BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= bmmt10i09 (728 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p... 288 8e-77 UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 p... 250 3e-65 UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-... 198 1e-49 UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 196 6e-49 UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP000... 183 5e-45 UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1... 175 9e-43 UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chai... 174 2e-42 UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chai... 165 1e-39 UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR... 147 3e-34 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 137 3e-31 UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketor... 133 4e-30 UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep:... 130 5e-29 UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; ... 129 6e-29 UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 127 2e-28 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 127 2e-28 UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; ... 127 3e-28 UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Re... 126 4e-28 UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: A... 126 6e-28 UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR... 126 7e-28 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 124 2e-27 UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep... 123 5e-27 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 123 5e-27 UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR... 122 7e-27 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 122 9e-27 UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena... 122 1e-26 UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 121 2e-26 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 121 2e-26 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 120 3e-26 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 120 4e-26 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 120 5e-26 UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 119 8e-26 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 118 1e-25 UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ... 117 3e-25 UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR... 117 3e-25 UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR... 116 4e-25 UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR... 116 4e-25 UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;... 116 4e-25 UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;... 116 6e-25 UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ... 116 6e-25 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24 UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR... 115 1e-24 UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; ... 115 1e-24 UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR... 114 2e-24 UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero... 114 2e-24 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 113 3e-24 UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 113 4e-24 UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh... 113 6e-24 UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 112 7e-24 UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductas... 112 7e-24 UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 112 1e-23 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 112 1e-23 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 112 1e-23 UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=... 111 1e-23 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 111 1e-23 UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase fam... 111 1e-23 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 111 1e-23 UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23 UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain de... 111 2e-23 UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 111 2e-23 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 110 3e-23 UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR... 110 3e-23 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 110 4e-23 UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 110 4e-23 UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR... 109 5e-23 UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan... 109 5e-23 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 109 7e-23 UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR... 109 7e-23 UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|R... 109 9e-23 UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 109 9e-23 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23 UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; ... 109 9e-23 UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase fam... 109 9e-23 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 109 9e-23 UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 108 1e-22 UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 108 1e-22 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 108 1e-22 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 108 1e-22 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 108 2e-22 UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ... 108 2e-22 UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio bacte... 107 2e-22 UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 107 3e-22 UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22 UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR... 107 4e-22 UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 106 5e-22 UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR... 106 5e-22 UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR... 106 5e-22 UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOH... 106 6e-22 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 106 6e-22 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 106 6e-22 UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/M... 106 6e-22 UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/redu... 105 8e-22 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 105 8e-22 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 105 8e-22 UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22 UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 105 1e-21 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 105 1e-21 UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 105 1e-21 UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21 UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 105 1e-21 UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 105 1e-21 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21 UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21 UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR... 105 1e-21 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 104 2e-21 UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21 UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R... 104 2e-21 UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family memb... 104 2e-21 UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 104 3e-21 UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae... 104 3e-21 UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR... 104 3e-21 UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep:... 104 3e-21 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 104 3e-21 UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-su... 103 3e-21 UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrob... 103 3e-21 UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 103 3e-21 UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogena... 103 3e-21 UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 103 3e-21 UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenas... 103 4e-21 UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21 UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re... 103 4e-21 UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopire... 103 4e-21 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 103 4e-21 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 103 4e-21 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 103 4e-21 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 103 6e-21 UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya... 103 6e-21 UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 103 6e-21 UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21 UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;... 103 6e-21 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 102 8e-21 UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21 UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 102 8e-21 UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ... 102 8e-21 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 102 1e-20 UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteri... 102 1e-20 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20 UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Microm... 102 1e-20 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20 UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 101 1e-20 UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str... 101 1e-20 UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 101 1e-20 UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 101 1e-20 UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 101 2e-20 UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 101 2e-20 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 101 2e-20 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 101 2e-20 UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR... 101 2e-20 UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2; Pichi... 101 2e-20 UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 100 3e-20 UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20 UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 100 3e-20 UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20 UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20 UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR... 100 3e-20 UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20 UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20 UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha... 100 4e-20 UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20 UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20 UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular... 100 4e-20 UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 99 6e-20 UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6... 99 6e-20 UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Re... 99 6e-20 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 99 6e-20 UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 99 6e-20 UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 99 6e-20 UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR... 99 6e-20 UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 6e-20 UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reducta... 99 6e-20 UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reducta... 99 6e-20 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 99 6e-20 UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl... 100 7e-20 UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1... 100 7e-20 UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1; Thermob... 100 7e-20 UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 100 7e-20 UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain de... 100 7e-20 UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1... 100 7e-20 UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobact... 100 7e-20 UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 100 7e-20 UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR... 100 7e-20 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 100 7e-20 UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Ac... 99 1e-19 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 99 1e-19 UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 99 1e-19 UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder... 99 1e-19 UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|... 99 1e-19 UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_A4T6Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 99 1e-19 UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_A0GDY0 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 99 1e-19 UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb... 99 1e-19 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 98 2e-19 UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain dehydrogena... 98 2e-19 UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_Q3WHY3 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacte... 98 2e-19 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 98 2e-19 UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 98 2e-19 UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 98 2e-19 UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specifici... 98 2e-19 UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: G... 98 2e-19 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 98 2e-19 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 98 2e-19 UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 97 3e-19 UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 97 3e-19 UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|... 97 3e-19 UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 97 3e-19 UniRef50_A2W1T9 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A0XC03 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A0JX96 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_Q2UFW9 Cluster: Dehydrogenases with different specifici... 97 3e-19 UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 97 4e-19 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 97 4e-19 UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 97 4e-19 UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 97 4e-19 UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19 UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma p... 97 5e-19 UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19 UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholder... 97 5e-19 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 97 5e-19 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19 UniRef50_A4M3J4 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19 UniRef50_Q9PDC2 Cluster: Pteridine reductase 1; n=11; Xanthomona... 96 7e-19 UniRef50_Q39MZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 96 7e-19 UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier prot... 96 7e-19 UniRef50_A6GPQ6 Cluster: Short chain dehydrogenase; n=1; Limnoba... 96 7e-19 UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogena... 96 7e-19 UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:... 96 9e-19 UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 96 9e-19 UniRef50_Q983U4 Cluster: Putative dehydrogenase; n=1; Mesorhizob... 96 9e-19 UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_Q3WEN2 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_Q2C7C6 Cluster: Oxidoreductase, short-chain dehydrogena... 96 9e-19 UniRef50_Q1GHX9 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni... 96 9e-19 UniRef50_Q03RV5 Cluster: 3-oxoacyl-acyl carrier protein reductas... 96 9e-19 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_A5D4R4 Cluster: Dehydrogenases with different specifici... 96 9e-19 UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 96 9e-19 UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola... 96 9e-19 UniRef50_A1WWM8 Cluster: Short-chain dehydrogenase/reductase SDR... 96 9e-19 UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ... 96 9e-19 UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehy... 95 1e-18 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 95 1e-18 UniRef50_Q8YJQ0 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 95 1e-18 UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 95 1e-18 UniRef50_Q4FPW9 Cluster: Possible Short-chain dehydrogenase/redu... 95 1e-18 UniRef50_Q3IVH6 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ... 95 1e-18 UniRef50_Q2J6E1 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 95 1e-18 UniRef50_Q0SJP6 Cluster: Probable 3-oxoacyl-[acyl-carrier protei... 95 1e-18 UniRef50_Q0FYP2 Cluster: Probable oxidoreductase protein, short-... 95 1e-18 UniRef50_Q0FPS1 Cluster: Probable dehydrogenase; n=1; Roseovariu... 95 1e-18 UniRef50_A5VBH4 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_A5CY54 Cluster: Dehydrogenases with different specifici... 95 1e-18 UniRef50_A1SIL0 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q8YSW6 Cluster: Oxidoreductase; n=3; Nostocaceae|Rep: O... 95 2e-18 UniRef50_Q62E80 Cluster: Acetoacetyl-CoA reductase; n=60; Proteo... 95 2e-18 UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q6W1L9 Cluster: Short chain dehydrogenase; n=2; Rhizobi... 95 2e-18 UniRef50_Q3W9G7 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q3W2E5 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 95 2e-18 UniRef50_A5UX97 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein... 95 2e-18 UniRef50_A1VQU4 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo... 95 2e-18 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 95 2e-18 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 95 2e-18 UniRef50_Q9BY49 Cluster: Peroxisomal trans-2-enoyl-CoA reductase... 95 2e-18 UniRef50_Q8YHX9 Cluster: SHORT-CHAIN DEHYDROGENASE; n=10; Bacter... 95 2e-18 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 95 2e-18 UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 95 2e-18 UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 95 2e-18 UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reduc... 95 2e-18 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 95 2e-18 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q398J5 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q395K9 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q2S4K7 Cluster: Oxidoreductase, short chain dehydrogena... 95 2e-18 UniRef50_Q676G3 Cluster: Probable short-chain dehydrogenase; n=1... 95 2e-18 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 95 2e-18 UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q1ASH3 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q18YK8 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 95 2e-18 UniRef50_Q08XI3 Cluster: 2-(S)-hydroxypropyl-CoM dehydrogenase; ... 95 2e-18 UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_A5V529 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 95 2e-18 UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family memb... 95 2e-18 UniRef50_Q83BJ4 Cluster: Oxidoreductase, short chain dehydrogena... 94 3e-18 UniRef50_Q1NA92 Cluster: Gluconate 5-dehydrogenase; n=1; Sphingo... 94 3e-18 UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q12JI9 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogena... 94 3e-18 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena... 94 3e-18 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q8ZYG0 Cluster: Short chain dehydrogenase; n=2; Pyrobac... 94 3e-18 UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 94 3e-18 UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus eryth... 94 4e-18 UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 94 4e-18 UniRef50_Q1VSS0 Cluster: Gluconate 5-dehydrogenase, putative; n=... 94 4e-18 UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida... 94 4e-18 UniRef50_Q0K556 Cluster: Short chain dehydrogenase; n=1; Ralston... 94 4e-18 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_A5G1R2 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR... 94 4e-18 UniRef50_P52037 Cluster: Uncharacterized oxidoreductase ygfF; n=... 94 4e-18 UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductas... 93 5e-18 UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 93 5e-18 UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR... 93 5e-18 UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 93 5e-18 UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;... 93 5e-18 UniRef50_A5I7D8 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n... 93 5e-18 UniRef50_A3U1B5 Cluster: Putative short chain dehydrogenase; n=1... 93 5e-18 UniRef50_Q9URX0 Cluster: Short chain dehydrogenase; n=1; Schizos... 93 5e-18 UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 93 6e-18 UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena... 93 6e-18 UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;... 93 6e-18 UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena... 93 6e-18 UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain dehydrogena... 93 6e-18 UniRef50_Q2J935 Cluster: Short-chain dehydrogenase/reductase SDR... 93 6e-18 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 93 6e-18 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 93 6e-18 UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc... 93 6e-18 UniRef50_A5VE69 Cluster: Short-chain dehydrogenase/reductase SDR... 93 6e-18 UniRef50_A5V448 Cluster: Short-chain dehydrogenase/reductase SDR... 93 6e-18 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 93 6e-18 UniRef50_A3K6R9 Cluster: Short-chain dehydrogenase/reductase SDR... 93 6e-18 UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 93 6e-18 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 93 6e-18 UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like;... 93 6e-18 UniRef50_A7RYX9 Cluster: Predicted protein; n=1; Nematostella ve... 93 6e-18 UniRef50_Q9HT49 Cluster: Probable short-chain dehydrogenase; n=5... 93 8e-18 UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 93 8e-18 UniRef50_Q89FM8 Cluster: Dehydrogenase; n=1; Bradyrhizobium japo... 93 8e-18 UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 93 8e-18 UniRef50_Q5MPN9 Cluster: Hypothetical 3-oxoacyl-acyl carrier pro... 93 8e-18 UniRef50_Q1LDG6 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_Q128G0 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_A5V6V5 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 93 8e-18 UniRef50_A3VA26 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_A1UM67 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_A0VRG5 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_Q21929 Cluster: Probable L-xylulose reductase; n=3; Bil... 93 8e-18 UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 93 8e-18 UniRef50_UPI0000E252C4 Cluster: PREDICTED: similar to Dehydrogen... 92 1e-17 UniRef50_Q3WFB3 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 92 1e-17 UniRef50_A4W910 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A1SNX1 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A0GD21 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_Q0GJJ3 Cluster: 11-beta-hydroxysteroid dehydrogenase-li... 92 1e-17 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 92 1e-17 UniRef50_Q9RJU5 Cluster: Probable oxidoreductase; n=1; Streptomy... 92 1e-17 UniRef50_Q62GI3 Cluster: Oxidoreductase, short-chain dehydrogena... 92 1e-17 UniRef50_Q602S5 Cluster: Oxidoreductase, short chain dehydrogena... 92 1e-17 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 92 1e-17 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_Q2G822 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_Q0I7J4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 92 1e-17 UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 92 1e-17 UniRef50_A5EDQ3 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 92 1e-17 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 92 1e-17 UniRef50_A0V892 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 92 1e-17 UniRef50_A2TF13 Cluster: 11-beta short-chain dehydrogenase reduc... 92 1e-17 UniRef50_Q9KEP9 Cluster: Dehydrogenase/reductase family; n=12; B... 91 2e-17 UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogena... 91 2e-17 UniRef50_Q1RS55 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 91 2e-17 UniRef50_A4XEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta... 91 2e-17 UniRef50_A0LVM3 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 91 2e-17 UniRef50_Q9ANA1 Cluster: ID403; n=2; Proteobacteria|Rep: ID403 -... 91 3e-17 UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 91 3e-17 UniRef50_Q5LMF4 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 91 3e-17 UniRef50_Q3IVC8 Cluster: Short-chain alcohol dehydrogenases; n=2... 91 3e-17 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 91 3e-17 UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q2N2P3 Cluster: 3-oxoacyl-carrier-protein reductase; n=... 91 3e-17 UniRef50_Q1ARR8 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q0AT35 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17 UniRef50_A1UD00 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q0CF34 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17 UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogena... 91 3e-17 UniRef50_P50199 Cluster: Gluconate 5-dehydrogenase; n=35; Bacter... 91 3e-17 UniRef50_P80869 Cluster: Glucose 1-dehydrogenase 2; n=39; Bacill... 91 3e-17 UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al... 91 3e-17 UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 91 3e-17 UniRef50_Q53W85 Cluster: Oxidoreductase, short-chain dehydrogena... 91 3e-17 UniRef50_Q2CHI2 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q1NHB1 Cluster: Oxidoreductase; n=1; Sphingomonas sp. S... 91 3e-17 UniRef50_Q1M6N2 Cluster: Putative short-chain dehydrogenase/redu... 91 3e-17 UniRef50_Q08Z99 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 91 3e-17 UniRef50_A6EBP7 Cluster: Short chain dehydrogenase; n=1; Pedobac... 91 3e-17 UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 91 3e-17 UniRef50_A1R756 Cluster: Putative 3-oxoacyl-(Acyl carrier protei... 91 3e-17 UniRef50_Q8YDW1 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 90 4e-17 UniRef50_Q8R6S8 Cluster: Dehydrogenases with different specifici... 90 4e-17 UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 90 4e-17 UniRef50_A4FJJ0 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_A1SCT9 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_A0Z805 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 90 4e-17 UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=1... 90 4e-17 UniRef50_A2QKU0 Cluster: Contig An05c0050, complete genome; n=3;... 90 4e-17 UniRef50_Q9RWD9 Cluster: Oxidoreductase, short-chain dehydrogena... 90 6e-17 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 90 6e-17 UniRef50_Q8U673 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 90 6e-17 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 90 6e-17 UniRef50_Q28RW9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 90 6e-17 UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 90 6e-17 UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A6PKN4 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 90 6e-17 UniRef50_A3JX84 Cluster: Short chain dehydrogenase; n=5; Alphapr... 90 6e-17 UniRef50_A2TZE3 Cluster: Putative dehydrogenase; n=1; Polaribact... 90 6e-17 UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=... 90 6e-17 UniRef50_A7D7F1 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 89 8e-17 UniRef50_Q8UAP0 Cluster: Dehydrogenase; n=7; Bacteria|Rep: Dehyd... 89 8e-17 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 89 8e-17 UniRef50_Q7WPD3 Cluster: Probable short-chain dehydrogenase; n=1... 89 8e-17 UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;... 89 8e-17 UniRef50_Q39DX6 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 89 8e-17 UniRef50_Q0LZB7 Cluster: NAD-dependent epimerase/dehydratase:Sho... 89 8e-17 UniRef50_Q03ND1 Cluster: 3-oxoacyl-acyl carrier protein reductas... 89 8e-17 UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_A6W647 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 89 8e-17 UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 89 8e-17 UniRef50_A2RBM4 Cluster: Contig An19c0010, complete genome; n=6;... 