Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0825
(788 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O15379 Cluster: Histone deacetylase 3; n=149; Eukaryota... 313 3e-84
UniRef50_UPI000065D235 Cluster: Histone deacetylase 1 (HD1).; n=... 272 9e-72
UniRef50_Q13547 Cluster: Histone deacetylase 1; n=60; Fungi/Meta... 268 8e-71
UniRef50_Q92769 Cluster: Histone deacetylase 2; n=50; Eukaryota|... 266 6e-70
UniRef50_A2FDZ0 Cluster: Acetylpolyamine aminohydrolase, putativ... 236 5e-61
UniRef50_A3BWV6 Cluster: Putative uncharacterized protein; n=2; ... 234 2e-60
UniRef50_P53096 Cluster: Probable histone deacetylase HOS2; n=15... 231 1e-59
UniRef50_Q09440 Cluster: Putative histone deacetylase 2; n=2; Ca... 225 1e-57
UniRef50_Q5U8M9 Cluster: Histone deacetylase 1; n=2; Entamoeba h... 221 1e-56
UniRef50_Q4WHY0 Cluster: Histone deacetylase HosA; n=15; Fungi/M... 217 3e-55
UniRef50_Q5KKR8 Cluster: Histone deacetylase 1-1 (Hd1), putative... 168 2e-54
UniRef50_Q9HDT2 Cluster: Histone deacetylase; n=4; Fungi/Metazoa... 212 1e-53
UniRef50_Q5XTS3 Cluster: Histone deacetylase HDAC; n=2; Giardia ... 207 2e-52
UniRef50_Q0V6A5 Cluster: Putative uncharacterized protein; n=2; ... 198 1e-49
UniRef50_A4RK28 Cluster: Putative uncharacterized protein; n=1; ... 194 3e-48
UniRef50_A4VDD9 Cluster: Histone deacetylase 1, 2 ,3; n=4; Oligo... 180 4e-44
UniRef50_A0DPM0 Cluster: Chromosome undetermined scaffold_59, wh... 175 1e-42
UniRef50_Q8SQN9 Cluster: HISTONE DEACETYLASE; n=1; Encephalitozo... 165 8e-40
UniRef50_Q94D35 Cluster: Histone deacetylase-like; n=9; Oryza sa... 161 2e-38
UniRef50_A0CXG2 Cluster: Chromosome undetermined scaffold_30, wh... 159 1e-37
UniRef50_A0PAD5 Cluster: Putative uncharacterized protein; n=2; ... 156 5e-37
UniRef50_Q9BY41 Cluster: Histone deacetylase 8; n=40; Eumetazoa|... 153 5e-36
UniRef50_Q98RL4 Cluster: Histone deacetylase; n=1; Guillardia th... 152 8e-36
UniRef50_UPI0000587266 Cluster: PREDICTED: similar to Histone de... 134 2e-30
UniRef50_O88895-2 Cluster: Isoform Short of O88895 ; n=6; Eutele... 128 2e-28
UniRef50_A3C9I4 Cluster: Putative uncharacterized protein; n=6; ... 128 2e-28
UniRef50_Q4QAJ4 Cluster: Histone deacetylase, putative; n=3; Lei... 121 2e-26
UniRef50_Q4QCE7 Cluster: Histone deacetylase, putative; n=7; Try... 118 1e-25
UniRef50_Q17CU3 Cluster: Histone deacetylase; n=2; Aedes aegypti... 118 2e-25
UniRef50_Q74DU3 Cluster: Histone deacetylase/AcuC/AphA family pr... 113 4e-24
UniRef50_A0B926 Cluster: Histone deacetylase superfamily; n=1; M... 111 2e-23
UniRef50_UPI0000D55D9C Cluster: PREDICTED: similar to histone de... 110 3e-23
UniRef50_Q6C3Y5 Cluster: Similar to CA1453|CaHOS1 Candida albica... 108 1e-22
UniRef50_Q3A415 Cluster: Deacetylase; n=1; Pelobacter carbinolic... 107 3e-22
UniRef50_Q0S1K3 Cluster: Possible acetoin dehydrogenase; n=3; Ba... 98 3e-19
UniRef50_UPI000050FC36 Cluster: COG0123: Deacetylases, including... 95 1e-18
UniRef50_A0K0A0 Cluster: Histone deacetylase superfamily; n=2; A... 93 1e-17
UniRef50_A5H660 Cluster: Histone deacetylase 8; n=3; Schistosoma... 91 2e-17
UniRef50_A5DN16 Cluster: Putative uncharacterized protein; n=1; ... 90 5e-17
UniRef50_P39067 Cluster: Acetoin utilization protein acuC; n=25;... 90 5e-17
UniRef50_O67135 Cluster: Acetoin utilization protein; n=2; Aquif... 89 1e-16
UniRef50_Q2S035 Cluster: Acetoin utilization protein acuC; n=4; ... 87 4e-16
UniRef50_Q2J786 Cluster: Histone deacetylase superfamily; n=13; ... 87 5e-16
UniRef50_Q4P6M9 Cluster: Putative uncharacterized protein; n=1; ... 86 8e-16
UniRef50_Q1AX98 Cluster: Histone deacetylase superfamily; n=2; B... 85 1e-15
UniRef50_Q12214 Cluster: Histone deacetylase HOS1; n=2; Saccharo... 85 1e-15
UniRef50_UPI00005A01A4 Cluster: PREDICTED: similar to histone de... 85 2e-15
UniRef50_Q6FWB7 Cluster: Similar to sp|Q12214 Saccharomyces cere... 85 3e-15
UniRef50_Q6CVU3 Cluster: Similar to sp|Q12214 Saccharomyces cere... 83 6e-15
UniRef50_A7TRW5 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15
UniRef50_Q6BS96 Cluster: Similar to CA1453|CaHOS1 Candida albica... 81 3e-14
UniRef50_Q4R7V0 Cluster: Testis cDNA clone: QtsA-14323, similar ... 80 5e-14
UniRef50_Q75BA6 Cluster: ADL339Wp; n=1; Eremothecium gossypii|Re... 79 2e-13
UniRef50_Q981B8 Cluster: Acetylpolyamine aminohydrolase; n=4; Su... 76 1e-12
UniRef50_P64375 Cluster: Acetoin utilization protein acuC; n=15;... 75 2e-12
UniRef50_O30107 Cluster: Uncharacterized protein AF_0130; n=2; E... 73 1e-11
UniRef50_A0L9T2 Cluster: Histone deacetylase superfamily; n=3; P... 69 1e-10
UniRef50_Q59Q78 Cluster: Likely histone deacetylase Hos1p; n=2; ... 69 2e-10
UniRef50_Q381M6 Cluster: Histone deacetylase 2; n=4; Trypanosoma... 66 1e-09
UniRef50_Q5K8L3 Cluster: Histone deacetylase 3, putative; n=2; F... 65 2e-09
UniRef50_A5E4H2 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09
UniRef50_A3JCC1 Cluster: Deacetylases, including yeast histone d... 63 9e-09
UniRef50_Q64AZ9 Cluster: Deacetylase; n=1; uncultured archaeon G... 62 2e-08
UniRef50_Q28M71 Cluster: Histone deacetylase superfamily; n=15; ... 61 4e-08
UniRef50_A4BCK9 Cluster: Deacetylase, including yeast histone de... 58 3e-07
UniRef50_Q8IR37 Cluster: CG6170-PC, isoform C; n=7; Diptera|Rep:... 58 3e-07
UniRef50_Q17MD0 Cluster: Histone deacetylase; n=1; Aedes aegypti... 58 3e-07
UniRef50_A1RXP5 Cluster: Histone deacetylase superfamily; n=1; T... 58 3e-07
UniRef50_UPI0000DB73BE Cluster: PREDICTED: similar to HDAC6 CG61... 57 4e-07
UniRef50_Q8F254 Cluster: Histone deacetylase family protein; n=4... 57 4e-07
UniRef50_Q7NRU4 Cluster: Histone deacetylase; n=54; Proteobacter... 57 4e-07
UniRef50_Q7VZF1 Cluster: Histone deacetylase family protein; n=6... 56 1e-06
UniRef50_Q803K0 Cluster: Zgc:55652; n=4; Danio rerio|Rep: Zgc:55... 56 1e-06
UniRef50_Q5QWS4 Cluster: Histone deacetylase/AcuC/AphA family pr... 55 2e-06
UniRef50_Q97Z24 Cluster: Acetoin utilization protein; n=3; Sulfo... 55 2e-06
UniRef50_Q2S0V9 Cluster: Histone deacetylase/AcuC/AphA family pr... 55 2e-06
UniRef50_A6ND61 Cluster: Uncharacterized protein HDAC8; n=3; Sim... 54 5e-06
UniRef50_A7HFZ2 Cluster: Histone deacetylase superfamily; n=4; C... 53 9e-06
UniRef50_A3CT27 Cluster: Histone deacetylase superfamily; n=2; M... 52 2e-05
UniRef50_Q00UC4 Cluster: Histone deacetylase superfamily; n=2; O... 51 3e-05
UniRef50_Q57ET7 Cluster: Histone deacetylase family protein; n=3... 51 4e-05
UniRef50_Q31HC2 Cluster: Histone deacetylase family protein; n=1... 51 4e-05
UniRef50_O67877 Cluster: Acetoin utilization protein; n=3; Bacte... 50 5e-05
UniRef50_UPI00015BAE44 Cluster: histone deacetylase superfamily;... 50 7e-05
UniRef50_UPI0000F2E91A Cluster: PREDICTED: similar to histone de... 50 7e-05
UniRef50_Q0LS19 Cluster: Histone deacetylase superfamily; n=1; C... 50 9e-05
UniRef50_Q9UBN7 Cluster: Histone deacetylase 6; n=38; Eutheria|R... 49 1e-04
UniRef50_A7HL59 Cluster: Histone deacetylase superfamily; n=1; F... 49 2e-04
UniRef50_Q9K0J2 Cluster: Histone deacetylase family protein; n=4... 48 2e-04
UniRef50_Q8D858 Cluster: Histone deacetylase/AcuC/AphA family pr... 48 2e-04
UniRef50_UPI00015BB127 Cluster: histone deacetylase superfamily;... 48 3e-04
UniRef50_A6T202 Cluster: Histone deacetylase superfamily protein... 48 4e-04
UniRef50_Q0YKV4 Cluster: Histone deacetylase superfamily; n=1; G... 47 5e-04
UniRef50_A6FY71 Cluster: Histone deacetylase superfamily protein... 47 5e-04
UniRef50_Q31EP6 Cluster: Histone deacetylase family protein prec... 47 6e-04
UniRef50_Q2IF50 Cluster: Histone deacetylase superfamily; n=1; A... 47 6e-04
UniRef50_Q12GF8 Cluster: Histone deacetylase superfamily; n=6; B... 47 6e-04
UniRef50_A4C9H1 Cluster: Putative histone deacetylase family pro... 47 6e-04
UniRef50_A0Y3M1 Cluster: Histone deacetylase family protein; n=1... 47 6e-04
UniRef50_Q4FNF7 Cluster: Histone deacetylase family protein; n=5... 46 8e-04
UniRef50_A4YNH4 Cluster: Acetylpolyamine aminohydrolase; n=15; P... 46 8e-04
UniRef50_Q7RB89 Cluster: Histone deacetylase/AcuC/AphA family pr... 46 8e-04
UniRef50_Q02A43 Cluster: Histone deacetylase superfamily; n=1; S... 46 0.001
UniRef50_Q8RX28 Cluster: Histone deacetylase 5; n=4; Magnoliophy... 46 0.001
UniRef50_Q9A2B7 Cluster: Histone deacetylase family protein; n=9... 46 0.001
UniRef50_Q1IJP8 Cluster: Histone deacetylase superfamily; n=1; A... 46 0.001
UniRef50_Q015Q9 Cluster: Histone deacetylase HDA110 isoform 2; n... 45 0.002
UniRef50_Q1N4R7 Cluster: Deacetylases, including yeast histone d... 45 0.002
UniRef50_A0KLZ2 Cluster: Histone deacetylase/AcuC/AphA family pr... 45 0.002
UniRef50_UPI0000E87DA7 Cluster: histone deacetylase family prote... 44 0.003
UniRef50_Q8EFZ9 Cluster: Histone deacetylase/AcuC/AphA family pr... 44 0.003
UniRef50_Q1IMW0 Cluster: Histone deacetylase superfamily; n=2; A... 44 0.003
UniRef50_A5W9E9 Cluster: Histone deacetylase superfamily; n=17; ... 44 0.003
UniRef50_Q5KNI3 Cluster: Histone deacetylase, putative; n=2; Fil... 44 0.003
UniRef50_A6C2D6 Cluster: Deacetylase; n=1; Planctomyces maris DS... 44 0.004
UniRef50_Q6C4P0 Cluster: Similar to sp|P53973 Saccharomyces cere... 44 0.004
UniRef50_A5DRS6 Cluster: Histone deacetylase HDA1; n=7; Saccharo... 44 0.004
UniRef50_Q2LVD3 Cluster: Histone deacetylase family protein; n=1... 44 0.006
UniRef50_A5D0K9 Cluster: Deacetylases; n=1; Pelotomaculum thermo... 44 0.006
UniRef50_Q7XAX9 Cluster: HDA1; n=3; Magnoliophyta|Rep: HDA1 - Ze... 44 0.006
UniRef50_Q9VC26 Cluster: CG31119-PA; n=5; Diptera|Rep: CG31119-P... 44 0.006
UniRef50_UPI0000D56143 Cluster: PREDICTED: similar to CG6170-PA,... 43 0.008
UniRef50_Q4TFH7 Cluster: Chromosome undetermined SCAF4471, whole... 43 0.008
UniRef50_Q62HN7 Cluster: Acetylpolyamine aminohydrolase; n=53; P... 43 0.008
UniRef50_P28606 Cluster: Uncharacterized 34.1 kDa protein in gln... 43 0.008
UniRef50_Q4RSK1 Cluster: Chromosome 13 SCAF15000, whole genome s... 43 0.010
UniRef50_Q3ZWU5 Cluster: Histone deacetylase family protein; n=3... 43 0.010
UniRef50_A2WM81 Cluster: Putative uncharacterized protein; n=1; ... 43 0.010
UniRef50_A6SGS8 Cluster: Putative uncharacterized protein; n=3; ... 43 0.010
UniRef50_Q569C4 Cluster: Histone deacetylase 10; n=5; Mammalia|R... 43 0.010
UniRef50_UPI0001555A7F Cluster: PREDICTED: similar to histone de... 42 0.013
UniRef50_Q569T0 Cluster: MGC115178 protein; n=5; Tetrapoda|Rep: ... 42 0.013
UniRef50_Q15WQ0 Cluster: Histone deacetylase superfamily; n=3; G... 42 0.013
UniRef50_A4JTS4 Cluster: Histone deacetylase superfamily; n=3; B... 42 0.013
UniRef50_Q944K3 Cluster: Histone deacetylase 2; n=7; Magnoliophy... 42 0.013
UniRef50_Q3IF01 Cluster: Putative histone deacetylase family pro... 42 0.018
UniRef50_Q18477 Cluster: Putative uncharacterized protein; n=2; ... 42 0.018
UniRef50_Q5KL48 Cluster: Histone deacetylase clr3, putative; n=1... 42 0.018
UniRef50_A0B6D0 Cluster: Histone deacetylase superfamily; n=1; M... 42 0.018
UniRef50_P53973 Cluster: Histone deacetylase HDA1; n=7; Saccharo... 42 0.018
UniRef50_UPI000065FABE Cluster: Histone deacetylase 6 (HD6).; n=... 42 0.023
UniRef50_A6VZD7 Cluster: Histone deacetylase superfamily; n=2; M... 42 0.023
UniRef50_A5WHG1 Cluster: Histone deacetylase superfamily; n=17; ... 42 0.023
UniRef50_A5VD94 Cluster: Histone deacetylase superfamily; n=6; A... 42 0.023
UniRef50_A3JI99 Cluster: Putative aminohydrolase; n=1; Marinobac... 42 0.023
UniRef50_Q64BV4 Cluster: Acetoin utilization protein; n=5; Archa... 42 0.023
UniRef50_Q08BS8 Cluster: Zgc:152701; n=9; Euteleostomi|Rep: Zgc:... 41 0.031
UniRef50_Q6AKN4 Cluster: Putative uncharacterized protein; n=1; ... 41 0.031
UniRef50_P72702 Cluster: Uncharacterized protein slr0245; n=15; ... 41 0.031
UniRef50_Q4SMC8 Cluster: Chromosome 3 SCAF14553, whole genome sh... 41 0.041
UniRef50_Q1H193 Cluster: Histone deacetylase superfamily; n=2; B... 41 0.041
UniRef50_A6G5J4 Cluster: Histone deacetylase superfamily protein... 41 0.041
UniRef50_A0Z891 Cluster: Deacetylases, including yeast histone d... 41 0.041
UniRef50_Q00U49 Cluster: Histone deacetylase superfamily; n=3; O... 41 0.041
UniRef50_P56523 Cluster: Histone deacetylase clr3; n=1; Schizosa... 41 0.041
UniRef50_Q7ZYF0 Cluster: Hdac6-prov protein; n=2; Xenopus|Rep: H... 40 0.054
UniRef50_Q4PCR1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.054
UniRef50_Q4P2D6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.054
UniRef50_A2BL29 Cluster: Predicted Histone deacetylase; n=1; Hyp... 40 0.054
UniRef50_Q6AJC0 Cluster: Putative uncharacterized protein; n=1; ... 40 0.071
UniRef50_A1ID65 Cluster: Histone deacetylase family protein; n=1... 40 0.071
UniRef50_A0LGT0 Cluster: Histone deacetylase superfamily; n=1; S... 40 0.071
UniRef50_Q969S8 Cluster: Histone deacetylase 10; n=20; Euteleost... 40 0.071
UniRef50_Q2SC27 Cluster: Deacetylases, including yeast histone d... 40 0.094
UniRef50_Q10IB7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.094
UniRef50_Q7Z8L6 Cluster: Putative histone deacetylase; n=2; Pleo... 40 0.094
UniRef50_Q9HSP7 Cluster: Acetoin utilization protein; n=5; Halob... 40 0.094
UniRef50_Q4T0M8 Cluster: Chromosome undetermined SCAF10929, whol... 39 0.12
UniRef50_Q7U7V3 Cluster: Putative histone deacetylase/AcuC/AphA ... 39 0.12
UniRef50_Q1VK67 Cluster: Histone deacetylase family protein; n=1... 39 0.12
UniRef50_A1I9M7 Cluster: Histone deacetylase superfamily; n=1; C... 39 0.12
UniRef50_Q5VP96 Cluster: HGWP repeat containing protein-like; n=... 39 0.12
UniRef50_Q4QI60 Cluster: Histone deacetylase, putative; n=3; Lei... 39 0.12
UniRef50_Q7S8C9 Cluster: Putative uncharacterized protein NCU070... 39 0.12
UniRef50_UPI0000F2108C Cluster: PREDICTED: hypothetical protein;... 39 0.16
UniRef50_UPI0000E463DB Cluster: PREDICTED: similar to histone de... 39 0.16
UniRef50_UPI000023CBFE Cluster: hypothetical protein FG05636.1; ... 39 0.16
UniRef50_Q5LRW9 Cluster: Acetylpolyamine aminohydrolase; n=7; Rh... 39 0.16
UniRef50_Q0W553 Cluster: Putative acetoin utilization protein; n... 39 0.16
UniRef50_Q20296 Cluster: Histone deacetylase 6; n=4; Caenorhabdi... 39 0.16
UniRef50_Q8LRK8 Cluster: Histone deacetylase 18; n=1; Arabidopsi... 39 0.16
UniRef50_Q604Q2 Cluster: Histone deacetylase/AcuC/AphA family pr... 38 0.22
UniRef50_A5UTM3 Cluster: Histone deacetylase superfamily; n=4; B... 38 0.22
UniRef50_A5GUP9 Cluster: Histone deacetylase family protein; n=1... 38 0.22
UniRef50_Q2H2N4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.22
UniRef50_Q0G2C9 Cluster: Putative acetylpolyamine aminohydrolase... 38 0.29
UniRef50_Q8IJW3 Cluster: Putative uncharacterized protein; n=3; ... 38 0.29
UniRef50_A5K7A1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.29
UniRef50_UPI000065F55A Cluster: Histone deacetylase 7a (HD7a).; ... 38 0.38
UniRef50_Q63YT0 Cluster: Histone deacetylase family protein; n=1... 38 0.38
UniRef50_A6VSZ5 Cluster: Histone deacetylase superfamily; n=4; G... 38 0.38
UniRef50_A5UY48 Cluster: Histone deacetylase superfamily; n=4; C... 38 0.38
UniRef50_A0LFA3 Cluster: Histone deacetylase superfamily; n=3; D... 38 0.38
UniRef50_A0IVC2 Cluster: Histone deacetylase superfamily; n=5; P... 38 0.38
UniRef50_Q7R8P2 Cluster: Histone deacetylase family, putative; n... 38 0.38
UniRef50_Q4YUE6 Cluster: Putative uncharacterized protein; n=3; ... 38 0.38
UniRef50_A0DIS2 Cluster: Chromosome undetermined scaffold_52, wh... 38 0.38
UniRef50_A4QWC2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.38
UniRef50_O17323 Cluster: Histone deacetylase 4; n=3; Caenorhabdi... 38 0.38
UniRef50_Q586J9 Cluster: Histone deacetylase, putative; n=1; Try... 31 0.48
