (32%), Positives = 113/218 (51%), Gaps = 2/218 (0%)
 Frame = +3

Query: 81  FLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGK 254
           FL++ GA++ +TGR+ E L+  +++  K  +   L+I AD    +  +K+ +   D +GK
Sbjct: 26  FLAE-GAKVVVTGRSDEKLKATNEELAKIHANHFLTIKADAADVTSNKKVFEAAQDKFGK 84

Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 434
           +D+L  NAG+     + + + A YD +MNTN++  ++L    +P+  E            
Sbjct: 85  VDILFANAGVGRFMPLSDVTEAMYDEVMNTNLKGPFFLVQAGLPYFNEGASIILNTSVSN 144

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
            +   PG  AY  SKA +    R  A EL+   +RVN ++PG I T +  + GL EE   
Sbjct: 145 QM-GMPGASAYAASKAGLRLLARVFAAELSAHKIRVNAISPGPIDTPIWGKTGLPEEAVQ 203

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                     ALGR G  +E+A ++ FLAS  AS +TG
Sbjct: 204 EMGAGIASQVALGRFGTSEEIAKSVLFLASQDASFVTG 241


>UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Geobacillus kaustophilus
          Length = 256

 Score =  112 bits (269), Expect = 1e-23
 Identities = 77/225 (34%), Positives = 114/225 (50%), Gaps = 10/225 (4%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS---TLSITADLTKESDIEKIIKKTIDHYGK 254
           L++ GA + L GR    L++  +D  +           AD+T    +  +     + YG 
Sbjct: 25  LAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADRFAADVTDHEQVRALAAYVQNRYGD 84

Query: 255 LDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 431
           L VLVNNAGI   T  +E T   ++D +   N++S++ ++    P ++E           
Sbjct: 85  LHVLVNNAGISTHTKWLELTE-QEWDDVQRVNMKSVFLVSQTLAPLMIEGAKRERANRAI 143

Query: 432 XGIRSFPGVLA------YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGG 593
             + S  G  A      Y+ +KA V   T+ +ALELAP G+RVN V+PG + T L  R G
Sbjct: 144 VNVASLSGHQAGAEIPHYSAAKAGVINLTKSLALELAPYGIRVNSVSPGFVETPLTER-G 202

Query: 594 LSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           L  E++   +ER     ALGR G P+E+A  IAFLAS  AS +TG
Sbjct: 203 LQNERFVKAIERNT---ALGRVGAPEEIANVIAFLASSEASYMTG 244


>UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 251

 Score =  112 bits (269), Expect = 1e-23
 Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 4/243 (1%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 188
           M   GKV                 L++ GA++ +   NVE  +K  +D  K     L + 
Sbjct: 1   MRLEGKVCVVTGGATGIGEASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVE 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYY 365
            D+++E    +++++T+  +G++DVL NNAGI I  G++    +  + R    NV  I++
Sbjct: 61  CDVSREEGARRLVEETVGAFGRIDVLFNNAGINITEGSVPEMKVEDWRRTFAVNVDGIFW 120

Query: 366 LTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
            +  A+P + ++ G              + G  AY  SK +V   TR +A++ A + +RV
Sbjct: 121 CSRYAIPEMRKNGGGRIINTASPSSFVGWAGNAAYIASKGAVMSLTRAMAMDHAKENIRV 180

Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKET-HALGRPGKPDEVAATIAFLASDLASN 719
           N + PG+IL+ L    GL+  Q     E  KE+ H +GRPG P++VA  + FLA D A  
Sbjct: 181 NAIVPGLILSPL----GLNWVQQQEDPEAVKESIHPIGRPGYPEDVAPVVVFLAQDDAEF 236

Query: 720 ITG 728
            TG
Sbjct: 237 ATG 239


>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Bacillus coagulans 36D1|Rep: Short-chain
           dehydrogenase/reductase SDR - Bacillus coagulans 36D1
          Length = 262

 Score =  112 bits (269), Expect = 1e-23
 Identities = 76/249 (30%), Positives = 124/249 (49%), Gaps = 9/249 (3%)
 Frame = +3

Query: 9   TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSI 185
           T +F GKV                 L+  GA + +   + E   +   K  +     + +
Sbjct: 3   TFDFTGKVAIVTGGGGGIGREACLKLAAGGANVVVADLSDELGEETAGKIRENGGEAIFV 62

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIY 362
             D++K  D++  ++  +D YGK+D+L+NNAG   +   + +     +D+LM  NVR ++
Sbjct: 63  RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122

Query: 363 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
                 +PH++  K G         G+   P ++AY  SK +V   T+   +E AP GVR
Sbjct: 123 LGMKYVLPHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAGIEAAPSGVR 182

Query: 540 VNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFLA 701
           VN V PGV+ TE+ R+   G +    AA  E+T++  A     GR  +P+EVA  + +LA
Sbjct: 183 VNAVCPGVVDTEMMRKIENGFAGGDSAA-AEQTRQQMAASAPTGRYTQPEEVANVLLYLA 241

Query: 702 SDLASNITG 728
           SDL+S+I G
Sbjct: 242 SDLSSHIIG 250


>UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=4;
           Bacteria|Rep: Predicted short chain dehydrogenase -
           Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
           (strain EbN1))
          Length = 250

 Score =  111 bits (268), Expect = 1e-23
 Identities = 63/211 (29%), Positives = 108/211 (51%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA+++  GRN E L  ++         +++  D T   D+++++ +T+  +G +D++V N
Sbjct: 31  GAKVAAFGRNTEALDALA--AAHAGKVVTVKGDATCAEDLQRLVDETLKAFGGVDIVVPN 88

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AGI    + E+++   ++   + N+ +      L +PH+               +  FPG
Sbjct: 89  AGIARVVSFEDSTREAFETQFSVNLFAAAETVRLFLPHIRRGGSVQFITTFLTQV-GFPG 147

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
           +  Y+ SKA++  F + +A ELAP+G+RVN + PG I T L    GL  +   A   +  
Sbjct: 148 LAIYSASKAALKSFAQTLAAELAPRGIRVNSIAPGPIATPLWGTVGLPPDVLGAVAGQIN 207

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
                G  GKP+++A T  FLASD A NI G
Sbjct: 208 SRLMTGEFGKPEDIAETSVFLASDGAKNIYG 238


>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 277

 Score =  111 bits (268), Expect = 1e-23
 Identities = 67/170 (39%), Positives = 95/170 (55%), Gaps = 1/170 (0%)
 Frame = +3

Query: 222 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LE 398
           +I  T+  +G+LD+LVNNAGI   G +   SL  +D L+  NV S++Y    A+PH+  +
Sbjct: 72  LIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRAAIPHMRRQ 131

Query: 399 SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
             G         G+R      AY+ SKA+V  FTR +AL+ A + +RVN + PG + TE+
Sbjct: 132 GGGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALDHADENIRVNAICPGSVETEM 191

Query: 579 QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                +S   Y A   +  +T    R G+PD+VAA  AFLASD AS I G
Sbjct: 192 NNL-MMSRPDYIA---QWIKTIPANRFGRPDDVAALAAFLASDDASFIVG 237


>UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase family
           oxidoreductase, putative; n=1; Neosartorya fischeri NRRL
           181|Rep: Short chain dehydrogenase/reductase family
           oxidoreductase, putative - Neosartorya fischeri (strain
           ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
           fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
          Length = 255

 Score =  111 bits (268), Expect = 1e-23
 Identities = 75/223 (33%), Positives = 113/223 (50%), Gaps = 8/223 (3%)
 Frame = +3

Query: 84  LSKLGAQ-LSLTGRNVENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKL 257
           L+KLGA  L+L+  NVE LQK   +C ++ S +++T  D+++   + +   +T+  +G+L
Sbjct: 27  LAKLGAAGLALSDVNVEGLQKTKDECSRYESNVTVTRVDVSRNDQVTRWASETVQQFGRL 86

Query: 258 DVLVNNAGIIE---TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXX 428
           D   N AGI     T   E  S   +DRLM+ N++ +       +PHL    G       
Sbjct: 87  DGAANIAGIAMGDGTTNCETISPESWDRLMDVNLKGVMLCMRAQLPHLPRPGGVIVNVSS 146

Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG---GLS 599
             G+R  P   AY+ SK  V   +   A E  P G+R+N + PG + T + R G   GL 
Sbjct: 147 TSGLRGLPHNAAYSSSKFGVIGLSASAAGEFGPLGIRINSLLPGPVDTAIFRDGEARGLF 206

Query: 600 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           + Q       +K T  LGR G+  E+A  + FL SD AS +TG
Sbjct: 207 DSQIL-----SKAT-CLGRMGQAHEIANVLCFLLSDDASYVTG 243


>UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 249

 Score =  111 bits (268), Expect = 1e-23
 Identities = 70/214 (32%), Positives = 112/214 (52%), Gaps = 3/214 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQK--VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           GA++ +T  + E   K  V++   K  S ++I AD+  E D++K+I K    YG+LD+LV
Sbjct: 31  GAKVVITWESHEESAKNVVNEIHHKNGSAMAIQADVRNEDDVKKVINKIKGEYGRLDILV 90

Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRS 446
           NNAGI++   +  T   ++D L+ TN +  +  +  A   +L+ K G         G+  
Sbjct: 91  NNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYSRAAAKLMLKHKSGRIINISSVVGVYG 150

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626
             G   Y+ +K+ +  FT+ +A EL P G+ VN + PG I T+L     + +E     L 
Sbjct: 151 SKGQSVYSATKSFLIAFTKSLAKELGPFGITVNAIAPGFIDTDLTH--DVKDETRQDLLS 208

Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                  LGR G+ D++A  + FLASDL S + G
Sbjct: 209 HI----PLGRIGQADDIAKAVVFLASDLGSYVNG 238


>UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=14; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 274

 Score =  111 bits (267), Expect = 2e-23
 Identities = 65/196 (33%), Positives = 104/196 (53%), Gaps = 12/196 (6%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           L +  D+  ++ ++ ++ +TI  +G++DVLVNNAGI         + A +D ++  N++ 
Sbjct: 65  LYVHCDVGDKAQVDALVAQTIAAHGRIDVLVNNAGIFRAADFLEITEADFDAVLRINLKG 124

Query: 357 IYYLTMLAVPHLLE-----------SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTR 503
            + +       +             S+G          + + P + +YN+SK  ++Q TR
Sbjct: 125 SFLVGQAVAREMARAEARPGIGGSASRGSIVNMSSVNSVLTIPTIASYNVSKGGINQLTR 184

Query: 504 CVALELAPKGVRVNCVNPGVILTELQRRGGL-SEEQYAAFLERTKETHALGRPGKPDEVA 680
            +AL LA KG+RVN V PG I T+L  +  L SEE  A  + RT     + R G+P E+A
Sbjct: 185 VMALALADKGIRVNAVAPGTIATDLAAKAVLTSEEAKARIMSRT----PMKRLGEPSEIA 240

Query: 681 ATIAFLASDLASNITG 728
            T+A+LASD AS ITG
Sbjct: 241 DTVAYLASDAASYITG 256


>UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain
           dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep:
           Putative oxidoreductase; short-chain
           dehydrogenase/reductase - Frankia alni (strain ACN14a)
          Length = 297

 Score =  111 bits (267), Expect = 2e-23
 Identities = 78/241 (32%), Positives = 119/241 (49%), Gaps = 4/241 (1%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITAD 194
           FAG VV                 +  GA + +  R     ++  ++  ++  S   +  D
Sbjct: 36  FAGTVVLVTGAGRGLGRTIAEAFAVEGATVVVAARTARYGERTVREFRERGLSASLVIGD 95

Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 374
           L + +D+  +  + +  +G LDV+V++A     G +        D L+ +NV +++++T 
Sbjct: 96  LAERADVATMFDEAVARHGALDVVVHSAADNAQGLLAEIDDDTLDYLLRSNVHALHWITR 155

Query: 375 LAVPHLLESK--GXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
            AVPHL  SK  G           R F PG+ AY  +KA ++ F R +A EL P GVRVN
Sbjct: 156 AAVPHLTRSKLPGRMIFISSGAANRVFSPGLNAYGSTKAYLESFARGLAGELGPLGVRVN 215

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            V PG+ +TE +  G L+  Q  A       T+ LGR G P+E+AA + FLAS  AS IT
Sbjct: 216 VVGPGLTVTE-RMLGHLTHAQADAL----ASTYPLGRAGLPEEIAAAVLFLASREASYIT 270

Query: 726 G 728
           G
Sbjct: 271 G 271


>UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Pedobacter sp. BAL39|Rep: Short-chain
           dehydrogenase/reductase SDR - Pedobacter sp. BAL39
          Length = 250

 Score =  111 bits (267), Expect = 2e-23
 Identities = 64/212 (30%), Positives = 112/212 (52%), Gaps = 1/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA  ++ GRN E L++ +    D F   ++I  D+T   D+E++++ T + +GK+D+LV 
Sbjct: 30  GASGAIVGRNQETLKRAASQLGDGF---IAINGDVTNPGDLERMMRNTSEQFGKIDILVA 86

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452
           NAG   TGT+ + S + YD+ M+ N++S+Y+    A+P++ +              R++P
Sbjct: 87  NAGAGTTGTVADISESDYDKTMDLNLKSVYFTVQKALPYMADGSS-IILIGSNAAHRAYP 145

Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632
               Y  +KA+V    +  + +L  + +RVN + PG   T    +  +  EQ  A     
Sbjct: 146 SFGLYGAAKAAVIFLAKSFSNDLLDRKIRVNVITPGTTDTPAFDK-FVPAEQIEALKTHF 204

Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728
             T  +GR G+P ++  T  FLASD +S + G
Sbjct: 205 AGTMPIGRIGQPSDIGKTAVFLASDDSSFLLG 236


>UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Congregibacter litoralis KT71|Rep: Short-chain
           dehydrogenase/reductase SDR - Congregibacter litoralis
           KT71
          Length = 253

 Score =  111 bits (266), Expect = 2e-23
 Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 1/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ +   N+E  +KV+++         +  ++T E+  +  ++ T+  +G+LD+ VNN
Sbjct: 31  GARVMIGDINLEQGRKVAEELSSLGDIAFVENNVTAEASCQNAVEHTVKRFGRLDIAVNN 90

Query: 276 AGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452
           AG+I ET  +   S   + R MN N+  +++     V  +L + G            + P
Sbjct: 91  AGVIGETKPLLELSAEGWQRTMNININGVFFGLKAQVNQMLATGGSIINLASIASKIATP 150

Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632
               Y  SK +VD  T+  AL+ A  G+R+N V PGVI T L    G +++   + ++  
Sbjct: 151 SCADYITSKHAVDGLTKAAALDYATMGIRINSVGPGVIETPLLGTIGQTKDAQGS-IKHA 209

Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728
              H +GR GK  EVA  I +LASD AS  TG
Sbjct: 210 IGMHPMGRVGKVGEVANLITWLASDQASFCTG 241


>UniRef50_Q1Q261 Cluster: Strongly similar to
           3-oxoacyl-[acyl-carrier protein] reductase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to 3-oxoacyl-[acyl-carrier protein] reductase -
           Candidatus Kuenenia stuttgartiensis
          Length = 239

 Score =  110 bits (265), Expect = 3e-23
 Identities = 68/203 (33%), Positives = 112/203 (55%), Gaps = 2/203 (0%)
 Frame = +3

Query: 126 VENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI 302
           +++++K+ ++      + SI  AD+T  + I++++   +  +GK+DVL+NNAGII+ G I
Sbjct: 33  IDDIEKLREEFSSPQGSFSIEKADVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYI 92

Query: 303 ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISK 479
              S   ++ ++N N+  ++  T     H++ +  G         GI   PG   Y+ +K
Sbjct: 93  MLMSAKDWNDVINVNLTGVFNCTKAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAK 152

Query: 480 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRP 659
             V  FT  ++ ELAP  +RVN V PGVI T++     L + +  ++    KE   L R 
Sbjct: 153 GGVIAFTMALSKELAPFCIRVNTVAPGVIETDI--IDSLDKNKRNSY----KEHIPLKRF 206

Query: 660 GKPDEVAATIAFLASDLASNITG 728
           GKP+EVA+ + FLAS  AS ITG
Sbjct: 207 GKPEEVASVVRFLASSEASYITG 229


>UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 259

 Score =  110 bits (265), Expect = 3e-23
 Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 1/183 (0%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           +  DL++  + E+++++  +  G LDVLVNNAGI       +T    YD + + N++  +
Sbjct: 59  VRGDLSRVPECERVVEEAAEALGGLDVLVNNAGITRALDFLDTDEETYDAIFDLNMKGYF 118

Query: 363 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
           +    AVPH+LE+  G         G   FP   AY  +K ++  FTR +A+ELA +G+R
Sbjct: 119 FCARSAVPHMLEAGGGSIVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIR 178

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN + PG+I  E+ R   +    Y+   E+ +E    GR GKP +V    AFLASD A  
Sbjct: 179 VNAIGPGLI--EVPRYYDI--PGYSP--EQGRELVPWGRVGKPKDVGPAAAFLASDAADF 232

Query: 720 ITG 728
           ITG
Sbjct: 233 ITG 235


>UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified
           Gammaproteobacteria (miscellaneous)|Rep: Oxidoreductase
           - gamma proteobacterium HTCC2207
          Length = 253

 Score =  110 bits (264), Expect = 4e-23
 Identities = 67/220 (30%), Positives = 111/220 (50%), Gaps = 4/220 (1%)
 Frame = +3

Query: 81  FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           F+S+ GA++ L   N +  Q +  +   +     +  D+ +   +E +++ T+D +G +D
Sbjct: 25  FVSE-GAKVMLADINTDITQPLVNELGAYRCAC-VAVDVAEADQVENMVRTTVDTFGSID 82

Query: 261 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX- 434
           V V NAG   + G+I +T ++  D+++  NVR ++      +P + +  G          
Sbjct: 83  VFVANAGTEGKIGSIMDTDVSNLDKVLAVNVRGVWLGLHYVMPVMRDGGGGSIIITSSGA 142

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQ 608
           G++  P   AYN SK +V    RC ALE A  G+RVN VNPG + T +      G +E  
Sbjct: 143 GVQGSPNTAAYNTSKHAVIGLMRCAALESAQFGIRVNTVNPGAVETRMMESIEDGFAEAG 202

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              F    +    LGR G+P+E+A  + FL SD +S  TG
Sbjct: 203 AGDFRAMVEAVTPLGRYGQPEEIANMMVFLGSDDSSYCTG 242


>UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=4; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 268

 Score =  110 bits (264), Expect = 4e-23
 Identities = 66/218 (30%), Positives = 111/218 (50%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L+ +GA +++   NVE  ++ + + D     ++   D+T E  +E +++   D  G +DV
Sbjct: 42  LTDMGADVAIADVNVEKAERTASELDGETDVIATEVDVTDEGSVEAMVEDVTDRLGPIDV 101

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGI 440
           LVNNAGI+E    E TS+  + R+++ N+  ++         +L   +G         G 
Sbjct: 102 LVNNAGIVENSPAEETSVESWRRVVSVNLDGVFLCAKHVGQQMLNRGEGRIVNISSMSGF 161

Query: 441 R-SFPGVLA-YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
             + P   A YN +KA V   T+ +A+E   +GVRVN + PG + TEL        E+  
Sbjct: 162 DVNVPQKQASYNTTKAGVRMLTQSLAVEWGDQGVRVNAIAPGYMRTELVDE---VLEENP 218

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              E   E   +GR G+P+E+   + +LASD +S +TG
Sbjct: 219 EMEETWLENTPMGRLGRPEELKELVVYLASDASSYMTG 256


>UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 269

 Score =  109 bits (263), Expect = 5e-23
 Identities = 67/194 (34%), Positives = 98/194 (50%), Gaps = 7/194 (3%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII------ETGTIENTSLAQYD 329
           A  +++  DL +E  +E ++++T+ H+G+LDVL NNA ++        G +E    A +D
Sbjct: 55  AGAIALPLDLEQEQSVETLVERTVAHFGRLDVLHNNAALLGPEIAQADGDVERMGTALWD 114

Query: 330 RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCV 509
           R    NVR        A+PHL E++G          ++      AY+ SKA+V Q TR +
Sbjct: 115 RTFAVNVRGTMIACRAALPHLRETRGCIVNTVSNLALQGHLIQAAYSSSKAAVIQMTRAI 174

Query: 510 ALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHAL-GRPGKPDEVAAT 686
           A      GVR N V PG+ +T   R      E +   L +  E   L  R G P ++A  
Sbjct: 175 AASHGKAGVRCNAVAPGMTMTPALR------EAFPPALRQVVEDETLRDRLGDPRDIAEA 228

Query: 687 IAFLASDLASNITG 728
           IAFLASD A N+TG
Sbjct: 229 IAFLASDAARNVTG 242


>UniRef50_P50162 Cluster: Tropinone reductase 1; n=77;
           Viridiplantae|Rep: Tropinone reductase 1 - Datura
           stramonium (Jimsonweed) (Common thornapple)
          Length = 273

 Score =  109 bits (263), Expect = 5e-23
 Identities = 75/223 (33%), Positives = 120/223 (53%), Gaps = 8/223 (3%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHY--GK 254
           L+ LGA++    RN + L +  +   +K  +      DL   ++ +K+++ T+ H   GK
Sbjct: 41  LAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTERDKLMQ-TVAHVFDGK 99

Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431
           L++LVNNAG++     ++ +   Y+ +M TN  + Y+L+ +A P L  S+ G        
Sbjct: 100 LNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSI 159

Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ----RRGGLS 599
            G  + P V  Y+ SK +++Q T+ +A E A   +RVN V PGVILT L     ++    
Sbjct: 160 AGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQ 219

Query: 600 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           +E+   F+ +T     +GR GKP EV+A IAFL    AS ITG
Sbjct: 220 KEEIDNFIVKT----PMGRAGKPQEVSALIAFLCFPAASYITG 258


>UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2;
           Streptomyces|Rep: Putative dehydrogenase - Streptomyces
           coelicolor
          Length = 255

 Score =  109 bits (262), Expect = 7e-23
 Identities = 71/245 (28%), Positives = 113/245 (46%), Gaps = 5/245 (2%)
 Frame = +3

Query: 9   TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSI 185
           T  F GK                  L+  GA + + GR    L + +   ++     L++
Sbjct: 3   TQRFTGKTALVTGAGSGIGRAVALALAAEGAHVVVAGRARGPLDETAALVEQAGGKALAV 62

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIY 362
           TAD+T+  D++ ++   ++H+G LDV VNNAG+   G  + + S   +   ++ NV  ++
Sbjct: 63  TADVTRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVF 122

Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGI---RSFPGVLAYNISKASVDQFTRCVALELAPKG 533
                 V H+    G              +  PG  AY  +KA+V   TR  AL+    G
Sbjct: 123 LALRAEVRHMRAQPGGGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAALDHIGDG 182

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           VR+N V+PG   T +  R G +E   A   ER ++   LGR     EVAA + +LASD A
Sbjct: 183 VRINAVSPGATATSMSLRPGETE---AGRAERMRQETPLGRVSAVAEVAAAVLYLASDDA 239

Query: 714 SNITG 728
           +++ G
Sbjct: 240 ASVVG 244


>UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia phymatum
           STM815
          Length = 257

 Score =  109 bits (262), Expect = 7e-23
 Identities = 72/238 (30%), Positives = 109/238 (45%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           M+FA K                  L   GA++++TGR+ + L + + +     S L I A
Sbjct: 1   MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGP--SALPIRA 58

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D+   + I+ ++K   D +GKLD++  NAG+     +  T+  +++ +M TNV S++   
Sbjct: 59  DINDPAAIDAVMKTIADTFGKLDIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTV 118

Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551
             AVP L+   G              PG  AY+ SKA++    R +A EL  +G+RVN V
Sbjct: 119 QAAVP-LMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMARVLASELVTRGIRVNTV 177

Query: 552 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            PG   T +  RG        A          + R    DEVA    FLASD AS +T
Sbjct: 178 IPGGTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMT 235


>UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|Rep:
           Putative - Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 253

 Score =  109 bits (261), Expect = 9e-23
 Identities = 71/241 (29%), Positives = 120/241 (49%)
 Frame = +3

Query: 6   VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI 185
           ++  F GKV                 L + GA + ++GR  + L  V+       S + +
Sbjct: 1   MSKRFDGKVAIVTGGGSGIGAAIANRLLEEGASVMMSGRTEKRLSDVASKMPADRSGIFV 60

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365
            A+++   D + ++  T++ +G++D +VN AG+   GTI+ TS   +D  + +++  ++Y
Sbjct: 61  -ANVSSRPDCDALVAATVERFGRIDTVVNAAGMNFVGTIQETSDQDWDECIASDLSGVFY 119

Query: 366 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           ++  AVPHL E+KG          +       AYN +K  V   TR  A +L   GVR N
Sbjct: 120 MSRAAVPHLKETKGSIVNIGSVSSLGGGWSHAAYNAAKGGVANLTRSAACDLGKFGVRAN 179

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            V PG+ +T +     + ++   A LE+  +   L R G+P   A+ +AFLASD A+ IT
Sbjct: 180 TVAPGLTVTGMVE--AIMDDD--ALLEKAWDRIPLRRAGQP---ASAVAFLASDEAAWIT 232

Query: 726 G 728
           G
Sbjct: 233 G 233


>UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
           reductase; n=2; Bacillaceae|Rep:
           3-ketoacyl-(Acyl-carrier-protein) reductase - Bacillus
           sp. B14905
          Length = 248

 Score =  109 bits (261), Expect = 9e-23
 Identities = 63/186 (33%), Positives = 106/186 (56%), Gaps = 7/186 (3%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYL 368
           ++ +E  +  I ++ +D YG++D LVN  GI +  T IE  ++ +++RLM+ NV+S++  
Sbjct: 56  NVLQEERVNDIFQQIVDKYGRIDGLVNALGIAQAATPIEQVTMDEWNRLMDVNVKSLFIT 115

Query: 369 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
               VP +  + KG          +R  PG+ AY  SK + + FTR +A+ELAP  +RVN
Sbjct: 116 AKAVVPFMKKQQKGSIVTIASISAVRPRPGLQAYIASKGAAESFTRGLAIELAPNQIRVN 175

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTK-----ETHALGRPGKPDEVAATIAFLASDL 710
            ++PG    + Q  G  + +   A +E+TK     ++  LGR  KP ++A  +++L SD 
Sbjct: 176 TIHPGP--ADTQMLGQFAAQ--GADVEQTKQSVFVQSVPLGRLVKPSDIAGAVSYLLSDA 231

Query: 711 ASNITG 728
           AS +TG
Sbjct: 232 ASMVTG 237


>UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Nocardioides sp.
           (strain BAA-499 / JS614)
          Length = 258

 Score =  109 bits (261), Expect = 9e-23
 Identities = 65/219 (29%), Positives = 110/219 (50%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L+  GA + +     E+ ++ V+   D     +++ A++   +++E  I K +  YG L+
Sbjct: 28  LASEGAAVGVLDLRAESAEETVAAIVDSGGRAIALAANVADSAEVEAAIAKVVAEYGGLN 87

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXG 437
           VL NNAG    G++ + +   ++R  + N +  +  +  AVPHL  S  G          
Sbjct: 88  VLYNNAGCDSRGSVADATDEDWERAFSVNAKGTFVCSRAAVPHLTASGGGAIVNQGSVAA 147

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQY 611
           +   P   AY  +K +V   TR +A++LAP+ +RVN + PG + T L         +   
Sbjct: 148 LVGVPNFAAYCAAKGAVVALTRSMAIDLAPRKIRVNVICPGTVFTPLMEPMLRARGDGDL 207

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            A L +T   + +GR G P+E+A   AFLASD +S +TG
Sbjct: 208 EAGLAKTLVKYPIGRLGTPEEIARVAAFLASDDSSFLTG 246


>UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 284

 Score =  109 bits (261), Expect = 9e-23
 Identities = 78/244 (31%), Positives = 125/244 (51%), Gaps = 16/244 (6%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSI 185
           F+GKVV                 +  GA++ L GR+ ++++K  K C +  +     L  
Sbjct: 6   FSGKVVLISGSSKGIGQATAVKFAAEGAKIVLNGRSADDVEKTRKLCMEVGAKPWDLLPT 65

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE---TGTIE-NTSLAQYDRLMNTNVR 353
             D+T E  ++ ++   I ++GKLD+L+NNAG +E   TG       +   DR  N+N +
Sbjct: 66  VGDITNEDFVKMMVNTVIHNFGKLDILINNAGTLEVDMTGKEGWEMGVDVMDRSWNSNFK 125

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP-GVLA---YNISKASVDQFTRCVALEL 521
           S+  LT  A+PHL+++KG          + S P GV++   Y + KA++DQ +R +A E 
Sbjct: 126 SVLMLTQAAMPHLIKTKGDIVNVSTF--LSSGPIGVMSMPYYAVPKAALDQMSRSMAHEY 183

Query: 522 APKGVRVNCVNPGVILTELQRR----GGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 689
             KGVR+N VNPG++ T    R    G  +  +   +++   E   LGR  +  +VA TI
Sbjct: 184 MLKGVRLNTVNPGLVSTSFFARLPGVGDDNARKMENYVQSKTEYIPLGRVCQASDVAETI 243

