Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0982
(733 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BX641106-1|CAE46049.1| 321|Homo sapiens hypothetical protein pr... 165 1e-40
AK131551-1|BAD18685.1| 577|Homo sapiens protein ( Homo sapiens ... 165 1e-40
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein. 162 1e-39
AF140674-1|AAD56357.1| 860|Homo sapiens zinc metalloprotease AD... 162 1e-39
AB209685-1|BAD92922.1| 530|Homo sapiens a disintegrin and metal... 162 1e-39
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 146 5e-35
AY358122-1|AAQ88489.1| 877|Homo sapiens ENWT2803 protein. 144 3e-34
AL356356-13|CAI15500.2| 1074|Homo sapiens ADAMTS-like 4 protein. 144 3e-34
AL356356-12|CAI15499.1| 877|Homo sapiens ADAMTS-like 4 protein. 144 3e-34
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein. 140 5e-33
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w... 139 8e-33
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ... 138 2e-32
AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease AD... 137 4e-32
BC040620-1|AAH40620.1| 356|Homo sapiens ADAMTSL5 protein protein. 124 3e-28
AK131571-1|BAD18703.1| 471|Homo sapiens protein ( Homo sapiens ... 124 3e-28
AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and ... 123 6e-28
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte... 123 8e-28
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein. 123 8e-28
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida... 119 9e-27
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w... 118 2e-26
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein. 118 2e-26
BC109114-1|AAI09115.1| 950|Homo sapiens ADAM metallopeptidase w... 107 3e-23
AJ315733-1|CAC86014.1| 950|Homo sapiens metalloprotease disinte... 107 3e-23
BX649571-2|CAI18773.1| 951|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
BX649571-1|CAM26559.1| 1060|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
BX629352-2|CAI23592.1| 951|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
BX629352-1|CAM28356.1| 1060|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
BX324209-2|CAI17317.1| 951|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
BX324209-1|CAM24586.1| 1060|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
BC050544-1|AAH50544.1| 951|Homo sapiens ADAMTS-like 2 protein. 107 4e-23
AB011177-1|BAA25531.2| 1031|Homo sapiens KIAA0605 protein protein. 107 4e-23
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein. 106 7e-23
BC063293-1|AAH63293.1| 837|Homo sapiens ADAM metallopeptidase w... 105 2e-22
AY044847-1|AAL02262.1| 837|Homo sapiens aggrecanase 1 protein. 103 9e-22
AL590714-6|CAH72146.1| 837|Homo sapiens ADAM metallopeptidase w... 103 9e-22
AY358886-1|AAQ89245.1| 837|Homo sapiens ADAMTS4 protein. 102 1e-21
AF148213-1|AAD41494.1| 837|Homo sapiens aggrecanase-1 protein. 102 1e-21
AB014588-1|BAA31663.2| 849|Homo sapiens KIAA0688 protein protein. 102 1e-21
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 95 3e-19
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein. 93 7e-19
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w... 93 7e-19
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein. 93 7e-19
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w... 93 9e-19
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ... 93 9e-19
AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin metalloprot... 93 9e-19
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein. 93 9e-19
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 93 1e-18
AF237652-1|AAK15041.1| 766|Homo sapiens a disintegrin-like and ... 91 3e-18
AK092324-1|BAC03862.1| 296|Homo sapiens protein ( Homo sapiens ... 89 2e-17
BC113874-1|AAI13875.1| 676|Homo sapiens ADAMTS8 protein protein. 88 4e-17
BC089435-1|AAH89435.1| 918|Homo sapiens ADAMTS8 protein protein. 87 5e-17
AF060153-1|AAD48081.1| 890|Homo sapiens METH2 protein protein. 87 5e-17
AB209717-1|BAD92954.1| 418|Homo sapiens ADAMTS-8 precursor vari... 87 5e-17
BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase w... 84 4e-16
AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with th... 84 4e-16
AL162080-1|CAB82413.1| 550|Homo sapiens hypothetical protein pr... 84 4e-16
AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease ... 84 4e-16
AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with ... 84 4e-16
AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein. 84 4e-16
AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein. 84 4e-16
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein... 83 8e-16
AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein. 81 4e-15
AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and ... 81 4e-15
AF141293-1|AAF02493.1| 518|Homo sapiens ADAMTS5 protein protein. 81 5e-15
BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase w... 77 5e-14
BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase w... 77 5e-14
AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein. 77 5e-14
AP001697-2|BAA95503.1| 517|Homo sapiens disintegrin-like and me... 77 7e-14
BC094811-1|AAH94811.1| 602|Homo sapiens ADAMTSL4 protein protein. 76 1e-13
BC071852-1|AAH71852.1| 602|Homo sapiens ADAMTSL4 protein protein. 76 1e-13
AK131414-1|BAD18561.1| 493|Homo sapiens protein ( Homo sapiens ... 75 2e-13
BC030262-1|AAH30262.1| 439|Homo sapiens ADAMTS-like 1 protein. 74 6e-13
AY358327-1|AAQ88693.1| 525|Homo sapiens ADAMTSL1 protein. 74 6e-13
AL353895-1|CAI14851.1| 525|Homo sapiens ADAMTS-like 1 protein. 74 6e-13
AF176313-1|AAK84170.1| 525|Homo sapiens ADAM-TS related protein... 74 6e-13
AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens ... 72 2e-12
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w... 72 2e-12
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte... 72 2e-12
AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein. 70 8e-12
AK131403-1|BAD18550.1| 415|Homo sapiens protein ( Homo sapiens ... 68 3e-11
AL358817-5|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w... 67 5e-11
AL358817-4|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w... 67 5e-11
AL355344-5|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w... 67 5e-11
AL355344-4|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w... 67 5e-11
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte... 67 5e-11
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein. 67 5e-11
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ... 67 5e-11
AY358118-1|AAQ88485.1| 1097|Homo sapiens ADAMTS13 protein. 67 7e-11
BC042057-1|AAH42057.1| 129|Homo sapiens PAPLN protein protein. 66 1e-10
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w... 66 2e-10
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c... 66 2e-10
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ... 66 2e-10
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ... 66 2e-10
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w... 66 2e-10
AL158826-24|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ... 66 2e-10
AL158826-23|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ... 66 2e-10
AL158826-22|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ... 66 2e-10
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari... 66 2e-10
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein. 66 2e-10
AJ011374-1|CAB66157.1| 364|Homo sapiens hypothetical protein pr... 66 2e-10
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein. 66 2e-10
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c... 66 2e-10
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein. 61 5e-09
AK128469-1|BAC87455.1| 327|Homo sapiens protein ( Homo sapiens ... 59 1e-08
BC139833-1|AAI39834.1| 240|Homo sapiens ADAMTSL5 protein protein. 49 2e-05
BC119796-1|AAI19797.1| 131|Homo sapiens ADAMTSL5 protein protein. 49 2e-05
AY358143-1|AAQ88510.1| 219|Homo sapiens FVSY9334 protein. 42 0.003
AL031658-2|CAI42577.1| 234|Homo sapiens tubulin tyrosine ligase... 33 1.1
CR456466-1|CAG30352.1| 1211|Homo sapiens dJ402G11.8 protein. 31 4.3
BC150137-1|AAI50138.1| 1165|Homo sapiens MOV10L1 protein protein. 31 4.3
AL034546-1|CAI23226.1| 1211|Homo sapiens protein ( Human DNA seq... 31 4.3
AL022328-1|CAI42752.1| 1211|Homo sapiens protein ( Human DNA seq... 31 4.3
AF285604-1|AAK31983.1| 1211|Homo sapiens MOV10-like 1 protein. 31 4.3
>BX641106-1|CAE46049.1| 321|Homo sapiens hypothetical protein
protein.
Length = 321
Score = 165 bits (402), Expect = 1e-40
Identities = 93/225 (41%), Positives = 126/225 (56%), Gaps = 17/225 (7%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C+G R+Y CNT C + R QC+S++ +PF GRFY W P+ V GN C LNC+
Sbjct: 89 CIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQ 148
Query: 227 PMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR----- 388
MG +FY + V DGTPC Q+G AICV G CK IG + L GS+ +CG
Sbjct: 149 AMGYRFYVRQAEKVIDGTPCDQNGT-AICVSGQCKSIGCDDYL-GSDKVVDKCGVCGGDN 206
Query: 389 ---RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
++VSG+F LGY V +P GA +IN+TE+ S NY+ALR + I+NG +A
Sbjct: 207 TGCQVVSGVFKHALTSLGYHRVVEIPEGATKINITEMYKSNNYLALRSRSGRSIINGNWA 266
Query: 560 VSAPGMYEAAGAIFLYTR------TAGLDNVHANGPIYHPIDIMI 676
+ PG YE G +F Y R TAG ++ A GP +D+ +
Sbjct: 267 IDRPGKYEGGGTMFTYKRPNEISSTAG-ESFLAEGPTNEILDVYV 310
>AK131551-1|BAD18685.1| 577|Homo sapiens protein ( Homo sapiens
cDNA FLJ16791 fis, clone TBAES2004105, weakly similar
to ADAM-TS 6 precursor (EC 3.4.24.-). ).
Length = 577
Score = 165 bits (402), Expect = 1e-40
Identities = 93/230 (40%), Positives = 128/230 (55%), Gaps = 17/230 (7%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C+G R+Y CNT C + R QC+S++ +PF GRFY W P+ V GN C LNC+
Sbjct: 291 CIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQ 350
Query: 227 PMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR----- 388
MG +FY + V DGTPC Q+G AICV G CK IG + L GS+ +CG
Sbjct: 351 AMGYRFYVRQAEKVIDGTPCDQNGT-AICVSGQCKSIGCDDYL-GSDKVVDKCGVCGGDN 408
Query: 389 ---RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
++VSG+F LGY V + GA +IN+TE+ S NY+ALR + I+NG +A
Sbjct: 409 TGCQVVSGVFKHALTSLGYHRVVEISEGATKINITEMYKSNNYLALRSRSGRSIINGNWA 468
Query: 560 VSAPGMYEAAGAIFLYTR------TAGLDNVHANGPIYHPIDIMILYTHP 691
+ PG YE G +F Y R TAG ++ A GP +D+ +++ P
Sbjct: 469 IDRPGKYEGGGTMFTYKRPNEISSTAG-ESFLAEGPTNEILDVYMIHQQP 517
>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
Length = 1117
Score = 162 bits (393), Expect = 1e-39
Identities = 89/222 (40%), Positives = 121/222 (54%), Gaps = 11/222 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNA-PCALNC 223
K CLG +RY CNT PC G + R +QC+ FD PFRG++Y W PY G PCALNC
Sbjct: 595 KYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNC 654
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC------ 382
G FY + V DGT C D L IC+ G CK +G +++L GS++RE RC
Sbjct: 655 LAEGYNFYTERAPAVIDGTQCNADSLD-ICINGECKHVGCDNIL-GSDAREDRCRVCGGD 712
Query: 383 GRR--LVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEF 556
G + G F+ GY V +PRG+ I V E+A S+NYIAL+ Y +NG +
Sbjct: 713 GSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAW 772
Query: 557 AVSAPGMYEAAGAIFLYTR-TAGLDNVHANGPIYHPIDIMIL 679
+ P ++ AG F Y R T +++ A GP + +M+L
Sbjct: 773 TIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVL 814
>AF140674-1|AAD56357.1| 860|Homo sapiens zinc metalloprotease ADAMTS6
protein.
Length = 860
Score = 162 bits (393), Expect = 1e-39
Identities = 89/222 (40%), Positives = 121/222 (54%), Gaps = 11/222 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNA-PCALNC 223
K CLG +RY CNT PC G + R +QC+ FD PFRG++Y W PY G PCALNC
Sbjct: 547 KYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNC 606
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC------ 382
G FY + V DGT C D L IC+ G CK +G +++L GS++RE RC
Sbjct: 607 LAEGYNFYTERAPAVIDGTQCNADSLD-ICINGECKHVGCDNIL-GSDAREDRCRVCGGG 664
Query: 383 GRR--LVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEF 556
G + G F+ GY V +PRG+ I V E+A S+NYIAL+ Y +NG +
Sbjct: 665 GSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAW 724
Query: 557 AVSAPGMYEAAGAIFLYTR-TAGLDNVHANGPIYHPIDIMIL 679
+ P ++ AG F Y R T +++ A GP + +M+L
Sbjct: 725 TIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVL 766
>AB209685-1|BAD92922.1| 530|Homo sapiens a disintegrin and
metalloprotease with thrombospondin motifs-6 variant
protein.