89 8e-17 >UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p - Drosophila melanogaster (Fruit fly) Length = 269 Score = 288 bits (707), Expect = 8e-77 Identities = 147/241 (60%), Positives = 171/241 (70%), Gaps = 2/241 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--I 185 MNFAGKVV +K GA L+L GRNVENL+KV+ +C K + + + Sbjct: 14 MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALV 73 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365 D+ KE+D ++I +T+ YGKLDVLVNNAGIIETGTIE TSL QYDR+MNTN+R+IY+ Sbjct: 74 VGDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYH 133 Query: 366 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 LTMLA P L+++KG GIRSFPGVLAYNISK VDQFTRCVALELA KGVRVN Sbjct: 134 LTMLATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVN 193 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 CVNPGV +T L RGG+ E Y FLE +K THALGRPG EVAA IAFLASD AS T Sbjct: 194 CVNPGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFST 253 Query: 726 G 728 G Sbjct: 254 G 254 >UniRef50_UPI0000E48B21 Cluster: PREDICTED: similar to MGC79752 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC79752 protein - Strongylocentrotus purpuratus Length = 303 Score = 250 bits (612), Expect = 3e-65 Identities = 121/216 (56%), Positives = 160/216 (74%), Gaps = 2/216 (0%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 260 S LGA+L L GR NL + C + + L++T +L S + ++++ ++ YGKLD Sbjct: 73 SHLGARLVLAGRKEANLMRTKDSCMQTGNEEALTVTGELRDGSYRKHLVEQAMEEYGKLD 132 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 +LVNNAG+I G+IEN+SL YD +M+ NVRS+++LT LAVPHL+E+KG G+ Sbjct: 133 ILVNNAGVISLGSIENSSLEDYDTMMDVNVRSVFHLTSLAVPHLIETKGNIVNVSSVNGL 192 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 R+F GVL+Y +SKA++D FTRC ALELAPKGVRVN VNPGV +TELQ+RGGLS+E YA F Sbjct: 193 RAFAGVLSYCMSKAALDHFTRCTALELAPKGVRVNSVNPGVTITELQKRGGLSDEAYANF 252 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 LER+K THALGRPG+ E+A +IAFLASD +S ITG Sbjct: 253 LERSKMTHALGRPGEASEIAESIAFLASDASSFITG 288 >UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-like protein; n=3; Bilateria|Rep: U2 snRNP splicing factor small subunit-like protein - Schistosoma mansoni (Blood fluke) Length = 265 Score = 198 bits (482), Expect = 1e-49 Identities = 106/224 (47%), Positives = 141/224 (62%), Gaps = 10/224 (4%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAST----------LSITADLTKESDIEKIIKKT 236 +KLGA ++L R+ L++ + C + + L I ADL + +IEK + Sbjct: 27 AKLGACVALIARDKSRLEETRQACIQISHPDVYEKHKEPFLCIEADLAETCEIEKAYRLA 86 Query: 237 IDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 416 I+H+ +LD+LVNNAG + T E+ ++A+Y+ LM NV + LT LA+P L SKG Sbjct: 87 INHFHQLDILVNNAGCMIRDTAESFNVAEYEHLMKVNVTAAITLTNLAIPDLAASKGSIV 146 Query: 417 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596 G RSFPGV++Y ISKA++DQFTRC AL+LAPKG+RVN V P VI+TEL RR G+ Sbjct: 147 NVSSVCGKRSFPGVMSYCISKAALDQFTRCTALDLAPKGIRVNSVYPAVIVTELHRRSGM 206 Query: 597 SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 SE Y FL R ETHALGR G +EVA IAFL+S +S TG Sbjct: 207 SENDYEKFLSRANETHALGRTGTVEEVAQAIAFLSSSASSFTTG 250 >UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p - Drosophila melanogaster (Fruit fly) Length = 255 Score = 196 bits (477), Expect = 6e-49 Identities = 100/239 (41%), Positives = 147/239 (61%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 M+ + KVV L++ GA L+L GRNV NL+ K K + A Sbjct: 5 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSL-KGTQAEIVVA 63 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D+TK++D I+++T+ +G++DVLVNNAGI+ G + + + ++D ++NTN+R + LT Sbjct: 64 DVTKDADA--IVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLT 121 Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551 +PHLL++KG GIR F G L+Y +SKA++DQFT+ VALE+AP+GVRVN V Sbjct: 122 KAVLPHLLKTKGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSV 181 Query: 552 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 NPG ++T + R G+ +E+Y L+R +H +GR G EVA +AFLAS AS TG Sbjct: 182 NPGFVVTNIHRNIGIVDEEYNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTG 240 >UniRef50_UPI0000E499EA Cluster: PREDICTED: similar to ENSANGP00000021339; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000021339 - Strongylocentrotus purpuratus Length = 242 Score = 183 bits (445), Expect = 5e-45 Identities = 93/219 (42%), Positives = 139/219 (63%), Gaps = 5/219 (2%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSITADLTKESDIEKIIKKTIDHYGK 254 + LG +L+LTGRN+E LQ+V+ +C + L I AD E+D+++ ++TI + + Sbjct: 6 ASLGCRLALTGRNMETLQEVTNECIRRGLDKNKILMIQADFELEADVKRTAEETIQKFNQ 65 Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 434 +DVLVNNAG++ G++E SL +D++ NVR+ LT L P L+++KG Sbjct: 66 IDVLVNNAGVLTAGSVETVSLESFDKIFAVNVRAPLQLTQLLAPQLIKTKGTVVNVSSVV 125 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GLSEEQY 611 G S P L Y++SK ++D TR +A ELAP GVRVN VNPG I+T + +R G+++E+ Sbjct: 126 GKVSMPDFLIYSMSKTALDHMTRSIAEELAPHGVRVNAVNPGAIVTPIIKRSFGMTDEET 185 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A F E+ K HA+ R G DEV+ TIAF+AS+ +S TG Sbjct: 186 AQFFEKMKRNHAMRRTGTVDEVSRTIAFMASNDSSFTTG 224 >UniRef50_Q9NBB5 Cluster: 3-dehydroecdysone 3alpha-reductase; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3alpha-reductase - Spodoptera littoralis (Egyptian cotton leafworm) Length = 249 Score = 175 bits (426), Expect = 9e-43 Identities = 95/240 (39%), Positives = 142/240 (59%), Gaps = 3/240 (1%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITAD 194 FA KVV K GA ++ GRN L++V C + A+ L+I AD Sbjct: 2 FANKVVLVTGGSSGIGAATVEAFVKEGASVAFVGRNQAKLKEVESRCQQHGANILAIKAD 61 Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLT 371 ++K+ + + I+++T+D +GKLDVLVNNAGI+ ++ E T + +D MNTN+R + +T Sbjct: 62 VSKDEEAKIIVQQTVDKFGKLDVLVNNAGILRFASVLEPTLIQTFDETMNTNLRPVVLIT 121 Query: 372 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 LA+PHL+ +KG I PG+++Y++SKA++D FT+ ALELAP GVRVN Sbjct: 122 SLAIPHLIATKGSIVNVSSILSTIVRIPGIMSYSVSKAAMDHFTKLAALELAPSGVRVNS 181 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 VNPG +LT++ G S + LE T LG+ + +E+A I +LASD A ++TG Sbjct: 182 VNPGPVLTDIAAGSGFSPD----LLEDTGAHTPLGKAAQSEEIADMIVYLASDKAKSVTG 237 >UniRef50_UPI0000E47988 Cluster: PREDICTED: similar to short-chain dehydrogenase; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to short-chain dehydrogenase - Strongylocentrotus purpuratus Length = 269 Score = 174 bits (424), Expect = 2e-42 Identities = 103/242 (42%), Positives = 138/242 (57%), Gaps = 5/242 (2%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 185 F GKVV + GA L+L GR+ L+K ++DC L+I Sbjct: 4 FVGKVVLITGASSGIGAETAVHFAAEGAGLALVGRDEGRLEKTAQDCMAKGLAKDKVLTI 63 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN-TSLAQYDRLMNTNVRSIY 362 AD+ E D+++I++ TI ++G+LDVLVNNAG + + + T + +D L+ NVRS+ Sbjct: 64 KADMCVEEDVKRIVESTITYFGRLDVLVNNAGQAKLDLLRSETVMENFDDLLKLNVRSVV 123 Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542 LT LAVPHL+ SKG G R +YNI +A+ DQFTRC A++LAPKGVRV Sbjct: 124 QLTNLAVPHLITSKGSVVNVSSLAGKRVAHMSFSYNILRAATDQFTRCCAVDLAPKGVRV 183 Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722 N VNPG I T L G+ EQ E + H LGR G+P +VA+ I FLAS+ AS I Sbjct: 184 NAVNPGAIKTPLLTGFGIPAEQIE---EVCAKMHPLGRIGQPTDVASAIKFLASNAASFI 240 Query: 723 TG 728 TG Sbjct: 241 TG 242 >UniRef50_UPI0000E480C6 Cluster: PREDICTED: similar to short-chain dehydrogenase; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to short-chain dehydrogenase - Strongylocentrotus purpuratus Length = 250 Score = 165 bits (400), Expect = 1e-39 Identities = 89/218 (40%), Positives = 130/218 (59%), Gaps = 4/218 (1%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSITADLTKESDIEKIIKKTIDHYGK 254 +++G +L+LTGR+ E L+ V K C + + L I ADLT++ D+E+I KTI+ +G+ Sbjct: 24 AEIGCRLALTGRDAEKLKDVGKSCCERGLSEKEILVIAADLTEDEDLERIFSKTIEKFGR 83 Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 434 LD+L+NNAG G + + +D +M N+RS YL+ LA+P+L ESKG Sbjct: 84 LDILINNAGRPAKGRFHDLQMTFFDDVMRLNLRSAIYLSKLAIPYLKESKGCVVNMSSVA 143 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 + Y+ISK ++DQFT+ +A+EL P GVRVN +NPGVILT L R G S+ Q Sbjct: 144 SKTTCDYNPTYSISKVALDQFTKSLAVELGPYGVRVNSLNPGVILTPLYRNLGKSDAQVI 203 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + +K H +GR G DEV +L SD + +TG Sbjct: 204 TW---SKSMHPIGRHGTVDEVVKATEYLVSDASRCVTG 238 >UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Pasteurellaceae|Rep: Short-chain dehydrogenase/reductase SDR - Actinobacillus succinogenes 130Z Length = 248 Score = 147 bits (356), Expect = 3e-34 Identities = 82/215 (38%), Positives = 119/215 (55%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 ++K GA + + GRN L++ ++ + + AD+ K DI +++ + + +GKLD+ Sbjct: 26 MAKDGANVVIIGRNEATLEE---SAEQHENITYLVADVLKSEDIARVLTEIQEEFGKLDI 82 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443 +VNNAGI IEN +LA +DR NVR++ +T A+P+L SKG Sbjct: 83 VVNNAGIAPMTPIENINLADFDRTFALNVRAVIDVTAQAIPYLKASKGNIVNIISGLVHN 142 Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623 PG Y SKA+V TR A ELA G+RVNCV+ G T + G SEEQ A+ Sbjct: 143 PMPGNCIYTASKAAVLSLTRTWAKELAAYGIRVNCVSVGAANTSIHDALGFSEEQMNAYK 202 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + LGR G+PDE+A +AFLAS+ A +TG Sbjct: 203 QAVSSAVPLGRFGEPDEIAPIVAFLASEHARYVTG 237 >UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14; n=5; Caenorhabditis|Rep: Dehydrogenases, short chain protein 14 - Caenorhabditis elegans Length = 279 Score = 137 bits (331), Expect = 3e-31 Identities = 86/250 (34%), Positives = 136/250 (54%), Gaps = 13/250 (5%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFA----STLSI 185 F+GKV L++ GA++++TGRN + L++ ++ K LSI Sbjct: 4 FSGKVALVTGSSNGIGRATAVLLAQEGAKVTITGRNADRLEETRQEILKSGVPEDHVLSI 63 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIE-NTSLAQYDRLMNTNVR 353 DL E ++++ TI +G+LD+LVNNAG + G + + ++ YDR+M N+R Sbjct: 64 ATDLATEKGQDELVNSTIQKFGRLDILVNNAGAAFNDDQGRVGVDQDVSVYDRIMQINMR 123 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPK 530 S+ LT A HL+++KG G ++ P + Y +SKA++DQ+TR A++L Sbjct: 124 SVVTLTQKAKEHLVKAKGEVVNVSSIGAGPQAQPTFMYYAMSKAALDQYTRSAAIDLIQY 183 Query: 531 GVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701 GVRVN V+PG ++T G+ E+Y F+E KE G+ G+P ++A IAFLA Sbjct: 184 GVRVNSVSPGAVVTGFGEAMGMPADMHEKYGHFMESRKECIPCGKMGQPIDIANIIAFLA 243 Query: 702 S-DLASNITG 728 L+S I G Sbjct: 244 DRKLSSYIIG 253 >UniRef50_Q67RW6 Cluster: Ketoreductase; n=5; Bacteria|Rep: Ketoreductase - Symbiobacterium thermophilum Length = 241 Score = 133 bits (322), Expect = 4e-30 Identities = 79/214 (36%), Positives = 115/214 (53%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266 ++ GA++ +TGR E L++ +TAD+T SD +++++ +G++DV+ Sbjct: 19 ARRGAKVLITGRRPEPLRETEAAAPGIRG---VTADVTVASDARRVVEEAAKLWGRIDVV 75 Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 446 VNNAG+ +G E +L TNV L A+P L ES+G G ++ Sbjct: 76 VNNAGMFASGPFEKVGAETAAQLFATNVFGPINLVREALPWLKESRGAIINVSSTYGHKA 135 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626 V Y SKA++D TRC ALELAP G+RVN V PG T + R GL E+ A+ E Sbjct: 136 AANVAHYAASKAALDHLTRCWALELAPYGIRVNAVAPGPTETPILSRSGLPEDVVASIKE 195 Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 K LGR G+PD+VAA I LA+ + +TG Sbjct: 196 AEKRQIPLGRRGEPDDVAAWIVALAAPGSHWLTG 229 >UniRef50_A1C190 Cluster: Oxidoreductase; n=10; Streptomyces|Rep: Oxidoreductase - Streptomyces echinatus Length = 295 Score = 130 bits (313), Expect = 5e-29 Identities = 75/213 (35%), Positives = 118/213 (55%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ + GR L++ ++ ++ AD+T + ++ ++ +G++DVLVNN Sbjct: 74 GARVLVVGRTPGTLEETARH---HPGIRALPADITAPDGPDTVVSAALERFGRIDVLVNN 130 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX--GIRSF 449 A + GT++ A D + TN+R+ LT A+P L +S G G R++ Sbjct: 131 AALGIAGTLDTLDPADLDAQLATNLRAPMLLTRRALPALEKSSGTVVNLSTAGSLGRRAW 190 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 PG+ Y +K ++D TR A+ELAP+G+RV + PGVI T + R G SEEQYAAFL+ Sbjct: 191 PGMSVYGATKTALDFLTRTWAVELAPRGIRVVGLAPGVIDTGMATRNGASEEQYAAFLDG 250 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + GR G+P+E+A +A LA LA G Sbjct: 251 IRSRVPAGRVGRPEEIAWWVARLADPLAGYAHG 283 >UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; Rhizobium sp. NGR234|Rep: Putative uncharacterized protein - Rhizobium sp. (strain NGR234) Length = 244 Score = 129 bits (312), Expect = 6e-29 Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 1/184 (0%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359 SI+ D+T E + + I K + G+LD+L+NNAG+ E+G++E TSL Q+ RL++TN+ SI Sbjct: 49 SISLDVTDEGNWTRAISKVVSAAGRLDILINNAGVRESGSVEETSLEQWRRLIDTNLTSI 108 Query: 360 YYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 + AVP + ++ G GIR ++AY+ SK+ + T +AL+LA + Sbjct: 109 FLGCRAAVPAIRQAGGGAIVNVGSITGIRGTENMVAYSASKSGITSMTSSLALDLASDNI 168 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 RVN V P I T + S + A H +GR G+PDEVA+ IAFLASD +S Sbjct: 169 RVNAVCPAAIRTRMVTNWLNSSQDTDAAEAAVLAKHPIGRIGRPDEVASVIAFLASDDSS 228 Query: 717 NITG 728 +TG Sbjct: 229 FMTG 232 >UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Clostridium beijerinckii NCIMB 8052 Length = 246 Score = 127 bits (307), Expect = 2e-28 Identities = 77/240 (32%), Positives = 123/240 (51%), Gaps = 2/240 (0%) Frame = +3 Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSIT 188 N GKV LS LGA++ + N ++V ++ K ++I Sbjct: 3 NLEGKVAIITGASRGIGSAIARQLSALGAKVVVNYSNNAVKAEEVVEEITKSGEQAVAIK 62 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 AD++ D+EK+ +TI +G++D+L+NNAG+I + + + ++D+L N NV+ Y+ Sbjct: 63 ADVSNIKDVEKLFSETITKFGRVDILINNAGVILYKLLSDVTEEEFDKLFNINVKGTYFA 122 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 A+ H +E+ G FP Y +K +V+Q TR +A E PK + +N Sbjct: 123 CQQAMKH-MENNGRIINFSTSVVGSMFPTYSVYAATKGAVEQITRQLAKEFGPKKITINA 181 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 V PG I TEL G E+ +E ++ ++ GR G+PD++A TI FL SD A ITG Sbjct: 182 VAPGPINTELFNVGKTDEQ-----IEAIRQMNSFGRIGEPDDIANTIEFLVSDKAQWITG 236 >UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 269 Score = 127 bits (307), Expect = 2e-28 Identities = 73/242 (30%), Positives = 135/242 (55%), Gaps = 3/242 (1%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 ++ +GKV LS+ GA +++TG+ E L+KVS + +++ +I A Sbjct: 23 LSLSGKVALVTGGSRGIGFATAKVLSENGANVAITGKVQERLEKVSSE---ISNSFAIVA 79 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368 D+ K D++ IKK ++ +G+LD+LVNNAG+ + + +++ +++ N+ + + Sbjct: 80 DVRKTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRV 139 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALELAPKGVRV 542 T A+PHL ++ G G++++ G AY+ +KA++ T+C ALE + +RV Sbjct: 140 TKEAIPHLQKTSGSIINISSDAGLKAYQGFNADAYSATKAALIVLTKCWALEYSKDKIRV 199 Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722 NC+ PGV+ T++ + + ++ F+ H LGR G+P+EVA + + ASD A+ Sbjct: 200 NCICPGVVDTDM-TKPFVKTQKDRDFM---NAEHPLGRIGEPEEVAKAVLYFASDDAAWT 255 Query: 723 TG 728 TG Sbjct: 256 TG 257 >UniRef50_A5Z2G4 Cluster: Putative uncharacterized protein; n=1; Sarcoptes scabiei type suis|Rep: Putative uncharacterized protein - Sarcoptes scabiei type suis Length = 304 Score = 127 bits (306), Expect = 3e-28 Identities = 80/245 (32%), Positives = 127/245 (51%), Gaps = 7/245 (2%) Frame = +3 Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS----TLS 182 +F+GKV ++ GA++ +TGR+ L+KV+ + +K L Sbjct: 38 DFSGKVALVTGSSSGIGAAIALQFAQYGAKVCITGRDSNALEKVAGEIEKATGGKHRPLK 97 Query: 183 ITADLTKESDIE-KIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQ-YDRLMNTNVR 353 I L ++ + ++I +T++ +G+LD LVNNAG G + + +L YD++ + NVR Sbjct: 98 IIGGLVEDRQLPVRLINETVNEFGRLDFLVNNAGGSTAHGKLTDENLMDSYDKVFDLNVR 157 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533 S+ +L +A PHL ++KG I P L Y+ SKA++D T+C+A+E G Sbjct: 158 SVLHLCQVAKPHLEKTKGNIINISSIAAI--VPYSLIYSPSKAALDMMTKCLAIEYGDIG 215 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 VRVN +NPG + T R G+ + Y +R L DE+A +FLASD A Sbjct: 216 VRVNSINPGPVRTGFLRSMGMQMDNYDELYDRYSSNTLLNFVPYGDEIANLASFLASDDA 275 Query: 714 SNITG 728 N+TG Sbjct: 276 KNLTG 280 >UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Rep: Blr1409 protein - Bradyrhizobium japonicum Length = 266 Score = 126 bits (305), Expect = 4e-28 Identities = 77/241 (31%), Positives = 130/241 (53%), Gaps = 3/241 (1%) Frame = +3 Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 191 + GKV L++LGA++ ++ R + ++V+ + + I Sbjct: 16 DLTGKVAIVTGSSRGIGRSSAELLARLGAKVVVSSRKADACKEVADGINAAGGDAIVIPC 75 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 368 ++ +++++E +I HYGK+D+LV NA + G + + + +D++M +NV+S +L Sbjct: 76 NIARKAEVEALIAGATTHYGKIDILVCNAAVNPYYGPLLDITDEAFDKIMGSNVKSNIWL 135 Query: 369 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + LA+P + E G G+R + AY ISKA+ R +A E PKGVRVN Sbjct: 136 SALAIPQMAERGNGSVIIISSIGGLRGSTVIGAYGISKAADFALCRSLAGEWGPKGVRVN 195 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 C+ PG++ T+ R L E++ A L+R T L R G+PDE+A +A+LASD +S +T Sbjct: 196 CIAPGLVKTDFAR--ALWEDE--ALLKRRTATTPLRRIGEPDEIAGAVAYLASDASSFMT 251 Query: 726 G 728 G Sbjct: 252 G 252 >UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: AGR_C_2317p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 292 Score = 126 bits (304), Expect = 6e-28 Identities = 77/217 (35%), Positives = 111/217 (51%), Gaps = 1/217 (0%) Frame = +3 Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 FL + + +TGRN NL K A + +D+ K SD+E++ + K+D Sbjct: 67 FLEGGASTVYVTGRNSANLDAAVAKLGKGA--IGFVSDVAKLSDLEQLKSRLEADGRKVD 124 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 VLV NAGI E + T A YDR+ + NV+ ++Y +P +L G G Sbjct: 125 VLVANAGIAENNDLGETHEALYDRIFDINVKGVFYTVQTLLP-VLRDGGSIVLTGSIVGN 183 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GLSEEQYAA 617 + + AYN SKA+V F R A +L +G+RVN V+PGV T + G + +E+ A Sbjct: 184 KGMERLSAYNASKAAVRSFARSFANDLKGRGIRVNTVSPGVTRTPIMENGLKMDDEKIAG 243 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F K+ +GR PDE+A + FLAS AS ITG Sbjct: 244 FKAYLKDAAPIGRMADPDEIAEAVLFLASSKASYITG 280 >UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 255 Score = 126 bits (303), Expect = 7e-28 Identities = 72/217 (33%), Positives = 118/217 (54%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA L L RN ++ KV+ + K L++ D+ K DI+ ++ K I +G +D Sbjct: 30 LAEAGANLVLASRNEASMAKVASEVTSKGVQCLTVKTDMLKADDIQAMVDKGIAQFGTID 89 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437 +LVNNAGI N + +D +++TN++ + + + ++++K G G Sbjct: 90 ILVNNAGINLVKPFVNLTEEDWDSVVDTNLKGYFLCSQVVGREMIKNKNGCVINNASVFG 149 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 +R FP + +Y SK V Q TR +A+E A +RVNC+ PG I+TE+ +R E Sbjct: 150 LRGFPNIASYIASKGGVVQLTRGLAVEWARHNIRVNCIAPGYIVTEMAKR---DIETNPK 206 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 LE+ + R G+P EVA + FLAS+ +S +TG Sbjct: 207 ILEQNLLKIPMKRGGQPREVADVVVFLASEASSYMTG 243 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 124 bits (300), Expect = 2e-27 Identities = 82/247 (33%), Positives = 122/247 (49%), Gaps = 8/247 (3%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 188 M F GKV L++ GA + + R+ + + + + L++ Sbjct: 1 MEFQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVI 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 AD++ ESD +I T+ +G +D+LVNNAGI + GTIE+T+L + ++N N+ ++ + Sbjct: 61 ADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVFLV 120 Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + +P L G G+R+ G AY SK V TR +AL+ AP G+RVN Sbjct: 121 SRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDGAPDGIRVN 180 Query: 546 CVNPGVILTELQRRGGL------SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 CV PG+I T L R +E+ AF R LGR G P+EVAA I L S Sbjct: 181 CVCPGLIDTSLLRANAALVNTQRPDEELRAFARRV----PLGRLGTPEEVAAVILCLLSP 236 Query: 708 LASNITG 728 A +TG Sbjct: 237 TAGYLTG 243 >UniRef50_Q89K11 Cluster: Oxidoreductase; n=6; Proteobacteria|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 281 Score = 123 bits (296), Expect = 5e-27 Identities = 69/211 (32%), Positives = 116/211 (54%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ +TGRN E L +K+ A L++ AD T + E I++ + +GK D++ N Sbjct: 53 GAKVVITGRNKETLAAAAKELGPNA--LAVVADATDIAATEAAIRQGAEKFGKFDIVFAN 110 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AGI + + +L ++++++TN+ +++ A+PHL ++ + PG Sbjct: 111 AGIPGSTPLGAATLEVFEKVISTNLTGVFFTVQSALPHLNDNASIILNGSVI-SVLGIPG 169 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 AY +KA V R +A EL+P+G+RVN V PG I T + + E AF +R Sbjct: 170 YSAYGAAKAGVRAMARIMASELSPRGIRVNVVAPGAIRTPIWGAAIATPEAEKAFEKRIA 229 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 + LGR G+PD ++ T+ FLASD +++I G Sbjct: 230 LSTPLGRIGEPDHISKTVLFLASDDSAHIQG 260 >UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep: Bll5898 protein - Bradyrhizobium japonicum Length = 256 Score = 123 bits (296), Expect = 5e-27 Identities = 74/211 (35%), Positives = 108/211 (51%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA + L GR L +V + + AD+T +D+E ++ + +G++D+LVNN Sbjct: 31 GAIVVLNGRRESKLAEVGAELGTDRCMIR-PADVTIAADVESLVADAVRRFGRIDILVNN 89 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG + + Q+ L NV + Y+T A+PHL+ES G G+ G Sbjct: 90 AGTGALIDFLGSPIQQWRDLFAVNVDGVLYMTRAALPHLIESGGSIVNVSSLSGLGGDRG 149 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 + YN +K +V TR +ALE P+GVR+N V P + LT L EQY L + Sbjct: 150 LSFYNATKGAVSNLTRSLALEFGPRGVRINAVCPSLTLTHLTMP---ILEQYPELLAKLV 206 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 LGR + +EVA+ IAFLASD AS + G Sbjct: 207 GRIPLGRAAQSEEVASVIAFLASDDASFVNG 237 >UniRef50_Q1IK61 Cluster: Short-chain dehydrogenase/reductase SDR; n=56; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 252 Score = 122 bits (295), Expect = 7e-27 Identities = 76/211 (36%), Positives = 113/211 (53%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA + LTGR L + + S ++I D + SD+EKI+ + + GKLD+L N Sbjct: 33 GAFVFLTGRREPELLAAANELGP--SAIAIRTDSSLISDVEKILARIRETKGKLDILFAN 90 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AGI E + + +D++ +TNV+ I +L A+P L+ S I+ P Sbjct: 91 AGIGEFLPLGVITEEHFDKIFSTNVKGIVFLVQKALP-LMPSGSSIVLNASIASIKGMPA 149 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 Y+ SKA++ F R +L + +RVN V+PGVI T GLS+++ FL+ Sbjct: 150 FSIYSASKAALRSFARSWTTDLRRQQIRVNAVSPGVISTPGYDGLGLSKQEMETFLKTNA 209 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 ET LGR G PDEVA + FL+SD +S I+G Sbjct: 210 ETIPLGRVGTPDEVAKAVVFLSSDESSYISG 240 >UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succiniciproducens MBEL55E|Rep: FabG protein - Mannheimia succiniciproducens (strain MBEL55E) Length = 248 Score = 122 bits (294), Expect = 9e-27 Identities = 73/215 (33%), Positives = 115/215 (53%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L++ GA++ + GR + LQ+ + A + AD+ K+ D++KI+++ YG LD+ Sbjct: 26 LAQEGAKVLVVGRTEKTLQETTALHPNIAYAV---ADIEKDDDVQKIVQQLNQKYGGLDI 82 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443 L+NNAG I + +YD++ NVR++ LT+ +P L KG Sbjct: 83 LINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLTLQCLPMLKARKGNIINMSSAICRN 142 Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623 P + Y +KA+V+ FT+ A EL GVRVN ++ G I T + + LS + + Sbjct: 143 HLPNMSMYAGTKAAVEIFTKIWAKELGADGVRVNSISVGPIETPIYDKTDLSNDGIQDHI 202 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +R ++T LG GK ++VA AFLASD A ITG Sbjct: 203 DRIRKTIPLGAFGKSEDVANVTAFLASDEARFITG 237 >UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=4; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Psychroflexus torquis ATCC 700755 Length = 269 Score = 122 bits (293), Expect = 1e-26 Identities = 69/211 (32%), Positives = 109/211 (51%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA + +TGR+ E + K S++ I AD+ S I+ ++ + +GK+DVL N Sbjct: 48 GATVVITGRDSEKVAKASQEL----GVKGIVADVKSLSAIDDLVAQVKSDFGKVDVLFVN 103 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AGI + + S +D M+ N + ++ T +P +L P Sbjct: 104 AGIFQPAPVGQISEEMFDHQMSINFKGAFFTTEKFLP-ILNDGASVINLSSVNAYTGMPN 162 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 Y SKA+++ +TR A ELAP+ +R+N VNPG + T + + G+ EEQ F E + Sbjct: 163 TAVYAASKAALNAYTRTAATELAPRKIRINSVNPGPVSTPIYGKTGMEEEQLNGFAEAMQ 222 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 L R G+P+++A ++FLASD AS ITG Sbjct: 223 NRIPLKRFGQPEDIAKLVSFLASDDASFITG 253 >UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative 3-oxoacyl-[acyl-carrier protein] reductase - Arthrobacter aurescens (strain TC1) Length = 261 Score = 121 bits (292), Expect = 2e-26 Identities = 73/185 (39%), Positives = 101/185 (54%) Frame = +3 Query: 174 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 353 TL + AD+ IE II ++++ G LDVLVNNAGI TG TS + +M NV Sbjct: 60 TLKV-ADVGDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVD 118 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533 ++Y T A+PHL++S+G GI + AY+ SK +V FTR VA++ A +G Sbjct: 119 GLFYATRAALPHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVAVDYAQRG 178 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 VR N V PG +LT L ++ + + A E + LGR P+E+A FLAS A Sbjct: 179 VRCNAVAPGPVLTPLLQK---NLDSTAGLKEAFGRSIPLGRIAAPEEIAPAFTFLASSDA 235 Query: 714 SNITG 728 S I G Sbjct: 236 SYING 240 >UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 121 bits (292), Expect = 2e-26 Identities = 79/225 (35%), Positives = 123/225 (54%), Gaps = 13/225 (5%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC----DKFASTLSITADLTKESDIEKIIKKTIDHYG 251 L+ GA++++TGRN E L++ + L + D+T+ES E +IK T+D +G Sbjct: 26 LASEGAKVTVTGRNAERLEETKNILLGAGVPEGNVLVVVGDITQESVQENLIKSTLDKFG 85 Query: 252 KLDVLVNNAGI----IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXX 419 K+D+LVNNAG + + N S+ Y + NV+S+ +T A PHL +++G Sbjct: 86 KIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQSVIEMTQKARPHLAKTQGEIVN 145 Query: 420 XXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR-RGG 593 G + Y+I+KA++DQ+TR A++L P+G+RVN V+PG + T G Sbjct: 146 ISSIGAGPAAQVASPYYSIAKAALDQYTRTAAIDLVPEGIRVNSVSPGAVSTGFSAVSRG 205 Query: 594 LSEEQYAAF---LERTKETHALGRPGKPDEVAATIAFLASDLASN 719 L+EE+ AF L +E G P+++A IAFLA ASN Sbjct: 206 LTEEKSKAFYDYLGAQRECIPRGFCAVPEDIAKVIAFLADRNASN 250 >UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 249 Score = 120 bits (290), Expect = 3e-26 Identities = 75/215 (34%), Positives = 113/215 (52%), Gaps = 4/215 (1%) Frame = +3 Query: 96 GAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 G ++ ++GRN E + V++ + + I AD+T E D+ ++ KT++ +G+LDV V Sbjct: 30 GGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRADVTVEDDVRNLVAKTVEAFGRLDVFVA 89 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF- 449 N+G+ G ++DR+++ N++ I+ AV +L+ +G I SF Sbjct: 90 NSGVGSLGDPHEVETEEWDRVLDVNLKGIFLCDKYAVQQMLK-QGQGGAIVNTGSIHSFV 148 Query: 450 --PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623 GV AY +K V TR + A +G+R N V PG I T L L E Y Sbjct: 149 AKQGVTAYGAAKGGVAMLTRTLGTSYAAQGIRANFVAPGYIDTPL--LAALPREAY---- 202 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E K+ H +GR G+P EVA + FLASD ASNITG Sbjct: 203 EELKKLHPIGRLGRPMEVAKAVTFLASDDASNITG 237 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 120 bits (289), Expect = 4e-26 Identities = 72/215 (33%), Positives = 116/215 (53%), Gaps = 4/215 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ L RN+E L+ K+ ST ++T DL ES +++ + +D YGK+D+LVNN Sbjct: 29 GAKVILIARNLEGLENTRKEIGNEDSTAAMTCDLVDESQTLQVVNQIMDTYGKIDILVNN 88 Query: 276 AGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 449 AG I ++ +L+N N+ ++ +T + + + K G R+ Sbjct: 89 AGAINDPIHFHEMQNSEIQKLINVNLLGVFNMTKAVLTKMADVKSGSIVNIGSISSERAI 148 Query: 450 PGV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623 P V Y+ +KA++ FT+ +A+E A + +R NCVNPG+I + L + Q L Sbjct: 149 PRVHLAVYSATKAAIPMFTKSIAVEYARRNIRCNCVNPGII-NSGSIKPYLDDPQARKVL 207 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E E L R G+P++VA +A+LASD AS +TG Sbjct: 208 E---ERLPLARVGEPEDVANAVAYLASDEASWVTG 239 >UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase precursor; n=3; Cyanobacteria|Rep: NAD-dependent epimerase/dehydratase precursor - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 251 Score = 120 bits (288), Expect = 5e-26 Identities = 68/217 (31%), Positives = 118/217 (54%), Gaps = 3/217 (1%) Frame = +3 Query: 87 SKLGAQLSLTGRNV-ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 +K A++ + GR + E + V + + +D+TKE+D++ ++ K + +G+LD+ Sbjct: 26 AKQQAKVVVVGRRIDEGEETVRLIQEAGGEAFFVQSDVTKEADVKAMVDKAVGVFGRLDI 85 Query: 264 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 437 NNAG++ E ++ + A+YDR+MN NV+ ++ + +L + G G Sbjct: 86 AFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLSMKYEIAQMLKQGSGAIVNTSSGAG 145 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 + + PGV Y SK +V T+ AL+ A G+R+N V PG I T++ +++ A Sbjct: 146 VVALPGVPLYTASKHAVVGLTKAAALQYAKAGIRINAVAPGSIETDMFEAATGGQDEVKA 205 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ H +GR G P EVA + FL+SD+AS ITG Sbjct: 206 YI---TGLHPIGRIGTPLEVANAVLFLSSDIASFITG 239 >UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) reductase precursor; n=1; Rhodopseudomonas palustris|Rep: Putative 3-oxoacyl-(Acyl carrier ptn) reductase precursor - Rhodopseudomonas palustris Length = 262 Score = 119 bits (286), Expect = 8e-26 Identities = 79/240 (32%), Positives = 118/240 (49%), Gaps = 1/240 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 188 M F GKV L++ GA + L+ + + L + ++ A +S + Sbjct: 1 MRFNGKVAVVTAAASGIGAATAARLAREGAYVYLSDIDQDALGRQAESLVDVAERISTVV 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 AD+T + +I G+LD+L+NNAG+ G I + + R+ V SI++ Sbjct: 61 ADVTVPEQVSALIDGAARERGRLDILINNAGMGAFGRITEVTPEAWHRVFGICVDSIFHA 120 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 + A+PHL++++G G+ G AYN +K +V TR +AL+ + G+RVN Sbjct: 121 SRAAIPHLIKARGTIVNTASISGLFGDYGFAAYNAAKGAVINLTRNMALDYSRDGLRVNA 180 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 V PG+I T L L AA + LGR G P+EVA IAFLASD AS ITG Sbjct: 181 VCPGLIATPL----SLKLRDNAAVMAEYDRLIPLGRAGSPEEVAGAIAFLASDDASYITG 236 >UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Erythrobacter sp. NAP1 Length = 267 Score = 118 bits (285), Expect = 1e-25 Identities = 76/241 (31%), Positives = 120/241 (49%), Gaps = 4/241 (1%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADL 197 FAGK V GA + + RN E KV+ D TL+ D+ Sbjct: 7 FAGKTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADTLDA-DRTLTCPGDV 65 Query: 198 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 377 + +I+ KT++ +G LD LVNNAG+ + + T + DR+++ NV+ + YL Sbjct: 66 SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSMLHKTDDEEIDRIIDINVKGVIYLCRA 125 Query: 378 AVPHLLESK----GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 A+PHL +S+ G GI + YN SK ++ TR +A ++ G+RVN Sbjct: 126 AIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMGIRVN 185 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 +NP + +++ G L+ + A LE +GR G+P+++AA AFLAS+ A+ IT Sbjct: 186 AINPSITRSDMV-DGILAND---ALLEAFMRRVPMGRIGEPEDIAAACAFLASEDAAFIT 241 Query: 726 G 728 G Sbjct: 242 G 242 >UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; Zymomonas mobilis|Rep: Putative uncharacterized protein - Zymomonas mobilis Length = 254 Score = 117 bits (282), Expect = 3e-25 Identities = 74/247 (29%), Positives = 129/247 (52%), Gaps = 6/247 (2%) Frame = +3 Query: 6 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLS 182 V+ +++GKV +K A +++ GR+ N+Q+ + + ++ Sbjct: 3 VSFDYSGKVALVTGAGTGIGRETALAFAKAKAYVAIIGRSENNIQETLRLVTEMGGQAIA 62 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSL--AQYDRLMNTNVRS 356 I AD+++E I+ I+KT++ +GKLD NNAG IE I + ++DR+++TN+ Sbjct: 63 IQADVSQEDSIKAAIEKTVETFGKLDFAFNNAG-IEHKAIPAADIPSEEWDRIISTNLNG 121 Query: 357 IYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533 +++ +P +L+S G G++ FPG AY SK + ++ AL+ A + Sbjct: 122 VFFSMKHEIPAMLKSGSGSIVNTASGAGVKGFPGNGAYCASKFGLIGLSKAAALDYAKQH 181 Query: 534 VRVNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 +R+N V PG+I T + +R GG E + A + +GR G P E+A T+ +L SD Sbjct: 182 LRINVVAPGIIETPMMQRFTGGTEEGRETAIAQ-----EPVGRAGHPKEIAGTVLWLCSD 236 Query: 708 LASNITG 728 LA+ TG Sbjct: 237 LAAFTTG 243 >UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rhodobacteraceae|Rep: Short-chain dehydrogenase/reductase SDR - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 259 Score = 117 bits (281), Expect = 3e-25 Identities = 64/183 (34%), Positives = 98/183 (53%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359 +I AD + + + +D G+LDVLVNNAG+++ +E +LA ++R + N+ + Sbjct: 46 AIAADFADADAPARAVAEAVDRAGRLDVLVNNAGVMQEARVEEMALADWERTIRVNLTAP 105 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 + A+PHL +G G+ + P AY SKA + TR VA++ +G+R Sbjct: 106 FLAIRAALPHLRAVRGAIVNVGSIEGLGANPRHAAYCASKAGLHGLTRAVAVDHGAEGIR 165 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 N V PG I TEL + AF H +GR G+P+EVAA +A+LASD A+ Sbjct: 166 CNAVAPGWIETELNEAFVEAMPDPEAFRRGIGRIHPVGRTGQPEEVAALVAWLASDEAAF 225 Query: 720 ITG 728 +TG Sbjct: 226 VTG 228 >UniRef50_Q28Q26 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Jannaschia sp. CCS1|Rep: Short-chain dehydrogenase/reductase SDR - Jannaschia sp. (strain CCS1) Length = 254 Score = 116 bits (280), Expect = 4e-25 Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 3/204 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA++++TGR E L+ V+ + +I A D++ E D ++I + H G L L N Sbjct: 30 GAKVTITGRRAEKLEDVA---GAIGPSCAIAAGDVSIEEDRRRMIDTAVAHGGGLQGLFN 86 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452 NAG + G I + + +MN NV + LT LA PHL E G R+FP Sbjct: 87 NAGNMLRGPITDLAAEDILEVMNVNVVAGMRLTGLAAPHLEEHGGAVVFVGSGHTRRAFP 146 Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL--SEEQYAAFLE 626 G Y SK +V+ + +A EL PKG+RVNC+ PG + TE+ R G+ S E L Sbjct: 147 GASPYAASKGAVEVLAQVLAAELGPKGIRVNCIVPGAVPTEINVRAGIAASFEDNKVRLN 206 Query: 627 RTKETHALGRPGKPDEVAATIAFL 698 + H LGR G P E+A + L Sbjct: 207 SMVDDHPLGRIGTPQEIAEAVDHL 230 >UniRef50_A6PH85 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella sediminis HAW-EB3|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sediminis HAW-EB3 Length = 245 Score = 116 bits (280), Expect = 4e-25 Identities = 72/216 (33%), Positives = 112/216 (51%) Frame = +3 Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 F++K GA + +TGR L++ S++ I D++K+ +I+++TI +G+LD Sbjct: 26 FIAK-GATVVITGRRQSVLEETSQELGP--QVYPIVGDVSKKGGPARIVEETISKFGRLD 82 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 VLVNNAG + G + TS + + TNV ++ L A HL SKG Sbjct: 83 VLVNNAGTGKMGPLSETSDEDIESIYRTNVFALLALVREATVHLANSKGAVVNISSVAAQ 142 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 P V AY SKA+V+ TR +A EL P G+RVN V PG+ T++ +EE Sbjct: 143 GMMPAVAAYASSKAAVEHATRLLAAELGPMGIRVNAVAPGLTNTDIAADVKSNEEMLGMI 202 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + +T +GR G+P ++A + ++ A ITG Sbjct: 203 IAQT----PMGRLGEPKDIANVVLLMSGSGAGWITG 234 >UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15; n=4; Caenorhabditis|Rep: Dehydrogenases, short chain protein 15 - Caenorhabditis elegans Length = 278 Score = 116 bits (280), Expect = 4e-25 Identities = 73/223 (32%), Positives = 119/223 (53%), Gaps = 12/223 (5%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS----ITADLTKESDIEKIIKKTIDHYG 251 L++ GA++++TGR+ E +Q+ + K + + DL + +++IK T+ +G Sbjct: 26 LAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIVLGDLNESECQDELIKSTLSRFG 85 Query: 252 KLDVLVNNAGII---ETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXX 419 K+D+L+NNAG +G I ++ +D +M N+RS+ L PHL+ SKG Sbjct: 86 KIDILINNAGAAFADPSGKIGSEAAIGIFDDMMKLNLRSVVELVKKCRPHLIASKGEIVN 145 Query: 420 XXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596 G + + Y I KA +DQ TR +ALEL P VRVN V+PG+I T G+ Sbjct: 146 VSSIAAGPQPYIYYTYYGICKAGLDQLTRSLALELIPFDVRVNSVSPGLISTNFLGAVGM 205 Query: 597 SEE---QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 ++ + + ++ GR GKP+E+A+ IAFLA +S Sbjct: 206 GDDVVKKTEEYYSTHRDCIPAGRTGKPEEIASLIAFLADRKSS 248 >UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1; Thermobifida