UniRef50_Q9U266 Cluster: Putative uncharacterized protein hda-6;... 37 0.50
UniRef50_A0C8R8 Cluster: Chromosome undetermined scaffold_159, w... 37 0.50
UniRef50_Q96DB2 Cluster: Histone deacetylase 11; n=22; Eumetazoa... 37 0.50
UniRef50_UPI000069F4DB Cluster: Histone deacetylase 7a (HD7a).; ... 37 0.66
UniRef50_Q6KAT4 Cluster: MFLJ00062 protein; n=6; Eutheria|Rep: M... 37 0.66
UniRef50_Q1PVG5 Cluster: Similar to histone deacetylase; n=1; Ca... 37 0.66
UniRef50_A4AX75 Cluster: Histone deacetylase/AcuC/AphA family pr... 37 0.66
UniRef50_Q8I9J6 Cluster: Histone deacetylase dHDAC4 isoform b; n... 37 0.66
UniRef50_A6GQW9 Cluster: Histone deacetylase family protein; n=1... 36 0.88
UniRef50_A3VQ74 Cluster: Probable histone deacetylase/AcuC/AphA ... 36 0.88
UniRef50_Q2QWU2 Cluster: Histone deacetylase family protein, exp... 36 0.88
UniRef50_A7SSG8 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 36 0.88
UniRef50_Q941D6 Cluster: Histone deacetylase 14; n=3; Spermatoph... 36 0.88
UniRef50_Q985Y7 Cluster: Mlr7469 protein; n=13; Alphaproteobacte... 36 1.2
UniRef50_Q30PJ4 Cluster: Histone deacetylase superfamily; n=1; T... 36 1.2
UniRef50_A3ZYN7 Cluster: Acetoin utilization protein; n=3; Planc... 36 1.2
UniRef50_A1G0Y5 Cluster: Histone deacetylase superfamily precurs... 36 1.2
UniRef50_A0G5H0 Cluster: Histone deacetylase superfamily; n=9; P... 36 1.2
UniRef50_Q4CZ55 Cluster: Histone deacetylase, putative; n=2; Try... 36 1.2
UniRef50_Q6CGA7 Cluster: Similar to sp|Q02959 Saccharomyces cere... 36 1.2
UniRef50_Q4W9N7 Cluster: Histone deacetylase HosB; n=3; Trichoco... 36 1.2
UniRef50_Q8WUI4 Cluster: Histone deacetylase 7a; n=41; Tetrapoda... 36 1.2
UniRef50_UPI000051A1DA Cluster: PREDICTED: similar to HDAC4 CG17... 36 1.5
UniRef50_Q9RW36 Cluster: Histone deacetylase/AcuC/AphA family pr... 36 1.5
UniRef50_Q02CA3 Cluster: Histone deacetylase superfamily; n=1; S... 36 1.5
UniRef50_A6LM84 Cluster: Histone deacetylase superfamily; n=1; T... 36 1.5
UniRef50_Q5AF34 Cluster: Likely histone deacetylase Hos3p; n=5; ... 36 1.5
UniRef50_Q1DM14 Cluster: Putative uncharacterized protein; n=1; ... 36 1.5
UniRef50_O28982 Cluster: Acetoin utilization protein, putative; ... 36 1.5
UniRef50_UPI0000D561E8 Cluster: PREDICTED: similar to CG1770-PA,... 35 2.0
UniRef50_Q17I08 Cluster: Histone deacetylase; n=1; Aedes aegypti... 35 2.0
UniRef50_A5E451 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0
UniRef50_A2R2F5 Cluster: Remark: N-terminal truncated orf due to... 35 2.0
UniRef50_A5UZV6 Cluster: Histone deacetylase superfamily; n=5; B... 35 2.7
UniRef50_A6RSL3 Cluster: Putative uncharacterized protein; n=2; ... 35 2.7
UniRef50_A2AWS5 Cluster: Histone deacetylase 5; n=21; Euarchonto... 34 3.5
UniRef50_Q128P1 Cluster: Histone deacetylase superfamily; n=16; ... 34 3.5
UniRef50_Q9UQL6 Cluster: Histone deacetylase 5; n=141; Eumetazoa... 34 3.5
UniRef50_Q987Q0 Cluster: Acetylpolyamine aminohydrolase; n=1; Me... 34 4.7
UniRef50_A5AUM3 Cluster: Putative uncharacterized protein; n=2; ... 34 4.7
UniRef50_Q8WZR5 Cluster: Related to histone deacetylase A; n=4; ... 34 4.7
UniRef50_O27994 Cluster: Acetylpolyamine aminohydrolase, putativ... 34 4.7
UniRef50_Q94EJ2 Cluster: Histone deacetylase 8; n=14; Magnolioph... 34 4.7
UniRef50_A6Q2Z0 Cluster: Acetoin utilization protein; n=1; Nitra... 33 6.2
UniRef50_A4BSQ6 Cluster: Histone deacetylase/AcuC/AphA family pr... 33 6.2
UniRef50_A0DV77 Cluster: Chromosome undetermined scaffold_65, wh... 33 6.2
UniRef50_Q7Z8L8 Cluster: Putative HOS3-like histone deacetylase;... 33 6.2
UniRef50_Q74MV2 Cluster: NEQ538; n=1; Nanoarchaeum equitans|Rep:... 33 6.2
>UniRef50_O15379 Cluster: Histone deacetylase 3; n=149;
Eukaryota|Rep: Histone deacetylase 3 - Homo sapiens
(Human)
Length = 428
Score = 313 bits (769), Expect = 3e-84
Identities = 134/169 (79%), Positives = 151/169 (89%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSE 459
VAYFY+PDVGNFHYG GHPMKPHRLA+TH LVL YGL+KKM ++KPY+AS HDMCRFHSE
Sbjct: 5 VAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSE 64
Query: 460 DYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD 639
DYI+FLQ V+P N+Q ++K L +NVGDDCPVF GLF+FCS YTGASL+GA +LNN CD
Sbjct: 65 DYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICD 124
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
IAINW+GGLHHAKKFE SGFCYVNDIVI ILELLKYHPRVLYIDID+HH
Sbjct: 125 IAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH 173
>UniRef50_UPI000065D235 Cluster: Histone deacetylase 1 (HD1).; n=1;
Takifugu rubripes|Rep: Histone deacetylase 1 (HD1). -
Takifugu rubripes
Length = 460
Score = 272 bits (666), Expect = 9e-72
Identities = 111/179 (62%), Positives = 149/179 (83%)
Frame = +1
Query: 250 ICLSTMTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRAS 429
+ LS T+++V Y+Y+ DVGN++YG GHPMKPHR+ +TH L+L YGL+++M+IY+P++AS
Sbjct: 1 MALSQGTKKKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRRMEIYRPHKAS 60
Query: 430 AHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEG 609
+M ++HS+DYI+FL+++ P N+ YSK + +NVG+DCPVF+GLF+FC + TG S+ G
Sbjct: 61 GEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAG 120
Query: 610 AMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
A+KLN DIAINW+GGLHHAKK E SGFCYVNDIV+AILELLKYH RVLYIDID+HH
Sbjct: 121 AVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH 179
>UniRef50_Q13547 Cluster: Histone deacetylase 1; n=60; Fungi/Metazoa
group|Rep: Histone deacetylase 1 - Homo sapiens (Human)
Length = 482
Score = 268 bits (658), Expect = 8e-71
Identities = 108/173 (62%), Positives = 146/173 (84%)
Frame = +1
Query: 268 TQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCR 447
T+++V Y+Y+ DVGN++YG GHPMKPHR+ +TH L+L YGL++KM+IY+P++A+A +M +
Sbjct: 7 TRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTK 66
Query: 448 FHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNN 627
+HS+DYI+FL+++ P N+ YSK + +NVG+DCPVF+GLF+FC + TG S+ A+KLN
Sbjct: 67 YHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNK 126
Query: 628 NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DIA+NW+GGLHHAKK E SGFCYVNDIV+AILELLKYH RVLYIDID+HH
Sbjct: 127 QQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH 179
>UniRef50_Q92769 Cluster: Histone deacetylase 2; n=50;
Eukaryota|Rep: Histone deacetylase 2 - Homo sapiens
(Human)
Length = 488
Score = 266 bits (651), Expect = 6e-70
Identities = 105/172 (61%), Positives = 146/172 (84%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
+++V Y+Y+ D+GN++YG GHPMKPHR+ +TH L+L YGL++KM+IY+P++A+A +M ++
Sbjct: 9 KKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKY 68
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
HS++YI+FL+++ P N+ YSK + +NVG+DCPVF+GLF+FC + TG S+ GA+KLN
Sbjct: 69 HSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQ 128
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
D+A+NW+GGLHHAKK E SGFCYVNDIV+AILELLKYH RVLYIDID+HH
Sbjct: 129 QTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH 180
>UniRef50_A2FDZ0 Cluster: Acetylpolyamine aminohydrolase, putative;
n=1; Trichomonas vaginalis G3|Rep: Acetylpolyamine
aminohydrolase, putative - Trichomonas vaginalis G3
Length = 453
Score = 236 bits (577), Expect = 5e-61
Identities = 95/175 (54%), Positives = 131/175 (74%)
Frame = +1
Query: 262 TMTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDM 441
++ ++R+AYFY+ D+GN++Y HPMKP R+ +TH LVL Y LH+ M ++ P RAS +M
Sbjct: 2 SIPKRRIAYFYDEDIGNYYYTHSHPMKPVRVRMTHSLVLGYKLHEHMDVFHPRRASPEEM 61
Query: 442 CRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKL 621
RFH+ YI+FLQ TP N S+D +HYN+G DCPVF+ +F+FC + G S+ A +L
Sbjct: 62 MRFHTPGYIKFLQTATPSNTNPKSEDAVHYNIGFDCPVFDNIFEFCQISAGGSISAAQRL 121
Query: 622 NNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
N N D+AINW+GGLHHA++ + SGFCY+ D V+ I+ELLKYHPRV+YIDID+HH
Sbjct: 122 NYNLADVAINWAGGLHHARRDQASGFCYIADCVLGIMELLKYHPRVMYIDIDIHH 176
>UniRef50_A3BWV6 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 384
Score = 234 bits (573), Expect = 2e-60
Identities = 98/172 (56%), Positives = 130/172 (75%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
++RV+YFY P +G+++YG GHPMKPHR+ + H LV+ YGLH+ +++ +PY AS D+ RF
Sbjct: 21 RRRVSYFYEPSIGDYYYGQGHPMKPHRIRMAHSLVVHYGLHRLLELSRPYPASDADIRRF 80
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
HS+DY+ FL + T ++ + +NVG+DCPVF+GLF FC G S+ A+KLN
Sbjct: 81 HSDDYVAFLASATGNPALLDARAVKRFNVGEDCPVFDGLFPFCQASAGGSIGAAVKLNRG 140
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DI +NW+GGLHHAKK E SGFCYVNDIV+AILELLK+H RVLY+DIDVHH
Sbjct: 141 DADITVNWAGGLHHAKKGEASGFCYVNDIVLAILELLKFHRRVLYVDIDVHH 192
>UniRef50_P53096 Cluster: Probable histone deacetylase HOS2; n=15;
Dikarya|Rep: Probable histone deacetylase HOS2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 452
Score = 231 bits (566), Expect = 1e-59
Identities = 99/171 (57%), Positives = 129/171 (75%), Gaps = 1/171 (0%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
RV+Y +N V ++HYG HPMKP RL +T LV YGLHK M +Y+ A+ ++ +FHS
Sbjct: 27 RVSYHFNSKVSHYHYGVKHPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHS 86
Query: 457 EDYIEFLQNVTPQNIQSYSKDLL-HYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
EDY+ FL V+P+N + L ++N+GDDCP+F+ L+D+ ++YTGASL+ KL NN
Sbjct: 87 EDYVNFLSKVSPENANKLPRGTLENFNIGDDCPIFQNLYDYTTLYTGASLDATRKLINNQ 146
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DIAINWSGGLHHAKK PSGFCYVNDIV++IL LL+YHPR+LYIDID+HH
Sbjct: 147 SDIAINWSGGLHHAKKNSPSGFCYVNDIVLSILNLLRYHPRILYIDIDLHH 197
>UniRef50_Q09440 Cluster: Putative histone deacetylase 2; n=2;
Caenorhabditis|Rep: Putative histone deacetylase 2 -
Caenorhabditis elegans
Length = 507
Score = 225 bits (549), Expect = 1e-57
Identities = 99/173 (57%), Positives = 129/173 (74%), Gaps = 1/173 (0%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
++ VAY+Y+ DVG+FHYG HPMKP RL V + LV+ Y + K M + + + A D+ F
Sbjct: 28 KRNVAYYYHKDVGHFHYGQLHPMKPQRLVVCNDLVVSYEMPKYMTVVESPKLDAADISVF 87
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLH-YNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNN 627
H+EDY+ FLQ VTP+ + D+L +N+G+DCP+F GL+D+C++Y G S+EGA +LN+
Sbjct: 88 HTEDYVNFLQTVTPKLGLTMPDDVLRQFNIGEDCPIFAGLWDYCTLYAGGSVEGARRLNH 147
Query: 628 NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DI INW GGLHHAKK E SGFCYVNDIV+ ILELLKYH RVLYIDID+HH
Sbjct: 148 KMNDIVINWPGGLHHAKKSEASGFCYVNDIVLGILELLKYHKRVLYIDIDIHH 200
>UniRef50_Q5U8M9 Cluster: Histone deacetylase 1; n=2; Entamoeba
histolytica|Rep: Histone deacetylase 1 - Entamoeba
histolytica
Length = 448
Score = 221 bits (541), Expect = 1e-56
Identities = 100/172 (58%), Positives = 124/172 (72%), Gaps = 2/172 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
RV YFY+ +VG F YG GHPMKP R + H L+++YG++K++ IYKP+RA+ M FHS
Sbjct: 3 RVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKPWRATNEQMEMFHS 62
Query: 457 EDYIEFLQNVTPQNIQS--YSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
++YI+FLQ VTP+ + K L +N DDCPVFEGL+ F G+SL AMK+N
Sbjct: 63 KEYIDFLQRVTPEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINER 122
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DI +NWSGGLHHAKK + SGFCY+NDIV AILELLK H RVLYIDID HH
Sbjct: 123 AADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHH 174
>UniRef50_Q4WHY0 Cluster: Histone deacetylase HosA; n=15;
Fungi/Metazoa group|Rep: Histone deacetylase HosA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 487
Score = 217 bits (529), Expect = 3e-55
Identities = 92/172 (53%), Positives = 126/172 (73%), Gaps = 2/172 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
RV++ NP V H+G HPMKP RL +T LV+ YG+H M +Y A+ +M FH
Sbjct: 42 RVSWHANPAVEPHHFGQSHPMKPWRLTLTKQLVMAYGMHHAMDLYLARAATYEEMAEFHQ 101
Query: 457 EDYIEFLQNVTPQNIQS--YSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
DY++FL+ V P ++++ S+++ +N GDDCP+F GL+++CS+Y G S++ A KL NN
Sbjct: 102 TDYLDFLRQVMPGDMENPEQSENIARFNFGDDCPIFNGLYNYCSLYAGGSIDAARKLCNN 161
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+IA+NWSGGLHHAKK E SGFCYVNDIV+ IL+LL++HPRV+YIDIDVHH
Sbjct: 162 QSEIAVNWSGGLHHAKKAEASGFCYVNDIVLGILQLLRHHPRVMYIDIDVHH 213
>UniRef50_Q5KKR8 Cluster: Histone deacetylase 1-1 (Hd1), putative;
n=3; Filobasidiella neoformans|Rep: Histone deacetylase
1-1 (Hd1), putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 659
Score = 168 bits (408), Expect(2) = 2e-54
Identities = 75/131 (57%), Positives = 96/131 (73%)
Frame = +1
Query: 394 KKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFD 573
K+MQI++P RA+ DM RFH+++YIE L++V P+N + + + G DCP EG+F+
Sbjct: 97 KRMQIFRPRRATKTDMTRFHTDEYIELLESVLPENADALTGNRSRGLTGSDCPAVEGIFE 156
Query: 574 FCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP 753
F S+ G S+ A KLN DIAINW+GGLHHAKK E SGFCYVNDIV+ ILELL+ +
Sbjct: 157 FSSISAGGSIGAAEKLNEGIADIAINWAGGLHHAKKTEASGFCYVNDIVLGILELLRVNS 216
Query: 754 RVLYIDIDVHH 786
RVLYIDIDVHH
Sbjct: 217 RVLYIDIDVHH 227
Score = 67.7 bits (158), Expect(2) = 2e-54
Identities = 26/39 (66%), Positives = 34/39 (87%)
Frame = +1
Query: 274 QRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGL 390
+RVAY+Y+ DVGN+H+G GHPMKPHR+ +TH LV+ YGL
Sbjct: 20 RRVAYYYDHDVGNYHFGLGHPMKPHRIRMTHNLVVNYGL 58
>UniRef50_Q9HDT2 Cluster: Histone deacetylase; n=4; Fungi/Metazoa
group|Rep: Histone deacetylase - Ustilago maydis (Smut
fungus)
Length = 566
Score = 212 bits (517), Expect = 1e-53
Identities = 89/151 (58%), Positives = 115/151 (76%)
Frame = +1
Query: 334 PMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYS 513
PMKPHR+ +TH LV YGLHKKM I +P RA+ M RFH+++Y++FL VTP+ + +
Sbjct: 13 PMKPHRMRMTHNLVTNYGLHKKMDILRPKRATRDQMTRFHTDEYVDFLHRVTPETVHELT 72
Query: 514 KDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPS 693
+ Y +G+DCP F+GL++FCS+ G SL A +LN+ D+AINW+GGLHHAKK E S
Sbjct: 73 NEGTRYLIGEDCPAFDGLYEFCSISAGGSLAAATRLNSGESDVAINWAGGLHHAKKREAS 132
Query: 694 GFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
GFCYVNDIV+AILELL+ H RVLYIDID+HH
Sbjct: 133 GFCYVNDIVLAILELLRVHLRVLYIDIDIHH 163
>UniRef50_Q5XTS3 Cluster: Histone deacetylase HDAC; n=2; Giardia
intestinalis|Rep: Histone deacetylase HDAC - Giardia
lamblia (Giardia intestinalis)
Length = 467
Score = 207 bits (506), Expect = 2e-52
Identities = 86/173 (49%), Positives = 117/173 (67%)
Frame = +1
Query: 265 MTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMC 444
M + ++FYNP F++G HPMKP R+A+ + L+L YGL + + Y P A+ DM
Sbjct: 1 MPPSKPSFFYNPLFPTFYFGLHHPMKPFRIALVNELILAYGLDEHLNYYTPRDATFQDMA 60
Query: 445 RFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLN 624
+H+ DYI FL+N+TP+ + + YN+ +DCPVF GL+D+CSM GAS+ LN
Sbjct: 61 LYHTPDYIRFLKNITPETLSKFQDLAKRYNITEDCPVFSGLYDYCSMTVGASVNACAHLN 120
Query: 625 NNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVH 783
+ CD+A+NW GG HHAK E SGFCY ND+V+ ILELLK H RVLY+DID+H
Sbjct: 121 HGMCDVALNWMGGFHHAKASEASGFCYANDLVLGILELLKVHERVLYVDIDIH 173
>UniRef50_Q0V6A5 Cluster: Putative uncharacterized protein; n=2;
Pleosporales|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 507
Score = 198 bits (484), Expect = 1e-49
Identities = 93/172 (54%), Positives = 115/172 (66%), Gaps = 3/172 (1%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSE 459
V++ YNP V H+G HPMKP RL +T LV+ YGL M +Y P A+ ++ FH
Sbjct: 63 VSFHYNPHVEYHHFGSSHPMKPWRLTLTKQLVVAYGLEYTMDLYTPRPANFGELALFHDR 122
Query: 460 DYIEFLQNVTPQNIQSYSKDLLHYNVG---DDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
+Y+E+L +TPQN Q + Y G +DCPVF+GL+++ S+Y+GAS+ A L N
Sbjct: 123 EYLEYLSKITPQNAQPEDPQYISYGFGGDSNDCPVFDGLWNYVSLYSGASMSAAWNLLNK 182
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DIAINWSGGLHHAKK SGFCYVNDIVIAI LL H RVLYIDIDVHH
Sbjct: 183 QSDIAINWSGGLHHAKKNLASGFCYVNDIVIAIQLLLTQHQRVLYIDIDVHH 234
>UniRef50_A4RK28 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 466
Score = 194 bits (472), Expect = 3e-48