Length = 530
Score = 162 bits (393), Expect = 1e-39
Identities = 89/222 (40%), Positives = 121/222 (54%), Gaps = 11/222 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNA-PCALNC 223
K CLG +RY CNT PC G + R +QC+ FD PFRG++Y W PY G PCALNC
Sbjct: 8 KYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNC 67
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC------ 382
G FY + V DGT C D L IC+ G CK +G +++L GS++RE RC
Sbjct: 68 LAEGYNFYTERAPAVIDGTQCNADSLD-ICINGECKHVGCDNIL-GSDAREDRCRVCGGD 125
Query: 383 GRR--LVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEF 556
G + G F+ GY V +PRG+ I V E+A S+NYIAL+ Y +NG +
Sbjct: 126 GSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAW 185
Query: 557 AVSAPGMYEAAGAIFLYTR-TAGLDNVHANGPIYHPIDIMIL 679
+ P ++ AG F Y R T +++ A GP + +M+L
Sbjct: 186 TIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVL 227
>AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein
protein.
Length = 1235
Score = 146 bits (355), Expect = 5e-35
Identities = 84/231 (36%), Positives = 113/231 (48%), Gaps = 12/231 (5%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCA 214
R C+G R + C T+ C G + RAEQC+ FD F+GR Y W+PY C
Sbjct: 58 RDGGSSCVGPARSHRSCRTESCPDGARDFRAEQCAEFDGAEFQGRRYRWLPYYSAPNKCE 117
Query: 215 LNCRPMGQQF-YATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRE--LRCG 385
LNC P G+ F Y V DGTPC + G +CV G+C+V+G + L S + LRCG
Sbjct: 118 LNCIPKGENFYYKHREAVVDGTPC-EPGKRDVCVDGSCRVVGCDHELDSSKQEDKCLRCG 176
Query: 386 R-----RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNG 550
V+G F L GY + VP GA I + E A+S N++A++ Y LNG
Sbjct: 177 GDGTTCYPVAGTFDANDLSRGYNQILIVPMGATSILIDEAAASRNFLAVKNVRGEYYLNG 236
Query: 551 EFAVSAPGMYEAAGAIFLYTRTAGLD----NVHANGPIYHPIDIMILYTHP 691
+ + A AA I Y R A D +HA GP P+ I ++ P
Sbjct: 237 HWTIEAARALPAASTILHYERGAEGDLAPERLHARGPTSEPLVIELISQEP 287
>AY358122-1|AAQ88489.1| 877|Homo sapiens ENWT2803 protein.
Length = 877
Score = 144 bits (349), Expect = 3e-34
Identities = 84/225 (37%), Positives = 115/225 (51%), Gaps = 15/225 (6%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C G + C+ PC + RA QC++F+ + F G+ Y W P+ V G+ C LNCR
Sbjct: 364 CSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELNCR 423
Query: 227 PMGQQFYAT-LSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR----- 388
P G +FY V DGT C Q G P ICV G C G + +L GS R CG
Sbjct: 424 PRGFRFYVRHTEKVQDGTLC-QPGAPDICVAGRCLSPGCDGIL-GSGRRPDGCGVCGGDD 481
Query: 389 ---RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
RLVSG + PLGY + +P GA R+ + +L S NY+ALR I+NG +A
Sbjct: 482 STCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWA 541
Query: 560 VSAPGMYEAAGAIFLYTR----TAGLDNVHANGPIYHPIDIMILY 682
V PG Y A G +F Y R +++ A GP P+D+ +++
Sbjct: 542 VDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIF 586
>AL356356-13|CAI15500.2| 1074|Homo sapiens ADAMTS-like 4 protein.
Length = 1074
Score = 144 bits (349), Expect = 3e-34
Identities = 84/225 (37%), Positives = 115/225 (51%), Gaps = 15/225 (6%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C G + C+ PC + RA QC++F+ + F G+ Y W P+ V G+ C LNCR
Sbjct: 364 CSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELNCR 423
Query: 227 PMGQQFYAT-LSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR----- 388
P G +FY V DGT C Q G P ICV G C G + +L GS R CG
Sbjct: 424 PRGFRFYVRHTEKVQDGTLC-QPGAPDICVAGRCLSPGCDGIL-GSGRRPDGCGVCGGDD 481
Query: 389 ---RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
RLVSG + PLGY + +P GA R+ + +L S NY+ALR I+NG +A
Sbjct: 482 STCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWA 541
Query: 560 VSAPGMYEAAGAIFLYTR----TAGLDNVHANGPIYHPIDIMILY 682
V PG Y A G +F Y R +++ A GP P+D+ +++
Sbjct: 542 VDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIF 586
>AL356356-12|CAI15499.1| 877|Homo sapiens ADAMTS-like 4 protein.
Length = 877
Score = 144 bits (349), Expect = 3e-34
Identities = 84/225 (37%), Positives = 115/225 (51%), Gaps = 15/225 (6%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C G + C+ PC + RA QC++F+ + F G+ Y W P+ V G+ C LNCR
Sbjct: 364 CSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELNCR 423
Query: 227 PMGQQFYAT-LSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR----- 388
P G +FY V DGT C Q G P ICV G C G + +L GS R CG
Sbjct: 424 PRGFRFYVRHTEKVQDGTLC-QPGAPDICVAGRCLSPGCDGIL-GSGRRPDGCGVCGGDD 481
Query: 389 ---RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
RLVSG + PLGY + +P GA R+ + +L S NY+ALR I+NG +A
Sbjct: 482 STCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWA 541
Query: 560 VSAPGMYEAAGAIFLYTR----TAGLDNVHANGPIYHPIDIMILY 682
V PG Y A G +F Y R +++ A GP P+D+ +++
Sbjct: 542 VDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIF 586
>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
Length = 1686
Score = 140 bits (339), Expect = 5e-33
Identities = 79/221 (35%), Positives = 114/221 (51%), Gaps = 11/221 (4%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCRPM 232
C+G +R+ CN Q C G + R QCS FD ++G+ +TW+P V+ PC L+CRP
Sbjct: 577 CVGERKRFRLCNLQACPAGXPSFRHVQCSHFDAMLYKGQLHTWVPVVNDVNPCELHCRPA 636
Query: 233 GQQFYATL-SIVDDGTPCTQ-DGLPAICVQGTCKVIGRESVLAGSNSRELRCG------- 385
+ F L V DGTPC Q +C+ G CK +G + + S + E RCG
Sbjct: 637 NEYFAEKLRDAVVDGTPCYQVRASRDLCINGICKNVGCDFEI-DSGAMEDRCGVCHGNGS 695
Query: 386 -RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSN-SSYILNGEFA 559
VSG F + LGY V +P GA I + E+A + N++ALR + Y LNG +
Sbjct: 696 TCHTVSGTFEEAE-GLGYVDVGLIPAGAREIRIQEVAEAANFLALRSEDPEKYFLNGGWT 754
Query: 560 VSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMILY 682
+ G Y+ AG F Y R +N+ + GP P+ I +L+
Sbjct: 755 IQWNGDYQVAGTTFTYARRGNWENLTSPGPTKEPVWIQLLF 795
>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 7 protein.
Length = 1686
Score = 139 bits (337), Expect = 8e-33
Identities = 79/221 (35%), Positives = 114/221 (51%), Gaps = 11/221 (4%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCRPM 232
C+G +R+ CN Q C G + R QCS FD ++G+ +TW+P V+ PC L+CRP
Sbjct: 577 CVGERKRFRLCNLQACPAGRPSFRHVQCSHFDAMLYKGQLHTWVPVVNDVNPCELHCRPA 636
Query: 233 GQQFYATL-SIVDDGTPCTQ-DGLPAICVQGTCKVIGRESVLAGSNSRELRCG------- 385
+ F L V DGTPC Q +C+ G CK +G + + S + E RCG
Sbjct: 637 NEYFAEKLRDAVVDGTPCYQVRASRDLCINGICKNVGCDFEI-DSGAMEDRCGVCHGNGS 695
Query: 386 -RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSN-SSYILNGEFA 559
VSG F + LGY V +P GA I + E+A + N++ALR + Y LNG +
Sbjct: 696 TCHTVSGTFEEAE-GLGYVDVGLIPAGAREIRIQEVAEAANFLALRSEDPEKYFLNGGWT 754
Query: 560 VSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMILY 682
+ G Y+ AG F Y R +N+ + GP P+ I +L+
Sbjct: 755 IQWNGDYQVAGTTFTYARRGNWENLTSPGPTKEPVWIQLLF 795
>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 1593
Score = 138 bits (334), Expect = 2e-32
Identities = 78/222 (35%), Positives = 109/222 (49%), Gaps = 10/222 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCR 226
K C G +RY CN PC R QCS FD P++ Y W P + PC L CR
Sbjct: 579 KYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFPIFNPAHPCELYCR 638
Query: 227 PMGQQF-YATLSIVDDGTPCTQDGLPA-ICVQGTCKVIGRESVLAGSNSRELRCGRRLVS 400
P+ QF L V DGTPC + G +C+ G CK++G + + SN+ E RCG L
Sbjct: 639 PIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGICKMVGCDYEI-DSNATEDRCGVCLGD 697
Query: 401 G-------LFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSN-SSYILNGEF 556
G K + GY + +P+GA I V E+ + N++A+R + Y LNG F
Sbjct: 698 GSSCQTVRKMFKQKEGSGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGF 757
Query: 557 AVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMILY 682
+ G Y+ AG +F Y R L+ + A GP + I +L+
Sbjct: 758 IIQWNGNYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLF 799
>AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease ADAMTS7
protein.
Length = 997
Score = 137 bits (331), Expect = 4e-32
Identities = 78/219 (35%), Positives = 112/219 (51%), Gaps = 11/219 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCRPM 232
C+G +R+ CN Q C G + R QCS FD ++G+ +TW+P V+ PC L+CRP
Sbjct: 577 CVGERKRFRLCNLQACPAGRPSFRHVQCSHFDAMLYKGQLHTWVPVVNDVNPCELHCRPA 636
Query: 233 GQQFYATL-SIVDDGTPCTQ-DGLPAICVQGTCKVIGRESVLAGSNSRELRCG------- 385
+ F L V DGTPC Q +C+ G CK +G + + S + E RCG
Sbjct: 637 NEYFAKKLRDAVVDGTPCYQVRASRDLCINGICKNVGCDFEI-DSGAMEDRCGVCHGNGS 695
Query: 386 -RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSN-SSYILNGEFA 559
VSG F + LGY V +P GA I + E+A + N++ALR + Y LNG +
Sbjct: 696 TCHTVSGTFEEAE-GLGYVDVGLIPAGAREIRIQEVAEAANFLALRSEDPEKYFLNGGWT 754
Query: 560 VSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMI 676
+ G Y+ AG F Y R +N+ + GP P+ I +
Sbjct: 755 IQWNGDYQVAGTTFTYARRGNWENLTSPGPTKEPVWIQV 793
>BC040620-1|AAH40620.1| 356|Homo sapiens ADAMTSL5 protein protein.
Length = 356
Score = 124 bits (299), Expect = 3e-28
Identities = 78/224 (34%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRG--RFYTWIPYVDGNAPCALNCR 226
C G Y C C G + R QC+ ++ RP G + Y W+P+ C LNC
Sbjct: 71 CWGDSHEYRLCQLPDCPPGAVPFRDLQCALYNGRPVLGTQKTYQWVPFHGAPNQCDLNCL 130
Query: 227 PMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR------ 388
G FY + V DGT C+ G +CV G C G + +L GS + E RCGR
Sbjct: 131 AEGHAFYHSFGRVLDGTACSP-GAQGVCVAGRCLSAGCDGLL-GSGALEDRCGRCGGAND 188
Query: 389 --RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFAV 562
V +F GY V +P GA I V S N++AL + Y+LNG + V
Sbjct: 189 SCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRVEH--RSRNHLALMGGDGRYVLNGHWVV 246
Query: 563 SAPGMYEAAGAIFLYTRTAG-LDNVHANGPIYHPIDIMILYTHP 691
S PG YEAAG +YTR G + + A GP H + + +L P
Sbjct: 247 SPPGTYEAAGTHVVYTRDTGPQETLQAAGPTSHDLLLQVLLQEP 290
>AK131571-1|BAD18703.1| 471|Homo sapiens protein ( Homo sapiens
cDNA FLJ16825 fis, clone UTERU2036507, weakly similar
to ADAM-TS 6 precursor (EC 3.4.24.-). ).