Query: 690 AFLA 701
            FLA
Sbjct: 244 LFLA 247


>UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase family
           oxidoreductase, putative; n=3; Pezizomycotina|Rep: Short
           chain dehydrogenase/reductase family oxidoreductase,
           putative - Aspergillus clavatus
          Length = 249

 Score =  109 bits (261), Expect = 9e-23
 Identities = 65/186 (34%), Positives = 98/186 (52%), Gaps = 2/186 (1%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVR 353
           +++ AD++K  DI +++K T+D +GK+DVLV NAG++ + G + + +   +D L   NVR
Sbjct: 57  IAVQADVSKREDIARLVKTTVDRFGKIDVLVLNAGLLWQKGDLLSITEQDFDTLFAANVR 116

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALELAPK 530
           S  +    A PHL E                  P  L Y  SK +V+Q TR +A +L  +
Sbjct: 117 SPLFTIQEAAPHLTEGGRVMLFSTSLAAFSGVTPNYLLYAASKGAVEQMTRVLAKDLGRR 176

Query: 531 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 710
           G+ VN + PG I T+    G  + EQ          T   GR GKP+EVAA + F+ASD 
Sbjct: 177 GITVNTIAPGPIGTDAYFVG--NNEQMVQLQSNLAPT---GRLGKPEEVAAVVNFIASDQ 231

Query: 711 ASNITG 728
           +  + G
Sbjct: 232 SQWVNG 237


>UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Methanoregula boonei 6A8|Rep:
           Short-chain dehydrogenase/reductase SDR - Methanoregula
           boonei (strain 6A8)
          Length = 253

 Score =  109 bits (261), Expect = 9e-23
 Identities = 64/187 (34%), Positives = 100/187 (53%), Gaps = 1/187 (0%)
 Frame = +3

Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 350
           S ++I AD+T E +++++ ++  + YG+LD+LVNNAGI++   +  T + +Y  +M+ N 
Sbjct: 62  SAMAIRADVTCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNC 121

Query: 351 RSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527
           +  +  T  A   ++  K G         G+    G  AY  SK+ V  FT+C A EL  
Sbjct: 122 KGTFLCTQHAAKIMVRQKAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAKELGA 181

Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
             + VN V PG I T+      L+ +  +   E   +  ALGR G PD+VA  I FL SD
Sbjct: 182 FNITVNAVAPGFIDTD------LTADTRSQVKEDILKNIALGRIGTPDDVAKVIVFLGSD 235

Query: 708 LASNITG 728
           LA  ++G
Sbjct: 236 LAGYVSG 242


>UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1;
           Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent
           epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1
          Length = 263

 Score =  108 bits (260), Expect = 1e-22
 Identities = 67/185 (36%), Positives = 99/185 (53%), Gaps = 3/185 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSI 359
           +TAD+  E D+E +++  +  YG+LD   NNAG  +    IE T+  +YD +M TNVRS 
Sbjct: 60  VTADVLSERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTN-DEYDTVMATNVRSA 118

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           ++     +  +L   G           +R+ PG+ AY+ SKA +   TR VA+E A K +
Sbjct: 119 FWCMKYQLKAMLAGGGGAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNI 178

Query: 537 RVNCVNPGVILTELQRRG-GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           R N V+PG++ +E+   G  L +    AF         + R G P EVA  +AFL SD A
Sbjct: 179 RANTVSPGIVESEMATAGWRLHDRMGRAF---ASSFQPMNRVGTPQEVAGLVAFLLSDKA 235

Query: 714 SNITG 728
           S +TG
Sbjct: 236 SFLTG 240


>UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=32; cellular organisms|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Methanosarcina acetivorans
          Length = 256

 Score =  108 bits (260), Expect = 1e-22
 Identities = 71/243 (29%), Positives = 116/243 (47%), Gaps = 3/243 (1%)
 Frame = +3

Query: 9   TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
           T  F GKV                  ++ GA ++LT  N    Q V +  +     L+I 
Sbjct: 6   TKQFLGKVAFVTGGATGIGQATAVAFAREGANVALTYHNQGAEQTVRRIEELGGQALAIK 65

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 365
            D+ +E D++  I+K I  +G+LD   NNAGI  +T       + +++R++ TN+  ++ 
Sbjct: 66  CDVIREEDVKNAIEKIIQTFGQLDYAFNNAGIEGKTVITAEYPVEEWNRVIATNLTGVFL 125

Query: 366 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
                +P +L +  G         G+  FP +  Y  SK  V   T+  AL+ A   +R+
Sbjct: 126 CMKYEIPQMLKQGAGAIVNCSSGAGLTGFPDISPYVASKHGVVGLTKTAALDYAKSNIRI 185

Query: 543 NCVNPGVILTE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           N V PG+  T  ++R  G + E Y    E+  E   +GR G+P+E+A  + +L SD AS 
Sbjct: 186 NAVCPGMTDTPMMERYSGGTPEGY----EKIIEQEPIGRMGRPEEIAIAVLWLCSDAASF 241

Query: 720 ITG 728
           +TG
Sbjct: 242 VTG 244


>UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
           dehydrogenase/reductase SDR - Caldivirga maquilingensis
           IC-167
          Length = 248

 Score =  108 bits (260), Expect = 1e-22
 Identities = 68/208 (32%), Positives = 109/208 (52%), Gaps = 2/208 (0%)
 Frame = +3

Query: 111 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 290
           +TG+  E  ++V K        +++  D+T     E++ +   D YG +D+LVNNAGI  
Sbjct: 38  ITGKENEVAEEVRK---LGGQGMALRLDVTDGKMAEEVARTVFDKYGHIDILVNNAGIYP 94

Query: 291 TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG-IRSFPGVLA 464
                  +   + R++N N+  ++ +T   VP++++ K G         G +  F G+  
Sbjct: 95  FKPFMEMTFNDWYRVINVNLNGVFNVTRAVVPYMVKQKNGRIINIASIAGAVMGFMGLTH 154

Query: 465 YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETH 644
           Y+ SKA +  FTR +ALELA  G+ VN + PG I T     G  SEEQ    +       
Sbjct: 155 YSASKAGIVGFTRALALELARYGITVNAIAPGAINTPGAATG--SEEQVRMMINAI---- 208

Query: 645 ALGRPGKPDEVAATIAFLASDLASNITG 728
            +G+ G P+++A+ +A+LASD AS ITG
Sbjct: 209 PMGKLGTPEDIASAVAYLASDEASYITG 236


>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
           n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
           TM_0325 - Thermotoga maritima
          Length = 251

 Score =  108 bits (260), Expect = 1e-22
 Identities = 72/241 (29%), Positives = 116/241 (48%), Gaps = 2/241 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 188
           MNF GKVV                 ++ GA++++   + E  ++  +         + I 
Sbjct: 1   MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
            D+ K  D E+I+KKT++ +G+LD+LVNNAGI+  G IE TS   +D+ M  NV+  + L
Sbjct: 61  GDVAK--DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118

Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           +  AV  +  +  G         G+   P    Y++SKA++   TR +A++    G+RVN
Sbjct: 119 SKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVN 178

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            V PG   +E       +       L++      + R GK +E+A  I F A D A  +T
Sbjct: 179 AVCPGTTQSEGLMARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEAGFMT 238

Query: 726 G 728
           G
Sbjct: 239 G 239


>UniRef50_Q8R9W0 Cluster: Dehydrogenases with different
           specificities; n=4; Bacteria|Rep: Dehydrogenases with
           different specificities - Thermoanaerobacter
           tengcongensis
          Length = 247

 Score =  108 bits (259), Expect = 2e-22
 Identities = 69/218 (31%), Positives = 120/218 (55%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTG-RNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 257
           L+K G  +++T  ++ ++ ++V ++  K     L+I  D++K  ++EK ++K I+ +G +
Sbjct: 25  LAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVSKYHEVEKAVEKVIEEFGSI 84

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 434
           DV+VNNAGI +   I      ++D++++ N++  + +   A  ++++  KG         
Sbjct: 85  DVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIKFASKYMIKKRKGKIINISSVV 144

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G+    G   Y  SKA +   T+ VA ELA +G+ VN V PG I T++     L E+   
Sbjct: 145 GLMGNVGQANYAASKAGIIGLTKSVAKELASRGITVNAVAPGFIETDM--TNVLKEDIKE 202

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A L    ++  L R GKP+EVA  +AFLAS  +  ITG
Sbjct: 203 AML----KSIPLKRAGKPEEVAEVVAFLASSASDYITG 236


>UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 260

 Score =  108 bits (259), Expect = 2e-22
 Identities = 71/218 (32%), Positives = 113/218 (51%), Gaps = 7/218 (3%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           GA + +  RN +N+ +  +       T    I   +    D +K++  T+  +GK+++LV
Sbjct: 34  GASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILV 93

Query: 270 NNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIR 443
           NN GI    G I   S   +D+L   NV++ + +T L  PH+  E  G           +
Sbjct: 94  NNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYK 153

Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR---RGGLSEEQYA 614
           S PG+ AY ++K ++   TR +A+ LA   +RVN + PGVI T++ +    GG   E+  
Sbjct: 154 SPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKEL 213

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             ++      ALGR G PD+ A T+A+LASD +S ITG
Sbjct: 214 TDIQEI----ALGRLGVPDDCAGTVAYLASDDSSYITG 247


>UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio
           bacteriovorus|Rep: Oxidoreductase - Bdellovibrio
           bacteriovorus
          Length = 321

 Score =  107 bits (258), Expect = 2e-22
 Identities = 72/216 (33%), Positives = 110/216 (50%), Gaps = 2/216 (0%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTID-HYGKLDV 263
           SK G  + L GRN E LQ V+  C   AS +S   DL+ E+ + K + + +     +++ 
Sbjct: 96  SKNGYFVYLMGRNKERLQDVALKCRSGASIVS--CDLSDEAALNKRLGEVMGAKIHRVEC 153

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX-GI 440
           +VNNAGI E+ T E+ S   + R    N+     +     P+  E  G          G+
Sbjct: 154 VVNNAGIYESNTTESGSDELWSRQFEVNMLGPLRIVRAFFPYFKEQGGGSIVNISSTLGL 213

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
           R      AY+  KA++  +T  +ALE  P  +R NCV PG++ T + +   L E+Q  A 
Sbjct: 214 RPQGPTSAYSAVKAALVNWTESLALEGGPLNIRANCVCPGLVDTPIHQFHALPEDQKKAT 273

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           L++      LGR GKP+++A  + FL SDL+S  TG
Sbjct: 274 LDKMGGLQPLGRIGKPEDIARAVYFLGSDLSSWTTG 309


>UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Ralstonia eutropha JMP134|Rep: Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 272

 Score =  107 bits (258), Expect = 2e-22
 Identities = 68/219 (31%), Positives = 118/219 (53%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA++++   NV+   +V+   D      ++I AD++K++D E + ++T++ +G +D
Sbjct: 27  LAREGARIAVVDLNVDAATRVASSIDPDGKRAIAIRADISKKADTEAMARQTLEAFGTID 86

Query: 261 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 434
           +LVNNAG+     +  + +   +DR+M  N + I +     +P +  + KG         
Sbjct: 87  ILVNNAGVGGASALACDVTEENWDRVMGVNAKGILFCCQAVIPAMKAQGKGKIVNIDSIA 146

Query: 435 GIR-SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
           GIR ++   + Y  SK +V   T+ +A ELA + + VN V PG ILT        +E++ 
Sbjct: 147 GIRMAYFSSVDYTASKHAVTGLTQHLAWELADQRINVNAVCPGGILTPAIEAYASAEKRE 206

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A      + T  LGR  KP+E+   ++FLASD A  ITG
Sbjct: 207 ALI----RRTVPLGRFCKPEEIGEAVSFLASDRADMITG 241


>UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Novosphingobium aromaticivorans DSM
           12444|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Novosphingobium aromaticivorans (strain DSM
           12444)
          Length = 246

 Score =  107 bits (258), Expect = 2e-22
 Identities = 67/211 (31%), Positives = 110/211 (52%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA+L++TGRN E L+ V+++ D     L I +D+   +D E+ +++  D  G +DVL  N
Sbjct: 29  GAKLAITGRNAETLRAVAEELD----ALCIRSDMGDLNDTERALEEIEDALGGIDVLFVN 84

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG+     + + +   +D++ + N+R  ++    A+P L+   G          + + PG
Sbjct: 85  AGVGGFAMVPDVTPEFWDQIHSVNLRGAFFAIQRALP-LMRDGGSIVITGSIGSMAAVPG 143

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
            +AY  +KA +    R V  EL P+ +RVN V+PG   TE+ +R   S E+     +   
Sbjct: 144 NVAYAAAKAGLRAMARIVGKELLPRRIRVNMVSPGPTDTEIFKRDA-SAEEIQGMKDMLS 202

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
               +GR G  +EVA  + FLAS  AS I G
Sbjct: 203 SVVPIGRMGTSEEVARAVLFLASAEASFING 233


>UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Clostridium
           phytofermentans ISDg
          Length = 258

 Score =  107 bits (258), Expect = 2e-22
 Identities = 63/220 (28%), Positives = 113/220 (51%), Gaps = 6/220 (2%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           +K GA ++L  R +E L +V  + +K     +++  D+T E  ++  ++  ID +G +D+
Sbjct: 30  AKAGADVALLARRIEKLNEVKAEIEKIGRKVVAVGCDVTNEESVKTAMQTVIDTFGHIDI 89

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGI 440
           L+NNAGI   G +++ S+  +D+  +TNV+ I+  +   VP + E   G          +
Sbjct: 90  LLNNAGIAVRGGVDSMSVEDWDKSYDTNVKGIFLASKYVVPQMKERGYGKIINIASVNAV 149

Query: 441 --RSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
               F   +  +YN SKA+V   TR +A   A  G+ VN + P +  +E+        E+
Sbjct: 150 VADKFDAFIRHSYNSSKAAVVGLTRGMAASYARYGITVNAIGPALFESEMTSDTLFKSEE 209

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              FL +    +  GRPG+  E+  T+ +L+SD +S + G
Sbjct: 210 ---FLNKYNTMNPAGRPGRKGELNGTVLYLSSDSSSYVQG 246


>UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacillus|Rep: Short-chain dehydrogenase/reductase
           SDR - Bacillus coagulans 36D1
          Length = 260

 Score =  107 bits (258), Expect = 2e-22
 Identities = 65/190 (34%), Positives = 107/190 (56%), Gaps = 6/190 (3%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVR 353
           +++  D+T    ++  + KT+  + +LD++ +NAGI  T   IE+ +   +++ ++TN++
Sbjct: 57  MALEVDVTDPEQVKTAVDKTVREWDRLDIVFSNAGINGTVAPIEDLTPDDWEKTLSTNLK 116

Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP--GVLAYNISKASVDQFTRCVALELAP 527
             + LT  A+PH+    G         G R F   G+ AY+ SKA    F +  ALELA 
Sbjct: 117 GTFLLTKYAIPHMKNRGGSIIITSSINGNRIFSNIGMSAYSSSKAGQVAFMKMAALELAR 176

Query: 528 KGVRVNCVNPGVILTELQRRGGLSE--EQYAAFLERTKETHAL-GRPGKPDEVAATIAFL 698
             +RVN V PG I T++++    +E  E+    +E  +    L GRPGKP+EVA  + FL
Sbjct: 177 YKIRVNAVCPGAIETKIEQNTNRTEELEKVQIPIEFPEGDQPLSGRPGKPEEVADLVLFL 236

Query: 699 ASDLASNITG 728
           ASD +S+I+G
Sbjct: 237 ASDDSSHISG 246


>UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=9; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
           sp. (strain RHA1)
          Length = 249

 Score =  107 bits (257), Expect = 3e-22
 Identities = 69/212 (32%), Positives = 109/212 (51%), Gaps = 3/212 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA L L  R+ E L   VS+  +  A  + +  D+T     + ++ + +  +G LD+LVN
Sbjct: 30  GAHLLLADRDEERLAAAVSRYSEGEAKAVGVVVDVTDPDQTKMMVDRCLAEFGALDILVN 89

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 449
            AG++    +    +A +D +++ ++RS++     AVPH+L +  G         GI+  
Sbjct: 90  CAGLLTEVPLAEMDVATWDEMISVDLRSVFLCCRWAVPHMLAQGSGRIINISSQLGIKGG 149

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
            G++ Y  +KA V   TR +A ELAP GV VN + PG + T L    G++E+       +
Sbjct: 150 VGLVHYCAAKAGVIGLTRALARELAPSGVLVNAIAPGPVWTPL--FAGITED-----WRQ 202

Query: 630 TKETH-ALGRPGKPDEVAATIAFLASDLASNI 722
            KE    LGR G P E+A T   LASD   N+
Sbjct: 203 AKEAELPLGRFGLPHEIAPTAVLLASDPGGNL 234


>UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Solibacter
           usitatus (strain Ellin6076)
          Length = 249

 Score =  107 bits (257), Expect = 3e-22
 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 1/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ +TGRN   ++    +    A  + + +D T   D++ +  K  + +GK+DVL  N
Sbjct: 30  GARVIVTGRNPATIKAAQAELGDNA--IVVPSDATSLPDMDALATKVKETFGKIDVLFVN 87

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG       E  + A YD ++N N +  Y++     P L+              +++ P 
Sbjct: 88  AGYGHFVPFEAVTEAVYDEMLNLNAKGPYFIVQKLAP-LMPEGSSVVFTTSIANVKAVPT 146

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVI-LTELQRRGGLSEEQYAAFLERT 632
           + AY  +KA++   TR +A EL P+G+RVN V PG I  T++  R G+ +E       + 
Sbjct: 147 LSAYGAAKAALRAMTRSIAAELLPRGIRVNAVTPGPIGATDVMHRLGMPKEAQDQVYLQM 206

Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728
            E+  + R G+P+E+A  +AFLA D A+  TG
Sbjct: 207 AESVPMKRLGRPEEIAKAVAFLAID-ATFTTG 237


>UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Sphingomonadaceae|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 266

 Score =  107 bits (256), Expect = 4e-22
 Identities = 67/188 (35%), Positives = 98/188 (52%), Gaps = 6/188 (3%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ-----YDRLMNTN 347
           I  +L K  +I+ +++KT DH+G +DVL NNA I ET   + TS+       +D +   N
Sbjct: 61  IACNLRKAHEIKVLMQKTADHFGGIDVLHNNAAIHETDLTDKTSIEDLPEEIWDAVYEVN 120

Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELA 524
           +++++  T  AVP L  SKG         G   S+P   AY  +K  V   T+  A++LA
Sbjct: 121 LKALWLTTRYAVPWLKLSKGAAIVNVASTGSFVSYPQAGAYCATKGGVLLLTKATAVDLA 180

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
             G+R NC  PG I T + ++   + E   A +      H + R GKP+EVA    FLAS
Sbjct: 181 KYGIRCNCYCPGAIETPMLQKYLDAAEDKKAIMSVLTGAHLIPRLGKPEEVAKLACFLAS 240

Query: 705 DLASNITG 728
           D +S I G
Sbjct: 241 DDSSFING 248


>UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus
           iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
          Length = 248

 Score =  106 bits (255), Expect = 5e-22
 Identities = 69/216 (31%), Positives = 111/216 (51%), Gaps = 1/216 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L+ LGA + +  R  E+ Q+V++   + A    +  D+TKE + +  + + I+ +G+LDV
Sbjct: 26  LASLGAIVGVAARKDEDAQEVAEMIGE-AHAFPVQLDVTKELEWKTAVDEIINKFGRLDV 84

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGI 440
           LVNNAG ++    + T+L  Y +L+N N   ++      +P +  + KG           
Sbjct: 85  LVNNAGALKRKPFKETTLDDYQQLINVNQLGVFMGMQAVIPQMEKQQKGSIINNVSISAF 144

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
                  AY  +K+SV   ++  A+EL P G+RVN V+PG I T++  +     E   A+
Sbjct: 145 APISQSSAYAATKSSVVAMSKAAAIELGPAGIRVNMVHPGGIKTDMVTQ----TEDVPAY 200

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                    L R G+P E+A  IAFLASD +S  TG
Sbjct: 201 YNSV----PLKRIGQPVEIAKAIAFLASDESSYCTG 232


>UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 296

 Score =  106 bits (255), Expect = 5e-22
 Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 5/220 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGKL 257
           L+  GA +++  R V+ L++ + D         L++  D+  E  + +++++T++  G++
Sbjct: 65  LAAHGADVAVAARTVDELERTAADIRAATGRRCLAVPTDVKDEEQVIRLVRRTVEELGRI 124

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 434
           DVLVNNAG    G + +     +D   + NVR+ Y+ T  A  HL+ +  G         
Sbjct: 125 DVLVNNAGGTRMGPLSSLPTRAWDASFDLNVRAAYFCTREAGRHLVAQRSGAIVNISSDA 184

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G+    G   Y  +KA++  FT   A E    GVR NC+  G + +E        E    
Sbjct: 185 GLHGVRGGAHYASAKAALQMFTTVTAAEWGRYGVRANCLAVGPVASE-----RAVEAWRV 239

Query: 615 AFLERTKETHA--LGRPGKPDEVAATIAFLASDLASNITG 728
           A ++ ++   A  LGRPG P EVA  + F ASD AS ITG
Sbjct: 240 AGIDTSEFNTATPLGRPGTPAEVANAVLFFASDAASYITG 279


>UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Sphingobacteriales|Rep: Short-chain
           dehydrogenase/reductase SDR - Microscilla marina ATCC
           23134
          Length = 273

 Score =  106 bits (255), Expect = 5e-22
 Identities = 59/158 (37%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
 Frame = +3

Query: 90  KLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
           K GA++ +TGRN E L KVS   + +    L I AD + ESD + ++K+TID YGK+DVL
Sbjct: 30  KAGAKVVITGRNNEKLVKVSDMLNIEQIDNLPIVADSSVESDCKMVVKETIDKYGKIDVL 89

Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 446
           +NNAGI          L+  +R+M  N     Y+T  A+P+L +++G         G R 
Sbjct: 90  INNAGISMRAMFAELDLSVIERVMQINFFGTVYITKFALPYLTQTQGSIVGVSSIAGFRG 149

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560
            PG   Y+ SK ++  F   +  EL  K V V    PG
Sbjct: 150 LPGRTGYSASKFAMQGFLESLRTELLKKNVNVLVAAPG 187


>UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL
           DEHYDROGENASE; n=10; Proteobacteria|Rep:
           TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE
           - Brucella melitensis
          Length = 262

 Score =  106 bits (254), Expect = 6e-22
 Identities = 68/220 (30%), Positives = 115/220 (52%), Gaps = 6/220 (2%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
           +K GA++ +  R+    ++V+ +    A  L++ AD++KE+D++  ++  +  +GK+D+L
Sbjct: 36  AKGGAKVVIVDRDKAGAERVAGEIGDAA--LAVAADISKEADVDAAVEAALSKFGKVDIL 93

Query: 267 VNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXXG 437
           VNNAGI  +    E     ++DR++  NVR +Y +T   +PH  E  +KG          
Sbjct: 94  VNNAGIGHKPQNAELVEPEEFDRIVGVNVRGVYLMTRKLIPHFKENGAKGQECVILNVAS 153

Query: 438 I---RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
               R  P +  YN +K  V   T+ +A+ELAP  +RV  +NP  +  E         E 
Sbjct: 154 TGAGRPRPNLAWYNATKGWVVSVTKALAIELAPAKIRVVALNP--VAGETPLLTTFMGED 211

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                ++ +++  +GR  KPD++A   AFL S  AS ITG
Sbjct: 212 SEEIRKKFRDSIPMGRLLKPDDLAEAAAFLCSPQASMITG 251


>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Leptospira interrogans
          Length = 254

 Score =  106 bits (254), Expect = 6e-22
 Identities = 71/220 (32%), Positives = 113/220 (51%), Gaps = 5/220 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE---KIIKKTIDHYGK 254
           L+K GA L +   N E+ +  + +  K     +I    T  SD++   K I+  +D +G 
Sbjct: 26  LAKAGANLVIADLNEESSKATADEISKQTGVKAIGIG-TNVSDVDSAAKAIQACVDEFGS 84

Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXX 428
           +D+LVNNAGI +   +      Q+D ++  N+   +  T  A+  ++++   G       
Sbjct: 85  VDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCTQAAIKFMMKNPNGGSIINLSS 144

Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
             G+    G   Y+ SKA V  FT+ VALE+A + VR N + PG I TE+     + E+ 
Sbjct: 145 IAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVRCNAIAPGFIATEM--TDAIPEKI 202

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             A +        L R G+P+++A TIAFLASD++S ITG
Sbjct: 203 RTAMVAAI----PLKRAGQPEDIANTIAFLASDISSFITG 238


>UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase
           precursor; n=2; Clostridium difficile|Rep: Probable
           short chain dehydrogenase precursor - Clostridium
           difficile (strain 630)
          Length = 245

 Score =  106 bits (254), Expect = 6e-22
 Identities = 62/191 (32%), Positives = 103/191 (53%), Gaps = 1/191 (0%)
 Frame = +3

Query: 159 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLM 338
           +K  S     A+++   D+E ++   I  +G LDVLVNNAG+ +     + +   +D +M
Sbjct: 50  EKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMM 109

Query: 339 NTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515
           N N++  +Y + +A+ +++ E KG         GI      + Y+I+KA +   T+ +A 
Sbjct: 110 NINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK 169

Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695
           E+ P  +RVN + PGVI T++    G +EE   A +E T     L R G P+++A    F
Sbjct: 170 EVGPSNIRVNSIAPGVINTDM--LSGYNEEDIDALVEET----PLMRLGTPEDIANCAIF 223

Query: 696 LASDLASNITG 728
           LASD ++ ITG
Sbjct: 224 LASDKSNFITG 234


>UniRef50_P66781 Cluster: Uncharacterized oxidoreductase
           Rv1350/MT1393; n=19; Actinomycetales|Rep:
           Uncharacterized oxidoreductase Rv1350/MT1393 -
           Mycobacterium tuberculosis
          Length = 247

 Score =  106 bits (254), Expect = 6e-22
 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 1/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ L   N+E  +  +K        L++  D+T+  D++ +I+  ++ +G LDV+VNN
Sbjct: 31  GARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGGLDVMVNN 90

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFP 452
           AGI    T+   +  Q+D+++  +++  +  T LA   + E K G         G     
Sbjct: 91  AGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMSSVSGKVGMV 150

Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632
           G   Y+ +KA +   T+  A ELA  G+RVN + PG+I      R  ++E       ++ 
Sbjct: 151 GQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLI------RSAMTEAMPQRIWDQK 204

Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728
                +GR G+P EVA+   FLASDL+S +TG
Sbjct: 205 LAEVPMGRAGEPSEVASVAVFLASDLSSYMTG 236


>UniRef50_Q13GE7 Cluster: Putative short-chain
           dehydrogenase/reductase; n=1; Burkholderia xenovorans
           LB400|Rep: Putative short-chain dehydrogenase/reductase
           - Burkholderia xenovorans (strain LB400)
          Length = 255

 Score =  105 bits (253), Expect = 8e-22
 Identities = 61/186 (32%), Positives = 101/186 (54%), Gaps = 4/186 (2%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
           ++  D+T  + I++++++TID YG++DVLVNN G+   G + + +   +DR  + N++S+
Sbjct: 55  ALLCDVTDPASIDRVVRETIDAYGRIDVLVNNVGVSAPGGVVDMTEEIWDRQFDINLKSV 114

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALELAPKG 533
           + +    +P +   +G             + G   +AY+ SKA++ QFTR  AL  +   
Sbjct: 115 FLMCKAVLPLMDRQRGGNVVNVSSLSALRYSGKPQIAYSASKAALIQFTRMAALMHSEHN 174

Query: 534 VRVNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           VR+NCV PG+I T L +R         Y ++L+R      L + G   +VA   AFLASD
Sbjct: 175 VRLNCVIPGLITTPLVQRLAQQFGGGDYESYLKRRNAQVPLAQEGDAWDVANATAFLASD 234

Query: 708 LASNIT 725
            A  IT
Sbjct: 235 EARYIT 240


>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 262

 Score =  105 bits (253), Expect = 8e-22
 Identities = 61/215 (28%), Positives = 115/215 (53%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L++ GA + L   N    + ++ D    A  +++  D++  +++E ++K  ++ +G++D+
Sbjct: 28  LAREGAHVVLADVNDNGGKSIAADLGPTA--MAVKCDVSSAAEVEALVKAAVERHGRIDI 85

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
           L NNAGI   GT      A+++R++  ++ S+YY    A+PH+              G+ 
Sbjct: 86  LFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYACHFAIPHMPRGSA-IVNTASISGLG 144

Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623
                 AYN +K +V  +TR +A++    G+RVN + PG++ T +    G+  +Q     
Sbjct: 145 GDYRFAAYNAAKGAVVNYTRALAVDHGRDGIRVNALCPGLVETPI--TAGV--QQMPGLR 200

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           E   +   + R  +P+E+A+ +AFLASD AS +TG
Sbjct: 201 EDWLKRIPMERAAQPEEMASVVAFLASDDASYVTG 235


>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
           sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
           B14905
          Length = 252

 Score =  105 bits (253), Expect = 8e-22
 Identities = 65/219 (29%), Positives = 115/219 (52%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L+  GA++ +   N E  ++  K   ++    + + AD++K  D+EK +   ++ YG++D
Sbjct: 25  LASNGAKVVIVDFNKETGEETLKLVKEQGGEGIFVQADVSKSEDVEKYVNAAVETYGRID 84

Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXX 431
           V  NNAG+I+    +   + ++YDR+M+ NV+ + +L +  V  ++E +  G        
Sbjct: 85  VFFNNAGVIQKISPLTEIADSEYDRIMSINVKGV-FLGLKHVIKVMEGQGSGSIINTAST 143

Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
            G+RS   +  Y+ SK +V   T+  +LE   KG+R+N + PG + T L        E  
Sbjct: 144 AGVRSEHSMAVYSASKHAVIGLTKSASLEYVKKGIRINAICPGGVETALTNSVTAMFET- 202

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             ++        +GR  KP+E+A  + FLASD AS +TG
Sbjct: 203 GGYIPEEIPNMRMGRYAKPEELAEMVVFLASDKASYMTG 241


>UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=13; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Arthrobacter sp. (strain FB24)
          Length = 297

 Score =  105 bits (253), Expect = 8e-22
 Identities = 68/180 (37%), Positives = 97/180 (53%), Gaps = 1/180 (0%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYL 368
           DL   +   +++   +   G LD+LVNNAG  +    IE  S  Q+D  + TNV ++++L
Sbjct: 111 DLKDAAVCRELVDTAVRELGGLDILVNNAGKQVAQEDIEEISDEQFDHTLKTNVYAMFWL 170

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
           T  AVPHL  +                P ++ Y  +KAS++ FT+ +A +LAPKG+RVN 
Sbjct: 171 TKAAVPHL-PAGSTIINTTSIQAYNPSPTLVDYATTKASINNFTKGLAQQLAPKGIRVNA 229

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           V PG I T LQ   G  +E   A  E  K+T  LGR G+P E+A    FLAS  +S + G
Sbjct: 230 VAPGPIWTPLQVSSGQPKE---ALPEFGKDT-PLGRAGQPAELAPAYVFLASAESSYVVG 285


>UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=1; Mesorhizobium loti|Rep: 3-ketoacyl-acyl carrier
           protein reductase - Rhizobium loti (Mesorhizobium loti)
          Length = 256

 Score =  105 bits (252), Expect = 1e-21
 Identities = 66/184 (35%), Positives = 97/184 (52%), Gaps = 2/184 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           I  D+++  D E  +   +  +G+LD++V NAGI     IENTS   +DR+M  N+R  +
Sbjct: 56  IGTDISQMRDAEASVALALKRHGRLDIIVQNAGIYPWQLIENTSTDDWDRVMAVNLRGTF 115

Query: 363 YLTMLA-VPHLLESKGXXXXXXXXXGIR-SFPGVLAYNISKASVDQFTRCVALELAPKGV 536
             T  A VP   +  G         G   + PG   Y+ +KA ++ F R  ALE +  G+
Sbjct: 116 NATRAALVPMKAQRSGRMLYTSSITGPHVTSPGHGHYSATKAGINGFIRAAALEFSGYGI 175

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
            VN V PG ILTE      + + + AA+++  +++  LGR G P +VA    FLASD A 
Sbjct: 176 TVNGVEPGNILTE-----AIQQHRGAAYIKNMEDSIPLGRLGSPRDVANAFLFLASDDAG 230

Query: 717 NITG 728
            ITG
Sbjct: 231 YITG 234


>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; Photobacterium
           profundum|Rep: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family - Photobacterium
           profundum (Photobacterium sp. (strain SS9))
          Length = 255

 Score =  105 bits (252), Expect = 1e-21
 Identities = 71/238 (29%), Positives = 115/238 (48%), Gaps = 2/238 (0%)
 Frame = +3

Query: 21  AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 200
           AGKV                  S+ GA L L  RN    Q ++++ +    TL I AD+T
Sbjct: 8   AGKVALISGITSGIGEATARLFSQQGASLVLVARNENKGQMLAEELNAQYPTLFIKADIT 67

Query: 201 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTML 377
           + + ++++ ++T+  +G +D   NNAGI      I  TS   +++++NTN+   + +   
Sbjct: 68  QANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLNR 127

Query: 378 AVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554
            +  +  +  G          + + P   AYN S+ +V   TR  A+E A +GVRVN V 
Sbjct: 128 QLSIMSKQGHGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAAVEYAKQGVRVNAVA 187

Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           PG I T +  R    + Q  A   +  + H +GR G+P EVA    +L SDL+S + G
Sbjct: 188 PGAIDTPIFERSTQKDPQLIA---KYHQAHPIGRIGQPREVAEAALWLCSDLSSFVVG 242


>UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=3; Flavobacteriaceae|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Leeuwenhoekiella blandensis MED217
          Length = 246

 Score =  105 bits (252), Expect = 1e-21
 Identities = 63/212 (29%), Positives = 111/212 (52%), Gaps = 1/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           G ++ + GRN E  ++ + +  +    + I  DL     I K+I + +   GK+DVLVNN
Sbjct: 27  GYKVYIIGRNEEKTRQAADNLGELV--VPIVFDLNNLEAIPKLIDELLQATGKIDVLVNN 84

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR-SFP 452
           AGI         + A++DR+++TNV+S++ ++   V  +  + G           +   P
Sbjct: 85  AGINMKKDFAEVTDAEFDRILHTNVKSVFAISREVVKSMKGNYGGSIVNISSMAAQYGIP 144

Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632
            V+AY  SK +++  TR +A++LA   +RVNCV PG I T +  +   S++Q     +R 
Sbjct: 145 QVIAYTASKTAIEGMTRAMAVDLAQYNIRVNCVAPGFIKTPMTAKALNSDKQRK---DRV 201

Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728
                +G+ G P+++A  + +LA   +  ITG
Sbjct: 202 FSRTPMGKMGAPEDIADAVFYLAGKESKFITG 233


>UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium sp. (strain JLS)
          Length = 255

 Score =  105 bits (252), Expect = 1e-21
 Identities = 70/219 (31%), Positives = 116/219 (52%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA ++++GR+ E   KV ++       L  ITAD+T++ D++++  + I   G LD
Sbjct: 31  LAQAGATVAISGRSAERNAKVVEEAAAEGFALHPITADITRQDDVDRMTAEAISALGHLD 90

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 437
           +LVNNAG        + +  Q+D + + NV++++  ++ A  H+ E   G         G
Sbjct: 91  ILVNNAGTCYHAESWDVTEEQWDSVFDLNVKALWACSLAAGAHMRERGSGSIVNIGSMSG 150

Query: 438 -IRSFPGVL-AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
            I + P +  AYN SKA+V   T+ +A E  P G+RVN + PG   TE      ++    
Sbjct: 151 LIVNRPQMQPAYNASKAAVHHLTKSLAAEWGPLGIRVNALAPGYCKTE------MAPVDK 204

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             F +   +   + R   P+E+A ++ FLASD AS ITG
Sbjct: 205 PEFKQHWIDDTPMLRYAMPEEIAPSVVFLASDAASFITG 243


>UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=4; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase -
           Synechococcus elongatus (Thermosynechococcus elongatus)
          Length = 245

 Score =  105 bits (251), Expect = 1e-21
 Identities = 73/219 (33%), Positives = 113/219 (51%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLT-GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKL 257
           L+K GA + +   R+ E   +V +  ++   T ++I AD++    ++ ++ KT++ YG++
Sbjct: 24  LAKEGATVVVNYARSAEAALEVVQRIEQQGGTAIAIAADVSVPEQVDTLVAKTVETYGRV 83

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434
           DVLVNNAGI     +   SL  +  ++N N+  ++  T      +L+ K G         
Sbjct: 84  DVLVNNAGITRDTLLLRMSLEDWQAVINLNLTGVFLCTRAVSKLMLKQKRGRIINIASVA 143

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G    PG   Y+ +KA V  F++ VA ELA +G+ VN V PG I TE+     L  E   
Sbjct: 144 GQMGNPGQANYSAAKAGVIGFSKTVAKELASRGITVNAVAPGFIATEMTAE--LKAEDIL 201

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASD-LASNITG 728
            F+        LGR G+P EVA  + FLA D  A+ ITG
Sbjct: 202 KFI-------PLGRYGEPTEVAGMVRFLALDPAAAYITG 233


>UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Symbiobacterium thermophilum|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Symbiobacterium thermophilum
          Length = 238

 Score =  105 bits (251), Expect = 1e-21
 Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 1/183 (0%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           +  D+   +  E  +  T+D +G++D+LVNNAG      + +T+ A+++ L+  ++  +Y
Sbjct: 51  LQVDVRDPAACEAAVSGTVDRFGRIDILVNNAGTALEKLLVDTTPAEWNDLVAVHLTGMY 110

Query: 363 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
             T  A+PH+L  + G         GI    G +AY+  KA  + FTR +A E+ P GV 
Sbjct: 111 ACTRAALPHMLSRRYGRIITISSIWGITGAAGEVAYSAVKAGQNGFTRALAQEVGPFGVT 170

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN V PG I TE+     L  E+   +L R      +GR G P+EVAA + FLA   A  
Sbjct: 171 VNAVAPGAIDTEM--NSFLQGEELREWLSRV----PVGRLGTPEEVAALVRFLAGPQAGF 224

Query: 720 ITG 728
           ITG
Sbjct: 225 ITG 227


>UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Geobacter metallireducens GS-15|Rep: Short-chain
           dehydrogenase/reductase SDR - Geobacter metallireducens
           (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 266

 Score =  105 bits (251), Expect = 1e-21
 Identities = 71/219 (32%), Positives = 110/219 (50%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + +T  N E +++           + S+ +D  +E+DI+ +     D +G +D
Sbjct: 37  LAEAGATVLITDINREAIEEAEHRLSSMKCKVKSLVSDAGREADIKSLFSYVADSFGGVD 96

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXX 434
           +LVNNAGI     I + SL Q+  ++  N+ S +  +  A   ++   + G         
Sbjct: 97  ILVNNAGIYPATKILDMSLEQWREVIRINLESAFLCSQEAGRIMVRQGTGGVIVNISSMA 156

Query: 435 GIR-SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
            ++  FPG+  Y  SK  V   TR  ALELAP  +R   V PG ILT    R  L + + 
Sbjct: 157 ALKPCFPGLAHYGASKGGVVNLTRSTALELAPHKIRAVAVVPGGILTG-GVRSNLKQSEE 215

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              L+    T  LG  G+PD++A T+ FLASD A+ ITG
Sbjct: 216 KDSLQSIGATIPLGGFGQPDDIARTVLFLASDSAAYITG 254


>UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 249

 Score =  105 bits (251), Expect = 1e-21
 Identities = 65/218 (29%), Positives = 112/218 (51%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L++ GA  S+   +V   +K + + ++  + + +  D+T+ +++E ++++T + +G+LD+
Sbjct: 26  LAREGA--SVVAADVSGAEKETAEGNE--AIVPLHTDVTRAAEVEALVRETTERFGRLDI 81

Query: 264 LVNNAGI--IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
           L N  G+  I    + +   +++D L+N N++S+      A+P ++   G         G
Sbjct: 82  LCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMKYAIPAMVAGGGGSIVNWSSVG 141

Query: 438 -IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
            + S P    Y  +KA +   TR  A E    GVRVN + PG +        G  E++Y 
Sbjct: 142 ALVSSPNTAVYGATKAGILSMTRAAAREWGRSGVRVNAICPGFVYPTGMTLMG--EKEYP 199

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                     AL RPG PDE+AA  AFLASD AS +TG
Sbjct: 200 QAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTG 237


>UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Candidatus Desulfococcus oleovorans
           Hxd3|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Candidatus Desulfococcus oleovorans Hxd3
          Length = 266

 Score =  105 bits (251), Expect = 1e-21
 Identities = 66/218 (30%), Positives = 114/218 (52%), Gaps = 7/218 (3%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA +++  R +ENL  V+++   K    L + A + +   +  I+++ +  +G++D+LVN
Sbjct: 35  GADVAIVSRKMENLAPVAEEIKAKGKRCLPVAAHVGRMDQLPAIVEQVVAEFGQIDILVN 94

Query: 273 NAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449
           NA       TI       +D ++  N++ +Y+L+  AV  ++E KG          I  F
Sbjct: 95  NAATSPAYATIFEAQEKLWDSIIGLNLKGLYFLSQ-AVARVMEEKGAGGSIINVSSIDGF 153

Query: 450 PG---VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYA 614
                V  Y+ISKA V+  TR +ALELAP  +RVN + PG   T+L       L E++  
Sbjct: 154 APQAQVGIYSISKAGVNMATRSMALELAPHKIRVNAIAPGATRTKLFEGLFAFLPEDERE 213

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             +++  +   LGR   PD++   + +LASD ++ +TG
Sbjct: 214 KQIQQIGQAFPLGRVAVPDDMVGLMLYLASDASAYMTG 251


>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Roseiflexus sp. RS-1
          Length = 246

 Score =  104 bits (250), Expect = 2e-21
 Identities = 69/241 (28%), Positives = 112/241 (46%), Gaps = 2/241 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSIT 188
           M   GKV                  ++ GA +++   N+   +    +  +     L++ 
Sbjct: 1   MRLKGKVAIVTGAGHGIGKATAIAFAREGAHVAVVDINMAGAEATVAEITRLDGRALAVQ 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           AD+++ + +E +++  +   G++DVL+NNAGI     +   +  Q+D ++N N++ ++  
Sbjct: 61  ADVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLVKMTEQQWDAVINVNLKGVWLC 120

Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
                PH+  +  G         G+    G   Y  +K  V   T+  A EL P GVRVN
Sbjct: 121 ARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWARELGPSGVRVN 180

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            V PG I TE+     + E+      ERT     L R GKP+EVAA   FLASD +S +T
Sbjct: 181 AVTPGFIATEMITT--IPEKVIQTVCERT----PLRRLGKPEEVAAVYVFLASDESSFMT 234

Query: 726 G 728
           G
Sbjct: 235 G 235


>UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=3;
           Bacteroidetes|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Polaribacter
           dokdonensis MED152
          Length = 257

 Score =  104 bits (250), Expect = 2e-21
 Identities = 69/241 (28%), Positives = 119/241 (49%), Gaps = 3/241 (1%)
 Frame = +3

Query: 15  NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITA 191
           N +GKV                 L++ GAQ+ ++ RN E   +V+K+  ++   T+ I  
Sbjct: 8   NLSGKVAVITGSSKGIGKAIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLDTIGIAC 67

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 368
            + KE   + ++ KTI+ +G++D+LVNNA I    G IE  S   +D++M+ NV++ + L
Sbjct: 68  HIGKEDQRKNLVDKTIESFGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNVKAPWSL 127

Query: 369 TMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           + L +PH   +K G          +    G+  Y+ SKA++   T+  A E    GV+ N
Sbjct: 128 SNLVLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGKYGVKAN 187

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            + PG+I T+       +E+     L + ++     R G P+E+      LASD  + +T
Sbjct: 188 AICPGLIKTKFSAALWQNEK----ILSKVEKALPSSRMGMPEEMVGLACLLASDAGNYMT 243

Query: 726 G 728
           G
Sbjct: 244 G 244


>UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Shewanella
           pealeana ATCC 700345
          Length = 262

 Score =  104 bits (250), Expect = 2e-21
 Identities = 69/216 (31%), Positives = 107/216 (49%), Gaps = 1/216 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 260
           L+  GA++ + GRN   L  V     +     + + AD++ E+++   I++    YG LD
Sbjct: 33  LAAEGAKVMICGRNQPPLDLVVAQIKQAGGVATAVIADVSNETELVAAIERCASEYGSLD 92

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           ++VNNA     G+IE      +     T+V   ++ T  A+  +  + G         G 
Sbjct: 93  IMVNNAMAFTWGSIEEMDTQAWHENFKTSVDGTFWGTKAAMKLMKSNGGSIINLSSICGE 152

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
              P +  Y+ +KA+V  F+R  A E A   +RVN V P V+ T     G LS    A  
Sbjct: 153 LGTPWMSGYSAAKAAVTNFSRAAAAEGAASNIRVNTVIPAVVETP-ATEGMLSN---ATA 208

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            + T+    +GR G+PDE+A+ IAFLASD AS +TG
Sbjct: 209 RKNTERLIPMGRVGQPDELASVIAFLASDEASYVTG 244


>UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|Rep:
           Glucose 1-dehydrogenase - Thermoplasma volcanium
          Length = 261

 Score =  104 bits (250), Expect = 2e-21
 Identities = 62/185 (33%), Positives = 96/185 (51%), Gaps = 6/185 (3%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D+T E ++++ ++KT   YG++D+LVNNAGI +   +  T    + R+++ NV   Y + 
Sbjct: 53  DVTNEEEVKEAVEKTTKKYGRIDILVNNAGIEQYSPLHLTPTEIWRRIIDVNVNGSYLMA 112

Query: 372 MLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
              +P +L    G            +     AY  SK ++   TR VA++ APK +R N 
Sbjct: 113 KYTIPVMLAIGHGSIINIASVQSYAATKNAAAYVTSKHALLGLTRSVAIDYAPK-IRCNA 171

Query: 549 VNPGVILTEL-----QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           V PG I+T +     +   G  E      +E     H +GR G+P+EVA  +AFLASD +
Sbjct: 172 VCPGTIMTPMVIKAAKMEVGEDENAVERKIEEWGRQHPMGRIGRPEEVAEVVAFLASDRS 231

Query: 714 SNITG 728
           S ITG
Sbjct: 232 SFITG 236


>UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family member
           2; n=64; Eumetazoa|Rep: Dehydrogenase/reductase SDR
           family member 2 - Homo sapiens (Human)
          Length = 258

 Score =  104 bits (250), Expect = 2e-21
 Identities = 66/217 (30%), Positives = 114/217 (52%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + ++ R  +N+ + ++K   +  S   I   + K  D E+++ K ++H G +D
Sbjct: 34  LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 93

Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
            LV +AG+    G+   TS   +D++++ NV+S   L    +P++   +G          
Sbjct: 94  FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 153

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
                 +  YN+SK ++   TR +ALELAPK +RVNCV PG+I T+  +    +E  +  
Sbjct: 154 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 213

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           F    KE H L R G+ ++ A  ++FL S  AS + G
Sbjct: 214 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNG 246


>UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=33; Bacteria|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Shewanella oneidensis
          Length = 254

 Score =  104 bits (249), Expect = 3e-21
 Identities = 61/184 (33%), Positives = 99/184 (53%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           ++I AD T+   I + I++T  H G LD++VNNAGI+   +IEN +L  ++R++NTNVRS
Sbjct: 67  IAIKADSTEPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENLTLEDWERIVNTNVRS 126

Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           ++  +  A  H+ +                F G   Y +SK+++    + +A +L P+ +
Sbjct: 127 VFVASQEAALHMNDGGRIINIGSTNAERIPFVGGAIYGMSKSALVGLAKGLARDLGPRAI 186

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
            VN + PG + T++    G S E         K    LGR GK +E+A+ +AF+A   A 
Sbjct: 187 TVNNIQPGPVDTDMNPDNGDSSEP-------IKAIGVLGRYGKAEEIASFVAFIAGPEAG 239

Query: 717 NITG 728
            ITG
Sbjct: 240 YITG 243


>UniRef50_Q89W00 Cluster: Blr0893 protein; n=7;
           Bradyrhizobiaceae|Rep: Blr0893 protein - Bradyrhizobium
           japonicum
          Length = 279

 Score =  104 bits (249), Expect = 3e-21
 Identities = 70/219 (31%), Positives = 112/219 (51%), Gaps = 8/219 (3%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ + GR +   + ++K     A+ +    D+T E+ ++ +I   +D +G++D L NN
Sbjct: 30  GAKIVIAGRRLPEGEALAKQLG--ANCIFRQTDVTVEAQMQALIALAVDKFGRIDCLFNN 87

Query: 276 AG-IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG-IRS 446
           AG   +TG IE   + ++D  M T VRS+      A P++  +  G         G +  
Sbjct: 88  AGGPAQTGGIEGLEVERFDAAMATLVRSVMLGMKHAAPYMKKQGSGSIINNGSIAGRLAG 147

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GL----SEEQY 611
           F   + Y  +KA+V   T+CVA+EL    VRVN ++PG I T +  +  GL    +E+  
Sbjct: 148 FSSSVVYGAAKAAVIHLTKCVAMELGESNVRVNSISPGAIATGIFGKALGLATSAAEKTP 207

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A   E  K    + R G PD++A    FLASD +S I G
Sbjct: 208 AVMREVYKTAQPIPRAGIPDDIAHAAVFLASDESSFING 246


>UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Pseudomonas fluorescens
           (strain PfO-1)
          Length = 254

 Score =  104 bits (249), Expect = 3e-21
 Identities = 57/183 (31%), Positives = 99/183 (54%), Gaps = 1/183 (0%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           + AD+T++   E+ +   ++ +G+LD+LVNNAGII    + + +   ++R+   N  + +
Sbjct: 61  LVADITQDGAAERAVALAVEQFGRLDILVNNAGIIINKLVIDMTREDWERIQAVNATAAF 120

Query: 363 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
             +  AV  ++ +K G            +FP + AY  SK ++ Q TR +ALE+   G+R
Sbjct: 121 LHSREAVKAMMPNKSGSIVNIASYASYFAFPTIAAYTASKGALAQLTRTLALEVIGHGIR 180

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN V  G ++T +        +   AFL +  E   +GR  +P+E+A  +AF+ASD AS 
Sbjct: 181 VNAVGVGDVVTNILNN---VVDDGPAFLAQHGEAAPIGRAAQPEEIAEVVAFIASDRASF 237

Query: 720 ITG 728
           + G
Sbjct: 238 MVG 240


>UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep:
           Ata4 protein - Streptomyces capreolus
          Length = 256

 Score =  104 bits (249), Expect = 3e-21
 Identities = 64/188 (34%), Positives = 95/188 (50%), Gaps = 1/188 (0%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           A  + +  DL +E      +++ ++ +G+LDVLV NAG      +   S   +DR    N
Sbjct: 63  ARAVPVQGDLAREKACVAAVERVVESFGRLDVLVANAGRHRDALLLRLSEDDWDRHQEAN 122

Query: 348 VRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           ++S Y     A+P +L  + G         G+   PG  AY+ +KA +    R VA E  
Sbjct: 123 LKSAYLCVRAALPSMLRQRHGRIVLVSSVAGLVGSPGQAAYSAAKAGLAGLARTVAHEHG 182

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
             GV  NCV PG+I  +     GLSE +    L+RT    A  R G+P+EVAA +AFL+S
Sbjct: 183 RYGVTCNCVAPGLI-ADTPSHDGLSEARRRQILDRT----AAQRAGRPEEVAAAVAFLSS 237

Query: 705 DLASNITG 728
             A+ +TG
Sbjct: 238 PAAAYVTG 245


>UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9;
           Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas
           sp. (strain NCIMB 9872)
          Length = 250

 Score =  104 bits (249), Expect = 3e-21
 Identities = 70/217 (32%), Positives = 112/217 (51%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + L+  N E   Q V++   +      +  D+T E+     +   +    +LD
Sbjct: 26  LAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENHWTGAVDTILAESDRLD 85

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXG 437
            LVNNAGI+    +++TS  ++DR+   NVRS++  T   +  + ++ KG         G
Sbjct: 86  ALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEPMRKAHKGCIVNVSSIYG 145

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           +   PG  AY  SK +V  FT+  A++LAP  +RVN V+PGVI T + ++   + +   A
Sbjct: 146 LVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVIATPMTQQILDAPQSARA 205

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            L  T     LGR  +P EV+  + FL SD AS + G
Sbjct: 206 LLGPT----LLGRAAQPMEVSQAVLFLVSDEASFVHG 238


>UniRef50_Q5P686 Cluster: Subunit of
           2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH; n=4;
           Proteobacteria|Rep: Subunit of
           2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH - Azoarcus sp.
           (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 248

 Score =  103 bits (248), Expect = 3e-21
 Identities = 60/201 (29%), Positives = 104/201 (51%), Gaps = 4/201 (1%)
 Frame = +3

Query: 138 QKVSKDCDKFAS----TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIE 305
           +KV    D+F+      L   AD++ ++ ++ ++++T++ +G++D+LVNNAG+   G + 
Sbjct: 40  EKVRTTVDEFSRLGHRVLGTVADISNKAAVDGMVQQTVEAFGRIDILVNNAGMERAGALR 99

Query: 306 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKAS 485
             S A +D  ++ N++  +  T     H++E+K                G   Y+ +KA 
Sbjct: 100 KLSEADWDITVDVNLKGTFLCTQAVHGHMVENKHGRIVNIASRAWLGGAGQTPYSSAKAG 159

Query: 486 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGK 665
           V   TR +A+EL   G+ VNCV PG+I T +     L E+     L R       G+ G+
Sbjct: 160 VVGMTRALAIELGRSGITVNCVAPGLIHTPMWEE--LPEKDRNFLLSR----QPTGKLGE 213

Query: 666 PDEVAATIAFLASDLASNITG 728
           PD++A T+ FLA D    +TG
Sbjct: 214 PDDIANTLLFLADDDTGFVTG 234


>UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg -
           Agrobacterium tumefaciens
          Length = 258

 Score =  103 bits (248), Expect = 3e-21
 Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 3/183 (1%)
 Frame = +3

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           ADL        ++K+  D  G+LD+L+NNAGI   G     +  Q+  ++ TNV ++++ 
Sbjct: 68  ADLKTREAACALVKRVADDAGRLDILINNAGIANGGDTPLFTEQQWRDVIATNVETVFWC 127

Query: 369 TMLAVPHLLE-SKGXXXXXXXXXGIRS-FP-GVLAYNISKASVDQFTRCVALELAPKGVR 539
           +  A+P + E  +G         GI S  P   +AYN SKA+V   T+ +A ELA   +R
Sbjct: 128 SQAAIPVMREGGRGAIVNVGSMSGIVSNIPQNQVAYNSSKAAVHMMTKSLASELALDNIR 187

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN V PG I T++ R G +   +   +LE T     + R G+PDE+A  I FLAS+ +S 
Sbjct: 188 VNAVAPGYIDTDMSRGGMVHPVRGPIWLEMT----PMKRFGRPDEIATAILFLASEASSY 243

Query: 720 ITG 728
           +TG
Sbjct: 244 VTG 246


>UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma
           proteobacterium HTCC2207|Rep: Putative dehydrogenase -
           gamma proteobacterium HTCC2207
          Length = 259

 Score =  103 bits (248), Expect = 3e-21
 Identities = 60/169 (35%), Positives = 92/169 (54%), Gaps = 7/169 (4%)
 Frame = +3

Query: 243 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-----G 407
           H+  LD++VN AG+   GTIE   L  +D+ M  N+RS +     A+  +  +      G
Sbjct: 79  HFSGLDIMVNVAGVTLMGTIEELDLETWDKTMAINLRSCFLGCQGAIKLMKSNSAESHGG 138

Query: 408 XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG--VRVNCVNPGVILTELQ 581
                     +++ P ++AYN SKA VD  T+ VAL  A  G  + VN +NPGVI T++ 
Sbjct: 139 SIINMASVSAVKAKPELVAYNASKAGVDMMTKSVALHCAVSGYGINVNSINPGVIETDML 198

Query: 582 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           ++     E   A ++  +  H +GR G+P++VAA   +LASD AS +TG
Sbjct: 199 KKVMSQVEDGDALMDSYRALHPIGRIGQPEDVAAMAVYLASDDASFVTG 247


>UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family precursor; n=1;
           Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family precursor - Syntrophomonas wolfei subsp. wolfei
           (strain Goettingen)
          Length = 252

 Score =  103 bits (248), Expect = 3e-21
 Identities = 73/241 (30%), Positives = 116/241 (48%), Gaps = 2/241 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSIT 188
           M   GKV                 L+  GA++ + GR  E L + V    ++    L+I 
Sbjct: 1   MKLKGKVAVITGGGTGIGRAAAIALAAEGARVVVMGRRPEPLNETVDIVKERGGEGLAIP 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           +D+TK  DIEK   +  + YG+LD+LVNNAG         TSL  +DR+   ++RS++ +
Sbjct: 61  SDVTKIEDIEKARDEVRETYGRLDILVNNAGSALFKPFMKTSLEDFDRIYQVDLRSVFAV 120

Query: 369 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           + L +P +LE   G         G+       AY   K  V Q TR +A EL P+ +RVN
Sbjct: 121 SQLMLPLMLEGGGGSIINIASILGVLGGKSSSAYCAMKGGVVQLTRALAAELGPE-IRVN 179

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
           C+ P  I+T +     LS  +    +++  +   + R   P+++  +I F ASD +  +T
Sbjct: 180 CLCPSHIITPMM-EDELSRIESKGKMDKLTKMFPMKRLAYPEDMTGSILFYASDDSKWLT 238

Query: 726 G 728
           G
Sbjct: 239 G 239


>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
           10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
           family member 10 - Homo sapiens (Human)
          Length = 270

 Score =  103 bits (248), Expect = 3e-21
 Identities = 64/183 (34%), Positives = 95/183 (51%), Gaps = 1/183 (0%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 359
           I  D+T+E D++ ++ +TI  +G+LD +VNNAG        E TS   + +L+  N+   
Sbjct: 59  ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
           Y LT LA+P+L +S+G         G       + Y  +K +V   T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VNC++PG I T L            A +        LGR G+P EV A   FLAS+ A+ 
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237