Identities = 93/201 (46%), Positives = 129/201 (64%), Gaps = 6/201 (2%)
Frame = +1
Query: 202 SDSCHFEYYFCVERIRICLSTMTQQ--RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLV 375
SD+ + +Y ++R+ + + V++ NP++ H+G HPMKP RL ++ L+
Sbjct: 38 SDADNAAFYNKIKRVAETYNITRPKGHNVSFHVNPEMEKHHFGQTHPMKPWRLTLSKALI 97
Query: 376 LKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQ----NIQSYSKDLLHYNVGD 543
YG++ M Y A+ ++ FH+ DYI+FL V P+ ++ + DL G
Sbjct: 98 SSYGMNFAMDNYVSRAATYDELTMFHASDYIQFLGTVLPEPIPRDVDNPYPDLKFNLGGS 157
Query: 544 DCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVI 723
DCP+FEGL+D+CSM G SL+ A K+ NN DIAI W GGLHHAK+ E SGFCY+NDIVI
Sbjct: 158 DCPLFEGLYDYCSMSAGGSLDAARKICNNQSDIAIAWGGGLHHAKRSEASGFCYINDIVI 217
Query: 724 AILELLKYHPRVLYIDIDVHH 786
AIL+LL+ HPRVLYIDIDVHH
Sbjct: 218 AILQLLRCHPRVLYIDIDVHH 238
>UniRef50_A4VDD9 Cluster: Histone deacetylase 1, 2 ,3; n=4;
Oligohymenophorea|Rep: Histone deacetylase 1, 2 ,3 -
Tetrahymena thermophila SB210
Length = 473
Score = 180 bits (438), Expect = 4e-44
Identities = 91/194 (46%), Positives = 122/194 (62%), Gaps = 21/194 (10%)
Frame = +1
Query: 268 TQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCR 447
T+++VAYFYN ++GN++YG H M P R+++TH L++ YG++K + +Y A+ ++ +
Sbjct: 3 TKKKVAYFYNNEIGNYNYGKLHLMNPKRISMTHSLIVGYGVYKDLDVYTTREATKEEIMQ 62
Query: 448 FHSEDYIEFLQN-VTPQNIQ-------------------SYSKDLLHYNVGDDCPVFEGL 567
FH +DY+E+L N V+ I S K +V DCP F+GL
Sbjct: 63 FHDQDYVEYLSNYVSSSKIDFLKKNGCSIPLIDEDAKNDSDKKKQYGIDVQADCPGFDGL 122
Query: 568 FDFCSMYTGA-SLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLK 744
+ F + TG S++ A + NN DIAINW GGLHHAKK E GFCYVNDIVI ILELLK
Sbjct: 123 YTFSQLSTGGGSIDAAHLIINNAADIAINWGGGLHHAKKGEAYGFCYVNDIVICILELLK 182
Query: 745 YHPRVLYIDIDVHH 786
PRVLYIDIDVHH
Sbjct: 183 VFPRVLYIDIDVHH 196
>UniRef50_A0DPM0 Cluster: Chromosome undetermined scaffold_59, whole
genome shotgun sequence; n=7; Eukaryota|Rep: Chromosome
undetermined scaffold_59, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 443
Score = 175 bits (425), Expect = 1e-42
Identities = 83/179 (46%), Positives = 114/179 (63%), Gaps = 7/179 (3%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQ-----IYKPY--RAS 429
+Q+V Y+Y+ + G ++Y HPMKP R+A+T LV YGL + M + Y R
Sbjct: 24 KQKVTYYYDEEFGTYNYSTTHPMKPLRVAITDDLVGHYGLKQYMNCIDQSFVQTYIKRVD 83
Query: 430 AHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEG 609
+ +FHS +YI+ ++ +TP+N Y L +N +DCPV + LFDFC T S+
Sbjct: 84 EDVLTQFHSYEYIDLIKIITPENKCQYEDQLYRFNFMEDCPVLDRLFDFCLCQTSGSVGA 143
Query: 610 AMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
A + + +IAINWSGGLHHAK+ E SGFCYVND V+ ILELLK + RVLY+DID+HH
Sbjct: 144 ACVIADQKSNIAINWSGGLHHAKQSEASGFCYVNDCVLGILELLKTYQRVLYVDIDIHH 202
>UniRef50_Q8SQN9 Cluster: HISTONE DEACETYLASE; n=1; Encephalitozoon
cuniculi|Rep: HISTONE DEACETYLASE - Encephalitozoon
cuniculi
Length = 344
Score = 165 bits (402), Expect = 8e-40
Identities = 88/170 (51%), Positives = 105/170 (61%), Gaps = 1/170 (0%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSE 459
VAY ++ +VG FHYGP HPMKP R VTH LV +GL KKM I KP + +H+E
Sbjct: 3 VAYMFDEEVGLFHYGPRHPMKPFRTVVTHSLVKSFGLDKKMTIVKP---EVFPLSSYHTE 59
Query: 460 DYIEFL-QNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC 636
+Y+ L +N TP DCP F GL FC +Y AS+ AM L+
Sbjct: 60 EYLGNLGKNETP-----------------DCPNFIGLPRFCELYGSASINSAMILSEGAY 102
Query: 637 DIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
INWSGGLHHA K PSGFC+VNDIV+AILELLK + RV+YIDIDVHH
Sbjct: 103 STVINWSGGLHHAHKAIPSGFCHVNDIVLAILELLKTYRRVMYIDIDVHH 152
>UniRef50_Q94D35 Cluster: Histone deacetylase-like; n=9; Oryza
sativa|Rep: Histone deacetylase-like - Oryza sativa
subsp. japonica (Rice)
Length = 481
Score = 161 bits (390), Expect = 2e-38
Identities = 82/185 (44%), Positives = 111/185 (60%), Gaps = 13/185 (7%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
++RV Y+Y+P + YG GH M PHR+ + H LV YG+ M+ + A+A ++ F
Sbjct: 19 KRRVCYYYDPGISTVDYGEGHVMVPHRVTMAHNLVAAYGMLGDMRRLRTAPATAAELADF 78
Query: 451 HSEDYIEFLQNVTPQN------IQSYSKDLLHYNV-------GDDCPVFEGLFDFCSMYT 591
H E Y+ LQ++TP + ++ Y V G D PVF+ L+D+C Y+
Sbjct: 79 HDEGYLALLQDLTPDGCGGDDGVGDMARARGIYAVEGKGGGRGVDNPVFDRLWDYCLRYS 138
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYID 771
G SL A L + T DIAINWSGG+HHA + GFCYVNDIV+AI ELL + RVLY+D
Sbjct: 139 GGSLAAARTLGSGTADIAINWSGGMHHACRGGARGFCYVNDIVLAIRELLAHFRRVLYVD 198
Query: 772 IDVHH 786
IDVHH
Sbjct: 199 IDVHH 203
>UniRef50_A0CXG2 Cluster: Chromosome undetermined scaffold_30, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_30,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 482
Score = 159 bits (385), Expect = 1e-37
Identities = 88/209 (42%), Positives = 122/209 (58%), Gaps = 36/209 (17%)
Frame = +1
Query: 268 TQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYG-LHKKMQIYKPYRASAHDMC 444
+ +RVAYFYN +G FHYG HPMKP R+A+ H L++ +G L++ + +Y A ++
Sbjct: 8 SSRRVAYFYNRLIGKFHYGKEHPMKPKRIAMAHSLIVNFGQLYRSLDVYLIREAQLEELQ 67
Query: 445 RFHSEDY------------IEFLQN--------VTPQNI-QSY-----------SKDL-L 525
+FH +Y + F++ V P+N+ + Y +K+L
Sbjct: 68 KFHDPEYVTYLSQYMSENKVNFVKEYCSTNNDGVIPENLLEEYRLITKWSQNKNTKNLNS 127
Query: 526 HYNVGD--DCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGF 699
Y VGD D P F GLF +C GAS++ A + DIAINWSGGLHHAKK E +GF
Sbjct: 128 EYKVGDSADNPTFSGLFSYCQFSAGASIDCAHTILTGQADIAINWSGGLHHAKKKEAAGF 187
Query: 700 CYVNDIVIAILELLKYHPRVLYIDIDVHH 786
CY+NDIV+ ILELL+ + RVLY+DID HH
Sbjct: 188 CYINDIVLCILELLRIYVRVLYVDIDCHH 216
>UniRef50_A0PAD5 Cluster: Putative uncharacterized protein; n=2;
Ipomoea trifida|Rep: Putative uncharacterized protein -
Ipomoea trifida (Morning glory)
Length = 496
Score = 156 bits (379), Expect = 5e-37
Identities = 63/97 (64%), Positives = 81/97 (83%)
Frame = +1
Query: 496 NIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHA 675
+++S +D YN+G+DCPVF+ LF+FC +Y G +++ A +LNN CD+AINW+GGLHHA
Sbjct: 94 SLRSPQQDGNLYNLGEDCPVFDNLFEFCQIYAGGTIDAARRLNNQLCDVAINWAGGLHHA 153
Query: 676 KKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
KK E SGFCY+ND+V+ ILELLKYHPRVLYIDIDVHH
Sbjct: 154 KKCEASGFCYINDLVLGILELLKYHPRVLYIDIDVHH 190
>UniRef50_Q9BY41 Cluster: Histone deacetylase 8; n=40;
Eumetazoa|Rep: Histone deacetylase 8 - Homo sapiens
(Human)
Length = 377
Score = 153 bits (371), Expect = 5e-36
Identities = 67/148 (45%), Positives = 96/148 (64%)
Frame = +1
Query: 343 PHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDL 522
P R ++ H L+ Y LHK+M+I KP AS +M FH++ Y++ LQ V+ + + D
Sbjct: 35 PKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHP-DS 93
Query: 523 LHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFC 702
+ Y +G DCP EG+FD+ + GA++ A L + C +AINWSGG HHAKK E SGFC
Sbjct: 94 IEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFC 153
Query: 703 YVNDIVIAILELLKYHPRVLYIDIDVHH 786
Y+ND V+ IL L + R+LY+D+D+HH
Sbjct: 154 YLNDAVLGILRLRRKFERILYVDLDLHH 181
>UniRef50_Q98RL4 Cluster: Histone deacetylase; n=1; Guillardia
theta|Rep: Histone deacetylase - Guillardia theta
(Cryptomonas phi)
Length = 374
Score = 152 bits (369), Expect = 8e-36
Identities = 76/174 (43%), Positives = 108/174 (62%)
Frame = +1
Query: 265 MTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMC 444
MTQ++ N +GNF Y HPM+P RL++T L+ YG+ K ++I + + + +M
Sbjct: 1 MTQKKTVLAENSKIGNFAYSRFHPMQPIRLSMTSELIYSYGMEKFLRIIRTEKKTNSEMF 60
Query: 445 RFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLN 624
HS + EF + +N +S + + DCP+F+GL ++ +Y+ ASL +L
Sbjct: 61 NIHSSIF-EF-NVIKKKNFESINYITID-KYDADCPIFKGLNEYLLLYSSASLLSLDELT 117
Query: 625 NNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
NN C IAINWSGGLHH+K E SGFCY+NDI + IL LLK+ +LYIDIDVHH
Sbjct: 118 NNNCQIAINWSGGLHHSKIDEKSGFCYLNDINLCILNLLKHFNYILYIDIDVHH 171
>UniRef50_UPI0000587266 Cluster: PREDICTED: similar to Histone
deacetylase 8; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Histone deacetylase 8 -
Strongylocentrotus purpuratus
Length = 654
Score = 134 bits (325), Expect = 2e-30
Identities = 64/152 (42%), Positives = 93/152 (61%), Gaps = 1/152 (0%)
Frame = +1
Query: 334 PMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYS 513
P P R ++ H L+ Y L + P A+ ++ FHS++YIEFL+ V +
Sbjct: 307 PKIPKRASMVHTLIEAYDLLDHVTPVSPEFATKDELLTFHSQEYIEFLERVNLEEDSEKD 366
Query: 514 KDLLH-YNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEP 690
++L + +G DCP ++DF + GASL A L C IAINW+GG HHA++ E
Sbjct: 367 EELKQQFGLGYDCPSLPLVYDFVRLVAGASLSCAKALIQQKCRIAINWNGGWHHARRDEA 426
Query: 691 SGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+GFCYVNDIV+AIL+L ++ RVLY+D+D+HH
Sbjct: 427 AGFCYVNDIVLAILKLKEHFNRVLYVDLDLHH 458
>UniRef50_O88895-2 Cluster: Isoform Short of O88895 ; n=6;
Euteleostomi|Rep: Isoform Short of O88895 - Mus musculus
(Mouse)
Length = 233
Score = 128 bits (308), Expect = 2e-28
Identities = 53/66 (80%), Positives = 60/66 (90%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSE 459
VAYFY+PDVGNFHYG GHPMKPHRLA+TH LVL YGL+KKM ++KPY+AS HDMCRFHSE
Sbjct: 5 VAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSE 64
Query: 460 DYIEFL 477
DYI+ L
Sbjct: 65 DYIDSL 70
>UniRef50_A3C9I4 Cluster: Putative uncharacterized protein; n=6;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 449
Score = 128 bits (308), Expect = 2e-28
Identities = 63/149 (42%), Positives = 91/149 (61%), Gaps = 6/149 (4%)
Frame = +1
Query: 358 VTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQN------IQSYSKD 519
+ H LV YG+ M + A+ ++ RFHS +Y++ L+++TP++ ++ ++D
Sbjct: 1 MAHSLVGVYGMLGDMSRLRTRPATEAEIRRFHSPEYVDLLRDLTPESYFNDAALRQKAED 60
Query: 520 LLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGF 699
DDCP F+ L+ +C Y G SL A L + DIAINWSGG+HHA + +GF
Sbjct: 61 DHGIGGKDDCPAFDRLWKYCRGYAGGSLAAARALVDGASDIAINWSGGMHHASACKATGF 120
Query: 700 CYVNDIVIAILELLKYHPRVLYIDIDVHH 786
CYVNDIV+AI ELL RV+Y+DID HH
Sbjct: 121 CYVNDIVLAINELLGTFRRVIYVDIDAHH 149
>UniRef50_Q4QAJ4 Cluster: Histone deacetylase, putative; n=3;
Leishmania|Rep: Histone deacetylase, putative -
Leishmania major
Length = 536
Score = 121 bits (292), Expect = 2e-26
Identities = 68/182 (37%), Positives = 96/182 (52%), Gaps = 11/182 (6%)
Frame = +1
Query: 274 QRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKK--MQIYKPYRASAHDMCR 447
++V YF + V Y GH M+P R+ H LV GL M + A+A +M
Sbjct: 83 RKVLYFVDHSVTAIAYAEGHLMRPSRVRALHALVHSLGLDNAECMTVCHARPATAEEMGA 142
Query: 448 FHSEDYIEFLQ-------NVTPQNIQSYSK--DLLHYNVGDDCPVFEGLFDFCSMYTGAS 600
FH Y+E L+ N + ++ K D+ + DCP+F ++ S GAS
Sbjct: 143 FHRSAYLECLRQAPVICGNPLDEMSLAFQKEFDVPFASQDSDCPLFPEVWALVSSQAGAS 202
Query: 601 LEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDV 780
L A L +A+NW+GG+HHA SGFC+VNDIV+ I LL+Y+ RVLY+D+DV
Sbjct: 203 LACAEALVRGDATVAMNWAGGMHHAAAAHASGFCFVNDIVLCIRRLLRYYQRVLYVDLDV 262
Query: 781 HH 786
HH
Sbjct: 263 HH 264
>UniRef50_Q4QCE7 Cluster: Histone deacetylase, putative; n=7;
Trypanosomatidae|Rep: Histone deacetylase, putative -
Leishmania major
Length = 428
Score = 118 bits (285), Expect = 1e-25
Identities = 61/167 (36%), Positives = 91/167 (54%), Gaps = 2/167 (1%)
Frame = +1
Query: 292 YNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIE 471
Y D+ + P H MKP+R+ +V + + P ++ +H++ Y
Sbjct: 30 YASDMNISAFVPQHAMKPYRVLAAMEIVRSLKIDAHCRTVVPPLVKVEELMAYHTDTY-- 87
Query: 472 FLQNVTPQNIQSY--SKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIA 645
L N+ + +S+ + + DCP EGL + +L GA+ LN+ D+A
Sbjct: 88 -LANLGLHSCRSWLWNAETSKVFFSGDCPPVEGLMEHSIATASGTLMGAVLLNSGQVDVA 146
Query: 646 INWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
++W GG+HH+K E SGFCYVNDIV+ ILELLK H RVLY+DID+HH
Sbjct: 147 VHWGGGMHHSKCGECSGFCYVNDIVLGILELLKCHDRVLYVDIDMHH 193
>UniRef50_Q17CU3 Cluster: Histone deacetylase; n=2; Aedes
aegypti|Rep: Histone deacetylase - Aedes aegypti
(Yellowfever mosquito)
Length = 355
Score = 118 bits (283), Expect = 2e-25
Identities = 58/148 (39%), Positives = 87/148 (58%), Gaps = 1/148 (0%)
Frame = +1
Query: 346 HRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQN-IQSYSKDL 522
+R AV LV Y L + ++ P R + D+ FHS DY+E L+ ++ I+ + +L
Sbjct: 9 NRSAVVDELVRSYDLLQFCKVISPKRGTLEDLLSFHSSDYVECLKRYNNEDDIEEVTDEL 68
Query: 523 LHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFC 702
+ + DCP+ E ++DF S G++L + IAINW GG HHA++ + +GFC
Sbjct: 69 QEFGLAYDCPMIEKVYDFVSSVVGSTLSAVDAILEGA-SIAINWHGGWHHAQRDKAAGFC 127
Query: 703 YVNDIVIAILELLKYHPRVLYIDIDVHH 786
YVNDIVI I +L +VLY+D+DVHH
Sbjct: 128 YVNDIVIGIHKLRTKFQKVLYLDLDVHH 155
>UniRef50_Q74DU3 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=7; Desulfuromonadales|Rep: Histone
deacetylase/AcuC/AphA family protein - Geobacter
sulfurreducens
Length = 385
Score = 113 bits (273), Expect = 4e-24
Identities = 64/173 (36%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHK--KMQIYKPYRASAHDMCRF 450
R A Y+ D F YG HP K R + L+ YGL + ++I RA+ + F
Sbjct: 4 RTALIYSNDFARFSYGDDHPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEALLTF 63
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGD-DCPVFEGLFDFCSMYTGASLEGAMKLNN 627
H+ DY++ L+ + + ++ Y +GD D PVF GL+D+ + G ++E A +
Sbjct: 64 HAPDYLDRLREFSESDD---ARADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAE 120
Query: 628 NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
DIA N +GG HHA + + SGF Y+ND V+AI LL+ RV Y+DID HH
Sbjct: 121 EGYDIAFNLAGGWHHAHRAKASGFSYLNDAVVAINLLLEKGLRVAYLDIDAHH 173
>UniRef50_A0B926 Cluster: Histone deacetylase superfamily; n=1;
Methanosaeta thermophila PT|Rep: Histone deacetylase
superfamily - Methanosaeta thermophila (strain DSM 6194
/ PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 370
Score = 111 bits (267), Expect = 2e-23
Identities = 60/170 (35%), Positives = 90/170 (52%), Gaps = 3/170 (1%)
Frame = +1
Query: 286 YFYNPDVG-NFHYGPGHPMKPHRLAVTHCLVLKYG--LHKKMQIYKPYRASAHDMCRFHS 456
Y Y D+ + +GP HP++P R+ +T+ ++ +YG L ++ PY AS D+ H
Sbjct: 3 YLYYTDMFMGYSFGPEHPLQPARIMLTYRMIEEYGFFLGYDTEVQMPYYASEDDLLMVHD 62
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC 636
YI+ ++ P + D PVF G++D ++ GAS+E A ++ + C
Sbjct: 63 PGYIQAVKEERPDPALGLDEP--------DTPVFPGIYDASALIAGASIEAAKRVASEPC 114
Query: 637 DIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+A N +GGLHHA +GFC ND + I L K RVLYIDID HH
Sbjct: 115 -VAFNLAGGLHHAFPARAAGFCVFNDCALGIRTLRKRFDRVLYIDIDAHH 163
>UniRef50_UPI0000D55D9C Cluster: PREDICTED: similar to histone
deacetylase 8; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to histone deacetylase 8 - Tribolium castaneum
Length = 376
Score = 110 bits (265), Expect = 3e-23
Identities = 53/154 (34%), Positives = 84/154 (54%), Gaps = 3/154 (1%)
Frame = +1
Query: 334 PMKPHRLAVTHCLVLKYGL--HKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTP-QNIQ 504
P +R ++ L+ Y + K+ + A+ ++ FHS YI FL+ V N +
Sbjct: 23 PTMLNRASIVQDLINSYRILCSDKVLTVQSRDATEDELKLFHSSSYINFLKKVNNLDNFE 82
Query: 505 SYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKF 684
Y ++ + +G DCP+ E +DF G S+ A L + INW GG HHA++
Sbjct: 83 DYDEEQQEFGLGYDCPILEHNYDFIKTIAGGSITAAKILCKTDYKVVINWFGGWHHAQRD 142
Query: 685 EPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+GFCYVNDIV+AI +L + ++LY+D+D+HH
Sbjct: 143 SAAGFCYVNDIVLAIQKLTEKFTKILYLDLDIHH 176
>UniRef50_Q6C3Y5 Cluster: Similar to CA1453|CaHOS1 Candida albicans
CaHOS1 Putative histone deacetylase; n=1; Yarrowia
lipolytica|Rep: Similar to CA1453|CaHOS1 Candida
albicans CaHOS1 Putative histone deacetylase - Yarrowia
lipolytica (Candida lipolytica)
Length = 424
Score = 108 bits (260), Expect = 1e-22
Identities = 52/153 (33%), Positives = 83/153 (54%)
Frame = +1
Query: 328 GHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQS 507
G P R A+ L++ LHK ++ A+A ++ R+HS +Y+ +
Sbjct: 63 GRPSNEGRAALVDSLLVALQLHKSYKLIPITPATAAELQRYHSLEYVSAVLKKGQSEKTL 122
Query: 508 YSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFE 687
L+H DCP+F GL + + G++L A +L + + INW GG HH K+
Sbjct: 123 DKMGLIH-----DCPIFPGLDAYVKLVAGSTLSCARQLMSGQHQLCINWYGGRHHGKRSA 177