fusca YX|Rep: Short-chain alcohol dehydrogenase - Thermobifida fusca (strain YX) Length = 267 Score = 116 bits (279), Expect = 6e-25 Identities = 65/217 (29%), Positives = 113/217 (52%), Gaps = 6/217 (2%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA + RN + + D T L++TAD++ +D E++ T++H+G++D++ Sbjct: 33 GASVVCVDRNADAAHSAADDIAAAGGTALALTADVSSAADAERMTTTTLEHFGRIDIVFA 92 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 449 NAGI +G T+ ++DR++ N++ ++ + A+PH++E + G G+ Sbjct: 93 NAGIPGSGDAHTTTEEEWDRVIAINLKGVWLTSKYALPHMVERRSGVITNQASVGGLIGI 152 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL----QRRGGLSEEQYAA 617 PG+ Y +K V TR +A AP +RVN + PG + T L +++ GL+ Sbjct: 153 PGIFPYAAAKGGVISMTRQMAAAYAPHNIRVNAICPGGVYTPLVELSRQKRGLTASSVEE 212 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + LGR G +E+A+ FLASD A+ ITG Sbjct: 213 ANAIAARNYPLGRLGTVEEIASLALFLASDEAAWITG 249 >UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; Frankia|Rep: Putative dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 295 Score = 116 bits (279), Expect = 6e-25 Identities = 70/213 (32%), Positives = 109/213 (51%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++++ GR+ + V + + I AD+T ++ +I+ T+DH+G LD+L Sbjct: 75 GARVAVVGRDKAKMDAVVESLAPLGEIIGIQADVTVVAEAARIVSATVDHFGGLDILATV 134 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSF 449 AG+ E + + + A YD + NV+ Y+ A HL++ +G G+R+F Sbjct: 135 AGVFEGAPLLDATEADYDIQFDLNVKGTYFCAQAAARHLVDQGRRGKIITVGSVAGLRAF 194 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 PGV Y +KA+V T+ +A ELAP G+ VNCV PG I ++ LS A E Sbjct: 195 PGVSVYGATKAAVGFLTQVLAGELAPHGINVNCVVPGSI--DMPTNKLLSPPGAA---EA 249 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + R G P +VAA +LASD A + G Sbjct: 250 SAAGTPARRNGLPVDVAAAAVYLASDSADFVHG 282 >UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 271 Score = 115 bits (277), Expect = 1e-24 Identities = 60/179 (33%), Positives = 94/179 (52%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D++K D+E+ + I + ++D+LV+NAGI G + T +DR++ N++ + ++ Sbjct: 64 DVSKSKDVEQAVGDVITKHSQIDILVSNAGIQYYGDVITTPEDDWDRVIGVNLKGCFLIS 123 Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551 VPH++ + G + AY SK +V R +AL+ A KG+RVNCV Sbjct: 124 KFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMALDYAHKGIRVNCV 183 Query: 552 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 PG I T + + + HALGR GKPDEVA + +LAS ++S ITG Sbjct: 184 CPGTIDTPMLHWAASLSPDPESVIRTCDRMHALGRIGKPDEVADAVLYLASPMSSFITG 242 >UniRef50_A1UII7 Cluster: Short-chain dehydrogenase/reductase SDR; n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 251 Score = 115 bits (277), Expect = 1e-24 Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 GA ++ T G +V + KV D + L I AD + I + +T+ G LD+LV Sbjct: 35 GAAVAFTYGSSVSDADKVVVDVSRGGGRVLPIRADSSDAGQIASAVDETVTRLGGLDILV 94 Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449 NNAG+ G +E+ L Q+DRL+ NVR ++ AVPHL + Sbjct: 95 NNAGVAHLGAVESFPLDQFDRLVAVNVRGVFVAIQCAVPHLGDGGRIINIGSVNADRVPS 154 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 PG+ Y ++KA+V TR +A EL P+G+ VN V PG I T++ G F + Sbjct: 155 PGLSVYAMTKAAVAGLTRGLARELGPRGITVNTVAPGPIATDMNPAEG-------EFADA 207 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +E A+G G P +VA ++LA A +TG Sbjct: 208 AREIIAVGHYGNPTDVAGVASYLAGPDAGYVTG 240 >UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 402 Score = 115 bits (276), Expect = 1e-24 Identities = 80/250 (32%), Positives = 120/250 (48%), Gaps = 13/250 (5%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENL----QKVSKDCDKFASTLSI 185 F+GKV ++ GA++++TGRN E L Q + K + L+I Sbjct: 126 FSGKVALVTGSSNGIGRAAALLFAQQGAKVTITGRNAERLEETRQAILKSGVPAENVLAI 185 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ----YDRLMNTNVR 353 ADL + +I T+ +G+LD+LVNNAG + Q +D+ N+R Sbjct: 186 AADLATDQGQTDLINGTLQKFGRLDILVNNAGAAVNDPQGRMGIDQQIEDFDKTFQINMR 245 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPK 530 S+ L A HL+++KG G + P ++ Y +SKA++DQFTR A+ L Sbjct: 246 SVVTLVQKAKEHLIKTKGEIINVSSIGGGPHAQPDMMYYGMSKAALDQFTRSTAITLIQH 305 Query: 531 GVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701 GVRVN V+PG + T G + E+ + E KE G +P E+A IAFLA Sbjct: 306 GVRVNSVSPGGVYTGFGEAMGFPPGALEKIMKYFESHKECVPCGHMAQPIEIAQVIAFLA 365 Query: 702 S-DLASNITG 728 ++S I G Sbjct: 366 DRTMSSYIIG 375 Score = 64.1 bits (149), Expect = 3e-09 Identities = 39/95 (41%), Positives = 54/95 (56%), Gaps = 4/95 (4%) Frame = +3 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL---SEEQYAAFLE 626 ++ Y +SKA++DQFTR A+ L GVRVN V+PGV+ T + G + E+ F E Sbjct: 1 MMYYGMSKAALDQFTRSTAITLIQHGVRVNSVSPGVVYTGIGEAMGFPPGAFEKTMKFYE 60 Query: 627 RTKETHALGRPGKPDEVAATIAFLAS-DLASNITG 728 KE G +P E+A IAFLA ++S I G Sbjct: 61 SHKECVPCGHMAQPVEIAQVIAFLADRTMSSYIIG 95 >UniRef50_A3H8L6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 283 Score = 114 bits (275), Expect = 2e-24 Identities = 75/241 (31%), Positives = 122/241 (50%), Gaps = 6/241 (2%) Frame = +3 Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS---TLSITAD 194 GKVV ++G+++ + R+ + +Q V K + + S + + D Sbjct: 16 GKVVIVTGSTRGIGYEIVKLFKEMGSRVVVNARSADEVQTVVKKLNDYVSDGEAIGVAGD 75 Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 374 ++K D EKI+ +T+D YGK+DVLVNNAGI N S+ ++R + ++ S +Y++ Sbjct: 76 VSKYEDCEKIVNETVDKYGKIDVLVNNAGINMIRDSLNLSIDDWERTLRIDLFSAFYMSQ 135 Query: 375 LAVPHLL--ESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 L ++ + KG G I + P AY +KA + TR +A+E AP G+RVN Sbjct: 136 LVARTMVAKKVKGSIVNIASMVGPIVALPKRAAYAAAKAGLVGLTRVLAVEWAPLGIRVN 195 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 + PG I + Q ++ +Y + + +GR G EVA FLAS+LAS +T Sbjct: 196 AIAPGYIWSSAQ-EVNIARGEYTR--QDIEGRVPMGRYGDAREVAYVAVFLASELASYVT 252 Query: 726 G 728 G Sbjct: 253 G 253 >UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bacteroidetes|Rep: Short chain dehydrogenase - Algoriphagus sp. PR1 Length = 252 Score = 114 bits (274), Expect = 2e-24 Identities = 67/216 (31%), Positives = 117/216 (54%), Gaps = 2/216 (0%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 263 S+ GA L L+GRN EN ++ + ++ + + D+ E ++K I ++GKLD+ Sbjct: 26 SEEGAFLILSGRNQENGIELERSLNEAGGKAVFVKGDVGIIETNEALVKAAISNFGKLDI 85 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGI 440 +V NAG + G++ SLA++ MNTN ++++L+ A+P +++S G Sbjct: 86 VVTNAGKLGLGSVTEISLAEWQETMNTNFNAVFFLSRFAIPEMIKSGGGTILANSSIAAF 145 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 +SFP AY SKA++ + +A++ P +RVN + PG + T L + + Sbjct: 146 KSFPNHAAYCASKAALVALVKEMAVDYGP-NIRVNTMCPGPVDTPLIWDSAKAFDNPDTI 204 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ T + + R GKP+++A+ FL SD AS ITG Sbjct: 205 VQETAKNTLMNRLGKPEDIASLALFLVSDEASWITG 240 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 113 bits (273), Expect = 3e-24 Identities = 65/187 (34%), Positives = 105/187 (56%), Gaps = 5/187 (2%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + D+T E+ + ++ + +G LDVL+NNAGI I L+ +++++ N+ ++ Sbjct: 57 VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 116 Query: 363 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 ++ A+ H+L + KG G+ ++P + AYN SK V Q T+ +A++ A +R Sbjct: 117 LMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 176 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFLASD 707 VNCV PG+I T L + L E LE K+ A L R GKP+E+A + FLASD Sbjct: 177 VNCVCPGIIDTPLNEKSFL--ENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASD 234 Query: 708 LASNITG 728 L+S +TG Sbjct: 235 LSSYMTG 241 >UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 258 Score = 113 bits (272), Expect = 4e-24 Identities = 66/216 (30%), Positives = 115/216 (53%), Gaps = 5/216 (2%) Frame = +3 Query: 96 GAQ-LSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 GA+ L + GR ++ + C + A+ +++ D+T+E D+ +++ ++ G+LDV Sbjct: 37 GAEALIIAGRREAEIEATAAACREIGAAAIALKTDITREDDVARLVGIAVERCGRLDVAF 96 Query: 270 NNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIR 443 NNAG E +E YD + +TNVR+++ +P +L + +G G+R Sbjct: 97 NNAGFQERRAPLEEQGTEIYDSVFDTNVRALFLCLRHQLPAMLAQGRGSIVVNASVSGVR 156 Query: 444 S-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 + PG Y+ SKA+ TR A+E AP+G+R+N + PG ++T++ R G+ + A Sbjct: 157 NPNPGFSLYSASKAAAISLTRSAAMENAPRGIRINAIAPGRVVTDMMLRAGVGDVATVA- 215 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L R G P+EVA + +L+SD AS + G Sbjct: 216 -----AGLPLRRMGSPEEVAEAVVWLSSDAASYVVG 246 >UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; n=5; Proteobacteria|Rep: Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC - Comamonas testosteroni (Pseudomonas testosteroni) Length = 252 Score = 113 bits (271), Expect = 6e-24 Identities = 71/218 (32%), Positives = 113/218 (51%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 LS+ GA + + N E Q+++ + + L + D++KE+D ++ I G L Sbjct: 25 LSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSKEADYRAVVDAAIAQLGGLH 84 Query: 261 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 434 ++VNNAG + ++DR+ N++S+Y+ A+PH + G Sbjct: 85 IVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCALPHFAQQGHGVMVNVASTT 144 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G+R PG+ Y+ SKA++ T+ +ALE A GVR+N VNP + T + + E Sbjct: 145 GVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRINAVNPMIGETPMM-ADFMGMEDTP 203 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A ER LGR +PD+VA+ +AFLASD AS +TG Sbjct: 204 ANRERFLSRIPLGRFTRPDDVASAVAFLASDDASFLTG 241 >UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=1; Pseudoalteromonas haloplanktis TAC125|Rep: 7-alpha-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 264 Score = 112 bits (270), Expect = 7e-24 Identities = 71/221 (32%), Positives = 124/221 (56%), Gaps = 6/221 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 L+ GA + +T R +E++++ + + S L + D+ E + ++ KTI+H+G+LD Sbjct: 31 LADAGADIVVTARTIEDIEQTAAQIRQRGSRALVVACDVLDEQQRQSLVDKTIEHFGRLD 90 Query: 261 VLVNNAGIIETGTIENT---SLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXX 425 +LVNN G +G I+ T S A+ + N + + L+ ++ PH++ + +G Sbjct: 91 ILVNNVG--GSGAIKPTLSSSAAELENCFKLNTATAFDLSRISAPHMVNTSGQGSIINIS 148 Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 605 G + PG ++Y I+KA+++ T +A + APK VRVN ++ G LTE +G +++E Sbjct: 149 SVAGQLAQPGFISYGIAKAALNFMTLNLAQDFAPK-VRVNAISVGSTLTE-ALKGVMNDE 206 Query: 606 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A ++RT + R G+P++VAA FLAS A ITG Sbjct: 207 MEQAIVKRT----PMNRLGQPEDVAACALFLASPAAGYITG 243 >UniRef50_A1ZKI7 Cluster: 3-oxoacyl-acyl-carrier-protein reductase; n=1; Microscilla marina ATCC 23134|Rep: 3-oxoacyl-acyl-carrier-protein reductase - Microscilla marina ATCC 23134 Length = 253 Score = 112 bits (270), Expect = 7e-24 Identities = 70/218 (32%), Positives = 113/218 (51%), Gaps = 2/218 (0%) Frame = +3 Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGK 254 FL++ GA++ +TGR+ E L+ +++ K + L+I AD + +K+ + D +GK Sbjct: 26 FLAE-GAKVVVTGRSDEKLKATNEELAKIHANHFLTIKADAADVTSNKKVFEAAQDKFGK 84 Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX 434 +D+L NAG+ + + + A YD +MNTN++ ++L +P+ E Sbjct: 85 VDILFANAGVGRFMPLSDVTEAMYDEVMNTNLKGPFFLVQAGLPYFNEGASIILNTSVSN 144 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 + PG AY SKA + R A EL+ +RVN ++PG I T + + GL EE Sbjct: 145 QM-GMPGASAYAASKAGLRLLARVFAAELSAHKIRVNAISPGPIDTPIWGKTGLPEEAVQ 203 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ALGR G +E+A ++ FLAS AS +TG Sbjct: 204 EMGAGIASQVALGRFGTSEEIAKSVLFLASQDASFVTG 241 >UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Geobacillus kaustophilus Length = 256 Score = 112 bits (269), Expect = 1e-23 Identities = 77/225 (34%), Positives = 114/225 (50%), Gaps = 10/225 (4%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS---TLSITADLTKESDIEKIIKKTIDHYGK 254 L++ GA + L GR L++ +D + AD+T + + + YG Sbjct: 25 LAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADRFAADVTDHEQVRALAAYVQNRYGD 84 Query: 255 LDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 431 L VLVNNAGI T +E T ++D + N++S++ ++ P ++E Sbjct: 85 LHVLVNNAGISTHTKWLELTE-QEWDDVQRVNMKSVFLVSQTLAPLMIEGAKRERANRAI 143 Query: 432 XGIRSFPGVLA------YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGG 593 + S G A Y+ +KA V T+ +ALELAP G+RVN V+PG + T L R G Sbjct: 144 VNVASLSGHQAGAEIPHYSAAKAGVINLTKSLALELAPYGIRVNSVSPGFVETPLTER-G 202 Query: 594 LSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L E++ +ER ALGR G P+E+A IAFLAS AS +TG Sbjct: 203 LQNERFVKAIERNT---ALGRVGAPEEIANVIAFLASSEASYMTG 244 >UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 112 bits (269), Expect = 1e-23 Identities = 74/243 (30%), Positives = 121/243 (49%), Gaps = 4/243 (1%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSIT 188 M GKV L++ GA++ + NVE +K +D K L + Sbjct: 1 MRLEGKVCVVTGGATGIGEASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVE 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYY 365 D+++E +++++T+ +G++DVL NNAGI I G++ + + R NV I++ Sbjct: 61 CDVSREEGARRLVEETVGAFGRIDVLFNNAGINITEGSVPEMKVEDWRRTFAVNVDGIFW 120 Query: 366 LTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542 + A+P + ++ G + G AY SK +V TR +A++ A + +RV Sbjct: 121 CSRYAIPEMRKNGGGRIINTASPSSFVGWAGNAAYIASKGAVMSLTRAMAMDHAKENIRV 180 Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKET-HALGRPGKPDEVAATIAFLASDLASN 719 N + PG+IL+ L GL+ Q E KE+ H +GRPG P++VA + FLA D A Sbjct: 181 NAIVPGLILSPL----GLNWVQQQEDPEAVKESIHPIGRPGYPEDVAPVVVFLAQDDAEF 236 Query: 720 ITG 728 TG Sbjct: 237 ATG 239 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 112 bits (269), Expect = 1e-23 Identities = 76/249 (30%), Positives = 124/249 (49%), Gaps = 9/249 (3%) Frame = +3 Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSI 185 T +F GKV L+ GA + + + E + K + + + Sbjct: 3 TFDFTGKVAIVTGGGGGIGREACLKLAAGGANVVVADLSDELGEETAGKIRENGGEAIFV 62 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIY 362 D++K D++ ++ +D YGK+D+L+NNAG + + + +D+LM NVR ++ Sbjct: 63 RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122 Query: 363 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 +PH++ K G G+ P ++AY SK +V T+ +E AP GVR Sbjct: 123 LGMKYVLPHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAGIEAAPSGVR 182 Query: 540 VNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHA----LGRPGKPDEVAATIAFLA 701 VN V PGV+ TE+ R+ G + AA E+T++ A GR +P+EVA + +LA Sbjct: 183 VNAVCPGVVDTEMMRKIENGFAGGDSAA-AEQTRQQMAASAPTGRYTQPEEVANVLLYLA 241 Query: 702 SDLASNITG 728 SDL+S+I G Sbjct: 242 SDLSSHIIG 250 >UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=4; Bacteria|Rep: Predicted short chain dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 250 Score = 111 bits (268), Expect = 1e-23 Identities = 63/211 (29%), Positives = 108/211 (51%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA+++ GRN E L ++ +++ D T D+++++ +T+ +G +D++V N Sbjct: 31 GAKVAAFGRNTEALDALA--AAHAGKVVTVKGDATCAEDLQRLVDETLKAFGGVDIVVPN 88 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AGI + E+++ ++ + N+ + L +PH+ + FPG Sbjct: 89 AGIARVVSFEDSTREAFETQFSVNLFAAAETVRLFLPHIRRGGSVQFITTFLTQV-GFPG 147 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 + Y+ SKA++ F + +A ELAP+G+RVN + PG I T L GL + A + Sbjct: 148 LAIYSASKAALKSFAQTLAAELAPRGIRVNSIAPGPIATPLWGTVGLPPDVLGAVAGQIN 207 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 G GKP+++A T FLASD A NI G Sbjct: 208 SRLMTGEFGKPEDIAETSVFLASDGAKNIYG 238 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 111 bits (268), Expect = 1e-23 Identities = 67/170 (39%), Positives = 95/170 (55%), Gaps = 1/170 (0%) Frame = +3 Query: 222 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LE 398 +I T+ +G+LD+LVNNAGI G + SL +D L+ NV S++Y A+PH+ + Sbjct: 72 LIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRAAIPHMRRQ 131 Query: 399 SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578 G G+R AY+ SKA+V FTR +AL+ A + +RVN + PG + TE+ Sbjct: 132 GGGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALDHADENIRVNAICPGSVETEM 191 Query: 579 QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +S Y A + +T R G+PD+VAA AFLASD AS I G Sbjct: 192 NNL-MMSRPDYIA---QWIKTIPANRFGRPDDVAALAAFLASDDASFIVG 237 >UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=1; Neosartorya fischeri NRRL 181|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 255 Score = 111 bits (268), Expect = 1e-23 Identities = 75/223 (33%), Positives = 113/223 (50%), Gaps = 8/223 (3%) Frame = +3 Query: 84 LSKLGAQ-LSLTGRNVENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKL 257 L+KLGA L+L+ NVE LQK +C ++ S +++T D+++ + + +T+ +G+L Sbjct: 27 LAKLGAAGLALSDVNVEGLQKTKDECSRYESNVTVTRVDVSRNDQVTRWASETVQQFGRL 86 Query: 258 DVLVNNAGIIE---TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXX 428 D N AGI T E S +DRLM+ N++ + +PHL G Sbjct: 87 DGAANIAGIAMGDGTTNCETISPESWDRLMDVNLKGVMLCMRAQLPHLPRPGGVIVNVSS 146 Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG---GLS 599 G+R P AY+ SK V + A E P G+R+N + PG + T + R G GL Sbjct: 147 TSGLRGLPHNAAYSSSKFGVIGLSASAAGEFGPLGIRINSLLPGPVDTAIFRDGEARGLF 206 Query: 600 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + Q +K T LGR G+ E+A + FL SD AS +TG Sbjct: 207 DSQIL-----SKAT-CLGRMGQAHEIANVLCFLLSDDASYVTG 243 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 111 bits (268), Expect = 1e-23 Identities = 70/214 (32%), Positives = 112/214 (52%), Gaps = 3/214 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQK--VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 GA++ +T + E K V++ K S ++I AD+ E D++K+I K YG+LD+LV Sbjct: 31 GAKVVITWESHEESAKNVVNEIHHKNGSAMAIQADVRNEDDVKKVINKIKGEYGRLDILV 90 Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRS 446 NNAGI++ + T ++D L+ TN + + + A +L+ K G G+ Sbjct: 91 NNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYSRAAAKLMLKHKSGRIINISSVVGVYG 150 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626 G Y+ +K+ + FT+ +A EL P G+ VN + PG I T+L + +E L Sbjct: 151 SKGQSVYSATKSFLIAFTKSLAKELGPFGITVNAIAPGFIDTDLTH--DVKDETRQDLLS 208 Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 LGR G+ D++A + FLASDL S + G Sbjct: 209 HI----PLGRIGQADDIAKAVVFLASDLGSYVNG 238 >UniRef50_Q126U8 Cluster: Short-chain dehydrogenase/reductase SDR; n=14; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 274 Score = 111 bits (267), Expect = 2e-23 Identities = 65/196 (33%), Positives = 104/196 (53%), Gaps = 12/196 (6%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 L + D+ ++ ++ ++ +TI +G++DVLVNNAGI + A +D ++ N++ Sbjct: 65 LYVHCDVGDKAQVDALVAQTIAAHGRIDVLVNNAGIFRAADFLEITEADFDAVLRINLKG 124 Query: 357 IYYLTMLAVPHLLE-----------SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTR 503 + + + S+G + + P + +YN+SK ++Q TR Sbjct: 125 SFLVGQAVAREMARAEARPGIGGSASRGSIVNMSSVNSVLTIPTIASYNVSKGGINQLTR 184 Query: 504 CVALELAPKGVRVNCVNPGVILTELQRRGGL-SEEQYAAFLERTKETHALGRPGKPDEVA 680 +AL LA KG+RVN V PG I T+L + L SEE A + RT + R G+P E+A Sbjct: 185 VMALALADKGIRVNAVAPGTIATDLAAKAVLTSEEAKARIMSRT----PMKRLGEPSEIA 240 Query: 681 ATIAFLASDLASNITG 728 T+A+LASD AS ITG Sbjct: 241 DTVAYLASDAASYITG 256 >UniRef50_Q0RF25 Cluster: Putative oxidoreductase; short-chain dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep: Putative oxidoreductase; short-chain dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 297 Score = 111 bits (267), Expect = 2e-23 Identities = 78/241 (32%), Positives = 119/241 (49%), Gaps = 4/241 (1%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITAD 194 FAG VV + GA + + R ++ ++ ++ S + D Sbjct: 36 FAGTVVLVTGAGRGLGRTIAEAFAVEGATVVVAARTARYGERTVREFRERGLSASLVIGD 95 Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM 374 L + +D+ + + + +G LDV+V++A G + D L+ +NV +++++T Sbjct: 96 LAERADVATMFDEAVARHGALDVVVHSAADNAQGLLAEIDDDTLDYLLRSNVHALHWITR 155 Query: 375 LAVPHLLESK--GXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 AVPHL SK G R F PG+ AY +KA ++ F R +A EL P GVRVN Sbjct: 156 AAVPHLTRSKLPGRMIFISSGAANRVFSPGLNAYGSTKAYLESFARGLAGELGPLGVRVN 215 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 V PG+ +TE + G L+ Q A T+ LGR G P+E+AA + FLAS AS IT Sbjct: 216 VVGPGLTVTE-RMLGHLTHAQADAL----ASTYPLGRAGLPEEIAAAVLFLASREASYIT 270 Query: 726 G 728 G Sbjct: 271 G 271 >UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Pedobacter sp. BAL39|Rep: Short-chain dehydrogenase/reductase SDR - Pedobacter sp. BAL39 Length = 250 Score = 111 bits (267), Expect = 2e-23 Identities = 64/212 (30%), Positives = 112/212 (52%), Gaps = 1/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA ++ GRN E L++ + D F ++I D+T D+E++++ T + +GK+D+LV Sbjct: 30 GASGAIVGRNQETLKRAASQLGDGF---IAINGDVTNPGDLERMMRNTSEQFGKIDILVA 86 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452 NAG TGT+ + S + YD+ M+ N++S+Y+ A+P++ + R++P Sbjct: 87 NAGAGTTGTVADISESDYDKTMDLNLKSVYFTVQKALPYMADGSS-IILIGSNAAHRAYP 145 Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632 Y +KA+V + + +L + +RVN + PG T + + EQ A Sbjct: 146 SFGLYGAAKAAVIFLAKSFSNDLLDRKIRVNVITPGTTDTPAFDK-FVPAEQIEALKTHF 204 Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728 T +GR G+P ++ T FLASD +S + G Sbjct: 205 AGTMPIGRIGQPSDIGKTAVFLASDDSSFLLG 236 >UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 253 Score = 111 bits (266), Expect = 2e-23 Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 1/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ + N+E +KV+++ + ++T E+ + ++ T+ +G+LD+ VNN Sbjct: 31 GARVMIGDINLEQGRKVAEELSSLGDIAFVENNVTAEASCQNAVEHTVKRFGRLDIAVNN 90 Query: 276 AGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452 AG+I ET + S + R MN N+ +++ V +L + G + P Sbjct: 91 AGVIGETKPLLELSAEGWQRTMNININGVFFGLKAQVNQMLATGGSIINLASIASKIATP 150 Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632 Y SK +VD T+ AL+ A G+R+N V PGVI T L G +++ + ++ Sbjct: 151 SCADYITSKHAVDGLTKAAALDYATMGIRINSVGPGVIETPLLGTIGQTKDAQGS-IKHA 209 Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728 H +GR GK EVA I +LASD AS TG Sbjct: 210 IGMHPMGRVGKVGEVANLITWLASDQASFCTG 241 >UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 239 Score = 110 bits (265), Expect = 3e-23 Identities = 68/203 (33%), Positives = 112/203 (55%), Gaps = 2/203 (0%) Frame = +3 Query: 126 VENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI 302 +++++K+ ++ + SI AD+T + I++++ + +GK+DVL+NNAGII+ G I Sbjct: 33 IDDIEKLREEFSSPQGSFSIEKADVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYI 92 Query: 303 ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISK 479 S ++ ++N N+ ++ T H++ + G GI PG Y+ +K Sbjct: 93 MLMSAKDWNDVINVNLTGVFNCTKAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAK 152 Query: 480 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRP 659 V FT ++ ELAP +RVN V PGVI T++ L + + ++ KE L R Sbjct: 153 GGVIAFTMALSKELAPFCIRVNTVAPGVIETDI--IDSLDKNKRNSY----KEHIPLKRF 206 Query: 660 GKPDEVAATIAFLASDLASNITG 728 GKP+EVA+ + FLAS AS ITG Sbjct: 207 GKPEEVASVVRFLASSEASYITG 229 >UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 259 Score = 110 bits (265), Expect = 3e-23 Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 1/183 (0%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + DL++ + E+++++ + G LDVLVNNAGI +T YD + + N++ + Sbjct: 59 VRGDLSRVPECERVVEEAAEALGGLDVLVNNAGITRALDFLDTDEETYDAIFDLNMKGYF 118 Query: 363 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 + AVPH+LE+ G G FP AY +K ++ FTR +A+ELA +G+R Sbjct: 119 FCARSAVPHMLEAGGGSIVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIR 178 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN + PG+I E+ R + Y+ E+ +E GR GKP +V AFLASD A Sbjct: 179 VNAIGPGLI--EVPRYYDI--PGYSP--EQGRELVPWGRVGKPKDVGPAAAFLASDAADF 232 Query: 720 ITG 728 ITG Sbjct: 233 ITG 235 >UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: Oxidoreductase - gamma proteobacterium HTCC2207 Length = 253 Score = 110 bits (264), Expect = 4e-23 Identities = 67/220 (30%), Positives = 111/220 (50%), Gaps = 4/220 (1%) Frame = +3 Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 F+S+ GA++ L N + Q + + + + D+ + +E +++ T+D +G +D Sbjct: 25 FVSE-GAKVMLADINTDITQPLVNELGAYRCAC-VAVDVAEADQVENMVRTTVDTFGSID 82 Query: 261 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX- 434 V V NAG + G+I +T ++ D+++ NVR ++ +P + + G Sbjct: 83 VFVANAGTEGKIGSIMDTDVSNLDKVLAVNVRGVWLGLHYVMPVMRDGGGGSIIITSSGA 142 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQ 608 G++ P AYN SK +V RC ALE A G+RVN VNPG + T + G +E Sbjct: 143 GVQGSPNTAAYNTSKHAVIGLMRCAALESAQFGIRVNTVNPGAVETRMMESIEDGFAEAG 202 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F + LGR G+P+E+A + FL SD +S TG Sbjct: 203 AGDFRAMVEAVTPLGRYGQPEEIANMMVFLGSDDSSYCTG 242 >UniRef50_Q5V6V0 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=4; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 268 Score = 110 bits (264), Expect = 4e-23 Identities = 66/218 (30%), Positives = 111/218 (50%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L+ +GA +++ NVE ++ + + D ++ D+T E +E +++ D G +DV Sbjct: 42 LTDMGADVAIADVNVEKAERTASELDGETDVIATEVDVTDEGSVEAMVEDVTDRLGPIDV 101 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGI 440 LVNNAGI+E E TS+ + R+++ N+ ++ +L +G G Sbjct: 102 LVNNAGIVENSPAEETSVESWRRVVSVNLDGVFLCAKHVGQQMLNRGEGRIVNISSMSGF 161 Query: 441 R-SFPGVLA-YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 + P A YN +KA V T+ +A+E +GVRVN + PG + TEL E+ Sbjct: 162 DVNVPQKQASYNTTKAGVRMLTQSLAVEWGDQGVRVNAIAPGYMRTELVDE---VLEENP 218 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E E +GR G+P+E+ + +LASD +S +TG Sbjct: 219 EMEETWLENTPMGRLGRPEELKELVVYLASDASSYMTG 256 >UniRef50_A4XED1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 269 Score = 109 bits (263), Expect = 5e-23 Identities = 67/194 (34%), Positives = 98/194 (50%), Gaps = 7/194 (3%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII------ETGTIENTSLAQYD 329 A +++ DL +E +E ++++T+ H+G+LDVL NNA ++ G +E A +D Sbjct: 55 AGAIALPLDLEQEQSVETLVERTVAHFGRLDVLHNNAALLGPEIAQADGDVERMGTALWD 114 Query: 330 RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCV 509 R NVR A+PHL E++G ++ AY+ SKA+V Q TR + Sbjct: 115 RTFAVNVRGTMIACRAALPHLRETRGCIVNTVSNLALQGHLIQAAYSSSKAAVIQMTRAI 174 Query: 510 ALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHAL-GRPGKPDEVAAT 686 A GVR N V PG+ +T R E + L + E L R G P ++A Sbjct: 175 AASHGKAGVRCNAVAPGMTMTPALR------EAFPPALRQVVEDETLRDRLGDPRDIAEA 228 Query: 687 IAFLASDLASNITG 728 IAFLASD A N+TG Sbjct: 229 IAFLASDAARNVTG 242 >UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplantae|Rep: Tropinone reductase 1 - Datura stramonium (Jimsonweed) (Common thornapple) Length = 273 Score = 109 bits (263), Expect = 5e-23 Identities = 75/223 (33%), Positives = 120/223 (53%), Gaps = 8/223 (3%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHY--GK 254 L+ LGA++ RN + L + + +K + DL ++ +K+++ T+ H GK Sbjct: 41 LAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSRTERDKLMQ-TVAHVFDGK 99 Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431 L++LVNNAG++ ++ + Y+ +M TN + Y+L+ +A P L S+ G Sbjct: 100 LNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSI 159 Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ----RRGGLS 599 G + P V Y+ SK +++Q T+ +A E A +RVN V PGVILT L ++ Sbjct: 160 AGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQ 219 Query: 600 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +E+ F+ +T +GR GKP EV+A IAFL AS ITG Sbjct: 220 KEEIDNFIVKT----PMGRAGKPQEVSALIAFLCFPAASYITG 258 >UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces coelicolor Length = 255 Score = 109 bits (262), Expect = 7e-23 Identities = 71/245 (28%), Positives = 113/245 (46%), Gaps = 5/245 (2%) Frame = +3 Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSI 185 T F GK L+ GA + + GR L + + ++ L++ Sbjct: 3 TQRFTGKTALVTGAGSGIGRAVALALAAEGAHVVVAGRARGPLDETAALVEQAGGKALAV 62 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIY 362 TAD+T+ D++ ++ ++H+G LDV VNNAG+ G + + S + ++ NV ++ Sbjct: 63 TADVTRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVF 122 Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGI---RSFPGVLAYNISKASVDQFTRCVALELAPKG 533 V H+ G + PG AY +KA+V TR AL+ G Sbjct: 123 LALRAEVRHMRAQPGGGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAALDHIGDG 182 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 VR+N V+PG T + R G +E A ER ++ LGR EVAA + +LASD A Sbjct: 183 VRINAVSPGATATSMSLRPGETE---AGRAERMRQETPLGRVSAVAEVAAAVLYLASDDA 239 Query: 714 SNITG 728 +++ G Sbjct: 240 ASVVG 244 >UniRef50_A0FWP6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia phymatum STM815 Length = 257 Score = 109 bits (262), Expect = 7e-23 Identities = 72/238 (30%), Positives = 109/238 (45%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 M+FA K L GA++++TGR+ + L + + + S L I A Sbjct: 1 MSFANKTALITGGNGGIGFAAARLLIAQGARVAITGRDQKKLDEAAAELGP--SALPIRA 58 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D+ + I+ ++K D +GKLD++ NAG+ + T+ +++ +M TNV S++ Sbjct: 59 DINDPAAIDAVMKTIADTFGKLDIVFANAGVSGATPVGETTAEKFEAIMRTNVTSVFLTV 118 Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551 AVP L+ G PG AY+ SKA++ R +A EL +G+RVN V Sbjct: 119 QAAVP-LMGEGGAIVLNGSVMRQLGAPGSSAYSASKAAISGMARVLASELVTRGIRVNTV 177 Query: 552 NPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 PG T + RG A + R DEVA FLASD AS +T Sbjct: 178 IPGGTRTSIWTRGDREGATLDATEAALSPMIPMNRFALADEVAQAAVFLASDAASGMT 235 >UniRef50_Q930L7 Cluster: Putative; n=1; Sinorhizobium meliloti|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 253 Score = 109 bits (261), Expect = 9e-23 Identities = 71/241 (29%), Positives = 120/241 (49%) Frame = +3 Query: 6 VTMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI 185 ++ F GKV L + GA + ++GR + L V+ S + + Sbjct: 1 MSKRFDGKVAIVTGGGSGIGAAIANRLLEEGASVMMSGRTEKRLSDVASKMPADRSGIFV 60 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365 A+++ D + ++ T++ +G++D +VN AG+ GTI+ TS +D + +++ ++Y Sbjct: 61 -ANVSSRPDCDALVAATVERFGRIDTVVNAAGMNFVGTIQETSDQDWDECIASDLSGVFY 119 Query: 366 LTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 ++ AVPHL E+KG + AYN +K V TR A +L GVR N Sbjct: 120 MSRAAVPHLKETKGSIVNIGSVSSLGGGWSHAAYNAAKGGVANLTRSAACDLGKFGVRAN 179 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 V PG+ +T + + ++ A LE+ + L R G+P A+ +AFLASD A+ IT Sbjct: 180 TVAPGLTVTGMVE--AIMDDD--ALLEKAWDRIPLRRAGQP---ASAVAFLASDEAAWIT 232 Query: 726 G 728 G Sbjct: 233 G 233 >UniRef50_A3IE79 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reductase; n=2; Bacillaceae|Rep: 3-ketoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. B14905 Length = 248 Score = 109 bits (261), Expect = 9e-23 Identities = 63/186 (33%), Positives = 106/186 (56%), Gaps = 7/186 (3%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYL 368 ++ +E + I ++ +D YG++D LVN GI + T IE ++ +++RLM+ NV+S++ Sbjct: 56 NVLQEERVNDIFQQIVDKYGRIDGLVNALGIAQAATPIEQVTMDEWNRLMDVNVKSLFIT 115 Query: 369 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 VP + + KG +R PG+ AY SK + + FTR +A+ELAP +RVN Sbjct: 116 AKAVVPFMKKQQKGSIVTIASISAVRPRPGLQAYIASKGAAESFTRGLAIELAPNQIRVN 175 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTK-----ETHALGRPGKPDEVAATIAFLASDL 710 ++PG + Q G + + A +E+TK ++ LGR KP ++A +++L SD Sbjct: 176 TIHPGP--ADTQMLGQFAAQ--GADVEQTKQSVFVQSVPLGRLVKPSDIAGAVSYLLSDA 231 Query: 711 ASNITG 728 AS +TG Sbjct: 232 ASMVTG 237 >UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR precursor - Nocardioides sp. (strain BAA-499 / JS614) Length = 258 Score = 109 bits (261), Expect = 9e-23 Identities = 65/219 (29%), Positives = 110/219 (50%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L+ GA + + E+ ++ V+ D +++ A++ +++E I K + YG L+ Sbjct: 28 LASEGAAVGVLDLRAESAEETVAAIVDSGGRAIALAANVADSAEVEAAIAKVVAEYGGLN 87 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXG 437 VL NNAG G++ + + ++R + N + + + AVPHL S G Sbjct: 88 VLYNNAGCDSRGSVADATDEDWERAFSVNAKGTFVCSRAAVPHLTASGGGAIVNQGSVAA 147 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQY 611 + P AY +K +V TR +A++LAP+ +RVN + PG + T L + Sbjct: 148 LVGVPNFAAYCAAKGAVVALTRSMAIDLAPRKIRVNVICPGTVFTPLMEPMLRARGDGDL 207 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A L +T + +GR G P+E+A AFLASD +S +TG Sbjct: 208 EAGLAKTLVKYPIGRLGTPEEIARVAAFLASDDSSFLTG 246 >UniRef50_Q23618 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 109 bits (261), Expect = 9e-23 Identities = 78/244 (31%), Positives = 125/244 (51%), Gaps = 16/244 (6%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST----LSI 185 F+GKVV + GA++ L GR+ ++++K K C + + L Sbjct: 6 FSGKVVLISGSSKGIGQATAVKFAAEGAKIVLNGRSADDVEKTRKLCMEVGAKPWDLLPT 65 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE---TGTIE-NTSLAQYDRLMNTNVR 