Query: 720 ITG 728
            TG
Sbjct: 238 CTG 240


>UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenase;
           n=1; Gluconobacter oxydans|Rep: NAD(P)-dependent glucose
           1-dehydrogenase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 266

 Score =  103 bits (247), Expect = 4e-21
 Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 4/241 (1%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--ITA 191
           FAGK V                 ++ GAQ++L GR  + L  V +   K +       T 
Sbjct: 9   FAGKKVLVTGASQGIGEATALRFAEEGAQVALNGRKEDKLIAVREKLPKVSGGEHPIATG 68

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D++KE D+++++ ++I   G LDVLV NAG       E+  L  ++ +M  NV  +    
Sbjct: 69  DISKEDDVKRLVAESIKAMGGLDVLVCNAGYQIPSPSEDIKLEDFEGVMAVNVTGVMLPC 128

Query: 372 MLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
              + + LE+  KG          I   P  L Y+ SK +V    R +ALE A +G+RVN
Sbjct: 129 REVIRYWLENGIKGTIIVNSSVHQIIPKPHYLGYSASKGAVGNIVRTLALEYATRGIRVN 188

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            V PG I+T +        EQY A          + RPG+  E+A  I FLA++ ++ IT
Sbjct: 189 AVAPGAIVTPINMSWIDDPEQYKAVSSHI----PMKRPGESREIADAITFLAAEDSTYIT 244

Query: 726 G 728
           G
Sbjct: 245 G 245


>UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium sp. (strain MCS)
          Length = 266

 Score =  103 bits (247), Expect = 4e-21
 Identities = 70/213 (32%), Positives = 108/213 (50%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA+L +T    E L  ++ +     + +  +  D++ E D  ++I   +D +G+LDVLV 
Sbjct: 43  GARLVVTDIQSEPLLALADELRHAGADVEPVVGDVSVEYDAGRMIGAAVDRFGRLDVLVA 102

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSF 449
           NAGII  G     + A +D +M  + R ++     A+  +L +  G         G+   
Sbjct: 103 NAGIIPLGDALEMTAAGWDEVMAIDGRGMFLCCKFAIEAMLPTGGGAIVCLSSISGLAGQ 162

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
               AY  +K      T+ +A+E A +G+RVN V PG I TE  +R    E   + +L  
Sbjct: 163 KRQAAYGPAKFIATGLTKHLAVEWADRGIRVNAVAPGTIRTERVKRFP-EEPGGSEYLAA 221

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +  H +GR G+P EVA+ I FLASD AS ITG
Sbjct: 222 VERMHPMGRIGEPAEVASAIVFLASDDASFITG 254


>UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Rep:
           Dehydrogenase - Flavobacteriales bacterium HTCC2170
          Length = 254

 Score =  103 bits (247), Expect = 4e-21
 Identities = 61/214 (28%), Positives = 111/214 (51%), Gaps = 3/214 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           G ++++      + +K ++  DK  +  L +  D++ ES +E  ++K    +G++D+LVN
Sbjct: 35  GMKVAILSVGEGSAKKAAESIDKSGTGALGLQCDVSDESSVELALEKINSLFGRIDILVN 94

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR--S 446
           +AGI++  +IE  +   +D++++TN+R  +     ++ +L +SK            R   
Sbjct: 95  SAGILDMSSIEEMTTEHWDKVLSTNLRGTFTTIQKSIKYLEKSKFPRIINISSNSGRMGG 154

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626
           F   +AY+ SK  +   T  +A +LAPKG+ VNC+ PG I       G +S ++    L 
Sbjct: 155 FENGMAYSASKGGIIALTYGLARKLAPKGITVNCIAPGTI------EGDMSAQRSQETLN 208

Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              +   +GR G P+EVAA   + A D +   TG
Sbjct: 209 NLLKRFPIGRFGTPEEVAAAALYYAGDDSGFTTG 242


>UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1;
           Blastopirellula marina DSM 3645|Rep: Putative
           dehydrogenase - Blastopirellula marina DSM 3645
          Length = 251

 Score =  103 bits (247), Expect = 4e-21
 Identities = 68/216 (31%), Positives = 107/216 (49%), Gaps = 5/216 (2%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GAQ+ L  RN E L   +       +  +S  ADL+     E++  +    + ++DVLVN
Sbjct: 24  GAQVWLVARNAEKLATAADSLQSAGTKVMSTVADLSDPGAAEQVGVEVAATWDRVDVLVN 83

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452
           NAG+    +    +  +    +  N+ S Y LT   +P L  ++G           R  P
Sbjct: 84  NAGMARFTSFSEATPDEIQAQVQLNLLSPYLLTQQLLPLLAAAQGNVINISSTSAHRLIP 143

Query: 453 GVLA--YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYAAF 620
           G  A  Y ++K  ++  T+ +ALEL P+GVRVN + PG I T L ++     +EE+   +
Sbjct: 144 GRPASVYAMTKGGLNSLTKALALELGPQGVRVNAIAPGTIKTPLTQKMIASFTEERKKEY 203

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +  ++  ALGR G+P+EVA    +LAS  A   TG
Sbjct: 204 DQFVRQAFALGRLGEPEEVAHLAVYLASVEAKWTTG 239


>UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=3; Planctomycetaceae|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase -
           Blastopirellula marina DSM 3645
          Length = 256

 Score =  103 bits (247), Expect = 4e-21
 Identities = 62/217 (28%), Positives = 110/217 (50%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 260
           ++  GA++++  RN E L       +       + + D+TK   +E ++   ++ + KLD
Sbjct: 35  MASRGAKVAVVARNAEKLADTVAIIEAAGGVAQAYSCDVTKRESVEAVVDAVMEKWEKLD 94

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437
           VLVNNAG+     +   +  ++D ++ TN+R ++  T  A   ++ ++ G         G
Sbjct: 95  VLVNNAGVTRDNLLPVMTDDEWDNVIETNLRGMFLFTRAASKQMMRARFGRIINISSVSG 154

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           +   PG   Y+ SKA +  FTR ++ EL  + V VN + PG I +++ +  G       A
Sbjct: 155 LMGNPGQTNYSASKAGMIGFTRSLSRELGKRKVTVNAICPGFIESDMTKALG------PA 208

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            ++  K+     R GKP+E+A  + FLAS  A+ ITG
Sbjct: 209 VMDEVKKRIPAQRMGKPEEIADGVLFLASPQAAYITG 245


>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
           bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
           bacterium HTCC2150
          Length = 279

 Score =  103 bits (247), Expect = 4e-21
 Identities = 69/215 (32%), Positives = 112/215 (52%), Gaps = 4/215 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA + +   N E L +  +D  +F   +S +  D+TK  +++ ++   + +YG LDV++N
Sbjct: 48  GANVVMADVNAEKLAESVQDLIEFDGAVSSMVCDVTKRENLQALVGLAVSNYGNLDVMIN 107

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESK-GXXXXXXXXXGIRS 446
           NAGI +       S  +YD +M+ N+R  +  T +A   ++ + K G          + +
Sbjct: 108 NAGIAKVQDFLEISDDEYDAVMDVNLRGAFIGTQIAGKQMIAQGKGGVIINMSSINALVA 167

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL-SEEQYAAFL 623
            P +  Y ISK  ++Q T   A+ LAP  +RV  + PG ILT++     + S E     L
Sbjct: 168 NPMLSTYAISKGGMNQLTNIAAVGLAPHNIRVCGIGPGTILTDMVADVIMTSPEARHNVL 227

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            RT     + R G+P E+A+  AFLASD AS +TG
Sbjct: 228 SRT----PMERCGEPREIASVAAFLASDDASYMTG 258


>UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
           dehydrogenase/reductase SDR - Verminephrobacter eiseniae
           (strain EF01-2)
          Length = 265

 Score =  103 bits (247), Expect = 4e-21
 Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 2/238 (0%)
 Frame = +3

Query: 21  AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADL 197
           AGKV                  +  GAQ+ +   + E  Q   +  ++  A  L + AD+
Sbjct: 14  AGKVALITGAGSGIGRATALLFATEGAQIVVCDLDPEGGQATVRAIEQAGAQALFVQADV 73

Query: 198 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 377
            + +D  + +++T+ H+ +LDVL NNAGI     + +TS A +D +M  NV+SI+ ++  
Sbjct: 74  AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133

Query: 378 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554
           AVP + E   G         G+      ++Y  +K +V   TR +AL+  P+ +RVN V 
Sbjct: 134 AVPVMAEQGGGSIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMALDHGPQRIRVNSVC 193

Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           PG   T + R            L     +  L R G+ +E+A  + FLASD +S +TG
Sbjct: 194 PGDTDTAMLRDEARQLGLPETALVLAGNSRPLMRVGRAEEIAQVVLFLASDRSSFVTG 251


>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=225; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
           cholerae
          Length = 244

 Score =  103 bits (247), Expect = 4e-21
 Identities = 72/240 (30%), Positives = 115/240 (47%), Gaps = 1/240 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           MN  GKV                 L++ GA++  T  +    Q +S         +++  
Sbjct: 1   MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMAL-- 58

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           ++T    IE ++K   D +G +D+LVNNAGI     +      ++  +M TN+ SI+ L+
Sbjct: 59  NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLS 118

Query: 372 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
              +  +++ + G         G     G   Y  +KA V  FT+ +A E+A +GV VN 
Sbjct: 119 KAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNT 178

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           V PG I T++ +   L++EQ  A L +       GR G P E+A+ +AFLAS  A+ ITG
Sbjct: 179 VAPGFIETDMTK--ALNDEQRTATLAQV----PAGRLGDPREIASAVAFLASPEAAYITG 232


>UniRef50_Q46PX5 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
           NAD-dependent epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 253

 Score =  103 bits (246), Expect = 6e-21
 Identities = 61/182 (33%), Positives = 96/182 (52%), Gaps = 3/182 (1%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYL 368
           D+++E D  ++I  T+  +G+LD++V NAGI   +  +E+ S+ Q+ ++++ N+  ++  
Sbjct: 66  DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125

Query: 369 TMLAVPHLLE--SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
             LA+  + +  + G         G    PG  +YN +K  V   TR + +  A  G+RV
Sbjct: 126 NKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSHAQDGIRV 185

Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722
           N V PG + T L  R   +EE  A    R    H +GR G  DEVA  + FLASD AS I
Sbjct: 186 NAVCPGFVATPLIERA--TEEARA----RLVAAHPIGRLGHADEVAKAVLFLASDDASFI 239

Query: 723 TG 728
            G
Sbjct: 240 VG 241


>UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya
           majuscula
          Length = 246

 Score =  103 bits (246), Expect = 6e-21
 Identities = 62/183 (33%), Positives = 99/183 (54%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
           ++  DL + +DIE++ + T   + +LD+LVN+A  ++TG+IE+ S+  + R+   N  + 
Sbjct: 60  AMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFSIHDWQRVFAVN-STA 118

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
            +LT+      L + G          + + PG+ AY  SK S++Q TR  A ELA +G+ 
Sbjct: 119 PFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQLTRVAAWELADRGIT 178

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN V+PG   T+L R G   E      LE+      LGR G+P ++A  +AFL  +    
Sbjct: 179 VNSVSPGPTDTDLLRTGNPPE-----VLEQAIAMTPLGRLGQPKDIADVVAFLVGNDGRW 233

Query: 720 ITG 728
           ITG
Sbjct: 234 ITG 236


>UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5;
           Proteobacteria|Rep: Short chain dehydrogenase -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 278

 Score =  103 bits (246), Expect = 6e-21
 Identities = 76/219 (34%), Positives = 107/219 (48%), Gaps = 8/219 (3%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           G +++++GR  E    ++ +     +    + AD+  E+D+  ++++T+  +G++DV VN
Sbjct: 56  GYRVAVSGRREEAGNALAAELRALGNEAEFLLADVRFEADVRNLVEQTVVRFGRIDVAVN 115

Query: 273 NAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPH-----LLESKGXXXXXXXXX 434
           NAG   +   I   S A Y      NV      TML++ H     L +  G         
Sbjct: 116 NAGTEGQLAPIVEQSAANYAETFGVNVLG----TMLSLKHEMRVMLAQGSGSIINLSSVA 171

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE-LQRRGGLSEEQY 611
           G     G   Y  SK +V+  T+  ALE A  GVRVN V PG + TE L R  G SEE  
Sbjct: 172 GKVGIAGASVYVASKHAVEGLTKSAALEGAAAGVRVNAVAPGPVATEMLDRFVGGSEENK 231

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A FL     T   GR   PDE+A TI FLASD  S +TG
Sbjct: 232 AGFL----ATIPAGRAATPDEIAQTIVFLASDKVSYLTG 266


>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 286

 Score =  103 bits (246), Expect = 6e-21
 Identities = 67/196 (34%), Positives = 100/196 (51%), Gaps = 12/196 (6%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVR 353
           L +  D+T E  +E  +   ++ +G++D LVNNAGI  +TG     S+  +DR++  ++R
Sbjct: 68  LGLGCDVTSEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLR 127

Query: 354 SIYYLTMLAVPHLLES-------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 512
             + ++     H+L++       +G              P   AY+  KA V   TR +A
Sbjct: 128 GTFLMSRAVARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA 187

Query: 513 LELAPKGVRVNCVNPGVILT----ELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVA 680
            E A  G+RVN V PG + T    EL+R+G +     AA   RT     LGR  +P E+A
Sbjct: 188 SEWARAGIRVNAVAPGYVRTALVAELERKGAIDA---AAIRRRT----PLGRMAEPAEIA 240

Query: 681 ATIAFLASDLASNITG 728
             IAFLASD AS +TG
Sbjct: 241 EVIAFLASDRASYVTG 256


>UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;
           n=4; Bilateria|Rep: Dehydrogenases, short chain protein
           13 - Caenorhabditis elegans
          Length = 257

 Score =  103 bits (246), Expect = 6e-21
 Identities = 71/218 (32%), Positives = 114/218 (52%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L   GA + +  R  EN+ + V+    +       TA +  +SD  K+I  T+D + KLD
Sbjct: 31  LGAAGASVVVCSRKKENVDEAVAALRLENIDAHGTTAHVGNKSDRTKLIDFTLDRFTKLD 90

Query: 261 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 434
           +LV+NA +    G +   + +Q+D+L++ NV+S + LT  AVPHL  S +G         
Sbjct: 91  ILVSNAAVNPHYGDLMKVTDSQWDKLLDLNVKSAFELTKEAVPHLEASGRGNVVFVSSVA 150

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G      + AY++ K ++   ++ +AL LA + +RVN + PG+I T+  +     E +  
Sbjct: 151 GYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRVNSIAPGIIQTDFSQVLFSDESEKQ 210

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +L +     A  R G PDE A  +AFL SD AS I+G
Sbjct: 211 KWLSQI----AQRRFGDPDECAEAVAFLVSDEASYISG 244


>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
           Terrabacter sp. DBF63|Rep: Short-chain
           dehydrogenase/redutase - Terrabacter sp. DBF63
          Length = 252

 Score =  102 bits (245), Expect = 8e-21
 Identities = 59/184 (32%), Positives = 96/184 (52%), Gaps = 2/184 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG-TIENTSLAQYDRLMNTNVRSI 359
           + AD+T  + ++ +++  +D YG+LD+  NNAGI  TG  + + ++ Q+D+++  N+  +
Sbjct: 60  VRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTGV 119

Query: 360 YYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           +      +P +L +  G         G  +     AY  SK  V   TR  A+E + KG+
Sbjct: 120 FISMKAEIPQMLAQGGGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAAVEYSDKGI 179

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
           RVN V PGVI T +       EE Y  F +     H +GR G P ++A  +A+L SD A+
Sbjct: 180 RVNAVLPGVIQTPMI---DALEETYPGFKDALLTKHPIGRLGTPHDIAEMVAWLGSDAAA 236

Query: 717 NITG 728
             TG
Sbjct: 237 FATG 240


>UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain
           dehydrogenase/reductase SDR - Rhodopseudomonas palustris
           (strain BisB18)
          Length = 254

 Score =  102 bits (245), Expect = 8e-21
 Identities = 62/187 (33%), Positives = 90/187 (48%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           A  +++  D++   D   ++ + +  +G++DVLVN AG+ E    E T LA +    +TN
Sbjct: 64  AQGIAVAGDISNSEDARAMVGEVVARFGRIDVLVNCAGVAEYRAFEATDLAMFRATFDTN 123

Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527
           V     +   A+PHL    G           R  P    Y  SKA+V   T  +A E  P
Sbjct: 124 VFGTVAMIQAALPHLTAPGGRIINFSSALATRPIPTASIYAASKAAVSALTHALAKEFGP 183

Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           +G+ VN + PGVI TE+     +  E+ AA     K    LGR G+ D+VA    FLAS 
Sbjct: 184 RGITVNAIAPGVIETEM--TAAILAERGAAI----KAMTPLGRIGQTDDVAGLALFLASH 237

Query: 708 LASNITG 728
            A  +TG
Sbjct: 238 DAGWLTG 244


>UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Ralstonia metallidurans CH34|Rep: Short-chain
           dehydrogenase/reductase SDR - Ralstonia metallidurans
           (strain CH34 / ATCC 43123 / DSM 2839)
          Length = 269

 Score =  102 bits (245), Expect = 8e-21
 Identities = 68/223 (30%), Positives = 122/223 (54%), Gaps = 9/223 (4%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           ++LGA++ +  R+  +  + +     +  +  +   D+ +E++I ++  +  +H+G +DV
Sbjct: 36  ARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDV 95

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGI 440
           L +N GI +TG + +T +  +D   N NVRS+   +   +P ++E  +G         G+
Sbjct: 96  LHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGL 155

Query: 441 R--SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           R   +P  L+Y++SKA++ QFTR +A + A  G+R NCV PG+I  +  R      +Q++
Sbjct: 156 RYIGYPH-LSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLI--DTPRIAHTVAKQFS 212

Query: 615 A-FLERTKETHA----LGRPGKPDEVAATIAFLASDLASNITG 728
           A  L+  +   A    + R G   +VA   AFLASD A+ ITG
Sbjct: 213 ADSLDDARAARARQVPMQRMGTAWDVAHACAFLASDAAAYITG 255


>UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Methylobacterium
           extorquens PA1
          Length = 282

 Score =  102 bits (245), Expect = 8e-21
 Identities = 65/240 (27%), Positives = 117/240 (48%), Gaps = 3/240 (1%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITAD 194
           F GKV                  ++ GAQ+++T R  E L+++  + +    + ++I  D
Sbjct: 38  FNGKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRCD 97

Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           ++   D+   + +T++ +G+LD   NNAG+  +   +   +L ++DR+++ N+R  +   
Sbjct: 98  VSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTFVCM 157

Query: 372 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
              +  +L +  G         GIR   G  +Y  SK ++   T+  AL+ A   +RVN 
Sbjct: 158 KHEIAQMLRQGGGVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAALDYAKANIRVNA 217

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           V PG I T +  R    + Q A  LE       +GR GKP+E+A  + ++ SDL + +TG
Sbjct: 218 VLPGNIETPMMERFTGGDIQKAIDLE------PVGRLGKPEEIAEAVLWMCSDLGAFVTG 271


>UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Congregibacter litoralis KT71|Rep: Short-chain
           dehydrogenase/reductase SDR - Congregibacter litoralis
           KT71
          Length = 259

 Score =  102 bits (245), Expect = 8e-21
 Identities = 68/218 (31%), Positives = 104/218 (47%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           ++  GA L LT  N   +  ++ +  +  +   ++  D+T+  D E+ +   +D +G LD
Sbjct: 30  MAAAGASLVLTDINHSAVAALADELGREGTQAAALQHDVTQPGDWERAVALAVDTFGGLD 89

Query: 261 VLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 434
           +LVNNAGI    T + N  L  +  +++ N+  ++     + P L     G         
Sbjct: 90  ILVNNAGIAGDNTDLMNLDLENWHSVLSVNLDGVFLGLRYSGPALERRGGGSVINISSIL 149

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G   FPG   Y  SK +V   ++  ALE AP  +RVN V+PG + T L R      E  A
Sbjct: 150 GKVGFPGAAPYCASKGAVTLLSKSAALEWAPLKIRVNSVHPGFVETPLVRDALAEREDGA 209

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              E     H +GR G   E+A  + FLASD AS +TG
Sbjct: 210 EMAELLVAAHPIGRLGLATEIANAVTFLASDEASFMTG 247


>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Marinomonas sp. MED121|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MED121
          Length = 255

 Score =  102 bits (245), Expect = 8e-21
 Identities = 67/242 (27%), Positives = 114/242 (47%), Gaps = 3/242 (1%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSIT 188
           MNF  +VV                 ++ GA+L+L   NV  L  +  +  ++     S  
Sbjct: 2   MNFKDQVVLITGASGGLGKEAAKQFAQQGAKLALCDLNVAALNDLGTELIEQGYEVFSQP 61

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 365
            D++ E +++  I  T  H+G+LDV +NNAGI  +  T+ +     ++R+M+ NV+ +Y 
Sbjct: 62  CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121

Query: 366 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
                +PH++ +  G         GI   P + AY  SK +V   T+ VA E    G+RV
Sbjct: 122 CMKYQIPHMIKQGGGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVAHEYGRAGIRV 181

Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722
           N V P + +T++  +   + +     L +  +  AL R  +P+EVA  + F      S +
Sbjct: 182 NSVCPYITMTDMVEQHLKTLDNREEVLAKYSKASALRRVAQPNEVAKVMLFACDKNNSYM 241

Query: 723 TG 728
           TG
Sbjct: 242 TG 243


>UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Roseovarius sp. 217
          Length = 256

 Score =  102 bits (245), Expect = 8e-21
 Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 4/220 (1%)
 Frame = +3

Query: 81  FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           FLS+ GA+++L   +V++L   + D       L+I AD++   D ++ + +T++ +G++D
Sbjct: 26  FLSE-GAKVALVDLHVDDLSDAAGDLGNPDDLLTIAADVSSVEDCKRYVAQTVEKFGRID 84

Query: 261 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 434
           V  NNAG+      + +  +  +DR+M  NVR  +      +P +  +  G         
Sbjct: 85  VFFNNAGVEGMVAPLVDQKIEDFDRVMAVNVRGAFLGLQHVLPVMTGQQSGSVINMSSIA 144

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQ 608
           G++  P V  Y  SK +V   TR  A+E+A   VRVN V+P  + T + R    G +   
Sbjct: 145 GLKGSPNVAPYITSKHAVVGLTRAAAIEVAGHNVRVNSVHPSPVNTRMMRSLEEGFNPGH 204

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                ++   T  LGR G+  E+A  + FLASD ++ ITG
Sbjct: 205 GDEVKQQLAGTIPLGRYGESIEIANLVLFLASDESAFITG 244


>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Leptospira interrogans
          Length = 259

 Score =  102 bits (244), Expect = 1e-20
 Identities = 65/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
           ++K G  + L   N E +++ + D  K     TL ++ ++TK  D + +I    + +GKL
Sbjct: 33  IAKEGGDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSCNVTKPEDCDSVIAGVKEKFGKL 92

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434
           D LVNNAG+++       S  ++D +++ N++ ++ +T  A   LL+++ G         
Sbjct: 93  DFLVNNAGVLKDNLFIRMSEQEFDFVLDVNLKGVFLMTKYASKLLLKAESGRIVNISSVS 152

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G+   PG   Y+ SKA V   T+  A E A + V VN V PG + T++     L EE   
Sbjct: 153 GLTGQPGQANYSSSKAGVIALTKVAAREFAGRNVLVNAVCPGYVQTDM--TASLPEEVQK 210

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              +       L RPG   E+A  + F  SD ++ ITG
Sbjct: 211 KLTD--PAFIPLRRPGTQQEIANAVKFFLSDQSNYITG 246


>UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12;
           Alphaproteobacteria|Rep: Dehydrogenase - Bradyrhizobium
           japonicum
          Length = 268

 Score =  102 bits (244), Expect = 1e-20
 Identities = 64/219 (29%), Positives = 111/219 (50%), Gaps = 8/219 (3%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GAQ+    RN    ++ +K   D+     + TAD+++ ++IE ++   +  YG++DVL N
Sbjct: 35  GAQVFCVDRNGTAAEETAKIINDEGGKATAFTADVSRSAEIEAMVAACLKAYGRIDVLDN 94

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452
           N GI E G++   +   +DR+ + N++S Y+     +P ++E  G               
Sbjct: 95  NVGIAEMGSVVEVTEESWDRVFSVNLKSAYFAMKHVIPVMVEQGGGSIINISSIASIRHM 154

Query: 453 GV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQYAAFL 623
           G+  + Y  SKA+++Q TR  A+E A   VRVN + PG++ T + +   GL+       +
Sbjct: 155 GISYVTYGTSKAAMNQMTRTTAIEFARHHVRVNAILPGLMKTPMVEHSAGLAASYAKGDV 214

Query: 624 E---RTKETHA-LGRPGKPDEVAATIAFLASDLASNITG 728
           E   R ++    +G  G   +VA    FLASD +  +TG
Sbjct: 215 EAMWRARDAQVPMGHMGDAFDVANAALFLASDESKYVTG 253


>UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 306

 Score =  102 bits (244), Expect = 1e-20
 Identities = 68/188 (36%), Positives = 96/188 (51%), Gaps = 4/188 (2%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLA---QYDRLMNTN 347
           +++  D+T   DIE++I   +D +GKLDVL NNAG   TG I   + A    +D +M  N
Sbjct: 114 IAVHVDVTSTEDIERMITTAVDRFGKLDVLYNNAGF--TGPIVPLAEAGEDYFDAVMAVN 171

Query: 348 VRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           V+ +Y     A+P +L    G         G+  + G+  Y  +K +V Q TR  AL+ A
Sbjct: 172 VKGVYLGMKAAIPVMLAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAALDYA 231

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
            KG+RVN V PG   T   R+    ++      E       + R G PDE+AA   FLAS
Sbjct: 232 AKGIRVNAVCPGATWT---RQADAEDDSLPP--EGVVPPQPMRRWGMPDELAAAALFLAS 286

Query: 705 DLASNITG 728
           D AS +TG
Sbjct: 287 DDASFVTG 294


>UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1;
           Micromonospora sp. ML1|Rep: NAD or NADP oxidoreductase -
           Micromonospora sp. ML1
          Length = 264

 Score =  102 bits (244), Expect = 1e-20
 Identities = 68/211 (32%), Positives = 103/211 (48%), Gaps = 1/211 (0%)
 Frame = +3

Query: 99  AQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNA 278
           A +   GR    L++++ D     +T  + AD+T+    E ++      +G +  LVNNA
Sbjct: 46  ANVVAVGRREAALRELTGDGGGQVAT--VAADITEPGAAEHVVAAATTRFGTVHGLVNNA 103

Query: 279 GIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGV 458
           G+    T++  S   +DRL+ TNVR+   L   A+PHL E +G          + + PG 
Sbjct: 104 GLARFATLDTASDEDFDRLLATNVRAPAALIRAALPHLREHRGAVVNVSSVGAVLAMPGR 163

Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 638
             Y  SKA+++  TR +A ELAP  VRVN V PG + T +    GL   + A        
Sbjct: 164 SFYGASKAALNSLTRSLARELAP-DVRVNAVLPGPVDTPMWDDMGLDSVKSALLRSSLLA 222

Query: 639 THALGRPGKPDEVAATI-AFLASDLASNITG 728
              LGR G+P E+A  +   L  + +  ITG
Sbjct: 223 ATPLGRFGQPAEIAGWVCGLLDPEFSGWITG 253


>UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Bacillus sp. B14905
          Length = 254

 Score =  102 bits (244), Expect = 1e-20
 Identities = 71/217 (32%), Positives = 110/217 (50%), Gaps = 3/217 (1%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           +K GA++ +T  N ++  +   D   F    L +  D++ E D +K+  + I  + K+D+
Sbjct: 29  AKEGAKIVITDINEQSGNETVSDIQAFGGEALFVLHDVSNEDDWKKVADEAIHTFNKVDI 88

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXG 437
           L NNAGI     +    L+ ++RLM+ NV  + +L M  +  L+  ++KG         G
Sbjct: 89  LFNNAGIYIIKPLAEIELSDWNRLMSINVTGV-FLGMKHIMPLMAKQNKGSVINASSIAG 147

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           +    G + Y  SK +V   T+  A+E AP GVRVN ++PG I T +      S    ++
Sbjct: 148 LTGAAGHVLYGASKGAVRIMTKDAAMEYAPYGVRVNSIHPGYIDTGMADYA--SATTGSS 205

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             E  K    LGR G   EVA T+ FLASD +S  TG
Sbjct: 206 KDELGKNLFPLGRLGSVKEVAQTVLFLASDESSFSTG 242


>UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=8; Yersinia|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Yersinia pestis
          Length = 248

 Score =  101 bits (243), Expect = 1e-20
 Identities = 69/218 (31%), Positives = 107/218 (49%), Gaps = 4/218 (1%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           S++G  +  +GR  E  + +  D  +     L + AD+  ESDI+ +I+ T++ +G LDV
Sbjct: 23  SEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDV 82

Query: 264 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 437
            VN AG + ET  I+  +   +  + NTNV          +P ++E  KG         G
Sbjct: 83  AVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAG 142

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQYA 614
           +   P    Y  SK +++  T+  ALE+A  GVR+N ++PG +  ++  R  G  E    
Sbjct: 143 LVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKK 202