Length = 471
Score = 124 bits (299), Expect = 3e-28
Identities = 78/224 (34%), Positives = 104/224 (46%), Gaps = 11/224 (4%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRG--RFYTWIPYVDGNAPCALNCR 226
C G Y C C G + R QC+ ++ RP G + Y W+P+ C LNC
Sbjct: 71 CWGDSHEYRLCQLPDCPPGAVPFRDLQCALYNGRPVLGTQKTYQWVPFHGAPNQCDLNCL 130
Query: 227 PMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR------ 388
G FY + V DGT C+ G +CV G C G + +L GS + E RCGR
Sbjct: 131 AEGHAFYHSFGRVLDGTACSP-GAQGVCVAGRCLSAGCDGLL-GSGALEDRCGRCGGADD 188
Query: 389 --RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFAV 562
V +F GY V +P GA I V S N++AL + Y+LNG + V
Sbjct: 189 SCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRVEH--RSRNHLALMGGDGRYVLNGHWVV 246
Query: 563 SAPGMYEAAGAIFLYTRTAG-LDNVHANGPIYHPIDIMILYTHP 691
S PG YEAAG +YTR G + + A GP H + + +L P
Sbjct: 247 SPPGTYEAAGTHVVYTRDTGPQETLQAAGPTSHDLLLQVLLQEP 290
>AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 847
Score = 123 bits (297), Expect = 6e-28
Identities = 80/222 (36%), Positives = 108/222 (48%), Gaps = 11/222 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNA-PCALNC 223
K CLG RR+ CNT C G + R QCS FD PFRG+FY W Y G C+L C
Sbjct: 338 KYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTC 397
Query: 224 RPMGQQFYA-TLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC------ 382
G FY + V DGTPC D + ICV G CK +G + VL GS+ RE +C
Sbjct: 398 LAEGFNFYTERAAAVVDGTPCRPDTVD-ICVSGECKHVGCDRVL-GSDLREDKCRVCGGD 455
Query: 383 --GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEF 556
+ G+FS GY V +P+G+ I + +L S +++AL+ S +L G
Sbjct: 456 GSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLP 515
Query: 557 AVSAPGMYEAAGAIF-LYTRTAGLDNVHANGPIYHPIDIMIL 679
P AG F L + ++ A GPI + +M+L
Sbjct: 516 GTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVL 557
>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disintegrin
16 with thrombospondin type I motif protein.
Length = 1072
Score = 123 bits (296), Expect = 8e-28
Identities = 78/224 (34%), Positives = 117/224 (52%), Gaps = 12/224 (5%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALN 220
K C G R CN+Q C ++ RA QC+ + R FRGR Y W PY V+ C L
Sbjct: 623 KFCEGSTRTLKLCNSQKCPRDSVDFRAAQCAEHNSRRFRGRHYKWKPYTQVEDQDLCKLY 682
Query: 221 CRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR--- 388
C G F+ +LS V DGTPC++D +C+ G C+ +G ++VL GS++ E CG
Sbjct: 683 CIAEGFDFFFSLSNKVKDGTPCSEDSRN-VCIDGICERVGCDNVL-GSDAVEDVCGVCNG 740
Query: 389 -----RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGE 553
+ GL++K Y + T+P GA I + E+ S +YI++R + Y LNG
Sbjct: 741 NNSACTIHRGLYTKHHHTNQYYHMVTIPSGARSIRIYEMNVSTSYISVRNALRRYYLNGH 800
Query: 554 FAVSAPGMYEAAGAIFLYTRTAG-LDNVHANGPIYHPIDIMILY 682
+ V PG Y+ +G F Y R+ +N+ A GP + + +L+
Sbjct: 801 WTVDWPGRYKFSGTTFDYRRSYNEPENLIATGPTNETLIVELLF 844
>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
Length = 1021
Score = 123 bits (296), Expect = 8e-28
Identities = 78/224 (34%), Positives = 117/224 (52%), Gaps = 12/224 (5%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALN 220
K C G R CN+Q C ++ RA QC+ + R FRGR Y W PY V+ C L
Sbjct: 420 KFCEGSTRTLKLCNSQKCPRDSVDFRAAQCAEHNSRRFRGRHYKWKPYTQVEDQDLCKLY 479
Query: 221 CRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR--- 388
C G F+ +LS V DGTPC++D +C+ G C+ +G ++VL GS++ E CG
Sbjct: 480 CIAEGFDFFFSLSNKVKDGTPCSEDSRN-VCIDGICERVGCDNVL-GSDAVEDVCGVCNG 537
Query: 389 -----RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGE 553
+ GL++K Y + T+P GA I + E+ S +YI++R + Y LNG
Sbjct: 538 NNSACTIHRGLYTKHHHTNQYYHMVTIPSGARSIRIYEMNVSTSYISVRNALRRYYLNGH 597
Query: 554 FAVSAPGMYEAAGAIFLYTRTAG-LDNVHANGPIYHPIDIMILY 682
+ V PG Y+ +G F Y R+ +N+ A GP + + +L+
Sbjct: 598 WTVDWPGRYKFSGTTFDYRRSYNEPENLIATGPTNETLIVELLF 641
>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
protein.
Length = 1077
Score = 119 bits (287), Expect = 9e-27
Identities = 79/222 (35%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNA-PCALNC 223
K CLG RR+ CNT C G + R QCS FD PFRG+FY W Y G C+L
Sbjct: 558 KYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTS 617
Query: 224 RPMGQQFYA-TLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC------ 382
G FY + V DGTPC D + ICV G CK +G + VL GS+ RE +C
Sbjct: 618 LAEGFNFYTERAAAVVDGTPCRPDTVD-ICVSGECKHVGCDRVL-GSDLREDKCRVCGGD 675
Query: 383 --GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEF 556
+ G+FS GY V +P+G+ I + +L S +++AL+ S +L G
Sbjct: 676 GSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLP 735
Query: 557 AVSAPGMYEAAGAIF-LYTRTAGLDNVHANGPIYHPIDIMIL 679
P AG F L + ++ A GPI + +M+L
Sbjct: 736 GTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVL 777
>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 18 protein.
Length = 1221
Score = 118 bits (284), Expect = 2e-26
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 12/221 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C G R Y CN PC L+ RA+QC+ ++ +PFRG FY W PY V+ C L C+
Sbjct: 628 CPGSSRIYQLCNINPCNENSLDFRAQQCAEYNSKPFRGWFYQWKPYTKVEEEDRCKLYCK 687
Query: 227 PMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG------ 385
+F+ +S V DGTPC+ + +C+ G C+++G + L GS + CG
Sbjct: 688 AENFEFFFAMSGKVKDGTPCSPN-KNDVCIDGVCELVGCDHEL-GSKAVSDACGVCKGDN 745
Query: 386 --RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
+ GL+ Y V +P GA I + EL S +Y+A+R + Y L G ++
Sbjct: 746 STCKFYKGLYLNQHKANEYYPVVIIPAGARSIEIQELQVSSSYLAVRSLSQKYYLTGGWS 805
Query: 560 VSAPGMYEAAGAIFLYTRTAGL-DNVHANGPIYHPIDIMIL 679
+ PG + AG F Y R+ + ++A GP + IL
Sbjct: 806 IDWPGEFPFAGTTFEYQRSFNRPERLYAPGPTNETLVFEIL 846
>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
Length = 1081
Score = 118 bits (284), Expect = 2e-26
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 12/221 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPY--VDGNAPCALNCR 226
C G R Y CN PC L+ RA+QC+ ++ +PFRG FY W PY V+ C L C+
Sbjct: 627 CPGSSRIYQLCNINPCNENSLDFRAQQCAEYNSKPFRGWFYQWKPYTKVEEEDRCKLYCK 686
Query: 227 PMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG------ 385
+F+ +S V DGTPC+ + +C+ G C+++G + L GS + CG
Sbjct: 687 AENFEFFFAMSGKVKDGTPCSPN-KNDVCIDGVCELVGCDHEL-GSKAVSDACGVCKGDN 744
Query: 386 --RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFA 559
+ GL+ Y V +P GA I + EL S +Y+A+R + Y L G ++
Sbjct: 745 STCKFYKGLYLNQHKANEYYPVVLIPAGARSIEIQELQVSSSYLAVRSLSQKYYLTGGWS 804
Query: 560 VSAPGMYEAAGAIFLYTRTAGL-DNVHANGPIYHPIDIMIL 679
+ PG + AG F Y R+ + ++A GP + IL
Sbjct: 805 IDWPGEFPFAGTTFEYQRSFNRPERLYAPGPTNETLVFEIL 845
>BC109114-1|AAI09115.1| 950|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 15 protein.
Length = 950
Score = 107 bits (258), Expect = 3e-23
Identities = 80/236 (33%), Positives = 113/236 (47%), Gaps = 25/236 (10%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNT--RAEQCSSFDRRPFRGRFYT----WIPYVDGNAP 208
K C GV +Y CN +PC R EQC +F+ T W+P G +P
Sbjct: 553 KYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSP 612
Query: 209 ---CALNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSREL 376
C L CR G FY V DGT C+ D ++CVQG C G + L GS R
Sbjct: 613 RDKCKLICRANGTGYFYVLAPKVVDGTLCSPDST-SVCVQGKCIKAGCDGNL-GSKKRFD 670
Query: 377 RCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTE-----LASSENYIAL 517
+CG + V+GLF+KP GY FV +P GA I++ + L +NY+AL
Sbjct: 671 KCGVCGGDNKSCKKVTGLFTKPMH--GYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLAL 728
Query: 518 RLSNSSYILNGEFAVSAPGM-YEAAGAIFLYTRT-AGLDNVHANGPIYHPIDIMIL 679
+ S Y+LNG F VSA G++ Y+ T ++++ A+ PI P+ + +L
Sbjct: 729 KNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTVEVL 784
>AJ315733-1|CAC86014.1| 950|Homo sapiens metalloprotease disintegrin
15 with thrombospondin domains protein.
Length = 950
Score = 107 bits (258), Expect = 3e-23
Identities = 80/236 (33%), Positives = 113/236 (47%), Gaps = 25/236 (10%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNT--RAEQCSSFDRRPFRGRFYT----WIPYVDGNAP 208
K C GV +Y CN +PC R EQC +F+ T W+P G +P
Sbjct: 553 KYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSP 612
Query: 209 ---CALNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSREL 376
C L CR G FY V DGT C+ D ++CVQG C G + L GS R
Sbjct: 613 RDKCKLICRANGTGYFYVLAPKVVDGTLCSPDST-SVCVQGKCIKAGCDGNL-GSKKRFD 670
Query: 377 RCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTE-----LASSENYIAL 517
+CG + V+GLF+KP GY FV +P GA I++ + L +NY+AL
Sbjct: 671 KCGVCGGDNKSCKKVTGLFTKPMH--GYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLAL 728
Query: 518 RLSNSSYILNGEFAVSAPGM-YEAAGAIFLYTRT-AGLDNVHANGPIYHPIDIMIL 679
+ S Y+LNG F VSA G++ Y+ T ++++ A+ PI P+ + +L
Sbjct: 729 KNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTVEVL 784
>BX649571-2|CAI18773.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 87 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 146
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 147 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 204
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 205 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 264
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 265 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 314
>BX649571-1|CAM26559.1| 1060|Homo sapiens ADAMTS-like 2 protein.
Length = 1060
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 196 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 255
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 256 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 313
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 314 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 373
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 374 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 423
>BX629352-2|CAI23592.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 87 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 146
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 147 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 204
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 205 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 264
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 265 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 314
>BX629352-1|CAM28356.1| 1060|Homo sapiens ADAMTS-like 2 protein.
