Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0973
(762 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X72389-1|CAA51082.1| 393|Homo sapiens 4-hydroxyphenylpyruvate d... 244 2e-64
D31628-1|BAA06498.1| 393|Homo sapiens 4-hydroxyphenylpyruvic ac... 244 2e-64
BC024287-1|AAH24287.1| 393|Homo sapiens 4-hydroxyphenylpyruvate... 244 2e-64
U29895-1|AAC73008.1| 393|Homo sapiens 4-hydroxyphenylpyruvate-d... 244 4e-64
BC007293-1|AAH07293.1| 371|Homo sapiens 4-hydroxyphenylpyruvate... 41 0.006
AL359540-1|CAI21712.1| 371|Homo sapiens 4-hydroxyphenylpyruvate... 41 0.006
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 31 4.5
AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-... 31 4.5
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 31 4.5
>X72389-1|CAA51082.1| 393|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase protein.
Length = 393
Score = 244 bits (598), Expect = 2e-64
Identities = 108/200 (54%), Positives = 144/200 (72%), Gaps = 1/200 (0%)
Frame = +2
Query: 38 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 217
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 218 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 397
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 398 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQL-LEKDPISKYLPKVEINF 574
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
Query: 575 IDHIVGNQPENEMEEAASWY 634
IDHIVGNQP+ EM A+ WY
Sbjct: 181 IDHIVGNQPDQEMVSASEWY 200
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 45/57 (78%)
Frame = +1
Query: 592 EPARERNGGSRFVVRKMPPFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPINEP 762
+P +E S + ++ + FHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PINEP
Sbjct: 188 QPDQEMVSASEWYLKNLQ-FHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEP 243
>D31628-1|BAA06498.1| 393|Homo sapiens 4-hydroxyphenylpyruvic acid
dioxgenase (HPD) protein.
Length = 393
Score = 244 bits (598), Expect = 2e-64
Identities = 108/200 (54%), Positives = 144/200 (72%), Gaps = 1/200 (0%)
Frame = +2
Query: 38 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 217
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 218 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 397
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 398 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQL-LEKDPISKYLPKVEINF 574
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
Query: 575 IDHIVGNQPENEMEEAASWY 634
IDHIVGNQP+ EM A+ WY
Sbjct: 181 IDHIVGNQPDQEMVSASEWY 200
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 45/57 (78%)
Frame = +1
Query: 592 EPARERNGGSRFVVRKMPPFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPINEP 762
+P +E S + ++ + FHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PINEP
Sbjct: 188 QPDQEMVSASEWYLKNLQ-FHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEP 243
>BC024287-1|AAH24287.1| 393|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase protein.
Length = 393
Score = 244 bits (598), Expect = 2e-64
Identities = 108/200 (54%), Positives = 144/200 (72%), Gaps = 1/200 (0%)
Frame = +2
Query: 38 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 217
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 218 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 397
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 398 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQL-LEKDPISKYLPKVEINF 574
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
Query: 575 IDHIVGNQPENEMEEAASWY 634
IDHIVGNQP+ EM A+ WY
Sbjct: 181 IDHIVGNQPDQEMVSASEWY 200
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 45/57 (78%)
Frame = +1
Query: 592 EPARERNGGSRFVVRKMPPFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPINEP 762
+P +E S + ++ + FHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PINEP
Sbjct: 188 QPDQEMVSASEWYLKNLQ-FHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEP 243
>U29895-1|AAC73008.1| 393|Homo sapiens
4-hydroxyphenylpyruvate-dioxygenase protein.