Query: 688 PSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
SGFCYVND+V+ I E+ K + +++YID+D+HH
Sbjct: 178 ASGFCYVNDVVLGIQEMRKQYQKIMYIDVDLHH 210
>UniRef50_Q3A415 Cluster: Deacetylase; n=1; Pelobacter carbinolicus
DSM 2380|Rep: Deacetylase - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 381
Score = 107 bits (257), Expect = 3e-22
Identities = 58/171 (33%), Positives = 93/171 (54%), Gaps = 3/171 (1%)
Frame = +1
Query: 283 AYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKK--MQIYKPYRASAHDMCRFHS 456
A+ Y+ G +G GHP K R A+T+ L+ L + +++ + RA+ ++ FH
Sbjct: 6 AFIYSSRFGQGVFGQGHPFKVERFALTYALLDALHLLSRPGIRLIEAPRATYAELLSFHH 65
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGD-DCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
DY+ LQ + S + + +GD + PVFE LFD+ S+ G ++E A ++ +
Sbjct: 66 PDYLRTLQEFS---CDSTRRADFRFGLGDMENPVFEDLFDWVSLCCGGTMEAARQVLDKN 122
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
C A N +GG HHA SGF Y+ND V+AI ++ +V Y+D+D HH
Sbjct: 123 CRCAFNMAGGWHHAHAARASGFSYLNDAVVAINSMVARGFKVAYVDLDAHH 173
>UniRef50_Q0S1K3 Cluster: Possible acetoin dehydrogenase; n=3;
Bacteria|Rep: Possible acetoin dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 423
Score = 97.9 bits (233), Expect = 3e-19
Identities = 54/170 (31%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Frame = +1
Query: 283 AYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSED 462
A ++PD ++ + HPM P RL +T L G+ + +++ +P AS D+ R H+
Sbjct: 19 AVVWSPDYLSYRWSADHPMNPTRLELTMSLARSLGILEGVELLRPAAASDADLLRIHTPA 78
Query: 463 YIEFLQNVTPQNIQSY-SKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD 639
Y+E ++ D H +D PVF + + ++ G SL A ++
Sbjct: 79 YVEAVKQAGHSATSGVLGADAPHGLGTEDNPVFPQMHEASAILAGGSLAAAQEIAAGRTR 138
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKY-HPRVLYIDIDVHH 786
A++ GG+HHA SGFC ND+ IAI LL + R+ YID+D HH
Sbjct: 139 RAVSIGGGMHHAMPDWASGFCVYNDVAIAISWLLDHGFDRIAYIDVDAHH 188
>UniRef50_UPI000050FC36 Cluster: COG0123: Deacetylases, including
yeast histone deacetylase and acetoin utilization
protein; n=1; Brevibacterium linens BL2|Rep: COG0123:
Deacetylases, including yeast histone deacetylase and
acetoin utilization protein - Brevibacterium linens BL2
Length = 401
Score = 95.5 bits (227), Expect = 1e-18
Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 4/178 (2%)
Frame = +1
Query: 265 MTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHK--KMQIYKPYRASAHD 438
M V ++ V +++GP HPM P RL +T L + +GL + ++
Sbjct: 4 MADSDVYVVWDDAVTGYNFGPSHPMHPLRLDLTATLAMDFGLFDADNVHVHGVSDVEEDT 63
Query: 439 MCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVG-DDCPVFEGLFDFCSMYTGASLEGAM 615
+ + H D+I ++ + + S +D Y +G +D P FE + +M S++ A
Sbjct: 64 LAKLHDADFIAAVKQIGDGAVLS-DEDARKYGIGTEDVPGFENMHAASAMLFQGSVDSAR 122
Query: 616 KLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELL-KYHPRVLYIDIDVHH 786
+ + A+N++GG+HHA SGFC NDI AI E L + R+ YID+D HH
Sbjct: 123 AIISGDYSHAVNFTGGMHHAMPDHASGFCVYNDIAGAITEFLGAGYERIAYIDLDAHH 180
>UniRef50_A0K0A0 Cluster: Histone deacetylase superfamily; n=2;
Arthrobacter|Rep: Histone deacetylase superfamily -
Arthrobacter sp. (strain FB24)
Length = 407
Score = 92.7 bits (220), Expect = 1e-17
Identities = 53/161 (32%), Positives = 82/161 (50%), Gaps = 3/161 (1%)
Frame = +1
Query: 313 FHYGPGHPMKPHRLAVTHCLVLKYGLHK--KMQIYKPYRASAHDMCRFHSEDYIEFLQNV 486
+++G GHPM P R+ +T L GL + + P A ++C HS +++ ++ V
Sbjct: 25 YNFGHGHPMAPERMELTARLARSLGLLDLGHVTVAAPEVAGDDELCTVHSAEFVAAVRRV 84
Query: 487 TPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGL 666
+ + DL +D P F G+ + + G SL A + + + A+N+ GG+
Sbjct: 85 S---LNPDEPDLERGLGTEDDPAFAGMHEASARLAGGSLMAASAILDGSAVRAVNFGGGM 141
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH-PRVLYIDIDVHH 786
HHA K SGFC ND +AI +LL RV YID+D HH
Sbjct: 142 HHAAKERASGFCIYNDAALAIQKLLDGGLQRVAYIDVDAHH 182
>UniRef50_A5H660 Cluster: Histone deacetylase 8; n=3;
Schistosoma|Rep: Histone deacetylase 8 - Schistosoma
mansoni (Blood fluke)
Length = 440
Score = 91.5 bits (217), Expect = 2e-17
Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 15/128 (11%)
Frame = +1
Query: 448 FHSEDYIEFLQNVTPQNIQ----SYSKDLL--HYNVGDDCPVFEGLFDFCSMYTGASLEG 609
FHS +Y++ L+ + + + + +LL +++ DCP F +FD+ SL
Sbjct: 62 FHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYDCPGFPSVFDYSLAAVQGSLAA 121
Query: 610 AMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP---------RVL 762
A L C++ INW GG HHAK+ E SGFCY+NDIV+AI L+ P RVL
Sbjct: 122 ASALICRHCEVVINWGGGWHHAKRSEASGFCYLNDIVLAIHRLVSSTPPETSPNRQTRVL 181
Query: 763 YIDIDVHH 786
Y+D+D+HH
Sbjct: 182 YVDLDLHH 189
>UniRef50_A5DN16 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 385
Score = 90.2 bits (214), Expect = 5e-17
Identities = 51/163 (31%), Positives = 84/163 (51%), Gaps = 12/163 (7%)
Frame = +1
Query: 334 PMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYS 513
P R+++T L + + + A+ ++ FH ++++ L N++
Sbjct: 25 PSNTGRMSLTTSLTRALKVDLGCDVVEAKDATDKELTSFHGKEFVTELLRQRGSNVEEID 84
Query: 514 KDL-LHYNVGD---------DCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD--IAINWS 657
+ H+N DCP+F GL + G+S+ A KL ++T D +AINW
Sbjct: 85 DEKEAHFNKTSHLEKFGLVYDCPLFCGLDRYVRAVAGSSINSARKLLSDTKDHLLAINWY 144
Query: 658 GGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
GG HH +K +GFCYVNDIV+AI L + + +V Y+D+D+HH
Sbjct: 145 GGRHHCQKNRAAGFCYVNDIVMAINVLRRRYRKVFYLDLDLHH 187
>UniRef50_P39067 Cluster: Acetoin utilization protein acuC; n=25;
Bacillaceae|Rep: Acetoin utilization protein acuC -
Bacillus subtilis
Length = 387
Score = 90.2 bits (214), Expect = 5e-17
Identities = 52/169 (30%), Positives = 81/169 (47%), Gaps = 2/169 (1%)
Frame = +1
Query: 286 YFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDY 465
+ Y+P + + HP R+ +T+ L+ I P AS ++ H++DY
Sbjct: 6 FIYSPSYQTYMFHQEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLVHTDDY 65
Query: 466 IEFLQNVTPQNIQSYSKDLLHYNVG-DDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDI 642
I+ ++ + + + Y +G +D PVF G+ + S+ G +L A + +
Sbjct: 66 IQAVKLAGAGKLPAEEGE--SYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQALH 123
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAILEL-LKYHPRVLYIDIDVHH 786
A N GGLHH + SGFC ND +AI + KY RVLYID D HH
Sbjct: 124 AANLGGGLHHGFRGRASGFCIYNDSAVAIQYIQKKYSARVLYIDTDAHH 172
>UniRef50_O67135 Cluster: Acetoin utilization protein; n=2; Aquifex
aeolicus|Rep: Acetoin utilization protein - Aquifex
aeolicus
Length = 375
Score = 89.0 bits (211), Expect = 1e-16
Identities = 53/165 (32%), Positives = 85/165 (51%), Gaps = 3/165 (1%)
Frame = +1
Query: 301 DVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQ 480
D G + Y HP+K R+++ + L + ++ K A+ ++ FH+EDYI L
Sbjct: 11 DYGKYRYPKNHPLKIPRVSLLLRFLDAMNLIDEKELIKSRPATKEELLLFHTEDYINTLM 70
Query: 481 NVTPQNIQSYSKDLLH-YNVGD-DCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINW 654
+ Q K YN+G + PV +F S+ TG++++ + ++A N
Sbjct: 71 EA--ERCQCVPKGAREKYNIGGYENPVSYAMFTGSSLATGSTVQAIEEFLKG--NVAFNP 126
Query: 655 SGGLHHAKKFEPSGFCYVNDIVIAILELLKY-HPRVLYIDIDVHH 786
+GG+HHA K +GFCY+ND + I L K R+LYID+D HH
Sbjct: 127 AGGMHHAFKSRANGFCYINDPAVGIEYLRKKGFKRILYIDLDAHH 171
>UniRef50_Q2S035 Cluster: Acetoin utilization protein acuC; n=4;
Bacteria|Rep: Acetoin utilization protein acuC -
Salinibacter ruber (strain DSM 13855)
Length = 378
Score = 87.4 bits (207), Expect = 4e-16
Identities = 49/159 (30%), Positives = 78/159 (49%)
Frame = +1
Query: 310 NFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVT 489
++H+GP HP P R +T L+ G + P A+ ++ R H E ++E ++ +
Sbjct: 12 DYHFGPQHPFSPVRQEMTMDLLAALGA--PLNPVAPSVATREEVRRVHGEQFVEKVEAAS 69
Query: 490 PQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLH 669
++ + GD PVFE + G +L GA + + + + GGLH
Sbjct: 70 DGTPPPEAR-AFGLDTGD-VPVFENMDAAARGLVGGTLHGARLIGDGDATRVLQFGGGLH 127
Query: 670 HAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HA + SGFC ND+ +AI L + RV Y+D+DVHH
Sbjct: 128 HAHRARASGFCVYNDLSVAIHALREQGLRVAYVDVDVHH 166
>UniRef50_Q2J786 Cluster: Histone deacetylase superfamily; n=13;
Actinomycetales|Rep: Histone deacetylase superfamily -
Frankia sp. (strain CcI3)
Length = 426
Score = 87.0 bits (206), Expect = 5e-16
Identities = 54/168 (32%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
Frame = +1
Query: 292 YNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKK--MQIYKPYRASAHDMCRFHSEDY 465
++P + + +GP HP+ P RL +T L + G+ ++I +P AS + H Y
Sbjct: 28 WDPVMAGYDFGPTHPLHPVRLELTMDLAMSLGVLDAPGIRISRPTLASDDLIGLIHDPVY 87
Query: 466 IEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIA 645
+ ++ P Q+ L D+ P+FE + + ++ TG ++E A + + A
Sbjct: 88 LSAVR-AAPDPAQARFAALFGLGTADN-PIFERMHEAAALITGGTIEAARAVWSGPPRHA 145
Query: 646 INWSGGLHHAKKFEPSGFCYVNDIVIAILELLKY-HPRVLYIDIDVHH 786
++ +GGLHHA SGFC ND IAI LL RV Y+D+DVHH
Sbjct: 146 VSIAGGLHHAMPGMASGFCIYNDPAIAIAWLLSAGAARVAYVDVDVHH 193
>UniRef50_Q4P6M9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 568
Score = 86.2 bits (204), Expect = 8e-16
Identities = 41/84 (48%), Positives = 51/84 (60%)
Frame = +1
Query: 529 YNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYV 708
+ + DDCP FEGL S+ GA++ A L DIAI W GG HHAKK SGFCY+
Sbjct: 193 FGLQDDCPAFEGLQQHVSLVAGAAITAAELLATGQADIAIAWDGGRHHAKKSSASGFCYI 252
Query: 709 NDIVIAILELLKYHPRVLYIDIDV 780
ND+V+AIL L K PR + + V
Sbjct: 253 NDVVLAILSLRK--PRKVTVTTSV 274
>UniRef50_Q1AX98 Cluster: Histone deacetylase superfamily; n=2;
Bacteria|Rep: Histone deacetylase superfamily -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 387
Score = 85.4 bits (202), Expect = 1e-15
Identities = 52/173 (30%), Positives = 80/173 (46%), Gaps = 3/173 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
R A ++ + + +G HP P R+ +T L GL P S ++ H+
Sbjct: 4 RAAIVHDRSLEEYGFGEDHPFNPLRIRLTLELCDALGLLDGYDFLAPEPVSEEELTSVHT 63
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGD-DCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
Y+ +Q + + LL Y +G D P+F G+ + CS G ++ +
Sbjct: 64 LTYVRMVQQASRG--AGDPERLLDYGLGTPDNPLFAGMHEACSRVVGGTVLACRLVAAGE 121
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP--RVLYIDIDVHH 786
+ A+ SGGLHHA + + SGFC ND +AI L + P RV Y+D D HH
Sbjct: 122 AEHAMCISGGLHHALRSKASGFCIYNDAAVAIALLKRERPGIRVAYVDTDAHH 174
>UniRef50_Q12214 Cluster: Histone deacetylase HOS1; n=2;
Saccharomyces cerevisiae|Rep: Histone deacetylase HOS1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 470
Score = 85.4 bits (202), Expect = 1e-15
Identities = 41/103 (39%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Frame = +1
Query: 481 NVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSG 660
N P + + + YN+ DCP+F L +C + TGA+L L+ I INW G
Sbjct: 148 NDKPTDTYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDG 207
Query: 661 GLHHAKKFEPSGFCYVNDIVIAILELLKYH-PRVLYIDIDVHH 786
G HHA K SGFCY+ND+V+ I L K ++ Y+D D+HH
Sbjct: 208 GRHHAFKQRASGFCYINDVVLLIQRLRKAKLNKITYVDFDLHH 250
>UniRef50_UPI00005A01A4 Cluster: PREDICTED: similar to histone
deacetylase 3 isoform 3; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to histone
deacetylase 3 isoform 3 - Canis familiaris
Length = 75
Score = 85.0 bits (201), Expect = 2e-15
Identities = 35/41 (85%), Positives = 38/41 (92%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKM 402
VAYFY+PDVGNFHYG GHPMKPHRLA+TH LVL YGL+KKM
Sbjct: 5 VAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKM 45
>UniRef50_Q6FWB7 Cluster: Similar to sp|Q12214 Saccharomyces
cerevisiae YPR068c HOS1; n=1; Candida glabrata|Rep:
Similar to sp|Q12214 Saccharomyces cerevisiae YPR068c
HOS1 - Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 445
Score = 84.6 bits (200), Expect = 3e-15
Identities = 41/91 (45%), Positives = 57/91 (62%), Gaps = 2/91 (2%)
Frame = +1
Query: 520 LLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMK-LNNNTCDIAINWSGGLHHAKKFEPSG 696
L +N+ DDCP+F L +C + TGA+L A L + IAINW GG HH+ K + SG
Sbjct: 153 LAKFNLLDDCPIFPYLPLYCYVSTGATLSLAQYILEGSERTIAINWDGGRHHSMKTKASG 212
Query: 697 FCYVNDIVIAILELLKYH-PRVLYIDIDVHH 786
FCY+NDI + I+ L + R+ Y+D D+HH
Sbjct: 213 FCYINDIALLIMTLRRGGVDRISYVDFDLHH 243
>UniRef50_Q6CVU3 Cluster: Similar to sp|Q12214 Saccharomyces
cerevisiae YPR068c HOS1; n=1; Kluyveromyces lactis|Rep:
Similar to sp|Q12214 Saccharomyces cerevisiae YPR068c
HOS1 - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 441
Score = 83.4 bits (197), Expect = 6e-15
Identities = 42/92 (45%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Frame = +1
Query: 514 KDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPS 693
KD Y + DCP F L + + G +L +++ T IAINW GG HHA K S
Sbjct: 142 KDFTKYGLQHDCPKFPFLSMYLQVIVGGTLSLLQHIDHQTPSIAINWDGGRHHALKHYAS 201
Query: 694 GFCYVNDIVIAILEL-LKYHPRVLYIDIDVHH 786
GFCYVNDIV+ I L K RV YID D+H+
Sbjct: 202 GFCYVNDIVLLIQSLRRKGWKRVTYIDFDLHY 233
>UniRef50_A7TRW5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 518
Score = 83.0 bits (196), Expect = 8e-15
Identities = 42/89 (47%), Positives = 58/89 (65%), Gaps = 3/89 (3%)
Frame = +1
Query: 529 YNVGDDCPVFEGLFDFCSMYTGASL--EGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFC 702
+N+ DCP+F L +C + +GASL ++ +++ IAINW GG HHA K + SGFC
Sbjct: 175 FNLEGDCPLFSFLPLYCEVISGASLMLSDFIEKSSSQRTIAINWDGGRHHAIKNKASGFC 234
Query: 703 YVNDIVIAILELLKYH-PRVLYIDIDVHH 786
Y+NDIVI I +L K +V YID D+HH
Sbjct: 235 YINDIVILIQKLRKKGISKVSYIDFDLHH 263
>UniRef50_Q6BS96 Cluster: Similar to CA1453|CaHOS1 Candida albicans
CaHOS1; n=1; Debaryomyces hansenii|Rep: Similar to
CA1453|CaHOS1 Candida albicans CaHOS1 - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 469
Score = 81.0 bits (191), Expect = 3e-14
Identities = 35/95 (36%), Positives = 60/95 (63%), Gaps = 5/95 (5%)
Frame = +1
Query: 517 DLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKL-----NNNTCDIAINWSGGLHHAKK 681
+L Y + DC +F + ++ ++ +S++ A +L +N +I INW GG HH KK
Sbjct: 176 ELETYGLLHDCYIFPFMSEYVNLVAASSIQAATRLTKERKDNRAQNIVINWYGGRHHCKK 235
Query: 682 FEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+ +GFCY+NDIV++I L + + R+ Y+D+D+HH
Sbjct: 236 NKAAGFCYINDIVLSINVLRRNYRRIFYLDLDLHH 270
>UniRef50_Q4R7V0 Cluster: Testis cDNA clone: QtsA-14323, similar to
human histone deacetylase 1 (HDAC1),; n=1; Macaca
fascicularis|Rep: Testis cDNA clone: QtsA-14323, similar
to human histone deacetylase 1 (HDAC1), - Macaca
fascicularis (Crab eating macaque) (Cynomolgus monkey)
Length = 163
Score = 80.2 bits (189), Expect = 5e-14
Identities = 39/129 (30%), Positives = 77/129 (59%)
Frame = -3
Query: 672 MMQAPRPVDGNVTSVII*LHSTFQ*SSSVH*AEIEKTFEYWTVVSNIIVQKIF*VTLYIL 493
M+QA P+ +V ++I HST ++S E+++ +YWTV++ + + V +++
Sbjct: 1 MVQALSPIHSDVRLLLIKFHSTCHRTTSRQLTELKQVVKYWTVLTKVESLHLLAVLRHVI 60
Query: 492 RSYILQKLYVVLAVETAHIVSAGPIRLIYLHFLMKTILQHETMRHSQPVWFHWMPWTVVE 313
+ Q+ VV+A+ H++S G +R I HFL++TI++ + M H+ V HW+ +VV
Sbjct: 61 WTDGAQEFNVVVAMVLGHLLSIGFVRAIDFHFLLETIVEQQIMSHADSVRLHWVALSVVV 120
Query: 312 ITHVRIIEI 286
I+++ I+ +
Sbjct: 121 ISNIPIVVV 129
>UniRef50_Q75BA6 Cluster: ADL339Wp; n=1; Eremothecium gossypii|Rep:
ADL339Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 437
Score = 78.6 bits (185), Expect = 2e-13
Identities = 41/94 (43%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Frame = +1
Query: 511 SKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD-IAINWSGGLHHAKKFE 687
S L Y + DDCPV + L + GA+L A +L+ + +A+NW GG HHA K
Sbjct: 140 SAALAKYGLHDDCPVMDYLPMYIHTVAGATLALAKELSRHRGSALAVNWDGGRHHALKAR 199
Query: 688 PSGFCYVNDIVIAILELLKY-HPRVLYIDIDVHH 786
SGFCYVNDI + I L + RV Y+D D+HH
Sbjct: 200 ASGFCYVNDIALLIQTLRRQGFLRVSYVDFDLHH 233
>UniRef50_Q981B8 Cluster: Acetylpolyamine aminohydrolase; n=4;
Sulfolobaceae|Rep: Acetylpolyamine aminohydrolase -
Sulfolobus solfataricus
Length = 351
Score = 75.8 bits (178), Expect = 1e-12
Identities = 43/170 (25%), Positives = 80/170 (47%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