Length = 1060
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 196 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 255
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 256 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 313
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 314 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 373
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 374 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 423
>BX324209-2|CAI17317.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 87 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 146
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 147 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 204
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 205 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 264
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 265 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 314
>BX324209-1|CAM24586.1| 1060|Homo sapiens ADAMTS-like 2 protein.
Length = 1060
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 196 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 255
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 256 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 313
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 314 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 373
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 374 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 423
>BC050544-1|AAH50544.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 87 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 146
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 147 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 204
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 205 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 264
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 265 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 314
>AB011177-1|BAA25531.2| 1031|Homo sapiens KIAA0605 protein protein.
Length = 1031
Score = 107 bits (257), Expect = 4e-23
Identities = 69/230 (30%), Positives = 105/230 (45%), Gaps = 19/230 (8%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVD-----GNA 205
N+ C G +RY C Q C + R EQC SF+ + GR + W P Y D +
Sbjct: 167 NRTCTGTSKRYQLCRVQECPPDGRSFREEQCVSFNSHVYNGRTHQWKPLYPDDYVHISSK 226
Query: 206 PCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
PC L+C + Q + DGT C L +CV G C+ IG + VL +++ + +CG
Sbjct: 227 PCDLHCTTVDGQRQLMVP-ARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLD-KCG 284
Query: 386 R--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
V+G + K LGY+ V +P GA I + E S + +AL Y
Sbjct: 285 ICQGDGSSCTHVTGNYRKGNAHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGYYF 344
Query: 542 LNGEFAVSAPGMYEAAGAIFLYTR-----TAGLDNVHANGPIYHPIDIMI 676
NG + V +P + AG + Y R G++ + A GP +++M+
Sbjct: 345 FNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMV 394
>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
Length = 1207
Score = 106 bits (255), Expect = 7e-23
Identities = 70/221 (31%), Positives = 105/221 (47%), Gaps = 10/221 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGR-FYTWIPYVDGNAPCALNC 223
+ C G ++Y C PC G+ R QC ++ R + W +D PCAL C
Sbjct: 668 RDCNGPRKQYRICENPPCPAGLPGFRDWQCQAYSVRTSSPKHILQWQAVLDEEKPCALFC 727
Query: 224 RPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR---- 388
P+G++ LS V DGT C GL IC G C+ +G + +L GS +RE CG
Sbjct: 728 SPVGKEQPILLSEKVMDGTSCGYQGLD-ICANGRCQKVGCDGLL-GSLAREDHCGVCNGN 785
Query: 389 ----RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEF 556
+++ G F+ R GY V +P GA RI V E + +Y+ALR + I N ++
Sbjct: 786 GKSCKIIKGDFNHTR-GAGYVEVLVIPAGARRIKVVEEKPAHSYLALRDAGKQSI-NSDW 843
Query: 557 AVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ G + AG Y R + + A GP P+ +++L
Sbjct: 844 KIEHSGAFNLAGTTVHYVRRGLWEKISAKGPTTAPLHLLVL 884
>BC063293-1|AAH63293.1| 837|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 837
Score = 105 bits (252), Expect = 2e-22
Identities = 82/241 (34%), Positives = 118/241 (48%), Gaps = 24/241 (9%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPC-AGGVLNTRAEQCSSFDRR-----PFRGRFYTWIPY 190
VTR K C G R+ CNT+ C G L R EQC++++ R F G W+P
Sbjct: 551 VTRNGGKYCEGRRARFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPM-DWVPR 609
Query: 191 VDGNAP---CALNCRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAG 358
G AP C L C+ +Y L V DGTPC+ D ++CVQG C G + ++ G
Sbjct: 610 YTGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDS-SSVCVQGRCIHAGCDRII-G 667
Query: 359 SNSRELRC--------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN--- 505
S + +C G SG F K R GY V T+P GA I V + + +
Sbjct: 668 SKKKFDKCMVCGGDGSGCSKQSGSFRKFR--YGYNNVVTIPAGATHILVRQQGNPGHRSI 725
Query: 506 YIALRLSNSSYILNGEFA-VSAPGMYEAAGAIFL-YT-RTAGLDNVHANGPIYHPIDIMI 676
Y+AL+L + SY LNGE+ + +P GA+ L Y+ TA + + +GP+ P+ + +
Sbjct: 726 YLALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQV 785
Query: 677 L 679
L
Sbjct: 786 L 786
>AY044847-1|AAL02262.1| 837|Homo sapiens aggrecanase 1 protein.
Length = 837
Score = 103 bits (246), Expect = 9e-22
Identities = 79/240 (32%), Positives = 117/240 (48%), Gaps = 23/240 (9%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPC-AGGVLNTRAEQCSSFDRRPFRGRFYT----WIPYV 193
V R K C G R+ CNT+ C G L R EQC++++ R + + W+P
Sbjct: 551 VPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRY 610
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G AP C L C+ +Y L V DGTPC+ D ++CVQG C G + ++ GS
Sbjct: 611 TGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDS-SSVCVQGRCIHAGCDRII-GS 668
Query: 362 NSRELRC--------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN---Y 508
+ +C G SG F K R GY V T+P GA I V + + + Y
Sbjct: 669 KKKFDKCMVCGGDRSGCSKQSGSFRKFRY--GYNNVVTIPAGATHILVRQQGNPGHRSIY 726
Query: 509 IALRLSNSSYILNGEFA-VSAPGMYEAAGAIFL-YT-RTAGLDNVHANGPIYHPIDIMIL 679
+AL+L + SY LNGE+ + +P GA+ L Y+ TA + + +GP+ P+ + +L
Sbjct: 727 LALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVL 786
>AL590714-6|CAH72146.1| 837|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 837
Score = 103 bits (246), Expect = 9e-22
Identities = 79/240 (32%), Positives = 117/240 (48%), Gaps = 23/240 (9%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPC-AGGVLNTRAEQCSSFDRRPFRGRFYT----WIPYV 193
V R K C G R+ CNT+ C G L R EQC++++ R + + W+P
Sbjct: 551 VPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRY 610
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G AP C L C+ +Y L V DGTPC+ D ++CVQG C G + ++ GS
Sbjct: 611 TGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDS-SSVCVQGRCIHAGCDRII-GS 668
Query: 362 NSRELRC--------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN---Y 508
+ +C G SG F K R GY V T+P GA I V + + + Y
Sbjct: 669 KKKFDKCMVCGGDGSGCSKQSGSFRKFRY--GYNNVVTIPAGATHILVRQQGNPGHRSIY 726
Query: 509 IALRLSNSSYILNGEFA-VSAPGMYEAAGAIFL-YT-RTAGLDNVHANGPIYHPIDIMIL 679
+AL+L + SY LNGE+ + +P GA+ L Y+ TA + + +GP+ P+ + +L
Sbjct: 727 LALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVL 786
>AY358886-1|AAQ89245.1| 837|Homo sapiens ADAMTS4 protein.
Length = 837
Score = 102 bits (245), Expect = 1e-21
Identities = 79/240 (32%), Positives = 117/240 (48%), Gaps = 23/240 (9%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPC-AGGVLNTRAEQCSSFDRRPFRGRFYT----WIPYV 193
V R K C G R+ CNT+ C G L R EQC++++ R + + W+P
Sbjct: 551 VPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRY 610
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G AP C L C+ +Y L V DGTPC+ D ++CVQG C G + ++ GS
Sbjct: 611 TGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDS-SSVCVQGRCIHAGCDRII-GS 668
Query: 362 NSRELRC--------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN---Y 508
+ +C G SG F K R GY V T+P GA I V + + + Y
Sbjct: 669 KKKFDKCMVCGGDGSGCSKQSGSFRKFRY--GYNNVVTIPAGATHILVRQQGNPGHRSIY 726
Query: 509 IALRLSNSSYILNGEFA-VSAPGMYEAAGAIFL-YT-RTAGLDNVHANGPIYHPIDIMIL 679
+AL+L + SY LNGE+ + +P GA+ L Y+ TA + + +GP+ P+ + +L
Sbjct: 727 LALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVL 786
>AF148213-1|AAD41494.1| 837|Homo sapiens aggrecanase-1 protein.
Length = 837
Score = 102 bits (245), Expect = 1e-21
Identities = 79/240 (32%), Positives = 117/240 (48%), Gaps = 23/240 (9%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPC-AGGVLNTRAEQCSSFDRRPFRGRFYT----WIPYV 193
V R K C G R+ CNT+ C G L R EQC++++ R + + W+P
Sbjct: 551 VPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRY 610
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G AP C L C+ +Y L V DGTPC+ D ++CVQG C G + ++ GS
Sbjct: 611 TGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDS-SSVCVQGRCIHAGCDRII-GS 668
Query: 362 NSRELRC--------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN---Y 508
+ +C G SG F K R GY V T+P GA I V + + + Y
Sbjct: 669 KKKFDKCMVCGGDGSGCSKQSGSFRKFRY--GYNNVVTIPAGATHILVRQQGNPGHRSIY 726
Query: 509 IALRLSNSSYILNGEFA-VSAPGMYEAAGAIFL-YT-RTAGLDNVHANGPIYHPIDIMIL 679
+AL+L + SY LNGE+ + +P GA+ L Y+ TA + + +GP+ P+ + +L
Sbjct: 727 LALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVL 786
>AB014588-1|BAA31663.2| 849|Homo sapiens KIAA0688 protein protein.
Length = 849
Score = 102 bits (245), Expect = 1e-21
Identities = 79/240 (32%), Positives = 117/240 (48%), Gaps = 23/240 (9%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPC-AGGVLNTRAEQCSSFDRRPFRGRFYT----WIPYV 193
V R K C G R+ CNT+ C G L R EQC++++ R + + W+P
Sbjct: 563 VPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRY 622
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G AP C L C+ +Y L V DGTPC+ D ++CVQG C G + ++ GS
Sbjct: 623 TGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDS-SSVCVQGRCIHAGCDRII-GS 680
Query: 362 NSRELRC--------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN---Y 508
+ +C G SG F K R GY V T+P GA I V + + + Y
Sbjct: 681 KKKFDKCMVCGGDGSGCSKQSGSFRKFRY--GYNNVVTIPAGATHILVRQQGNPGHRSIY 738
Query: 509 IALRLSNSSYILNGEFA-VSAPGMYEAAGAIFL-YT-RTAGLDNVHANGPIYHPIDIMIL 679
+AL+L + SY LNGE+ + +P GA+ L Y+ TA + + +GP+ P+ + +L
Sbjct: 739 LALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVL 798
>BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein.
Length = 1691
Score = 94.7 bits (225), Expect = 3e-19
Identities = 66/224 (29%), Positives = 100/224 (44%), Gaps = 11/224 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVDGNAPCALNC 223
+ C G + RY C+ C + RA+QCS+++ ++GR+Y W+P Y D APCAL C
Sbjct: 106 RNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYNDVQYQGRYYEWLPRYNDPAAPCALKC 165
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
GQ L+ V DGT C D L +C+ G C+ +G + L GSN++E CG
Sbjct: 166 HAQGQNLVVELAPKVLDGTRCNTDSLD-MCISGICQAVGCDRQL-GSNAKEDNCGVCAGD 223
Query: 386 ---RRLVSGLFSKPRLP-LGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGE 553
RLV G P V VP G+ + +T + +I + S GE
Sbjct: 224 GSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRITVKGPAHLFIESKTLQGS---KGE 280
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMILYT 685
+ ++PG++ + R + GP+ YT
Sbjct: 281 HSFNSPGVFVVENTTVEFQRGSERQTFKIPGPLMADFIFKTRYT 324
>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
Length = 1205
Score = 93.5 bits (222), Expect = 7e-19
Identities = 65/228 (28%), Positives = 111/228 (48%), Gaps = 15/228 (6%)
Frame = +2
Query: 41 INKG--CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRR-PFRGRFYTWIPYV--DGNA 205
IN G C GV+ Y CNT+ C + RA+QC + ++ + W+PY D
Sbjct: 584 INGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNTKHHWLPYEHPDPKK 643
Query: 206 PCALNCRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L C+ A + +V DGT C+ +ICV+G C +G + + GSN E +C
Sbjct: 644 RCHLYCQSKETGDVAYMKQLVHDGTHCSYKDPYSICVRGECVKVGCDKEI-GSNKVEDKC 702
Query: 383 GR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALR-LSNSS 535
G R V G F++ LGY + +P GA + + E +S + +A++ +
Sbjct: 703 GVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGH 762
Query: 536 YILNGEFAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
YILNG+ + + G + Y ++++H +GP++ P+ ++I+
Sbjct: 763 YILNGKGEEAKSRTFIDLGVEWDYNIEDDIESLHTDGPLHDPVIVLII 810
>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 3 protein.