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           AF+E         R    +EVA TI FLA D  + ITG
Sbjct: 203 AFIEMMPNK----RFTTQEEVAHTIVFLAEDNVTAITG 236


>UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Burkholderiales|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 249

 Score =  101 bits (243), Expect = 1e-20
 Identities = 59/216 (27%), Positives = 106/216 (49%), Gaps = 1/216 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + +T  N E  Q  +K   D+  +   I  D+T+E+D+++++ +T+ H+G + 
Sbjct: 27  LAQEGASVVITDINAELAQATAKALQDEGLAAHCIVGDITQEADVQRLVDETVAHFGGVH 86

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           +LVNNAG      +   S   +D +MN  ++  +      +PH +E              
Sbjct: 87  ILVNNAGAPRDKYLVKMSADDWDFVMNVMLKGAFLAARAVMPHFIEQGWGRLINISSRAH 146

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
              P    Y+ +KA +    + +++E    G+  NCV PG + TE+ +    +   Y   
Sbjct: 147 LGNPTQANYSAAKAGLIGMAKALSMEEGRYGITANCVAPGFMETEMVQ----ALPTYETI 202

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            ER      + R G+PD++A  +AFLAS+ A  I+G
Sbjct: 203 KERAVAAQPIKRVGRPDDIADAVAFLASERAGFISG 238


>UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU -
           Streptomyces sp. Tu6071
          Length = 244

 Score =  101 bits (243), Expect = 1e-20
 Identities = 68/213 (31%), Positives = 102/213 (47%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA +++TGR+ +  ++V K   +       I A+L  ES   ++ +  +  +G++DVLVN
Sbjct: 27  GADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAELRGESSARRLAQAAVARFGRIDVLVN 86

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 449
           NAG+   G  E T+ A +D +   NVR  Y+L     P +     G              
Sbjct: 87  NAGVFPFGPTERTTEADFDAVFGLNVRVPYFLVAELAPAMARRGHGAIVNVTTAAAAYGA 146

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
            G+  Y  SKA++   T+  A E  P+GVRVN V PG   TE     G +     A L+R
Sbjct: 147 AGLGLYGASKAALVLLTKAWAAEYGPRGVRVNAVGPGPTRTE-----GTAPR--GAALDR 199

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                   RPG  +E+A  I FLAS+ +S + G
Sbjct: 200 AALAGPARRPGTAEEIAGAIVFLASEQSSFVHG 232


>UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Alteromonadales|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella denitrificans
           (strain OS217 / ATCC BAA-1090 / DSM 15013)
          Length = 246

 Score =  101 bits (243), Expect = 1e-20
 Identities = 59/185 (31%), Positives = 95/185 (51%), Gaps = 1/185 (0%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           L    D++   D+E       + +G +D L+ NAGI +   I + + A +D+ MN NV+ 
Sbjct: 52  LVFKGDVSVNKDLEDFFNTCYELWGGIDTLIANAGIAQPENIADVTEASFDKCMNINVKG 111

Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA-YNISKASVDQFTRCVALELAPKG 533
           +++    ++ +L  +K            +   G+ + Y  +KA+V   TR  A  L P+G
Sbjct: 112 VFFTVQKSLGYL--NKAASIIILSSIQAQRGAGIWSVYGATKAAVRSLTRSFAQALGPEG 169

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           +RVN ++PGV  T +  + G +E+Q A  L +      LGR   P E+A +  FLASD A
Sbjct: 170 IRVNTLSPGVTDTPILTKFGFAEDQLADILAQVSANTPLGRIASPAEIAKSALFLASDNA 229

Query: 714 SNITG 728
           S ITG
Sbjct: 230 SFITG 234


>UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 251

 Score =  101 bits (243), Expect = 1e-20
 Identities = 66/217 (30%), Positives = 112/217 (51%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADLTKESDIEKIIKKTIDHYGKLD 260
           L+  G +++L  R+   L +V+ +        +I  AD+T E  + +  +  +  YGK+D
Sbjct: 27  LAAEGTRIALVSRDEARLNEVAAELIAAGGDAAIFRADVTSEEQVRQAERAILATYGKVD 86

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 437
           +L+NNAG+     +   ++ ++ R+M+TNV + + +    VP +     G          
Sbjct: 87  ILINNAGVNVRKPVVEFTVEEWHRVMDTNVTAAFLMCRSFVPAMSGRGYGRILNMTSIMS 146

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
             S PG +AY+ SK ++   TR +ALELAP+G+ VN ++PG   TE+ +    + E  A 
Sbjct: 147 HVSLPGRIAYSTSKTALLGMTRTLALELAPQGITVNGISPGPFGTEMNKPLMENPETNAQ 206

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           FL     +  LGR GK +E+     +L S+ A  ITG
Sbjct: 207 FL----SSIPLGRWGKVEEIGQLAVYLCSEDAGFITG 239


>UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
          Length = 266

 Score =  101 bits (243), Expect = 1e-20
 Identities = 67/217 (30%), Positives = 103/217 (47%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L+  GA L L  R+   L +V+ +   K      +T DL   + +E   +  +D    +D
Sbjct: 29  LADAGASLILAARDAAKLGEVADEVRAKGRDARIVTFDLADMASVEAAARGLVDEGAPID 88

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM-LAVPHLLESKGXXXXXXXXXG 437
           +LVNN GI E G +  +SL  ++R  + NV +IY L   L+ P      G          
Sbjct: 89  ILVNNGGIAEWGPLHGSSLDHWERTFDVNVSAIYLLCRELSKPMAERGWGRIINFASYVA 148

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
               P + AY  SK +V   TR VA +LAP GV  N + PG+ LT++        ++   
Sbjct: 149 ETGRPNLSAYVASKHAVLGLTRAVAADLAPHGVTCNAIAPGIFLTDMAAPTAGHPQRAKI 208

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           F    ++  A+GR G P E+   + FLAS+ +  +TG
Sbjct: 209 F----RDAIAIGRFGDPAEIVGPVQFLASEASRYVTG 241


>UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Comamonas testosteroni KF-1|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Comamonas testosteroni KF-1
          Length = 249

 Score =  101 bits (243), Expect = 1e-20
 Identities = 60/180 (33%), Positives = 93/180 (51%), Gaps = 1/180 (0%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D++ E   ++++   +DHYG++D LV +AGI   G +E+ +L ++++++  N+       
Sbjct: 58  DVSSEKLTQELVASMLDHYGQIDGLVTSAGISRVGDLESMALQEWEQVLQVNLTGTMLSA 117

Query: 372 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
                H+ + + G         G+   P  LAY  SK +V Q  R +A EL P GVRVN 
Sbjct: 118 RAVASHMKQRRQGSIVAIASINGMLGNPSNLAYCTSKGAVIQMVRSLAAELGPCGVRVNS 177

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           ++PG I T +     L E+      E     H L R GK  EV   +AFL SD++S ITG
Sbjct: 178 ISPGYIHTPMTIM--LDEQPVGQAFE---AMHLLKRAGKSQEVGNAVAFLLSDMSSFITG 232


>UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;
           Cenarchaeum symbiosum|Rep: Short-chain alcohol
           dehydrogenase - Cenarchaeum symbiosum
          Length = 252

 Score =  101 bits (243), Expect = 1e-20
 Identities = 69/242 (28%), Positives = 117/242 (48%), Gaps = 3/242 (1%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           M   GKV                 L++ GA++ L GR  + L+   +      ST SI  
Sbjct: 1   MRLEGKVAVVTGASSDIGASIVRRLAEEGAKVVLLGRRPDALEAARRVSGHEESTASIPC 60

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368
           D+T E  + ++  + ++ YG++D+LVN AG I +        +    ++++ NV  +   
Sbjct: 61  DVTDEGQLAQMADRVVEAYGRIDILVNGAGSIHDPKHFHVMPIMDVKKMIHGNVLGVLLP 120

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGV--LAYNISKASVDQFTRCVALELAPKGVRV 542
           T   +  ++++ G           R+ P V   AY+ +KA+V  FT+ +A+E A + +R 
Sbjct: 121 TRAVLGKMMDTGGVIINIGSISAERAIPRVHLAAYSSTKAAVVMFTKSIAVEYARRNIRC 180

Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722
           NC+NPG++ + +  +  L +      LE   E   L R G P ++A  + FLASD AS I
Sbjct: 181 NCINPGIVDSGM-IKPYLEDPDARRILE---ERQPLKRIGTPADIANAVLFLASDEASWI 236

Query: 723 TG 728
           TG
Sbjct: 237 TG 238


>UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase;
           n=4; Xanthobacter autotrophicus Py2|Rep:
           2-(R)-hydroxypropyl-CoM dehydrogenase - Xanthobacter sp.
           (strain Py2)
          Length = 250

 Score =  101 bits (243), Expect = 1e-20
 Identities = 64/188 (34%), Positives = 95/188 (50%), Gaps = 4/188 (2%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 347
           L + AD+  E D+   I  T++ +G +DVLVNNAGI    E G +  T + Q+D++M  N
Sbjct: 55  LRVRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114

Query: 348 VRSIYYLTMLAVPH-LLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           VR I+      +PH LL+  G          + +FPG  AY  SK +V Q T+ VA++ A
Sbjct: 115 VRGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYA 174

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
             G+R N V PG+I T + +      E     L R  +       G   +VA  + FLA 
Sbjct: 175 GSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEI----GTAAQVADAVMFLAG 230

Query: 705 DLASNITG 728
           + A+ + G
Sbjct: 231 EDATYVNG 238


>UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyces
           avermitilis|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 273

 Score =  101 bits (242), Expect = 2e-20
 Identities = 68/220 (30%), Positives = 113/220 (51%), Gaps = 9/220 (4%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           G  + ++GR  E L+++ ++       L+  +D+      + +++  +  YG+LD LV N
Sbjct: 28  GHHVVISGRRAEPLRRLERE----TGALACPSDVGDPDAADGLVRTALAAYGRLDGLVLN 83

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AGI   G + + SL  +  +M TNV     L   A+PHLL++KG          +R+   
Sbjct: 84  AGIGRGGAVGDVSLEDWHDVMRTNVTGPLLLLRAAIPHLLDTKGAVVAVASVSALRNGAS 143

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL--QRRGGLSEEQ------- 608
            + Y  SKA++ Q  R VA++   +GVR N V P  + +E+  +R    +EE        
Sbjct: 144 NVPYATSKAALLQLCRSVAVDYGRQGVRANIVCPSWVRSEMADRRMARFAEEADLKDGSV 203

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +A+ E T+    LGRPG+P E+A  I++L S  AS + G
Sbjct: 204 ESAYEEATRFL-PLGRPGEPREIAEAISWLLSPAASYVNG 242


>UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Roseiflexus castenholzii DSM 13941|Rep: Short-chain
           dehydrogenase/reductase SDR - Roseiflexus castenholzii
           DSM 13941
          Length = 260

 Score =  101 bits (242), Expect = 2e-20
 Identities = 64/215 (29%), Positives = 102/215 (47%), Gaps = 1/215 (0%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
           ++ G  + +   N++ L K + + D   + L+I  D+     +   I++T+ HYGK+D +
Sbjct: 28  ARAGGSVVIADINLD-LAKATLERDLQGNGLAIQCDVASSESVRAAIEQTLAHYGKIDAI 86

Query: 267 VNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
            NNA I   +  +  TS  Q+D LM TN++S+YY T   +  L  S+G         G+ 
Sbjct: 87  HNNAAISRPSAPLHETSEEQWDALMATNLKSVYYTTFYGIDALKASRGCILNTASMVGVL 146

Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623
                 AY  +K ++   T+ +AL+ A  G+RVN + P  + T L       +   AA  
Sbjct: 147 GQERHAAYVATKGAMIALTKAMALDYASYGIRVNAICPAAVWTPLLHEWVQDQPDPAAAR 206

Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           +     H LG     D VA    FL S+ A  ITG
Sbjct: 207 QFLDGIHVLGYCPDGDVVADAAVFLLSERARFITG 241


>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 253

 Score =  101 bits (242), Expect = 2e-20
 Identities = 64/241 (26%), Positives = 116/241 (48%), Gaps = 2/241 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           ++F GKVV                 ++ GA++ +   +    + V    +   + L +  
Sbjct: 5   LDFTGKVVLITGGATGIGRATALAFAQQGARVVVGDVDDRAAETVRLIEESGGTALFVRT 64

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368
           D+T  +D++++++ T+D YG L V  NNAGI+  TG +   S   +DR +  +++ ++  
Sbjct: 65  DVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPTGPLAEQSEDDFDRTIAVDLKGVFLA 124

Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
               + H+  +  G         G+ + PG+  Y  +K  V   TR  A++ A  GVRVN
Sbjct: 125 LKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAAIDYAAAGVRVN 184

Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            + PG++ T + +      ++ A   +    ++   R   P+E+A T+ FLASDLAS  T
Sbjct: 185 ALAPGLVDTPMTK----VWQEDAEIWDAVAASNGFHRAAAPEEIAGTVLFLASDLASFTT 240

Query: 726 G 728
           G
Sbjct: 241 G 241


>UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Nocardioides sp. JS614|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 244

 Score =  101 bits (242), Expect = 2e-20
 Identities = 63/188 (33%), Positives = 100/188 (53%), Gaps = 4/188 (2%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 347
           LS+ AD+T  + +E  ++  +D +G++D+LVNNAGI    E     +T + Q+D +   N
Sbjct: 49  LSLEADVTDPAGVESAVEAILDAFGRVDLLVNNAGITGSAEATVCHDTPVEQWDLVHAVN 108

Query: 348 VRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           VR  +  T   +P +L  K G         G+ +FPG  AY  SK +   FTR +A++ A
Sbjct: 109 VRGPFLCTRAVLPTMLIQKSGHVITVASVAGLVAFPGRCAYTASKGAAIAFTRSLAVDYA 168

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
             GVR N + PG++ T +  +  L   +  A +E       LGR  KP+++A  +  LAS
Sbjct: 169 AAGVRANAICPGMVETPM-TQWRLDVPELRAQVE---SKIPLGRVAKPEDIADAVVALAS 224

Query: 705 DLASNITG 728
           D  + +TG
Sbjct: 225 DKLAYMTG 232


>UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Comamonas testosteroni KF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Comamonas testosteroni
           KF-1
          Length = 263

 Score =  101 bits (242), Expect = 2e-20
 Identities = 61/191 (31%), Positives = 99/191 (51%), Gaps = 1/191 (0%)
 Frame = +3

Query: 159 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRL 335
           D   + LS+  D+T E+ IE +  K  D +G+ D+LVNNAG++     +E   +A +D++
Sbjct: 54  DNAQAALSLACDITDEAAIEAMAAKVKDTFGRCDILVNNAGVMAPVVPLEELPVAMWDKV 113

Query: 336 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515
           M+ N+R  +      V  +LE K          G R    +  Y  SKA V   T  +A+
Sbjct: 114 MSVNLRGSFLCAKYLVRMMLEQKRGAIVNLASIGARVPNDIGPYGPSKAGVLGLTHQMAV 173

Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695
           E  P+GVR N ++PG+I T +      +E+ +     R K    +GR G+P+++A  + F
Sbjct: 174 EWGPRGVRTNSISPGMIRTPMSEHFYQNEKLHQG---RIKVV-PVGRIGRPEDIADAMGF 229

Query: 696 LASDLASNITG 728
           + SD AS + G
Sbjct: 230 IVSDAASYMNG 240


>UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1;
           Methanobrevibacter smithii ATCC 35061|Rep: Short chain
           dehydrogenase - Methanobrevibacter smithii (strain PS /
           ATCC 35061 / DSM 861)
          Length = 269

 Score =  101 bits (242), Expect = 2e-20
 Identities = 65/216 (30%), Positives = 105/216 (48%), Gaps = 5/216 (2%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA++ + GR  E  Q V  +  K     S    D+T  + IEK+I  T + YGK+D+LVN
Sbjct: 32  GAKVVICGRREEKGQAVVDNITKEGGESSYHFFDITNTNSIEKLIDDTAEKYGKIDILVN 91

Query: 273 NAG--IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGI 440
           NA    ++ G I+  ++  +D +  +++R  +Y T   +P+L   E+ G           
Sbjct: 92  NAANVALKDGNIDELTIDMWDAIFESDLRGTFYATKCVIPYLQKNENGGSIINIGSMASC 151

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
               G  AY  +K+ VD FT+  AL+     +R NCV PG+I+T  +    + E     F
Sbjct: 152 GGDLGSTAYACAKSGVDMFTQYTALQYGKDNIRCNCVRPGLIVTP-ENEANVPEVLRNIF 210

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           L        + R G P+++     +LASD +  +TG
Sbjct: 211 LNNI----MVNRYGGPEDIGHMCVYLASDESEYVTG 242


>UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=2; Bacillus|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Bacillus halodurans
          Length = 252

 Score =  101 bits (241), Expect = 2e-20
 Identities = 62/211 (29%), Positives = 105/211 (49%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++++  R+   LQ+  +   +  + L+I AD+T +++ EK+  + ++ YG +D+LVNN
Sbjct: 31  GAKVAIVARDAHGLQEAKR---QLGNVLTIQADVTDKNEREKVFSQLLETYGTIDILVNN 87

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG    G I  T L+ ++   + N  S  + + LA+P +   +            R   G
Sbjct: 88  AGGSNGGLISETELSLFEEAFSLNYFSAVHFSQLALPVMKAKQSGAIINISSIFGRESGG 147

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
              YN +KA++  FT+ +A E+   G+RVN + PG IL          EE      +   
Sbjct: 148 KATYNSAKAAMISFTKSLADEVIRDGIRVNGIAPGSILHPTGNWQKRLEENREKMEQFID 207

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
           +    GR G  +E+A    FLAS+ AS + G
Sbjct: 208 QNIPAGRFGTVEEIANVAVFLASEKASWVVG 238


>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 254

 Score =  101 bits (241), Expect = 2e-20
 Identities = 72/241 (29%), Positives = 116/241 (48%), Gaps = 6/241 (2%)
 Frame = +3

Query: 24  GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLT 200
           GKVV                L   GA+++L   N ++L K  +    +     +IT ++T
Sbjct: 3   GKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNVT 62

Query: 201 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTML 377
            E D+E  +K+T+D +GK+DV  NNAG+      I     A ++++M+ NV  + +L + 
Sbjct: 63  VEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGV-FLGLK 121

Query: 378 AVPHLLESKGXXXXXXXXXGIR--SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551
            V   ++ +G                 G+++Y  SK +V   T+  ALE+A  G+RVN V
Sbjct: 122 HVMKQMKKQGYGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAALEVASDGIRVNAV 181

Query: 552 NPGVILTEL--QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
            P  I T++    +  L+  +     E  K+    GR G P+EVA  + FLASD AS + 
Sbjct: 182 APAAIDTQMLADIQNNLTPGEPEKSGEALKQGIPAGRFGAPEEVAQVVKFLASDDASFVN 241

Query: 726 G 728
           G
Sbjct: 242 G 242


>UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Geobacter metallireducens GS-15|Rep: Short-chain
           dehydrogenase/reductase SDR - Geobacter metallireducens
           (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 257

 Score =  101 bits (241), Expect = 2e-20
 Identities = 65/220 (29%), Positives = 114/220 (51%), Gaps = 6/220 (2%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
           ++ GA L L  RN+E  +  + +  K      ++  D+ ++ +++ ++  T++ +GK+D+
Sbjct: 32  AEAGASLVLCSRNLEQCEDAAANIRKLGVECDALRCDIGEQDEVKAVVAHTMNRFGKIDI 91

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXGI 440
           LVNNAGI   G +++T L ++D+L +TNVR  Y+ T   V P +    G         G+
Sbjct: 92  LVNNAGISWGGELQDTPLKKWDQLYSTNVRGNYFFTTEVVSPMIAGGGGNIINIVSIGGV 151

Query: 441 RSF-PGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
           RS  P V+   AY  +K ++   T+ ++   A   +RVN + PG+  TE+ +   L    
Sbjct: 152 RSTDPKVVTFPAYASTKGAIIALTKHLSRNWAKHNIRVNAIAPGIFPTEISKT--LMVGP 209

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             A +E       LGR G+ D+      FLA+D +  +TG
Sbjct: 210 QKAVMEAAV---PLGRLGEKDDFKGAALFLAADASRYVTG 246


>UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Herpetosiphon aurantiacus ATCC 23779
          Length = 257

 Score =  101 bits (241), Expect = 2e-20
 Identities = 67/243 (27%), Positives = 118/243 (48%), Gaps = 3/243 (1%)
 Frame = +3

Query: 9   TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSI 185
           T + +GKV                  ++ GA++ +  R +E+LQ V+   ++   T L++
Sbjct: 3   TFDLSGKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAM 62

Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIY 362
                K   ++ ++ +T+  +G++D++VNNA      G + N+  +Q+D+    NV+  +
Sbjct: 63  ACHTGKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYF 122

Query: 363 YLTMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
           +L   A   +  +  G         G++    +  Y+ISKA+V   T+ +A EL P  +R
Sbjct: 123 WLIQAAAEAMQAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIR 182

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN + PG+I T+       +E+     +  T     LGR G  DEVAA   +LASD A+ 
Sbjct: 183 VNALAPGLIKTKFSSALWDNEDLNQKIVAGT----PLGRIGTVDEVAAAALYLASDAAAF 238

Query: 720 ITG 728
            TG
Sbjct: 239 TTG 241


>UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Sinorhizobium medicae
           WSM419
          Length = 251

 Score =  101 bits (241), Expect = 2e-20
 Identities = 57/185 (30%), Positives = 99/185 (53%), Gaps = 1/185 (0%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           +++ AD++ ++++  + K   D +G LD +VNNAGI+ +G +E      +D +M+ N + 
Sbjct: 59  ITVCADVSSKAEVRAMAKAVGDAFGHLDAVVNNAGILISGDVEGLDEEHWDSVMDVNAKG 118

Query: 357 IYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533
            + +    +P +   + G         G    P    Y+ SKA+V  FTR +A E+   G
Sbjct: 119 TFLVVQAVLPMMKARRYGRIVNIASIGGKHGAPEQAHYSASKAAVMGFTRVLAQEVGVDG 178

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           +  NCV PG+ILT++  R  L +    A  +  ++  A+ R G P++V   +AF ASD A
Sbjct: 179 ITANCVCPGIILTDM-GRVNLDD---PAVKKSWQDKTAMRRIGDPEDVVGAVAFFASDDA 234

Query: 714 SNITG 728
           + +TG
Sbjct: 235 AFVTG 239


>UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           JLS)
          Length = 268

 Score =  101 bits (241), Expect = 2e-20
 Identities = 65/217 (29%), Positives = 103/217 (47%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L+  GA++++  R+ +     ++        L I  D+ + + +   + +T+   G + +
Sbjct: 32  LAAFGARVAIWERDADRCAVAAES----VGGLGIVTDVRESAAVTAALDRTVAELGTVTI 87

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXXG 437
           LVNNAG   +  +  TS   +D L   N+R +   T      ++ +   G         G
Sbjct: 88  LVNNAGGTFSSPLLETSENAWDALYKANLRHVLLCTQRVAQQMVAAGVGGSVITVTSIEG 147

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           +R+ PG  AY  +KA V  +T+  A ELAP G+RVN + P V++TE     GL       
Sbjct: 148 VRAAPGYAAYAAAKAGVVNYTQTAAFELAPHGIRVNALAPDVVVTE-----GLVALSPGG 202

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                 +   +GRPG  DE+A    FLASDLA  ITG
Sbjct: 203 LPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITG 239


>UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2;
           Pichia|Rep: (R)-2-octanol dehydrogenase - Pichia
           finlandica
          Length = 254

 Score =  101 bits (241), Expect = 2e-20
 Identities = 63/185 (34%), Positives = 96/185 (51%), Gaps = 3/185 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           + AD +KE D +K+I +T+  +G LD++  NAGI +      T    + +++  N+  ++
Sbjct: 65  VQADSSKEEDNKKLISETLATFGGLDIVCANAGIGKFAPTHETPFDVWKKVIAVNLNGVF 124

Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSF---PGVLAYNISKASVDQFTRCVALELAPKG 533
            L  LA+ + LE K           + SF   PG+  Y  +K  V   T+ +ALE A  G
Sbjct: 125 LLDKLAINYWLE-KSKPGVIVNMGSVHSFVAAPGLAHYGAAKGGVKLLTQTLALEYASHG 183

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           +RVN VNPG I T       L +E     L++    H +GR G+P+EVA  +AFL S  A
Sbjct: 184 IRVNSVNPGYISTP------LIDEVPKERLDKLVSLHPIGRLGRPEEVADAVAFLCSQEA 237

Query: 714 SNITG 728
           + I G
Sbjct: 238 TFING 242


>UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein;
           n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like
           protein - Streptomyces natalensis
          Length = 257

 Score =  100 bits (240), Expect = 3e-20
 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 9/220 (4%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA + L  R V+ L+ +  +  +  A    I  D+++E D+ + ++ T++ YG+LD+  N
Sbjct: 34  GAAVVLAARRVDRLRALVSEIRRTGAEAAYIATDVSQEEDVRRAVEFTVEKYGRLDLAFN 93

Query: 273 NAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXXGIR 443
           NAG+  +  ++       YD +M TNVR +++     +  +L +   G         G++
Sbjct: 94  NAGVGCDHESMHLMQQDTYDDVMGTNVRGVWHCLQHEISAMLHNGVGGSIVNNSSVAGLQ 153

Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-----QRRGGLSEEQ 608
           + P    Y  SK +V   T+  A E AP+G+RVN V PG   TE+      R  GL E+ 
Sbjct: 154 AIPAGAPYIASKHAVIGLTKAAAAEYAPQGIRVNSVAPGTTRTEIIAGWFDRNPGLEEQL 213

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           + A  +         R  +P+E+A  +A+L SD +S +TG
Sbjct: 214 HRATPQ--------ARTAEPEEIAQAVAWLCSDRSSFVTG 245


>UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Desulfuromonas acetoxidans
           DSM 684
          Length = 252

 Score =  100 bits (240), Expect = 3e-20
 Identities = 61/188 (32%), Positives = 96/188 (51%), Gaps = 2/188 (1%)
 Frame = +3

Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GT-IENTSLAQYDRLMNT 344
           S +    D++ E  ++ +       YG+LD+LVNNA + +  GT +E+ +L ++  L+N 
Sbjct: 51  SVIGKLVDVSDEKAVQLLFSWLEATYGRLDLLVNNAAVAKAHGTPLESLALEEWQHLLNV 110

Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           N+   +  +  A P L    G          ++S P   AY  SK  V   T  +AL L 
Sbjct: 111 NLTGPFLCSKYAAPLLRHPSGSIIHIASTRAVQSEPDSEAYAASKGGVVALTHAMALSLG 170

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
           P+ +RVNC++PG I     ++G     Q  +   +  E H +GR G+P ++AAT+ FLAS
Sbjct: 171 PQ-IRVNCISPGWIDVSALKKGAHGISQ--SLSRQDHEQHPVGRVGQPQDIAATVCFLAS 227

Query: 705 DLASNITG 728
             A  ITG
Sbjct: 228 AQAGFITG 235


>UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 252

 Score =  100 bits (240), Expect = 3e-20
 Identities = 61/209 (29%), Positives = 101/209 (48%), Gaps = 1/209 (0%)
 Frame = +3

Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
           + L G  +E+L   SK        L++  D+++ +D++  +   I  +GK+D+L NNAGI
Sbjct: 35  IDLDGGKLEHL--ASKITSSGGICLALRGDVSQSADVQNALNTAIGRFGKIDILFNNAGI 92

Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVL 461
           +  G I+ T+  Q+DR M  NV+S+Y      VPH  E   G          +R+     
Sbjct: 93  VPAGKIDVTTEEQWDRAMAINVKSMYLFCHAIVPHFKEHGGGVILNTASATALRAVVDRA 152

Query: 462 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 641
            Y  +KA+V   T+ +AL+     +RVNC+ PG + T        +    A   +     
Sbjct: 153 CYTATKAAVVGLTKSMALDYVRDNIRVNCLCPGTVDTPSLSERLAAFPDPAEAKKNFIAR 212

Query: 642 HALGRPGKPDEVAATIAFLASDLASNITG 728
             +GR G  +E+A    +L SD ++ +TG
Sbjct: 213 QPMGRFGTAEEIALAALYLVSDESAFVTG 241


>UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase;
           n=1; Burkholderia xenovorans LB400|Rep: Putative
           short-chain type dehydrogenase - Burkholderia xenovorans
           (strain LB400)
          Length = 252

 Score =  100 bits (240), Expect = 3e-20
 Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 6/187 (3%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           +  D+T E+ +  +I + ++  G LD L  NAG+  +G I     A +D L   N R+ +
Sbjct: 58  VQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRSGAIAGFEQANWDALFAVNARAHF 117

Query: 363 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
           +    A+PHL  S KG         G R  PG++AY+ SK +V  FT  +ALELAP  +R
Sbjct: 118 FGAKHAIPHLQRSGKGSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALALELAPDNIR 177

Query: 540 VNCVNPGVILTELQR-----RGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
           VN + PG + T   +      GG   +Q     ++      LGR     E+A    +LAS
Sbjct: 178 VNAICPGWVDTAFNQPAIDFMGGADAQQ-----KKIASLVPLGRQASATEIAPLFVYLAS 232