353 D+T E ++ ++ I ++GKLD+L+NNAG +E TG + DR N+N + Sbjct: 66 VGDITNEDFVKMMVNTVIHNFGKLDILINNAGTLEVDMTGKEGWEMGVDVMDRSWNSNFK 125 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP-GVLA---YNISKASVDQFTRCVALEL 521 S+ LT A+PHL+++KG + S P GV++ Y + KA++DQ +R +A E Sbjct: 126 SVLMLTQAAMPHLIKTKGDIVNVSTF--LSSGPIGVMSMPYYAVPKAALDQMSRSMAHEY 183 Query: 522 APKGVRVNCVNPGVILTELQRR----GGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 689 KGVR+N VNPG++ T R G + + +++ E LGR + +VA TI Sbjct: 184 MLKGVRLNTVNPGLVSTSFFARLPGVGDDNARKMENYVQSKTEYIPLGRVCQASDVAETI 243 Query: 690 AFLA 701 FLA Sbjct: 244 LFLA 247 >UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=3; Pezizomycotina|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Aspergillus clavatus Length = 249 Score = 109 bits (261), Expect = 9e-23 Identities = 65/186 (34%), Positives = 98/186 (52%), Gaps = 2/186 (1%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVR 353 +++ AD++K DI +++K T+D +GK+DVLV NAG++ + G + + + +D L NVR Sbjct: 57 IAVQADVSKREDIARLVKTTVDRFGKIDVLVLNAGLLWQKGDLLSITEQDFDTLFAANVR 116 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF-PGVLAYNISKASVDQFTRCVALELAPK 530 S + A PHL E P L Y SK +V+Q TR +A +L + Sbjct: 117 SPLFTIQEAAPHLTEGGRVMLFSTSLAAFSGVTPNYLLYAASKGAVEQMTRVLAKDLGRR 176 Query: 531 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 710 G+ VN + PG I T+ G + EQ T GR GKP+EVAA + F+ASD Sbjct: 177 GITVNTIAPGPIGTDAYFVG--NNEQMVQLQSNLAPT---GRLGKPEEVAAVVNFIASDQ 231 Query: 711 ASNITG 728 + + G Sbjct: 232 SQWVNG 237 >UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Methanoregula boonei 6A8|Rep: Short-chain dehydrogenase/reductase SDR - Methanoregula boonei (strain 6A8) Length = 253 Score = 109 bits (261), Expect = 9e-23 Identities = 64/187 (34%), Positives = 100/187 (53%), Gaps = 1/187 (0%) Frame = +3 Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 350 S ++I AD+T E +++++ ++ + YG+LD+LVNNAGI++ + T + +Y +M+ N Sbjct: 62 SAMAIRADVTCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNC 121 Query: 351 RSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527 + + T A ++ K G G+ G AY SK+ V FT+C A EL Sbjct: 122 KGTFLCTQHAAKIMVRQKAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAKELGA 181 Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 + VN V PG I T+ L+ + + E + ALGR G PD+VA I FL SD Sbjct: 182 FNITVNAVAPGFIDTD------LTADTRSQVKEDILKNIALGRIGTPDDVAKVIVFLGSD 235 Query: 708 LASNITG 728 LA ++G Sbjct: 236 LAGYVSG 242 >UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1 Length = 263 Score = 108 bits (260), Expect = 1e-22 Identities = 67/185 (36%), Positives = 99/185 (53%), Gaps = 3/185 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSI 359 +TAD+ E D+E +++ + YG+LD NNAG + IE T+ +YD +M TNVRS Sbjct: 60 VTADVLSERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTN-DEYDTVMATNVRSA 118 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 ++ + +L G +R+ PG+ AY+ SKA + TR VA+E A K + Sbjct: 119 FWCMKYQLKAMLAGGGGAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNI 178 Query: 537 RVNCVNPGVILTELQRRG-GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 R N V+PG++ +E+ G L + AF + R G P EVA +AFL SD A Sbjct: 179 RANTVSPGIVESEMATAGWRLHDRMGRAF---ASSFQPMNRVGTPQEVAGLVAFLLSDKA 235 Query: 714 SNITG 728 S +TG Sbjct: 236 SFLTG 240 >UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=32; cellular organisms|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Methanosarcina acetivorans Length = 256 Score = 108 bits (260), Expect = 1e-22 Identities = 71/243 (29%), Positives = 116/243 (47%), Gaps = 3/243 (1%) Frame = +3 Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188 T F GKV ++ GA ++LT N Q V + + L+I Sbjct: 6 TKQFLGKVAFVTGGATGIGQATAVAFAREGANVALTYHNQGAEQTVRRIEELGGQALAIK 65 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 365 D+ +E D++ I+K I +G+LD NNAGI +T + +++R++ TN+ ++ Sbjct: 66 CDVIREEDVKNAIEKIIQTFGQLDYAFNNAGIEGKTVITAEYPVEEWNRVIATNLTGVFL 125 Query: 366 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542 +P +L + G G+ FP + Y SK V T+ AL+ A +R+ Sbjct: 126 CMKYEIPQMLKQGAGAIVNCSSGAGLTGFPDISPYVASKHGVVGLTKTAALDYAKSNIRI 185 Query: 543 NCVNPGVILTE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 N V PG+ T ++R G + E Y E+ E +GR G+P+E+A + +L SD AS Sbjct: 186 NAVCPGMTDTPMMERYSGGTPEGY----EKIIEQEPIGRMGRPEEIAIAVLWLCSDAASF 241 Query: 720 ITG 728 +TG Sbjct: 242 VTG 244 >UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 248 Score = 108 bits (260), Expect = 1e-22 Identities = 68/208 (32%), Positives = 109/208 (52%), Gaps = 2/208 (0%) Frame = +3 Query: 111 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 290 +TG+ E ++V K +++ D+T E++ + D YG +D+LVNNAGI Sbjct: 38 ITGKENEVAEEVRK---LGGQGMALRLDVTDGKMAEEVARTVFDKYGHIDILVNNAGIYP 94 Query: 291 TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG-IRSFPGVLA 464 + + R++N N+ ++ +T VP++++ K G G + F G+ Sbjct: 95 FKPFMEMTFNDWYRVINVNLNGVFNVTRAVVPYMVKQKNGRIINIASIAGAVMGFMGLTH 154 Query: 465 YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETH 644 Y+ SKA + FTR +ALELA G+ VN + PG I T G SEEQ + Sbjct: 155 YSASKAGIVGFTRALALELARYGITVNAIAPGAINTPGAATG--SEEQVRMMINAI---- 208 Query: 645 ALGRPGKPDEVAATIAFLASDLASNITG 728 +G+ G P+++A+ +A+LASD AS ITG Sbjct: 209 PMGKLGTPEDIASAVAYLASDEASYITG 236 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 108 bits (260), Expect = 1e-22 Identities = 72/241 (29%), Positives = 116/241 (48%), Gaps = 2/241 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-IT 188 MNF GKVV ++ GA++++ + E ++ + + I Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 D+ K D E+I+KKT++ +G+LD+LVNNAGI+ G IE TS +D+ M NV+ + L Sbjct: 61 GDVAK--DAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118 Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + AV + + G G+ P Y++SKA++ TR +A++ G+RVN Sbjct: 119 SKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVN 178 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 V PG +E + L++ + R GK +E+A I F A D A +T Sbjct: 179 AVCPGTTQSEGLMARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEAGFMT 238 Query: 726 G 728 G Sbjct: 239 G 239 >UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 247 Score = 108 bits (259), Expect = 2e-22 Identities = 69/218 (31%), Positives = 120/218 (55%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTG-RNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 257 L+K G +++T ++ ++ ++V ++ K L+I D++K ++EK ++K I+ +G + Sbjct: 25 LAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVSKYHEVEKAVEKVIEEFGSI 84 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 434 DV+VNNAGI + I ++D++++ N++ + + A ++++ KG Sbjct: 85 DVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIKFASKYMIKKRKGKIINISSVV 144 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G+ G Y SKA + T+ VA ELA +G+ VN V PG I T++ L E+ Sbjct: 145 GLMGNVGQANYAASKAGIIGLTKSVAKELASRGITVNAVAPGFIETDM--TNVLKEDIKE 202 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A L ++ L R GKP+EVA +AFLAS + ITG Sbjct: 203 AML----KSIPLKRAGKPEEVAEVVAFLASSASDYITG 236 >UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 260 Score = 108 bits (259), Expect = 2e-22 Identities = 71/218 (32%), Positives = 113/218 (51%), Gaps = 7/218 (3%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 GA + + RN +N+ + + T I + D +K++ T+ +GK+++LV Sbjct: 34 GASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILV 93 Query: 270 NNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIR 443 NN GI G I S +D+L NV++ + +T L PH+ E G + Sbjct: 94 NNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYK 153 Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR---RGGLSEEQYA 614 S PG+ AY ++K ++ TR +A+ LA +RVN + PGVI T++ + GG E+ Sbjct: 154 SPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKEL 213 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ ALGR G PD+ A T+A+LASD +S ITG Sbjct: 214 TDIQEI----ALGRLGVPDDCAGTVAYLASDDSSYITG 247 >UniRef50_Q6MLN8 Cluster: Oxidoreductase; n=1; Bdellovibrio bacteriovorus|Rep: Oxidoreductase - Bdellovibrio bacteriovorus Length = 321 Score = 107 bits (258), Expect = 2e-22 Identities = 72/216 (33%), Positives = 110/216 (50%), Gaps = 2/216 (0%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTID-HYGKLDV 263 SK G + L GRN E LQ V+ C AS +S DL+ E+ + K + + + +++ Sbjct: 96 SKNGYFVYLMGRNKERLQDVALKCRSGASIVS--CDLSDEAALNKRLGEVMGAKIHRVEC 153 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX-GI 440 +VNNAGI E+ T E+ S + R N+ + P+ E G G+ Sbjct: 154 VVNNAGIYESNTTESGSDELWSRQFEVNMLGPLRIVRAFFPYFKEQGGGSIVNISSTLGL 213 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 R AY+ KA++ +T +ALE P +R NCV PG++ T + + L E+Q A Sbjct: 214 RPQGPTSAYSAVKAALVNWTESLALEGGPLNIRANCVCPGLVDTPIHQFHALPEDQKKAT 273 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L++ LGR GKP+++A + FL SDL+S TG Sbjct: 274 LDKMGGLQPLGRIGKPEDIARAVYFLGSDLSSWTTG 309 >UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 272 Score = 107 bits (258), Expect = 2e-22 Identities = 68/219 (31%), Positives = 118/219 (53%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA++++ NV+ +V+ D ++I AD++K++D E + ++T++ +G +D Sbjct: 27 LAREGARIAVVDLNVDAATRVASSIDPDGKRAIAIRADISKKADTEAMARQTLEAFGTID 86 Query: 261 VLVNNAGIIETGTIE-NTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 434 +LVNNAG+ + + + +DR+M N + I + +P + + KG Sbjct: 87 ILVNNAGVGGASALACDVTEENWDRVMGVNAKGILFCCQAVIPAMKAQGKGKIVNIDSIA 146 Query: 435 GIR-SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 GIR ++ + Y SK +V T+ +A ELA + + VN V PG ILT +E++ Sbjct: 147 GIRMAYFSSVDYTASKHAVTGLTQHLAWELADQRINVNAVCPGGILTPAIEAYASAEKRE 206 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A + T LGR KP+E+ ++FLASD A ITG Sbjct: 207 ALI----RRTVPLGRFCKPEEIGEAVSFLASDRADMITG 241 >UniRef50_Q2G4A5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 246 Score = 107 bits (258), Expect = 2e-22 Identities = 67/211 (31%), Positives = 110/211 (52%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA+L++TGRN E L+ V+++ D L I +D+ +D E+ +++ D G +DVL N Sbjct: 29 GAKLAITGRNAETLRAVAEELD----ALCIRSDMGDLNDTERALEEIEDALGGIDVLFVN 84 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG+ + + + +D++ + N+R ++ A+P L+ G + + PG Sbjct: 85 AGVGGFAMVPDVTPEFWDQIHSVNLRGAFFAIQRALP-LMRDGGSIVITGSIGSMAAVPG 143 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 +AY +KA + R V EL P+ +RVN V+PG TE+ +R S E+ + Sbjct: 144 NVAYAAAKAGLRAMARIVGKELLPRRIRVNMVSPGPTDTEIFKRDA-SAEEIQGMKDMLS 202 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 +GR G +EVA + FLAS AS I G Sbjct: 203 SVVPIGRMGTSEEVARAVLFLASAEASFING 233 >UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR precursor - Clostridium phytofermentans ISDg Length = 258 Score = 107 bits (258), Expect = 2e-22 Identities = 63/220 (28%), Positives = 113/220 (51%), Gaps = 6/220 (2%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLDV 263 +K GA ++L R +E L +V + +K +++ D+T E ++ ++ ID +G +D+ Sbjct: 30 AKAGADVALLARRIEKLNEVKAEIEKIGRKVVAVGCDVTNEESVKTAMQTVIDTFGHIDI 89 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGI 440 L+NNAGI G +++ S+ +D+ +TNV+ I+ + VP + E G + Sbjct: 90 LLNNAGIAVRGGVDSMSVEDWDKSYDTNVKGIFLASKYVVPQMKERGYGKIINIASVNAV 149 Query: 441 --RSFPGVL--AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 F + +YN SKA+V TR +A A G+ VN + P + +E+ E+ Sbjct: 150 VADKFDAFIRHSYNSSKAAVVGLTRGMAASYARYGITVNAIGPALFESEMTSDTLFKSEE 209 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 FL + + GRPG+ E+ T+ +L+SD +S + G Sbjct: 210 ---FLNKYNTMNPAGRPGRKGELNGTVLYLSSDSSSYVQG 246 >UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacillus|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 260 Score = 107 bits (258), Expect = 2e-22 Identities = 65/190 (34%), Positives = 107/190 (56%), Gaps = 6/190 (3%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVR 353 +++ D+T ++ + KT+ + +LD++ +NAGI T IE+ + +++ ++TN++ Sbjct: 57 MALEVDVTDPEQVKTAVDKTVREWDRLDIVFSNAGINGTVAPIEDLTPDDWEKTLSTNLK 116 Query: 354 SIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP--GVLAYNISKASVDQFTRCVALELAP 527 + LT A+PH+ G G R F G+ AY+ SKA F + ALELA Sbjct: 117 GTFLLTKYAIPHMKNRGGSIIITSSINGNRIFSNIGMSAYSSSKAGQVAFMKMAALELAR 176 Query: 528 KGVRVNCVNPGVILTELQRRGGLSE--EQYAAFLERTKETHAL-GRPGKPDEVAATIAFL 698 +RVN V PG I T++++ +E E+ +E + L GRPGKP+EVA + FL Sbjct: 177 YKIRVNAVCPGAIETKIEQNTNRTEELEKVQIPIEFPEGDQPLSGRPGKPEEVADLVLFL 236 Query: 699 ASDLASNITG 728 ASD +S+I+G Sbjct: 237 ASDDSSHISG 246 >UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 249 Score = 107 bits (257), Expect = 3e-22 Identities = 69/212 (32%), Positives = 109/212 (51%), Gaps = 3/212 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA L L R+ E L VS+ + A + + D+T + ++ + + +G LD+LVN Sbjct: 30 GAHLLLADRDEERLAAAVSRYSEGEAKAVGVVVDVTDPDQTKMMVDRCLAEFGALDILVN 89 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 449 AG++ + +A +D +++ ++RS++ AVPH+L + G GI+ Sbjct: 90 CAGLLTEVPLAEMDVATWDEMISVDLRSVFLCCRWAVPHMLAQGSGRIINISSQLGIKGG 149 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 G++ Y +KA V TR +A ELAP GV VN + PG + T L G++E+ + Sbjct: 150 VGLVHYCAAKAGVIGLTRALARELAPSGVLVNAIAPGPVWTPL--FAGITED-----WRQ 202 Query: 630 TKETH-ALGRPGKPDEVAATIAFLASDLASNI 722 KE LGR G P E+A T LASD N+ Sbjct: 203 AKEAELPLGRFGLPHEIAPTAVLLASDPGGNL 234 >UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Solibacter usitatus (strain Ellin6076) Length = 249 Score = 107 bits (257), Expect = 3e-22 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 1/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ +TGRN ++ + A + + +D T D++ + K + +GK+DVL N Sbjct: 30 GARVIVTGRNPATIKAAQAELGDNA--IVVPSDATSLPDMDALATKVKETFGKIDVLFVN 87 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG E + A YD ++N N + Y++ P L+ +++ P Sbjct: 88 AGYGHFVPFEAVTEAVYDEMLNLNAKGPYFIVQKLAP-LMPEGSSVVFTTSIANVKAVPT 146 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVI-LTELQRRGGLSEEQYAAFLERT 632 + AY +KA++ TR +A EL P+G+RVN V PG I T++ R G+ +E + Sbjct: 147 LSAYGAAKAALRAMTRSIAAELLPRGIRVNAVTPGPIGATDVMHRLGMPKEAQDQVYLQM 206 Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728 E+ + R G+P+E+A +AFLA D A+ TG Sbjct: 207 AESVPMKRLGRPEEIAKAVAFLAID-ATFTTG 237 >UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Sphingomonadaceae|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 266 Score = 107 bits (256), Expect = 4e-22 Identities = 67/188 (35%), Positives = 98/188 (52%), Gaps = 6/188 (3%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQ-----YDRLMNTN 347 I +L K +I+ +++KT DH+G +DVL NNA I ET + TS+ +D + N Sbjct: 61 IACNLRKAHEIKVLMQKTADHFGGIDVLHNNAAIHETDLTDKTSIEDLPEEIWDAVYEVN 120 Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELA 524 +++++ T AVP L SKG G S+P AY +K V T+ A++LA Sbjct: 121 LKALWLTTRYAVPWLKLSKGAAIVNVASTGSFVSYPQAGAYCATKGGVLLLTKATAVDLA 180 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 G+R NC PG I T + ++ + E A + H + R GKP+EVA FLAS Sbjct: 181 KYGIRCNCYCPGAIETPMLQKYLDAAEDKKAIMSVLTGAHLIPRLGKPEEVAKLACFLAS 240 Query: 705 DLASNITG 728 D +S I G Sbjct: 241 DDSSFING 248 >UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 248 Score = 106 bits (255), Expect = 5e-22 Identities = 69/216 (31%), Positives = 111/216 (51%), Gaps = 1/216 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L+ LGA + + R E+ Q+V++ + A + D+TKE + + + + I+ +G+LDV Sbjct: 26 LASLGAIVGVAARKDEDAQEVAEMIGE-AHAFPVQLDVTKELEWKTAVDEIINKFGRLDV 84 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGI 440 LVNNAG ++ + T+L Y +L+N N ++ +P + + KG Sbjct: 85 LVNNAGALKRKPFKETTLDDYQQLINVNQLGVFMGMQAVIPQMEKQQKGSIINNVSISAF 144 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 AY +K+SV ++ A+EL P G+RVN V+PG I T++ + E A+ Sbjct: 145 APISQSSAYAATKSSVVAMSKAAAIELGPAGIRVNMVHPGGIKTDMVTQ----TEDVPAY 200 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L R G+P E+A IAFLASD +S TG Sbjct: 201 YNSV----PLKRIGQPVEIAKAIAFLASDESSYCTG 232 >UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 296 Score = 106 bits (255), Expect = 5e-22 Identities = 68/220 (30%), Positives = 109/220 (49%), Gaps = 5/220 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST--LSITADLTKESDIEKIIKKTIDHYGKL 257 L+ GA +++ R V+ L++ + D L++ D+ E + +++++T++ G++ Sbjct: 65 LAAHGADVAVAARTVDELERTAADIRAATGRRCLAVPTDVKDEEQVIRLVRRTVEELGRI 124 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 434 DVLVNNAG G + + +D + NVR+ Y+ T A HL+ + G Sbjct: 125 DVLVNNAGGTRMGPLSSLPTRAWDASFDLNVRAAYFCTREAGRHLVAQRSGAIVNISSDA 184 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G+ G Y +KA++ FT A E GVR NC+ G + +E E Sbjct: 185 GLHGVRGGAHYASAKAALQMFTTVTAAEWGRYGVRANCLAVGPVASE-----RAVEAWRV 239 Query: 615 AFLERTKETHA--LGRPGKPDEVAATIAFLASDLASNITG 728 A ++ ++ A LGRPG P EVA + F ASD AS ITG Sbjct: 240 AGIDTSEFNTATPLGRPGTPAEVANAVLFFASDAASYITG 279 >UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Sphingobacteriales|Rep: Short-chain dehydrogenase/reductase SDR - Microscilla marina ATCC 23134 Length = 273 Score = 106 bits (255), Expect = 5e-22 Identities = 59/158 (37%), Positives = 84/158 (53%), Gaps = 1/158 (0%) Frame = +3 Query: 90 KLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266 K GA++ +TGRN E L KVS + + L I AD + ESD + ++K+TID YGK+DVL Sbjct: 30 KAGAKVVITGRNNEKLVKVSDMLNIEQIDNLPIVADSSVESDCKMVVKETIDKYGKIDVL 89 Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS 446 +NNAGI L+ +R+M N Y+T A+P+L +++G G R Sbjct: 90 INNAGISMRAMFAELDLSVIERVMQINFFGTVYITKFALPYLTQTQGSIVGVSSIAGFRG 149 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560 PG Y+ SK ++ F + EL K V V PG Sbjct: 150 LPGRTGYSASKFAMQGFLESLRTELLKKNVNVLVAAPG 187 >UniRef50_Q8YD94 Cluster: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE; n=10; Proteobacteria|Rep: TOLUENESULFONATE ZINC-INDEPENDENT ALCOHOL DEHYDROGENASE - Brucella melitensis Length = 262 Score = 106 bits (254), Expect = 6e-22 Identities = 68/220 (30%), Positives = 115/220 (52%), Gaps = 6/220 (2%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266 +K GA++ + R+ ++V+ + A L++ AD++KE+D++ ++ + +GK+D+L Sbjct: 36 AKGGAKVVIVDRDKAGAERVAGEIGDAA--LAVAADISKEADVDAAVEAALSKFGKVDIL 93 Query: 267 VNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXXG 437 VNNAGI + E ++DR++ NVR +Y +T +PH E +KG Sbjct: 94 VNNAGIGHKPQNAELVEPEEFDRIVGVNVRGVYLMTRKLIPHFKENGAKGQECVILNVAS 153 Query: 438 I---RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 R P + YN +K V T+ +A+ELAP +RV +NP + E E Sbjct: 154 TGAGRPRPNLAWYNATKGWVVSVTKALAIELAPAKIRVVALNP--VAGETPLLTTFMGED 211 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ +++ +GR KPD++A AFL S AS ITG Sbjct: 212 SEEIRKKFRDSIPMGRLLKPDDLAEAAAFLCSPQASMITG 251 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 106 bits (254), Expect = 6e-22 Identities = 71/220 (32%), Positives = 113/220 (51%), Gaps = 5/220 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE---KIIKKTIDHYGK 254 L+K GA L + N E+ + + + K +I T SD++ K I+ +D +G Sbjct: 26 LAKAGANLVIADLNEESSKATADEISKQTGVKAIGIG-TNVSDVDSAAKAIQACVDEFGS 84 Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXX 428 +D+LVNNAGI + + Q+D ++ N+ + T A+ ++++ G Sbjct: 85 VDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCTQAAIKFMMKNPNGGSIINLSS 144 Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 G+ G Y+ SKA V FT+ VALE+A + VR N + PG I TE+ + E+ Sbjct: 145 IAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVRCNAIAPGFIATEM--TDAIPEKI 202 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A + L R G+P+++A TIAFLASD++S ITG Sbjct: 203 RTAMVAAI----PLKRAGQPEDIANTIAFLASDISSFITG 238 >UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase precursor; n=2; Clostridium difficile|Rep: Probable short chain dehydrogenase precursor - Clostridium difficile (strain 630) Length = 245 Score = 106 bits (254), Expect = 6e-22 Identities = 62/191 (32%), Positives = 103/191 (53%), Gaps = 1/191 (0%) Frame = +3 Query: 159 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLM 338 +K S A+++ D+E ++ I +G LDVLVNNAG+ + + + +D +M Sbjct: 50 EKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMM 109 Query: 339 NTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515 N N++ +Y + +A+ +++ E KG GI + Y+I+KA + T+ +A Sbjct: 110 NINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK 169 Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695 E+ P +RVN + PGVI T++ G +EE A +E T L R G P+++A F Sbjct: 170 EVGPSNIRVNSIAPGVINTDM--LSGYNEEDIDALVEET----PLMRLGTPEDIANCAIF 223 Query: 696 LASDLASNITG 728 LASD ++ ITG Sbjct: 224 LASDKSNFITG 234 >UniRef50_P66781 Cluster: Uncharacterized oxidoreductase Rv1350/MT1393; n=19; Actinomycetales|Rep: Uncharacterized oxidoreductase Rv1350/MT1393 - Mycobacterium tuberculosis Length = 247 Score = 106 bits (254), Expect = 6e-22 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 1/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ L N+E + +K L++ D+T+ D++ +I+ ++ +G LDV+VNN Sbjct: 31 GARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGGLDVMVNN 90 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFP 452 AGI T+ + Q+D+++ +++ + T LA + E K G G Sbjct: 91 AGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMSSVSGKVGMV 150 Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632 G Y+ +KA + T+ A ELA G+RVN + PG+I R ++E ++ Sbjct: 151 GQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLI------RSAMTEAMPQRIWDQK 204 Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728 +GR G+P EVA+ FLASDL+S +TG Sbjct: 205 LAEVPMGRAGEPSEVASVAVFLASDLSSYMTG 236 >UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 255 Score = 105 bits (253), Expect = 8e-22 Identities = 61/186 (32%), Positives = 101/186 (54%), Gaps = 4/186 (2%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359 ++ D+T + I++++++TID YG++DVLVNN G+ G + + + +DR + N++S+ Sbjct: 55 ALLCDVTDPASIDRVVRETIDAYGRIDVLVNNVGVSAPGGVVDMTEEIWDRQFDINLKSV 114 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG--VLAYNISKASVDQFTRCVALELAPKG 533 + + +P + +G + G +AY+ SKA++ QFTR AL + Sbjct: 115 FLMCKAVLPLMDRQRGGNVVNVSSLSALRYSGKPQIAYSASKAALIQFTRMAALMHSEHN 174 Query: 534 VRVNCVNPGVILTELQRR--GGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 VR+NCV PG+I T L +R Y ++L+R L + G +VA AFLASD Sbjct: 175 VRLNCVIPGLITTPLVQRLAQQFGGGDYESYLKRRNAQVPLAQEGDAWDVANATAFLASD 234 Query: 708 LASNIT 725 A IT Sbjct: 235 EARYIT 240 >UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 262 Score = 105 bits (253), Expect = 8e-22 Identities = 61/215 (28%), Positives = 115/215 (53%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L++ GA + L N + ++ D A +++ D++ +++E ++K ++ +G++D+ Sbjct: 28 LAREGAHVVLADVNDNGGKSIAADLGPTA--MAVKCDVSSAAEVEALVKAAVERHGRIDI 85 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443 L NNAGI GT A+++R++ ++ S+YY A+PH+ G+ Sbjct: 86 LFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYACHFAIPHMPRGSA-IVNTASISGLG 144 Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623 AYN +K +V +TR +A++ G+RVN + PG++ T + G+ +Q Sbjct: 145 GDYRFAAYNAAKGAVVNYTRALAVDHGRDGIRVNALCPGLVETPI--TAGV--QQMPGLR 200 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E + + R +P+E+A+ +AFLASD AS +TG Sbjct: 201 EDWLKRIPMERAAQPEEMASVVAFLASDDASYVTG 235 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 105 bits (253), Expect = 8e-22 Identities = 65/219 (29%), Positives = 115/219 (52%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L+ GA++ + N E ++ K ++ + + AD++K D+EK + ++ YG++D Sbjct: 25 LASNGAKVVIVDFNKETGEETLKLVKEQGGEGIFVQADVSKSEDVEKYVNAAVETYGRID 84 Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXX 431 V NNAG+I+ + + ++YDR+M+ NV+ + +L + V ++E + G Sbjct: 85 VFFNNAGVIQKISPLTEIADSEYDRIMSINVKGV-FLGLKHVIKVMEGQGSGSIINTAST 143 Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 G+RS + Y+ SK +V T+ +LE KG+R+N + PG + T L E Sbjct: 144 AGVRSEHSMAVYSASKHAVIGLTKSASLEYVKKGIRINAICPGGVETALTNSVTAMFET- 202 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ +GR KP+E+A + FLASD AS +TG Sbjct: 203 GGYIPEEIPNMRMGRYAKPEELAEMVVFLASDKASYMTG 241 >UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR; n=13; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Arthrobacter sp. (strain FB24) Length = 297 Score = 105 bits (253), Expect = 8e-22 Identities = 68/180 (37%), Positives = 97/180 (53%), Gaps = 1/180 (0%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVRSIYYL 368 DL + +++ + G LD+LVNNAG + IE S Q+D + TNV ++++L Sbjct: 111 DLKDAAVCRELVDTAVRELGGLDILVNNAGKQVAQEDIEEISDEQFDHTLKTNVYAMFWL 170 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 T AVPHL + P ++ Y +KAS++ FT+ +A +LAPKG+RVN Sbjct: 171 TKAAVPHL-PAGSTIINTTSIQAYNPSPTLVDYATTKASINNFTKGLAQQLAPKGIRVNA 229 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 V PG I T LQ G +E A E K+T LGR G+P E+A FLAS +S + G Sbjct: 230 VAPGPIWTPLQVSSGQPKE---ALPEFGKDT-PLGRAGQPAELAPAYVFLASAESSYVVG 285 >UniRef50_Q982N5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=1; Mesorhizobium loti|Rep: 3-ketoacyl-acyl carrier protein reductase - Rhizobium loti (Mesorhizobium loti) Length = 256 Score = 105 bits (252), Expect = 1e-21 Identities = 66/184 (35%), Positives = 97/184 (52%), Gaps = 2/184 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 I D+++ D E + + +G+LD++V NAGI IENTS +DR+M N+R + Sbjct: 56 IGTDISQMRDAEASVALALKRHGRLDIIVQNAGIYPWQLIENTSTDDWDRVMAVNLRGTF 115 Query: 363 YLTMLA-VPHLLESKGXXXXXXXXXGIR-SFPGVLAYNISKASVDQFTRCVALELAPKGV 536 T A VP + G G + PG Y+ +KA ++ F R ALE + G+ Sbjct: 116 NATRAALVPMKAQRSGRMLYTSSITGPHVTSPGHGHYSATKAGINGFIRAAALEFSGYGI 175 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 VN V PG ILTE + + + AA+++ +++ LGR G P +VA FLASD A Sbjct: 176 TVNGVEPGNILTE-----AIQQHRGAAYIKNMEDSIPLGRLGSPRDVANAFLFLASDDAG 230 Query: 717 NITG 728 ITG Sbjct: 231 YITG 234 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 105 bits (252), Expect = 1e-21 Identities = 71/238 (29%), Positives = 115/238 (48%), Gaps = 2/238 (0%) Frame = +3 Query: 21 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 200 AGKV S+ GA L L RN Q ++++ + TL I AD+T Sbjct: 8 AGKVALISGITSGIGEATARLFSQQGASLVLVARNENKGQMLAEELNAQYPTLFIKADIT 67 Query: 201 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTML 377 + + ++++ ++T+ +G +D NNAGI I TS +++++NTN+ + + Sbjct: 68 QANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLNR 127 Query: 378 AVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554 + + + G + + P AYN S+ +V TR A+E A +GVRVN V Sbjct: 128 QLSIMSKQGHGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAAVEYAKQGVRVNAVA 187 Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 PG I T + R + Q A + + H +GR G+P EVA +L SDL+S + G Sbjct: 188 PGAIDTPIFERSTQKDPQLIA---KYHQAHPIGRIGQPREVAEAALWLCSDLSSFVVG 242 >UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Flavobacteriaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leeuwenhoekiella blandensis MED217 Length = 246 Score = 105 bits (252), Expect = 1e-21 Identities = 63/212 (29%), Positives = 111/212 (52%), Gaps = 1/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 G ++ + GRN E ++ + + + + I DL I K+I + + GK+DVLVNN Sbjct: 27 GYKVYIIGRNEEKTRQAADNLGELV--VPIVFDLNNLEAIPKLIDELLQATGKIDVLVNN 84 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR-SFP 452 AGI + A++DR+++TNV+S++ ++ V + + G + P Sbjct: 85 AGINMKKDFAEVTDAEFDRILHTNVKSVFAISREVVKSMKGNYGGSIVNISSMAAQYGIP 144 Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632 V+AY SK +++ TR +A++LA +RVNCV PG I T + + S++Q +R Sbjct: 145 QVIAYTASKTAIEGMTRAMAVDLAQYNIRVNCVAPGFIKTPMTAKALNSDKQRK---DRV 201 Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728 +G+ G P+++A + +LA + ITG Sbjct: 202 FSRTPMGKMGAPEDIADAVFYLAGKESKFITG 233 >UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 255 Score = 105 bits (252), Expect = 1e-21 Identities = 70/219 (31%), Positives = 116/219 (52%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA ++++GR+ E KV ++ L ITAD+T++ D++++ + I G LD Sbjct: 31 LAQAGATVAISGRSAERNAKVVEEAAAEGFALHPITADITRQDDVDRMTAEAISALGHLD 90 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 437 +LVNNAG + + Q+D + + NV++++ ++ A H+ E G G Sbjct: 91 ILVNNAGTCYHAESWDVTEEQWDSVFDLNVKALWACSLAAGAHMRERGSGSIVNIGSMSG 150 Query: 438 -IRSFPGVL-AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 I + P + AYN SKA+V T+ +A E P G+RVN + PG TE ++ Sbjct: 151 LIVNRPQMQPAYNASKAAVHHLTKSLAAEWGPLGIRVNALAPGYCKTE------MAPVDK 204 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F + + + R P+E+A ++ FLASD AS ITG Sbjct: 205 PEFKQHWIDDTPMLRYAMPEEIAPSVVFLASDAASFITG 243 >UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=4; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 245 Score = 105 bits (251), Expect = 1e-21 Identities = 73/219 (33%), Positives = 113/219 (51%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLT-GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKL 257 L+K GA + + R+ E +V + ++ T ++I AD++ ++ ++ KT++ YG++ Sbjct: 24 LAKEGATVVVNYARSAEAALEVVQRIEQQGGTAIAIAADVSVPEQVDTLVAKTVETYGRV 83 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434 DVLVNNAGI + SL + ++N N+ ++ T +L+ K G Sbjct: 84 DVLVNNAGITRDTLLLRMSLEDWQAVINLNLTGVFLCTRAVSKLMLKQKRGRIINIASVA 143 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G PG Y+ +KA V F++ VA ELA +G+ VN V PG I TE+ L E Sbjct: 144 GQMGNPGQANYSAAKAGVIGFSKTVAKELASRGITVNAVAPGFIATEMTAE--LKAEDIL 201 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASD-LASNITG 728 F+ LGR G+P EVA + FLA D A+ ITG Sbjct: 202 KFI-------PLGRYGEPTEVAGMVRFLALDPAAAYITG 233 >UniRef50_Q67QU0 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Symbiobacterium thermophilum|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Symbiobacterium thermophilum Length = 238 Score = 105 bits (251), Expect = 1e-21 Identities = 64/183 (34%), Positives = 97/183 (53%), Gaps = 1/183 (0%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + D+ + E + T+D +G++D+LVNNAG + +T+ A+++ L+ ++ +Y Sbjct: 51 LQVDVRDPAACEAAVSGTVDRFGRIDILVNNAGTALEKLLVDTTPAEWNDLVAVHLTGMY 110 Query: 363 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 T A+PH+L + G GI G +AY+ KA + FTR +A E+ P GV Sbjct: 111 ACTRAALPHMLSRRYGRIITISSIWGITGAAGEVAYSAVKAGQNGFTRALAQEVGPFGVT 170 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN V PG I TE+ L E+ +L R +GR G P+EVAA + FLA A Sbjct: 171 VNAVAPGAIDTEM--NSFLQGEELREWLSRV----PVGRLGTPEEVAALVRFLAGPQAGF 224 Query: 720 ITG 728 ITG Sbjct: 225 ITG 227 >UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 266 Score = 105 bits (251), Expect = 1e-21 Identities = 71/219 (32%), Positives = 110/219 (50%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + +T N E +++ + S+ +D +E+DI+ + D +G +D Sbjct: 37 LAEAGATVLITDINREAIEEAEHRLSSMKCKVKSLVSDAGREADIKSLFSYVADSFGGVD 96 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXX 434 +LVNNAGI I + SL Q+ ++ N+ S + + A ++ + G Sbjct: 97 ILVNNAGIYPATKILDMSLEQWREVIRINLESAFLCSQEAGRIMVRQGTGGVIVNISSMA 156 Query: 435 GIR-SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 ++ FPG+ Y SK V TR ALELAP +R V PG ILT R L + + Sbjct: 157 ALKPCFPGLAHYGASKGGVVNLTRSTALELAPHKIRAVAVVPGGILTG-GVRSNLKQSEE 215 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L+ T LG G+PD++A T+ FLASD A+ ITG Sbjct: 216 KDSLQSIGATIPLGGFGQPDDIARTVLFLASDSAAYITG 254 >UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 249 Score = 105 bits (251), Expect = 1e-21 Identities = 65/218 (29%), Positives = 112/218 (51%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L++ GA S+ +V +K + + ++ + + + D+T+ +++E ++++T + +G+LD+ Sbjct: 26 LAREGA--SVVAADVSGAEKETAEGNE--AIVPLHTDVTRAAEVEALVRETTERFGRLDI 81 Query: 264 LVNNAGI--IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437 L N G+ I + + +++D L+N N++S+ A+P ++ G G Sbjct: 82 LCNVVGVAGIAQAPVPDIEESEFDLLVNINLKSVLLGMKYAIPAMVAGGGGSIVNWSSVG 141 Query: 438 -IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 + S P Y +KA + TR A E GVRVN + PG + G E++Y Sbjct: 142 ALVSSPNTAVYGATKAGILSMTRAAAREWGRSGVRVNAICPGFVYPTGMTLMG--EKEYP 199 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 AL RPG PDE+AA AFLASD AS +TG Sbjct: 200 QAFRNASAKAALDRPGHPDEIAAVAAFLASDDASFMTG 237 >UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Desulfococcus oleovorans Hxd3 Length = 266 Score = 105 bits (251), Expect = 1e-21 Identities = 66/218 (30%), Positives = 114/218 (52%), Gaps = 7/218 (3%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA +++ R +ENL V+++ K L + A + + + I+++ + +G++D+LVN Sbjct: 35 GADVAIVSRKMENLAPVAEEIKAKGKRCLPVAAHVGRMDQLPAIVEQVVAEFGQIDILVN 94 Query: 273 NAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449 NA TI +D ++ N++ +Y+L+ AV ++E KG I F Sbjct: 95 