Length = 1205
Score = 93.5 bits (222), Expect = 7e-19
Identities = 65/228 (28%), Positives = 111/228 (48%), Gaps = 15/228 (6%)
Frame = +2
Query: 41 INKG--CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRR-PFRGRFYTWIPYV--DGNA 205
IN G C GV+ Y CNT+ C + RA+QC + ++ + W+PY D
Sbjct: 584 INGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNTKHHWLPYEHPDPKK 643
Query: 206 PCALNCRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L C+ A + +V DGT C+ +ICV+G C +G + + GSN E +C
Sbjct: 644 RCHLYCQSKETGDVAYMKQLVHDGTHCSYKDPYSICVRGECVKVGCDKEI-GSNKVEDKC 702
Query: 383 GR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALR-LSNSS 535
G R V G F++ LGY + +P GA + + E +S + +A++ +
Sbjct: 703 GVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGH 762
Query: 536 YILNGEFAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
YILNG+ + + G + Y ++++H +GP++ P+ ++I+
Sbjct: 763 YILNGKGEEAKSRTFIDLGVEWDYNIEDDIESLHTDGPLHDPVIVLII 810
>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
Length = 1201
Score = 93.5 bits (222), Expect = 7e-19
Identities = 65/228 (28%), Positives = 111/228 (48%), Gaps = 15/228 (6%)
Frame = +2
Query: 41 INKG--CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRR-PFRGRFYTWIPYV--DGNA 205
IN G C GV+ Y CNT+ C + RA+QC + ++ + W+PY D
Sbjct: 580 INGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNTKHHWLPYEHPDPKK 639
Query: 206 PCALNCRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L C+ A + +V DGT C+ +ICV+G C +G + + GSN E +C
Sbjct: 640 RCHLYCQSKETGDVAYMKQLVHDGTHCSYKDPYSICVRGECVKVGCDKEI-GSNKVEDKC 698
Query: 383 GR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALR-LSNSS 535
G R V G F++ LGY + +P GA + + E +S + +A++ +
Sbjct: 699 GVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGH 758
Query: 536 YILNGEFAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
YILNG+ + + G + Y ++++H +GP++ P+ ++I+
Sbjct: 759 YILNGKGEEAKSRTFIDLGVEWDYNIEDDIESLHTDGPLHDPVIVLII 806
>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 9 protein.
Length = 1935
Score = 93.1 bits (221), Expect = 9e-19
Identities = 68/194 (35%), Positives = 94/194 (48%), Gaps = 21/194 (10%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPF--RGRF--YTWIPYVDG---NA 205
K C+G ++ CNT+PC + R EQC+ FD + F G W+P G
Sbjct: 625 KYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKD 684
Query: 206 PCALNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L CR G +Y V DGTPC QD ICVQG C+ G + VL S +R +C
Sbjct: 685 RCKLFCRVAGNTAYYQLRDRVIDGTPCGQD-TNDICVQGLCRQAGCDHVL-NSKARRDKC 742
Query: 383 G--------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS-----ENYIALRL 523
G + V+G F+ + GY V +P GA I+V + + S +NY+AL
Sbjct: 743 GVCGGDNSSCKTVAGTFN--TVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSS 800
Query: 524 SNSSYILNGEFAVS 565
S ++LNG F V+
Sbjct: 801 SKGEFLLNGNFVVT 814
>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 9B
protein.
Length = 1935
Score = 93.1 bits (221), Expect = 9e-19
Identities = 68/194 (35%), Positives = 94/194 (48%), Gaps = 21/194 (10%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPF--RGRF--YTWIPYVDG---NA 205
K C+G ++ CNT+PC + R EQC+ FD + F G W+P G
Sbjct: 625 KYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKD 684
Query: 206 PCALNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L CR G +Y V DGTPC QD ICVQG C+ G + VL S +R +C
Sbjct: 685 RCKLFCRVAGNTAYYQLRDRVIDGTPCGQD-TNDICVQGLCRQAGCDHVL-NSKARRDKC 742
Query: 383 G--------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS-----ENYIALRL 523
G + V+G F+ + GY V +P GA I+V + + S +NY+AL
Sbjct: 743 GVCGGDNSSCKTVAGTFN--TVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSS 800
Query: 524 SNSSYILNGEFAVS 565
S ++LNG F V+
Sbjct: 801 SKGEFLLNGNFVVT 814
>AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin
metalloproteinase with thrombospondin repeats protein.
Length = 1072
Score = 93.1 bits (221), Expect = 9e-19
Identities = 68/194 (35%), Positives = 94/194 (48%), Gaps = 21/194 (10%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPF--RGRF--YTWIPYVDG---NA 205
K C+G ++ CNT+PC + R EQC+ FD + F G W+P G
Sbjct: 625 KYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKD 684
Query: 206 PCALNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L CR G +Y V DGTPC QD ICVQG C+ G + VL S +R +C
Sbjct: 685 RCKLFCRVAGNTAYYQLRDRVIDGTPCGQD-TNDICVQGLCRQAGCDHVL-NSKARRDKC 742
Query: 383 G--------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS-----ENYIALRL 523
G + V+G F+ + GY V +P GA I+V + + S +NY+AL
Sbjct: 743 GVCGGDNSSCKTVAGTFN--TVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSS 800
Query: 524 SNSSYILNGEFAVS 565
S ++LNG F V+
Sbjct: 801 SKGEFLLNGNFVVT 814
>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
Length = 1471
Score = 93.1 bits (221), Expect = 9e-19
Identities = 68/194 (35%), Positives = 94/194 (48%), Gaps = 21/194 (10%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPF--RGRF--YTWIPYVDG---NA 205
K C+G ++ CNT+PC + R EQC+ FD + F G W+P G
Sbjct: 467 KYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKD 526
Query: 206 PCALNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC 382
C L CR G +Y V DGTPC QD ICVQG C+ G + VL S +R +C
Sbjct: 527 RCKLFCRVAGNTAYYQLRDRVIDGTPCGQD-TNDICVQGLCRQAGCDHVL-NSKARRDKC 584
Query: 383 G--------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS-----ENYIALRL 523
G + V+G F+ + GY V +P GA I+V + + S +NY+AL
Sbjct: 585 GVCGGDNSSCKTVAGTFN--TVHYGYNTVVRIPAGATNIDVRQHSFSGETDDDNYLALSS 642
Query: 524 SNSSYILNGEFAVS 565
S ++LNG F V+
Sbjct: 643 SKGEFLLNGNFVVT 656
>BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein.
Length = 1682
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/224 (29%), Positives = 99/224 (44%), Gaps = 11/224 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVDGNAPCALNC 223
+ C G + RY C+ C + RA+QCS+++ ++G +Y W+P Y D APCAL C
Sbjct: 106 RNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYNDVQYQGHYYEWLPRYNDPAAPCALKC 165
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
GQ L+ V DGT C D L +C+ G C+ +G + L GSN++E CG
Sbjct: 166 HAQGQNLVVELAPKVLDGTRCNTDSLD-MCISGICQAVGCDRQL-GSNAKEDNCGVCAGD 223
Query: 386 ---RRLVSGLFSKPRLP-LGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGE 553
RLV G P V VP G+ + +T + +I + S GE
Sbjct: 224 GSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRITVKGPAHLFIESKTLQGS---KGE 280
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMILYT 685
+ ++PG++ + R + GP+ YT
Sbjct: 281 HSFNSPGVFVVENTTVEFQRGSERQTFKIPGPLMADFIFKTRYT 324
>AF237652-1|AAK15041.1| 766|Homo sapiens a disintegrin-like and
metalloprotease domain with thrombospondin type I motifs
protein.
Length = 766
Score = 91.5 bits (217), Expect = 3e-18
Identities = 65/224 (29%), Positives = 98/224 (43%), Gaps = 11/224 (4%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVDGNAPCALNC 223
+ C G + RY C+ C + RA+QCS+++ ++G +Y W+P Y D APCAL C
Sbjct: 106 RNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYNDVQYQGHYYEWLPRYNDPAAPCALKC 165
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
GQ L+ V DGT C D L +C+ G C+ +G + L GSN++E CG
Sbjct: 166 HAQGQNLVVELAPKVLDGTRCNTDSLD-MCISGICQAVGCDRQL-GSNAKEDNCGVCAGD 223
Query: 386 ---RRLVSGLFSKPRLP-LGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGE 553
RLV G P V VP G+ + +T +I + S GE
Sbjct: 224 GSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRITVKGPVHLFIESKTLQGS---KGE 280
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMILYT 685
+ ++PG++ + R + GP+ YT
Sbjct: 281 HSFNSPGVFVVENTTVEFQRGSERQTFKIPGPLMADFIFKTRYT 324
>AK092324-1|BAC03862.1| 296|Homo sapiens protein ( Homo sapiens
cDNA FLJ35005 fis, clone OCBBF2012001, weakly similar to
Homo sapiens zinc metalloprotease ADAMTS6 (ADAMTS6)
mRNA. ).
Length = 296
Score = 88.6 bits (210), Expect = 2e-17
Identities = 44/115 (38%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP-YVDGNAPCALNC 223
+ C G + RY C+ C + RA+QCS+++ ++G +Y W+P Y D APCAL C
Sbjct: 106 RNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYNDVQYQGHYYEWLPRYNDPAAPCALKC 165
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
GQ L+ V DGT C D L +C+ G C+ +G + L GSN++E CG
Sbjct: 166 HAQGQNLVVELAPKVLDGTRCNTDSLD-MCISGICQAVGCDRQL-GSNAKEDNCG 218
>BC113874-1|AAI13875.1| 676|Homo sapiens ADAMTS8 protein protein.
Length = 676
Score = 87.8 bits (208), Expect = 4e-17
Identities = 68/230 (29%), Positives = 110/230 (47%), Gaps = 21/230 (9%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR---GRFYTWIPYVDGNAP---CA 214
CLG +Y C+T+ C + R +QC ++ + G W+P G +P C
Sbjct: 352 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 411
Query: 215 LNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRE---LRC 382
L CR G+ +F + V DGT C + L AICV+G C G + V+ + +R
Sbjct: 412 LFCRARGRSEFKVFEAKVIDGTLCGPETL-AICVRGQCVKAGCDHVVDSPRKLDKCGVRG 470
Query: 383 GR----RLVSGLFSKPRLPLGYTFVATVPRGACRINVTE-----LASSENYIALRLSNSS 535
G+ R VSG + GY + T+P GA I+V + + + NY+AL+ ++
Sbjct: 471 GKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADGQ 528
Query: 536 YILNGEFAVSAPGM-YEAAGAIFLYTRT-AGLDNVHANGPIYHPIDIMIL 679
Y+LNG A+SA G I Y+ + A L+ + + P+ P+ + +L
Sbjct: 529 YLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLL 578
>BC089435-1|AAH89435.1| 918|Homo sapiens ADAMTS8 protein protein.
Length = 918
Score = 87.4 bits (207), Expect = 5e-17
Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 22/231 (9%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR---GRFYTWIPYVDGNAP---CA 214
CLG +Y C+T+ C + R +QC ++ + G W+P G +P C
Sbjct: 594 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 653
Query: 215 LNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR- 388
L CR G+ +F + V DGT C + L AICV+G C G + V+ + +CG
Sbjct: 654 LFCRARGRSEFKVFEAKVIDGTLCGPETL-AICVRGQCVKAGCDHVVDSPRKLD-KCGVC 711
Query: 389 -------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTE-----LASSENYIALRLSNS 532
R VSG + GY + T+P GA I+V + + + NY+AL+ ++
Sbjct: 712 GGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADG 769
Query: 533 SYILNGEFAVSAPGM-YEAAGAIFLYTRT-AGLDNVHANGPIYHPIDIMIL 679
Y+LNG A+SA G I Y+ + A L+ + + P+ P+ + +L
Sbjct: 770 QYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLL 820
>AF060153-1|AAD48081.1| 890|Homo sapiens METH2 protein protein.