Query: 705 DLASNIT 725
           D ++ +T
Sbjct: 233 DESAYVT 239


>UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Roseovarius sp. HTCC2601
          Length = 255

 Score =  100 bits (240), Expect = 3e-20
 Identities = 60/186 (32%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           +++  D++ E  ++ +  + I  +G LD +VN AG+   G I +T    +D  MN N+  
Sbjct: 58  VAVGVDVSDEDKVDAMTAEGIAKFGGLDGVVNCAGVRGVGNILDTDHGVWDLNMNVNIEG 117

Query: 357 IYYLTMLAVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
            +  +     +  E    G         G+ + P  L+Y  SK  V   TR VA+E+AP 
Sbjct: 118 SFNTSQAFCRYAREHNRPGSIVNISSQAGVEAVPNRLSYVTSKHGVVGLTRGVAIEMAPH 177

Query: 531 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 710
           G+R N + PG+I T +        E     LE+ ++ H +GR G+P+E+AA I+FL SD 
Sbjct: 178 GIRCNGIAPGMIATAMTAGMRADPEN----LEKIRKAHPIGREGQPEEIAAVISFLLSDD 233

Query: 711 ASNITG 728
           AS +TG
Sbjct: 234 ASYVTG 239


>UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Bacteroidetes|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Flavobacterium
           johnsoniae UW101
          Length = 247

 Score =  100 bits (240), Expect = 3e-20
 Identities = 69/213 (32%), Positives = 104/213 (48%)
 Frame = +3

Query: 90  KLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           K GA + +TGRN ENL+K + + +      +I +D    SD+  + K   ++   LDVL 
Sbjct: 27  KAGANVWITGRNSENLEKAANEINS-QKLKTIVSDTANLSDLSLLEKAFAENNAPLDVLF 85

Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449
            NAGI    +IE+ + A +D   NTNV+  ++     +PHL E               S 
Sbjct: 86  LNAGIARFTSIEDVTEADFDAQFNTNVKGHFFTLQKLLPHLAEGSS-VIFTSSTVATASN 144

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
            G   Y+ +K ++++  +  A ELA + +RVN V+PG + T      GL         E 
Sbjct: 145 LGSSIYSATKGALNKIAQIAANELAGRKIRVNIVSPGPVSTP-----GLHNAVPEEAKEY 199

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                A+ R G   E+A T+ FLAS+ AS ITG
Sbjct: 200 LAGATAMQRLGDSSEIAKTVLFLASENASFITG 232


>UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Novosphingobium aromaticivorans DSM
           12444|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Novosphingobium aromaticivorans (strain DSM
           12444)
          Length = 253

 Score =  100 bits (240), Expect = 3e-20
 Identities = 62/174 (35%), Positives = 88/174 (50%), Gaps = 5/174 (2%)
 Frame = +3

Query: 222 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES 401
           ++ + ++  G +D+L+N AGI+  G  E TS   + R M+ N+   ++L   ++PHL  S
Sbjct: 69  LVTEAVEVLGGIDILLNVAGIMTWGRFEETSPQAWQRTMDINLSGPFFLIQASIPHLKAS 128

Query: 402 KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 581
           KG         G+    G  AY +SKA V   T+  ALE A  GVR N V PG + T + 
Sbjct: 129 KGNVVSVASAGGLHPVYGTSAYGVSKAGVIAITQSAALEFARFGVRANAVAPGGVATPMH 188

Query: 582 RR----GGLSEEQYAAFLERTKETHALGRPG-KPDEVAATIAFLASDLASNITG 728
            +    GG+    +A    R        RP   P+EVAA IA+LASD A   TG
Sbjct: 189 EKSSAGGGVDPAIFAEAAGRNM-PKLTDRPACTPEEVAAAIAYLASDEARYATG 241


>UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 300

 Score =  100 bits (240), Expect = 3e-20
 Identities = 63/188 (33%), Positives = 106/188 (56%), Gaps = 4/188 (2%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVR 353
           L+I AD T ESD+E  +KKT+  +G+LD  + NAG   ++ ++ +T+   ++ +M TN R
Sbjct: 106 LTIAADATNESDVEACVKKTVQRFGRLDCALLNAGERDDSKSLFDTTAEDFESIMTTNAR 165

Query: 354 SIYYLTMLAVPHLLESK---GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           S  +L +  V  +L  +   G         G+R FPG+++Y+ SK ++       A EL 
Sbjct: 166 SA-FLGLKHVAKVLRDQGQGGSIILRSSIAGLRGFPGLISYSSSKFALRGIALTAAEELG 224

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704
              +RVN ++  +I +    + G ++E+    L+  K   ALGR G+PD+VA  +AFLAS
Sbjct: 225 EFDIRVNTIHTSIIDSGPGFKEGWTQER----LDELKGETALGRFGRPDDVANVVAFLAS 280

Query: 705 DLASNITG 728
           + +  +TG
Sbjct: 281 EDSKFMTG 288


>UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Syntrophomonas wolfei subsp. wolfei str.
           Goettingen|Rep: Short-chain dehydrogenase/reductase SDR
           - Syntrophomonas wolfei subsp. wolfei (strain
           Goettingen)
          Length = 253

 Score =  100 bits (239), Expect = 4e-20
 Identities = 67/214 (31%), Positives = 113/214 (52%), Gaps = 3/214 (1%)
 Frame = +3

Query: 96  GAQLSLTGRN--VENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           GA + +  R+  +E L+   +  +K A  L+I ADL++E+++E++  +     G ++ LV
Sbjct: 34  GASVIINYRSSELEALRLARELREKGAGVLAIRADLSRENEVERMFTRIEAEMGNVNALV 93

Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRS 446
            NAGI + G +   S  Q+DR+M+TN++  +     A+P+++  + G         GI  
Sbjct: 94  YNAGISQRGLLIECSEEQWDRVMDTNLKGAFLCCRRALPYMIRERFGRIINIASVLGITG 153

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626
                 Y+ +K  +   TR +A E+ P G+ VN + PG I T++ R   L E++ A   +
Sbjct: 154 ASYESIYSSAKGGLIALTRSLAQEVGPSGITVNAIAPGPIFTDMLRE-ELDEDEMA---D 209

Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            T+E   +GR G P +VAA   FL    AS I G
Sbjct: 210 LTREI-PVGRLGCPKDVAAACVFLLGREASFING 242


>UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Glucose-1-dehydrogenase -
           Lentisphaera araneosa HTCC2155
          Length = 264

 Score =  100 bits (239), Expect = 4e-20
 Identities = 52/189 (27%), Positives = 100/189 (52%), Gaps = 2/189 (1%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           ++ L++  D+  +   + +I K I+ +G++D +VNNAGI        T+   +D+++NTN
Sbjct: 51  SNALAVACDVCSDEAQQNVIDKAIEKWGRVDCIVNNAGINFAKPFLETTKQDWDKVLNTN 110

Query: 348 VRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 521
           +R++++       + +  ++KG            + PG   Y  +K  +    +C   EL
Sbjct: 111 LRAVFFFMQKLCKYWIDNQTKGSIVNISSVHNQATLPGAGPYAATKNGLLGIMKCAVNEL 170

Query: 522 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701
           + KG+RVN V+PG+  T + +    +       L+  K+   +GRP +P+E+  T++FL 
Sbjct: 171 SSKGIRVNTVSPGLCNTNIWQDIIEAAPNEKECLDYWKQQIPIGRPSEPEEIGYTVSFLL 230

Query: 702 SDLASNITG 728
           SD +S+ TG
Sbjct: 231 SDRSSSTTG 239


>UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Roseiflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Roseiflexus sp. RS-1
          Length = 264

 Score =  100 bits (239), Expect = 4e-20
 Identities = 62/184 (33%), Positives = 100/184 (54%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           ++I  DL++ +D E+++  T++ +G+LD+LVNNAGI  +  + + +  ++D L+NTN+RS
Sbjct: 80  IAIPGDLSRVADCERVVDATLEQWGRLDLLVNNAGIWGSTPVGSVTEERWDELLNTNLRS 139

Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           ++++   A   L  S G           R +     Y ISK  V   TR +A +LAP+ +
Sbjct: 140 MFFVAQRAADALRASHGVIINIADVGVERPWRNHTPYLISKGGVVTLTRALAKDLAPE-I 198

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
           RVN + PG +L        L ++  A   ER   T  L R G P+++A  + FLA   A 
Sbjct: 199 RVNAIAPGPVL--------LPDDWGAEQAERVARTTLLRRIGSPEDIADAVIFLAQ--AG 248

Query: 717 NITG 728
            ITG
Sbjct: 249 YITG 252


>UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=30; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidovorax sp. (strain
           JS42)
          Length = 257

 Score =  100 bits (239), Expect = 4e-20
 Identities = 61/216 (28%), Positives = 108/216 (50%), Gaps = 5/216 (2%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           G  + + G   E  ++  K+        ++TA+LTK+ D+  ++K   + +  +D+LVN 
Sbjct: 31  GGNVVIVGNRPEKTEEARKELAALGQVSALTANLTKDEDVAALLKAIDEQHPDIDLLVNA 90

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG+         S A YD+ M  N ++ +++T   V   L +KG          + +   
Sbjct: 91  AGVFFPKPFLEHSDADYDQYMKLN-KAFFFITQ-KVAGNLAAKGKPGAIVNIGSMWAKQA 148

Query: 456 VL-----AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
           +      AY+++KA +   T+ +A+ELAPK +RVN V+P V+ T +   G + + +    
Sbjct: 149 IAATPSSAYSMAKAGLHSLTQHLAMELAPKHIRVNAVSPAVVETPIY-EGFIPKAEVHGA 207

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           ++     H +GR G P +VA  + FL SD A  +TG
Sbjct: 208 MQGFNSFHPIGRVGTPQDVAEAVVFLLSDKAGWVTG 243


>UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular
           organisms|Rep: Glucose 1-dehydrogenase - Bacillus
           subtilis
          Length = 261

 Score =  100 bits (239), Expect = 4e-20
 Identities = 57/184 (30%), Positives = 95/184 (51%), Gaps = 2/184 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           +  D+TKE D++ I++  I  +G LD+++NNAG+          L  +D+++ TN+   +
Sbjct: 62  VQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGAF 121

Query: 363 YLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
             +  A+ + +E+  KG          +  +P  + Y  SK  +   T  +ALE APKG+
Sbjct: 122 LGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGI 181

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
           RVN + PG I T +        +Q A      +    +G  G+P+E+AA  A+LAS  AS
Sbjct: 182 RVNNIGPGAINTPINAEKFADPKQKA----DVESMIPMGYIGEPEEIAAVAAWLASKEAS 237

Query: 717 NITG 728
            +TG
Sbjct: 238 YVTG 241


>UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Bacillus halodurans
          Length = 246

 Score =   99 bits (238), Expect = 6e-20
 Identities = 67/218 (30%), Positives = 110/218 (50%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLT-GRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 257
           L++ GA + +    N E  +KV  +  +     ++I AD+     ++ ++K+TID +G +
Sbjct: 24  LARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQADVADSESVQAMVKETIDTFGAV 83

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXX 434
           D+LVNNAGI             +D +++TN++ +++ +     P + +  G         
Sbjct: 84  DILVNNAGITRDNLFMRMKEEDWDAVIDTNLKGVFHCSKAVTRPMMKQRFGRIINVSSVV 143

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G     G   Y  +KA V   T+ +A ELA + + VN V PG I T++   G L E+  A
Sbjct: 144 GAIGNAGQANYVAAKAGVIGLTKTLARELANRNITVNAVAPGFIETDM--TGELPEDVKA 201

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
             L +      L R G+P+EVA  + FLASD AS +TG
Sbjct: 202 QMLGQI----PLARLGQPEEVAKAVRFLASDDASYLTG 235


>UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6;
           Pseudomonas aeruginosa|Rep: Probable short-chain
           dehydrogenase - Pseudomonas aeruginosa
          Length = 252

 Score =   99 bits (238), Expect = 6e-20
 Identities = 58/185 (31%), Positives = 97/185 (52%), Gaps = 5/185 (2%)
 Frame = +3

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           ADL    +   ++ K +   G+LD LVN AG+   G +EN +   +D ++  N+++ +Y+
Sbjct: 55  ADLRSADNCHTLMSKILARTGRLDALVNAAGVWREGPVENFTEEDFDLVLGVNLKASFYM 114

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
              A+P+L E++G         G +++ G  AY  SKA++   ++ +ALELA +GVRVN 
Sbjct: 115 CQAAIPYLKENQGSIVNISSDSGRQAYRGSAAYCASKAALTMLSKTLALELAEQGVRVNA 174

Query: 549 VNPGVILT-----ELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           V+P  I T     + +R G  + + Y   L +        R  +P+EVA  + +L    A
Sbjct: 175 VSPADIATPMLDYQAERYGMGNPDGYKRALLKDYPQGKAARFIRPEEVAELVWYLCGPQA 234

Query: 714 SNITG 728
             ITG
Sbjct: 235 EAITG 239


>UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Rep:
           Blr3449 protein - Bradyrhizobium japonicum
          Length = 256

 Score =   99 bits (238), Expect = 6e-20
 Identities = 62/213 (29%), Positives = 108/213 (50%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA++ +T    +    V+++  D     +  + D+T      ++ ++  +  G  DV+VN
Sbjct: 37  GARVVVTDLGQDRADSVAREIRDGGKEAIGCSLDVTDALACGEVARRVDEELGLADVVVN 96

Query: 273 NAGIIETGTIENTSLAQ-YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449
           NAGII    I++    + + ++ + NV   + +    +P L +S G            S 
Sbjct: 97  NAGIIIREPIDSPRAHENWRQVFDVNVNGTFNVVHAFIPALRKSPGTIINVASVAAFGSM 156

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
            G + Y+ SK +V  FT+ +A +LAP G+RVN V PG+I TE+      +  + +  + R
Sbjct: 157 GGTVGYSSSKGAVRLFTQALARDLAPDGIRVNAVAPGIIATEMSESTRGNPARLSGLMAR 216

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           T     L R G+P+E+AA + FLAS +AS + G
Sbjct: 217 T----PLKRVGQPEEIAAPVIFLASAMASYVNG 245


>UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=14; Clostridia|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium
           tetani
          Length = 249

 Score =   99 bits (238), Expect = 6e-20
 Identities = 55/183 (30%), Positives = 95/183 (51%), Gaps = 1/183 (0%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           I  D++   D + +I+K I  +GK+D+L+NNAGI + G   +     +D ++NTN++ ++
Sbjct: 63  IKCDVSSYEDTKLMIEKIIRDFGKIDILINNAGISKIGLFIDMEEEDWDNIINTNLKGVF 122

Query: 363 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
             +   +P+++ E  G         G       + Y+ SK  VD FT+ +A E+ P  +R
Sbjct: 123 NCSRNVLPYMIGEKNGVIINISSMWGSVGASCEVIYSASKGGVDSFTKALAKEVGPSNIR 182

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           VN ++PGVI T +       E+      +  K+   L R G+ +++   + FL SD A  
Sbjct: 183 VNAISPGVINTSMNEWMSCEEK------DSLKDEIPLCRFGECEDIGKAVVFLCSDNAKY 236

Query: 720 ITG 728
           ITG
Sbjct: 237 ITG 239


>UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=21;
           Bacteria|Rep: Short-chain dehydrogenase/reductase -
           Klebsiella pneumoniae
          Length = 302

 Score =   99 bits (238), Expect = 6e-20
 Identities = 61/184 (33%), Positives = 98/184 (53%), Gaps = 1/184 (0%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRS 356
           +I  D+  E+    ++K+ +D  G LD+LVNNAG  +   +IE+ +  ++D    TNV +
Sbjct: 112 AIPGDIRDETFCNHLVKQAVDALGGLDILVNNAGRQQFCESIEDLTTEEFDATFKTNVYA 171

Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           ++++T  A+PH                      +L Y  +KA++  FT+ +A +LAPKG+
Sbjct: 172 MFWITKAAIPHFSRDS-VIINTSSVQAYEPSEILLDYAQTKAAIVAFTKSLAKQLAPKGI 230

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
           RVN V PG   T LQ  GG  +E+    +E+      LGRPG+P E+A     LA++  S
Sbjct: 231 RVNAVAPGPYWTVLQCCGGQPQEK----IEKFGANAPLGRPGQPVEIAPLYVTLAAEENS 286

Query: 717 NITG 728
             +G
Sbjct: 287 YTSG 290


>UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 -
           Clostridium kluyveri DSM 555
          Length = 250

 Score =   99 bits (238), Expect = 6e-20
 Identities = 59/219 (26%), Positives = 120/219 (54%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVEN--LQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKL 257
           ++K GA++ +   N +   L+ V +  D   +++++ AD++K ++++K+I   ++++G++
Sbjct: 25  MAKEGARIIVNYNNSKKKALEVVKEIEDIKGTSIAVKADVSKRNEVKKMIDIAVENFGEI 84

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
            +LVNNAGI++    E+ +  ++D++   N++  +  T   +P++L++           G
Sbjct: 85  HILVNNAGILQQKPFESITDDEWDKMFQVNMKGAFICTQECIPYMLKNNFGRIINISSIG 144

Query: 438 IRSFPGVLA--YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
              + G LA  Y+ +KA +    R +A   +  G+  NC+ PG++LTE+  +   +E   
Sbjct: 145 -GQWGGNLAVHYSATKAGIISLARSLARIYSKDGINTNCIAPGLVLTEMSAKEMATE--- 200

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            A  E+ K    + RP  P+E+     FLAS+  S ITG
Sbjct: 201 -AGKEKLKGI-PINRPAAPEEIGRIAVFLASEDGSYITG 237


>UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Novosphingobium aromaticivorans DSM 12444|Rep:
           Short-chain dehydrogenase/reductase SDR -
           Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 246

 Score =   99 bits (238), Expect = 6e-20
 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 1/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA++++  +NV  L++ +      AS   I   D    +   K+++  +     LDVL N
Sbjct: 29  GARVTIGDKNVAGLEETAA---MMASAPVIQPFDAVDNASCRKLVE--VGARNGLDVLCN 83

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452
            +G+++ G  E+ SL  +D +M  N  S++ L   A+PHL+ESKG          ++   
Sbjct: 84  ISGVLKWGRSEDFSLEDFDLVMRVNTHSVFTLCQAALPHLVESKGNIVNTASAAALQGIA 143

Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632
             +AY  SK +V   T+ +A+E A +GVRVN + PG + T + ++  + E    A + R 
Sbjct: 144 YTVAYVASKHAVAGMTKSLAVEFASRGVRVNAICPGDVKTPMTQQTAVPENVDWALVMR- 202

Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728
                L    +P+++A   AFLAS+ A  ITG
Sbjct: 203 NAPKLLDGSCEPEDIAELFAFLASERARKITG 234


>UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=4; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 254

 Score =   99 bits (238), Expect = 6e-20
 Identities = 68/214 (31%), Positives = 111/214 (51%), Gaps = 3/214 (1%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA++ LT R++   +KV++          ++  D+T E+  +++        GKLDVLVN
Sbjct: 32  GAKVWLTDRDLAGAEKVAEGIRAAGGQARALLHDVTNEAQWDEVFAAIEAEDGKLDVLVN 91

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRS 446
           NAGI     I   + A ++   + N+ S++  T  AV  + ++  KG         G+  
Sbjct: 92  NAGIAVLRPIAEMTTADWNLQNSVNLDSVFQGTKRAVVLMRKTGTKGSIINISSVAGLIG 151

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626
            P   AY  +K  V  F++ +A+E A  G+RVN V+PG+ILT +Q   G+++E  AA  +
Sbjct: 152 VPACGAYAAAKGGVRLFSKTIAVETAKDGIRVNSVHPGMILTNIQ---GVAQEDNAANYD 208

Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            T     +G  G P ++A    FLASD +  +TG
Sbjct: 209 ATLALVPMGYMGDPLDIANMNLFLASDESRYVTG 242


>UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=3; Trichocomaceae|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Aspergillus fumigatus (Sartorya fumigata)
          Length = 256

 Score =   99 bits (238), Expect = 6e-20
 Identities = 72/249 (28%), Positives = 114/249 (45%), Gaps = 10/249 (4%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS------ 173
           M+  GK+                 L+K GA L+L   +  + Q +++ CD+  S      
Sbjct: 1   MSLRGKIAIVTGASRGIGAGIALDLAKQGANLTLIYTSASSDQAINQLCDQIHSLNNGST 60

Query: 174 TLSITADLTKESDIEKIIKKTIDHY----GKLDVLVNNAGIIETGTIENTSLAQYDRLMN 341
            + + ADL       +I+  T D +     K+D+LVNNAG+     + +T+      + +
Sbjct: 61  AIKVQADLRHSDAPAQILAATFDAFPNANNKIDILVNNAGVSLCKNLADTTDHDISSVFD 120

Query: 342 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 521
            NV  +  +T   +PHL  + G           R  PG   Y+ SKA+V+ FTR +A EL
Sbjct: 121 INVYGLISMTRAVIPHL-RAPGRIINLSSVAARRGSPGFSVYSASKAAVEGFTRSLACEL 179

Query: 522 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701
            P G  VN V PG + +++ RR  + E+  A   E T   H   R   P++ A  + FLA
Sbjct: 180 GPVGCTVNAVQPGAVESDMLRR-EVPEQLIAYIQENTPLGH---RIALPEDTARVVTFLA 235

Query: 702 SDLASNITG 728
            + A  +TG
Sbjct: 236 GEGAGWVTG 244


>UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reductase;
           n=5; Pezizomycotina|Rep: 1,3,6,8-tetrahydroxynaphthalene
           reductase - Neosartorya fischeri (strain ATCC 1020 / DSM
           3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
           1020 / DSM 3700 / NRRL 181))
          Length = 276

 Score =   99 bits (238), Expect = 6e-20
 Identities = 62/224 (27%), Positives = 115/224 (51%), Gaps = 9/224 (4%)
 Frame = +3

Query: 84  LSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKL 257
           L++ GA +++  G + ++ Q+V +      S  ++I ADLT   +IE +IK+ + H+G+L
Sbjct: 32  LARRGASVAINYGHSAKSAQEVVEAIQAIGSQAVAIKADLTCVPNIESLIKQVVSHFGRL 91

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
           D++V+N+G+ +   +E T+L  ++ + N N R+  ++   A  H+              G
Sbjct: 92  DIVVSNSGMEKFKPLEETTLEDFNEVFNLNTRAQMFVARYAYDHIQPGGRVILMSSIAAG 151

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE---Q 608
           +   PG   Y  SKA+++ FTRC+A +   KG  VN + P  + +++ R           
Sbjct: 152 L-GVPGHALYAGSKAAIEGFTRCLAADFGRKGCTVNAIAPAGVKSDMWRENAWRYAPGCD 210

Query: 609 YAAFLERTKETHALGRP----GKPDEVAATIAFLASDLASNITG 728
            ++ LE  +   A G P    G P+++   ++FLAS  A  + G
Sbjct: 211 KSSSLEEIEAALAGGSPLKRCGVPEDIGKVVSFLASPDAEWVNG 254


>UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=26; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 248

 Score =   99 bits (238), Expect = 6e-20
 Identities = 62/212 (29%), Positives = 108/212 (50%), Gaps = 2/212 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA + + G N E  Q V +        +S    D++    ++  ++K +D + K+D+LVN
Sbjct: 31  GADVEIWGLNEERGQAVIESLTGLGGEVSFARVDVSHNGGVKDCVQKFLDKHNKIDILVN 90

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 449
           NAGI     +   S   +  +++TN+ S+YY     + H+++++ G              
Sbjct: 91  NAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSSVIRHMIKARSGSIINVASIVAKIGS 150

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
            G   Y  +KA +  FT+ +A E+A + +RVNC+ PG I T++     L++   A +L  
Sbjct: 151 AGQTNYAAAKAGIIAFTKSLAKEVAARNIRVNCLAPGFIETDM--TSVLNDNLKAEWL-- 206

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNIT 725
             ++  LGR G P++VA    FLAS L+S +T
Sbjct: 207 --KSIPLGRAGTPEDVARVALFLASQLSSYMT 236


>UniRef50_Q98H65 Cluster: Short chain dehydrogenase or
           3-ketoacyl-CoA reductase; n=2; Alphaproteobacteria|Rep:
           Short chain dehydrogenase or 3-ketoacyl-CoA reductase -
           Rhizobium loti (Mesorhizobium loti)
          Length = 248

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 62/184 (33%), Positives = 92/184 (50%), Gaps = 1/184 (0%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
           ++  D+ + +++EK+ +     +GK  +L+NNA     GT E  S A Y RL +TNV   
Sbjct: 60  AVQGDVAEAAEVEKMFEAAEIAFGKPSILINNAATASFGTFEEASEADYRRLFDTNVLGT 119

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
              T  A+ H  E+ G              P    Y+ SKA++D  T  ++ EL  + +R
Sbjct: 120 ILTTKAAMRHFPETGGSIVNIGTISSWNPVPNTSLYSASKAAIDTLTLSLSRELGARNIR 179

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALG-RPGKPDEVAATIAFLASDLAS 716
           VN V PG   TE+    G+    +   L        LG R GKPD++A T+AFLASD A+
Sbjct: 180 VNIVAPGYTHTEMTE--GMVGTDFGNMLIAGV---PLGQRFGKPDDIAPTVAFLASDEAA 234

Query: 717 NITG 728
            +TG
Sbjct: 235 WLTG 238


>UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1;
           Mesorhizobium loti|Rep: Probable short-chain
           dehydrogenase - Rhizobium loti (Mesorhizobium loti)
          Length = 261

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 62/192 (32%), Positives = 92/192 (47%), Gaps = 5/192 (2%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           A  L  T D++    +   +   +  +G +DV+VN+A +   GT   T    ++R M+ N
Sbjct: 54  ADALVQTVDVSISDQVRDAVVAGVAKFGGIDVIVNSAAVHPYGTATTTDWETWNRAMSVN 113

Query: 348 VRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           V SIY      +P +++   G         G      V AY  +K ++   TR +AL+ A
Sbjct: 114 VGSIYLTAHFGIPEMIKRGGGAIVNVASVQGFACQQNVAAYATTKGAIHTLTRSLALDYA 173

Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE----RTKETHALGRPGKPDEVAATIA 692
             G+RVN V+PG I T +  +    +    A +E    R    H LGR G+P+EVA  IA
Sbjct: 174 AAGIRVNSVSPGSIRTPILEKAARGDHGSDADVEEAYKRFGAAHPLGRIGEPEEVAEFIA 233

Query: 693 FLASDLASNITG 728
           FL S  AS  TG
Sbjct: 234 FLCSSKASFCTG 245


>UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1;
           Thermobifida fusca YX|Rep: Short chain dehydrogenase -
           Thermobifida fusca (strain YX)
          Length = 262

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 6/189 (3%)
 Frame = +3

Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-----TGTIENTSLAQYDRLMNT 344
           ++  DL   + + +++++ +   G LD LVNNAG+++     T T+E      +DR+   
Sbjct: 58  AVAVDLADSAQVRRMVEEAVAAGGGLDTLVNNAGVLDSAFTDTPTVEELPEEAWDRVYAV 117

Query: 345 NVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 521
           NV++++  T  A PHL  S +G            +  G  AY  SK +V Q TR +A+ L
Sbjct: 118 NVKAVWLATKFAAPHLRASERGPSVVNAASVAGMTGYGSPAYASSKGAVIQLTRSMAIAL 177

Query: 522 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701
           +P+ VR N   PG I T + R    + E   A L      H + R G+P EVA  + FLA
Sbjct: 178 SPQ-VRCNAYCPGSIETPMSRAHLEASEDREARLRSMIGAHLIPRFGRPSEVAKVVCFLA 236

Query: 702 SDLASNITG 728
           SD AS +TG
Sbjct: 237 SDDASFVTG 245


>UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Carboxydothermus
           hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Carboxydothermus
           hydrogenoformans (strain Z-2901 / DSM 6008)
          Length = 249

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 65/217 (29%), Positives = 110/217 (50%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           +++ GA++ +  RN E  +K +    +K     SI  D+ K +DI+K++ +    YG++D
Sbjct: 26  IAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDVGKVADIKKLVSEVYGRYGRID 85

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437
           +LVN AG+     IE  +   ++ +++ N++  ++  + A  H++  K G          
Sbjct: 86  ILVNCAGVNVRKPIEEYTEEDWNYMVDINLKGTFFACIEAGKHMIAQKEGVIVNLASIQA 145

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
               P    Y  +K  V Q T+ +A+E A   +RVN V+P  I TE+  +  + ++ Y  
Sbjct: 146 EEVLPERGIYATTKGGVKQLTKALAVEWAKYNIRVNAVSPAFIKTEMVEK--VLQDPYWG 203

Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            L   K    + RPG P+EVA  I FL S  AS ITG
Sbjct: 204 NLIINKT--PMRRPGTPEEVAEAILFLVSPKASYITG 238


>UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain
           dehydrogenase; n=1; Saccharopolyspora spinosa|Rep:
           Putative oxidoreductase, short chain dehydrogenase -
           Saccharopolyspora spinosa
          Length = 240

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 60/183 (32%), Positives = 88/183 (48%), Gaps = 1/183 (0%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           I  D+     +  ++ + +   G LD +VN AGI  +G +E      +D  +  NV+S +
Sbjct: 47  IKCDVADSGSVAAMVDEAVTGLGGLDAVVNVAGIQRSGAVEVLDETDWDDQLRVNVKSCF 106