+ A+ + + N+ + HP K R ++T L+ + G + + +P + HS
Sbjct: 3 KTAFIWTDEYYNYSFPDYHPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLVHS 62
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC 636
++YIEF++ + + Q Y D D P F+G+++ + S++ + +
Sbjct: 63 KEYIEFVKYKSKEG-QGYLDD-------GDTPAFKGIYEAALIRVSGSVKALELIKSGEF 114
Query: 637 DIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+ IN GG HHAK+ +GFC ND+ + + R+ +DID HH
Sbjct: 115 NHTINIGGGFHHAKRNRAAGFCVFNDVALISKLGESFFSRIAIVDIDGHH 164
>UniRef50_P64375 Cluster: Acetoin utilization protein acuC; n=15;
Staphylococcus|Rep: Acetoin utilization protein acuC -
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length = 389
Score = 75.4 bits (177), Expect = 2e-12
Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 2/172 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
+ AY Y+ + + + HP RL +T L+L L QI +P A+ ++ H
Sbjct: 7 KTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGDELMLIHK 66
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGD-DCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
DY+E +++ + I + Y + D + F+ + + G +L A + +
Sbjct: 67 YDYVEAIKHASHGIIS--EDEAKKYGLNDEENGQFKHMHRHSATIVGGALTLADLIMSGK 124
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLK-YHPRVLYIDIDVHH 786
+ GGLHHA+ SGFC NDI I + K Y+ RVL ID D HH
Sbjct: 125 VLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHH 176
>UniRef50_O30107 Cluster: Uncharacterized protein AF_0130; n=2;
Euryarchaeota|Rep: Uncharacterized protein AF_0130 -
Archaeoglobus fulgidus
Length = 359
Score = 72.5 bits (170), Expect = 1e-11
Identities = 47/158 (29%), Positives = 82/158 (51%), Gaps = 4/158 (2%)
Frame = +1
Query: 325 PGHPMKPHRLAVTHCLVLKYGLHKKMQIY--KPYRASAHDMCRFHSEDYIEFLQNVTPQN 498
P HP + RLA T + + G+ + +I +P++AS D+ H+E+Y+ FL+
Sbjct: 18 PTHPERRERLAYTMDQLREEGIFESERIVLLEPFKASLEDVLEVHTEEYVRFLE------ 71
Query: 499 IQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGL-HHA 675
++S ++ ++ + PV G+FD + G ++ A + N C+ A HHA
Sbjct: 72 MESKKGGIIDFDT--NIPV--GVFDRALLAAGGAIRAAQAVLNKECENAFAMIRPPGHHA 127
Query: 676 KKFEPSGFCYVNDIVIAILELLKY-HPRVLYIDIDVHH 786
K + +GFCY+N++ I + LLK R+ +D D HH
Sbjct: 128 KPYIGAGFCYLNNMAIMVKWLLKQGFERIAILDWDAHH 165
>UniRef50_A0L9T2 Cluster: Histone deacetylase superfamily; n=3;
Proteobacteria|Rep: Histone deacetylase superfamily -
Magnetococcus sp. (strain MC-1)
Length = 327
Score = 68.9 bits (161), Expect = 1e-10
Identities = 40/179 (22%), Positives = 74/179 (41%), Gaps = 2/179 (1%)
Frame = +1
Query: 256 LSTMTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAH 435
++ M + + ++ + + GHP R+ + L K+ I P A
Sbjct: 2 VNRMRDATICVYLGEEIAQYGFPDGHPWTTTRMDAFWQEATRQSLSSKVVIADPVMAQPE 61
Query: 436 DMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAM 615
+ FH+ Y+E ++ + + L + D P F G+++ + G+++ A
Sbjct: 62 QLHSFHTPQYVELVKRCSDAG-----EGFLDHG---DTPAFPGIYEAAAYVVGSAVAAAE 113
Query: 616 KLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
++ GLHHA+ GFC ND + + L K H ++ Y+DID HH
Sbjct: 114 QIMQQRFRRIFIPIAGLHHAQPDVAGGFCVFNDAAVVVKHLRKQHGIKKIAYVDIDAHH 172
>UniRef50_Q59Q78 Cluster: Likely histone deacetylase Hos1p; n=2;
Saccharomycetales|Rep: Likely histone deacetylase Hos1p
- Candida albicans (Yeast)
Length = 436
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Frame = +1
Query: 529 YNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD-----IAINWSGGLHHAKKFEPS 693
Y + DC F L + + +S+ A K+ + IA+NW GG HH K +
Sbjct: 150 YGLTFDCYPFPSLDLYVQLTAASSINAARKIVQQVKETKDQIIAVNWYGGRHHCHKSHAA 209
Query: 694 GFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
GFCYVND+V++I L K V Y+D+D+HH
Sbjct: 210 GFCYVNDVVLSINILRKNLGSVFYLDLDLHH 240
>UniRef50_Q381M6 Cluster: Histone deacetylase 2; n=4;
Trypanosoma|Rep: Histone deacetylase 2 - Trypanosoma
brucei
Length = 566
Score = 65.7 bits (153), Expect = 1e-09
Identities = 35/88 (39%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
Frame = +1
Query: 535 VGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVND 714
VGD P F G++ F +L L + AI+W GG H+AK+ G C VND
Sbjct: 146 VGDSAP-FSGMWRFTQAVVSGTLAATRLLAQPSRFAAIHWMGGKHNAKRASAGGSCLVND 204
Query: 715 IVIAILELLKYHPR----VLYIDIDVHH 786
+V+A+LEL K P VL +D+D HH
Sbjct: 205 VVLAVLELRKLLPANRNVVLAVDLDAHH 232
>UniRef50_Q5K8L3 Cluster: Histone deacetylase 3, putative; n=2;
Filobasidiella neoformans|Rep: Histone deacetylase 3,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 555
Score = 64.9 bits (151), Expect = 2e-09
Identities = 38/105 (36%), Positives = 52/105 (49%), Gaps = 19/105 (18%)
Frame = +1
Query: 529 YNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYV 708
YN+ D PVF L + S T A+ L + D A+ W GG HHAK+ E GFCYV
Sbjct: 225 YNLSHDNPVFPTLASYISHVTAATSTACRLLATDKADWAVCWDGGRHHAKRKEAGGFCYV 284
Query: 709 NDIVIAILELLK-------------------YHPRVLYIDIDVHH 786
ND+V+ L L + PR+LY+D+D+H+
Sbjct: 285 NDLVLGGLLLSREGRIPLPLKEGEDPKRQRTRAPRILYLDMDLHY 329
>UniRef50_A5E4H2 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 410
Score = 63.3 bits (147), Expect = 7e-09
Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 12/99 (12%)
Frame = +1
Query: 526 HYNVGDDCPVFEGLFDFCSMYTGASLEGA-----MKLNNNTCD------IAINWSGGLHH 672
+Y + DC VF + + ++ +++E A M +N+ D I INW GG HH
Sbjct: 117 NYGLTHDCYVFPFMRHYVALTAASTIELATHIARMVVNSRDSDDLHIRPIGINWYGGRHH 176
Query: 673 AKKFEPSGFCYVNDIVIAILELLKY-HPRVLYIDIDVHH 786
+ + SGFCY+ND+V+ I L K V Y+D+D+HH
Sbjct: 177 CHRAKCSGFCYINDVVLGINALRKLTSATVFYLDLDLHH 215
>UniRef50_A3JCC1 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=2;
Gammaproteobacteria|Rep: Deacetylases, including yeast
histone deacetylase and acetoin utilization protein -
Marinobacter sp. ELB17
Length = 308
Score = 62.9 bits (146), Expect = 9e-09
Identities = 38/170 (22%), Positives = 75/170 (44%), Gaps = 3/170 (1%)
Frame = +1
Query: 283 AYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSED 462
A+F + D + GP HP +P R+A + L++ + +P + + H E
Sbjct: 4 AFFSHDDCNKHNMGPEHPERPERMAAIQSYLADTALNQDLDYVRPDEITRDQLLIVHPES 63
Query: 463 YIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGA-MKLNNNTCD 639
Y++ L + P + ++ D + + GA+++ M +++ +
Sbjct: 64 YLKQLDMMQPTRGRVFT--------DPDTAMMPDTLRAARLAAGANIQAVDMVMSSQVTN 115
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
+ HHA++ + GFC+ N++ +A + L +H RV ID DVH
Sbjct: 116 AFVCARPPGHHAERSKSMGFCFYNNVALAAMRALSFHRLERVAIIDFDVH 165
>UniRef50_Q64AZ9 Cluster: Deacetylase; n=1; uncultured archaeon
GZfos28B8|Rep: Deacetylase - uncultured archaeon
GZfos28B8
Length = 361
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/177 (23%), Positives = 80/177 (45%), Gaps = 6/177 (3%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
+ ++A Y D+ + +G GHP++ R + H +++ + QI +A+ D+
Sbjct: 2 RSKLAILYRDDLKEYDFGAGHPIRGERYLMFHRFLMENVSEQIYQIIGTEKANDEDLLFI 61
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHY--NVGDDCPVFEG--LFDFCSMYTGASLEGAMK 618
++YI+F + + D Y + D+ PV + + + + G +
Sbjct: 62 CEKEYIDFTRAYYKAANLGFDYDGRFYLFHSADNRPVGKPGKVEEAARLIIGQAKRAVDL 121
Query: 619 LNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
+ + + A++ GGLHHAK GFC ND+ L++ + R+L +D D H
Sbjct: 122 VESGEFEKAVSIGGGLHHAKPSFGEGFCLYNDVAYTAKYLMQEYDLKRILILDTDAH 178
>UniRef50_Q28M71 Cluster: Histone deacetylase superfamily; n=15;
Alphaproteobacteria|Rep: Histone deacetylase superfamily
- Jannaschia sp. (strain CCS1)
Length = 375
Score = 60.9 bits (141), Expect = 4e-08
Identities = 46/159 (28%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Frame = +1
Query: 319 YGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNV-TPQ 495
YG HP++ R++ L G Q RA + +H+ YI LQ Q
Sbjct: 16 YGRWHPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWHTPAYIAALQQAEADQ 75
Query: 496 NIQSYSKDLLHYNVGD-DCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHH 672
+ +D + +G P++ +F + GASL L + + + GG HH
Sbjct: 76 AVTDAVRD--RHGLGTVSNPIYPEMFRRPATAAGASLLAGELLKDG--GVIYHPGGGTHH 131
Query: 673 AKKFEPSGFCYVNDIVIAILELLKYHP-RVLYIDIDVHH 786
+ GFCY+ND V+A+L L + R+ Y+DID HH
Sbjct: 132 GMRDRAGGFCYLNDPVLAMLSLRRNGARRIAYVDIDAHH 170
>UniRef50_A4BCK9 Cluster: Deacetylase, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Reinekea sp. MED297|Rep: Deacetylase, including yeast
histone deacetylase and acetoin utilization protein -
Reinekea sp. MED297
Length = 308
Score = 57.6 bits (133), Expect = 3e-07
Identities = 44/176 (25%), Positives = 76/176 (43%), Gaps = 7/176 (3%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
+ A+ Y+ G HP P R + +++ GL +++ K ++A+ + R H
Sbjct: 3 KTAFIYHEHCELHDMGEDHPESPRRTEIIRERLIESGLMEQLLPLKAFQATKSQILRVHH 62
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGA-----SLEGAMKL 621
Y++ L + P+ + + D G + + + Y A +++G M
Sbjct: 63 STYVDQLDRINPK----------YGLIQADPDTLMGPYTYEASYLAAGAGIQAVDGIMNG 112
Query: 622 NNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
N A+ G HHA+ GFC+ N+I +A LK+H RV ID DVH
Sbjct: 113 AFNRAFCAVRPPG--HHAEPNVTMGFCFFNNIAVAAEHALKHHKLSRVAIIDFDVH 166
>UniRef50_Q8IR37 Cluster: CG6170-PC, isoform C; n=7; Diptera|Rep:
CG6170-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1138
Score = 57.6 bits (133), Expect = 3e-07
Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Frame = +1
Query: 328 GHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQS 507
GHP +P R+ H + YGL K+M+ P A+ ++C H+ ++ ++ + + +
Sbjct: 562 GHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKE 621
Query: 508 YSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGA-MKLNNNTCDIAINWSGGLHHAKKF 684
YN + FD ++ G L+ L + N HHA++
Sbjct: 622 LHDAAGIYN---SVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGICNVRPPGHHAEQD 678
Query: 685 EPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
P GFC N++ IA ++ RVL +D DVHH
Sbjct: 679 HPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHH 714
Score = 47.2 bits (107), Expect = 5e-04
Identities = 36/129 (27%), Positives = 61/129 (47%), Gaps = 5/129 (3%)
Frame = +1
Query: 415 PYRASAHD-MCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYT 591
P R++ D + R H+E++ E L+ + ++L D + F+ + +
Sbjct: 162 PSRSATKDEILRLHTEEHFERLKETSGIRDDERMEELSSRY--DSIYIHPSTFELSLLAS 219
Query: 592 GASLEGAMKLNNNTCD--IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRV 759
G+++E L +AI G HHA K E +G+C+ N++ +A L H R+
Sbjct: 220 GSTIELVDHLVAGKAQNGMAIIRPPG-HHAMKAEYNGYCFFNNVALATQHALDVHKLQRI 278
Query: 760 LYIDIDVHH 786
L ID DVHH
Sbjct: 279 LIIDYDVHH 287
>UniRef50_Q17MD0 Cluster: Histone deacetylase; n=1; Aedes
aegypti|Rep: Histone deacetylase - Aedes aegypti
(Yellowfever mosquito)
Length = 1059
Score = 57.6 bits (133), Expect = 3e-07
Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 7/182 (3%)
Frame = +1
Query: 262 TMTQQRVAYFYNPDV---GNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASA 432
T RV + Y+ + N H HP +P R+A + +Y L +M+ KP A+
Sbjct: 457 TFPANRVCFVYDESLLEHRNVH--EDHPEQPDRVAKIYTRHEEYKLLARMKRLKPRHATT 514
Query: 433 HDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGA 612
++C HS ++ ++ + D +N F+ ++ G+ L+
Sbjct: 515 TELCMVHSRQHVNVIRRTVEREEMKQVAD--QFN---SVYFHPKTFECATLAAGSVLQVV 569
Query: 613 MKLNN--NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDV 780
++ N + + I G HHA+ P GFC N++ IA ++ H RVL +D DV
Sbjct: 570 DEVLNGQSRSGVCIVRPPG-HHAESDMPHGFCIFNNVAIAAQYAIRDHGLKRVLIVDWDV 628
Query: 781 HH 786
HH
Sbjct: 629 HH 630
Score = 44.4 bits (100), Expect = 0.003
Identities = 38/158 (24%), Positives = 72/158 (45%), Gaps = 5/158 (3%)
Frame = +1
Query: 328 GHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVT-PQNIQ 504
G+P P R + GL + ++ +P A+ ++ H+ + +E L+ ++++
Sbjct: 51 GYPECPERFTRVLERCRELGLVDRCKMIEPRMATEEEILTKHTPEQVEILRGTKGSEDLE 110
Query: 505 SYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLE--GAMKLNNNTCDIAINWSGGLHHAK 678
+ HY D V +D + G+++E A+ +AI G HHA
Sbjct: 111 RLEELSSHY---DAVFVHPSSYDCSLLACGSTIELVDAVVGGRVQNGMAIIRPPG-HHAM 166
Query: 679 KFEPSGFCYVNDIVIAILELLKY--HPRVLYIDIDVHH 786
K E +G+C+ N++ IA L ++L +D D+HH
Sbjct: 167 KAEYNGYCFFNNVAIAAQHALDRLGLKKILVVDWDIHH 204
>UniRef50_A1RXP5 Cluster: Histone deacetylase superfamily; n=1;
Thermofilum pendens Hrk 5|Rep: Histone deacetylase
superfamily - Thermofilum pendens (strain Hrk 5)
Length = 360
Score = 57.6 bits (133), Expect = 3e-07
Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 1/131 (0%)
Frame = +1
Query: 397 KMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDF 576
K+++++ R + H ++Y+++++ ++ LL Y D P + G+F+
Sbjct: 51 KVEVHEVKRYPESVLLLAHDKEYVDYVKRMS-----ELGAGLLDYG---DTPAYPGVFEK 102
Query: 577 CSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELL-KYHP 753
+ +L A L +A N GG HHA++ GFC ND+ +A + + +
Sbjct: 103 ALLAVSGTLTLADILVKAGRGVAFNPQGGFHHARRRSAGGFCVFNDVAVAARYVRERGYE 162
Query: 754 RVLYIDIDVHH 786
RV ID+D HH
Sbjct: 163 RVAIIDVDAHH 173
>UniRef50_UPI0000DB73BE Cluster: PREDICTED: similar to HDAC6
CG6170-PA, isoform A; n=2; Apis mellifera|Rep:
PREDICTED: similar to HDAC6 CG6170-PA, isoform A - Apis
mellifera
Length = 1019
Score = 57.2 bits (132), Expect = 4e-07
Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 4/156 (2%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
HP KPHR+ + + +Y L + + + A+ ++ H+++YI+ ++N +
Sbjct: 485 HPEKPHRINIIYKKFQEYNLLDRSFVQQGRSATKEELLLVHTKEYIDKIKNTKNLKSKEL 544
Query: 511 SKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNN--NTCDIAINWSGGLHHAKKF 684
K YN + + + TG+ L+ + N + IAI G HHA +
Sbjct: 545 KKQAETYN---SVYLHPETWSSACISTGSLLQVVDNVLNGESQSGIAIIRPPG-HHATED 600
Query: 685 EPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
GFC N++ IA +++H RVL +D DVH+
Sbjct: 601 AACGFCIFNNVAIAAKYAIEFHHVKRVLIVDWDVHY 636
Score = 39.9 bits (89), Expect = 0.071
Identities = 38/156 (24%), Positives = 70/156 (44%), Gaps = 4/156 (2%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
+P P RL + GL + ++ P AS +++ HS++ I+ L++ T
Sbjct: 105 YPECPARLIRVLQRCEELGLISRCKLITPRLASENEILIKHSQEQIDILKS-TDGCTDIN 163
Query: 511 SKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD--IAINWSGGLHHAKKF 684
+ +LL D + + + G+++ + +AI G HHA K
Sbjct: 164 NLELLSSKY-DAIYIHPSTYRLSLLAVGSTINLVESICKGEIQNGMAIIRPPG-HHAMKS 221
Query: 685 EPSGFCYVNDIVIAILELL--KYHPRVLYIDIDVHH 786
E G+C+ N++ IA ++L ++L +D DVHH
Sbjct: 222 EYCGYCFFNNVAIAAEKVLCNNLASKILIVDWDVHH 257
>UniRef50_Q8F254 Cluster: Histone deacetylase family protein; n=4;
Leptospira|Rep: Histone deacetylase family protein -
Leptospira interrogans
Length = 302
Score = 57.2 bits (132), Expect = 4e-07
Identities = 48/174 (27%), Positives = 78/174 (44%), Gaps = 4/174 (2%)
Frame = +1
Query: 274 QRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFH 453
+R+ Y+PD N GP H + + + LV + + IYKP A D+ H
Sbjct: 6 ERIGLVYHPDY-NLDLGP-HVFPARKYQMVYDLVKRDSKLSNLYIYKPDLAKTKDLSLVH 63
Query: 454 SEDYIE--FLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNN 627
++++++ F N+T + YS+ L + + G T S+E A K
Sbjct: 64 TQEFLDDFFSLNITERT--QYSELPLTKQIVHSFVLAVG-------GTILSMELAQKYK- 113
Query: 628 NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP--RVLYIDIDVH 783
+ GG HH+ GFCY+ND IA K +P ++L+ID+D+H
Sbjct: 114 ----FVYHIGGGFHHSMPDRAEGFCYLNDAAIASKLYQKEYPDKKILFIDLDLH 163
>UniRef50_Q7NRU4 Cluster: Histone deacetylase; n=54;
Proteobacteria|Rep: Histone deacetylase -
Chromobacterium violaceum
Length = 319
Score = 57.2 bits (132), Expect = 4e-07
Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 7/175 (4%)
Frame = +1
Query: 283 AYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSED 462
AY +PD + G GHP P RL ++ + +Q + S + R H
Sbjct: 16 AYVTHPDCLQHNMGVGHPECPERLTAIRDQLMASQIFDSLQEIEAPEVSYEQLARVHPPR 75
Query: 463 YIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAM-----KLNN 627
Y+E+L+ P ++ ++ D D + G GA ++ K N
Sbjct: 76 YVEYLEACAP-SVGTFRMD-------PDTAMSPGTLKAARRAAGAVVKAVELVAEDKAPN 127
Query: 628 NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
C AI G HHA+ + GFC+ N++ + + L ++ RV +D DVHH
Sbjct: 128 AFC--AIRPPG--HHAESDKAMGFCFFNNLAVGVTHALAHYKFERVAVVDFDVHH 178