Length = 890
Score = 87.4 bits (207), Expect = 5e-17
Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 22/231 (9%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR---GRFYTWIPYVDGNAP---CA 214
CLG +Y C+T+ C + R +QC ++ + G W+P G +P C
Sbjct: 566 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 625
Query: 215 LNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR- 388
L CR G+ +F + V DGT C + L AICV+G C G + V+ + +CG
Sbjct: 626 LFCRARGRSEFKVFEAKVIDGTLCGPETL-AICVRGQCVKAGCDHVVDSPRKLD-KCGVC 683
Query: 389 -------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTE-----LASSENYIALRLSNS 532
R VSG + GY + T+P GA I+V + + + NY+AL+ ++
Sbjct: 684 GGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADG 741
Query: 533 SYILNGEFAVSAPGM-YEAAGAIFLYTRT-AGLDNVHANGPIYHPIDIMIL 679
Y+LNG A+SA G I Y+ + A L+ + + P+ P+ + +L
Sbjct: 742 QYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLL 792
>AB209717-1|BAD92954.1| 418|Homo sapiens ADAMTS-8 precursor variant
protein.
Length = 418
Score = 87.4 bits (207), Expect = 5e-17
Identities = 68/231 (29%), Positives = 109/231 (47%), Gaps = 22/231 (9%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR---GRFYTWIPYVDGNAP---CA 214
CLG +Y C+T+ C + R +QC ++ + G W+P G +P C
Sbjct: 94 CLGRRAKYQSCHTEECPPDGKSFREQQCEKYNAYNYTDMDGNLLQWVPKYAGVSPRDRCK 153
Query: 215 LNCRPMGQ-QFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGR- 388
L CR G+ +F + V DGT C + L AICV+G C G + V+ + +CG
Sbjct: 154 LFCRARGRSEFKVFEAKVIDGTLCGPETL-AICVRGQCVKAGCDHVVDSPRKLD-KCGVC 211
Query: 389 -------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTE-----LASSENYIALRLSNS 532
R VSG + GY + T+P GA I+V + + + NY+AL+ ++
Sbjct: 212 GGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATNIDVKQRSHPGVQNDGNYLALKTADG 269
Query: 533 SYILNGEFAVSAPGM-YEAAGAIFLYTRT-AGLDNVHANGPIYHPIDIMIL 679
Y+LNG A+SA G I Y+ + A L+ + + P+ P+ + +L
Sbjct: 270 QYLLNGNLAISAIEQDILVKGTILKYSGSIATLERLQSFRPLPEPLTVQLL 320
>BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 1 protein.
Length = 967
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 590 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 649
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 650 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSTDST-SVCVQGQCVKAGCDRII-DS 707
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 708 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 765
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 766 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 823
Query: 671 MIL 679
+L
Sbjct: 824 QVL 826
>AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with
thrombospondin type 1 motifs protein.
Length = 967
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 590 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 649
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 650 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDST-SVCVQGQCVKAGCDRII-DS 707
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 708 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 765
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 766 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 823
Query: 671 MIL 679
+L
Sbjct: 824 QVL 826
>AL162080-1|CAB82413.1| 550|Homo sapiens hypothetical protein
protein.
Length = 550
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 173 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 232
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 233 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDST-SVCVQGQCVKAGCDRII-DS 290
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 291 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 348
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 349 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 406
Query: 671 MIL 679
+L
Sbjct: 407 QVL 409
>AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease
protein.
Length = 967
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 590 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 649
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 650 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDST-SVCVQGQCVKAGCDRII-DS 707
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 708 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 765
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 766 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 823
Query: 671 MIL 679
+L
Sbjct: 824 QVL 826
>AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with
thrombospondin type 1 motifs ADAMTS1 protein.
Length = 967
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 590 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 649
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 650 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDST-SVCVQGQCVKAGCDRII-DS 707
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 708 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 765
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 766 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 823
Query: 671 MIL 679
+L
Sbjct: 824 QVL 826
>AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein.
Length = 950
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 573 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 632
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 633 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDST-SVCVQGQCVKAGCDRII-DS 690
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 691 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 748
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 749 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 806
Query: 671 MIL 679
+L
Sbjct: 807 QVL 809
>AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein.
Length = 999
Score = 84.2 bits (199), Expect = 4e-16
Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 26/243 (10%)
Frame = +2
Query: 29 VTRQINKGCLGVDRRYHECNTQPCAGGVLNT-RAEQCSS---FDRRPF-RGRFYTWIPYV 193
V + K C G RY CN + C T R EQC + F + F G WIP
Sbjct: 622 VPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHNEFSKASFGSGPAVEWIPKY 681
Query: 194 DGNAP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGS 361
G +P C L C+ G ++ L V DGTPC+ D ++CVQG C G + ++ S
Sbjct: 682 AGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDST-SVCVQGQCVKAGCDRII-DS 739
Query: 362 NSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINV---TELASSEN- 505
+ +CG + +SG + + P GY + T+P GA I V + S N
Sbjct: 740 KKKFDKCGVCGGNGSTCKKISGSVTSAK-P-GYHDIITIPTGATNIEVKQRNQRGSRNNG 797
Query: 506 -YIALRLSNSSYILNGEFAVSA---PGMYEAAGAIFLYT-RTAGLDNVHANGPIYHPIDI 670
++A++ ++ +YILNG++ +S MY+ G + Y+ +A L+ + + P+ P+ I
Sbjct: 798 SFLAIKAADGTYILNGDYTLSTLEQDIMYK--GVVLRYSGSSAALERIRSFSPLKEPLTI 855
Query: 671 MIL 679
+L
Sbjct: 856 QVL 858
>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
protein.
Length = 1211
Score = 83.4 bits (197), Expect = 8e-16
Identities = 59/224 (26%), Positives = 109/224 (48%), Gaps = 15/224 (6%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRF-YTWIPYV--DGNAPCALNC 223
C G+ + C+ Q C + + R EQC +D G + W+P+ D C L C
Sbjct: 600 CSGLAYDFQLCSRQDCPDSLADFREEQCRQWDLYFEHGDAQHHWLPHEHRDAKERCHLYC 659
Query: 224 --RPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG---- 385
R G+ + +V DGT C+ ++CV+G C+ +G + V+ GS+ +E +CG
Sbjct: 660 ESRETGE-VVSMKRMVHDGTRCSYKDAFSLCVRGDCRKVGCDGVI-GSSKQEDKCGVCGG 717
Query: 386 ----RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALR-LSNSSYILNG 550
++V G F++ GY + +P GA + + E+ ++ +++A++ L +ILN
Sbjct: 718 DNSHCKVVKGTFTRSPKKHGYIKMFEIPAGARHLLIQEVDATSHHLAVKNLETGKFILNE 777
Query: 551 EFAVSAPG-MYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
E V A + A G + Y G + + GP++ I ++++
Sbjct: 778 ENDVDASSKTFIAMGVEWEYRDEDGRETLQTMGPLHGTITVLVI 821
>AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.
Length = 1908
Score = 81.0 bits (191), Expect = 4e-15
Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRR--PFRG--RFYTWIPYVDG---NAPC 211
C+G ++ CNT C G + R +QCS F+ + G W+P G C
Sbjct: 595 CVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGVGTKDRC 654
Query: 212 ALNCRPMG-QQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG- 385
L C+ G FY +V+DGTPC + ICVQG C G + VL S+++ +CG
Sbjct: 655 KLYCQVAGTNYFYLLKDMVEDGTPCGTE-THDICVQGQCMAAGCDHVL-NSSAKIDKCGV 712
Query: 386 -------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS----ENYIALRLSNS 532
+ ++G+F+ GY V +P GA +++ + + S ++Y+AL +
Sbjct: 713 CGGDNSSCKTITGVFNSSH--YGYNVVVKIPAGATNVDIRQYSYSGQPDDSYLALSDAEG 770
Query: 533 SYILNGEFAVS 565
+++ NG F +S
Sbjct: 771 NFLFNGNFLLS 781
>AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 20
protein.
Length = 1911
Score = 81.0 bits (191), Expect = 4e-15
Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRR--PFRG--RFYTWIPYVDG---NAPC 211
C+G ++ CNT C G + R +QCS F+ + G W+P G C
Sbjct: 595 CVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGIGTKDRC 654
Query: 212 ALNCRPMG-QQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG- 385
L C+ G FY +V+DGTPC + ICVQG C G + VL S+++ +CG
Sbjct: 655 KLYCQVAGTNYFYLLKDMVEDGTPCGTE-THDICVQGQCMAAGCDHVL-NSSAKIDKCGV 712
Query: 386 -------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS----ENYIALRLSNS 532
+ ++G+F+ GY V +P GA +++ + + S ++Y+AL +
Sbjct: 713 CGGDNSSCKTITGVFNSSH--YGYNVVVKIPAGATNVDIRQYSYSGQPDDSYLALSDAEG 770
Query: 533 SYILNGEFAVS 565
+++ NG F +S
Sbjct: 771 NFLFNGNFLLS 781
>AF141293-1|AAF02493.1| 518|Homo sapiens ADAMTS5 protein protein.
Length = 518
Score = 80.6 bits (190), Expect = 5e-15
Identities = 64/227 (28%), Positives = 103/227 (45%), Gaps = 23/227 (10%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFD--RRPFRG--RFYTWIPYVDGN 202
R + C G YH C+ PC + R EQC + + + +G F W+P G
Sbjct: 188 RNNGRYCTGKRAIYHSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGV 247
Query: 203 AP---CALNCRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSR 370
P C L CR G +Y S V DGT C + ++CV+G C G + ++ GS +
Sbjct: 248 LPADVCKLTCRAKGTGYYVVFSPKVTDGTEC-RPYSNSVCVRGKCVRTGCDGII-GSKLQ 305
Query: 371 ELRCG--------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN-----YI 511
+CG + G F+K GYT V +P GA I V + + + Y+
Sbjct: 306 YDKCGVCGGDNSSCTKIVGTFNKK--SKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYL 363
Query: 512 ALRLSNSSYILNGEFAVS-APGMYEAAGAIFLYTRTAGLDN-VHANG 646
AL+ N Y++NG++ +S + + + G + Y+ + D+ +H G
Sbjct: 364 ALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMG 410
>BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 77.4 bits (182), Expect = 5e-14
Identities = 63/227 (27%), Positives = 101/227 (44%), Gaps = 23/227 (10%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFD--RRPFRG--RFYTWIPYVDGN 202
R + C G Y C+ PC + R EQC + + + +G F W+P G
Sbjct: 600 RNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGV 659
Query: 203 AP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSR 370
P C L CR G +Y S V DGT C ++CV+G C G + ++ GS +
Sbjct: 660 LPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYS-NSVCVRGKCVRTGCDGII-GSKLQ 717
Query: 371 ELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN-----YI 511
+CG + G F+K GYT V +P GA I V + + + Y+
Sbjct: 718 YDKCGVCGGDNSSCTKIVGTFNKKSK--GYTDVVRIPEGATHIKVRQFKAKDQTRFTAYL 775
Query: 512 ALRLSNSSYILNGEFAVS-APGMYEAAGAIFLYTRTAGLDN-VHANG 646
AL+ N Y++NG++ +S + + + G + Y+ + D+ +H G
Sbjct: 776 ALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMG 822
>BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 77.4 bits (182), Expect = 5e-14
Identities = 63/227 (27%), Positives = 101/227 (44%), Gaps = 23/227 (10%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFD--RRPFRG--RFYTWIPYVDGN 202
R + C G Y C+ PC + R EQC + + + +G F W+P G
Sbjct: 600 RNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGV 659
Query: 203 AP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSR 370
P C L CR G +Y S V DGT C ++CV+G C G + ++ GS +
Sbjct: 660 LPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYS-NSVCVRGKCVRTGCDGII-GSKLQ 717
Query: 371 ELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN-----YI 511
+CG + G F+K GYT V +P GA I V + + + Y+
Sbjct: 718 YDKCGVCGGDNSSCTKIVGTFNKKSK--GYTDVVRIPEGATHIKVRQFKAKDQTRFTAYL 775
Query: 512 ALRLSNSSYILNGEFAVS-APGMYEAAGAIFLYTRTAGLDN-VHANG 646
AL+ N Y++NG++ +S + + + G + Y+ + D+ +H G
Sbjct: 776 ALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMG 822
>AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein.