Query: 363 YLTMLAVPHLLESKGXXXXXXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
             +  AVPHL  + G          G++ F G+ AY+ SK +V  FTR +A+E+A   +R
Sbjct: 107 LTSKYAVPHLRAAGGGSITTTASLAGLKGFAGMTAYSASKGAVIAFTRTLAVEVAADNIR 166

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
            NC+ PG + T         E    A L   K    L R   P E+A   AFL SD AS 
Sbjct: 167 ANCLCPGWVDTPFNDPVITFEGGREAHLANVKANVPLSREAAPPELAKWHAFLVSDAASY 226

Query: 720 ITG 728
           +TG
Sbjct: 227 MTG 229


>UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1;
           Frankia alni ACN14a|Rep: Putative Short chain
           dehydrogenase - Frankia alni (strain ACN14a)
          Length = 263

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 67/218 (30%), Positives = 103/218 (47%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLD 260
           L   GA++++  R    L  V+   D  A+  ++I+ADLT E D+ ++  + +D  G +D
Sbjct: 30  LDAAGARVAVVARGGAGLAAVA---DGLANKPVTISADLTVEDDVRRVADQALDELGDVD 86

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           +LVNNAG+      E  +    D  +N N+R++  LT    P LL  +G           
Sbjct: 87  ILVNNAGLGWHQPPEAITAKPLDLQLNLNLRNVILLTSWLAPSLLRRRGCVVTMSSAAAY 146

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYA 614
                   Y  +K  ++  T+ +A     +GVRVN V PG + T++ +     L EE Y 
Sbjct: 147 GGDVEQAVYAATKGGLNTLTQNLATAWGDRGVRVNAVAPGFVDTDIWQPLIAALGEEGYQ 206

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            F   T     L R    DE+A  + FL SD AS +TG
Sbjct: 207 RFRRATAAGIPLRRWASADEIATVVLFLCSDAASYLTG 244


>UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobacter
           sp. NAP1|Rep: Glucose dehydrogenase - Erythrobacter sp.
           NAP1
          Length = 255

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 64/210 (30%), Positives = 95/210 (45%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ +TGR  + +     +    A      AD T  SD++ +     D +G++D+L  N
Sbjct: 36  GAEVIITGRKQKGIDAALAELG--AGAHGFVADSTSISDLQALADFAKDTFGEVDILFAN 93

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG      I+      Y R  + NV+  ++     +P +L               +  PG
Sbjct: 94  AGNGMFAPIDQVDEELYARQFDLNVKGAFFTVQAFLP-VLSGNSSVIITSSAVHAKGAPG 152

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
              Y  SKA+V  F R +A EL  +GVRVN ++PG++ T          E Y  F     
Sbjct: 153 GTLYFASKAAVRSFARTMAAELGGRGVRVNTLSPGIVPTNFFENSNAPTELYHDFEAMAG 212

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNIT 725
           +   LGR GKP E+A    FLASD AS +T
Sbjct: 213 QGAPLGRAGKPVEIAEVAVFLASDEASFVT 242


>UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=1; Mycobacterium smegmatis str. MC2
           155|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 236

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 60/184 (32%), Positives = 92/184 (50%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           L++ AD+T E D+ K+    +  YG++D LV  AG++E   + +  LA +++ +  N+  
Sbjct: 47  LTVPADVTSEHDVAKLTSAAVIEYGRIDALVTLAGVMEQTLLPDLDLATWNQTIAVNLTG 106

Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
            +     A   L+++ G         G        AY  SKA V   TR +A EL P  V
Sbjct: 107 TFLCAKAAADELMKTGGTIVTIGSQIGYVGGINCAAYTASKAGVAGLTRALARELGPT-V 165

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
           RVNCV PG I T +       E     ++E+   +  +GR G PDEVA  +++L  D AS
Sbjct: 166 RVNCVAPGPIETPMTAVHATPE-----WVEQKTRSLVMGRFGTPDEVATAVSWLVGDEAS 220

Query: 717 NITG 728
            +TG
Sbjct: 221 FVTG 224


>UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
           Short-chain dehydrogenase/reductase SDR - Halorubrum
           lacusprofundi ATCC 49239
          Length = 263

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 67/219 (30%), Positives = 107/219 (48%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 260
           ++  GA +  + R    ++ V+ +   F      ITAD+T + D+E ++++ +D +G LD
Sbjct: 38  MAAAGATVVPSARTAAEVEAVADEARDFGVEARGITADVTDDDDVEALVEEIVDAFGSLD 97

Query: 261 VLVNNAGIIETGTIENTSLAQ---YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 431
           +LVNNAG      + + +  +    D +++ N+R  +     A PHL E+ G        
Sbjct: 98  ILVNNAGFNPGDALGDPAEIESDAVDSVLDVNLRGAFRTLRAAGPHLKEAGGSVVNVASV 157

Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
            G    P    Y  SK  +   T+  A++ AP+ VRVN V PG + T+L      +E   
Sbjct: 158 AGEVGLPKQHPYVASKHGLVGLTKSAAMDWAPE-VRVNAVAPGYVATDLTETLQENERLR 216

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            + L+RT     L R   P E+A    FLASD AS +TG
Sbjct: 217 QSILDRT----PLDRFADPMEIAGPAVFLASDAASFVTG 251


>UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=9; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex
           aeolicus
          Length = 248

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 67/218 (30%), Positives = 112/218 (51%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKD-CDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 257
           L+  G+ + +TG + E  + V+++  +K+      +  +L  E  I K  ++  +    +
Sbjct: 27  LASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMNLLSEESINKAFEEIYNLVDGI 86

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434
           D+LVNNAGI         SL  ++ ++  N+   + +T  ++  +++ + G         
Sbjct: 87  DILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIKQRWGRIVNISSVV 146

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
           G     G + Y+ +KA +  FT+ +A ELAP+ V VN V PG I T++     LSEE   
Sbjct: 147 GFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAPGFIETDM--TAVLSEE--- 201

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
              ++ KE   LGR G P+EVA  + FL S+LAS ITG
Sbjct: 202 -IKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITG 238


>UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Nitrosospira multiformis ATCC 25196|Rep:
           Short-chain dehydrogenase/reductase SDR - Nitrosospira
           multiformis (strain ATCC 25196 / NCIMB 11849)
          Length = 247

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 56/187 (29%), Positives = 100/187 (53%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           A  ++I AD++  +++ ++    I+ + +LD+LVNNAG++ +  + + S  ++DR+++ N
Sbjct: 57  AEAIAIKADVSNSAEVCRLFDAAIERFQRLDILVNNAGVLLSRKMSDISDDEFDRVLDVN 116

Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527
           V+ ++Y    A    LE  G              P   AY  SK +V+Q TR  A E+  
Sbjct: 117 VKGVFYALREAAVR-LEDGGRVVNLSSTVTRLMLPNYGAYAASKGAVEQLTRVFAREVGD 175

Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           +G+  N V+PG + +E+    G SEE     + R      LGR G+P+++A  + FL S+
Sbjct: 176 RGITANIVSPGPVNSEM-FTAGKSEET----IRRMAAISFLGRVGEPEDIAGVVLFLVSE 230

Query: 708 LASNITG 728
            +  +TG
Sbjct: 231 ESRWVTG 237


>UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 524

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 56/193 (29%), Positives = 100/193 (51%), Gaps = 7/193 (3%)
 Frame = +3

Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 350
           S      D+++   +  +++  +  +G++DV+ NNAGII    + + S  Q DR++  N+
Sbjct: 320 SAAPAAVDVSRRDQVVDLVRSAVSDHGRVDVMCNNAGIIIDVPVLDLSEEQLDRVLAVNL 379

Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG-VLAYNISKASVDQFTRCVALELAP 527
           + + +    A   +   +             + P  ++AY+ISKA V Q TR +A EL P
Sbjct: 380 KGVLFGCQAAGAVMRSQRAGSIINMASGAFDTAPARLVAYSISKAGVVQITRTLAKELGP 439

Query: 528 KGVRVNCVNPGVILTELQRR------GGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 689
            GVRVN + PG++ T++ RR      G + E++   FL R+++   L R G  +++    
Sbjct: 440 DGVRVNAIAPGLVETDITRRHYAAEDGTVDEDKRERFLGRSRDLAPLRRIGTTEDIGHAA 499

Query: 690 AFLASDLASNITG 728
            +LAS+ A  +TG
Sbjct: 500 LYLASEAARFVTG 512


>UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Chromohalobacter salexigens DSM 3043|Rep:
           Short-chain dehydrogenase/reductase SDR -
           Chromohalobacter salexigens (strain DSM 3043 / ATCC
           BAA-138 / NCIMB13768)
          Length = 255

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 55/182 (30%), Positives = 91/182 (50%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           A+  S   ++  +++   +++  +   G LD+LVN AG+ E    E  +   +D     N
Sbjct: 57  ATVESAVGEIGTQAECRAVVETAVARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVN 116

Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527
           V   ++    A+PHL  S G         G+  FP    Y+ +KA+V   TR +ALELA 
Sbjct: 117 VGGTFFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAKAAVVNLTRALALELAG 176

Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           + +R+NCV PG + T++ +    +  +  A+L+       L R GKP E+A  + +LAS 
Sbjct: 177 R-IRINCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASP 235

Query: 708 LA 713
            A
Sbjct: 236 QA 237


>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 252

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 61/180 (33%), Positives = 91/180 (50%), Gaps = 1/180 (0%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D++ E +I  ++    + YG+LDV+  NAG++ T  +E+ S  +++  +  N+ + + LT
Sbjct: 63  DVSGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLT 122

Query: 372 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
             A P +   +G         G +R   G +AYN SK  +   TR +A ELAP  +RVNC
Sbjct: 123 KYAAPVMRRHEGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLADELAPHNIRVNC 182

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           V PG + T   R     E   A   E       L R   P+EVA  + FLA + AS ITG
Sbjct: 183 VCPGWVDTPFNR--PFWEHAGAGAEEEVLRGVPLRRQCTPEEVAPAVVFLAGEGASYITG 240


>UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Acyl
           carrier protein) reductase); n=4; Proteobacteria|Rep:
           Glucose-1-dehydrogenase, (3-oxoacyl-(Acyl carrier
           protein) reductase) - Janthinobacterium sp. (strain
           Marseille) (Minibacterium massiliensis)
          Length = 258

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 4/219 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLD 260
           L K GA + + GR+   LQ+V+ + D     +   A D+ + +    ++      +G +D
Sbjct: 26  LVKAGANVVIGGRDAAKLQRVATEIDPSGDHVRFHAGDIAQPATATALVDLAKQAFGGVD 85

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXG 437
           +L+NNAG+           A+YD  ++T ++  +++   A   + L   G          
Sbjct: 86  ILINNAGVFRPKAFLEVEEAEYDWFLDTILKGKFFMAQAAAKAMKLRGGGAIVQTGSLWA 145

Query: 438 IRSFPGV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611
           +++       AY+ + A V   TR +A+ELA   +R+N V PGV+ T +     ++++Q 
Sbjct: 146 LQAIGATPSAAYSAANAGVHALTRNLAIELAASNIRINTVAPGVVETPVYNTF-MTDDQV 204

Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            A L      H LGR G+P +VA  I FLAS  AS ITG
Sbjct: 205 KATLPAFNAFHPLGRNGQPADVAEAILFLASANASWITG 243


>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
           marine gamma proteobacterium HTCC2143|Rep: Short-chain
           dehydrogenase/reductase - marine gamma proteobacterium
           HTCC2143
          Length = 264

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 73/216 (33%), Positives = 107/216 (49%), Gaps = 10/216 (4%)
 Frame = +3

Query: 90  KLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           K GA + LTGR+ E  Q ++      A    I AD++KE DI   I +T++ +GKLDVL 
Sbjct: 29  KEGATVVLTGRSEEKGQAIANRLGDKAHY--IKADVSKEEDIANTISETVERFGKLDVLF 86

Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXGIRS 446
           NNAG    GTI++ +    +  ++  + S+      A+ P      G          IR 
Sbjct: 87  NNAGGPVGGTIDSIAPGDINYGVDLLLSSVVLGIRYAIEPMKANGGGVIINNTSIAAIRY 146

Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL-----SEEQY 611
             G L Y+  KA+V  +T+   +EL P G+RVNC++PG I T +   G       ++E  
Sbjct: 147 RQGNLLYSALKAAVTHYTKLAGVELGPLGIRVNCISPGAIATPIFWGGSAIANTKTDEDN 206

Query: 612 AAFLERTKETHA----LGRPGKPDEVAATIAFLASD 707
           A  LE+ K   A    L  PG  +++A    FLASD
Sbjct: 207 ARKLEKLKANLAKATPLQIPGLAEDIANGALFLASD 242


>UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Burkholderia sp. 383|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 261

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 64/216 (29%), Positives = 102/216 (47%), Gaps = 1/216 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L++ GAQ+ +  +N      V +        L +  D+ + + +  + ++   H+G+LD 
Sbjct: 29  LAQCGAQVVVAEKNAARADAVRERLGG-RDALFVETDVAEPASVAALFERVDAHHGRLDG 87

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI- 440
           LVNNAGI   G  +  SL   DRL  TN+RS++    LA P +  + G            
Sbjct: 88  LVNNAGITLHGPFDAFSLDDCDRLYRTNLRSMFQCAQLAAPRIARAGGGAIVNIASNHAG 147

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
            S PG   Y  +K  +   +R +A  LAP+ +RVN ++PG     L    G + E+  A 
Sbjct: 148 ASVPGFEMYAATKGGIVAMSRAMATSLAPQRIRVNTLSPGF---TLNAPIGAALERDPAL 204

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           L+  +  H   R  +P ++    AFL SD A+ I G
Sbjct: 205 LDAYRALHPAQRINEPADIGRIAAFLLSDAAAGIAG 240


>UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein,
           short-chain dehydrogenase-reductase (SDR) family; n=1;
           Psychroflexus torquis ATCC 700755|Rep: Probable
           oxidoreductase protein, short-chain
           dehydrogenase-reductase (SDR) family - Psychroflexus
           torquis ATCC 700755
          Length = 245

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 8/223 (3%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRN-----VENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHY 248
           L + GA+L +T R      +++L++   D   F S      D+T +S  +KII  T+D +
Sbjct: 30  LGEAGAKLVVTSRTDKFGGLDSLKEAGHDVSFFES------DITDKSVPQKIIDYTLDKH 83

Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL-TMLAVPHLLESKGXXXXXX 425
           G +D+LVNNAG+ + G +E  +    D++MN NV S++ +   +  P   +  G      
Sbjct: 84  GVIDILVNNAGVAQHGEMEEFNDELLDKIMNINVDSVFRMCRSVLTPMKKQGSGVILNIG 143

Query: 426 XXXG-IRSFP-GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLS 599
              G + + P   +AYN SKA+V   T+ +A + A + +RVN + PG   TE+ +    +
Sbjct: 144 SISGLVSNIPQPQVAYNASKAAVHMMTKSLASDFADQNIRVNAIAPGYFRTEMTKLSKET 203

Query: 600 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           E  Y  + + T     L R  + +E+ A   FL S  +S +TG
Sbjct: 204 EHWYPTWDKMT----PLNRMAETEEIGAAALFLCSPASSYVTG 242


>UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholderia
           xenovorans LB400|Rep: Putative dehydrogenase -
           Burkholderia xenovorans (strain LB400)
          Length = 291

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 66/189 (34%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
 Frame = +3

Query: 174 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNV 350
           ++SI  D+  ES ++    +T++H+G+ DVL+NNA  +   T IE   +A +DR +  N+
Sbjct: 69  SVSIECDVADESSVKNAAGRTVEHFGRCDVLINNAATLAPATSIEKLLVADWDRTLAINL 128

Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA-YNISKASVDQFTRCVALELAP 527
           R ++ LT   +  L+ ++G            + P     Y  SKA+V  FTR  A+E  P
Sbjct: 129 RGVF-LTTKYLGALMLNQGSGSIVNIASIAATAPNASPQYGASKAAVLAFTRHTAVEWGP 187

Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYA--AFLERTKETHALGRPGKPDEVAATIAFLA 701
           +G+R N V+PG I T       LSE  YA    L R        R G P ++A  +AFLA
Sbjct: 188 RGIRANAVSPGFIRTP------LSESNYAEPEMLARRSNMVPSRRLGLPGDIAEAVAFLA 241

Query: 702 SDLASNITG 728
            D AS I G
Sbjct: 242 GDGASFING 250


>UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5;
           Bacteria|Rep: Glucose 1-dehydrogenase - Synechococcus
           sp. (strain CC9311)
          Length = 265

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 62/219 (28%), Positives = 112/219 (51%), Gaps = 5/219 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRN-VENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKL 257
           +  LGA++ +  R+  E  +++ ++  +    ++ + AD++K  D++ +I   +  +GK+
Sbjct: 35  VGSLGAKVVIDYRSHPERTEELIEEVGELGGQSIGVQADVSKLVDLQHLIDTAVQTFGKI 94

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
           DV+VNNAGI    +I +TS   +D++MN N+R +++ T  A   ++ S+G          
Sbjct: 95  DVMVNNAGIETRTSILDTSPDDFDKVMNVNLRGVFFATQYAAKQMI-SQGSGGRIINISS 153

Query: 438 IRS---FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
           +      P    Y ++K  V   TR   +ELA KGV +  V PG + T +      S   
Sbjct: 154 VHEDWPMPNNTPYCVAKGGVRMLTRTAGVELAGKGVSIVNVGPGAVATPIND----STMN 209

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725
               L +      +GR  +P E+A+ +AFLA + AS +T
Sbjct: 210 DPELLAKLNAAIPIGRMAQPAEIASVVAFLAGNGASYMT 248


>UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Rhizobiales|Rep: Short-chain
           dehydrogenase/reductase SDR - Methylobacterium sp. 4-46
          Length = 252

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 70/241 (29%), Positives = 119/241 (49%), Gaps = 4/241 (1%)
 Frame = +3

Query: 18  FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD-CDKFASTLSITAD 194
           FAG+ V                L++ GA+  L GR +E L+ V+ +   +  S L +  D
Sbjct: 5   FAGQTVVVTGAGTGMGRAAAIRLAREGARSVLVGRRLEPLEAVAAEIAAEGGSALPVACD 64

Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLT 371
           +   +++E ++++     G++D L  NAG++     +  T    ++ L+ TN+   +   
Sbjct: 65  IGNPAEVEAMVRQATRANGRIDGLFANAGVLGAFKPLAETDATDFEELVGTNLLGTFLSI 124

Query: 372 MLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
             ++PHL   +G          + S  PG  AY  +K ++      +ALE  P+ VRVN 
Sbjct: 125 KHSLPHL---RGGAVVINASWTVNSVMPGAGAYAATKGALIAMMHTLALEQGPRDVRVNS 181

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHA-LGRPGKPDEVAATIAFLASDLASNIT 725
           ++PG+ILT +     + +  ++A L      HA LGR G PD+VA T+A+L SD A  +T
Sbjct: 182 ISPGIILTPM--ADAVLDPAFSAKL----AAHAPLGRNGTPDDVAGTVAWLLSDDARFVT 235

Query: 726 G 728
           G
Sbjct: 236 G 236


>UniRef50_A4T6Z1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium gilvum
           PYR-GCK
          Length = 291

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 67/224 (29%), Positives = 113/224 (50%), Gaps = 9/224 (4%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
           L+  GA ++L GR  E L++ + +  +    +T  + AD++K   I + + +  D  G+L
Sbjct: 56  LAGSGADIALVGRTREPLERRAAEIAQRWGVNTYPVQADMSKWDQIHRGVAEAHDKLGRL 115

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 434
           D+++NN  ++  G  E  +  Q D  +  ++  + Y    A+ +LL +  G         
Sbjct: 116 DIMINNPVMVAAGPFEKQTKEQIDLTVLGSLTMMMYGAHAALEYLLPQGSGVIINIGSVG 175

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR---GGLSEE 605
           G     G+  YN  K+ V  FTR +A E+AP+GV V CV PG+++ E  ++       ++
Sbjct: 176 GRVQQRGLTVYNACKSGVIGFTRNLAHEVAPRGVNVFCVAPGIMIKEQMKQYLFDPQDDQ 235

Query: 606 QYA---AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           Q A   A +E       LGR   P+E A  +AFLAS+ AS + G
Sbjct: 236 QRAGRGAIIESITHQVQLGRASLPEEAANMVAFLASEAASYMCG 279


>UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL
           12
          Length = 256

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 70/216 (32%), Positives = 116/216 (53%), Gaps = 5/216 (2%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++++   N E  + V+    + A  +++T D++K +D+ + +++TID +G++D+ +NN
Sbjct: 36  GARVAIVDLNGEGAKAVADALQQNA--IAVTCDVSKGADVSRAVQETIDAFGRVDIAINN 93

Query: 276 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSF 449
           AG         +     + R+   NV SI++ T   VPH  +   G         GIR  
Sbjct: 94  AGWSHRNQPALDVDFETFKRVYEVNVDSIFHATHALVPHWRDIGGGVMINVGSTAGIRPR 153

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE-LQRRGGLSE--EQYAAF 620
           PG+  YN SK +V+  T+ +A+ELAP  VRV  + P +  T  L+   G+ +  E  A F
Sbjct: 154 PGLSWYNSSKGAVNMMTKTLAVELAPDRVRVCGLAPVMGATPLLETFMGMPDTPENRAKF 213

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           L     T  LGR  +P+++A    +LASD A+ ITG
Sbjct: 214 L----GTIPLGRLCEPEDMANAALYLASDEANFITG 245


>UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1;
           Mycobacterium smegmatis str. MC2 155|Rep:
           2-deoxy-D-gluconate 3-dehydrogenase - Mycobacterium
           smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 254

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 64/240 (26%), Positives = 111/240 (46%), Gaps = 2/240 (0%)
 Frame = +3

Query: 15  NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 191
           N  GKV                 L   GA +++  R    L+    D        L+ + 
Sbjct: 7   NLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACST 66

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D+T E+ +E+++  T++ +G++D+LVNN+GI+ T  +   S  ++DR++ TN+R  +  T
Sbjct: 67  DITDEASVERLVDATVETFGRVDILVNNSGIVATTPLIEQSADEWDRVVATNLRGTFLAT 126

Query: 372 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
                HL+ +  G          ++      AY+ SKA V  FTR +A+E A   ++VN 
Sbjct: 127 RAVGRHLVAQRSGKVINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVNA 186

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           + PG   T L      ++   AA + R        R G+P+E+ + +  LA   +  +TG
Sbjct: 187 IAPGYFATSL-NADMRADADMAAKVVRAIPAR---RMGEPEELTSWLLLLAGSASDFMTG 242


>UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella woodyi ATCC
           51908
          Length = 251

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 71/238 (29%), Positives = 115/238 (48%), Gaps = 2/238 (0%)
 Frame = +3

Query: 21  AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 200
           AGK +               + S +GA++ LTGRN E L +  KD    ++ L   ADL 
Sbjct: 6   AGKTILVTGASSGLGKAIAIYFSTVGARVVLTGRNEERLHETLKDMSG-SNHLYFIADLA 64

Query: 201 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT-ML 377
           K    + ++     + G LD +++ AGI +T  ++      +D + NTNV+S  ++   L
Sbjct: 65  KVESTQAMMDTVFANVGALDSVIHCAGIQKTLPLQALKEHHFDDIFNTNVKSAQFIAKFL 124

Query: 378 AVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554
                  S+G           +   P + +Y+ SKA++   ++ +A+ELA + +RVNC+ 
Sbjct: 125 RKKGRYNSQGTSLVLLSSVAAVCGEPAISSYSASKAALLGLSKSLAIELARQNIRVNCIA 184

Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           PG + TE+      S++  A   E     H LG  GKP+ +A    FLASD +  ITG
Sbjct: 185 PGHVGTEMAIE--FSKQLTAEQRENILLKHPLGL-GKPEYIAQAAEFLASDKSCWITG 239


>UniRef50_A0GDY0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=5; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Burkholderia
           phytofirmans PsJN
          Length = 249

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 63/211 (29%), Positives = 102/211 (48%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA + + GR +  +     +    A+ L  T DL   +  +++     + +G LD+ V N
Sbjct: 30  GAHVLIVGRRLAAVNAAVAELGDRATGL--TGDLADPATHDRVASLVEERFGGLDIYVAN 87

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AG+         SL +YD  + TN RS+++  +  V   L + G           + F G
Sbjct: 88  AGVNTIARSHLVSLEEYDAQVATNTRSVFF-GVQKVASQLRNGGAILLTSSIASSKVFEG 146

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
             AY  SKA+++ F R  ALE   +G+RVN ++PG + T +  + G++     AF     
Sbjct: 147 HAAYAGSKAAIEAFARSWALEFKERGIRVNVISPGPVDTPILSKLGIAVADRPAFEAAVA 206

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
           E   LGR G+ +E+A    FL SD +S +TG
Sbjct: 207 EKIPLGRLGRAEELAQAALFLVSDESSFVTG 237


>UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1;
           Archaeoglobus fulgidus|Rep: 2-deoxy-D-gluconate
           3-dehydrogenase - Archaeoglobus fulgidus
          Length = 281

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 64/221 (28%), Positives = 112/221 (50%), Gaps = 6/221 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L+  G  + + GR +E L+K+ +  +K     L++  D+T E D+  ++ +T++ +G++D
Sbjct: 55  LADFGCDVVVVGRRLEVLEKLKESIEKLGQRALAVKCDITSEEDVANLVNRTVEEFGRID 114

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           +LVN AGI      E   L  ++++M+ NV  ++ +       +++  G          +
Sbjct: 115 ILVNCAGINIPKPAEEYPLEDWNKVMDANVTGVFLVCREVGKVMVKQNG--GKIINVSSV 172

Query: 441 RSFPGV----LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
           RS  G+    +AY  SKA+V+  T+ +A E A   + VN + P VI T L        E 
Sbjct: 173 RSSYGMPKNYIAYCSSKAAVNMITKQLACEWAKYNILVNAIAPTVIATPLTAHIMKDPE- 231

Query: 609 YAAFLERT-KETHALGRPGKPDEVAATIAFLASDLASNITG 728
               L +T K    LGR G PD++   + F ASD ++ +TG
Sbjct: 232 ----LSKTMKSRILLGRWGYPDDLIGAVVFFASDASNFVTG 268


>UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family member
           4; n=9; Eutheria|Rep: Dehydrogenase/reductase SDR family
           member 4 - Sus scrofa (Pig)
          Length = 260

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 63/218 (28%), Positives = 116/218 (53%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + ++ R  EN+ + V+    +  S       + K  D E+++   ++ +G +D
Sbjct: 34  LAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVNLHGGVD 93

Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
           +LV+NA +    G I + +   +D++++ NV++   +T   VP + +  G         G
Sbjct: 94  ILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVG 153

Query: 438 I-RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
               FP +  YN+SK ++   T+ +A+ELAP+ +RVNC+ PG+I T   +   + +    
Sbjct: 154 AYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDK---- 209

Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           A  E  KE+  + R G P++ A  ++FL S+ AS ITG
Sbjct: 210 ARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITG 247


>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
           Oxidoreductase - Oceanobacillus iheyensis
          Length = 244

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 65/213 (30%), Positives = 103/213 (48%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272
           GA+L L   N E    +  +     S  + I AD+T E  ++ I    ID +GK+D+L N
Sbjct: 29  GAKLILVDMNEEKGASIEAELKSQGSEAIFIKADVTNEEQVKNIYTTAIDTFGKVDILFN 88

Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSF 449
           NAGI      E  + A++ + +  ++  ++ +   A+   L++  G         G    
Sbjct: 89  NAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVAQAAIKEFLKAGSGVIVNTASMYGWVGS 148

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
           PG  AYN +KA V   TR + LE A + +RVN + PG I T +     L +    A +  
Sbjct: 149 PGSAAYNAAKAGVVNLTRSLGLEYAARNIRVNALCPGFIDTAI-----LGDSDREALINT 203

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           T     + R GK +E+A  + F+ASD +S +TG
Sbjct: 204 T----PMNRLGKSEEMAKAVLFMASDDSSFMTG 232


>UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=4; Bacteria|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Rhodopirellula baltica
          Length = 273

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 72/221 (32%), Positives = 108/221 (48%), Gaps = 6/221 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-----TLSITADLTKESDIEKIIKKTIDHY 248
           L+  GA + L  RN    Q+ S   +K A      ++ I AD+T E+D+  +++  +D  
Sbjct: 48  LASAGANVCLVSRNE---QEASAAAEKIAGEYPVRSIGIGADVTVEADVANMVQACVDQL 104

Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXX 425
             LDVL+N+AGI   G+I+  SL Q+ ++ +TNV  ++     A   + ++  G      
Sbjct: 105 SGLDVLINSAGINVRGSIDELSLEQFRQVQSTNVDGMWLCCKHASSVMKKNGSGRIINLA 164

Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 605
              G+        Y  SK +V Q TR + LELAP  V VN + PG  LT +      SEE
Sbjct: 165 STLGLVGLANRTPYASSKGAVVQMTRALGLELAPHNVTVNAICPGPFLTPMNVPIADSEE 224