>UniRef50_Q7VZF1 Cluster: Histone deacetylase family protein; n=6;
Proteobacteria|Rep: Histone deacetylase family protein -
Bordetella pertussis
Length = 307
Score = 56.0 bits (129), Expect = 1e-06
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 3/170 (1%)
Frame = +1
Query: 286 YFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDY 465
Y +P G HP P RL +L GL +Q + AS D+ R H+ Y
Sbjct: 5 YLTHPSCRLHEMGDWHPESPQRLDAISDQLLASGLLPYLQERQAPEASRADILRVHTPAY 64
Query: 466 IEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGA-MKLNNNTCDI 642
++ L+ P++ +Y + D + ++ GA + L
Sbjct: 65 LDSLRAHQPEHG--------YYAIDADTSMNRHTYEAALRAAGAGVAAVDAVLGGEAITA 116
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+ HHA++ GFC++N++ IA L +H RV +D DVHH
Sbjct: 117 FCSVRPPGHHAERDHAMGFCFLNNVAIAARHALDFHGLQRVALVDFDVHH 166
>UniRef50_Q803K0 Cluster: Zgc:55652; n=4; Danio rerio|Rep: Zgc:55652
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 676
Score = 55.6 bits (128), Expect = 1e-06
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 5/153 (3%)
Frame = +1
Query: 343 PHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDL 522
P RL V++ + +GL ++ + +A+ ++ HSE+Y+E ++ N++
Sbjct: 30 PERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFS 89
Query: 523 LHYNVGDDCPVFEGLFDFCSMYTGASL---EGAMKLNNNTCDIAINWSGGLHHAKKFEPS 693
YN D + ++ + GA+L + MK + G HH+++ +
Sbjct: 90 KKYN---DVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPG--HHSQRSAAN 144
Query: 694 GFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
GFC N++ A L K + R+L +D DVHH
Sbjct: 145 GFCVFNNVAFAALYAKKNYNLNRILIVDWDVHH 177
>UniRef50_Q5QWS4 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Idiomarina|Rep: Histone
deacetylase/AcuC/AphA family protein - Idiomarina
loihiensis
Length = 311
Score = 55.2 bits (127), Expect = 2e-06
Identities = 26/53 (49%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = +1
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP--RVLYIDIDVH 783
T +AI++SGG HHA K SGFC +ND+ IA E+L HP +++ +D DVH
Sbjct: 111 TKGVAIHFSGGYHHAHKDWGSGFCLLNDLAIACNEILVRHPKLKIVVLDTDVH 163
>UniRef50_Q97Z24 Cluster: Acetoin utilization protein; n=3;
Sulfolobaceae|Rep: Acetoin utilization protein -
Sulfolobus solfataricus
Length = 348
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/125 (29%), Positives = 58/125 (46%)
Frame = +1
Query: 412 KPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYT 591
+P A+ D+ H+ DYI L+ +S + + D + G+F+ +
Sbjct: 55 RPEYATKEDLMVVHTRDYIGLLE-------ESSKIPYIGFLDQGDTVHYPGMFEDILLVL 107
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYID 771
G+S A+K + D GG HHA GFC +ND+ I L+LL+ RV +D
Sbjct: 108 GSSFT-AIKYSK-FLDYVYIPLGGFHHAMPNRAVGFCPINDVAITALKLLEKGERVAIVD 165
Query: 772 IDVHH 786
+D HH
Sbjct: 166 VDAHH 170
>UniRef50_Q2S0V9 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Bacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Salinibacter
ruber (strain DSM 13855)
Length = 307
Score = 54.8 bits (126), Expect = 2e-06
Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 2/154 (1%)
Frame = +1
Query: 328 GHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQS 507
GHP + H +L L + + P +A D+ R H+ DY+ L +
Sbjct: 16 GHPFPMAKFPALHQRLLDEDLIRPTDVVAPRQADWTDLRRVHTADYLTHLA-------EG 68
Query: 508 YSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFE 687
D +G P E L + ++ A+ T +A N +GG HHA
Sbjct: 69 SLSDHAERRMG--LPWSERLVYRSRLAVQGTINAALMAL--TDGVAANLAGGTHHAFPGH 124
Query: 688 PSGFCYVNDIVIAI--LELLKYHPRVLYIDIDVH 783
GFC +ND+ +AI L+ + RVL +D+DVH
Sbjct: 125 GEGFCVLNDVAVAIRVLQAACWAQRVLIVDLDVH 158
>UniRef50_A6ND61 Cluster: Uncharacterized protein HDAC8; n=3;
Simiiformes|Rep: Uncharacterized protein HDAC8 - Homo
sapiens (Human)
Length = 139
Score = 53.6 bits (123), Expect = 5e-06
Identities = 21/41 (51%), Positives = 29/41 (70%)
Frame = +1
Query: 664 LHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
LH + E SGFCY+ND V+ IL L + R+LY+D+D+HH
Sbjct: 50 LHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH 90
>UniRef50_A7HFZ2 Cluster: Histone deacetylase superfamily; n=4;
Cystobacterineae|Rep: Histone deacetylase superfamily -
Anaeromyxobacter sp. Fw109-5
Length = 589
Score = 52.8 bits (121), Expect = 9e-06
Identities = 43/152 (28%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +1
Query: 337 MKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQS-YS 513
M+P R + + G I+ P R + D+ R H+ + +E L P+N+ ++
Sbjct: 41 MEPRRADFALWWLRECGAVPTRAIHSPRRIAYDDLARVHTPELLESLGR--PENVAHIFA 98
Query: 514 KDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPS 693
D D PV E + + GA+L A + T A+N GG HHA
Sbjct: 99 VD------PSDVPVDE-VMTTIRLACGATLS-ATRETLRTKQPALNLLGGFHHASPGAAG 150
Query: 694 GFCYVNDIVIAILELLK--YHPRVLYIDIDVH 783
GFC VND+ +A+ + + RV+ +D+D H
Sbjct: 151 GFCPVNDVAVALAAVRAEGFTDRVVVLDLDAH 182
>UniRef50_A3CT27 Cluster: Histone deacetylase superfamily; n=2;
Methanoculleus marisnigri JR1|Rep: Histone deacetylase
superfamily - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 330
Score = 52.0 bits (119), Expect = 2e-05
Identities = 43/162 (26%), Positives = 68/162 (41%)
Frame = +1
Query: 301 DVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQ 480
D+ + H PGHP RL G+ + P RA+ D+ H+E +IE ++
Sbjct: 9 DLFSAHDAPGHPESQARLDAALA-----GVPADARRIAPERATVDDLALVHTERHIEGVR 63
Query: 481 NVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSG 660
+ + ++ L D V G FD TGA+ + + + A+
Sbjct: 64 SFCRECPPGRARYL-----DPDTYVTAGSFDAALYATGAAWQAVERALDGEHSFALVRPP 118
Query: 661 GLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
G HHA GFC N++ +A + L RV +D D+HH
Sbjct: 119 G-HHAAPDRAMGFCLFNNVAVATAKALLSIGRVAVVDWDLHH 159
>UniRef50_Q00UC4 Cluster: Histone deacetylase superfamily; n=2;
Ostreococcus|Rep: Histone deacetylase superfamily -
Ostreococcus tauri
Length = 351
Score = 51.2 bits (117), Expect = 3e-05
Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Frame = +1
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
C +A+N +GG HHAK GFC +ND+ A L +L RV+ +D+DVH
Sbjct: 154 CGLAVNTAGGTHHAKGTRGGGFCILNDLATASLAVLNSGRLSRVMIVDLDVH 205
>UniRef50_Q57ET7 Cluster: Histone deacetylase family protein; n=33;
Bacteria|Rep: Histone deacetylase family protein -
Brucella abortus
Length = 337
Score = 50.8 bits (116), Expect = 4e-05
Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 3/157 (1%)
Frame = +1
Query: 325 PGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQ 504
PGHP +P R+ + ++ ++ P+ A + H E+++E +++ P+ ++
Sbjct: 39 PGHPERPDRIRALMSELEGPDFYRLDRVEAPHAGEAAILLA-HPEEHLEAVRSKIPEPVE 97
Query: 505 SYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD-IAINWSGGLHHAKK 681
+ D V D GA++ + + D + + HHA++
Sbjct: 98 DGEASQPIVKLDGDTYVSPKSMDAALTAIGAAMAAVDDVMSGAADNVFVASRPPGHHAER 157
Query: 682 FEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
GFC N+I IA ++H R+ +D DVHH
Sbjct: 158 SRAMGFCVFNNIAIAARHAQRHHGLERIAIVDGDVHH 194
>UniRef50_Q31HC2 Cluster: Histone deacetylase family protein; n=1;
Thiomicrospira crunogena XCL-2|Rep: Histone deacetylase
family protein - Thiomicrospira crunogena (strain XCL-2)
Length = 306
Score = 50.8 bits (116), Expect = 4e-05
Identities = 50/175 (28%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Frame = +1
Query: 286 YFYNPDVGNFHYGPGHPMKPHRL-----AVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
Y +P G GHP R+ A+T +L LHK + A+ D+ R
Sbjct: 4 YLSSPLCQQHSNGWGHPENAQRVVRIEQALTDARLLSNTLHKSI-----LPATEIDVLRV 58
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
HS + E L+ P+N + K + +D + G + +GA L + +
Sbjct: 59 HSSPFWETLKKHLPEN--GFVK------IDEDTSLSPGSLESALAASGAMLTAIDAIMHR 110
Query: 631 TCDIAI-NWSGGLHHAKKFEPSGFCYVNDIVI-AILELLKYH-PRVLYIDIDVHH 786
A N HHA++ P GFC +N I I A L KY R++ +D DVHH
Sbjct: 111 EAKQAFCNIRPPGHHAERNRPMGFCLINHIAIGAAYALEKYALERIVIVDFDVHH 165
>UniRef50_O67877 Cluster: Acetoin utilization protein; n=3;
Bacteria|Rep: Acetoin utilization protein - Aquifex
aeolicus
Length = 310
Score = 50.4 bits (115), Expect = 5e-05
Identities = 49/176 (27%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Frame = +1
Query: 274 QRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFH 453
++V + Y+ D+ H P HP +RL V K G+ K + KP RA ++ H
Sbjct: 2 KKVGFIYD-DIYLKHDWPEHPENKNRLISILEHVEKSGIKKALIDVKPRRAKVEEVALNH 60
Query: 454 SEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
YI Q I + K Y + D +D G LEG ++ +
Sbjct: 61 DPAYI--------QEIHDFCKSGGGY-LDPDTYATPDTYDVALYAVGGVLEGIDRILSGE 111
Query: 634 CD---IAINWSGGLHHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
D A+ G HHA+ + GFC N++ I L +K +V ID D HH
Sbjct: 112 LDRAFCAVRPPG--HHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIIDFDAHH 165
>UniRef50_UPI00015BAE44 Cluster: histone deacetylase superfamily;
n=1; Ignicoccus hospitalis KIN4/I|Rep: histone
deacetylase superfamily - Ignicoccus hospitalis KIN4/I
Length = 326
Score = 50.0 bits (114), Expect = 7e-05
Identities = 21/43 (48%), Positives = 26/43 (60%)
Frame = +1
Query: 658 GGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
GGLHHA K +GFC ND+ + L + RV Y+D DVHH
Sbjct: 113 GGLHHAGKCRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHH 155
>UniRef50_UPI0000F2E91A Cluster: PREDICTED: similar to histone
deacetylase 6,; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to histone deacetylase 6, -
Monodelphis domestica
Length = 1143
Score = 50.0 bits (114), Expect = 7e-05
Identities = 42/167 (25%), Positives = 77/167 (46%), Gaps = 6/167 (3%)
Frame = +1
Query: 304 VGNFH--YGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFL 477
+ +FH + P +P RL + + L ++ + + A+ ++ HS++Y++ +
Sbjct: 163 MSSFHCPWDESFPERPERLQAVQEQLARDCLLERCLLIEAQPATPEELQLVHSQEYVDLM 222
Query: 478 QNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLE--GAMKLNNNTCDIAIN 651
+ TPQ +S + L + D + F + TGA L A+ +A+
Sbjct: 223 AS-TPQMTESERRALS--DTYDSVYLHPNSFPCALLATGALLRLVDALMTGEIRNGLAVV 279
Query: 652 WSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
G HHA++ +G+C N+I IA + H R+L +D DVHH
Sbjct: 280 RPPG-HHAQRESMNGYCMFNNIAIAARYAQERHHVARILIVDWDVHH 325
Score = 47.6 bits (108), Expect = 4e-04
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 7/159 (4%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
HP +P R+A ++ GL + + A+ ++ HSE+YIE ++ + +
Sbjct: 575 HPERPERIAQIAQHHMELGLTPRCFVLPARSATNQELLACHSEEYIERIRATSGLKPRDL 634
Query: 511 SKDLLHYNVGDDCPVFEGLFDFC--SMYTGAS--LEGAMKLNNNTCDIAINWSGGLHHAK 678
++ YN ++ FC + GA+ L A+ +AI G HHA+
Sbjct: 635 HREGTSYN-----SIYISPHSFCCAQLAAGAACRLVEAILAREVQNGLAIVRPPG-HHAE 688
Query: 679 KFEPSGFCYVNDIVIA---ILELLKYHPRVLYIDIDVHH 786
+ GFC+ N + +A E+ R+L +D D+HH
Sbjct: 689 RDAACGFCFFNSVAVAARHAQEVAGRALRILIVDWDIHH 727
>UniRef50_Q0LS19 Cluster: Histone deacetylase superfamily; n=1;
Caulobacter sp. K31|Rep: Histone deacetylase superfamily
- Caulobacter sp. K31
Length = 379
Score = 49.6 bits (113), Expect = 9e-05
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Frame = +1
Query: 538 GDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD--IAINWSGGLHHAKKFEPSGFCYVN 711
GDD PV G F+ S+ G ++ + + D A+ G HH++ GFC +
Sbjct: 97 GDDAPVPYGAFEIASLAAGGAIAAVDAVMSGEVDNAYALLRPAG-HHSRPDRSMGFCIFS 155
Query: 712 DIVIAILELLKYH--PRVLYIDIDVHH 786
+ IA LL +H R+ Y+D DVHH
Sbjct: 156 NAAIAGRHLLDFHNVKRIAYVDWDVHH 182
>UniRef50_Q9UBN7 Cluster: Histone deacetylase 6; n=38; Eutheria|Rep:
Histone deacetylase 6 - Homo sapiens (Human)
Length = 1215
Score = 49.2 bits (112), Expect = 1e-04
Identities = 43/179 (24%), Positives = 76/179 (42%), Gaps = 7/179 (3%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFH--YGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMC 444
Q R Y+ ++ N + HP P R+ C + + GL + P A+ ++
Sbjct: 478 QSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELL 537
Query: 445 RFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGAS--LEGAMK 618
HS +Y+ L+ + ++ +++ CP F + TGA+ L A+
Sbjct: 538 TCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICP---STFACAQLATGAACRLVEAVL 594
Query: 619 LNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAI--LELLKYHP-RVLYIDIDVHH 786
A+ G HHA++ GFC+ N + +A + + H R+L +D DVHH
Sbjct: 595 SGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHH 652
Score = 35.5 bits (78), Expect = 1.5
Identities = 40/173 (23%), Positives = 64/173 (36%), Gaps = 12/173 (6%)
Frame = +1
Query: 304 VGNFH--YGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFL 477
+ FH + P P RL +++ GL + ++ A ++ HS +YI+ +
Sbjct: 94 LNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLM 153
Query: 478 QNVTPQN-------IQSYSKDLLHYN-VGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
+ N +Y LH N C + GA + M +
Sbjct: 154 ETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAI---- 209
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
I G HHA+ G+C N + +A + H RVL +D DVHH
Sbjct: 210 ----IRPPG--HHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHH 256
>UniRef50_A7HL59 Cluster: Histone deacetylase superfamily; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Histone
deacetylase superfamily - Fervidobacterium nodosum
Rt17-B1
Length = 325
Score = 48.8 bits (111), Expect = 2e-04
Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 5/157 (3%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
+P +P RL LV ++ L K +P S + H EDYIE+++ + + Q Y
Sbjct: 32 NPERPSRLK----LVYEF-LKKNYPEVQPLGFSESVLYLAHEEDYIEYIKRKSSEVTQEY 86
Query: 511 SKDLLHYNVGDDC--PVFEGLFD--FCSMYTGAS-LEGAMKLNNNTCDIAINWSGGLHHA 675
++ + D P+ + + F ++ T S LE L+N A+ G HHA
Sbjct: 87 IPEVFFVDKIFDTGTPINKETYKAAFGAVETVLSALE--YSLSNKVIVYALTRPPG-HHA 143
Query: 676 KKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
K G+CY N++ IA L + RV +D+D HH
Sbjct: 144 MKKYGGGYCYFNNVAIAAKYLEEKGMRVAILDLDFHH 180
>UniRef50_Q9K0J2 Cluster: Histone deacetylase family protein; n=4;
Neisseria|Rep: Histone deacetylase family protein -
Neisseria meningitidis serogroup B
Length = 369
Score = 48.4 bits (110), Expect = 2e-04
Identities = 36/173 (20%), Positives = 67/173 (38%), Gaps = 3/173 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
R A+ +P G HP P R+ + + G+ + +Q + S + HS
Sbjct: 23 RTAWISHPACAGHEPGANHPDSPDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALVHS 82
Query: 457 EDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGA-MKLNNNT 633
Y+ L++ PQ + D +D + G G++++ M +N
Sbjct: 83 SKYLNRLESCLPQKGKISRLD-------NDTAISTGSLSAARFAAGSAVQAVDMVMNRKA 135
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA + GFC +N++ ++ + + R+ ID DVH+
Sbjct: 136 WHAFCAARPPGHHAGSGKAGGFCLLNNVAAGVMHAIAEYRLKRIAVIDFDVHY 188
>UniRef50_Q8D858 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=31; Gammaproteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Vibrio vulnificus
Length = 312
Score = 48.4 bits (110), Expect = 2e-04
Identities = 25/51 (49%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+AI+ SGG HHA SGFC ND+V+A + L++ +VL ID DVHH
Sbjct: 118 VAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKVLIIDSDVHH 168
>UniRef50_UPI00015BB127 Cluster: histone deacetylase superfamily;
n=1; Ignicoccus hospitalis KIN4/I|Rep: histone
deacetylase superfamily - Ignicoccus hospitalis KIN4/I
Length = 345
Score = 48.0 bits (109), Expect = 3e-04
Identities = 36/153 (23%), Positives = 65/153 (42%)
Frame = +1
Query: 325 PGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQ 504
PGHP P R+ L+ + L +++ P ++ H DY+E+++ V
Sbjct: 18 PGHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVHDRDYVEYVKRVIEAGGG 77
Query: 505 SYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKF 684
D + P + + + + A++ ++ A+ G HHA++
Sbjct: 78 YLDPDTYASPTSWE-PAL-----YAAGTVAYAAQRAVEGDHWLAFAAVRPPG--HHARRS 129
Query: 685 EPSGFCYVNDIVIAILELLKYHPRVLYIDIDVH 783
E GFC N++ +A L + RV +DIDVH
Sbjct: 130 EGRGFCIFNNVALAAEVLRRRGMRVAVVDIDVH 162
>UniRef50_A6T202 Cluster: Histone deacetylase superfamily protein;
n=1; Janthinobacterium sp. Marseille|Rep: Histone
deacetylase superfamily protein - Janthinobacterium sp.