Length = 930
Score = 77.4 bits (182), Expect = 5e-14
Identities = 63/227 (27%), Positives = 101/227 (44%), Gaps = 23/227 (10%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFD--RRPFRG--RFYTWIPYVDGN 202
R + C G Y C+ PC + R EQC + + + +G F W+P G
Sbjct: 600 RNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGV 659
Query: 203 AP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSR 370
P C L CR G +Y S V DGT C ++CV+G C G + ++ GS +
Sbjct: 660 LPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYS-NSVCVRGKCVRTGCDGII-GSKLQ 717
Query: 371 ELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN-----YI 511
+CG + G F+K GYT V +P GA I V + + + Y+
Sbjct: 718 YDKCGVCGGDNSSCTKIVGTFNKKSK--GYTDVVRIPEGATHIKVRQFKAKDQTRFTAYL 775
Query: 512 ALRLSNSSYILNGEFAVS-APGMYEAAGAIFLYTRTAGLDN-VHANG 646
AL+ N Y++NG++ +S + + + G + Y+ + D+ +H G
Sbjct: 776 ALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMG 822
>AP001697-2|BAA95503.1| 517|Homo sapiens disintegrin-like and
metalloprotease with thrombospondin type 1 motif, 5
protein.
Length = 517
Score = 77.0 bits (181), Expect = 7e-14
Identities = 63/227 (27%), Positives = 101/227 (44%), Gaps = 23/227 (10%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFD--RRPFRG--RFYTWIPYVDGN 202
R + C G Y C+ PC + R EQC + + + +G F W+P G
Sbjct: 187 RNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGV 246
Query: 203 AP---CALNCRPMGQQFYATLSI-VDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSR 370
P C L CR G +Y S V DGT C ++CV+G C G + ++ GS +
Sbjct: 247 LPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYS-NSVCVRGKCVRTGCDGII-GSKLQ 304
Query: 371 ELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSEN-----YI 511
+CG + G F+K GYT V +P GA I V + + + Y+
Sbjct: 305 YDKCGVCGGDNSSCTKIVGTFNKKSK--GYTDVVRIPEGATHIKVRQFKAKDQTRFTAYL 362
Query: 512 ALRLSNSSYILNGEFAVS-APGMYEAAGAIFLYTRTAGLDN-VHANG 646
AL+ N Y++NG++ +S + + + G + Y+ + D+ +H G
Sbjct: 363 ALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMG 409
>BC094811-1|AAH94811.1| 602|Homo sapiens ADAMTSL4 protein protein.
Length = 602
Score = 76.2 bits (179), Expect = 1e-13
Identities = 38/102 (37%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
Frame = +2
Query: 389 RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFAVSA 568
RLVSG + PLGY + +P GA R+ + +L S NY+ALR I+NG +AV
Sbjct: 13 RLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP 72
Query: 569 PGMYEAAGAIFLYTR----TAGLDNVHANGPIYHPIDIMILY 682
PG Y A G +F Y R +++ A GP P+D+ +++
Sbjct: 73 PGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIF 114
>BC071852-1|AAH71852.1| 602|Homo sapiens ADAMTSL4 protein protein.
Length = 602
Score = 76.2 bits (179), Expect = 1e-13
Identities = 38/102 (37%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
Frame = +2
Query: 389 RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFAVSA 568
RLVSG + PLGY + +P GA R+ + +L S NY+ALR I+NG +AV
Sbjct: 13 RLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP 72
Query: 569 PGMYEAAGAIFLYTR----TAGLDNVHANGPIYHPIDIMILY 682
PG Y A G +F Y R +++ A GP P+D+ +++
Sbjct: 73 PGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIF 114
>AK131414-1|BAD18561.1| 493|Homo sapiens protein ( Homo sapiens
cDNA FLJ16524 fis, clone OCBBF2003327, moderately
similar to ADAM-TS 6 precursor (EC 3.4.24.-). ).
Length = 493
Score = 75.4 bits (177), Expect = 2e-13
Identities = 55/167 (32%), Positives = 79/167 (47%), Gaps = 10/167 (5%)
Frame = +2
Query: 209 CALNCRPMGQQFYAT-LSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRC- 382
C+L C G FY + V DGTPC D + ICV G CK +G + VL GS+ RE +C
Sbjct: 126 CSLTCLAEGFNFYTERAAAVVDGTPCRPDTVD-ICVSGECKHVGCDRVL-GSDLREDKCR 183
Query: 383 -------GRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYI 541
+ G+FS GY V +P+G+ I + +L S N++AL+ S +
Sbjct: 184 VCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLNHLALKGDQESLL 243
Query: 542 LNGEFAVSAPGMYEAAGAIF-LYTRTAGLDNVHANGPIYHPIDIMIL 679
L G P AG F L + ++ A GPI + +M+L
Sbjct: 244 LEGLPGTPQPHRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVL 290
>BC030262-1|AAH30262.1| 439|Homo sapiens ADAMTS-like 1 protein.
Length = 439
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/116 (34%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYV-DGNAPCALN 220
+K C G + RY C+ C + RA+QCS+ + G+FY W+P D + PC+L
Sbjct: 63 SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCSLK 122
Query: 221 CRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
C+ G L+ V DGT C + L +C+ G C+++G + L GS +E CG
Sbjct: 123 CQAKGTTLVVELAPKVLDGTRCYTESLD-MCISGLCQIVGCDHQL-GSTVKEDNCG 176
>AY358327-1|AAQ88693.1| 525|Homo sapiens ADAMTSL1 protein.
Length = 525
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/116 (34%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYV-DGNAPCALN 220
+K C G + RY C+ C + RA+QCS+ + G+FY W+P D + PC+L
Sbjct: 63 SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCSLK 122
Query: 221 CRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
C+ G L+ V DGT C + L +C+ G C+++G + L GS +E CG
Sbjct: 123 CQAKGTTLVVELAPKVLDGTRCYTESLD-MCISGLCQIVGCDHQL-GSTVKEDNCG 176
>AL353895-1|CAI14851.1| 525|Homo sapiens ADAMTS-like 1 protein.
Length = 525
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/116 (34%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYV-DGNAPCALN 220
+K C G + RY C+ C + RA+QCS+ + G+FY W+P D + PC+L
Sbjct: 63 SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCSLK 122
Query: 221 CRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
C+ G L+ V DGT C + L +C+ G C+++G + L GS +E CG
Sbjct: 123 CQAKGTTLVVELAPKVLDGTRCYTESLD-MCISGLCQIVGCDHQL-GSTVKEDNCG 176
>AF176313-1|AAK84170.1| 525|Homo sapiens ADAM-TS related protein 1
protein.
Length = 525
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/116 (34%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Frame = +2
Query: 44 NKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYV-DGNAPCALN 220
+K C G + RY C+ C + RA+QCS+ + G+FY W+P D + PC+L
Sbjct: 63 SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCSLK 122
Query: 221 CRPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG 385
C+ G L+ V DGT C + L +C+ G C+++G + L GS +E CG
Sbjct: 123 CQAKGTTLVVELAPKVLDGTRCYTESLD-MCISGLCQIVGCDHQL-GSTVKEDNCG 176
>AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ16363 fis, clone THYMU2031139, weakly similar
to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
mRNA. ).
Length = 502
Score = 72.1 bits (169), Expect = 2e-12
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 11/164 (6%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCRPM 232
C G + C PC G+ + R +QC + DR + + VD + PC L C P+
Sbjct: 339 CPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVD-DKPCELYCSPL 397
Query: 233 GQQFYATLSIVD---DGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG------ 385
G++ + L + D DGTPC +CV G C+ IG + ++ GS ++E RCG
Sbjct: 398 GKE--SPLLVADRVLDGTPCGPYETD-LCVHGKCQKIGCDGII-GSAAKEDRCGVCSGDG 453
Query: 386 --RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYI 511
L G FS R GY A +P GA RI V E + +++
Sbjct: 454 KTCHLAKGDFSHAR-GTGYIEAAVIPAGARRIRVVEDKPAHSFL 496
>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif 17 protein.
Length = 1095
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/215 (26%), Positives = 94/215 (43%), Gaps = 3/215 (1%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCRPM 232
C G + C PC G+ + R +QC + DR + + VD + PC L C P+
Sbjct: 582 CPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVD-DKPCELYCSPL 640
Query: 233 GQQFYATLSIVD---DGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGRRLVSG 403
G++ + L + D DGTPC +CV G C+ IG + ++ GS ++E RCG
Sbjct: 641 GKE--SPLLVADRVLDGTPCGPYETD-LCVHGKCQKIGCDGII-GSAAKEDRCG------ 690
Query: 404 LFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFAVSAPGMYE 583
V + C + + + + AL+ S I N ++ + PG ++
Sbjct: 691 -------------VCSGDGKTCHLVKGDFSHARG-TALKDSGKGSI-NSDWKIELPGEFQ 735
Query: 584 AAGAIFLYTRTAGLDNVHANGPIYHPIDIMILYTH 688
AG Y R + + A GP P+ +M+L H
Sbjct: 736 IAGTTVRYVRRGLWEKISAKGPTKLPLHLMVLLFH 770
>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disintegrin
17, with thrombospondin domains protein.
Length = 1095
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/215 (26%), Positives = 94/215 (43%), Gaps = 3/215 (1%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCALNCRPM 232
C G + C PC G+ + R +QC + DR + + VD + PC L C P+
Sbjct: 582 CPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVD-DKPCELYCSPL 640
Query: 233 GQQFYATLSIVD---DGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCGRRLVSG 403
G++ + L + D DGTPC +CV G C+ IG + ++ GS ++E RCG
Sbjct: 641 GKE--SPLLVADRVLDGTPCGPYETD-LCVHGKCQKIGCDGII-GSAAKEDRCG------ 690
Query: 404 LFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYILNGEFAVSAPGMYE 583
V + C + + + + AL+ S I N ++ + PG ++
Sbjct: 691 -------------VCSGDGKTCHLVKGDFSHARG-TALKDSGKGSI-NSDWKIELPGEFQ 735
Query: 584 AAGAIFLYTRTAGLDNVHANGPIYHPIDIMILYTH 688
AG Y R + + A GP P+ +M+L H
Sbjct: 736 IAGTTVRYVRRGLWEKISAKGPTKLPLHLMVLLFH 770
>AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.
Length = 1502
Score = 70.1 bits (164), Expect = 8e-12
Identities = 52/191 (27%), Positives = 88/191 (46%), Gaps = 20/191 (10%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRR--PFRG--RFYTWIPYVDG---NAPC 211
C+G ++ CNT C G + R +QCS F+ + G W+P G C
Sbjct: 595 CVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGVGTKDRC 654
Query: 212 ALNCRPMG-QQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG- 385
L C+ G FY +V+DGTPC + C K G + VL S+++ +CG
Sbjct: 655 KLYCQVAGTNYFYLLKDMVEDGTPCGTESYNIDC-NCVLKAAGCDHVL-NSSAKIDKCGV 712
Query: 386 -------RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASS----ENYIALRLSNS 532
+ ++G+F+ GY V +P GA +++ + + S ++Y+AL +
Sbjct: 713 CGGDNSSCKTITGVFNSSH--YGYNVVVKIPAGATNVDIRQYSYSGQPDDSYLALSDAEG 770
Query: 533 SYILNGEFAVS 565
+++ NG F +S
Sbjct: 771 NFLFNGNFLLS 781
>AK131403-1|BAD18550.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16501 fis, clone FEBRA2006519, weakly similar
to Mus musculus papilin mRNA. ).