Query: 606 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                +  T    AL R G+  E+     FLASD +S +TG
Sbjct: 225 AKRFIVGAT----ALERWGQMQEIQGAAIFLASDASSYMTG 261


>UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 259

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 65/240 (27%), Positives = 119/240 (49%), Gaps = 4/240 (1%)
 Frame = +3

Query: 21  AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKV-SKDCDKFASTLSITADL 197
           AGKV                  +  GA++++  R+ +  + + S+  D     +   AD+
Sbjct: 10  AGKVAVVSGGAGGCGGAASELFAAQGAKVAIIDRDGDAAETLASRLRDAGLQAIGFGADV 69

Query: 198 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 377
           +K++++++ +    + YG  D+L N+AG +      +   +++D LM  NV+S++ +T  
Sbjct: 70  SKQAEVQQAVNAAREQYGNADILFNHAGTLIVKPFLDIEESEWDWLMGVNVKSMFLMTKA 129

Query: 378 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554
            +P +LE  +G          + + PG + Y+ +K +   F R +A+E   +G+R N + 
Sbjct: 130 VLPQMLEKGRGSIVCTSSISAVCATPGEVLYDATKGACHMFARAIAVEYRDRGIRCNALA 189

Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHAL--GRPGKPDEVAATIAFLASDLASNITG 728
           PG I T    R  L + Q A  ++ T+   A+  GR  +P EVAA   FLASD +S + G
Sbjct: 190 PGFIRTPHGMR-ELKDLQ-AMGVDATEAAIAVQQGRLCEPSEVAAAALFLASDESSFVNG 247


>UniRef50_Q3WHY3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 346

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 63/211 (29%), Positives = 97/211 (45%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           G  +++TG+N E L             L   AD    +D + +  +  D +G LD +  N
Sbjct: 126 GFAVAITGQNPETLAAARHVLPD--DVLVQRADARVLADADALAAELRDRFGHLDAVFLN 183

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           A + +  +  + +   Y      NV+  ++     +P LL   G           RSFPG
Sbjct: 184 AAVAQPSSFSSVTEESYKEHFGVNVKGQFFTLQRVLP-LLRDGGTVVFNSSRLVARSFPG 242

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
           +  Y  +K +V    R +A+ELAP+ +RVN V+PG + T    + GLS  +  +      
Sbjct: 243 MSLYVATKGAVASMARALAVELAPRRIRVNVVSPGPVDTPALAKQGLSAAELTSLRTTLT 302

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
               LGR    +EVA T+AFL SD AS +TG
Sbjct: 303 AKVPLGRIASDEEVAHTVAFLVSDAASYLTG 333


>UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacter
           caesariensis|Rep: Pteridine reductase - Neptuniibacter
           caesariensis
          Length = 246

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 63/186 (33%), Positives = 99/186 (53%)
 Frame = +3

Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 350
           S  + +ADL     + ++ +  + H+G+L++L+NNA       IE TSL Q+D L+N+N+
Sbjct: 57  SAKTFSADLNNLEQLNQLAEDILRHFGQLNLLINNASTFYPTPIEETSLHQWDELINSNL 116

Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
           R+ Y+L       L ES G           R  PG   Y+I+KA ++  T+ +A ELAP+
Sbjct: 117 RAPYFLCATLSKTLRESNGCIINMIDIHAQRGLPGYPIYSIAKAGLEMLTKSLAKELAPQ 176

Query: 531 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 710
            VRVN ++PG IL   Q    +S  + A  L++      LGR G  +++A    +L+   
Sbjct: 177 -VRVNGISPGAILWPEQE---VSSTEKANILDKV----LLGRLGVEEDLAQAAIYLSQ-- 226

Query: 711 ASNITG 728
           A  ITG
Sbjct: 227 AEYITG 232


>UniRef50_Q2AGJ3 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=1; Halothermothrix orenii
           H 168|Rep: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Halothermothrix orenii H
           168
          Length = 243

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 61/190 (32%), Positives = 99/190 (52%), Gaps = 1/190 (0%)
 Frame = +3

Query: 162 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 341
           K  +TL + ADLT  +   K++++ I  +G+LD++VN+AGI   G IE TS A++++   
Sbjct: 44  KGENTLYVKADLTDYNQARKVVEEGIAKFGQLDIVVNSAGITGVGNIETTSPAEFEKQFA 103

Query: 342 TNVRSIYYLTMLAVPHLLESKG-XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE 518
            NV   +     AV  L +  G          G++  P  +AY  SKA+V  FT+C+AL+
Sbjct: 104 VNVFGTFNTCKAAVGELKKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCMALD 163

Query: 519 LAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFL 698
           L P  +RVN + PG+  T + +      +      +   E + L R    D++A    FL
Sbjct: 164 LGP-DIRVNAIMPGLTETPMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFL 222

Query: 699 ASDLASNITG 728
           A++ +  ITG
Sbjct: 223 ATEDSGFITG 232


>UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1;
           Desulfitobacterium hafniense Y51|Rep: Putative
           uncharacterized protein - Desulfitobacterium hafniense
           (strain Y51)
          Length = 262

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 61/216 (28%), Positives = 109/216 (50%), Gaps = 5/216 (2%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269
           G  L++T R   + ++++KD +       L I+AD + + DI++++ +T++ +GK+D+L+
Sbjct: 38  GCDLAITSRTPADCERIAKDIETLYGVKCLGISADSSNKDDIDRVVAQTVETFGKIDILI 97

Query: 270 NNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXXGI 440
           NNAGI  +T  + + +   +  ++NTN++ ++         + +    G         G+
Sbjct: 98  NNAGISGKTAALLDQTEDDFMNVINTNLKGVFQFAQAVAAQIAKQGKGGRIVNIASVGGL 157

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
                V  Y  SKA V   T+ +A E A  G+ VN V PG ++TEL +      E  A  
Sbjct: 158 IGGKSVAPYGASKAGVLSLTKTMANEWARYGITVNAVCPGYVITELNQDIFADPEIKAKM 217

Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            +RT     + R G  +EVA  +  + SD  S +TG
Sbjct: 218 EKRT----PVRRLGSVEEVAGPVLAMVSDSFSYMTG 249


>UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=28; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 253

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 70/220 (31%), Positives = 111/220 (50%), Gaps = 6/220 (2%)
 Frame = +3

Query: 87  SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           ++LGA++ +     E  Q+V+   +      +++  D+T+++ +  ++   +  +G+LD+
Sbjct: 27  AELGAKVVVADLRAEAAQQVAAAIESAGGQAIAVHVDVTQDASVADMVAAAVKRFGRLDI 86

Query: 264 LVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX-G 437
           LVNNAG       +  T    +DR+  TNV+SIY     AVP   +  G          G
Sbjct: 87  LVNNAGTTHKNQPMLETDEKTFDRVYATNVKSIYLGARHAVPLFRQQGGGVIINIASTAG 146

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR---RGGLSEEQ 608
           +R  PG+  Y  +K +    T+ +A+ELAP  +RVN +NP +  T L      G  SEE 
Sbjct: 147 LRPRPGLSWYAGTKGAAITLTKAMAVELAPDKIRVNAINPVMGETGLLADFLPGADSEE- 205

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                ++   T  LGR  KP ++A   AFLASD A  ITG
Sbjct: 206 ---VRQKIIATIPLGRLSKPIDIAKATAFLASDEADFITG 242


>UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Sphingomonas wittichii RW1|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
          Length = 250

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 56/180 (31%), Positives = 88/180 (48%)
 Frame = +3

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
           AD+T    +  + +     YG+ D+LVNNAG++    I      ++DR+   N +S + +
Sbjct: 62  ADVTSAVQVATLGQHVRSAYGRADILVNNAGMLSFAPIVGADANEWDRVQKVNCKSAFLM 121

Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
                P L+  KG         G++      AY+I+KA +   T+  A+EL P G+RVN 
Sbjct: 122 IRTFAP-LMAGKGAIINISSSAGLKPTANTAAYSIAKAGLLMLTQIAAMELGP-GIRVNA 179

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           + PG + T++              +E   E   + R G+P E+A  +AFLASD AS I G
Sbjct: 180 IAPGPLDTDMPHSYLKGHPHKGQIMEHMIERTIVKRLGQPGEIAEVVAFLASDAASYING 239


>UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Dehalococcoides|Rep: Short-chain
           dehydrogenase/reductase SDR - Dehalococcoides sp. BAV1
          Length = 265

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 64/222 (28%), Positives = 104/222 (46%), Gaps = 7/222 (3%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + +   N+E  QK   +         +I AD++  +D +K+I  T+  +G LD
Sbjct: 32  LAEAGASIMIPDLNLEVAQKTVAEIKALGGKATAIQADVSNINDTQKVIDATLKAFGDLD 91

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXX 434
           ++VNNAGI       + + A +D+ +  N++ + + +  A   ++ +K  G         
Sbjct: 92  IMVNNAGIYRFMPAIDMTEAMWDKTLGINLKGLMFFSQAAAKAMMAAKHGGKIINIASID 151

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILT----ELQRRGGLSE 602
           G R    +  Y+ SK  V   T+ +A E AP G+ VN V PG I T     L   G +S 
Sbjct: 152 GFRPTGNLAHYDASKGGVIMLTKAMAQEWAPHGILVNAVAPGGINTPGASALMPSGSMSA 211

Query: 603 EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           EQ     +       L R G+PD++   + FL S  A  I G
Sbjct: 212 EQLMELSKSFVAKLPLKRMGEPDDIGKVVLFLTSAAADYIVG 253


>UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=4; Methanosarcina|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase -
           Methanosarcina acetivorans
          Length = 242

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 53/170 (31%), Positives = 93/170 (54%), Gaps = 3/170 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC--DKFASTLSITADLTKESDIEKIIKKTIDHYGKL 257
           L+K G  + +  RN E+  K ++D   D  +    I  D+  E D+ ++I +TID  G+L
Sbjct: 31  LAKEGVNIIIAARN-ESESKETQDQLKDMGSKAFEIPVDVRNEEDVRRLISRTIDKCGRL 89

Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434
           D+L+NNAG+     +E T++ +YD++++TN++ ++  T  A+P+L  SK G         
Sbjct: 90  DILINNAGVALKKRLEETTVEEYDKIIDTNLKGVFLCTKYAIPYLRRSKNGKIINISSIG 149

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 584
           G+   P    Y  SK  V+  T  +A EL  + ++V  + PG + T++ R
Sbjct: 150 GLHGIPEFSVYCASKFGVNGVTEAIAAELEGQ-IKVYSICPGAVDTDMYR 198


>UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=18;
           Bacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 255

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 63/220 (28%), Positives = 108/220 (49%), Gaps = 5/220 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
           L+  GA ++  GR+     + + +       LSI AD +    +++++ +T+  +GK+D+
Sbjct: 29  LAAAGADIAAAGRSAPTETQAAVEA-LGRKFLSIKADFSSIEPVQRVVDETVAAFGKVDI 87

Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXG 437
           LVNNAGII        S A +D +M+TN++ +++LT       L+   +G          
Sbjct: 88  LVNNAGIIRRADSIEFSEADWDAVMDTNLKVVFFLTQAFAKQALKQGFEGGQAKVINIAS 147

Query: 438 IRSFPG---VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608
           + SF G   V +Y  SK+ +   T+ +A E A KG+ VN + PG   T         +++
Sbjct: 148 LLSFQGGIRVPSYTASKSGLAGLTKILANEWATKGINVNAIAPGYFDTNNTEALRADQDR 207

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            AA L R       GR G+P+++     FLAS  +  + G
Sbjct: 208 NAAILARI----PAGRWGRPEDIGGAAVFLASSASDYVQG 243


>UniRef50_Q8RDH9 Cluster: Dehydrogenases with different
           specificities; n=4; Bacteria|Rep: Dehydrogenases with
           different specificities - Thermoanaerobacter
           tengcongensis
          Length = 245

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 59/191 (30%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
 Frame = +3

Query: 159 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLM 338
           + F+      AD++    ++++I +    +G++D L+NNAGI +       +   +DR+M
Sbjct: 51  ENFSYAEIFQADISNRKQVDEMIDEIYRKFGRIDYLINNAGIAQIKPFVEITEEDWDRMM 110

Query: 339 NTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515
           N N++ ++  T   + ++L  K G         GI      + Y+ SK  V  FT+ +A 
Sbjct: 111 NVNLKGLFNCTQSVLRYMLPKKQGSIINISSIWGISGASCEVHYSASKGGVIAFTKALAK 170

Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695
           EL P  +RVNC+ PGVI T +     L+ E     +E       L   GKP++VA  + F
Sbjct: 171 ELGPSKIRVNCIAPGVIDTRMNNI--LNGEDKKHLIEEI----PLMSIGKPEDVANAVLF 224

Query: 696 LASDLASNITG 728
           L SD A+ ITG
Sbjct: 225 LLSDKANFITG 235


>UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: Gdh
           protein - Bradyrhizobium japonicum
          Length = 278

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 62/185 (33%), Positives = 88/185 (47%), Gaps = 3/185 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362
           + AD+  E DI  + +  +  + +LD LVNNAG       +   +  Y R+++ N+    
Sbjct: 78  VQADIGSEQDIAAMFETILARWKRLDCLVNNAGFQRESPSDALDVETYRRIIDVNLNGAV 137

Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSF---PGVLAYNISKASVDQFTRCVALELAPKG 533
                A+ H + ++G          +      PG LAY+ISK  +   TR +ALE A  G
Sbjct: 138 LCAQKALAHFV-ARGGGGSIINCSSVHQIIPKPGYLAYSISKGGLANLTRTLALEFARHG 196

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           +RVN V PG I T +        E+             LGR G P+E+AA  AFLASD A
Sbjct: 197 IRVNAVGPGAIDTPINAAWTGDPEKRGVVTSHI----PLGRVGTPEEIAAVFAFLASDDA 252

Query: 714 SNITG 728
           S ITG
Sbjct: 253 SYITG 257


>UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 258

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 64/185 (34%), Positives = 97/185 (52%), Gaps = 6/185 (3%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D+T+E+D  ++++      G+LDVLVNNAGI  +  IE  +   +DR +N N++S++   
Sbjct: 62  DVTQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGC 121

Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG--VRVN 545
              +  + +  G          I   P  LAY+ SKA V   ++ VAL  A KG  +RVN
Sbjct: 122 KHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVALHCAEKGYAIRVN 181

Query: 546 CVNPGVILTEL----QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
            ++PG I T L       G L+ ++  A   R      L R G PDEVA  + +LASD +
Sbjct: 182 SLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDES 241

Query: 714 SNITG 728
           + +TG
Sbjct: 242 TYVTG 246


>UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 262

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 4/183 (2%)
 Frame = +3

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368
           D+T E+D+ ++  + + H+G+LDVLVNNAGI          +LAQ+ R+++ NV  ++  
Sbjct: 69  DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128

Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545
           T  A+PH+     G         GI   P V AY+ SKA+V    +  A+  A K +R N
Sbjct: 129 TRAAIPHIDAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAVRMMAKVDAMLYAAKNIRAN 188

Query: 546 CVNPGVILTELQRRG--GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
            V+PG I T +       + ++   AF E  +    + + G P ++AA I +L S     
Sbjct: 189 SVHPGYIRTPMLEDAFRQMGQDPDRAF-EYMQTNVPMAKIGSPRDIAAGILYLVSPAGRY 247

Query: 720 ITG 728
           +TG
Sbjct: 248 VTG 250


>UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aurantiacus
           J-10-fl
          Length = 249

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 4/243 (1%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSIT 188
           M F GKV                 L   GA + L  R +E L+ V +  D K A TL++ 
Sbjct: 1   MEFEGKVALVTGAGTGIGEAIAERLLAGGALVVLVSRRLEPLELVCRRIDPKGARTLALE 60

Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYDRLMNTNVRSIY 362
           AD+     +E  +K+TI+ +GKLD+ VNNAG+       +++     +  +++T++  I+
Sbjct: 61  ADVRNPMAMEAAVKRTIERFGKLDMAVNNAGVTGPAGVPVQDVEAEIWREVIDTDLTGIF 120

Query: 363 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
           Y     +P +L    G         G+    G+ AY  +K  V   TR  ALELA   +R
Sbjct: 121 YSMKYEIPAMLANGSGAIVNMSSANGLVGLAGMAAYTAAKHGVIGLTRSAALELAESNIR 180

Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719
           V  V PG + T      G     + A L      H + R    +EVA  +A+L S+ A+ 
Sbjct: 181 VCAVAPGYVATPRIMDSGKEVTDWMASL------HPMKRLATREEVADFVAYLLSERAAF 234

Query: 720 ITG 728
           +TG
Sbjct: 235 MTG 237


>UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Ralstonia|Rep: Short-chain dehydrogenase/reductase
           SDR - Ralstonia pickettii 12D
          Length = 254

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 59/187 (31%), Positives = 93/187 (49%)
 Frame = +3

Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347
           A  +++ AD++  + ++ +     + +G +D+LVNNAGI+E   + +  LA +D    TN
Sbjct: 64  AHAIAVQADVSDAASVDAMTGTVREAFGAIDILVNNAGILENQPVGSIDLASFDVQFRTN 123

Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527
             S   +T   +PH+    G           R   G+  Y  SKA+V   T   A+EL P
Sbjct: 124 AFSTILVTQAVLPHVPAPGGRIVNVSSSLVYRPRAGLAVYAASKAAVGALTHAFAVELGP 183

Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707
           + + VN V P   LT       + +E  A    R +++  LGR  +P ++A  +AFLASD
Sbjct: 184 RNITVNAVAPA--LTRTDMTAPIPDEVKA----RMRDSTPLGRLAEPGDIADAVAFLASD 237

Query: 708 LASNITG 728
            A  ITG
Sbjct: 238 DARWITG 244


>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2143
          Length = 259

 Score = 97.9 bits (233), Expect = 2e-19
 Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 5/191 (2%)
 Frame = +3

Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 347
           + + +  D+TKESD++ +I+ T   YG +D   NNAGI IE G +   +  ++D +M  N
Sbjct: 57  NAIFVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEKGELSKGTEDEFDSIMAVN 116

Query: 348 VRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
           V+ ++      +  ++ +  G         G+ + P +  Y  SK +V   T+  A+E A
Sbjct: 117 VKGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVENA 176

Query: 525 PKGVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695
             G+R+N V PGVI T +  R  +   SE   +    R    H + R G  +E++  + +
Sbjct: 177 RNGIRINAVCPGVIDTNMFNRSRMFDRSEVSASETRARVNAIHPMDRIGTAEEISDAVLY 236

Query: 696 LASDLASNITG 728
           L SD AS ITG
Sbjct: 237 LCSDGASFITG 247


>UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN)
           REDUCTASE; n=6; Brucellaceae|Rep:
           3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella
           melitensis
          Length = 249

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 65/213 (30%), Positives = 113/213 (53%), Gaps = 2/213 (0%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ L   NV+ ++    D    ++ +SI AD+++++D+E++ +   + +G++D++VNN
Sbjct: 30  GARVVLADVNVKRVEDGLADIS--SNGISIQADVSRKNDMERVARTAFEEFGRIDIMVNN 87

Query: 276 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGIRSF 449
           AG       + +     +D ++  N++++YY T L VP +  +  G         G+   
Sbjct: 88  AGFTHRNMPLTDVDEHNFDLIVAVNMKALYYSTQLVVPIMEHQGGGVIINTASATGLHPR 147

Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629
            G+  Y  SK+ V   T+ +ALELA + +RVNC+ P     E   +  L+E+   A    
Sbjct: 148 KGLTWYCASKSWVVSATKAMALELAERNIRVNCLCPAESDGE-GLKMFLAEDTPEA-RAA 205

Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728
            K T  LGR   P +VA    +LASD AS +TG
Sbjct: 206 LKSTIPLGRFSTPKDVAEAALWLASDDASMVTG 238


>UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3;
           Alphaproteobacteria|Rep: Oxidoreductase - Zymomonas
           mobilis
          Length = 243

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 59/184 (32%), Positives = 97/184 (52%)
 Frame = +3

Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
           LSI AD +     +K+I +T  H+G++DVLV NAG++    I+  S+   + ++N N+RS
Sbjct: 56  LSIQADGSTVEGNKKVISETAKHFGRVDVLVCNAGMLSYKNIDQVSVDDINDMLNLNLRS 115

Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536
           +      AV HL              G   F G+  Y+ +KA +  F + VA +L  K +
Sbjct: 116 VMVEVSEAVRHLPSGGRIILIGSTFAGRAPFAGISLYSAAKAGLRGFAKGVARDLGQKAI 175

Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716
            +N + PG I T++    G + +  ++F   TK+       G+ D++A T++FLAS  + 
Sbjct: 176 TINVIEPGPINTDMNPADGEAFDLISSF-TATKDY------GQVDDIARTVSFLASSESG 228

Query: 717 NITG 728
           NITG
Sbjct: 229 NITG 232


>UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp.
           HTCC2601|Rep: FabG3_1 - Roseovarius sp. HTCC2601
          Length = 249

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 70/241 (29%), Positives = 119/241 (49%), Gaps = 2/241 (0%)
 Frame = +3

Query: 12  MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191
           M+  GKVV                 ++ GA + L     + ++ +++D    A  L++  
Sbjct: 1   MDVTGKVVLISGAARGMGAHEARRFAEAGACVILGDVLDDEVRALAEDLGD-ARALAVPL 59

Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
           D+++  D E  +   +  +G++DVLVNNAGI+    IE  S  +++++++ N+   +   
Sbjct: 60  DVSRSEDWEGAVAAGVARFGQIDVLVNNAGILRFSNIETCSDEEWEKVLSINLGGAFKGI 119

Query: 372 MLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548
              +P +  +  G         G+++F GV AY  SK  +   TR  A+ELA  G+RVN 
Sbjct: 120 RAVLPVMKRNGSGSIINISSTAGLKAFGGVSAYVTSKFGIRGLTRAAAVELAGHGIRVNS 179

Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHA-LGRPGKPDEVAATIAFLASDLASNIT 725
           V+PG I T+      + E+ Y  F       H  + R G+PDE+A  + +LASD +S  T
Sbjct: 180 VHPGNIDTD------MVEDLYPNF------NHVPMKRMGQPDEIANLVIYLASDASSFST 227

Query: 726 G 728
           G
Sbjct: 228 G 228


>UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Sinorhizobium medicae
           WSM419
          Length = 253

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 66/211 (31%), Positives = 100/211 (47%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GA++ LTGR+  N+ ++ ++       LS  +D+   +DI  +        G +D+L  N
Sbjct: 30  GAEVLLTGRSESNIARIREEFGPRVHALS--SDIAHLNDIAILGAAAGQKLGAIDLLHIN 87

Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455
           AGI E    +  S A YDR  + N +  ++      P L+   G               G
Sbjct: 88  AGISELEPFDQVSEASYDRQFSVNTKGAFFTVQRLAP-LIREGGSIVFTSSVADEGGHQG 146

Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635
           +  Y+ SKA++  F   +A EL P+G+RVN V+PG I T  +   GL+E Q A F     
Sbjct: 147 MSVYSASKAALVSFASVLAAELLPRGIRVNSVSPGFIDTPTKGAAGLTEAQRAEFKALGD 206

Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728
               + R G  DEVA  + FLA + A+  TG
Sbjct: 207 AITPMRRNGTADEVARAVLFLAFE-ATFTTG 236


>UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - unidentified eubacterium SCB49
          Length = 256

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 58/185 (31%), Positives = 98/185 (52%), Gaps = 3/185 (1%)
 Frame = +3

Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVRSI 359
           I+ DLTKE+D   ++K+T++  G LD+L+NNAG ++    +       + ++M+ N+ S+
Sbjct: 64  ISGDLTKEADANTLVKQTVEALGGLDILINNAGSLVARKLLSEMETEFWHKVMDINLTSM 123

Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRS--FPGVLAYNISKASVDQFTRCVALELAPKG 533
            ++T  A P+L +++            R    PG L Y+ SK ++  FTR ++ EL  +G
Sbjct: 124 MFVTRAASPYLAKNENSSIVNLASLAGRKGGHPGSLVYSTSKGAILTFTRALSTELGAQG 183

Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713
           +RVN V+PG+IL         ++E  A     T     + R G   +VA  + +LAS+  
Sbjct: 184 IRVNAVSPGLILGTSFHNTHTTKESAA----ETTAGIPIQRAGNAADVARAVLYLASEYD 239

Query: 714 SNITG 728
             ITG
Sbjct: 240 GFITG 244


>UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Leeuwenhoekiella blandensis MED217
          Length = 257

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 59/220 (26%), Positives = 112/220 (50%), Gaps = 5/220 (2%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA++ ++  + E  +KV +   +     + I  D+ KE + + +I+ T++ YGKL 
Sbjct: 26  LAREGAKIVVSDIDEEGGKKVVQQIKEDGGEAIFIKQDVAKEDEWKNVIETTLETYGKLH 85

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL--LESKGXXXXXXXXX 434
           +L N+AGI   GT+E+ +L  +  L++ N+   +  T   +  +   +  G         
Sbjct: 86  ILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGTKYGIKGMRKTDEGGSIINFSSIE 145

Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPK--GVRVNCVNPGVILTELQRRGGLSEEQ 608
           G+   P + AYN SK  V  FT+  AL  A +  G+R+N ++P  I T +      ++  
Sbjct: 146 GLIGDPNLPAYNASKGGVTIFTKSAALHCAKQGYGIRINSIHPAYIWTPMVENFLKAQGD 205

Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
                ++ +  H +G  G+PD++   + +LASD +  +TG
Sbjct: 206 VEEGKKQLESLHPIGHLGEPDDIGYGVVYLASDESKFMTG 245


>UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=8; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           JLS)
          Length = 256

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 61/218 (27%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260
           L++ GA + L GR  E L+  + D +      +++  D+TK    + ++  T+  +G+LD
Sbjct: 29  LAEHGADVVLAGRREEPLKATAADVEALGRRAIAVPTDVTKADQCQALVDATLGEFGRLD 88

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXG 437
           VL+NNAG  ET ++   +  ++  ++  N+ S +YL+  A  P + + KG          
Sbjct: 89  VLLNNAGGGETKSLMKWTDEEWHEVLELNLSSAWYLSRAAAKPMIAQGKGAIVNISSGAS 148

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           + + P    Y  +KA ++  T  +A     KGVRVNC+  G I T     G  ++ +   
Sbjct: 149 LLAMPQAPVYAAAKAGLNNLTGSMAAAWTRKGVRVNCIACGAIRTP----GLEADAKRQG 204

Query: 618 F-LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728
           F ++   +T+  GR  + DE+   + F ASD +S  +G
Sbjct: 205 FDIDMIGQTNGSGRIAEADEIGYGVLFFASDASSYCSG 242


>UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinobacter sp. ELB17
          Length = 264

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 72/220 (32%), Positives = 107/220 (48%), Gaps = 9/220 (4%)
 Frame = +3

Query: 96  GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
           GAQ+ +   +   L +      + A  L    D+  E+ +++++   +D +GK+D+L N 
Sbjct: 30  GAQVIMADTSELGLAETGNLMPEGAEYLRRLVDVADEAQVKELVSDAMDAFGKIDILCNI 89

Query: 276 AGIIETG-----TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437
           AGI  TG      IEN    ++D++++ N+     L     PH+   K G         G
Sbjct: 90  AGIASTGKGHPPVIENER-DEWDKVLSVNLIGTMLLIKHVAPHMQARKLGSIVNTASIAG 148

Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
           IRS  G  AY+ SKA V   T   A +L    +RVN V PG++ T + R    +   YA 
Sbjct: 149 IRSGAGGNAYSASKAGVINLTMTAACDLGDHNIRVNAVCPGLVETGMTR----AVFDYAR 204

Query: 618 FLERTKETHA---LGRPGKPDEVAATIAFLASDLASNITG 728
             E+  +  A   L R G P+E+AA I F ASD AS ITG
Sbjct: 205 THEKAHKLGARCELRRYGDPEEIAAAILFFASDDASYITG 244


>UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=2;
           Bacteria|Rep: Predicted short chain dehydrogenase -
           Bacillus sp. B14905
          Length = 251

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 67/217 (30%), Positives = 104/217 (47%), Gaps = 2/217 (0%)
 Frame = +3

Query: 84  LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 260
           ++K GA +++   N E  + + KD  + +  ++ + A+L +   + KII   ++ YGKLD
Sbjct: 26  MAKEGAIVTIVDLNAEAGEAMEKDLQQISPKSMFLQANLMERDQLPKIIDTVVEKYGKLD 85

Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440
           VLVNNA   +  TIE T+ A  D    T     +YL   A+PHL E++G         GI
Sbjct: 86  VLVNNAHAAKQVTIEETTQADLDLSFGTGFYPTFYLMQAALPHLKETQGNIINFASGAGI 145

Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
           +      AY  +K ++   +R  A E    G+ VN ++P      +Q       E Y   
Sbjct: 146 QGHETQAAYAAAKEAIRGISRVAANEWGRYGINVNIISPLADSPGVQAWAKAQPEYY--- 202

Query: 621 LERTKETHALGRPGKPDEVAATIA-FLASDLASNITG 728
            E  +    LGR G  ++    +A FLASD +  ITG
Sbjct: 203 -EAVRNKIPLGRFGHIEQDIGRVAVFLASDDSQYITG 238


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 705,861,424
Number of Sequences: 1657284
Number of extensions: 14114608
Number of successful extensions: 46276
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 40860
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42464
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 58853922985
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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