NAATSPAYATIFEAQEKLWDSIIGLNLKGLYFLSQ-AVARVMEEKGAGGSIINVSSIDGF 153 Query: 450 PG---VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYA 614 V Y+ISKA V+ TR +ALELAP +RVN + PG T+L L E++ Sbjct: 154 APQAQVGIYSISKAGVNMATRSMALELAPHKIRVNAIAPGATRTKLFEGLFAFLPEDERE 213 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +++ + LGR PD++ + +LASD ++ +TG Sbjct: 214 KQIQQIGQAFPLGRVAVPDDMVGLMLYLASDASAYMTG 251 >UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 246 Score = 104 bits (250), Expect = 2e-21 Identities = 69/241 (28%), Positives = 112/241 (46%), Gaps = 2/241 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSIT 188 M GKV ++ GA +++ N+ + + + L++ Sbjct: 1 MRLKGKVAIVTGAGHGIGKATAIAFAREGAHVAVVDINMAGAEATVAEITRLDGRALAVQ 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 AD+++ + +E +++ + G++DVL+NNAGI + + Q+D ++N N++ ++ Sbjct: 61 ADVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLVKMTEQQWDAVINVNLKGVWLC 120 Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 PH+ + G G+ G Y +K V T+ A EL P GVRVN Sbjct: 121 ARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWARELGPSGVRVN 180 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 V PG I TE+ + E+ ERT L R GKP+EVAA FLASD +S +T Sbjct: 181 AVTPGFIATEMITT--IPEKVIQTVCERT----PLRRLGKPEEVAAVYVFLASDESSFMT 234 Query: 726 G 728 G Sbjct: 235 G 235 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 104 bits (250), Expect = 2e-21 Identities = 69/241 (28%), Positives = 119/241 (49%), Gaps = 3/241 (1%) Frame = +3 Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITA 191 N +GKV L++ GAQ+ ++ RN E +V+K+ ++ T+ I Sbjct: 8 NLSGKVAVITGSSKGIGKAIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLDTIGIAC 67 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYL 368 + KE + ++ KTI+ +G++D+LVNNA I G IE S +D++M+ NV++ + L Sbjct: 68 HIGKEDQRKNLVDKTIESFGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNVKAPWSL 127 Query: 369 TMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + L +PH +K G + G+ Y+ SKA++ T+ A E GV+ N Sbjct: 128 SNLVLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGKYGVKAN 187 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 + PG+I T+ +E+ L + ++ R G P+E+ LASD + +T Sbjct: 188 AICPGLIKTKFSAALWQNEK----ILSKVEKALPSSRMGMPEEMVGLACLLASDAGNYMT 243 Query: 726 G 728 G Sbjct: 244 G 244 >UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella pealeana ATCC 700345 Length = 262 Score = 104 bits (250), Expect = 2e-21 Identities = 69/216 (31%), Positives = 107/216 (49%), Gaps = 1/216 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLD 260 L+ GA++ + GRN L V + + + AD++ E+++ I++ YG LD Sbjct: 33 LAAEGAKVMICGRNQPPLDLVVAQIKQAGGVATAVIADVSNETELVAAIERCASEYGSLD 92 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 ++VNNA G+IE + T+V ++ T A+ + + G G Sbjct: 93 IMVNNAMAFTWGSIEEMDTQAWHENFKTSVDGTFWGTKAAMKLMKSNGGSIINLSSICGE 152 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 P + Y+ +KA+V F+R A E A +RVN V P V+ T G LS A Sbjct: 153 LGTPWMSGYSAAKAAVTNFSRAAAAEGAASNIRVNTVIPAVVETP-ATEGMLSN---ATA 208 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + T+ +GR G+PDE+A+ IAFLASD AS +TG Sbjct: 209 RKNTERLIPMGRVGQPDELASVIAFLASDEASYVTG 244 >UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|Rep: Glucose 1-dehydrogenase - Thermoplasma volcanium Length = 261 Score = 104 bits (250), Expect = 2e-21 Identities = 62/185 (33%), Positives = 96/185 (51%), Gaps = 6/185 (3%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D+T E ++++ ++KT YG++D+LVNNAGI + + T + R+++ NV Y + Sbjct: 53 DVTNEEEVKEAVEKTTKKYGRIDILVNNAGIEQYSPLHLTPTEIWRRIIDVNVNGSYLMA 112 Query: 372 MLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 +P +L G + AY SK ++ TR VA++ APK +R N Sbjct: 113 KYTIPVMLAIGHGSIINIASVQSYAATKNAAAYVTSKHALLGLTRSVAIDYAPK-IRCNA 171 Query: 549 VNPGVILTEL-----QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 V PG I+T + + G E +E H +GR G+P+EVA +AFLASD + Sbjct: 172 VCPGTIMTPMVIKAAKMEVGEDENAVERKIEEWGRQHPMGRIGRPEEVAEVVAFLASDRS 231 Query: 714 SNITG 728 S ITG Sbjct: 232 SFITG 236 >UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family member 2; n=64; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 2 - Homo sapiens (Human) Length = 258 Score = 104 bits (250), Expect = 2e-21 Identities = 66/217 (30%), Positives = 114/217 (52%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D Sbjct: 34 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 93 Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437 LV +AG+ G+ TS +D++++ NV+S L +P++ +G Sbjct: 94 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 153 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 + YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E + Sbjct: 154 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 213 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F KE H L R G+ ++ A ++FL S AS + G Sbjct: 214 F----KEHHQLQRIGESEDCAGIVSFLCSPDASYVNG 246 >UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=33; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Shewanella oneidensis Length = 254 Score = 104 bits (249), Expect = 3e-21 Identities = 61/184 (33%), Positives = 99/184 (53%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 ++I AD T+ I + I++T H G LD++VNNAGI+ +IEN +L ++R++NTNVRS Sbjct: 67 IAIKADSTEPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENLTLEDWERIVNTNVRS 126 Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 ++ + A H+ + F G Y +SK+++ + +A +L P+ + Sbjct: 127 VFVASQEAALHMNDGGRIINIGSTNAERIPFVGGAIYGMSKSALVGLAKGLARDLGPRAI 186 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 VN + PG + T++ G S E K LGR GK +E+A+ +AF+A A Sbjct: 187 TVNNIQPGPVDTDMNPDNGDSSEP-------IKAIGVLGRYGKAEEIASFVAFIAGPEAG 239 Query: 717 NITG 728 ITG Sbjct: 240 YITG 243 >UniRef50_Q89W00 Cluster: Blr0893 protein; n=7; Bradyrhizobiaceae|Rep: Blr0893 protein - Bradyrhizobium japonicum Length = 279 Score = 104 bits (249), Expect = 3e-21 Identities = 70/219 (31%), Positives = 112/219 (51%), Gaps = 8/219 (3%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ + GR + + ++K A+ + D+T E+ ++ +I +D +G++D L NN Sbjct: 30 GAKIVIAGRRLPEGEALAKQLG--ANCIFRQTDVTVEAQMQALIALAVDKFGRIDCLFNN 87 Query: 276 AG-IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG-IRS 446 AG +TG IE + ++D M T VRS+ A P++ + G G + Sbjct: 88 AGGPAQTGGIEGLEVERFDAAMATLVRSVMLGMKHAAPYMKKQGSGSIINNGSIAGRLAG 147 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRG-GL----SEEQY 611 F + Y +KA+V T+CVA+EL VRVN ++PG I T + + GL +E+ Sbjct: 148 FSSSVVYGAAKAAVIHLTKCVAMELGESNVRVNSISPGAIATGIFGKALGLATSAAEKTP 207 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A E K + R G PD++A FLASD +S I G Sbjct: 208 AVMREVYKTAQPIPRAGIPDDIAHAAVFLASDESSFING 246 >UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudomonas fluorescens (strain PfO-1) Length = 254 Score = 104 bits (249), Expect = 3e-21 Identities = 57/183 (31%), Positives = 99/183 (54%), Gaps = 1/183 (0%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + AD+T++ E+ + ++ +G+LD+LVNNAGII + + + ++R+ N + + Sbjct: 61 LVADITQDGAAERAVALAVEQFGRLDILVNNAGIIINKLVIDMTREDWERIQAVNATAAF 120 Query: 363 YLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 + AV ++ +K G +FP + AY SK ++ Q TR +ALE+ G+R Sbjct: 121 LHSREAVKAMMPNKSGSIVNIASYASYFAFPTIAAYTASKGALAQLTRTLALEVIGHGIR 180 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN V G ++T + + AFL + E +GR +P+E+A +AF+ASD AS Sbjct: 181 VNAVGVGDVVTNILNN---VVDDGPAFLAQHGEAAPIGRAAQPEEIAEVVAFIASDRASF 237 Query: 720 ITG 728 + G Sbjct: 238 MVG 240 >UniRef50_P95719 Cluster: Ata4 protein; n=2; Actinomycetales|Rep: Ata4 protein - Streptomyces capreolus Length = 256 Score = 104 bits (249), Expect = 3e-21 Identities = 64/188 (34%), Positives = 95/188 (50%), Gaps = 1/188 (0%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 A + + DL +E +++ ++ +G+LDVLV NAG + S +DR N Sbjct: 63 ARAVPVQGDLAREKACVAAVERVVESFGRLDVLVANAGRHRDALLLRLSEDDWDRHQEAN 122 Query: 348 VRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 ++S Y A+P +L + G G+ PG AY+ +KA + R VA E Sbjct: 123 LKSAYLCVRAALPSMLRQRHGRIVLVSSVAGLVGSPGQAAYSAAKAGLAGLARTVAHEHG 182 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 GV NCV PG+I + GLSE + L+RT A R G+P+EVAA +AFL+S Sbjct: 183 RYGVTCNCVAPGLI-ADTPSHDGLSEARRRQILDRT----AAQRAGRPEEVAAAVAFLSS 237 Query: 705 DLASNITG 728 A+ +TG Sbjct: 238 PAAAYVTG 245 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 104 bits (249), Expect = 3e-21 Identities = 70/217 (32%), Positives = 112/217 (51%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVE-NLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + L+ N E Q V++ + + D+T E+ + + +LD Sbjct: 26 LAREGATVYLSDMNEELGHQAVAEIRRQGGKAHFLHLDVTNENHWTGAVDTILAESDRLD 85 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXG 437 LVNNAGI+ +++TS ++DR+ NVRS++ T + + ++ KG G Sbjct: 86 ALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTRAVIEPMRKAHKGCIVNVSSIYG 145 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 + PG AY SK +V FT+ A++LAP +RVN V+PGVI T + ++ + + A Sbjct: 146 LVGAPGAAAYEASKGAVRLFTKACAVDLAPFNIRVNSVHPGVIATPMTQQILDAPQSARA 205 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L T LGR +P EV+ + FL SD AS + G Sbjct: 206 LLGPT----LLGRAAQPMEVSQAVLFLVSDEASFVHG 238 >UniRef50_Q5P686 Cluster: Subunit of 2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH; n=4; Proteobacteria|Rep: Subunit of 2-[hydroxy(Phenyl)methyl]-succinyl-CoA DH - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 248 Score = 103 bits (248), Expect = 3e-21 Identities = 60/201 (29%), Positives = 104/201 (51%), Gaps = 4/201 (1%) Frame = +3 Query: 138 QKVSKDCDKFAS----TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIE 305 +KV D+F+ L AD++ ++ ++ ++++T++ +G++D+LVNNAG+ G + Sbjct: 40 EKVRTTVDEFSRLGHRVLGTVADISNKAAVDGMVQQTVEAFGRIDILVNNAGMERAGALR 99 Query: 306 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKAS 485 S A +D ++ N++ + T H++E+K G Y+ +KA Sbjct: 100 KLSEADWDITVDVNLKGTFLCTQAVHGHMVENKHGRIVNIASRAWLGGAGQTPYSSAKAG 159 Query: 486 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGK 665 V TR +A+EL G+ VNCV PG+I T + L E+ L R G+ G+ Sbjct: 160 VVGMTRALAIELGRSGITVNCVAPGLIHTPMWEE--LPEKDRNFLLSR----QPTGKLGE 213 Query: 666 PDEVAATIAFLASDLASNITG 728 PD++A T+ FLA D +TG Sbjct: 214 PDDIANTLLFLADDDTGFVTG 234 >UniRef50_Q9JN17 Cluster: Yhg; n=6; Rhizobiaceae|Rep: Yhg - Agrobacterium tumefaciens Length = 258 Score = 103 bits (248), Expect = 3e-21 Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 3/183 (1%) Frame = +3 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 ADL ++K+ D G+LD+L+NNAGI G + Q+ ++ TNV ++++ Sbjct: 68 ADLKTREAACALVKRVADDAGRLDILINNAGIANGGDTPLFTEQQWRDVIATNVETVFWC 127 Query: 369 TMLAVPHLLE-SKGXXXXXXXXXGIRS-FP-GVLAYNISKASVDQFTRCVALELAPKGVR 539 + A+P + E +G GI S P +AYN SKA+V T+ +A ELA +R Sbjct: 128 SQAAIPVMREGGRGAIVNVGSMSGIVSNIPQNQVAYNSSKAAVHMMTKSLASELALDNIR 187 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN V PG I T++ R G + + +LE T + R G+PDE+A I FLAS+ +S Sbjct: 188 VNAVAPGYIDTDMSRGGMVHPVRGPIWLEMT----PMKRFGRPDEIATAILFLASEASSY 243 Query: 720 ITG 728 +TG Sbjct: 244 VTG 246 >UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma proteobacterium HTCC2207|Rep: Putative dehydrogenase - gamma proteobacterium HTCC2207 Length = 259 Score = 103 bits (248), Expect = 3e-21 Identities = 60/169 (35%), Positives = 92/169 (54%), Gaps = 7/169 (4%) Frame = +3 Query: 243 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-----G 407 H+ LD++VN AG+ GTIE L +D+ M N+RS + A+ + + G Sbjct: 79 HFSGLDIMVNVAGVTLMGTIEELDLETWDKTMAINLRSCFLGCQGAIKLMKSNSAESHGG 138 Query: 408 XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG--VRVNCVNPGVILTELQ 581 +++ P ++AYN SKA VD T+ VAL A G + VN +NPGVI T++ Sbjct: 139 SIINMASVSAVKAKPELVAYNASKAGVDMMTKSVALHCAVSGYGINVNSINPGVIETDML 198 Query: 582 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ E A ++ + H +GR G+P++VAA +LASD AS +TG Sbjct: 199 KKVMSQVEDGDALMDSYRALHPIGRIGQPEDVAAMAVYLASDDASFVTG 247 >UniRef50_Q0AZ76 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family precursor; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Oxidoreductase, short chain dehydrogenase/reductase family precursor - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 252 Score = 103 bits (248), Expect = 3e-21 Identities = 73/241 (30%), Positives = 116/241 (48%), Gaps = 2/241 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSIT 188 M GKV L+ GA++ + GR E L + V ++ L+I Sbjct: 1 MKLKGKVAVITGGGTGIGRAAAIALAAEGARVVVMGRRPEPLNETVDIVKERGGEGLAIP 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 +D+TK DIEK + + YG+LD+LVNNAG TSL +DR+ ++RS++ + Sbjct: 61 SDVTKIEDIEKARDEVRETYGRLDILVNNAGSALFKPFMKTSLEDFDRIYQVDLRSVFAV 120 Query: 369 TMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + L +P +LE G G+ AY K V Q TR +A EL P+ +RVN Sbjct: 121 SQLMLPLMLEGGGGSIINIASILGVLGGKSSSAYCAMKGGVVQLTRALAAELGPE-IRVN 179 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 C+ P I+T + LS + +++ + + R P+++ +I F ASD + +T Sbjct: 180 CLCPSHIITPMM-EDELSRIESKGKMDKLTKMFPMKRLAYPEDMTGSILFYASDDSKWLT 238 Query: 726 G 728 G Sbjct: 239 G 239 >UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member 10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 10 - Homo sapiens (Human) Length = 270 Score = 103 bits (248), Expect = 3e-21 Identities = 64/183 (34%), Positives = 95/183 (51%), Gaps = 1/183 (0%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 359 I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+ Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VNC++PG I T L A + LGR G+P EV A FLAS+ A+ Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237 Query: 720 ITG 728 TG Sbjct: 238 CTG 240 >UniRef50_Q5FPE5 Cluster: NAD(P)-dependent glucose 1-dehydrogenase; n=1; Gluconobacter oxydans|Rep: NAD(P)-dependent glucose 1-dehydrogenase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 266 Score = 103 bits (247), Expect = 4e-21 Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 4/241 (1%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS--ITA 191 FAGK V ++ GAQ++L GR + L V + K + T Sbjct: 9 FAGKKVLVTGASQGIGEATALRFAEEGAQVALNGRKEDKLIAVREKLPKVSGGEHPIATG 68 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D++KE D+++++ ++I G LDVLV NAG E+ L ++ +M NV + Sbjct: 69 DISKEDDVKRLVAESIKAMGGLDVLVCNAGYQIPSPSEDIKLEDFEGVMAVNVTGVMLPC 128 Query: 372 MLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + + LE+ KG I P L Y+ SK +V R +ALE A +G+RVN Sbjct: 129 REVIRYWLENGIKGTIIVNSSVHQIIPKPHYLGYSASKGAVGNIVRTLALEYATRGIRVN 188 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 V PG I+T + EQY A + RPG+ E+A I FLA++ ++ IT Sbjct: 189 AVAPGAIVTPINMSWIDDPEQYKAVSSHI----PMKRPGESREIADAITFLAAEDSTYIT 244 Query: 726 G 728 G Sbjct: 245 G 245 >UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain MCS) Length = 266 Score = 103 bits (247), Expect = 4e-21 Identities = 70/213 (32%), Positives = 108/213 (50%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA+L +T E L ++ + + + + D++ E D ++I +D +G+LDVLV Sbjct: 43 GARLVVTDIQSEPLLALADELRHAGADVEPVVGDVSVEYDAGRMIGAAVDRFGRLDVLVA 102 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSF 449 NAGII G + A +D +M + R ++ A+ +L + G G+ Sbjct: 103 NAGIIPLGDALEMTAAGWDEVMAIDGRGMFLCCKFAIEAMLPTGGGAIVCLSSISGLAGQ 162 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 AY +K T+ +A+E A +G+RVN V PG I TE +R E + +L Sbjct: 163 KRQAAYGPAKFIATGLTKHLAVEWADRGIRVNAVAPGTIRTERVKRFP-EEPGGSEYLAA 221 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + H +GR G+P EVA+ I FLASD AS ITG Sbjct: 222 VERMHPMGRIGEPAEVASAIVFLASDDASFITG 254 >UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Rep: Dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 254 Score = 103 bits (247), Expect = 4e-21 Identities = 61/214 (28%), Positives = 111/214 (51%), Gaps = 3/214 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 G ++++ + +K ++ DK + L + D++ ES +E ++K +G++D+LVN Sbjct: 35 GMKVAILSVGEGSAKKAAESIDKSGTGALGLQCDVSDESSVELALEKINSLFGRIDILVN 94 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR--S 446 +AGI++ +IE + +D++++TN+R + ++ +L +SK R Sbjct: 95 SAGILDMSSIEEMTTEHWDKVLSTNLRGTFTTIQKSIKYLEKSKFPRIINISSNSGRMGG 154 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626 F +AY+ SK + T +A +LAPKG+ VNC+ PG I G +S ++ L Sbjct: 155 FENGMAYSASKGGIIALTYGLARKLAPKGITVNCIAPGTI------EGDMSAQRSQETLN 208 Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + +GR G P+EVAA + A D + TG Sbjct: 209 NLLKRFPIGRFGTPEEVAAAALYYAGDDSGFTTG 242 >UniRef50_A3ZX88 Cluster: Putative dehydrogenase; n=1; Blastopirellula marina DSM 3645|Rep: Putative dehydrogenase - Blastopirellula marina DSM 3645 Length = 251 Score = 103 bits (247), Expect = 4e-21 Identities = 68/216 (31%), Positives = 107/216 (49%), Gaps = 5/216 (2%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GAQ+ L RN E L + + +S ADL+ E++ + + ++DVLVN Sbjct: 24 GAQVWLVARNAEKLATAADSLQSAGTKVMSTVADLSDPGAAEQVGVEVAATWDRVDVLVN 83 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452 NAG+ + + + + N+ S Y LT +P L ++G R P Sbjct: 84 NAGMARFTSFSEATPDEIQAQVQLNLLSPYLLTQQLLPLLAAAQGNVINISSTSAHRLIP 143 Query: 453 GVLA--YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYAAF 620 G A Y ++K ++ T+ +ALEL P+GVRVN + PG I T L ++ +EE+ + Sbjct: 144 GRPASVYAMTKGGLNSLTKALALELGPQGVRVNAIAPGTIKTPLTQKMIASFTEERKKEY 203 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + ++ ALGR G+P+EVA +LAS A TG Sbjct: 204 DQFVRQAFALGRLGEPEEVAHLAVYLASVEAKWTTG 239 >UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Planctomycetaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Blastopirellula marina DSM 3645 Length = 256 Score = 103 bits (247), Expect = 4e-21 Identities = 62/217 (28%), Positives = 110/217 (50%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLD 260 ++ GA++++ RN E L + + + D+TK +E ++ ++ + KLD Sbjct: 35 MASRGAKVAVVARNAEKLADTVAIIEAAGGVAQAYSCDVTKRESVEAVVDAVMEKWEKLD 94 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437 VLVNNAG+ + + ++D ++ TN+R ++ T A ++ ++ G G Sbjct: 95 VLVNNAGVTRDNLLPVMTDDEWDNVIETNLRGMFLFTRAASKQMMRARFGRIINISSVSG 154 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 + PG Y+ SKA + FTR ++ EL + V VN + PG I +++ + G A Sbjct: 155 LMGNPGQTNYSASKAGMIGFTRSLSRELGKRKVTVNAICPGFIESDMTKALG------PA 208 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ K+ R GKP+E+A + FLAS A+ ITG Sbjct: 209 VMDEVKKRIPAQRMGKPEEIADGVLFLASPQAAYITG 245 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 103 bits (247), Expect = 4e-21 Identities = 69/215 (32%), Positives = 112/215 (52%), Gaps = 4/215 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA + + N E L + +D +F +S + D+TK +++ ++ + +YG LDV++N Sbjct: 48 GANVVMADVNAEKLAESVQDLIEFDGAVSSMVCDVTKRENLQALVGLAVSNYGNLDVMIN 107 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESK-GXXXXXXXXXGIRS 446 NAGI + S +YD +M+ N+R + T +A ++ + K G + + Sbjct: 108 NAGIAKVQDFLEISDDEYDAVMDVNLRGAFIGTQIAGKQMIAQGKGGVIINMSSINALVA 167 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL-SEEQYAAFL 623 P + Y ISK ++Q T A+ LAP +RV + PG ILT++ + S E L Sbjct: 168 NPMLSTYAISKGGMNQLTNIAAVGLAPHNIRVCGIGPGTILTDMVADVIMTSPEARHNVL 227 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 RT + R G+P E+A+ AFLASD AS +TG Sbjct: 228 SRT----PMERCGEPREIASVAAFLASDDASYMTG 258 >UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 265 Score = 103 bits (247), Expect = 4e-21 Identities = 70/238 (29%), Positives = 114/238 (47%), Gaps = 2/238 (0%) Frame = +3 Query: 21 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADL 197 AGKV + GAQ+ + + E Q + ++ A L + AD+ Sbjct: 14 AGKVALITGAGSGIGRATALLFATEGAQIVVCDLDPEGGQATVRAIEQAGAQALFVQADV 73 Query: 198 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 377 + +D + +++T+ H+ +LDVL NNAGI + +TS A +D +M NV+SI+ ++ Sbjct: 74 AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133 Query: 378 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554 AVP + E G G+ ++Y +K +V TR +AL+ P+ +RVN V Sbjct: 134 AVPVMAEQGGGSIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMALDHGPQRIRVNSVC 193 Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 PG T + R L + L R G+ +E+A + FLASD +S +TG Sbjct: 194 PGDTDTAMLRDEARQLGLPETALVLAGNSRPLMRVGRAEEIAQVVLFLASDRSSFVTG 251 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 103 bits (247), Expect = 4e-21 Identities = 72/240 (30%), Positives = 115/240 (47%), Gaps = 1/240 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 MN GKV L++ GA++ T + Q +S +++ Sbjct: 1 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMAL-- 58 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 ++T IE ++K D +G +D+LVNNAGI + ++ +M TN+ SI+ L+ Sbjct: 59 NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLS 118 Query: 372 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 + +++ + G G G Y +KA V FT+ +A E+A +GV VN Sbjct: 119 KAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNT 178 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 V PG I T++ + L++EQ A L + GR G P E+A+ +AFLAS A+ ITG Sbjct: 179 VAPGFIETDMTK--ALNDEQRTATLAQV----PAGRLGDPREIASAVAFLASPEAAYITG 232 >UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 253 Score = 103 bits (246), Expect = 6e-21 Identities = 61/182 (33%), Positives = 96/182 (52%), Gaps = 3/182 (1%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYL 368 D+++E D ++I T+ +G+LD++V NAGI + +E+ S+ Q+ ++++ N+ ++ Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125 Query: 369 TMLAVPHLLE--SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542 LA+ + + + G G PG +YN +K V TR + + A G+RV Sbjct: 126 NKLAIVQMKKQGTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLGVSHAQDGIRV 185 Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722 N V PG + T L R +EE A R H +GR G DEVA + FLASD AS I Sbjct: 186 NAVCPGFVATPLIERA--TEEARA----RLVAAHPIGRLGHADEVAKAVLFLASDDASFI 239 Query: 723 TG 728 G Sbjct: 240 VG 241 >UniRef50_Q5V8A5 Cluster: LtxD; n=2; Bacteria|Rep: LtxD - Lyngbya majuscula Length = 246 Score = 103 bits (246), Expect = 6e-21 Identities = 62/183 (33%), Positives = 99/183 (54%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359 ++ DL + +DIE++ + T + +LD+LVN+A ++TG+IE+ S+ + R+ N + Sbjct: 60 AMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFSIHDWQRVFAVN-STA 118 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 +LT+ L + G + + PG+ AY SK S++Q TR A ELA +G+ Sbjct: 119 PFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQLTRVAAWELADRGIT 178 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN V+PG T+L R G E LE+ LGR G+P ++A +AFL + Sbjct: 179 VNSVSPGPTDTDLLRTGNPPE-----VLEQAIAMTPLGRLGQPKDIADVVAFLVGNDGRW 233 Query: 720 ITG 728 ITG Sbjct: 234 ITG 236 >UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteobacteria|Rep: Short chain dehydrogenase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 278 Score = 103 bits (246), Expect = 6e-21 Identities = 76/219 (34%), Positives = 107/219 (48%), Gaps = 8/219 (3%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 G +++++GR E ++ + + + AD+ E+D+ ++++T+ +G++DV VN Sbjct: 56 GYRVAVSGRREEAGNALAAELRALGNEAEFLLADVRFEADVRNLVEQTVVRFGRIDVAVN 115 Query: 273 NAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPH-----LLESKGXXXXXXXXX 434 NAG + I S A Y NV TML++ H L + G Sbjct: 116 NAGTEGQLAPIVEQSAANYAETFGVNVLG----TMLSLKHEMRVMLAQGSGSIINLSSVA 171 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE-LQRRGGLSEEQY 611 G G Y SK +V+ T+ ALE A GVRVN V PG + TE L R G SEE Sbjct: 172 GKVGIAGASVYVASKHAVEGLTKSAALEGAAAGVRVNAVAPGPVATEMLDRFVGGSEENK 231 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A FL T GR PDE+A TI FLASD S +TG Sbjct: 232 AGFL----ATIPAGRAATPDEIAQTIVFLASDKVSYLTG 266 >UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas naphthalenivorans (strain CJ2) Length = 286 Score = 103 bits (246), Expect = 6e-21 Identities = 67/196 (34%), Positives = 100/196 (51%), Gaps = 12/196 (6%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTNVR 353 L + D+T E +E + ++ +G++D LVNNAGI +TG S+ +DR++ ++R Sbjct: 68 LGLGCDVTSEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLR 127 Query: 354 SIYYLTMLAVPHLLES-------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 512 + ++ H+L++ +G P AY+ KA V TR +A Sbjct: 128 GTFLMSRAVARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA 187 Query: 513 LELAPKGVRVNCVNPGVILT----ELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVA 680 E A G+RVN V PG + T EL+R+G + AA RT LGR +P E+A Sbjct: 188 SEWARAGIRVNAVAPGYVRTALVAELERKGAIDA---AAIRRRT----PLGRMAEPAEIA 240 Query: 681 ATIAFLASDLASNITG 728 IAFLASD AS +TG Sbjct: 241 EVIAFLASDRASYVTG 256 >UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13; n=4; Bilateria|Rep: Dehydrogenases, short chain protein 13 - Caenorhabditis elegans Length = 257 Score = 103 bits (246), Expect = 6e-21 Identities = 71/218 (32%), Positives = 114/218 (52%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L GA + + R EN+ + V+ + TA + +SD K+I T+D + KLD Sbjct: 31 LGAAGASVVVCSRKKENVDEAVAALRLENIDAHGTTAHVGNKSDRTKLIDFTLDRFTKLD 90 Query: 261 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXX 434 +LV+NA + G + + +Q+D+L++ NV+S + LT AVPHL S +G Sbjct: 91 ILVSNAAVNPHYGDLMKVTDSQWDKLLDLNVKSAFELTKEAVPHLEASGRGNVVFVSSVA 150 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G + AY++ K ++ ++ +AL LA + +RVN + PG+I T+ + E + Sbjct: 151 GYSPMNEIGAYSVMKTTLTGLSKSLALNLARRNIRVNSIAPGIIQTDFSQVLFSDESEKQ 210 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +L + A R G PDE A +AFL SD AS I+G Sbjct: 211 KWLSQI----AQRRFGDPDECAEAVAFLVSDEASYISG 244 >UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1; Terrabacter sp. DBF63|Rep: Short-chain dehydrogenase/redutase - Terrabacter sp. DBF63 Length = 252 Score = 102 bits (245), Expect = 8e-21 Identities = 59/184 (32%), Positives = 96/184 (52%), Gaps = 2/184 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG-TIENTSLAQYDRLMNTNVRSI 359 + AD+T + ++ +++ +D YG+LD+ NNAGI TG + + ++ Q+D+++ N+ + Sbjct: 60 VRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTGV 119 Query: 360 YYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 + +P +L + G G + AY SK V TR A+E + KG+ Sbjct: 120 FISMKAEIPQMLAQGGGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAAVEYSDKGI 179 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 RVN V PGVI T + EE Y F + H +GR G P ++A +A+L SD A+ Sbjct: 180 RVNAVLPGVIQTPMI---DALEETYPGFKDALLTKHPIGRLGTPHDIAEMVAWLGSDAAA 236 Query: 717 NITG 728 TG Sbjct: 237 FATG 240 >UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB18) Length = 254 Score = 102 bits (245), Expect = 8e-21 Identities = 62/187 (33%), Positives = 90/187 (48%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 A +++ D++ D ++ + + +G++DVLVN AG+ E E T LA + +TN Sbjct: 64 AQGIAVAGDISNSEDARAMVGEVVARFGRIDVLVNCAGVAEYRAFEATDLAMFRATFDTN 123 Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527 V + A+PHL G R P Y SKA+V T +A E P Sbjct: 124 VFGTVAMIQAALPHLTAPGGRIINFSSALATRPIPTASIYAASKAAVSALTHALAKEFGP 183 Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 +G+ VN + PGVI TE+ + E+ AA K LGR G+ D+VA FLAS Sbjct: 184 RGITVNAIAPGVIETEM--TAAILAERGAAI----KAMTPLGRIGQTDDVAGLALFLASH 237 Query: 708 LASNITG 728 A +TG Sbjct: 238 DAGWLTG 244 >UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia metallidurans CH34|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) Length = 269 Score = 102 bits (245), Expect = 8e-21 Identities = 68/223 (30%), Positives = 122/223 (54%), Gaps = 9/223 (4%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 ++LGA++ + R+ + + + + + + D+ +E++I ++ + +H+G +DV Sbjct: 36 ARLGARVCVVDRDAASAAETTALIRAEGGAAETFVGDVAEEAEIARLFAEAREHFGPIDV 95 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGI 440 L +N GI +TG + +T + +D N NVRS+ + +P ++E +G G+ Sbjct: 96 LHHNVGIGKTGGVLDTDVRDFDAAHNVNVRSLLLASQQVLPSMVERGRGAIVTVSSVAGL 155 Query: 441 R--SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 R +P L+Y++SKA++ QFTR +A + A G+R NCV PG+I + R +Q++ Sbjct: 156 RYIGYPH-LSYSVSKAALIQFTRMIAQQYAGSGIRANCVVPGLI--DTPRIAHTVAKQFS 212 Query: 615 A-FLERTKETHA----LGRPGKPDEVAATIAFLASDLASNITG 728 A L+ + A + R G +VA AFLASD A+ ITG Sbjct: 213 ADSLDDARAARARQVPMQRMGTAWDVAHACAFLASDAAAYITG 255 >UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 282 Score = 102 bits (245), Expect = 8e-21 Identities = 65/240 (27%), Positives = 117/240 (48%), Gaps = 3/240 (1%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITAD 194 F GKV ++ GAQ+++T R E L+++ + + + ++I D Sbjct: 38 FNGKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRCD 97 Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLT 371 ++ D+ + +T++ +G+LD NNAG+ + + +L ++DR+++ N+R + Sbjct: 98 VSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTFVCM 157 Query: 372 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 + +L + G GIR G +Y SK ++ T+ AL+ A +RVN Sbjct: 158 KHEIAQMLRQGGGVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAALDYAKANIRVNA 217 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 V PG I T + R + Q A LE +GR GKP+E+A + ++ SDL + +TG Sbjct: 218 VLPGNIETPMMERFTGGDIQKAIDLE------PVGRLGKPEEIAEAVLWMCSDLGAFVTG 271 >UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 259 Score = 102 bits (245), Expect = 8e-21 Identities = 68/218 (31%), Positives = 104/218 (47%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 ++ GA L LT N + ++ + + + ++ D+T+ D E+ + +D +G LD Sbjct: 30 MAAAGASLVLTDINHSAVAALADELGREGTQAAALQHDVTQPGDWERAVALAVDTFGGLD 89 Query: 261 VLVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXX 434 +LVNNAGI T + N L + +++ N+ ++ + P L G Sbjct: 90 ILVNNAGIAGDNTDLMNLDLENWHSVLSVNLDGVFLGLRYSGPALERRGGGSVINISSIL 149 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G FPG Y SK +V ++ ALE AP +RVN V+PG + T L R E A Sbjct: 150 GKVGFPGAAPYCASKGAVTLLSKSAALEWAPLKIRVNSVHPGFVETPLVRDALAEREDGA 209 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E H +GR G E+A + FLASD AS +TG Sbjct: 210 EMAELLVAAHPIGRLGLATEIANAVTFLASDEASFMTG 247 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 102 bits (245), Expect = 8e-21 Identities = 67/242 (27%), Positives = 114/242 (47%), Gaps = 3/242 (1%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSIT 188 MNF +VV ++ GA+L+L NV L + + ++ S Sbjct: 2 MNFKDQVVLITGASGGLGKEAAKQFAQQGAKLALCDLNVAALNDLGTELIEQGYEVFSQP 61 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYY 365 D++ E +++ I T H+G+LDV +NNAGI + T+ + ++R+M+ NV+ +Y Sbjct: 62 CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121 Query: 366 LTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542 +PH++ + G GI P + AY SK +V T+ VA E G+RV Sbjct: 122 CMKYQIPHMIKQGGGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVAHEYGRAGIRV 181 Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722 N V P + +T++ + + + L + + AL R +P+EVA + F S + Sbjct: 182 NSVCPYITMTDMVEQHLKTLDNREEVLAKYSKASALRRVAQPNEVAKVMLFACDKNNSYM 241 Query: 723 TG 728 TG Sbjct: 242 TG 243 >UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Roseovarius sp. 217 Length = 256 Score = 102 bits (245), Expect = 8e-21 Identities = 66/220 (30%), Positives = 112/220 (50%), Gaps = 4/220 (1%) Frame = +3 Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 FLS+ GA+++L +V++L + D L+I AD++ D ++ + +T++ +G++D Sbjct: 26 FLSE-GAKVALVDLHVDDLSDAAGDLGNPDDLLTIAADVSSVEDCKRYVAQTVEKFGRID 84 Query: 261 VLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 434 V NNAG+ + + + +DR+M NVR + +P + + G Sbjct: 85 VFFNNAGVEGMVAPLVDQKIEDFDRVMAVNVRGAFLGLQHVLPVMTGQQSGSVINMSSIA 144 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR--RGGLSEEQ 608 G++ P V Y SK +V TR A+E+A VRVN V+P + T + R G + Sbjct: 145 GLKGSPNVAPYITSKHAVVGLTRAAAIEVAGHNVRVNSVHPSPVNTRMMRSLEEGFNPGH 204 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ T LGR G+ E+A + FLASD ++ ITG Sbjct: 205 GDEVKQQLAGTIPLGRYGESIEIANLVLFLASDESAFITG 244 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 102 bits (244), Expect = 1e-20 Identities = 65/218 (29%), Positives = 108/218 (49%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257 ++K G + L N E +++ + D K TL ++ ++TK D + +I + +GKL Sbjct: 33 IAKEGGDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSCNVTKPEDCDSVIAGVKEKFGKL 92 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434 D LVNNAG+++ S ++D +++ N++ ++ +T A LL+++ G Sbjct: 93 DFLVNNAGVLKDNLFIRMSEQEFDFVLDVNLKGVFLMTKYASKLLLKAESGRIVNISSVS 152 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G+ PG Y+ SKA V T+ A E A + V VN V PG + T++ L EE Sbjct: 153 GLTGQPGQANYSSSKAGVIALTKVAAREFAGRNVLVNAVCPGYVQTDM--TASLPEEVQK 210 