Length = 415
Score = 68.1 bits (159), Expect = 3e-11
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 9/176 (5%)
Frame = +2
Query: 179 WIPYVDGNAPCALNCRPMGQQFYATLSIVDDGTPCTQDGLPAICVQGTCKVIGRESVLAG 358
W +D N C R + F+A V DGTPC+ + +C+ G C+++G + L G
Sbjct: 54 WKRKIDAN--CTARLRTLNF-FFAMSGKVKDGTPCSPNKND-VCIDGVCELVGCDHEL-G 108
Query: 359 SNSRELRCGR--------RLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIA 514
S + CG + GL+ Y V +P GA I + EL S +Y+A
Sbjct: 109 SKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPVVLIPAGARSIEIQELQVSSSYLA 168
Query: 515 LRLSNSSYILNGEFAVSAPGMYEAAGAIFLYTRTAGL-DNVHANGPIYHPIDIMIL 679
+R + + L G +++ PG + AG F Y R+ + ++A GP + IL
Sbjct: 169 VRSLSQKHYLTGGWSIDWPGEFPFAGTTFEYQRSFNRPERLYAPGPTNETLVFEIL 224
>AL358817-5|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1223
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 591 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 650
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 651 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 709
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 710 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 769
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 770 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 811
>AL358817-4|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1226
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 594 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 653
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 654 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 712
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 713 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 772
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 773 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 814
>AL355344-5|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1223
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 591 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 650
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 651 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 709
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 710 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 769
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 770 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 811
>AL355344-4|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1226
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 594 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 653
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 654 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 712
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 713 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 772
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 773 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 814
>AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disintegrin
protease protein.
Length = 1223
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 591 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 650
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 651 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 709
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 710 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 769
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 770 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 811
>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
Length = 1159
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 527 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 586
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 587 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 645
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 646 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 705
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 706 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 747
>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motif 14 prec
protein.
Length = 1223
Score = 67.3 bits (157), Expect = 5e-11
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 13/222 (5%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 591 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 650
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 651 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 709
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLS-NSSYILNGE 553
R V G K G + +P GA I + L S + I ++ S+ILN +
Sbjct: 710 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRIVVKNQVTGSFILNPK 769
Query: 554 FAVSAPGMYEAAGAIFLYTRTAGLDNVHANGPIYHPIDIMIL 679
+ + A G + +++ +GP+ I I+ L
Sbjct: 770 GKEATSRTFTAMGLEWEDAVEDAKESLKTSGPLPEAIAILAL 811
>AY358118-1|AAQ88485.1| 1097|Homo sapiens ADAMTS13 protein.
Length = 1097
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L +EQC+ D +P R FY W +P+ G+
Sbjct: 91 RACVGADLQAEMCNTQACEKTQLEFMSEQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 150
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 151 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 210
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 211 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 262
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 263 T-HLAVRIGGRYVVAGKMSISPNT 285
>BC042057-1|AAH42057.1| 129|Homo sapiens PAPLN protein protein.
Length = 129
Score = 66.1 bits (154), Expect = 1e-10
Identities = 27/65 (41%), Positives = 34/65 (52%)
Frame = +2
Query: 35 RQINKGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIPYVDGNAPCA 214
R C+G R + C T+ C G + RAEQC+ FD F+GR Y W+PY C
Sbjct: 58 RDGGSSCVGPARSHRSCRTESCPDGARDFRAEQCAEFDGAEFQGRRYRWLPYYSAPNKCE 117
Query: 215 LNCRP 229
LNC P
Sbjct: 118 LNCIP 122
>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
factor-cleaving protease precursor protein.
Length = 1427
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1340
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 390 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 449
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 450 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 509
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 510 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 561
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 562 T-HLAVRIGGRYVVAGKMSISPNT 584
>AL158826-24|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AL158826-23|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AL158826-22|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1340
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 390 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 449
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 450 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 509
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 510 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 561
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 562 T-HLAVRIGGRYVVAGKMSISPNT 584
>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant 2
protein.
Length = 1371
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
Length = 1340
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 390 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 449
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 450 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 509
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 510 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 561
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 562 T-HLAVRIGGRYVVAGKMSISPNT 584
>AJ011374-1|CAB66157.1| 364|Homo sapiens hypothetical protein
protein.
Length = 364
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 93 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 152
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 153 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 212
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 213 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 264
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 265 T-HLAVRIGGRYVVAGKMSISPNT 287
>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
Length = 1427
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
factor-cleaving protease protein.
Length = 1427
Score = 65.7 bits (153), Expect = 2e-10
Identities = 57/204 (27%), Positives = 87/204 (42%), Gaps = 14/204 (6%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFR-----GRFYTW---IPYVDGN 202
+ C+G D + CNTQ C L ++QC+ D +P R FY W +P+ G+
Sbjct: 421 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD 480
Query: 203 APCALNCRPMGQQFYATL-SIVDDGTPC-----TQDGLPAICVQGTCKVIGRESVLAGSN 364
A C CR +G+ F DGT C +DG ++CV G+C+ G + +
Sbjct: 481 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ 540
Query: 365 SRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYIALRLSNSSYIL 544
+ RC V G + P +F A G R VT L + N ++ ++N +
Sbjct: 541 VWD-RC---QVCGGDNSTCSPRKGSFTA----GRAREYVTFLTVTPNLTSVYIANHRPLF 592
Query: 545 NGEFAVSAPGMYEAAGAIFLYTRT 616
AV G Y AG + + T
Sbjct: 593 T-HLAVRIGGRYVVAGKMSISPNT 615
>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
Length = 1509
Score = 60.9 bits (141), Expect = 5e-09
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Frame = +2
Query: 431 GYTFVATVPRGACRINVTELASSENYIALRLSN-SSYILNGEFAVSAPGMYEAAGAIFLY 607
GY + +P+GA I V E+ + N++A+R + Y LNG F + G Y+ AG +F Y
Sbjct: 630 GYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQY 689
Query: 608 TRTAGLDNVHANGPIYHPIDIMILY 682
R L+ + A GP + I +L+
Sbjct: 690 DRKGDLEKLMATGPTNESVWIQLLF 714
Score = 48.0 bits (109), Expect = 3e-05
Identities = 19/47 (40%), Positives = 22/47 (46%)
Frame = +2
Query: 47 KGCLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDRRPFRGRFYTWIP 187
K C G +RY CN PC R QCS FD P++ Y W P
Sbjct: 579 KYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFP 625
>AK128469-1|BAC87455.1| 327|Homo sapiens protein ( Homo sapiens
cDNA FLJ46613 fis, clone TKIDN2011160, moderately
similar to ADAM-TS 3 precursor (EC 3.4.24.-). ).
Length = 327
Score = 59.3 bits (137), Expect = 1e-08
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 12/165 (7%)
Frame = +2
Query: 53 CLGVDRRYHECNTQPCAGGVLNTRAEQCSSFDR-RPFRGRFYTWIPYV--DGNAPCALNC 223
CLG Y CN++ C G + RA+QC+ + + ++W+PY D C L C
Sbjct: 114 CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNSYYVHQNAKHSWVPYEPDDDAQKCELIC 173
Query: 224 RPMGQQFYATLS-IVDDGTPCTQDGLPAICVQGTCKVIGRESVLAGSNSRELRCG----- 385
+ ++ +V DGT C+ ++C +G C +G + + GS + +CG
Sbjct: 174 QSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPVGCDKEV-GSMKADDKCGVCGGD 232
Query: 386 ---RRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELASSENYI 511
R V G K G + +P GA I + L S + I
Sbjct: 233 NSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQIEALEKSPHRI 277
>BC139833-1|AAI39834.1| 240|Homo sapiens ADAMTSL5 protein protein.
Length = 240
Score = 49.2 bits (112), Expect = 2e-05
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Frame = +2
Query: 536 YILNGEFAVSAPGMYEAAGAIFLYTRTAG-LDNVHANGPIYHPIDIMILYTHP 691
Y+LNG + VS PG YEAAG +YTR G + + A GP H + + +L P
Sbjct: 7 YVLNGHWVVSPPGTYEAAGTHVVYTRDTGPQETLQAAGPTSHDLLLQVLLQEP 59
>BC119796-1|AAI19797.1| 131|Homo sapiens ADAMTSL5 protein protein.
Length = 131
Score = 49.2 bits (112), Expect = 2e-05
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Frame = +2
Query: 536 YILNGEFAVSAPGMYEAAGAIFLYTRTAG-LDNVHANGPIYHPIDIMILYTHP 691
Y+LNG + VS PG YEAAG +YTR G + + A GP H + + +L P
Sbjct: 7 YVLNGHWVVSPPGTYEAAGTHVVYTRDTGPQETLQAAGPTSHDLLLQVLLQEP 59
>AY358143-1|AAQ88510.1| 219|Homo sapiens FVSY9334 protein.
Length = 219
Score = 41.5 bits (93), Expect = 0.003
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +2
Query: 317 GTCKVIGRESVLAGSNSRELRCGRRLVSGLFSKPRLPLGYTFVATVPRGACRINVTELAS 496
G+ KV+ + V G N+ G ++VSG+F LGY V +P GA +IN+TE+
Sbjct: 33 GSDKVVDKCGVCGGDNT-----GCQVVSGVFKHALTSLGYHRVVEIPEGATKINITEMYK 87
Query: 497 S 499
S
Sbjct: 88 S 88
>AL031658-2|CAI42577.1| 234|Homo sapiens tubulin tyrosine
ligase-like family, member 9 protein.
Length = 234
Score = 33.1 bits (72), Expect = 1.1
Identities = 13/26 (50%), Positives = 18/26 (69%)
Frame = +2
Query: 500 ENYIALRLSNSSYILNGEFAVSAPGM 577
ENY+A R + Y++ GE AVSAP +
Sbjct: 168 ENYVAQRYIENPYLIGGEMAVSAPAL 193
>CR456466-1|CAG30352.1| 1211|Homo sapiens dJ402G11.8 protein.
Length = 1211
Score = 31.1 bits (67), Expect = 4.3
Identities = 10/24 (41%), Positives = 19/24 (79%)
Frame = +1
Query: 370 GAEMWKKARFRIVLETSTATGLHF 441
G ++WK +RFRI++ T +++GL +
Sbjct: 848 GEDIWKASRFRIIITTCSSSGLFY 871
>BC150137-1|AAI50138.1| 1165|Homo sapiens MOV10L1 protein protein.
Length = 1165
Score = 31.1 bits (67), Expect = 4.3
Identities = 10/24 (41%), Positives = 19/24 (79%)
Frame = +1
Query: 370 GAEMWKKARFRIVLETSTATGLHF 441
G ++WK +RFRI++ T +++GL +
Sbjct: 848 GEDIWKASRFRIIITTCSSSGLFY 871
>AL034546-1|CAI23226.1| 1211|Homo sapiens protein ( Human DNA
sequence from clone RP5-898I4 on chromosome 22q13.33. ).
Length = 1211
Score = 31.1 bits (67), Expect = 4.3
Identities = 10/24 (41%), Positives = 19/24 (79%)
Frame = +1
Query: 370 GAEMWKKARFRIVLETSTATGLHF 441
G ++WK +RFRI++ T +++GL +
Sbjct: 848 GEDIWKASRFRIIITTCSSSGLFY 871
>AL022328-1|CAI42752.1| 1211|Homo sapiens protein ( Human DNA
sequence from clone RP3-402G11 on chromosome
22q13.31-13.33. ).
Length = 1211
Score = 31.1 bits (67), Expect = 4.3
Identities = 10/24 (41%), Positives = 19/24 (79%)
Frame = +1
Query: 370 GAEMWKKARFRIVLETSTATGLHF 441
G ++WK +RFRI++ T +++GL +
Sbjct: 848 GEDIWKASRFRIIITTCSSSGLFY 871
>AF285604-1|AAK31983.1| 1211|Homo sapiens MOV10-like 1 protein.
Length = 1211
Score = 31.1 bits (67), Expect = 4.3
Identities = 10/24 (41%), Positives = 19/24 (79%)
Frame = +1
Query: 370 GAEMWKKARFRIVLETSTATGLHF 441
G ++WK +RFRI++ T +++GL +
Sbjct: 848 GEDIWKASRFRIIITTCSSSGLFY 871
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,885,703
Number of Sequences: 237096
Number of extensions: 2672345
Number of successful extensions: 6526
Number of sequences better than 10.0: 113
Number of HSP's better than 10.0 without gapping: 6001
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6294
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8679165170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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