Length = 393
Score = 244 bits (596), Expect = 4e-64
Identities = 108/200 (54%), Positives = 144/200 (72%), Gaps = 1/200 (0%)
Frame = +2
Query: 38 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 217
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 218 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 397
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 398 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQ-LLEKDPISKYLPKVEINF 574
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEPPAFMDPLLPKLPKCSLEM 180
Query: 575 IDHIVGNQPENEMEEAASWY 634
IDHIVGNQP+ EM A+ WY
Sbjct: 181 IDHIVGNQPDQEMVSASEWY 200
Score = 72.9 bits (171), Expect = 1e-12
Identities = 32/57 (56%), Positives = 45/57 (78%)
Frame = +1
Query: 592 EPARERNGGSRFVVRKMPPFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPINEP 762
+P +E S + ++ + FHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PINEP
Sbjct: 188 QPDQEMVSASEWYLKNLQ-FHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEP 243
>BC007293-1|AAH07293.1| 371|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase-like protein.
Length = 371
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 1/184 (0%)
Frame = +2
Query: 98 HVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPVET 277
H+ F V + A FGF+PLA ++ G RQ+ A+R +F+ E
Sbjct: 10 HIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGSGEP 65
Query: 278 EFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKT-Y 454
+ + ++ F V + G V +D G A + +
Sbjct: 66 LYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPA 125
Query: 455 GSNTHTLVDRSKYTGPFLPGYQLLEKDPISKYLPKVEINFIDHIVGNQPENEMEEAASWY 634
G + TL++R+ Y GPFLPG++ P+S ++ +DH+ W+
Sbjct: 126 GILSLTLLERAGYRGPFLPGFR-----PVSSAPGPGWVSRVDHLTLACTPGSSPTLLRWF 180
Query: 635 ERCL 646
CL
Sbjct: 181 HDCL 184
>AL359540-1|CAI21712.1| 371|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase-like protein.
Length = 371
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 1/184 (0%)
Frame = +2
Query: 98 HVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPVET 277
H+ F V + A FGF+PLA ++ G RQ+ A+R +F+ E
Sbjct: 10 HIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGSGEP 65
Query: 278 EFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKT-Y 454
+ + ++ F V + G V +D G A + +
Sbjct: 66 LYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPA 125
Query: 455 GSNTHTLVDRSKYTGPFLPGYQLLEKDPISKYLPKVEINFIDHIVGNQPENEMEEAASWY 634
G + TL++R+ Y GPFLPG++ P+S ++ +DH+ W+
Sbjct: 126 GILSLTLLERAGYRGPFLPGFR-----PVSSAPGPGWVSRVDHLTLACTPGSSPTLLRWF 180
Query: 635 ERCL 646
CL
Sbjct: 181 HDCL 184
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 31.1 bits (67), Expect = 4.5
Identities = 19/79 (24%), Positives = 40/79 (50%)
Frame = +2
Query: 179 SGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYIL 358
S L +++S R +I + ++E ++ + H D VK V +VE+L Y+L
Sbjct: 1638 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 1694
Query: 359 EYARKQGAKVVKDLWEEKD 415
+ ++K+ + +L +K+
Sbjct: 1695 DQSQKESQCLKSELQAQKE 1713
>AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-2
protein.
Length = 761
Score = 31.1 bits (67), Expect = 4.5
Identities = 19/79 (24%), Positives = 40/79 (50%)
Frame = +2
Query: 179 SGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYIL 358
S L +++S R +I + ++E ++ + H D VK V +VE+L Y+L
Sbjct: 13 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 69
Query: 359 EYARKQGAKVVKDLWEEKD 415
+ ++K+ + +L +K+
Sbjct: 70 DQSQKESQCLKSELQAQKE 88
>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
Length = 1540
Score = 31.1 bits (67), Expect = 4.5
Identities = 19/79 (24%), Positives = 40/79 (50%)
Frame = +2
Query: 179 SGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYIL 358
S L +++S R +I + ++E ++ + H D VK V +VE+L Y+L
Sbjct: 699 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 755
Query: 359 EYARKQGAKVVKDLWEEKD 415
+ ++K+ + +L +K+
Sbjct: 756 DQSQKESQCLKSELQAQKE 774
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 121,336,664
Number of Sequences: 237096
Number of extensions: 2755366
Number of successful extensions: 5813
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5579
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5807
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9144232952
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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