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + L RPG E+A + F SD ++ ITG Sbjct: 211 KLTD--PAFIPLRRPGTQQEIANAVKFFLSDQSNYITG 246 >UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 268 Score = 102 bits (244), Expect = 1e-20 Identities = 64/219 (29%), Positives = 111/219 (50%), Gaps = 8/219 (3%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GAQ+ RN ++ +K D+ + TAD+++ ++IE ++ + YG++DVL N Sbjct: 35 GAQVFCVDRNGTAAEETAKIINDEGGKATAFTADVSRSAEIEAMVAACLKAYGRIDVLDN 94 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452 N GI E G++ + +DR+ + N++S Y+ +P ++E G Sbjct: 95 NVGIAEMGSVVEVTEESWDRVFSVNLKSAYFAMKHVIPVMVEQGGGSIINISSIASIRHM 154 Query: 453 GV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQYAAFL 623 G+ + Y SKA+++Q TR A+E A VRVN + PG++ T + + GL+ + Sbjct: 155 GISYVTYGTSKAAMNQMTRTTAIEFARHHVRVNAILPGLMKTPMVEHSAGLAASYAKGDV 214 Query: 624 E---RTKETHA-LGRPGKPDEVAATIAFLASDLASNITG 728 E R ++ +G G +VA FLASD + +TG Sbjct: 215 EAMWRARDAQVPMGHMGDAFDVANAALFLASDESKYVTG 253 >UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 306 Score = 102 bits (244), Expect = 1e-20 Identities = 68/188 (36%), Positives = 96/188 (51%), Gaps = 4/188 (2%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLA---QYDRLMNTN 347 +++ D+T DIE++I +D +GKLDVL NNAG TG I + A +D +M N Sbjct: 114 IAVHVDVTSTEDIERMITTAVDRFGKLDVLYNNAGF--TGPIVPLAEAGEDYFDAVMAVN 171 Query: 348 VRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 V+ +Y A+P +L G G+ + G+ Y +K +V Q TR AL+ A Sbjct: 172 VKGVYLGMKAAIPVMLAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAALDYA 231 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 KG+RVN V PG T R+ ++ E + R G PDE+AA FLAS Sbjct: 232 AKGIRVNAVCPGATWT---RQADAEDDSLPP--EGVVPPQPMRRWGMPDELAAAALFLAS 286 Query: 705 DLASNITG 728 D AS +TG Sbjct: 287 DDASFVTG 294 >UniRef50_Q333V8 Cluster: NAD or NADP oxidoreductase; n=1; Micromonospora sp. ML1|Rep: NAD or NADP oxidoreductase - Micromonospora sp. ML1 Length = 264 Score = 102 bits (244), Expect = 1e-20 Identities = 68/211 (32%), Positives = 103/211 (48%), Gaps = 1/211 (0%) Frame = +3 Query: 99 AQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNA 278 A + GR L++++ D +T + AD+T+ E ++ +G + LVNNA Sbjct: 46 ANVVAVGRREAALRELTGDGGGQVAT--VAADITEPGAAEHVVAAATTRFGTVHGLVNNA 103 Query: 279 GIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGV 458 G+ T++ S +DRL+ TNVR+ L A+PHL E +G + + PG Sbjct: 104 GLARFATLDTASDEDFDRLLATNVRAPAALIRAALPHLREHRGAVVNVSSVGAVLAMPGR 163 Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKE 638 Y SKA+++ TR +A ELAP VRVN V PG + T + GL + A Sbjct: 164 SFYGASKAALNSLTRSLARELAP-DVRVNAVLPGPVDTPMWDDMGLDSVKSALLRSSLLA 222 Query: 639 THALGRPGKPDEVAATI-AFLASDLASNITG 728 LGR G+P E+A + L + + ITG Sbjct: 223 ATPLGRFGQPAEIAGWVCGLLDPEFSGWITG 253 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 102 bits (244), Expect = 1e-20 Identities = 71/217 (32%), Positives = 110/217 (50%), Gaps = 3/217 (1%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 263 +K GA++ +T N ++ + D F L + D++ E D +K+ + I + K+D+ Sbjct: 29 AKEGAKIVITDINEQSGNETVSDIQAFGGEALFVLHDVSNEDDWKKVADEAIHTFNKVDI 88 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXG 437 L NNAGI + L+ ++RLM+ NV + +L M + L+ ++KG G Sbjct: 89 LFNNAGIYIIKPLAEIELSDWNRLMSINVTGV-FLGMKHIMPLMAKQNKGSVINASSIAG 147 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 + G + Y SK +V T+ A+E AP GVRVN ++PG I T + S ++ Sbjct: 148 LTGAAGHVLYGASKGAVRIMTKDAAMEYAPYGVRVNSIHPGYIDTGMADYA--SATTGSS 205 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E K LGR G EVA T+ FLASD +S TG Sbjct: 206 KDELGKNLFPLGRLGSVKEVAQTVLFLASDESSFSTG 242 >UniRef50_Q7CHM2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=8; Yersinia|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Yersinia pestis Length = 248 Score = 101 bits (243), Expect = 1e-20 Identities = 69/218 (31%), Positives = 107/218 (49%), Gaps = 4/218 (1%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 S++G + +GR E + + D + L + AD+ ESDI+ +I+ T++ +G LDV Sbjct: 23 SEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDV 82 Query: 264 LVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXG 437 VN AG + ET I+ + + + NTNV +P ++E KG G Sbjct: 83 AVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAG 142 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-QRRGGLSEEQYA 614 + P Y SK +++ T+ ALE+A GVR+N ++PG + ++ R G E Sbjct: 143 LVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKK 202 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 AF+E R +EVA TI FLA D + ITG Sbjct: 203 AFIEMMPNK----RFTTQEEVAHTIVFLAEDNVTAITG 236 >UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Burkholderiales|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 249 Score = 101 bits (243), Expect = 1e-20 Identities = 59/216 (27%), Positives = 106/216 (49%), Gaps = 1/216 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + +T N E Q +K D+ + I D+T+E+D+++++ +T+ H+G + Sbjct: 27 LAQEGASVVITDINAELAQATAKALQDEGLAAHCIVGDITQEADVQRLVDETVAHFGGVH 86 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 +LVNNAG + S +D +MN ++ + +PH +E Sbjct: 87 ILVNNAGAPRDKYLVKMSADDWDFVMNVMLKGAFLAARAVMPHFIEQGWGRLINISSRAH 146 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 P Y+ +KA + + +++E G+ NCV PG + TE+ + + Y Sbjct: 147 LGNPTQANYSAAKAGLIGMAKALSMEEGRYGITANCVAPGFMETEMVQ----ALPTYETI 202 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ER + R G+PD++A +AFLAS+ A I+G Sbjct: 203 KERAVAAQPIKRVGRPDDIADAVAFLASERAGFISG 238 >UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Streptomyces sp. Tu6071 Length = 244 Score = 101 bits (243), Expect = 1e-20 Identities = 68/213 (31%), Positives = 102/213 (47%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA +++TGR+ + ++V K + I A+L ES ++ + + +G++DVLVN Sbjct: 27 GADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAELRGESSARRLAQAAVARFGRIDVLVN 86 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSF 449 NAG+ G E T+ A +D + NVR Y+L P + G Sbjct: 87 NAGVFPFGPTERTTEADFDAVFGLNVRVPYFLVAELAPAMARRGHGAIVNVTTAAAAYGA 146 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 G+ Y SKA++ T+ A E P+GVRVN V PG TE G + A L+R Sbjct: 147 AGLGLYGASKAALVLLTKAWAAEYGPRGVRVNAVGPGPTRTE-----GTAPR--GAALDR 199 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 RPG +E+A I FLAS+ +S + G Sbjct: 200 AALAGPARRPGTAEEIAGAIVFLASEQSSFVHG 232 >UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alteromonadales|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) Length = 246 Score = 101 bits (243), Expect = 1e-20 Identities = 59/185 (31%), Positives = 95/185 (51%), Gaps = 1/185 (0%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 L D++ D+E + +G +D L+ NAGI + I + + A +D+ MN NV+ Sbjct: 52 LVFKGDVSVNKDLEDFFNTCYELWGGIDTLIANAGIAQPENIADVTEASFDKCMNINVKG 111 Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA-YNISKASVDQFTRCVALELAPKG 533 +++ ++ +L +K + G+ + Y +KA+V TR A L P+G Sbjct: 112 VFFTVQKSLGYL--NKAASIIILSSIQAQRGAGIWSVYGATKAAVRSLTRSFAQALGPEG 169 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 +RVN ++PGV T + + G +E+Q A L + LGR P E+A + FLASD A Sbjct: 170 IRVNTLSPGVTDTPILTKFGFAEDQLADILAQVSANTPLGRIASPAEIAKSALFLASDNA 229 Query: 714 SNITG 728 S ITG Sbjct: 230 SFITG 234 >UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 251 Score = 101 bits (243), Expect = 1e-20 Identities = 66/217 (30%), Positives = 112/217 (51%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSI-TADLTKESDIEKIIKKTIDHYGKLD 260 L+ G +++L R+ L +V+ + +I AD+T E + + + + YGK+D Sbjct: 27 LAAEGTRIALVSRDEARLNEVAAELIAAGGDAAIFRADVTSEEQVRQAERAILATYGKVD 86 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXXG 437 +L+NNAG+ + ++ ++ R+M+TNV + + + VP + G Sbjct: 87 ILINNAGVNVRKPVVEFTVEEWHRVMDTNVTAAFLMCRSFVPAMSGRGYGRILNMTSIMS 146 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 S PG +AY+ SK ++ TR +ALELAP+G+ VN ++PG TE+ + + E A Sbjct: 147 HVSLPGRIAYSTSKTALLGMTRTLALELAPQGITVNGISPGPFGTEMNKPLMENPETNAQ 206 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 FL + LGR GK +E+ +L S+ A ITG Sbjct: 207 FL----SSIPLGRWGKVEEIGQLAVYLCSEDAGFITG 239 >UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 266 Score = 101 bits (243), Expect = 1e-20 Identities = 67/217 (30%), Positives = 103/217 (47%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L+ GA L L R+ L +V+ + K +T DL + +E + +D +D Sbjct: 29 LADAGASLILAARDAAKLGEVADEVRAKGRDARIVTFDLADMASVEAAARGLVDEGAPID 88 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTM-LAVPHLLESKGXXXXXXXXXG 437 +LVNN GI E G + +SL ++R + NV +IY L L+ P G Sbjct: 89 ILVNNGGIAEWGPLHGSSLDHWERTFDVNVSAIYLLCRELSKPMAERGWGRIINFASYVA 148 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 P + AY SK +V TR VA +LAP GV N + PG+ LT++ ++ Sbjct: 149 ETGRPNLSAYVASKHAVLGLTRAVAADLAPHGVTCNAIAPGIFLTDMAAPTAGHPQRAKI 208 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F ++ A+GR G P E+ + FLAS+ + +TG Sbjct: 209 F----RDAIAIGRFGDPAEIVGPVQFLASEASRYVTG 241 >UniRef50_A0HJB5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Comamonas testosteroni KF-1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Comamonas testosteroni KF-1 Length = 249 Score = 101 bits (243), Expect = 1e-20 Identities = 60/180 (33%), Positives = 93/180 (51%), Gaps = 1/180 (0%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D++ E ++++ +DHYG++D LV +AGI G +E+ +L ++++++ N+ Sbjct: 58 DVSSEKLTQELVASMLDHYGQIDGLVTSAGISRVGDLESMALQEWEQVLQVNLTGTMLSA 117 Query: 372 MLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 H+ + + G G+ P LAY SK +V Q R +A EL P GVRVN Sbjct: 118 RAVASHMKQRRQGSIVAIASINGMLGNPSNLAYCTSKGAVIQMVRSLAAELGPCGVRVNS 177 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++PG I T + L E+ E H L R GK EV +AFL SD++S ITG Sbjct: 178 ISPGYIHTPMTIM--LDEQPVGQAFE---AMHLLKRAGKSQEVGNAVAFLLSDMSSFITG 232 >UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1; Cenarchaeum symbiosum|Rep: Short-chain alcohol dehydrogenase - Cenarchaeum symbiosum Length = 252 Score = 101 bits (243), Expect = 1e-20 Identities = 69/242 (28%), Positives = 117/242 (48%), Gaps = 3/242 (1%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 M GKV L++ GA++ L GR + L+ + ST SI Sbjct: 1 MRLEGKVAVVTGASSDIGASIVRRLAEEGAKVVLLGRRPDALEAARRVSGHEESTASIPC 60 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368 D+T E + ++ + ++ YG++D+LVN AG I + + ++++ NV + Sbjct: 61 DVTDEGQLAQMADRVVEAYGRIDILVNGAGSIHDPKHFHVMPIMDVKKMIHGNVLGVLLP 120 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGV--LAYNISKASVDQFTRCVALELAPKGVRV 542 T + ++++ G R+ P V AY+ +KA+V FT+ +A+E A + +R Sbjct: 121 TRAVLGKMMDTGGVIINIGSISAERAIPRVHLAAYSSTKAAVVMFTKSIAVEYARRNIRC 180 Query: 543 NCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNI 722 NC+NPG++ + + + L + LE E L R G P ++A + FLASD AS I Sbjct: 181 NCINPGIVDSGM-IKPYLEDPDARRILE---ERQPLKRIGTPADIANAVLFLASDEASWI 236 Query: 723 TG 728 TG Sbjct: 237 TG 238 >UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; n=4; Xanthobacter autotrophicus Py2|Rep: 2-(R)-hydroxypropyl-CoM dehydrogenase - Xanthobacter sp. (strain Py2) Length = 250 Score = 101 bits (243), Expect = 1e-20 Identities = 64/188 (34%), Positives = 95/188 (50%), Gaps = 4/188 (2%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 347 L + AD+ E D+ I T++ +G +DVLVNNAGI E G + T + Q+D++M N Sbjct: 55 LRVRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114 Query: 348 VRSIYYLTMLAVPH-LLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 VR I+ +PH LL+ G + +FPG AY SK +V Q T+ VA++ A Sbjct: 115 VRGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYA 174 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 G+R N V PG+I T + + E L R + G +VA + FLA Sbjct: 175 GSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEI----GTAAQVADAVMFLAG 230 Query: 705 DLASNITG 728 + A+ + G Sbjct: 231 EDATYVNG 238 >UniRef50_Q82KL5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 273 Score = 101 bits (242), Expect = 2e-20 Identities = 68/220 (30%), Positives = 113/220 (51%), Gaps = 9/220 (4%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 G + ++GR E L+++ ++ L+ +D+ + +++ + YG+LD LV N Sbjct: 28 GHHVVISGRRAEPLRRLERE----TGALACPSDVGDPDAADGLVRTALAAYGRLDGLVLN 83 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AGI G + + SL + +M TNV L A+PHLL++KG +R+ Sbjct: 84 AGIGRGGAVGDVSLEDWHDVMRTNVTGPLLLLRAAIPHLLDTKGAVVAVASVSALRNGAS 143 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL--QRRGGLSEEQ------- 608 + Y SKA++ Q R VA++ +GVR N V P + +E+ +R +EE Sbjct: 144 NVPYATSKAALLQLCRSVAVDYGRQGVRANIVCPSWVRSEMADRRMARFAEEADLKDGSV 203 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +A+ E T+ LGRPG+P E+A I++L S AS + G Sbjct: 204 ESAYEEATRFL-PLGRPGEPREIAEAISWLLSPAASYVNG 242 >UniRef50_A7NL33 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Roseiflexus castenholzii DSM 13941|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus castenholzii DSM 13941 Length = 260 Score = 101 bits (242), Expect = 2e-20 Identities = 64/215 (29%), Positives = 102/215 (47%), Gaps = 1/215 (0%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVL 266 ++ G + + N++ L K + + D + L+I D+ + I++T+ HYGK+D + Sbjct: 28 ARAGGSVVIADINLD-LAKATLERDLQGNGLAIQCDVASSESVRAAIEQTLAHYGKIDAI 86 Query: 267 VNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443 NNA I + + TS Q+D LM TN++S+YY T + L S+G G+ Sbjct: 87 HNNAAISRPSAPLHETSEEQWDALMATNLKSVYYTTFYGIDALKASRGCILNTASMVGVL 146 Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFL 623 AY +K ++ T+ +AL+ A G+RVN + P + T L + AA Sbjct: 147 GQERHAAYVATKGAMIALTKAMALDYASYGIRVNAICPAAVWTPLLHEWVQDQPDPAAAR 206 Query: 624 ERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + H LG D VA FL S+ A ITG Sbjct: 207 QFLDGIHVLGYCPDGDVVADAAVFLLSERARFITG 241 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 101 bits (242), Expect = 2e-20 Identities = 64/241 (26%), Positives = 116/241 (48%), Gaps = 2/241 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 ++F GKVV ++ GA++ + + + V + + L + Sbjct: 5 LDFTGKVVLITGGATGIGRATALAFAQQGARVVVGDVDDRAAETVRLIEESGGTALFVRT 64 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368 D+T +D++++++ T+D YG L V NNAGI+ TG + S +DR + +++ ++ Sbjct: 65 DVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPTGPLAEQSEDDFDRTIAVDLKGVFLA 124 Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 + H+ + G G+ + PG+ Y +K V TR A++ A GVRVN Sbjct: 125 LKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAAIDYAAAGVRVN 184 Query: 546 CVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 + PG++ T + + ++ A + ++ R P+E+A T+ FLASDLAS T Sbjct: 185 ALAPGLVDTPMTK----VWQEDAEIWDAVAASNGFHRAAAPEEIAGTVLFLASDLASFTT 240 Query: 726 G 728 G Sbjct: 241 G 241 >UniRef50_A1SC75 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 244 Score = 101 bits (242), Expect = 2e-20 Identities = 63/188 (33%), Positives = 100/188 (53%), Gaps = 4/188 (2%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII---ETGTIENTSLAQYDRLMNTN 347 LS+ AD+T + +E ++ +D +G++D+LVNNAGI E +T + Q+D + N Sbjct: 49 LSLEADVTDPAGVESAVEAILDAFGRVDLLVNNAGITGSAEATVCHDTPVEQWDLVHAVN 108 Query: 348 VRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 VR + T +P +L K G G+ +FPG AY SK + FTR +A++ A Sbjct: 109 VRGPFLCTRAVLPTMLIQKSGHVITVASVAGLVAFPGRCAYTASKGAAIAFTRSLAVDYA 168 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 GVR N + PG++ T + + L + A +E LGR KP+++A + LAS Sbjct: 169 AAGVRANAICPGMVETPM-TQWRLDVPELRAQVE---SKIPLGRVAKPEDIADAVVALAS 224 Query: 705 DLASNITG 728 D + +TG Sbjct: 225 DKLAYMTG 232 >UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Comamonas testosteroni KF-1|Rep: Short-chain dehydrogenase/reductase SDR - Comamonas testosteroni KF-1 Length = 263 Score = 101 bits (242), Expect = 2e-20 Identities = 61/191 (31%), Positives = 99/191 (51%), Gaps = 1/191 (0%) Frame = +3 Query: 159 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRL 335 D + LS+ D+T E+ IE + K D +G+ D+LVNNAG++ +E +A +D++ Sbjct: 54 DNAQAALSLACDITDEAAIEAMAAKVKDTFGRCDILVNNAGVMAPVVPLEELPVAMWDKV 113 Query: 336 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515 M+ N+R + V +LE K G R + Y SKA V T +A+ Sbjct: 114 MSVNLRGSFLCAKYLVRMMLEQKRGAIVNLASIGARVPNDIGPYGPSKAGVLGLTHQMAV 173 Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695 E P+GVR N ++PG+I T + +E+ + R K +GR G+P+++A + F Sbjct: 174 EWGPRGVRTNSISPGMIRTPMSEHFYQNEKLHQG---RIKVV-PVGRIGRPEDIADAMGF 229 Query: 696 LASDLASNITG 728 + SD AS + G Sbjct: 230 IVSDAASYMNG 240 >UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Short chain dehydrogenase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 269 Score = 101 bits (242), Expect = 2e-20 Identities = 65/216 (30%), Positives = 105/216 (48%), Gaps = 5/216 (2%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA++ + GR E Q V + K S D+T + IEK+I T + YGK+D+LVN Sbjct: 32 GAKVVICGRREEKGQAVVDNITKEGGESSYHFFDITNTNSIEKLIDDTAEKYGKIDILVN 91 Query: 273 NAG--IIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGI 440 NA ++ G I+ ++ +D + +++R +Y T +P+L E+ G Sbjct: 92 NAANVALKDGNIDELTIDMWDAIFESDLRGTFYATKCVIPYLQKNENGGSIINIGSMASC 151 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 G AY +K+ VD FT+ AL+ +R NCV PG+I+T + + E F Sbjct: 152 GGDLGSTAYACAKSGVDMFTQYTALQYGKDNIRCNCVRPGLIVTP-ENEANVPEVLRNIF 210 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L + R G P+++ +LASD + +TG Sbjct: 211 LNNI----MVNRYGGPEDIGHMCVYLASDESEYVTG 242 >UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=2; Bacillus|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 252 Score = 101 bits (241), Expect = 2e-20 Identities = 62/211 (29%), Positives = 105/211 (49%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++++ R+ LQ+ + + + L+I AD+T +++ EK+ + ++ YG +D+LVNN Sbjct: 31 GAKVAIVARDAHGLQEAKR---QLGNVLTIQADVTDKNEREKVFSQLLETYGTIDILVNN 87 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG G I T L+ ++ + N S + + LA+P + + R G Sbjct: 88 AGGSNGGLISETELSLFEEAFSLNYFSAVHFSQLALPVMKAKQSGAIINISSIFGRESGG 147 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 YN +KA++ FT+ +A E+ G+RVN + PG IL EE + Sbjct: 148 KATYNSAKAAMISFTKSLADEVIRDGIRVNGIAPGSILHPTGNWQKRLEENREKMEQFID 207 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 + GR G +E+A FLAS+ AS + G Sbjct: 208 QNIPAGRFGTVEEIANVAVFLASEKASWVVG 238 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 101 bits (241), Expect = 2e-20 Identities = 72/241 (29%), Positives = 116/241 (48%), Gaps = 6/241 (2%) Frame = +3 Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSITADLT 200 GKVV L GA+++L N ++L K + + +IT ++T Sbjct: 3 GKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNVT 62 Query: 201 KESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTML 377 E D+E +K+T+D +GK+DV NNAG+ I A ++++M+ NV + +L + Sbjct: 63 VEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGV-FLGLK 121 Query: 378 AVPHLLESKGXXXXXXXXXGIR--SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCV 551 V ++ +G G+++Y SK +V T+ ALE+A G+RVN V Sbjct: 122 HVMKQMKKQGYGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAALEVASDGIRVNAV 181 Query: 552 NPGVILTEL--QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 P I T++ + L+ + E K+ GR G P+EVA + FLASD AS + Sbjct: 182 APAAIDTQMLADIQNNLTPGEPEKSGEALKQGIPAGRFGAPEEVAQVVKFLASDDASFVN 241 Query: 726 G 728 G Sbjct: 242 G 242 >UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 257 Score = 101 bits (241), Expect = 2e-20 Identities = 65/220 (29%), Positives = 114/220 (51%), Gaps = 6/220 (2%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263 ++ GA L L RN+E + + + K ++ D+ ++ +++ ++ T++ +GK+D+ Sbjct: 32 AEAGASLVLCSRNLEQCEDAAANIRKLGVECDALRCDIGEQDEVKAVVAHTMNRFGKIDI 91 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXGI 440 LVNNAGI G +++T L ++D+L +TNVR Y+ T V P + G G+ Sbjct: 92 LVNNAGISWGGELQDTPLKKWDQLYSTNVRGNYFFTTEVVSPMIAGGGGNIINIVSIGGV 151 Query: 441 RSF-PGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 RS P V+ AY +K ++ T+ ++ A +RVN + PG+ TE+ + L Sbjct: 152 RSTDPKVVTFPAYASTKGAIIALTKHLSRNWAKHNIRVNAIAPGIFPTEISKT--LMVGP 209 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A +E LGR G+ D+ FLA+D + +TG Sbjct: 210 QKAVMEAAV---PLGRLGEKDDFKGAALFLAADASRYVTG 246 >UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Herpetosiphon aurantiacus ATCC 23779 Length = 257 Score = 101 bits (241), Expect = 2e-20 Identities = 67/243 (27%), Positives = 118/243 (48%), Gaps = 3/243 (1%) Frame = +3 Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSI 185 T + +GKV ++ GA++ + R +E+LQ V+ ++ T L++ Sbjct: 3 TFDLSGKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAM 62 Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIY 362 K ++ ++ +T+ +G++D++VNNA G + N+ +Q+D+ NV+ + Sbjct: 63 ACHTGKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYF 122 Query: 363 YLTMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 +L A + + G G++ + Y+ISKA+V T+ +A EL P +R Sbjct: 123 WLIQAAAEAMQAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIR 182 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN + PG+I T+ +E+ + T LGR G DEVAA +LASD A+ Sbjct: 183 VNALAPGLIKTKFSSALWDNEDLNQKIVAGT----PLGRIGTVDEVAAAALYLASDAAAF 238 Query: 720 ITG 728 TG Sbjct: 239 TTG 241 >UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 251 Score = 101 bits (241), Expect = 2e-20 Identities = 57/185 (30%), Positives = 99/185 (53%), Gaps = 1/185 (0%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 +++ AD++ ++++ + K D +G LD +VNNAGI+ +G +E +D +M+ N + Sbjct: 59 ITVCADVSSKAEVRAMAKAVGDAFGHLDAVVNNAGILISGDVEGLDEEHWDSVMDVNAKG 118 Query: 357 IYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 533 + + +P + + G G P Y+ SKA+V FTR +A E+ G Sbjct: 119 TFLVVQAVLPMMKARRYGRIVNIASIGGKHGAPEQAHYSASKAAVMGFTRVLAQEVGVDG 178 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 + NCV PG+ILT++ R L + A + ++ A+ R G P++V +AF ASD A Sbjct: 179 ITANCVCPGIILTDM-GRVNLDD---PAVKKSWQDKTAMRRIGDPEDVVGAVAFFASDDA 234 Query: 714 SNITG 728 + +TG Sbjct: 235 AFVTG 239 >UniRef50_A3Q322 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 268 Score = 101 bits (241), Expect = 2e-20 Identities = 65/217 (29%), Positives = 103/217 (47%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L+ GA++++ R+ + ++ L I D+ + + + + +T+ G + + Sbjct: 32 LAAFGARVAIWERDADRCAVAAES----VGGLGIVTDVRESAAVTAALDRTVAELGTVTI 87 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXXG 437 LVNNAG + + TS +D L N+R + T ++ + G G Sbjct: 88 LVNNAGGTFSSPLLETSENAWDALYKANLRHVLLCTQRVAQQMVAAGVGGSVITVTSIEG 147 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 +R+ PG AY +KA V +T+ A ELAP G+RVN + P V++TE GL Sbjct: 148 VRAAPGYAAYAAAKAGVVNYTQTAAFELAPHGIRVNALAPDVVVTE-----GLVALSPGG 202 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + +GRPG DE+A FLASDLA ITG Sbjct: 203 LPAGIGDAIPMGRPGTVDEIAGAAVFLASDLAGYITG 239 >UniRef50_A0JC04 Cluster: (R)-2-octanol dehydrogenase; n=2; Pichia|Rep: (R)-2-octanol dehydrogenase - Pichia finlandica Length = 254 Score = 101 bits (241), Expect = 2e-20 Identities = 63/185 (34%), Positives = 96/185 (51%), Gaps = 3/185 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + AD +KE D +K+I +T+ +G LD++ NAGI + T + +++ N+ ++ Sbjct: 65 VQADSSKEEDNKKLISETLATFGGLDIVCANAGIGKFAPTHETPFDVWKKVIAVNLNGVF 124 Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSF---PGVLAYNISKASVDQFTRCVALELAPKG 533 L LA+ + LE K + SF PG+ Y +K V T+ +ALE A G Sbjct: 125 LLDKLAINYWLE-KSKPGVIVNMGSVHSFVAAPGLAHYGAAKGGVKLLTQTLALEYASHG 183 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 +RVN VNPG I T L +E L++ H +GR G+P+EVA +AFL S A Sbjct: 184 IRVNSVNPGYISTP------LIDEVPKERLDKLVSLHPIGRLGRPEEVADAVAFLCSQEA 237 Query: 714 SNITG 728 + I G Sbjct: 238 TFING 242 >UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein; n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like protein - Streptomyces natalensis Length = 257 Score = 100 bits (240), Expect = 3e-20 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 9/220 (4%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA + L R V+ L+ + + + A I D+++E D+ + ++ T++ YG+LD+ N Sbjct: 34 GAAVVLAARRVDRLRALVSEIRRTGAEAAYIATDVSQEEDVRRAVEFTVEKYGRLDLAFN 93 Query: 273 NAGI-IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXXGIR 443 NAG+ + ++ YD +M TNVR +++ + +L + G G++ Sbjct: 94 NAGVGCDHESMHLMQQDTYDDVMGTNVRGVWHCLQHEISAMLHNGVGGSIVNNSSVAGLQ 153 Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL-----QRRGGLSEEQ 608 + P Y SK +V T+ A E AP+G+RVN V PG TE+ R GL E+ Sbjct: 154 AIPAGAPYIASKHAVIGLTKAAAAEYAPQGIRVNSVAPGTTRTEIIAGWFDRNPGLEEQL 213 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + A + R +P+E+A +A+L SD +S +TG Sbjct: 214 HRATPQ--------ARTAEPEEIAQAVAWLCSDRSSFVTG 245 >UniRef50_Q1JZ17 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Desulfuromonas acetoxidans DSM 684 Length = 252 Score = 100 bits (240), Expect = 3e-20 Identities = 61/188 (32%), Positives = 96/188 (51%), Gaps = 2/188 (1%) Frame = +3 Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GT-IENTSLAQYDRLMNT 344 S + D++ E ++ + YG+LD+LVNNA + + GT +E+ +L ++ L+N Sbjct: 51 SVIGKLVDVSDEKAVQLLFSWLEATYGRLDLLVNNAAVAKAHGTPLESLALEEWQHLLNV 110 Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 N+ + + A P L G ++S P AY SK V T +AL L Sbjct: 111 NLTGPFLCSKYAAPLLRHPSGSIIHIASTRAVQSEPDSEAYAASKGGVVALTHAMALSLG 170 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 P+ +RVNC++PG I ++G Q + + E H +GR G+P ++AAT+ FLAS Sbjct: 171 PQ-IRVNCISPGWIDVSALKKGAHGISQ--SLSRQDHEQHPVGRVGQPQDIAATVCFLAS 227 Query: 705 DLASNITG 728 A ITG Sbjct: 228 AQAGFITG 235 >UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 252 Score = 100 bits (240), Expect = 3e-20 Identities = 61/209 (29%), Positives = 101/209 (48%), Gaps = 1/209 (0%) Frame = +3 Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284 + L G +E+L SK L++ D+++ +D++ + I +GK+D+L NNAGI Sbjct: 35 IDLDGGKLEHL--ASKITSSGGICLALRGDVSQSADVQNALNTAIGRFGKIDILFNNAGI 92 Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVL 461 + G I+ T+ Q+DR M NV+S+Y VPH E G +R+ Sbjct: 93 VPAGKIDVTTEEQWDRAMAINVKSMYLFCHAIVPHFKEHGGGVILNTASATALRAVVDRA 152 Query: 462 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 641 Y +KA+V T+ +AL+ +RVNC+ PG + T + A + Sbjct: 153 CYTATKAAVVGLTKSMALDYVRDNIRVNCLCPGTVDTPSLSERLAAFPDPAEAKKNFIAR 212 Query: 642 HALGRPGKPDEVAATIAFLASDLASNITG 728 +GR G +E+A +L SD ++ +TG Sbjct: 213 QPMGRFGTAEEIALAALYLVSDESAFVTG 241 >UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain type dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 252 Score = 100 bits (240), Expect = 3e-20 Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 6/187 (3%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + D+T E+ + +I + ++ G LD L NAG+ +G I A +D L N R+ + Sbjct: 58 VQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRSGAIAGFEQANWDALFAVNARAHF 117 Query: 363 YLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 + A+PHL S KG G R PG++AY+ SK +V FT +ALELAP +R Sbjct: 118 FGAKHAIPHLQRSGKGSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALALELAPDNIR 177 Query: 540 VNCVNPGVILTELQR-----RGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 VN + PG + T + GG +Q ++ LGR E+A +LAS Sbjct: 178 VNAICPGWVDTAFNQPAIDFMGGADAQQ-----KKIASLVPLGRQASATEIAPLFVYLAS 232 Query: 705 DLASNIT 725 D ++ +T Sbjct: 233 DESAYVT 239 >UniRef50_Q0FWD5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseovarius sp. HTCC2601 Length = 255 Score = 100 bits (240), Expect = 3e-20 Identities = 60/186 (32%), Positives = 96/186 (51%), Gaps = 2/186 (1%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 +++ D++ E ++ + + I +G LD +VN AG+ G I +T +D MN N+ Sbjct: 58 VAVGVDVSDEDKVDAMTAEGIAKFGGLDGVVNCAGVRGVGNILDTDHGVWDLNMNVNIEG 117 Query: 357 IYYLTMLAVPHLLESK--GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530 + + + E G G+ + P L+Y SK V TR VA+E+AP Sbjct: 118 SFNTSQAFCRYAREHNRPGSIVNISSQAGVEAVPNRLSYVTSKHGVVGLTRGVAIEMAPH 177 Query: 531 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 710 G+R N + PG+I T + E LE+ ++ H +GR G+P+E+AA I+FL SD Sbjct: 178 GIRCNGIAPGMIATAMTAGMRADPEN----LEKIRKAHPIGREGQPEEIAAVISFLLSDD 233 Query: 711 ASNITG 728 AS +TG Sbjct: 234 ASYVTG 239 >UniRef50_A5FD58 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase SDR precursor - Flavobacterium johnsoniae UW101 Length = 247 Score = 100 bits (240), Expect = 3e-20 Identities = 69/213 (32%), Positives = 104/213 (48%) Frame = +3 Query: 90 KLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 K GA + +TGRN ENL+K + + + +I +D SD+ + K ++ LDVL Sbjct: 27 KAGANVWITGRNSENLEKAANEINS-QKLKTIVSDTANLSDLSLLEKAFAENNAPLDVLF 85 Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449 NAGI +IE+ + A +D NTNV+ ++ +PHL E S Sbjct: 86 LNAGIARFTSIEDVTEADFDAQFNTNVKGHFFTLQKLLPHLAEGSS-VIFTSSTVATASN 144 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 G Y+ +K ++++ + A ELA + +RVN V+PG + T GL E Sbjct: 145 LGSSIYSATKGALNKIAQIAANELAGRKIRVNIVSPGPVSTP-----GLHNAVPEEAKEY 199 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A+ R G E+A T+ FLAS+ AS ITG Sbjct: 200 LAGATAMQRLGDSSEIAKTVLFLASENASFITG 232 >UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 253 Score = 100 bits (240), Expect = 3e-20 Identities = 62/174 (35%), Positives = 88/174 (50%), Gaps = 5/174 (2%) Frame = +3 Query: 222 IIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES 401 ++ + ++ G +D+L+N AGI+ G E TS + R M+ N+ ++L ++PHL S Sbjct: 69 LVTEAVEVLGGIDILLNVAGIMTWGRFEETSPQAWQRTMDINLSGPFFLIQASIPHLKAS 128 Query: 402 KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 581 KG G+ G AY +SKA V T+ ALE A GVR N V PG + T + Sbjct: 129 KGNVVSVASAGGLHPVYGTSAYGVSKAGVIAITQSAALEFARFGVRANAVAPGGVATPMH 188 Query: 582 RR----GGLSEEQYAAFLERTKETHALGRPG-KPDEVAATIAFLASDLASNITG 728 + GG+ +A R RP P+EVAA IA+LASD A TG Sbjct: 189 EKSSAGGGVDPAIFAEAAGRNM-PKLTDRPACTPEEVAAAIAYLASDEARYATG 241 >UniRef50_Q0UWB9 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 300 Score = 100 bits (240), Expect = 3e-20 Identities = 63/188 (33%), Positives = 106/188 (56%), Gaps = 4/188 (2%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVR 353 L+I AD T ESD+E +KKT+ +G+LD + NAG ++ ++ +T+ ++ +M TN R Sbjct: 106 LTIAADATNESDVEACVKKTVQRFGRLDCALLNAGERDDSKSLFDTTAEDFESIMTTNAR 165 Query: 354 SIYYLTMLAVPHLLESK---GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 S +L + V +L + G G+R FPG+++Y+ SK ++ A EL Sbjct: 166 SA-FLGLKHVAKVLRDQGQGGSIILRSSIAGLRGFPGLISYSSSKFALRGIALTAAEELG 224 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 704 +RVN ++ +I + + G ++E+ L+ K ALGR G+PD+VA +AFLAS Sbjct: 225 EFDIRVNTIHTSIIDSGPGFKEGWTQER----LDELKGETALGRFGRPDDVANVVAFLAS 280 Query: 705 DLASNITG 728 + + +TG Sbjct: 281 EDSKFMTG 288 >UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Short-chain dehydrogenase/reductase SDR - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 253 Score = 100 bits (239), Expect = 4e-20 Identities = 67/214 (31%), Positives = 113/214 (52%), Gaps = 3/214 (1%) Frame = +3 Query: 96 GAQLSLTGRN--VENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 GA + + R+ +E L+ + +K A L+I ADL++E+++E++ + G ++ LV Sbjct: 34 GASVIINYRSSELEALRLARELREKGAGVLAIRADLSRENEVERMFTRIEAEMGNVNALV 93 Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRS 446 NAGI + G + S Q+DR+M+TN++ + A+P+++ + G GI Sbjct: 94 YNAGISQRGLLIECSEEQWDRVMDTNLKGAFLCCRRALPYMIRERFGRIINIASVLGITG 153 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626 Y+ +K + TR +A E+ P G+ VN + PG I T++ R L E++ A + Sbjct: 154 ASYESIYSSAKGGLIALTRSLAQEVGPSGITVNAIAPGPIFTDMLRE-ELDEDEMA---D 209 Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 T+E +GR G P +VAA FL AS I G Sbjct: 210 LTREI-PVGRLGCPKDVAAACVFLLGREASFING 242 >UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentisphaera araneosa HTCC2155|Rep: Glucose-1-dehydrogenase - Lentisphaera araneosa HTCC2155 Length = 264 Score = 100 bits (239), Expect = 4e-20 Identities = 52/189 (27%), Positives = 100/189 (52%), Gaps = 2/189 (1%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 ++ L++ D+ + + +I K I+ +G++D +VNNAGI T+ +D+++NTN Sbjct: 51 SNALAVACDVCSDEAQQNVIDKAIEKWGRVDCIVNNAGINFAKPFLETTKQDWDKVLNTN 110 Query: 348 VRSIYYLTMLAVPHLL--ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 521 +R++++ + + ++KG + PG Y +K + +C EL Sbjct: 111 LRAVFFFMQKLCKYWIDNQTKGSIVNISSVHNQATLPGAGPYAATKNGLLGIMKCAVNEL 170 Query: 522 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701 + KG+RVN V+PG+ T + + + L+ K+ +GRP +P+E+ T++FL Sbjct: 171 SSKGIRVNTVSPGLCNTNIWQDIIEAAPNEKECLDYWKQQIPIGRPSEPEEIGYTVSFLL 230 Query: 702 SDLASNITG 728 SD +S+ TG Sbjct: 231 SDRSSSTTG 239 >UniRef50_A5UQR1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Roseiflexus|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 264 Score = 100 bits (239), Expect = 4e-20 Identities = 62/184 (33%), Positives = 100/184 (54%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 ++I DL++ +D E+++ T++ +G+LD+LVNNAGI + + + + ++D L+NTN+RS Sbjct: 80 IAIPGDLSRVADCERVVDATLEQWGRLDLLVNNAGIWGSTPVGSVTEERWDELLNTNLRS 139 Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 ++++ A L S G R + Y ISK V TR +A +LAP+ + Sbjct: 140 MFFVAQRAADALRASHGVIINIADVGVERPWRNHTPYLISKGGVVTLTRALAKDLAPE-I 198 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 RVN + PG +L L ++ A ER T L R G P+++A + FLA A Sbjct: 199 RVNAIAPGPVL--------LPDDWGAEQAERVARTTLLRRIGSPEDIADAVIFLAQ--AG 248 Query: 717 NITG 728 ITG Sbjct: 249 YITG 252 >UniRef50_A1W5S4 Cluster: Short-chain dehydrogenase/reductase SDR; n=30; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Acidovorax sp. (strain JS42) Length = 257 Score = 100 bits (239), Expect = 4e-20 Identities = 61/216 (28%), Positives = 108/216 (50%), Gaps = 5/216 (2%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 G + + G E ++ K+ ++TA+LTK+ D+ ++K + + +D+LVN Sbjct: 31 GGNVVIVGNRPEKTEEARKELAALGQVSALTANLTKDEDVAALLKAIDEQHPDIDLLVNA 90 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG+ S A YD+ M N ++ +++T V L +KG + + Sbjct: 91 AGVFFPKPFLEHSDADYDQYMKLN-KAFFFITQ-KVAGNLAAKGKPGAIVNIGSMWAKQA 148 Query: 456 VL-----AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 + AY+++KA + T+ +A+ELAPK +RVN V+P V+ T + G + + + Sbjct: 149 IAATPSSAYSMAKAGLHSLTQHLAMELAPKHIRVNAVSPAVVETPIY-EGFIPKAEVHGA 207 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ H +GR G P +VA + FL SD A +TG Sbjct: 208 MQGFNSFHPIGRVGTPQDVAEAVVFLLSDKAGWVTG 243 >UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular organisms|Rep: Glucose 1-dehydrogenase - Bacillus subtilis Length = 261 Score = 100 bits (239), Expect = 4e-20 Identities = 57/184 (30%), Positives = 95/184 (51%), Gaps = 2/184 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + D+TKE D++ I++ I +G LD+++NNAG+ L +D+++ TN+ + Sbjct: 62 VQGDVTKEEDVKNIVQTAIKEFGTLDIMINNAGLENPVPSHEMPLKDWDKVIGTNLTGAF 121 Query: 363 YLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 + A+ + +E+ KG + +P + Y SK + T +ALE APKG+ Sbjct: 122 LGSREAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGI 181 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 RVN + PG I T + +Q A + +G G+P+E+AA A+LAS AS Sbjct: 182 RVNNIGPGAINTPINAEKFADPKQKA----DVESMIPMGYIGEPEEIAAVAAWLASKEAS 237 Query: 717 NITG 728 +TG Sbjct: 238 YVTG 241 >UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 246 Score = 99 bits (238), Expect = 6e-20 Identities = 67/218 (30%), Positives = 110/218 (50%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLT-GRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 257 L++ GA + + N E +KV + + ++I AD+ ++ ++K+TID +G + Sbjct: 24 LARHGANVVVNYAGNKEKAEKVVAEIKELGVEAIAIQADVADSESVQAMVKETIDTFGAV 83 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXX 434 D+LVNNAGI +D +++TN++ +++ + P + + G Sbjct: 84 DILVNNAGITRDNLFMRMKEEDWDAVIDTNLKGVFHCSKAVTRPMMKQRFGRIINVSSVV 143 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G G Y +KA V T+ +A ELA + + VN V PG I T++ G L E+ A Sbjct: 144 GAIGNAGQANYVAAKAGVIGLTKTLARELANRNITVNAVAPGFIETDM--TGELPEDVKA 201 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L + L R G+P+EVA + FLASD AS +TG Sbjct: 202 QMLGQI----PLARLGQPEEVAKAVRFLASDDASYLTG 235 >UniRef50_Q9HT52 Cluster: Probable short-chain dehydrogenase; n=6; Pseudomonas aeruginosa|Rep: Probable short-chain dehydrogenase - Pseudomonas aeruginosa Length = 252 Score = 99 bits (238), Expect = 6e-20 Identities = 58/185 (31%), Positives = 97/185 (52%), Gaps = 5/185 (2%) Frame = +3 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 ADL + ++ K + G+LD LVN AG+ G +EN + +D ++ N+++ +Y+ Sbjct: 55 ADLRSADNCHTLMSKILARTGRLDALVNAAGVWREGPVENFTEEDFDLVLGVNLKASFYM 114 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 A+P+L E++G G +++ G AY SKA++ ++ +ALELA +GVRVN Sbjct: 115 CQAAIPYLKENQGSIVNISSDSGRQAYRGSAAYCASKAALTMLSKTLALELAEQGVRVNA 174 Query: 549 VNPGVILT-----ELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 V+P I T + +R G + + Y L + R +P+EVA + +L A Sbjct: 175 VSPADIATPMLDYQAERYGMGNPDGYKRALLKDYPQGKAARFIRPEEVAELVWYLCGPQA 234 Query: 714 SNITG 728 ITG Sbjct: 235 EAITG 239 >UniRef50_Q89PN1 Cluster: Blr3449 protein; n=2; Bradyrhizobium|Rep: Blr3449 protein - Bradyrhizobium japonicum Length = 256 Score = 99 bits (238), Expect = 6e-20 Identities = 62/213 (29%), Positives = 108/213 (50%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA++ +T + V+++ D + + D+T ++ ++ + G DV+VN Sbjct: 37 GARVVVTDLGQDRADSVAREIRDGGKEAIGCSLDVTDALACGEVARRVDEELGLADVVVN 96 Query: 273 NAGIIETGTIENTSLAQ-YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSF 449 NAGII I++ + + ++ + NV + + +P L +S G S Sbjct: 97 NAGIIIREPIDSPRAHENWRQVFDVNVNGTFNVVHAFIPALRKSPGTIINVASVAAFGSM 156 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 G + Y+ SK +V FT+ +A +LAP G+RVN V PG+I TE+ + + + + R Sbjct: 157 GGTVGYSSSKGAVRLFTQALARDLAPDGIRVNAVAPGIIATEMSESTRGNPARLSGLMAR 216 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 T L R G+P+E+AA + FLAS +AS + G Sbjct: 217 T----PLKRVGQPEEIAAPVIFLASAMASYVNG 245 >UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=14; Clostridia|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Clostridium tetani Length = 249 Score = 99 bits (238), Expect = 6e-20 Identities = 55/183 (30%), Positives = 95/183 (51%), Gaps = 1/183 (0%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 I D++ D + +I+K I +GK+D+L+NNAGI + G + +D ++NTN++ ++ Sbjct: 63 IKCDVSSYEDTKLMIEKIIRDFGKIDILINNAGISKIGLFIDMEEEDWDNIINTNLKGVF 122 Query: 363 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 + +P+++ E G G + Y+ SK VD FT+ +A E+ P +R Sbjct: 123 NCSRNVLPYMIGEKNGVIINISSMWGSVGASCEVIYSASKGGVDSFTKALAKEVGPSNIR 182 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 VN ++PGVI T + E+ + K+ L R G+ +++ + FL SD A Sbjct: 183 VNAISPGVINTSMNEWMSCEEK------DSLKDEIPLCRFGECEDIGKAVVFLCSDNAKY 236 Query: 720 ITG 728 ITG Sbjct: 237 ITG 239 >UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=21; Bacteria|Rep: Short-chain dehydrogenase/reductase - Klebsiella pneumoniae Length = 302 Score = 99 bits (238), Expect = 6e-20 Identities = 61/184 (33%), Positives = 98/184 (53%), Gaps = 1/184 (0%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRS 356 +I D+ E+ ++K+ +D G LD+LVNNAG + +IE+ + ++D TNV + Sbjct: 112 AIPGDIRDETFCNHLVKQAVDALGGLDILVNNAGRQQFCESIEDLTTEEFDATFKTNVYA 171 Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 ++++T A+PH +L Y +KA++ FT+ +A +LAPKG+ Sbjct: 172 MFWITKAAIPHFSRDS-VIINTSSVQAYEPSEILLDYAQTKAAIVAFTKSLAKQLAPKGI 230 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 RVN V PG T LQ GG +E+ +E+ LGRPG+P E+A LA++ S Sbjct: 231 RVNAVAPGPYWTVLQCCGGQPQEK----IEKFGANAPLGRPGQPVEIAPLYVTLAAEENS 286 Query: 717 NITG 728 +G Sbjct: 287 YTSG 290 >UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clostridium kluyveri DSM 555 Length = 250 Score = 99 bits (238), Expect = 6e-20 Identities = 59/219 (26%), Positives = 120/219 (54%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVEN--LQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKL 257 ++K GA++ + N + L+ V + D +++++ AD++K ++++K+I ++++G++ Sbjct: 25 MAKEGARIIVNYNNSKKKALEVVKEIEDIKGTSIAVKADVSKRNEVKKMIDIAVENFGEI 84 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437 +LVNNAGI++ E+ + ++D++ N++ + T +P++L++ G Sbjct: 85 HILVNNAGILQQKPFESITDDEWDKMFQVNMKGAFICTQECIPYMLKNNFGRIINISSIG 144 Query: 438 IRSFPGVLA--YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 + G LA Y+ +KA + R +A + G+ NC+ PG++LTE+ + +E Sbjct: 145 -GQWGGNLAVHYSATKAGIISLARSLARIYSKDGINTNCIAPGLVLTEMSAKEMATE--- 200 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A E+ K + RP P+E+ FLAS+ S ITG Sbjct: 201 -AGKEKLKGI-PINRPAAPEEIGRIAVFLASEDGSYITG 237 >UniRef50_A4XFC0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Novosphingobium aromaticivorans DSM 12444|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 246 Score = 99 bits (238), Expect = 6e-20 Identities = 65/212 (30%), Positives = 109/212 (51%), Gaps = 1/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA++++ +NV L++ + AS I D + K+++ + LDVL N Sbjct: 29 GARVTIGDKNVAGLEETAA---MMASAPVIQPFDAVDNASCRKLVE--VGARNGLDVLCN 83 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFP 452 +G+++ G E+ SL +D +M N S++ L A+PHL+ESKG ++ Sbjct: 84 ISGVLKWGRSEDFSLEDFDLVMRVNTHSVFTLCQAALPHLVESKGNIVNTASAAALQGIA 143 Query: 453 GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERT 632 +AY SK +V T+ +A+E A +GVRVN + PG + T + ++ + E A + R Sbjct: 144 YTVAYVASKHAVAGMTKSLAVEFASRGVRVNAICPGDVKTPMTQQTAVPENVDWALVMR- 202 Query: 633 KETHALGRPGKPDEVAATIAFLASDLASNITG 728 L +P+++A AFLAS+ A ITG Sbjct: 203 NAPKLLDGSCEPEDIAELFAFLASERARKITG 234 >UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 254 Score = 99 bits (238), Expect = 6e-20 Identities = 68/214 (31%), Positives = 111/214 (51%), Gaps = 3/214 (1%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA++ LT R++ +KV++ ++ D+T E+ +++ GKLDVLVN Sbjct: 32 GAKVWLTDRDLAGAEKVAEGIRAAGGQARALLHDVTNEAQWDEVFAAIEAEDGKLDVLVN 91 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRS 446 NAGI I + A ++ + N+ S++ T AV + ++ KG G+ Sbjct: 92 NAGIAVLRPIAEMTTADWNLQNSVNLDSVFQGTKRAVVLMRKTGTKGSIINISSVAGLIG 151 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 626 P AY +K V F++ +A+E A G+RVN V+PG+ILT +Q G+++E AA + Sbjct: 152 VPACGAYAAAKGGVRLFSKTIAVETAKDGIRVNSVHPGMILTNIQ---GVAQEDNAANYD 208 Query: 627 RTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 T +G G P ++A FLASD + +TG Sbjct: 209 ATLALVPMGYMGDPLDIANMNLFLASDESRYVTG 242 >UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Trichocomaceae|Rep: 3-ketoacyl-acyl carrier protein reductase - Aspergillus fumigatus (Sartorya fumigata) Length = 256 Score = 99 bits (238), Expect = 6e-20 Identities = 72/249 (28%), Positives = 114/249 (45%), Gaps = 10/249 (4%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS------ 173 M+ GK+ L+K GA L+L + + Q +++ CD+ S Sbjct: 1 MSLRGKIAIVTGASRGIGAGIALDLAKQGANLTLIYTSASSDQAINQLCDQIHSLNNGST 60 Query: 174 TLSITADLTKESDIEKIIKKTIDHY----GKLDVLVNNAGIIETGTIENTSLAQYDRLMN 341 + + ADL +I+ T D + K+D+LVNNAG+ + +T+ + + Sbjct: 61 AIKVQADLRHSDAPAQILAATFDAFPNANNKIDILVNNAGVSLCKNLADTTDHDISSVFD 120 Query: 342 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 521 NV + +T +PHL + G R PG Y+ SKA+V+ FTR +A EL Sbjct: 121 INVYGLISMTRAVIPHL-RAPGRIINLSSVAARRGSPGFSVYSASKAAVEGFTRSLACEL 179 Query: 522 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701 P G VN V PG + +++ RR + E+ A E T H R P++ A + FLA Sbjct: 180 GPVGCTVNAVQPGAVESDMLRR-EVPEQLIAYIQENTPLGH---RIALPEDTARVVTFLA 235 Query: 702 SDLASNITG 728 + A +TG Sbjct: 236 GEGAGWVTG 244 >UniRef50_A1DIX9 Cluster: 1,3,6,8-tetrahydroxynaphthalene reductase; n=5; Pezizomycotina|Rep: 1,3,6,8-tetrahydroxynaphthalene reductase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 276 Score = 99 bits (238), Expect = 6e-20 Identities = 62/224 (27%), Positives = 115/224 (51%), Gaps = 9/224 (4%) Frame = +3 Query: 84 LSKLGAQLSLT-GRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKL 257 L++ GA +++ G + ++ Q+V + S ++I ADLT +IE +IK+ + H+G+L Sbjct: 32 LARRGASVAINYGHSAKSAQEVVEAIQAIGSQAVAIKADLTCVPNIESLIKQVVSHFGRL 91 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437 D++V+N+G+ + +E T+L ++ + N N R+ ++ A H+ G Sbjct: 92 DIVVSNSGMEKFKPLEETTLEDFNEVFNLNTRAQMFVARYAYDHIQPGGRVILMSSIAAG 151 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE---Q 608 + PG Y SKA+++ FTRC+A + KG VN + P + +++ R Sbjct: 152 L-GVPGHALYAGSKAAIEGFTRCLAADFGRKGCTVNAIAPAGVKSDMWRENAWRYAPGCD 210 Query: 609 YAAFLERTKETHALGRP----GKPDEVAATIAFLASDLASNITG 728 ++ LE + A G P G P+++ ++FLAS A + G Sbjct: 211 KSSSLEEIEAALAGGSPLKRCGVPEDIGKVVSFLASPDAEWVNG 254 >UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=26; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 248 Score = 99 bits (238), Expect = 6e-20 Identities = 62/212 (29%), Positives = 108/212 (50%), Gaps = 2/212 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSIT-ADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA + + G N E Q V + +S D++ ++ ++K +D + K+D+LVN Sbjct: 31 GADVEIWGLNEERGQAVIESLTGLGGEVSFARVDVSHNGGVKDCVQKFLDKHNKIDILVN 90 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSF 449 NAGI + S + +++TN+ S+YY + H+++++ G Sbjct: 91 NAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSSVIRHMIKARSGSIINVASIVAKIGS 150 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 G Y +KA + FT+ +A E+A + +RVNC+ PG I T++ L++ A +L Sbjct: 151 AGQTNYAAAKAGIIAFTKSLAKEVAARNIRVNCLAPGFIETDM--TSVLNDNLKAEWL-- 206 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNIT 725 ++ LGR G P++VA FLAS L+S +T Sbjct: 207 --KSIPLGRAGTPEDVARVALFLASQLSSYMT 236 >UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl-CoA reductase; n=2; Alphaproteobacteria|Rep: Short chain dehydrogenase or 3-ketoacyl-CoA reductase - Rhizobium loti (Mesorhizobium loti) Length = 248 Score = 99.5 bits (237), Expect = 7e-20 Identities = 62/184 (33%), Positives = 92/184 (50%), Gaps = 1/184 (0%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359 ++ D+ + +++EK+ + +GK +L+NNA GT E S A Y RL +TNV Sbjct: 60 AVQGDVAEAAEVEKMFEAAEIAFGKPSILINNAATASFGTFEEASEADYRRLFDTNVLGT 119 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 T A+ H E+ G P Y+ SKA++D T ++ EL + +R Sbjct: 120 ILTTKAAMRHFPETGGSIVNIGTISSWNPVPNTSLYSASKAAIDTLTLSLSRELGARNIR 179 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALG-RPGKPDEVAATIAFLASDLAS 716 VN V PG TE+ G+ + L LG R GKPD++A T+AFLASD A+ Sbjct: 180 VNIVAPGYTHTEMTE--GMVGTDFGNMLIAGV---PLGQRFGKPDDIAPTVAFLASDEAA 234 Query: 717 NITG 728 +TG Sbjct: 235 WLTG 238 >UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1; Mesorhizobium loti|Rep: Probable short-chain dehydrogenase - Rhizobium loti (Mesorhizobium loti) Length = 261 Score = 99.5 bits (237), Expect = 7e-20 Identities = 62/192 (32%), Positives = 92/192 (47%), Gaps = 5/192 (2%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 A L T D++ + + + +G +DV+VN+A + GT T ++R M+ N Sbjct: 54 ADALVQTVDVSISDQVRDAVVAGVAKFGGIDVIVNSAAVHPYGTATTTDWETWNRAMSVN 113 Query: 348 VRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 V SIY +P +++ G G V AY +K ++ TR +AL+ A Sbjct: 114 VGSIYLTAHFGIPEMIKRGGGAIVNVASVQGFACQQNVAAYATTKGAIHTLTRSLALDYA 173 Query: 525 PKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE----RTKETHALGRPGKPDEVAATIA 692 G+RVN V+PG I T + + + A +E R H LGR G+P+EVA IA Sbjct: 174 AAGIRVNSVSPGSIRTPILEKAARGDHGSDADVEEAYKRFGAAHPLGRIGEPEEVAEFIA 233 Query: 693 FLASDLASNITG 728 FL S AS TG Sbjct: 234 FLCSSKASFCTG 245 >UniRef50_Q47PV9 Cluster: Short chain dehydrogenase; n=1; Thermobifida fusca YX|Rep: Short chain dehydrogenase - Thermobifida fusca (strain YX) Length = 262 Score = 99.5 bits (237), Expect = 7e-20 Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 6/189 (3%) Frame = +3 Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-----TGTIENTSLAQYDRLMNT 344 ++ DL + + +++++ + G LD LVNNAG+++ T T+E +DR+ Sbjct: 58 AVAVDLADSAQVRRMVEEAVAAGGGLDTLVNNAGVLDSAFTDTPTVEELPEEAWDRVYAV 117 Query: 345 NVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL 521 NV++++ T A PHL S +G + G AY SK +V Q TR +A+ L Sbjct: 118 NVKAVWLATKFAAPHLRASERGPSVVNAASVAGMTGYGSPAYASSKGAVIQLTRSMAIAL 177 Query: 522 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 701 +P+ VR N PG I T + R + E A L H + R G+P EVA + FLA Sbjct: 178 SPQ-VRCNAYCPGSIETPMSRAHLEASEDREARLRSMIGAHLIPRFGRPSEVAKVVCFLA 236 Query: 702 SDLASNITG 728 SD AS +TG Sbjct: 237 SDDASFVTG 245 >UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 249 Score = 99.5 bits (237), Expect = 7e-20 Identities = 65/217 (29%), Positives = 110/217 (50%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 +++ GA++ + RN E +K + +K SI D+ K +DI+K++ + YG++D Sbjct: 26 IAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDVGKVADIKKLVSEVYGRYGRID 85 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437 +LVN AG+ IE + ++ +++ N++ ++ + A H++ K G Sbjct: 86 ILVNCAGVNVRKPIEEYTEEDWNYMVDINLKGTFFACIEAGKHMIAQKEGVIVNLASIQA 145 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 P Y +K V Q T+ +A+E A +RVN V+P I TE+ + + ++ Y Sbjct: 146 EEVLPERGIYATTKGGVKQLTKALAVEWAKYNIRVNAVSPAFIKTEMVEK--VLQDPYWG 203 Query: 618 FLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L K + RPG P+EVA I FL S AS ITG Sbjct: 204 NLIINKT--PMRRPGTPEEVAEAILFLVSPKASYITG 238 >UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain dehydrogenase; n=1; Saccharopolyspora spinosa|Rep: Putative oxidoreductase, short chain dehydrogenase - Saccharopolyspora spinosa Length = 240 Score = 99.5 bits (237), Expect = 7e-20 Identities = 60/183 (32%), Positives = 88/183 (48%), Gaps = 1/183 (0%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 I D+ + ++ + + G LD +VN AGI +G +E +D + NV+S + Sbjct: 47 IKCDVADSGSVAAMVDEAVTGLGGLDAVVNVAGIQRSGAVEVLDETDWDDQLRVNVKSCF 106 Query: 363 YLTMLAVPHLLESKGXXXXXXXXX-GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 + AVPHL + G G++ F G+ AY+ SK +V FTR +A+E+A +R Sbjct: 107 LTSKYAVPHLRAAGGGSITTTASLAGLKGFAGMTAYSASKGAVIAFTRTLAVEVAADNIR 166 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 NC+ PG + T E A L K L R P E+A AFL SD AS Sbjct: 167 ANCLCPGWVDTPFNDPVITFEGGREAHLANVKANVPLSREAAPPELAKWHAFLVSDAASY 226 Query: 720 ITG 728 +TG Sbjct: 227 MTG 229 >UniRef50_Q0RL77 Cluster: Putative Short chain dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative Short chain dehydrogenase - Frankia alni (strain ACN14a) Length = 263 Score = 99.5 bits (237), Expect = 7e-20 Identities = 67/218 (30%), Positives = 103/218 (47%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTIDHYGKLD 260 L GA++++ R L V+ D A+ ++I+ADLT E D+ ++ + +D G +D Sbjct: 30 LDAAGARVAVVARGGAGLAAVA---DGLANKPVTISADLTVEDDVRRVADQALDELGDVD 86 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 +LVNNAG+ E + D +N N+R++ LT P LL +G Sbjct: 87 ILVNNAGLGWHQPPEAITAKPLDLQLNLNLRNVILLTSWLAPSLLRRRGCVVTMSSAAAY 146 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR--GGLSEEQYA 614 Y +K ++ T+ +A +GVRVN V PG + T++ + L EE Y Sbjct: 147 GGDVEQAVYAATKGGLNTLTQNLATAWGDRGVRVNAVAPGFVDTDIWQPLIAALGEEGYQ 206 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F T L R DE+A + FL SD AS +TG Sbjct: 207 RFRRATAAGIPLRRWASADEIATVVLFLCSDAASYLTG 244 >UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobacter sp. NAP1|Rep: Glucose dehydrogenase - Erythrobacter sp. NAP1 Length = 255 Score = 99.5 bits (237), Expect = 7e-20 Identities = 64/210 (30%), Positives = 95/210 (45%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ +TGR + + + A AD T SD++ + D +G++D+L N Sbjct: 36 GAEVIITGRKQKGIDAALAELG--AGAHGFVADSTSISDLQALADFAKDTFGEVDILFAN 93 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG I+ Y R + NV+ ++ +P +L + PG Sbjct: 94 AGNGMFAPIDQVDEELYARQFDLNVKGAFFTVQAFLP-VLSGNSSVIITSSAVHAKGAPG 152 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 Y SKA+V F R +A EL +GVRVN ++PG++ T E Y F Sbjct: 153 GTLYFASKAAVRSFARTMAAELGGRGVRVNTLSPGIVPTNFFENSNAPTELYHDFEAMAG 212 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNIT 725 + LGR GKP E+A FLASD AS +T Sbjct: 213 QGAPLGRAGKPVEIAEVAVFLASDEASFVT 242 >UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 236 Score = 99.5 bits (237), Expect = 7e-20 Identities = 60/184 (32%), Positives = 92/184 (50%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 L++ AD+T E D+ K+ + YG++D LV AG++E + + LA +++ + N+ Sbjct: 47 LTVPADVTSEHDVAKLTSAAVIEYGRIDALVTLAGVMEQTLLPDLDLATWNQTIAVNLTG 106 Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 + A L+++ G G AY SKA V TR +A EL P V Sbjct: 107 TFLCAKAAADELMKTGGTIVTIGSQIGYVGGINCAAYTASKAGVAGLTRALARELGPT-V 165 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 RVNCV PG I T + E ++E+ + +GR G PDEVA +++L D AS Sbjct: 166 RVNCVAPGPIETPMTAVHATPE-----WVEQKTRSLVMGRFGTPDEVATAVSWLVGDEAS 220 Query: 717 NITG 728 +TG Sbjct: 221 FVTG 224 >UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Short-chain dehydrogenase/reductase SDR - Halorubrum lacusprofundi ATCC 49239 Length = 263 Score = 99.5 bits (237), Expect = 7e-20 Identities = 67/219 (30%), Positives = 107/219 (48%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 260 ++ GA + + R ++ V+ + F ITAD+T + D+E ++++ +D +G LD Sbjct: 38 MAAAGATVVPSARTAAEVEAVADEARDFGVEARGITADVTDDDDVEALVEEIVDAFGSLD 97 Query: 261 VLVNNAGIIETGTIENTSLAQ---YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXX 431 +LVNNAG + + + + D +++ N+R + A PHL E+ G Sbjct: 98 ILVNNAGFNPGDALGDPAEIESDAVDSVLDVNLRGAFRTLRAAGPHLKEAGGSVVNVASV 157 Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 G P Y SK + T+ A++ AP+ VRVN V PG + T+L +E Sbjct: 158 AGEVGLPKQHPYVASKHGLVGLTKSAAMDWAPE-VRVNAVAPGYVATDLTETLQENERLR 216 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + L+RT L R P E+A FLASD AS +TG Sbjct: 217 QSILDRT----PLDRFADPMEIAGPAVFLASDAASFVTG 251 >UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex aeolicus Length = 248 Score = 99.5 bits (237), Expect = 7e-20 Identities = 67/218 (30%), Positives = 112/218 (51%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKFA-STLSITADLTKESDIEKIIKKTIDHYGKL 257 L+ G+ + +TG + E + V+++ +K+ + +L E I K ++ + + Sbjct: 27 LASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMNLLSEESINKAFEEIYNLVDGI 86 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434 D+LVNNAGI SL ++ ++ N+ + +T ++ +++ + G Sbjct: 87 DILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIKQRWGRIVNISSVV 146 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 G G + Y+ +KA + FT+ +A ELAP+ V VN V PG I T++ LSEE Sbjct: 147 GFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAPGFIETDM--TAVLSEE--- 201 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ KE LGR G P+EVA + FL S+LAS ITG Sbjct: 202 -IKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITG 238 >UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nitrosospira multiformis ATCC 25196|Rep: Short-chain dehydrogenase/reductase SDR - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 247 Score = 99.1 bits (236), Expect = 1e-19 Identities = 56/187 (29%), Positives = 100/187 (53%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 A ++I AD++ +++ ++ I+ + +LD+LVNNAG++ + + + S ++DR+++ N Sbjct: 57 AEAIAIKADVSNSAEVCRLFDAAIERFQRLDILVNNAGVLLSRKMSDISDDEFDRVLDVN 116 Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527 V+ ++Y A LE G P AY SK +V+Q TR A E+ Sbjct: 117 VKGVFYALREAAVR-LEDGGRVVNLSSTVTRLMLPNYGAYAASKGAVEQLTRVFAREVGD 175 Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 +G+ N V+PG + +E+ G SEE + R LGR G+P+++A + FL S+ Sbjct: 176 RGITANIVSPGPVNSEM-FTAGKSEET----IRRMAAISFLGRVGEPEDIAGVVLFLVSE 230 Query: 708 LASNITG 728 + +TG Sbjct: 231 ESRWVTG 237 >UniRef50_Q3WCZ4 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 524 Score = 99.1 bits (236), Expect = 1e-19 Identities = 56/193 (29%), Positives = 100/193 (51%), Gaps = 7/193 (3%) Frame = +3 Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 350 S D+++ + +++ + +G++DV+ NNAGII + + S Q DR++ N+ Sbjct: 320 SAAPAAVDVSRRDQVVDLVRSAVSDHGRVDVMCNNAGIIIDVPVLDLSEEQLDRVLAVNL 379 Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG-VLAYNISKASVDQFTRCVALELAP 527 + + + A + + + P ++AY+ISKA V Q TR +A EL P Sbjct: 380 KGVLFGCQAAGAVMRSQRAGSIINMASGAFDTAPARLVAYSISKAGVVQITRTLAKELGP 439 Query: 528 KGVRVNCVNPGVILTELQRR------GGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 689 GVRVN + PG++ T++ RR G + E++ FL R+++ L R G +++ Sbjct: 440 DGVRVNAIAPGLVETDITRRHYAAEDGTVDEDKRERFLGRSRDLAPLRRIGTTEDIGHAA 499 Query: 690 AFLASDLASNITG 728 +LAS+ A +TG Sbjct: 500 LYLASEAARFVTG 512 >UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Chromohalobacter salexigens DSM 3043|Rep: Short-chain dehydrogenase/reductase SDR - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 255 Score = 99.1 bits (236), Expect = 1e-19 Identities = 55/182 (30%), Positives = 91/182 (50%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 A+ S ++ +++ +++ + G LD+LVN AG+ E E + +D N Sbjct: 57 ATVESAVGEIGTQAECRAVVETAVARLGGLDILVNCAGVFEEVPFEAVTQEHWDSTFRVN 116 Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527 V ++ A+PHL S G G+ FP Y+ +KA+V TR +ALELA Sbjct: 117 VGGTFFCLQAALPHLEASGGNVVNLGSDAGLIGFPPSSVYSGAKAAVVNLTRALALELAG 176 Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 + +R+NCV PG + T++ + + + A+L+ L R GKP E+A + +LAS Sbjct: 177 R-IRINCVCPGNVETDMIQHAAEASGEPHAYLDAAHRRAPLQRMGKPQEIADAVLYLASP 235 Query: 708 LA 713 A Sbjct: 236 QA 237 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 99.1 bits (236), Expect = 1e-19 Identities = 61/180 (33%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D++ E +I ++ + YG+LDV+ NAG++ T +E+ S +++ + N+ + + LT Sbjct: 63 DVSGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLT 122 Query: 372 MLAVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 A P + +G G +R G +AYN SK + TR +A ELAP +RVNC Sbjct: 123 KYAAPVMRRHEGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLADELAPHNIRVNC 182 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 V PG + T R E A E L R P+EVA + FLA + AS ITG Sbjct: 183 VCPGWVDTPFNR--PFWEHAGAGAEEEVLRGVPLRRQCTPEEVAPAVVFLAGEGASYITG 240 >UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Acyl carrier protein) reductase); n=4; Proteobacteria|Rep: Glucose-1-dehydrogenase, (3-oxoacyl-(Acyl carrier protein) reductase) - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 258 Score = 99.1 bits (236), Expect = 1e-19 Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 4/219 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA-DLTKESDIEKIIKKTIDHYGKLD 260 L K GA + + GR+ LQ+V+ + D + A D+ + + ++ +G +D Sbjct: 26 LVKAGANVVIGGRDAAKLQRVATEIDPSGDHVRFHAGDIAQPATATALVDLAKQAFGGVD 85 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXG 437 +L+NNAG+ A+YD ++T ++ +++ A + L G Sbjct: 86 ILINNAGVFRPKAFLEVEEAEYDWFLDTILKGKFFMAQAAAKAMKLRGGGAIVQTGSLWA 145 Query: 438 IRSFPGV--LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQY 611 +++ AY+ + A V TR +A+ELA +R+N V PGV+ T + ++++Q Sbjct: 146 LQAIGATPSAAYSAANAGVHALTRNLAIELAASNIRINTVAPGVVETPVYNTF-MTDDQV 204 Query: 612 AAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A L H LGR G+P +VA I FLAS AS ITG Sbjct: 205 KATLPAFNAFHPLGRNGQPADVAEAILFLASANASWITG 243 >UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short-chain dehydrogenase/reductase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 99.1 bits (236), Expect = 1e-19 Identities = 73/216 (33%), Positives = 107/216 (49%), Gaps = 10/216 (4%) Frame = +3 Query: 90 KLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 K GA + LTGR+ E Q ++ A I AD++KE DI I +T++ +GKLDVL Sbjct: 29 KEGATVVLTGRSEEKGQAIANRLGDKAHY--IKADVSKEEDIANTISETVERFGKLDVLF 86 Query: 270 NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXGIRS 446 NNAG GTI++ + + ++ + S+ A+ P G IR Sbjct: 87 NNAGGPVGGTIDSIAPGDINYGVDLLLSSVVLGIRYAIEPMKANGGGVIINNTSIAAIRY 146 Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL-----SEEQY 611 G L Y+ KA+V +T+ +EL P G+RVNC++PG I T + G ++E Sbjct: 147 RQGNLLYSALKAAVTHYTKLAGVELGPLGIRVNCISPGAIATPIFWGGSAIANTKTDEDN 206 Query: 612 AAFLERTKETHA----LGRPGKPDEVAATIAFLASD 707 A LE+ K A L PG +++A FLASD Sbjct: 207 ARKLEKLKANLAKATPLQIPGLAEDIANGALFLASD 242 >UniRef50_Q39NI4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia sp. 383|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 261 Score = 98.7 bits (235), Expect = 1e-19 Identities = 64/216 (29%), Positives = 102/216 (47%), Gaps = 1/216 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L++ GAQ+ + +N V + L + D+ + + + + ++ H+G+LD Sbjct: 29 LAQCGAQVVVAEKNAARADAVRERLGG-RDALFVETDVAEPASVAALFERVDAHHGRLDG 87 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI- 440 LVNNAGI G + SL DRL TN+RS++ LA P + + G Sbjct: 88 LVNNAGITLHGPFDAFSLDDCDRLYRTNLRSMFQCAQLAAPRIARAGGGAIVNIASNHAG 147 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 S PG Y +K + +R +A LAP+ +RVN ++PG L G + E+ A Sbjct: 148 ASVPGFEMYAATKGGIVAMSRAMATSLAPQRIRVNTLSPGF---TLNAPIGAALERDPAL 204 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L+ + H R +P ++ AFL SD A+ I G Sbjct: 205 LDAYRALHPAQRINEPADIGRIAAFLLSDAAAGIAG 240 >UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family - Psychroflexus torquis ATCC 700755 Length = 245 Score = 98.7 bits (235), Expect = 1e-19 Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 8/223 (3%) Frame = +3 Query: 84 LSKLGAQLSLTGRN-----VENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHY 248 L + GA+L +T R +++L++ D F S D+T +S +KII T+D + Sbjct: 30 LGEAGAKLVVTSRTDKFGGLDSLKEAGHDVSFFES------DITDKSVPQKIIDYTLDKH 83 Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL-TMLAVPHLLESKGXXXXXX 425 G +D+LVNNAG+ + G +E + D++MN NV S++ + + P + G Sbjct: 84 GVIDILVNNAGVAQHGEMEEFNDELLDKIMNINVDSVFRMCRSVLTPMKKQGSGVILNIG 143 Query: 426 XXXG-IRSFP-GVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLS 599 G + + P +AYN SKA+V T+ +A + A + +RVN + PG TE+ + + Sbjct: 144 SISGLVSNIPQPQVAYNASKAAVHMMTKSLASDFADQNIRVNAIAPGYFRTEMTKLSKET 203 Query: 600 EEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 E Y + + T L R + +E+ A FL S +S +TG Sbjct: 204 EHWYPTWDKMT----PLNRMAETEEIGAAALFLCSPASSYVTG 242 >UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 291 Score = 98.7 bits (235), Expect = 1e-19 Identities = 66/189 (34%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Frame = +3 Query: 174 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT-IENTSLAQYDRLMNTNV 350 ++SI D+ ES ++ +T++H+G+ DVL+NNA + T IE +A +DR + N+ Sbjct: 69 SVSIECDVADESSVKNAAGRTVEHFGRCDVLINNAATLAPATSIEKLLVADWDRTLAINL 128 Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLA-YNISKASVDQFTRCVALELAP 527 R ++ LT + L+ ++G + P Y SKA+V FTR A+E P Sbjct: 129 RGVF-LTTKYLGALMLNQGSGSIVNIASIAATAPNASPQYGASKAAVLAFTRHTAVEWGP 187 Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYA--AFLERTKETHALGRPGKPDEVAATIAFLA 701 +G+R N V+PG I T LSE YA L R R G P ++A +AFLA Sbjct: 188 RGIRANAVSPGFIRTP------LSESNYAEPEMLARRSNMVPSRRLGLPGDIAEAVAFLA 241 Query: 702 SDLASNITG 728 D AS I G Sbjct: 242 GDGASFING 250 >UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|Rep: Glucose 1-dehydrogenase - Synechococcus sp. (strain CC9311) Length = 265 Score = 98.7 bits (235), Expect = 1e-19 Identities = 62/219 (28%), Positives = 112/219 (51%), Gaps = 5/219 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRN-VENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKL 257 + LGA++ + R+ E +++ ++ + ++ + AD++K D++ +I + +GK+ Sbjct: 35 VGSLGAKVVIDYRSHPERTEELIEEVGELGGQSIGVQADVSKLVDLQHLIDTAVQTFGKI 94 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437 DV+VNNAGI +I +TS +D++MN N+R +++ T A ++ S+G Sbjct: 95 DVMVNNAGIETRTSILDTSPDDFDKVMNVNLRGVFFATQYAAKQMI-SQGSGGRIINISS 153 Query: 438 IRS---FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 + P Y ++K V TR +ELA KGV + V PG + T + S Sbjct: 154 VHEDWPMPNNTPYCVAKGGVRMLTRTAGVELAGKGVSIVNVGPGAVATPIND----STMN 209 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNIT 725 L + +GR +P E+A+ +AFLA + AS +T Sbjct: 210 DPELLAKLNAAIPIGRMAQPAEIASVVAFLAGNGASYMT 248 >UniRef50_A5NTZ6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Rhizobiales|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium sp. 4-46 Length = 252 Score = 98.7 bits (235), Expect = 1e-19 Identities = 70/241 (29%), Positives = 119/241 (49%), Gaps = 4/241 (1%) Frame = +3 Query: 18 FAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKD-CDKFASTLSITAD 194 FAG+ V L++ GA+ L GR +E L+ V+ + + S L + D Sbjct: 5 FAGQTVVVTGAGTGMGRAAAIRLAREGARSVLVGRRLEPLEAVAAEIAAEGGSALPVACD 64 Query: 195 LTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLT 371 + +++E ++++ G++D L NAG++ + T ++ L+ TN+ + Sbjct: 65 IGNPAEVEAMVRQATRANGRIDGLFANAGVLGAFKPLAETDATDFEELVGTNLLGTFLSI 124 Query: 372 MLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 ++PHL +G + S PG AY +K ++ +ALE P+ VRVN Sbjct: 125 KHSLPHL---RGGAVVINASWTVNSVMPGAGAYAATKGALIAMMHTLALEQGPRDVRVNS 181 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHA-LGRPGKPDEVAATIAFLASDLASNIT 725 ++PG+ILT + + + ++A L HA LGR G PD+VA T+A+L SD A +T Sbjct: 182 ISPGIILTPM--ADAVLDPAFSAKL----AAHAPLGRNGTPDDVAGTVAWLLSDDARFVT 235 Query: 726 G 728 G Sbjct: 236 G 236 >UniRef50_A4T6Z1 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 291 Score = 98.7 bits (235), Expect = 1e-19 Identities = 67/224 (29%), Positives = 113/224 (50%), Gaps = 9/224 (4%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257 L+ GA ++L GR E L++ + + + +T + AD++K I + + + D G+L Sbjct: 56 LAGSGADIALVGRTREPLERRAAEIAQRWGVNTYPVQADMSKWDQIHRGVAEAHDKLGRL 115 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL-ESKGXXXXXXXXX 434 D+++NN ++ G E + Q D + ++ + Y A+ +LL + G Sbjct: 116 DIMINNPVMVAAGPFEKQTKEQIDLTVLGSLTMMMYGAHAALEYLLPQGSGVIINIGSVG 175 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR---GGLSEE 605 G G+ YN K+ V FTR +A E+AP+GV V CV PG+++ E ++ ++ Sbjct: 176 GRVQQRGLTVYNACKSGVIGFTRNLAHEVAPRGVNVFCVAPGIMIKEQMKQYLFDPQDDQ 235 Query: 606 QYA---AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 Q A A +E LGR P+E A +AFLAS+ AS + G Sbjct: 236 QRAGRGAIIESITHQVQLGRASLPEEAANMVAFLASEAASYMCG 279 >UniRef50_A0VT49 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL 12 Length = 256 Score = 98.7 bits (235), Expect = 1e-19 Identities = 70/216 (32%), Positives = 116/216 (53%), Gaps = 5/216 (2%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++++ N E + V+ + A +++T D++K +D+ + +++TID +G++D+ +NN Sbjct: 36 GARVAIVDLNGEGAKAVADALQQNA--IAVTCDVSKGADVSRAVQETIDAFGRVDIAINN 93 Query: 276 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXXGIRSF 449 AG + + R+ NV SI++ T VPH + G GIR Sbjct: 94 AGWSHRNQPALDVDFETFKRVYEVNVDSIFHATHALVPHWRDIGGGVMINVGSTAGIRPR 153 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE-LQRRGGLSE--EQYAAF 620 PG+ YN SK +V+ T+ +A+ELAP VRV + P + T L+ G+ + E A F Sbjct: 154 PGLSWYNSSKGAVNMMTKTLAVELAPDRVRVCGLAPVMGATPLLETFMGMPDTPENRAKF 213 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 L T LGR +P+++A +LASD A+ ITG Sbjct: 214 L----GTIPLGRLCEPEDMANAALYLASDEANFITG 245 >UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Mycobacterium smegmatis str. MC2 155|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 254 Score = 98.7 bits (235), Expect = 1e-19 Identities = 64/240 (26%), Positives = 111/240 (46%), Gaps = 2/240 (0%) Frame = +3 Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITA 191 N GKV L GA +++ R L+ D L+ + Sbjct: 7 NLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACST 66 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D+T E+ +E+++ T++ +G++D+LVNN+GI+ T + S ++DR++ TN+R + T Sbjct: 67 DITDEASVERLVDATVETFGRVDILVNNSGIVATTPLIEQSADEWDRVVATNLRGTFLAT 126 Query: 372 MLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 HL+ + G ++ AY+ SKA V FTR +A+E A ++VN Sbjct: 127 RAVGRHLVAQRSGKVINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVNA 186 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + PG T L ++ AA + R R G+P+E+ + + LA + +TG Sbjct: 187 IAPGYFATSL-NADMRADADMAAKVVRAIPAR---RMGEPEELTSWLLLLAGSASDFMTG 242 >UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella woodyi ATCC 51908 Length = 251 Score = 98.7 bits (235), Expect = 1e-19 Identities = 71/238 (29%), Positives = 115/238 (48%), Gaps = 2/238 (0%) Frame = +3 Query: 21 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLT 200 AGK + + S +GA++ LTGRN E L + KD ++ L ADL Sbjct: 6 AGKTILVTGASSGLGKAIAIYFSTVGARVVLTGRNEERLHETLKDMSG-SNHLYFIADLA 64 Query: 201 KESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT-ML 377 K + ++ + G LD +++ AGI +T ++ +D + NTNV+S ++ L Sbjct: 65 KVESTQAMMDTVFANVGALDSVIHCAGIQKTLPLQALKEHHFDDIFNTNVKSAQFIAKFL 124 Query: 378 AVPHLLESKGXXXXXXXXXG-IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554 S+G + P + +Y+ SKA++ ++ +A+ELA + +RVNC+ Sbjct: 125 RKKGRYNSQGTSLVLLSSVAAVCGEPAISSYSASKAALLGLSKSLAIELARQNIRVNCIA 184 Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 PG + TE+ S++ A E H LG GKP+ +A FLASD + ITG Sbjct: 185 PGHVGTEMAIE--FSKQLTAEQRENILLKHPLGL-GKPEYIAQAAEFLASDKSCWITG 239 >UniRef50_A0GDY0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Burkholderia phytofirmans PsJN Length = 249 Score = 98.7 bits (235), Expect = 1e-19 Identities = 63/211 (29%), Positives = 102/211 (48%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA + + GR + + + A+ L T DL + +++ + +G LD+ V N Sbjct: 30 GAHVLIVGRRLAAVNAAVAELGDRATGL--TGDLADPATHDRVASLVEERFGGLDIYVAN 87 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AG+ SL +YD + TN RS+++ + V L + G + F G Sbjct: 88 AGVNTIARSHLVSLEEYDAQVATNTRSVFF-GVQKVASQLRNGGAILLTSSIASSKVFEG 146 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 AY SKA+++ F R ALE +G+RVN ++PG + T + + G++ AF Sbjct: 147 HAAYAGSKAAIEAFARSWALEFKERGIRVNVISPGPVDTPILSKLGIAVADRPAFEAAVA 206 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 E LGR G+ +E+A FL SD +S +TG Sbjct: 207 EKIPLGRLGRAEELAQAALFLVSDESSFVTG 237 >UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Archaeoglobus fulgidus|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Archaeoglobus fulgidus Length = 281 Score = 98.7 bits (235), Expect = 1e-19 Identities = 64/221 (28%), Positives = 112/221 (50%), Gaps = 6/221 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 L+ G + + GR +E L+K+ + +K L++ D+T E D+ ++ +T++ +G++D Sbjct: 55 LADFGCDVVVVGRRLEVLEKLKESIEKLGQRALAVKCDITSEEDVANLVNRTVEEFGRID 114 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 +LVN AGI E L ++++M+ NV ++ + +++ G + Sbjct: 115 ILVNCAGINIPKPAEEYPLEDWNKVMDANVTGVFLVCREVGKVMVKQNG--GKIINVSSV 172 Query: 441 RSFPGV----LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 RS G+ +AY SKA+V+ T+ +A E A + VN + P VI T L E Sbjct: 173 RSSYGMPKNYIAYCSSKAAVNMITKQLACEWAKYNILVNAIAPTVIATPLTAHIMKDPE- 231 Query: 609 YAAFLERT-KETHALGRPGKPDEVAATIAFLASDLASNITG 728 L +T K LGR G PD++ + F ASD ++ +TG Sbjct: 232 ----LSKTMKSRILLGRWGYPDDLIGAVVFFASDASNFVTG 268 >UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family member 4; n=9; Eutheria|Rep: Dehydrogenase/reductase SDR family member 4 - Sus scrofa (Pig) Length = 260 Score = 98.7 bits (235), Expect = 1e-19 Identities = 63/218 (28%), Positives = 116/218 (53%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + ++ R EN+ + V+ + S + K D E+++ ++ +G +D Sbjct: 34 LAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVNLHGGVD 93 Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437 +LV+NA + G I + + +D++++ NV++ +T VP + + G G Sbjct: 94 ILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVG 153 Query: 438 I-RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614 FP + YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T + + + Sbjct: 154 AYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDK---- 209 Query: 615 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 A E KE+ + R G P++ A ++FL S+ AS ITG Sbjct: 210 ARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITG 247 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 98.3 bits (234), Expect = 2e-19 Identities = 65/213 (30%), Positives = 103/213 (48%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDVLVN 272 GA+L L N E + + S + I AD+T E ++ I ID +GK+D+L N Sbjct: 29 GAKLILVDMNEEKGASIEAELKSQGSEAIFIKADVTNEEQVKNIYTTAIDTFGKVDILFN 88 Query: 273 NAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXXXXXGIRSF 449 NAGI E + A++ + + ++ ++ + A+ L++ G G Sbjct: 89 NAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVAQAAIKEFLKAGSGVIVNTASMYGWVGS 148 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 PG AYN +KA V TR + LE A + +RVN + PG I T + L + A + Sbjct: 149 PGSAAYNAAKAGVVNLTRSLGLEYAARNIRVNALCPGFIDTAI-----LGDSDREALINT 203 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 T + R GK +E+A + F+ASD +S +TG Sbjct: 204 T----PMNRLGKSEEMAKAVLFMASDDSSFMTG 232 >UniRef50_Q7UP98 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=4; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Rhodopirellula baltica Length = 273 Score = 98.3 bits (234), Expect = 2e-19 Identities = 72/221 (32%), Positives = 108/221 (48%), Gaps = 6/221 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-----TLSITADLTKESDIEKIIKKTIDHY 248 L+ GA + L RN Q+ S +K A ++ I AD+T E+D+ +++ +D Sbjct: 48 LASAGANVCLVSRNE---QEASAAAEKIAGEYPVRSIGIGADVTVEADVANMVQACVDQL 104 Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-KGXXXXXX 425 LDVL+N+AGI G+I+ SL Q+ ++ +TNV ++ A + ++ G Sbjct: 105 SGLDVLINSAGINVRGSIDELSLEQFRQVQSTNVDGMWLCCKHASSVMKKNGSGRIINLA 164 Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 605 G+ Y SK +V Q TR + LELAP V VN + PG LT + SEE Sbjct: 165 STLGLVGLANRTPYASSKGAVVQMTRALGLELAPHNVTVNAICPGPFLTPMNVPIADSEE 224 Query: 606 QYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + T AL R G+ E+ FLASD +S +TG Sbjct: 225 AKRFIVGAT----ALERWGQMQEIQGAAIFLASDASSYMTG 261 >UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 259 Score = 98.3 bits (234), Expect = 2e-19 Identities = 65/240 (27%), Positives = 119/240 (49%), Gaps = 4/240 (1%) Frame = +3 Query: 21 AGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKV-SKDCDKFASTLSITADL 197 AGKV + GA++++ R+ + + + S+ D + AD+ Sbjct: 10 AGKVAVVSGGAGGCGGAASELFAAQGAKVAIIDRDGDAAETLASRLRDAGLQAIGFGADV 69 Query: 198 TKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTML 377 +K++++++ + + YG D+L N+AG + + +++D LM NV+S++ +T Sbjct: 70 SKQAEVQQAVNAAREQYGNADILFNHAGTLIVKPFLDIEESEWDWLMGVNVKSMFLMTKA 129 Query: 378 AVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554 +P +LE +G + + PG + Y+ +K + F R +A+E +G+R N + Sbjct: 130 VLPQMLEKGRGSIVCTSSISAVCATPGEVLYDATKGACHMFARAIAVEYRDRGIRCNALA 189 Query: 555 PGVILTELQRRGGLSEEQYAAFLERTKETHAL--GRPGKPDEVAATIAFLASDLASNITG 728 PG I T R L + Q A ++ T+ A+ GR +P EVAA FLASD +S + G Sbjct: 190 PGFIRTPHGMR-ELKDLQ-AMGVDATEAAIAVQQGRLCEPSEVAAAALFLASDESSFVNG 247 >UniRef50_Q3WHY3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 346 Score = 98.3 bits (234), Expect = 2e-19 Identities = 63/211 (29%), Positives = 97/211 (45%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 G +++TG+N E L L AD +D + + + D +G LD + N Sbjct: 126 GFAVAITGQNPETLAAARHVLPD--DVLVQRADARVLADADALAAELRDRFGHLDAVFLN 183 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 A + + + + + Y NV+ ++ +P LL G RSFPG Sbjct: 184 AAVAQPSSFSSVTEESYKEHFGVNVKGQFFTLQRVLP-LLRDGGTVVFNSSRLVARSFPG 242 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 + Y +K +V R +A+ELAP+ +RVN V+PG + T + GLS + + Sbjct: 243 MSLYVATKGAVASMARALAVELAPRRIRVNVVSPGPVDTPALAKQGLSAAELTSLRTTLT 302 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 LGR +EVA T+AFL SD AS +TG Sbjct: 303 AKVPLGRIASDEEVAHTVAFLVSDAASYLTG 333 >UniRef50_Q2BK08 Cluster: Pteridine reductase; n=1; Neptuniibacter caesariensis|Rep: Pteridine reductase - Neptuniibacter caesariensis Length = 246 Score = 98.3 bits (234), Expect = 2e-19 Identities = 63/186 (33%), Positives = 99/186 (53%) Frame = +3 Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNV 350 S + +ADL + ++ + + H+G+L++L+NNA IE TSL Q+D L+N+N+ Sbjct: 57 SAKTFSADLNNLEQLNQLAEDILRHFGQLNLLINNASTFYPTPIEETSLHQWDELINSNL 116 Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530 R+ Y+L L ES G R PG Y+I+KA ++ T+ +A ELAP+ Sbjct: 117 RAPYFLCATLSKTLRESNGCIINMIDIHAQRGLPGYPIYSIAKAGLEMLTKSLAKELAPQ 176 Query: 531 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 710 VRVN ++PG IL Q +S + A L++ LGR G +++A +L+ Sbjct: 177 -VRVNGISPGAILWPEQE---VSSTEKANILDKV----LLGRLGVEEDLAQAAIYLSQ-- 226 Query: 711 ASNITG 728 A ITG Sbjct: 227 AEYITG 232 >UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=1; Halothermothrix orenii H 168|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Halothermothrix orenii H 168 Length = 243 Score = 98.3 bits (234), Expect = 2e-19 Identities = 61/190 (32%), Positives = 99/190 (52%), Gaps = 1/190 (0%) Frame = +3 Query: 162 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 341 K +TL + ADLT + K++++ I +G+LD++VN+AGI G IE TS A++++ Sbjct: 44 KGENTLYVKADLTDYNQARKVVEEGIAKFGQLDIVVNSAGITGVGNIETTSPAEFEKQFA 103 Query: 342 TNVRSIYYLTMLAVPHLLESKG-XXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALE 518 NV + AV L + G G++ P +AY SKA+V FT+C+AL+ Sbjct: 104 VNVFGTFNTCKAAVGELKKRPGASIINIASDLGVKPIPDRIAYCPSKAAVVMFTKCMALD 163 Query: 519 LAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFL 698 L P +RVN + PG+ T + + + + E + L R D++A FL Sbjct: 164 LGP-DIRVNAIMPGLTETPMIKDRIEKADDPDQVRKEMAEMYVLKRMCTVDDIANAALFL 222 Query: 699 ASDLASNITG 728 A++ + ITG Sbjct: 223 ATEDSGFITG 232 >UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; Desulfitobacterium hafniense Y51|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 262 Score = 98.3 bits (234), Expect = 2e-19 Identities = 61/216 (28%), Positives = 109/216 (50%), Gaps = 5/216 (2%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLV 269 G L++T R + ++++KD + L I+AD + + DI++++ +T++ +GK+D+L+ Sbjct: 38 GCDLAITSRTPADCERIAKDIETLYGVKCLGISADSSNKDDIDRVVAQTVETFGKIDILI 97 Query: 270 NNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE--SKGXXXXXXXXXGI 440 NNAGI +T + + + + ++NTN++ ++ + + G G+ Sbjct: 98 NNAGISGKTAALLDQTEDDFMNVINTNLKGVFQFAQAVAAQIAKQGKGGRIVNIASVGGL 157 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 V Y SKA V T+ +A E A G+ VN V PG ++TEL + E A Sbjct: 158 IGGKSVAPYGASKAGVLSLTKTMANEWARYGITVNAVCPGYVITELNQDIFADPEIKAKM 217 Query: 621 LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 +RT + R G +EVA + + SD S +TG Sbjct: 218 EKRT----PVRRLGSVEEVAGPVLAMVSDSFSYMTG 249 >UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR; n=28; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 253 Score = 98.3 bits (234), Expect = 2e-19 Identities = 70/220 (31%), Positives = 111/220 (50%), Gaps = 6/220 (2%) Frame = +3 Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLDV 263 ++LGA++ + E Q+V+ + +++ D+T+++ + ++ + +G+LD+ Sbjct: 27 AELGAKVVVADLRAEAAQQVAAAIESAGGQAIAVHVDVTQDASVADMVAAAVKRFGRLDI 86 Query: 264 LVNNAGIIETGT-IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXX-G 437 LVNNAG + T +DR+ TNV+SIY AVP + G G Sbjct: 87 LVNNAGTTHKNQPMLETDEKTFDRVYATNVKSIYLGARHAVPLFRQQGGGVIINIASTAG 146 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR---RGGLSEEQ 608 +R PG+ Y +K + T+ +A+ELAP +RVN +NP + T L G SEE Sbjct: 147 LRPRPGLSWYAGTKGAAITLTKAMAVELAPDKIRVNAINPVMGETGLLADFLPGADSEE- 205 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ T LGR KP ++A AFLASD A ITG Sbjct: 206 ---VRQKIIATIPLGRLSKPIDIAKATAFLASDEADFITG 242 >UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 250 Score = 98.3 bits (234), Expect = 2e-19 Identities = 56/180 (31%), Positives = 88/180 (48%) Frame = +3 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368 AD+T + + + YG+ D+LVNNAG++ I ++DR+ N +S + + Sbjct: 62 ADVTSAVQVATLGQHVRSAYGRADILVNNAGMLSFAPIVGADANEWDRVQKVNCKSAFLM 121 Query: 369 TMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 P L+ KG G++ AY+I+KA + T+ A+EL P G+RVN Sbjct: 122 IRTFAP-LMAGKGAIINISSSAGLKPTANTAAYSIAKAGLLMLTQIAAMELGP-GIRVNA 179 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 + PG + T++ +E E + R G+P E+A +AFLASD AS I G Sbjct: 180 IAPGPLDTDMPHSYLKGHPHKGQIMEHMIERTIVKRLGQPGEIAEVVAFLASDAASYING 239 >UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Dehalococcoides|Rep: Short-chain dehydrogenase/reductase SDR - Dehalococcoides sp. BAV1 Length = 265 Score = 98.3 bits (234), Expect = 2e-19 Identities = 64/222 (28%), Positives = 104/222 (46%), Gaps = 7/222 (3%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + + N+E QK + +I AD++ +D +K+I T+ +G LD Sbjct: 32 LAEAGASIMIPDLNLEVAQKTVAEIKALGGKATAIQADVSNINDTQKVIDATLKAFGDLD 91 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK--GXXXXXXXXX 434 ++VNNAGI + + A +D+ + N++ + + + A ++ +K G Sbjct: 92 IMVNNAGIYRFMPAIDMTEAMWDKTLGINLKGLMFFSQAAAKAMMAAKHGGKIINIASID 151 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILT----ELQRRGGLSE 602 G R + Y+ SK V T+ +A E AP G+ VN V PG I T L G +S Sbjct: 152 GFRPTGNLAHYDASKGGVIMLTKAMAQEWAPHGILVNAVAPGGINTPGASALMPSGSMSA 211 Query: 603 EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 EQ + L R G+PD++ + FL S A I G Sbjct: 212 EQLMELSKSFVAKLPLKRMGEPDDIGKVVLFLTSAAADYIVG 253 >UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=4; Methanosarcina|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Methanosarcina acetivorans Length = 242 Score = 98.3 bits (234), Expect = 2e-19 Identities = 53/170 (31%), Positives = 93/170 (54%), Gaps = 3/170 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC--DKFASTLSITADLTKESDIEKIIKKTIDHYGKL 257 L+K G + + RN E+ K ++D D + I D+ E D+ ++I +TID G+L Sbjct: 31 LAKEGVNIIIAARN-ESESKETQDQLKDMGSKAFEIPVDVRNEEDVRRLISRTIDKCGRL 89 Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXX 434 D+L+NNAG+ +E T++ +YD++++TN++ ++ T A+P+L SK G Sbjct: 90 DILINNAGVALKKRLEETTVEEYDKIIDTNLKGVFLCTKYAIPYLRRSKNGKIINISSIG 149 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 584 G+ P Y SK V+ T +A EL + ++V + PG + T++ R Sbjct: 150 GLHGIPEFSVYCASKFGVNGVTEAIAAELEGQ-IKVYSICPGAVDTDMYR 198 >UniRef50_Q9A872 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=18; Bacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Caulobacter crescentus (Caulobacter vibrioides) Length = 255 Score = 97.9 bits (233), Expect = 2e-19 Identities = 63/220 (28%), Positives = 108/220 (49%), Gaps = 5/220 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263 L+ GA ++ GR+ + + + LSI AD + +++++ +T+ +GK+D+ Sbjct: 29 LAAAGADIAAAGRSAPTETQAAVEA-LGRKFLSIKADFSSIEPVQRVVDETVAAFGKVDI 87 Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXG 437 LVNNAGII S A +D +M+TN++ +++LT L+ +G Sbjct: 88 LVNNAGIIRRADSIEFSEADWDAVMDTNLKVVFFLTQAFAKQALKQGFEGGQAKVINIAS 147 Query: 438 IRSFPG---VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQ 608 + SF G V +Y SK+ + T+ +A E A KG+ VN + PG T +++ Sbjct: 148 LLSFQGGIRVPSYTASKSGLAGLTKILANEWATKGINVNAIAPGYFDTNNTEALRADQDR 207 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 AA L R GR G+P+++ FLAS + + G Sbjct: 208 NAAILARI----PAGRWGRPEDIGGAAVFLASSASDYVQG 243 >UniRef50_Q8RDH9 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 245 Score = 97.9 bits (233), Expect = 2e-19 Identities = 59/191 (30%), Positives = 96/191 (50%), Gaps = 1/191 (0%) Frame = +3 Query: 159 DKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLM 338 + F+ AD++ ++++I + +G++D L+NNAGI + + +DR+M Sbjct: 51 ENFSYAEIFQADISNRKQVDEMIDEIYRKFGRIDYLINNAGIAQIKPFVEITEEDWDRMM 110 Query: 339 NTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515 N N++ ++ T + ++L K G GI + Y+ SK V FT+ +A Sbjct: 111 NVNLKGLFNCTQSVLRYMLPKKQGSIINISSIWGISGASCEVHYSASKGGVIAFTKALAK 170 Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695 EL P +RVNC+ PGVI T + L+ E +E L GKP++VA + F Sbjct: 171 ELGPSKIRVNCIAPGVIDTRMNNI--LNGEDKKHLIEEI----PLMSIGKPEDVANAVLF 224 Query: 696 LASDLASNITG 728 L SD A+ ITG Sbjct: 225 LLSDKANFITG 235 >UniRef50_Q89EA2 Cluster: Gdh protein; n=3; Bradyrhizobium|Rep: Gdh protein - Bradyrhizobium japonicum Length = 278 Score = 97.9 bits (233), Expect = 2e-19 Identities = 62/185 (33%), Positives = 88/185 (47%), Gaps = 3/185 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 362 + AD+ E DI + + + + +LD LVNNAG + + Y R+++ N+ Sbjct: 78 VQADIGSEQDIAAMFETILARWKRLDCLVNNAGFQRESPSDALDVETYRRIIDVNLNGAV 137 Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSF---PGVLAYNISKASVDQFTRCVALELAPKG 533 A+ H + ++G + PG LAY+ISK + TR +ALE A G Sbjct: 138 LCAQKALAHFV-ARGGGGSIINCSSVHQIIPKPGYLAYSISKGGLANLTRTLALEFARHG 196 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 +RVN V PG I T + E+ LGR G P+E+AA AFLASD A Sbjct: 197 IRVNAVGPGAIDTPINAAWTGDPEKRGVVTSHI----PLGRVGTPEEIAAVFAFLASDDA 252 Query: 714 SNITG 728 S ITG Sbjct: 253 SYITG 257 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 97.9 bits (233), Expect = 2e-19 Identities = 64/185 (34%), Positives = 97/185 (52%), Gaps = 6/185 (3%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D+T+E+D ++++ G+LDVLVNNAGI + IE + +DR +N N++S++ Sbjct: 62 DVTQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGC 121 Query: 372 MLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKG--VRVN 545 + + + G I P LAY+ SKA V ++ VAL A KG +RVN Sbjct: 122 KHGLALMKQKGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVALHCAEKGYAIRVN 181 Query: 546 CVNPGVILTEL----QRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 ++PG I T L G L+ ++ A R L R G PDEVA + +LASD + Sbjct: 182 SLHPGYIDTPLLAGSNAGGSLTADEVTASRVRIGGEIPLKRRGTPDEVAGAVLYLASDES 241 Query: 714 SNITG 728 + +TG Sbjct: 242 TYVTG 246 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 97.9 bits (233), Expect = 2e-19 Identities = 59/183 (32%), Positives = 94/183 (51%), Gaps = 4/183 (2%) Frame = +3 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII-ETGTIENTSLAQYDRLMNTNVRSIYYL 368 D+T E+D+ ++ + + H+G+LDVLVNNAGI +LAQ+ R+++ NV ++ Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128 Query: 369 TMLAVPHL-LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN 545 T A+PH+ G GI P V AY+ SKA+V + A+ A K +R N Sbjct: 129 TRAAIPHIDAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAVRMMAKVDAMLYAAKNIRAN 188 Query: 546 CVNPGVILTELQRRG--GLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 V+PG I T + + ++ AF E + + + G P ++AA I +L S Sbjct: 189 SVHPGYIRTPMLEDAFRQMGQDPDRAF-EYMQTNVPMAKIGSPRDIAAGILYLVSPAGRY 247 Query: 720 ITG 728 +TG Sbjct: 248 VTG 250 >UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aurantiacus J-10-fl Length = 249 Score = 97.9 bits (233), Expect = 2e-19 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 4/243 (1%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCD-KFASTLSIT 188 M F GKV L GA + L R +E L+ V + D K A TL++ Sbjct: 1 MEFEGKVALVTGAGTGIGEAIAERLLAGGALVVLVSRRLEPLELVCRRIDPKGARTLALE 60 Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYDRLMNTNVRSIY 362 AD+ +E +K+TI+ +GKLD+ VNNAG+ +++ + +++T++ I+ Sbjct: 61 ADVRNPMAMEAAVKRTIERFGKLDMAVNNAGVTGPAGVPVQDVEAEIWREVIDTDLTGIF 120 Query: 363 YLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539 Y +P +L G G+ G+ AY +K V TR ALELA +R Sbjct: 121 YSMKYEIPAMLANGSGAIVNMSSANGLVGLAGMAAYTAAKHGVIGLTRSAALELAESNIR 180 Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 719 V V PG + T G + A L H + R +EVA +A+L S+ A+ Sbjct: 181 VCAVAPGYVATPRIMDSGKEVTDWMASL------HPMKRLATREEVADFVAYLLSERAAF 234 Query: 720 ITG 728 +TG Sbjct: 235 MTG 237 >UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Ralstonia|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia pickettii 12D Length = 254 Score = 97.9 bits (233), Expect = 2e-19 Identities = 59/187 (31%), Positives = 93/187 (49%) Frame = +3 Query: 168 ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTN 347 A +++ AD++ + ++ + + +G +D+LVNNAGI+E + + LA +D TN Sbjct: 64 AHAIAVQADVSDAASVDAMTGTVREAFGAIDILVNNAGILENQPVGSIDLASFDVQFRTN 123 Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527 S +T +PH+ G R G+ Y SKA+V T A+EL P Sbjct: 124 AFSTILVTQAVLPHVPAPGGRIVNVSSSLVYRPRAGLAVYAASKAAVGALTHAFAVELGP 183 Query: 528 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 707 + + VN V P LT + +E A R +++ LGR +P ++A +AFLASD Sbjct: 184 RNITVNAVAPA--LTRTDMTAPIPDEVKA----RMRDSTPLGRLAEPGDIADAVAFLASD 237 Query: 708 LASNITG 728 A ITG Sbjct: 238 DARWITG 244 >UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 259 Score = 97.9 bits (233), Expect = 2e-19 Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 5/191 (2%) Frame = +3 Query: 171 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 347 + + + D+TKESD++ +I+ T YG +D NNAGI IE G + + ++D +M N Sbjct: 57 NAIFVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEKGELSKGTEDEFDSIMAVN 116 Query: 348 VRSIYYLTMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524 V+ ++ + ++ + G G+ + P + Y SK +V T+ A+E A Sbjct: 117 VKGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVENA 176 Query: 525 PKGVRVNCVNPGVILTELQRRGGL---SEEQYAAFLERTKETHALGRPGKPDEVAATIAF 695 G+R+N V PGVI T + R + SE + R H + R G +E++ + + Sbjct: 177 RNGIRINAVCPGVIDTNMFNRSRMFDRSEVSASETRARVNAIHPMDRIGTAEEISDAVLY 236 Query: 696 LASDLASNITG 728 L SD AS ITG Sbjct: 237 LCSDGASFITG 247 >UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE; n=6; Brucellaceae|Rep: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella melitensis Length = 249 Score = 97.5 bits (232), Expect = 3e-19 Identities = 65/213 (30%), Positives = 113/213 (53%), Gaps = 2/213 (0%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ L NV+ ++ D ++ +SI AD+++++D+E++ + + +G++D++VNN Sbjct: 30 GARVVLADVNVKRVEDGLADIS--SNGISIQADVSRKNDMERVARTAFEEFGRIDIMVNN 87 Query: 276 AGIIETG-TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXXXXXGIRSF 449 AG + + +D ++ N++++YY T L VP + + G G+ Sbjct: 88 AGFTHRNMPLTDVDEHNFDLIVAVNMKALYYSTQLVVPIMEHQGGGVIINTASATGLHPR 147 Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLER 629 G+ Y SK+ V T+ +ALELA + +RVNC+ P E + L+E+ A Sbjct: 148 KGLTWYCASKSWVVSATKAMALELAERNIRVNCLCPAESDGE-GLKMFLAEDTPEA-RAA 205 Query: 630 TKETHALGRPGKPDEVAATIAFLASDLASNITG 728 K T LGR P +VA +LASD AS +TG Sbjct: 206 LKSTIPLGRFSTPKDVAEAALWLASDDASMVTG 238 >UniRef50_Q9REP0 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Zymomonas mobilis Length = 243 Score = 97.5 bits (232), Expect = 3e-19 Identities = 59/184 (32%), Positives = 97/184 (52%) Frame = +3 Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356 LSI AD + +K+I +T H+G++DVLV NAG++ I+ S+ + ++N N+RS Sbjct: 56 LSIQADGSTVEGNKKVISETAKHFGRVDVLVCNAGMLSYKNIDQVSVDDINDMLNLNLRS 115 Query: 357 IYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGV 536 + AV HL G F G+ Y+ +KA + F + VA +L K + Sbjct: 116 VMVEVSEAVRHLPSGGRIILIGSTFAGRAPFAGISLYSAAKAGLRGFAKGVARDLGQKAI 175 Query: 537 RVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLAS 716 +N + PG I T++ G + + ++F TK+ G+ D++A T++FLAS + Sbjct: 176 TINVIEPGPINTDMNPADGEAFDLISSF-TATKDY------GQVDDIARTVSFLASSESG 228 Query: 717 NITG 728 NITG Sbjct: 229 NITG 232 >UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|Rep: FabG3_1 - Roseovarius sp. HTCC2601 Length = 249 Score = 97.5 bits (232), Expect = 3e-19 Identities = 70/241 (29%), Positives = 119/241 (49%), Gaps = 2/241 (0%) Frame = +3 Query: 12 MNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA 191 M+ GKVV ++ GA + L + ++ +++D A L++ Sbjct: 1 MDVTGKVVLISGAARGMGAHEARRFAEAGACVILGDVLDDEVRALAEDLGD-ARALAVPL 59 Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371 D+++ D E + + +G++DVLVNNAGI+ IE S +++++++ N+ + Sbjct: 60 DVSRSEDWEGAVAAGVARFGQIDVLVNNAGILRFSNIETCSDEEWEKVLSINLGGAFKGI 119 Query: 372 MLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNC 548 +P + + G G+++F GV AY SK + TR A+ELA G+RVN Sbjct: 120 RAVLPVMKRNGSGSIINISSTAGLKAFGGVSAYVTSKFGIRGLTRAAAVELAGHGIRVNS 179 Query: 549 VNPGVILTELQRRGGLSEEQYAAFLERTKETHA-LGRPGKPDEVAATIAFLASDLASNIT 725 V+PG I T+ + E+ Y F H + R G+PDE+A + +LASD +S T Sbjct: 180 VHPGNIDTD------MVEDLYPNF------NHVPMKRMGQPDEIANLVIYLASDASSFST 227 Query: 726 G 728 G Sbjct: 228 G 228 >UniRef50_A6UBN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 253 Score = 97.5 bits (232), Expect = 3e-19 Identities = 66/211 (31%), Positives = 100/211 (47%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GA++ LTGR+ N+ ++ ++ LS +D+ +DI + G +D+L N Sbjct: 30 GAEVLLTGRSESNIARIREEFGPRVHALS--SDIAHLNDIAILGAAAGQKLGAIDLLHIN 87 Query: 276 AGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPG 455 AGI E + S A YDR + N + ++ P L+ G G Sbjct: 88 AGISELEPFDQVSEASYDRQFSVNTKGAFFTVQRLAP-LIREGGSIVFTSSVADEGGHQG 146 Query: 456 VLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTK 635 + Y+ SKA++ F +A EL P+G+RVN V+PG I T + GL+E Q A F Sbjct: 147 MSVYSASKAALVSFASVLAAELLPRGIRVNSVSPGFIDTPTKGAAGLTEAQRAEFKALGD 206 Query: 636 ETHALGRPGKPDEVAATIAFLASDLASNITG 728 + R G DEVA + FLA + A+ TG Sbjct: 207 AITPMRRNGTADEVARAVLFLAFE-ATFTTG 236 >UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - unidentified eubacterium SCB49 Length = 256 Score = 97.5 bits (232), Expect = 3e-19 Identities = 58/185 (31%), Positives = 98/185 (52%), Gaps = 3/185 (1%) Frame = +3 Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAG-IIETGTIENTSLAQYDRLMNTNVRSI 359 I+ DLTKE+D ++K+T++ G LD+L+NNAG ++ + + ++M+ N+ S+ Sbjct: 64 ISGDLTKEADANTLVKQTVEALGGLDILINNAGSLVARKLLSEMETEFWHKVMDINLTSM 123 Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRS--FPGVLAYNISKASVDQFTRCVALELAPKG 533 ++T A P+L +++ R PG L Y+ SK ++ FTR ++ EL +G Sbjct: 124 MFVTRAASPYLAKNENSSIVNLASLAGRKGGHPGSLVYSTSKGAILTFTRALSTELGAQG 183 Query: 534 VRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLA 713 +RVN V+PG+IL ++E A T + R G +VA + +LAS+ Sbjct: 184 IRVNAVSPGLILGTSFHNTHTTKESAA----ETTAGIPIQRAGNAADVARAVLYLASEYD 239 Query: 714 SNITG 728 ITG Sbjct: 240 GFITG 244 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 97.5 bits (232), Expect = 3e-19 Identities = 59/220 (26%), Positives = 112/220 (50%), Gaps = 5/220 (2%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDC-DKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA++ ++ + E +KV + + + I D+ KE + + +I+ T++ YGKL Sbjct: 26 LAREGAKIVVSDIDEEGGKKVVQQIKEDGGEAIFIKQDVAKEDEWKNVIETTLETYGKLH 85 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL--LESKGXXXXXXXXX 434 +L N+AGI GT+E+ +L + L++ N+ + T + + + G Sbjct: 86 ILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGTKYGIKGMRKTDEGGSIINFSSIE 145 Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPK--GVRVNCVNPGVILTELQRRGGLSEEQ 608 G+ P + AYN SK V FT+ AL A + G+R+N ++P I T + ++ Sbjct: 146 GLIGDPNLPAYNASKGGVTIFTKSAALHCAKQGYGIRINSIHPAYIWTPMVENFLKAQGD 205 Query: 609 YAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 ++ + H +G G+PD++ + +LASD + +TG Sbjct: 206 VEEGKKQLESLHPIGHLGEPDDIGYGVVYLASDESKFMTG 245 >UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR; n=8; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 256 Score = 97.5 bits (232), Expect = 3e-19 Identities = 61/218 (27%), Positives = 109/218 (50%), Gaps = 3/218 (1%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAS-TLSITADLTKESDIEKIIKKTIDHYGKLD 260 L++ GA + L GR E L+ + D + +++ D+TK + ++ T+ +G+LD Sbjct: 29 LAEHGADVVLAGRREEPLKATAADVEALGRRAIAVPTDVTKADQCQALVDATLGEFGRLD 88 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV-PHLLESKGXXXXXXXXXG 437 VL+NNAG ET ++ + ++ ++ N+ S +YL+ A P + + KG Sbjct: 89 VLLNNAGGGETKSLMKWTDEEWHEVLELNLSSAWYLSRAAAKPMIAQGKGAIVNISSGAS 148 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 + + P Y +KA ++ T +A KGVRVNC+ G I T G ++ + Sbjct: 149 LLAMPQAPVYAAAKAGLNNLTGSMAAAWTRKGVRVNCIACGAIRTP----GLEADAKRQG 204 Query: 618 F-LERTKETHALGRPGKPDEVAATIAFLASDLASNITG 728 F ++ +T+ GR + DE+ + F ASD +S +G Sbjct: 205 FDIDMIGQTNGSGRIAEADEIGYGVLFFASDASSYCSG 242 >UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinobacter sp. ELB17 Length = 264 Score = 97.5 bits (232), Expect = 3e-19 Identities = 72/220 (32%), Positives = 107/220 (48%), Gaps = 9/220 (4%) Frame = +3 Query: 96 GAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275 GAQ+ + + L + + A L D+ E+ +++++ +D +GK+D+L N Sbjct: 30 GAQVIMADTSELGLAETGNLMPEGAEYLRRLVDVADEAQVKELVSDAMDAFGKIDILCNI 89 Query: 276 AGIIETG-----TIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXG 437 AGI TG IEN ++D++++ N+ L PH+ K G G Sbjct: 90 AGIASTGKGHPPVIENER-DEWDKVLSVNLIGTMLLIKHVAPHMQARKLGSIVNTASIAG 148 Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617 IRS G AY+ SKA V T A +L +RVN V PG++ T + R + YA Sbjct: 149 IRSGAGGNAYSASKAGVINLTMTAACDLGDHNIRVNAVCPGLVETGMTR----AVFDYAR 204 Query: 618 FLERTKETHA---LGRPGKPDEVAATIAFLASDLASNITG 728 E+ + A L R G P+E+AA I F ASD AS ITG Sbjct: 205 THEKAHKLGARCELRRYGDPEEIAAAILFFASDDASYITG 244 >UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=2; Bacteria|Rep: Predicted short chain dehydrogenase - Bacillus sp. B14905 Length = 251 Score = 97.5 bits (232), Expect = 3e-19 Identities = 67/217 (30%), Positives = 104/217 (47%), Gaps = 2/217 (0%) Frame = +3 Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFA-STLSITADLTKESDIEKIIKKTIDHYGKLD 260 ++K GA +++ N E + + KD + + ++ + A+L + + KII ++ YGKLD Sbjct: 26 MAKEGAIVTIVDLNAEAGEAMEKDLQQISPKSMFLQANLMERDQLPKIIDTVVEKYGKLD 85 Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGI 440 VLVNNA + TIE T+ A D T +YL A+PHL E++G GI Sbjct: 86 VLVNNAHAAKQVTIEETTQADLDLSFGTGFYPTFYLMQAALPHLKETQGNIINFASGAGI 145 Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620 + AY +K ++ +R A E G+ VN ++P +Q E Y Sbjct: 146 QGHETQAAYAAAKEAIRGISRVAANEWGRYGINVNIISPLADSPGVQAWAKAQPEYY--- 202 Query: 621 LERTKETHALGRPGKPDEVAATIA-FLASDLASNITG 728 E + LGR G ++ +A FLASD + ITG Sbjct: 203 -EAVRNKIPLGRFGHIEQDIGRVAVFLASDDSQYITG 238 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 705,861,424 Number of Sequences: 1657284 Number of extensions: 14114608 Number of successful extensions: 46276 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 40860 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 42464 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 58853922985 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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