(strain Marseille) (Minibacterium massiliensis)
Length = 322
Score = 47.6 bits (108), Expect = 4e-04
Identities = 42/187 (22%), Positives = 77/187 (41%), Gaps = 3/187 (1%)
Frame = +1
Query: 235 VERIRICLSTMTQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYK 414
+E++ +C +++ V Y ++ + + GP HP P RL L+ ++
Sbjct: 1 MEKMPLCQASINMTTVIYTHDACLEH-KPGPSHPESPERLKAV-LRALRVPEFDAVEWRD 58
Query: 415 PYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTG 594
+ + H+ED++ +++ +P + + + G D + G + G
Sbjct: 59 APMGTREQVLLIHTEDFVTDVEDASPH------RGYMPLD-GGDTVMSPGSLEAVMRCVG 111
Query: 595 ASLEGA-MKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLY 765
A+ G + L+N ++ HHA+ GFC N IA + H RV
Sbjct: 112 AACAGVDLVLDNEAHNVFCATRPCGHHAEPSRAMGFCIYNQAAIAAAYAYEVHKLERVAV 171
Query: 766 IDIDVHH 786
ID DVHH
Sbjct: 172 IDFDVHH 178
>UniRef50_Q0YKV4 Cluster: Histone deacetylase superfamily; n=1;
Geobacter sp. FRC-32|Rep: Histone deacetylase
superfamily - Geobacter sp. FRC-32
Length = 370
Score = 47.2 bits (107), Expect = 5e-04
Identities = 49/174 (28%), Positives = 66/174 (37%), Gaps = 4/174 (2%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRL-AVTH-CLVLKYGLHKKMQIYKPYRASAHDMCRF 450
R F +PD HP P RL ++ H C L L Q+ P A+ +
Sbjct: 51 RFVLFSHPDCLLHRVREDHPETPARLESILHGCAALPASLPLSFQVPPP--ATVAQLQLV 108
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
H E Y+ L+ Q + H CP F G +L L N
Sbjct: 109 HEEKYLLNLEAACRQRDPLFMTPDNHI-----CP---DTFRAVLAAAGCALALGETLLEN 160
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP--RVLYIDIDVHH 786
A+ G HHA + GFC+VN I +AI + + P L +D DVHH
Sbjct: 161 GAGFALVRPPG-HHAGRKSAEGFCFVNHIALAIETIRQRQPAANFLVVDFDVHH 213
>UniRef50_A6FY71 Cluster: Histone deacetylase superfamily protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Histone
deacetylase superfamily protein - Plesiocystis pacifica
SIR-1
Length = 623
Score = 47.2 bits (107), Expect = 5e-04
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVH 783
+A+N GG HHA++ GFC +ND+ +AI EL + + +D+D+H
Sbjct: 139 LAVNLGGGFHHARRDRAGGFCLLNDVAVAIAELRASGFTGPISVVDLDLH 188
>UniRef50_Q31EP6 Cluster: Histone deacetylase family protein
precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
Histone deacetylase family protein precursor -
Thiomicrospira crunogena (strain XCL-2)
Length = 379
Score = 46.8 bits (106), Expect = 6e-04
Identities = 42/161 (26%), Positives = 68/161 (42%), Gaps = 4/161 (2%)
Frame = +1
Query: 316 HYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQ 495
H GHP RL + + K G+ ++ A+ ++ H++ YI+ ++
Sbjct: 49 HDMSGHPENAQRLVAINNEMEKQGIWPQLTPVATRLATNEELLLAHTQSYIDEIE----- 103
Query: 496 NIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD--IAINWSGGLH 669
I S S + D + FD M G+++ + + + D A+ G H
Sbjct: 104 -ILSDSGGGFYEPYQGDTYLNASSFDAAKMAAGSNINLNLAIYDRKIDHGFALLRPPG-H 161
Query: 670 HAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HA + + GFC N +IA L KY R+ ID DVHH
Sbjct: 162 HALQNKAMGFCIFNSDIIAARALQKYRGVKRIAIIDFDVHH 202
>UniRef50_Q2IF50 Cluster: Histone deacetylase superfamily; n=1;
Anaeromyxobacter dehalogenans 2CP-C|Rep: Histone
deacetylase superfamily - Anaeromyxobacter dehalogenans
(strain 2CP-C)
Length = 324
Score = 46.8 bits (106), Expect = 6e-04
Identities = 45/176 (25%), Positives = 73/176 (41%), Gaps = 5/176 (2%)
Frame = +1
Query: 274 QRVAYFYNPDVGNFHYGPGHPMKPHRL-AVTHCLVLKYGLHKK-MQIYKPYRASAHDMCR 447
QRV +PD GPGHP + RL A L L + ++ + RA+ + R
Sbjct: 3 QRVLLVSHPDCQAHDPGPGHPERQARLEAALEALAADPALGPEVLERVEAARATEQALLR 62
Query: 448 FHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNN 627
H+ ++ ++ ++ D L + PV G + GA++E A ++
Sbjct: 63 VHTPGHLARVRGHVEAAARTGMLDWLE----PETPVSAGSWRAAVAAAGAAIEAAERVAR 118
Query: 628 NTCDIAINW-SGGLHHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
A HHA G+C +N++ IA ++ RVL +D DVHH
Sbjct: 119 GEARAAFALVRPPGHHAWADRAGGYCLLNNVAIAARAVQAAGLARRVLVVDWDVHH 174
>UniRef50_Q12GF8 Cluster: Histone deacetylase superfamily; n=6;
Burkholderiales|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 353
Score = 46.8 bits (106), Expect = 6e-04
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA + SGFCYVN+ A LL+++ RV +D+D HH
Sbjct: 168 HHACRDSASGFCYVNNSACAAHRLLQHYGRVAVLDVDAHH 207
>UniRef50_A4C9H1 Cluster: Putative histone deacetylase family
protein; n=2; Pseudoalteromonas|Rep: Putative histone
deacetylase family protein - Pseudoalteromonas tunicata
D2
Length = 302
Score = 46.8 bits (106), Expect = 6e-04
Identities = 48/167 (28%), Positives = 72/167 (43%), Gaps = 3/167 (1%)
Frame = +1
Query: 292 YNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIE 471
Y+P+ +F + P H + A + +++ G + I+KP RAS ++ + H Y+
Sbjct: 11 YHPNY-SFEFDPNHRFVMSKFADLYQHLVQTG-YVNHNIFKPLRASISELEKVHCSRYLH 68
Query: 472 FLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYT-GASLEGAMKLNNNTCDIAI 648
L T Q S+ +G P E L + G L + L N IA
Sbjct: 69 QLNQNTLD--QKASR-----RIG--LPWSEQLMARTFIEAQGTLLTAQLALKNG---IAC 116
Query: 649 NWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
+ +GG HHA SGFC VND+ L+ VL D+DVH
Sbjct: 117 HLAGGTHHAHYDFGSGFCMVNDLAYTAASLIDSGDVTNVLIFDLDVH 163
>UniRef50_A0Y3M1 Cluster: Histone deacetylase family protein; n=1;
Alteromonadales bacterium TW-7|Rep: Histone deacetylase
family protein - Alteromonadales bacterium TW-7
Length = 299
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/126 (30%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Frame = +1
Query: 412 KPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYT 591
+P +A + HSE YI N N+ + + + P L + +
Sbjct: 44 QPAKARPSQLALCHSEHYIN---NFLTGNLSDKAIKKMGF------PYSAQLVERTLLSV 94
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLY 765
G S++ A + + + N SGG HHA SGFC ND+ IA LL H VL
Sbjct: 95 GGSIQAAEEALKS--GLTCNLSGGYHHAYSDYGSGFCIFNDLAIAATHLLSTHKAKTVLI 152
Query: 766 IDIDVH 783
D DVH
Sbjct: 153 FDCDVH 158
>UniRef50_Q4FNF7 Cluster: Histone deacetylase family protein; n=5;
Bacteria|Rep: Histone deacetylase family protein -
Pelagibacter ubique
Length = 309
Score = 46.4 bits (105), Expect = 8e-04
Identities = 40/161 (24%), Positives = 69/161 (42%), Gaps = 2/161 (1%)
Frame = +1
Query: 310 NFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVT 489
N + G GHP K R+ V K +K + KP + + + H+ DYI F++
Sbjct: 13 NHNTGDGHPEKIDRVTVVIDNFKKLD-NKNLIWKKPSKFNRSLLEITHNSDYINFVEKSF 71
Query: 490 PQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLH 669
P+ S+ + G + + + +++G + A+ G H
Sbjct: 72 PEKGLSFLDGDTIVSPGSKDATLDAVGSIIT-----AIDGVQNKDFKNAFCAVRPPG--H 124
Query: 670 HAKKFEPSGFCYVNDIVIAILELL-KYH-PRVLYIDIDVHH 786
HA+K + GFC N++ + L+ KY ++ ID DVHH
Sbjct: 125 HAEKNKAMGFCIYNNVAVGANYLINKYKLKKIAIIDFDVHH 165
>UniRef50_A4YNH4 Cluster: Acetylpolyamine aminohydrolase; n=15;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Bradyrhizobium sp. (strain ORS278)
Length = 374
Score = 46.4 bits (105), Expect = 8e-04
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA + SGFC++N+ IA L + H RV +D+DVHH
Sbjct: 190 HHAYRDIASGFCFMNNSAIAAAHLRQRHERVAILDVDVHH 229
>UniRef50_Q7RB89 Cluster: Histone deacetylase/AcuC/AphA family
protein, putative; n=6; Plasmodium|Rep: Histone
deacetylase/AcuC/AphA family protein, putative -
Plasmodium yoelii yoelii
Length = 461
Score = 46.4 bits (105), Expect = 8e-04
Identities = 25/66 (37%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = +1
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLY 765
G L + L ++ C ++ GG HH+K+ + GFC NDI IA+ LL Y V+
Sbjct: 253 GTILSSLLALKHSMC---MHIGGGNHHSKRDKGDGFCIFNDIAIAVDFLLFYKIVKNVII 309
Query: 766 IDIDVH 783
+D+DVH
Sbjct: 310 LDVDVH 315
>UniRef50_Q02A43 Cluster: Histone deacetylase superfamily; n=1;
Solibacter usitatus Ellin6076|Rep: Histone deacetylase
superfamily - Solibacter usitatus (strain Ellin6076)
Length = 305
Score = 46.0 bits (104), Expect = 0.001
Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 2/126 (1%)
Frame = +1
Query: 415 PYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTG 594
P A+ D+ H +Y+ L+ T SY +D+L + + E F G
Sbjct: 47 PESATDDDVRLVHDPEYVAKLRGGT----LSY-QDILRLEIPYSRQMVEA---FWLAAGG 98
Query: 595 ASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAI--LELLKYHPRVLYI 768
+ L + L + I N GG HHA GFC +ND+ IA+ L+ + R + +
Sbjct: 99 SILAARLALQDG---IGFNIGGGFHHAFPGHGEGFCAINDVAIAVRRLQADRLIKRAMVV 155
Query: 769 DIDVHH 786
D DVHH
Sbjct: 156 DCDVHH 161
>UniRef50_Q8RX28 Cluster: Histone deacetylase 5; n=4;
Magnoliophyta|Rep: Histone deacetylase 5 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 660
Score = 46.0 bits (104), Expect = 0.001
Identities = 37/162 (22%), Positives = 75/162 (46%), Gaps = 7/162 (4%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNI 501
G HP P R+ V + G+ ++ + +A + H++D++ +++++ +
Sbjct: 43 GEDHPECPDRIRVIWEKLQLAGVSQRCVVLGSSKAEDKHLQLVHTKDHVNLVKSISTKQ- 101
Query: 502 QSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNT--CDIAINWSGGLHHA 675
+ Y ++ + + + + G + + G+ ++ A K+ C AI G HHA
Sbjct: 102 KDYRRNRIASQL-NSIYLNGGSSEAAYLAAGSVVKLAEKVAEGELDCGFAIVRPPG-HHA 159
Query: 676 KKFEPSGFCYVNDIVIAILELLKYHP-----RVLYIDIDVHH 786
+ E GFC N++ +A LL P ++L +D DVHH
Sbjct: 160 EADEAMGFCLFNNVAVAASFLLNERPDLGVKKILIVDWDVHH 201
>UniRef50_Q9A2B7 Cluster: Histone deacetylase family protein; n=9;
Alphaproteobacteria|Rep: Histone deacetylase family
protein - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 304
Score = 45.6 bits (103), Expect = 0.001
Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 2/126 (1%)
Frame = +1
Query: 412 KPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYT 591
+P +C HSEDY+ + + S D++ +G P E + T
Sbjct: 48 RPEPVDVETLCLAHSEDYVRGVIEL------SLPPDIVR-RIG--MPNTESVATRARAAT 98
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP--RVLY 765
G +L A IA N +GG HHA +GFC ND+ +A LL + L
Sbjct: 99 GGTLLAARLALER--GIACNTAGGSHHAAADAGAGFCVFNDVAVAARRLLAEGAIGKALV 156
Query: 766 IDIDVH 783
+D+DVH
Sbjct: 157 VDLDVH 162
>UniRef50_Q1IJP8 Cluster: Histone deacetylase superfamily; n=1;
Acidobacteria bacterium Ellin345|Rep: Histone
deacetylase superfamily - Acidobacteria bacterium
(strain Ellin345)
Length = 357
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
Frame = +1
Query: 586 YTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRV 759
+TG ++ A + ++ +A N GG HHA GFC ++D+ +AI +L K RV
Sbjct: 117 HTGGTILAAERALSD--GVAFNLGGGFHHAYPDHGEGFCMIHDVAVAIRKLQKQGRIQRV 174
Query: 760 LYIDIDVH 783
+ +D DVH
Sbjct: 175 MTLDCDVH 182
>UniRef50_Q015Q9 Cluster: Histone deacetylase HDA110 isoform 2; n=2;
Ostreococcus|Rep: Histone deacetylase HDA110 isoform 2 -
Ostreococcus tauri
Length = 487
Score = 45.2 bits (102), Expect = 0.002
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
Frame = +1
Query: 316 HYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQ 495
H GH +P R V + GL + + + A+ ++ R HS++++ F+ + +
Sbjct: 115 HEKDGHFERPARHRVVVNEMRADGLESRCERLRCREATVEELERAHSKEHVAFVASAFDE 174
Query: 496 NIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD--IAINWSGGLH 669
+ +S GDD M G+ E + + D A+ G H
Sbjct: 175 DGESVQIMTGENVFGDDIFFTRHTAAGARMAAGSVSEACLSVCRGDVDRAYAVVRPPG-H 233
Query: 670 HAKKFEPSGFCYVNDIVIAILELLKYH---PRVLYIDIDVHH 786
HA + GFC+ N+ V+A + H +V+ +D DVHH
Sbjct: 234 HAVCAQAMGFCFFNNAVVAARAAMAEHADVKKVVILDWDVHH 275
>UniRef50_Q1N4R7 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Oceanobacter sp. RED65|Rep: Deacetylases, including
yeast histone deacetylase and acetoin utilization
protein - Oceanobacter sp. RED65
Length = 308
Score = 44.8 bits (101), Expect = 0.002
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 5/171 (2%)
Frame = +1
Query: 286 YFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDY 465
+ + D P HP P R + + GL + I + S HS+ Y
Sbjct: 6 FIQHSDFDQHSVPPQHPESPLRNLAVETKLRQSGLWNDLSIEQAKPVSREIFQLIHSKGY 65
Query: 466 IEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKL---NNNTC 636
I+ L N++P K ++ + D P+ + G+ ++ + +
Sbjct: 66 IDQLYNISPP------KGMILAD--PDTPLAFDTLEATEEAAGSGIQAVESILSGKHQNA 117
Query: 637 DIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
AI G HHA+ + GFC+VN+I +A L RVL D DVH
Sbjct: 118 FCAIRPPG--HHAEPKKTKGFCFVNNIALAAQHALNQAGINRVLIFDFDVH 166
>UniRef50_A0KLZ2 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=3; Gammaproteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Aeromonas
hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB
9240)
Length = 319
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/66 (40%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Frame = +1
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLY 765
GA+L + C + I SGG HHA + SGFC ND+VIA L +VL
Sbjct: 115 GATLAASRHALEQGCGLQI--SGGYHHAHRDVGSGFCLFNDLVIAAQVCLDEGRCEQVLI 172
Query: 766 IDIDVH 783
+D+DVH
Sbjct: 173 VDLDVH 178
>UniRef50_UPI0000E87DA7 Cluster: histone deacetylase family protein;
n=1; Methylophilales bacterium HTCC2181|Rep: histone
deacetylase family protein - Methylophilales bacterium
HTCC2181
Length = 346
Score = 44.4 bits (100), Expect = 0.003
Identities = 42/178 (23%), Positives = 76/178 (42%), Gaps = 6/178 (3%)
Frame = +1
Query: 271 QQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
++++A Y+ + G GHP P R+ + + L K I+ + + +
Sbjct: 26 EKKIAVLYDKRMLAHDTGIGHPETPRRIESAYTAIKNDKLLTKHLIWPSIKEVSDTTLQL 85
Query: 451 -HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCS-MYTGASLEGAMKLN 624
H++ YI+ + + + + + + GD V D + + G+ +EG ++
Sbjct: 86 VHTKKYID---QIAKEISTLKATETAYLSTGD--VVISRNSDMAARVAVGSVIEGVNQIM 140
Query: 625 NNTCD--IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
N A+ G HHA + GFC N+I IA L + R+L +D DVHH
Sbjct: 141 TNVASSAFALVRPPG-HHASSDKGMGFCIYNNIAIAARYLQQQFGLERILIVDFDVHH 197
>UniRef50_Q8EFZ9 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=10; Proteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Shewanella
oneidensis
Length = 304
Score = 44.4 bits (100), Expect = 0.003
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 3/130 (2%)
Frame = +1
Query: 403 QIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFD-FC 579
Q + P +A ++ + H DY+E Q I +G P E L +
Sbjct: 43 QFHTPTPMTAEEIMQVHHRDYVE-------QFIDGTLATSALRRIG--FPWSEALVERTL 93
Query: 580 SMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELL--KYHP 753
G SL A+ L IA++ +GG HHA SG+C ND++IA +L+ +
Sbjct: 94 HSLAGTSLTAALALQTG---IALHLTGGYHHAHYEFGSGYCIFNDLIIAARKLIIEQQLH 150
Query: 754 RVLYIDIDVH 783
++L D DVH
Sbjct: 151 KILIFDCDVH 160
>UniRef50_Q1IMW0 Cluster: Histone deacetylase superfamily; n=2;
Acidobacteria|Rep: Histone deacetylase superfamily -
Acidobacteria bacterium (strain Ellin345)
Length = 298
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/45 (51%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +1
Query: 655 SGGLHHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVH 783
+GG HHA + E SG+C NDI IAIL L R ID+DVH
Sbjct: 113 AGGTHHAFRSEGSGYCVFNDIAIAILYLRSKGLAQRAAVIDLDVH 157
>UniRef50_A5W9E9 Cluster: Histone deacetylase superfamily; n=17;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Pseudomonas putida F1
Length = 317
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Frame = +1
Query: 592 GASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIA---ILELLKYHPRVL 762
G+ L M L + IA + +GG HHA P+GFC ND+ + +LE + H RVL
Sbjct: 111 GSLLTAEMALQHG---IACHLAGGTHHAHYDHPAGFCIFNDLAVISRYLLEAGRVH-RVL 166
Query: 763 YIDIDVH 783
D DVH
Sbjct: 167 IFDCDVH 173
>UniRef50_Q5KNI3 Cluster: Histone deacetylase, putative; n=2;
Filobasidiella neoformans|Rep: Histone deacetylase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 541
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/42 (47%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH + PSGFCYVN++VI L H R + ID D+HH
Sbjct: 232 HHCGEDAPSGFCYVNNVVIGALHGYLQHDIDRAIIIDFDLHH 273
>UniRef50_A6C2D6 Cluster: Deacetylase; n=1; Planctomyces maris DSM
8797|Rep: Deacetylase - Planctomyces maris DSM 8797
Length = 319
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAIL-----ELLKYHPRVLYIDIDVH 783
+AIN SGG HH+K + GFC D IA+ L+ R++Y+D D H
Sbjct: 121 LAINLSGGYHHSKPAQGEGFCVYADAAIAVATLRQQALISETDRIVYVDTDAH 173
>UniRef50_Q6C4P0 Cluster: Similar to sp|P53973 Saccharomyces
cerevisiae YNL021w HDA1 histone deacetylase A; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P53973
Saccharomyces cerevisiae YNL021w HDA1 histone
deacetylase A - Yarrowia lipolytica (Candida lipolytica)
Length = 748
Score = 44.0 bits (99), Expect = 0.004
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 7/128 (5%)
Frame = +1
Query: 424 ASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEG-LFDFCSMYTGAS 600
AS ++ H+ +++FL + N LL D F F + G +
Sbjct: 159 ASLDEVLEVHTPAHVDFLASTEKMN----RPQLLEEGEKGDSVYFNNESFSAGKLSCGGT 214
Query: 601 LEGAMKL--NNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP----RVL 762
+E + N IA+ G HHA+ P+GFC +++ +A LLK +P R+L
Sbjct: 215 IETCRAVIERNVKNAIAVVRPPG-HHAEPGNPAGFCMFSNVAVAAKVLLKRYPERVKRIL 273
Query: 763 YIDIDVHH 786
+D DVHH
Sbjct: 274 ILDWDVHH 281
>UniRef50_A5DRS6 Cluster: Histone deacetylase HDA1; n=7;
Saccharomycetales|Rep: Histone deacetylase HDA1 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 906
Score = 44.0 bits (99), Expect = 0.004
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 9/130 (6%)
Frame = +1
Query: 424 ASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKD--LLHYNVGDDCPVFEGLFDFCSMYTGA 597
A+ ++ HSE ++E +Q+ ++ +KD L GD V + + G
Sbjct: 270 ATIEEILEVHSEKHLEHIQST-----ETMTKDELLRETATGDSIYVNNDSYFSAKLSCGG 324
Query: 598 SLEGAMKLNNNTCD---IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP----R 756
++E + A+ G HHA+ +P GFC +++ +A +LK +P R
Sbjct: 325 TIEACKAVIEGRVKNSLAAVRPPG--HHAEPDDPGGFCLFSNVAVAAKNILKSYPESVRR 382
Query: 757 VLYIDIDVHH 786
++ +D D+HH
Sbjct: 383 IVILDWDIHH 392
>UniRef50_Q2LVD3 Cluster: Histone deacetylase family protein; n=1;
Syntrophus aciditrophicus SB|Rep: Histone deacetylase
family protein - Syntrophus aciditrophicus (strain SB)
Length = 350
Score = 43.6 bits (98), Expect = 0.006
Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 4/159 (2%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNI 501
GPGHP P RL V + ++ + + Q A ++ H DY+ + +
Sbjct: 18 GPGHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLIHLPDYVNRVASTARMEY 77
Query: 502 QSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD--IAINWSGGLHHA 675
D D P G + + G E + + D A+ G HHA
Sbjct: 78 SCLDPDT------DTSP---GSYKAALLAAGGLCEAISMVASGKLDNAFALVRPPG-HHA 127
Query: 676 KKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
+ GFC N++ I + + R+L ID D+HH
Sbjct: 128 EADRSKGFCLFNNVAIGARYAQTALHLQRILIIDWDLHH 166
>UniRef50_A5D0K9 Cluster: Deacetylases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Deacetylases - Pelotomaculum
thermopropionicum SI
Length = 355
Score = 43.6 bits (98), Expect = 0.006
Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 2/159 (1%)
Frame = +1
Query: 316 HYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQ 495
H G P P R+ T+ ++ G+ +K+ KP A+ ++ H YIE ++ + +
Sbjct: 22 HETHGCPESPARVKHTYEILKIAGMLEKLVTIKPRPATVEEVSLVHLPAYIERVKEFSKR 81
Query: 496 NIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHA 675
S+ N FE + T +++E ++ + + G HHA
Sbjct: 82 GGGSFGN-----NTTGSPETFETAL-LAAGGTLSAVEAVLEGRVESAFALVRPPG--HHA 133
Query: 676 KKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+ + G+C+ N+ IA +K + RVL ID D HH
Sbjct: 134 RPGQAMGYCFFNNAAIAARYAIKRYGLSRVLIIDWDEHH 172
>UniRef50_Q7XAX9 Cluster: HDA1; n=3; Magnoliophyta|Rep: HDA1 - Zea
mays (Maize)
Length = 701
Score = 43.6 bits (98), Expect = 0.006
Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 7/162 (4%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNI 501
G HP P RL + G+ + K A + HS+ +I+ ++ ++ I
Sbjct: 31 GEEHPENPERLRSIWRKLNAAGVASRCVALKAKEAEDKYIASVHSKRHIKLMKEIS-STI 89
Query: 502 QSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKL--NNNTCDIAINWSGGLHHA 675
S++ + + + +G + + G+ +E A K+ + IA+ G HHA
Sbjct: 90 YDASRNKIARKF-NSIYLNKGSSESAVLAAGSVIEVAEKVAAGELSSAIALVRPPG-HHA 147
Query: 676 KKFEPSGFCYVNDIVIAILELLKYHP-----RVLYIDIDVHH 786
+ E GFC N++ +A LL P ++L +D DVHH
Sbjct: 148 EHDEAMGFCLFNNVAVAANYLLNERPDLGIKKILIVDWDVHH 189
>UniRef50_Q9VC26 Cluster: CG31119-PA; n=5; Diptera|Rep: CG31119-PA -
Drosophila melanogaster (Fruit fly)
Length = 343
Score = 43.6 bits (98), Expect = 0.006
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Frame = +1
Query: 409 YKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMY 588
Y+P + + R H+ +Y++ L+ N+ ++ L V + L
Sbjct: 77 YEPTELTKDQLRRIHTREYLKSLR--WSMNVACIAEVPLMAFVPNRYIQRSYLRPMRFQA 134
Query: 589 TGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP----R 756
G+ L G + L+ AIN GG HH + GFC DI + I+ L + P R
Sbjct: 135 AGSILAGKLALDYGW---AINLGGGFHHCCSYRGGGFCPYADISLLIVRLFEQEPFRVRR 191
Query: 757 VLYIDIDVH 783
++ +D+D H
Sbjct: 192 IMIVDLDAH 200
>UniRef50_UPI0000D56143 Cluster: PREDICTED: similar to CG6170-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6170-PA, isoform A - Tribolium castaneum
Length = 824
Score = 43.2 bits (97), Expect = 0.008
Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVHH 786
HHA + E +G+CY N++ IA +L+ + RV+ +D DVHH
Sbjct: 184 HHAMENEYNGYCYFNNVAIAAESVLREGHSKRVMIVDFDVHH 225
Score = 42.7 bits (96), Expect = 0.010
Identities = 20/42 (47%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELL-KYH-PRVLYIDIDVHH 786
HHA+ + G+C+VN+I +A LL KY RVL +D D+HH
Sbjct: 588 HHAEHDKAMGYCFVNNIAVAANYLLDKYEVERVLIVDFDIHH 629
>UniRef50_Q4TFH7 Cluster: Chromosome undetermined SCAF4471, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4471,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1260
Score = 43.2 bits (97), Expect = 0.008
Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 6/158 (3%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
HP P R+ + GL + +P A+ ++ H++ +++ L++ Q+
Sbjct: 94 HPESPERVTFIMEELQHQGLLSQCTRVEPREATEEELLLCHTKHHVDLLRST-----QTM 148
Query: 511 SKDLLHYNVGDDCPVFEGLFDFCSMYT--GASLEGAMKLNNNTC--DIAINWSGGLHHAK 678
++D LH V+ F + T G+ L+ ++ + A+ G HHA+
Sbjct: 149 TEDELHSLSDKYDSVYLHPESFTAGVTAVGSLLQLVDRVMTSELRNGFAVVRPPG-HHAQ 207
Query: 679 KFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
K P+GFC N++ IA H RVL +D DVHH
Sbjct: 208 KDLPNGFCLFNNVAIAARYAQTRHSVSRVLIVDWDVHH 245
Score = 35.1 bits (77), Expect = 2.0
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP----RVLYIDIDVHH 786
HHA++ P GFC+ N +A K RVL +D DVHH
Sbjct: 683 HHAERDLPCGFCFFNTAALAARHAQKLSRDAPLRVLILDWDVHH 726
>UniRef50_Q62HN7 Cluster: Acetylpolyamine aminohydrolase; n=53;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Burkholderia mallei (Pseudomonas mallei)
Length = 340
Score = 43.2 bits (97), Expect = 0.008
Identities = 18/40 (45%), Positives = 23/40 (57%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA+ GFCY+N+ IA L H RV +D D+HH
Sbjct: 155 HHARVDAAGGFCYLNNAAIAAQALRARHARVAVLDTDMHH 194
>UniRef50_P28606 Cluster: Uncharacterized 34.1 kDa protein in glnA
3'region; n=15; Cyanobacteria|Rep: Uncharacterized 34.1
kDa protein in glnA 3'region - Synechococcus sp. (strain
PCC 7002) (Agmenellum quadruplicatum)
Length = 310
Score = 43.2 bits (97), Expect = 0.008
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVH 783
+A N +GG HHA SGFC +ND+ IA ++ R+L +D+DVH
Sbjct: 121 LACNTAGGTHHAFPGYGSGFCILNDLAIATRTIQQRGLAQRILIVDLDVH 170
>UniRef50_Q4RSK1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF15000, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 411
Score = 42.7 bits (96), Expect = 0.010
Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 4/152 (2%)
Frame = +1
Query: 343 PHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDL 522
P RL V + + GL + A+ D+ HSE+Y+E ++ + +
Sbjct: 28 PERLKVCAEALKRTGLADRCVSVPVREATDADILLAHSEEYLEAVKKTPYMTLGDLMEFT 87
Query: 523 LHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC--DIAINWSGGLHHAKKFEPSG 696
L Y D ++ + GA+L+ + +A+ G HH+ + +G
Sbjct: 88 LQYG---DVYFHPNIYHCAKLAAGAALQLVDSVMTGAVRNGMALVRPPG-HHSMRSAANG 143
Query: 697 FCYVNDIVIAI-LELLKYH-PRVLYIDIDVHH 786
FC N++ IA KY RVL +D DVHH
Sbjct: 144 FCVFNNVAIAARYAKQKYSLQRVLIVDWDVHH 175
>UniRef50_Q3ZWU5 Cluster: Histone deacetylase family protein; n=3;
Dehalococcoides|Rep: Histone deacetylase family protein
- Dehalococcoides sp. (strain CBDB1)
Length = 341
Score = 42.7 bits (96), Expect = 0.010
Identities = 43/172 (25%), Positives = 65/172 (37%), Gaps = 3/172 (1%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSE 459
V YN N G H P RL + +GL ++ +P R ++ FH
Sbjct: 3 VGLVYNHIYLNHDTGT-HVENPDRLLAIMEYLETHGLKDRLVHIEPKRVGMRELESFHKR 61
Query: 460 DYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD 639
YI ++ V +S + D + ++ G +EG K+ + D
Sbjct: 62 SYISRVEEV------GFSGGGW---LDQDTVISLDSYEAALYAVGGVIEGVDKVLSRELD 112
Query: 640 IA-INWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
A + HHA GFC N++ + L L H RV +D DVHH
Sbjct: 113 SAFVLCRPPGHHALPEASMGFCVFNNVALGALHALNKHKLKRVAVVDFDVHH 164
>UniRef50_A2WM81 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 156
Score = 42.7 bits (96), Expect = 0.010
Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 12/73 (16%)
Frame = +1
Query: 445 RFHSEDYIEFLQNVTPQNIQSYSKDLL-------HYNVG-----DDCPVFEGLFDFCSMY 588
RFH +YI+ ++N+TP+ SY+ D++ + +G +DCP F L+ +C Y
Sbjct: 16 RFHLPEYIDLIRNLTPE---SYANDVVLRQKAEDDHGIGLLGDDNDCPAFNRLWKYCRGY 72
Query: 589 TGASLEGAMKLNN 627
G SL A L N
Sbjct: 73 AGGSLAAARALVN 85
>UniRef50_A6SGS8 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 780
Score = 42.7 bits (96), Expect = 0.010
Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Frame = +1
Query: 373 VLKYGLHKKMQIYKPYRASAHDMCRFHSE---DYIEFLQNVTPQNIQSYSKDLLHYNVG- 540
+LK +K MQ A ++C H+ D++E L ++T + ++ ++ Y+ G
Sbjct: 140 ILKESPNKYMQRIMARLARKDEICLAHTAFHYDWVESLLSMTSEELREANQ---RYDTGR 196
Query: 541 DDCPVFEGLFDFCSMYTGASLEGA--MKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVND 714
V +D + G ++E + + N IAI G HHA++ E GFC N+
Sbjct: 197 KSLYVGPCTYDAALVAAGGAIETCKHVVVGNVKNAIAIIRPPG-HHAEENEALGFCVFNN 255
Query: 715 IVIAILELLKYHP----RVLYIDIDVHH 786
+ IA + +P +VL +D D+HH
Sbjct: 256 VPIAAKVCMADYPEICRKVLILDWDIHH 283
>UniRef50_Q569C4 Cluster: Histone deacetylase 10; n=5; Mammalia|Rep:
Histone deacetylase 10 - Rattus norvegicus (Rat)
Length = 588
Score = 42.7 bits (96), Expect = 0.010
Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 6/154 (3%)
Frame = +1
Query: 343 PHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDL 522
P RL + + GL ++ Q AS ++ HS +YI +Q Q+ K+
Sbjct: 28 PERLTAALDGLRQRGLEERCQCLSVCEASEEELGLVHSPEYIALVQKT-----QTLDKEE 82
Query: 523 LH-YNVGDDCPVFE-GLFDFCSMYTGASLE--GAMKLNNNTCDIAINWSGGLHHAKKFEP 690
LH + D F F + GA+L A+ +A+ G HH+++
Sbjct: 83 LHTLSKQYDAVYFHPDTFHCARLAAGAALRLVDAVLTGAVHNGVALVRPPG-HHSQRAAA 141
Query: 691 SGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+GFC N++ IA + + R+L +D DVHH
Sbjct: 142 NGFCVFNNVAIAARHAKQKYGLQRILIVDWDVHH 175
>UniRef50_UPI0001555A7F Cluster: PREDICTED: similar to histone
deacetylase 6, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to histone deacetylase
6, partial - Ornithorhynchus anatinus
Length = 803
Score = 42.3 bits (95), Expect = 0.013
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 7/177 (3%)
Frame = +1
Query: 277 RVAYFYNPDVGNFH--YGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRF 450
R Y+P + + + HP P R++ + GL ++ + AS ++
Sbjct: 296 RTGLVYDPTMMEHYNMWDSHHPELPQRISRIAQRHAELGLTQRCRALPARLASDQELLLC 355
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGA--SLEGAMKLN 624
HS +Y+E ++ + + ++ YN + F + G+ SL A+
Sbjct: 356 HSPEYVEQMRATSGLKPRELHREGERYN---SIYIAPRSFHCAQLAAGSACSLVEAVLDG 412
Query: 625 NNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAI--LELLKYHP-RVLYIDIDVHH 786
+AI G HHA++ GFC+ N + +A + L P RVL +D DVHH
Sbjct: 413 QVRNGVAIVRPPG-HHAERDTACGFCFFNSVAVAARHAQQLAGRPLRVLILDWDVHH 468
Score = 34.7 bits (76), Expect = 2.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA++ G+C N + ++ + H RVL +D DVHH
Sbjct: 129 HHAQRERMDGYCMFNHLAVSARHAQEKHQVERVLIVDWDVHH 170
>UniRef50_Q569T0 Cluster: MGC115178 protein; n=5; Tetrapoda|Rep:
MGC115178 protein - Xenopus laevis (African clawed frog)
Length = 683
Score = 42.3 bits (95), Expect = 0.013
Identities = 41/155 (26%), Positives = 72/155 (46%), Gaps = 7/155 (4%)
Frame = +1
Query: 343 PHRLAVTHCLVLKYGLHKKMQIYKPYR-ASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKD 519
P RL+ ++ + Y L K+ I P R A+ ++ HS DY++ +++ N + +
Sbjct: 30 PERLSSSYKRLQDYDLVKRC-IQLPVREATDEEITLVHSHDYLQVVKSTQTMNEKELKEI 88
Query: 520 LLHYNVGDDCPVF--EGLFDFCSMYTGASLE--GAMKLNNNTCDIAINWSGGLHHAKKFE 687
Y VF + F + G +L+ A+ +AI G HH+++ +
Sbjct: 89 SQKYTA-----VFYHQNSFRCAKLSLGGTLQLVDAILTREVQNGMAIVRPPG-HHSQRNQ 142
Query: 688 PSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+GFC N++ IA K + R+L +D DVHH
Sbjct: 143 GNGFCVFNNVAIAAEYAKKKYKLERILIVDWDVHH 177
>UniRef50_Q15WQ0 Cluster: Histone deacetylase superfamily; n=3;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 306
Score = 42.3 bits (95), Expect = 0.013
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Frame = +1
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP--RVLYIDIDVH 783
A+N +GG HHA SGFC ND+ +A L +L+ +VL D DVH
Sbjct: 118 ALNLTGGYHHAFANFGSGFCLFNDLYLAALNVLQTPTIRKVLIFDCDVH 166
>UniRef50_A4JTS4 Cluster: Histone deacetylase superfamily; n=3;
Bacteria|Rep: Histone deacetylase superfamily -
Burkholderia vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 376
Score = 42.3 bits (95), Expect = 0.013
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
HP R A L+ G++ + +P A+ D+ RFH+ +Y++ ++ ++
Sbjct: 40 HPDSKRRFAE---LISVSGMNDHLVNIRPELATREDLLRFHTPEYVDKIRTLSEGR---- 92
Query: 511 SKDLLHYNVGDDCPVFEGLFDFCSMYTGA--SLEGAMKLNNNTCDIAINWSGGLHHAKKF 684
G+ P G ++ + TG SL ++ + ++N G HHA
Sbjct: 93 -----GGEAGEHTPFGPGGYEIACLSTGGCISLLESVYRGDVRNGYSLNRPPG-HHAVAD 146
Query: 685 EPSGFCYVNDIVIAI--LELLKYHPRVLYIDIDVHH 786
+ GFC + V+AI L+ + RV +D DVHH
Sbjct: 147 QGRGFCIFGNGVVAIRRLQAMTGVKRVAVVDWDVHH 182
>UniRef50_Q944K3 Cluster: Histone deacetylase 2; n=7;
Magnoliophyta|Rep: Histone deacetylase 2 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 387
Score = 42.3 bits (95), Expect = 0.013
Identities = 41/154 (26%), Positives = 59/154 (38%), Gaps = 3/154 (1%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQN-VTPQNIQS 507
HP + ++ G ++ I +P AS D+ HSE+Y+ L++ T I
Sbjct: 93 HPFDSSKWGRVCKFLVSDGFLEEKAIVEPLEASKIDLLVVHSENYLNSLKSSATVARITE 152
Query: 508 YSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFE 687
+ N V L+ F G L + AIN GG HH
Sbjct: 153 VAPVAFFPNFLVQQKV---LYPFRKQVGGTILAAKLATERGW---AINIGGGFHHCTAER 206
Query: 688 PSGFCYVNDIVIAI-LELLKYH-PRVLYIDIDVH 783
GFC DI + I L+ RV+ ID+D H
Sbjct: 207 GGGFCAFADISLCIHFAFLRLRISRVMIIDLDAH 240
>UniRef50_Q3IF01 Cluster: Putative histone deacetylase family
protein; n=3; Alteromonadales|Rep: Putative histone
deacetylase family protein - Pseudoalteromonas
haloplanktis (strain TAC 125)
Length = 306
Score = 41.9 bits (94), Expect = 0.018
Identities = 42/172 (24%), Positives = 65/172 (37%), Gaps = 2/172 (1%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHS 456
R A +P HP P RL + +L GL ++ + +A H
Sbjct: 2 RTAIISHPHCRKHKMIDDHPECPERLDAINDRLLASGLDIAIEQKQAPKAQREHYLLAHD 61
Query: 457 EDYIEFLQNVTP-QNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNT 633
E + F+++ P Q + D + D E + LEG N +
Sbjct: 62 ESLVSFVESKIPTQGLVDLDGDT--WLCPDSLKAIERAVGAGILAVDEILEG----NLDA 115
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAI-LELLKYHPRVLYIDIDVHH 786
++ G HHA + SGFC N++ IA+ K R+ +D DVHH
Sbjct: 116 AFCSVRPPG--HHANRTTSSGFCVFNNLAIAVKYAQSKGVKRIAIVDFDVHH 165
>UniRef50_Q18477 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 282
Score = 41.9 bits (94), Expect = 0.018
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Frame = +1
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAILELL--KYHPRVLYIDIDVH 783
AIN GG HHA GFC+ DI +AI +L K + +D+D H
Sbjct: 83 AINVGGGFHHASHSGGGGFCFYADITMAIFDLFDKKAIANAIVVDLDAH 131
>UniRef50_Q5KL48 Cluster: Histone deacetylase clr3, putative; n=1;
Filobasidiella neoformans|Rep: Histone deacetylase clr3,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 737
Score = 41.9 bits (94), Expect = 0.018
Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 8/173 (4%)
Frame = +1
Query: 292 YNPDVGN-FHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSE--- 459
Y P N G GHP P R+ + + GL ++M+ + H E
Sbjct: 77 YMPTAENVMDNGDGHPEDPMRIKRIFTRLAEQGLIRRMKRLDFEEVKFEQVLLVHGEEMW 136
Query: 460 DYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD 639
D ++ + ++ Q IQ D+ Y V + G ++ + N
Sbjct: 137 DKVQATELLSDQQIQ----DMKEYYDQLSLYVCRETAHCARLSAGGVIQACRSVCKNEVR 192
Query: 640 --IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVHH 786
AI G HHA+ E GFC+ N++ +A E+ + +VL +D DVHH
Sbjct: 193 NAFAIVRPPG-HHAEPNEHMGFCFFNNVAVATREMQREGLAKKVLILDWDVHH 244
>UniRef50_A0B6D0 Cluster: Histone deacetylase superfamily; n=1;
Methanosaeta thermophila PT|Rep: Histone deacetylase
superfamily - Methanosaeta thermophila (strain DSM 6194
/ PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 284
Score = 41.9 bits (94), Expect = 0.018
Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Frame = +1
Query: 592 GASLEGAMKLNNNTCDIAINWSGGL-HHAKKFEPSGFCYVNDIVIAILELLKYH-PRVLY 765
G+ L A + + + A ++G HHA + GFCY ND+ I IL+L K R L
Sbjct: 83 GSVLMAAELVVSGKAESAFAYTGTAGHHASRGSCWGFCYFNDVAITILKLRKMGLKRFLI 142
Query: 766 IDIDVH 783
ID+D H
Sbjct: 143 IDVDPH 148
>UniRef50_P53973 Cluster: Histone deacetylase HDA1; n=7;
Saccharomycetales|Rep: Histone deacetylase HDA1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 706
Score = 41.9 bits (94), Expect = 0.018
Identities = 38/188 (20%), Positives = 79/188 (42%), Gaps = 18/188 (9%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKK-----------MQIYKPYR 423
R+ Y F Y HP P R+ + ++ + GL + + P R
Sbjct: 65 RMRYHAKIFTSYFEYIDPHPEDPRRIYRIYKILAENGLINDPTLSGVDDLGDLMLKIPVR 124
Query: 424 AS-AHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGAS 600
A+ + ++ H+++++EF+++ + + K+ GD + + G +
Sbjct: 125 AATSEEILEVHTKEHLEFIESTEKMSREELLKET---EKGDSVYFNNDSYASARLPCGGA 181
Query: 601 LEGAMKLNNNTC--DIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP----RVL 762
+E + +A+ G HHA+ GFC +++ +A +LK +P R++
Sbjct: 182 IEACKAVVEGRVKNSLAVVRPPG-HHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIM 240
Query: 763 YIDIDVHH 786
+D D+HH
Sbjct: 241 ILDWDIHH 248
>UniRef50_UPI000065FABE Cluster: Histone deacetylase 6 (HD6).; n=1;
Takifugu rubripes|Rep: Histone deacetylase 6 (HD6). -
Takifugu rubripes
Length = 1154
Score = 41.5 bits (93), Expect = 0.023
Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSY 510
HP +P R+A + + L ++ +P R + ++ HS+ Y++ +++ Q+
Sbjct: 63 HPERPERVASIMEHLEQQDLLSRVTRVQP-REATEELLLCHSQHYVDLMKST-----QTM 116
Query: 511 SKDLLHY--NVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC--DIAINWSGGLHHAK 678
+++ LH + D + F M G+ L+ ++ + A+ G HHA+
Sbjct: 117 TEEELHSLSDKYDSIYLHPESFSVAVMAVGSVLQLVDQVMTSELRNGFAVVRPPG-HHAQ 175
Query: 679 KFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
K P+GF N++ IA H RVL +D DVHH
Sbjct: 176 KDLPNGFSIFNNVAIAARYAQTRHSVSRVLIVDWDVHH 213
Score = 33.5 bits (73), Expect = 6.2
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP----RVLYIDIDVHH 786
HHA++ P GFC+ N +A K VL +D DVHH
Sbjct: 589 HHAERDFPCGFCFFNTAALAARHAQKLSQDAPLHVLILDWDVHH 632
>UniRef50_A6VZD7 Cluster: Histone deacetylase superfamily; n=2;
Marinomonas|Rep: Histone deacetylase superfamily -
Marinomonas sp. MWYL1
Length = 308
Score = 41.5 bits (93), Expect = 0.023
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELL--KYHPRVLYIDIDVH 783
+A + +GG HHA SGFC ND+ +A L ++ ++L +D DVH
Sbjct: 114 LACHLAGGTHHAHPSHGSGFCIFNDLAVAALAMIGSGRAKKILILDCDVH 163
>UniRef50_A5WHG1 Cluster: Histone deacetylase superfamily; n=17;
Bacteria|Rep: Histone deacetylase superfamily -
Psychrobacter sp. PRwf-1
Length = 302
Score = 41.5 bits (93), Expect = 0.023
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVH 783
+++N +GG HHA GFC ND+ IA LL ++L +D+DVH
Sbjct: 110 VSLNVAGGTHHAFADHGEGFCVFNDVCIASNLLLSRGQASKILIVDLDVH 159
>UniRef50_A5VD94 Cluster: Histone deacetylase superfamily; n=6;
Alphaproteobacteria|Rep: Histone deacetylase superfamily
- Sphingomonas wittichii RW1
Length = 315
Score = 41.5 bits (93), Expect = 0.023
Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Frame = +1
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAILELL--KYHPRVLYIDIDVH 783
A N +GG HHA +G+C ND+ IA L+ + R++ +D+DVH
Sbjct: 109 AANGAGGSHHAMADSGAGYCVFNDLAIAANRLIVERDAARIMIVDLDVH 157
>UniRef50_A3JI99 Cluster: Putative aminohydrolase; n=1; Marinobacter
sp. ELB17|Rep: Putative aminohydrolase - Marinobacter
sp. ELB17
Length = 344
Score = 41.5 bits (93), Expect = 0.023
Identities = 19/55 (34%), Positives = 28/55 (50%)
Frame = +1
Query: 622 NNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
+ N I + G HHA+K GFCY+N+ I L + ++ ID D+HH
Sbjct: 146 HQNDIQICLTRPAG-HHARKSAAGGFCYLNNAAIIAEHLRQKFQKIAIIDTDMHH 199
>UniRef50_Q64BV4 Cluster: Acetoin utilization protein; n=5;
Archaea|Rep: Acetoin utilization protein - uncultured
archaeon GZfos26F9
Length = 351
Score = 41.5 bits (93), Expect = 0.023
Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 5/178 (2%)
Frame = +1
Query: 268 TQQRVAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCR 447
T + Y+ D G HP RL + + G+ +K++ P +AS +
Sbjct: 3 TTTSTGFVYHEDYLKHDTGV-HPETAERLRAIIRKLEETGIAEKLRRIIPTKASKEQLRY 61
Query: 448 FHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGA---MK 618
H+ +YIE ++ + + + + D P+ E ++ + TG + M
Sbjct: 62 VHAPEYIEEVEAMCRRGGGA---------LDPDTPLCEATYEIALLATGGVTKAGDEVMD 112
Query: 619 LNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+N+ + HHA + GFC N+I IA L + + RVL D DVHH
Sbjct: 113 ESNSLKHVFALIRPPGHHATPNKGMGFCIFNNIAIATEHLKREYGINRVLIADWDVHH 170
>UniRef50_Q08BS8 Cluster: Zgc:152701; n=9; Euteleostomi|Rep:
Zgc:152701 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1023
Score = 41.1 bits (92), Expect = 0.031
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
HHA++ P GFCY N + IA +L+ ++L +D DVHH
Sbjct: 741 HHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHH 782
>UniRef50_Q6AKN4 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 341
Score = 41.1 bits (92), Expect = 0.031
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 5/134 (3%)
Frame = +1
Query: 400 MQIYKPYRASAHDMCRFHSEDYI-EFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDF 576
++I P+ A+ + + HS Y+ + ++ N SY +D + +
Sbjct: 43 LRIITPHEANTETIEKVHSNFYLSQIREHALKSNPFSYDQDTY---------LMQQSLAT 93
Query: 577 CSMYTGASLEGAMKLNNNTCD--IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH 750
+ G LE A ++ N D A+ G HHA+ GFC +N+I I L ++
Sbjct: 94 AQLAAGGCLEIADQIMNGEIDHGFALIRPPG-HHAEPGRGMGFCILNNIAITAKYLQTHY 152
Query: 751 --PRVLYIDIDVHH 786
R+L ID DVHH
Sbjct: 153 NLSRILIIDFDVHH 166
>UniRef50_P72702 Cluster: Uncharacterized protein slr0245; n=15;
Cyanobacteria|Rep: Uncharacterized protein slr0245 -
Synechocystis sp. (strain PCC 6803)
Length = 304
Score = 41.1 bits (92), Expect = 0.031
Identities = 44/174 (25%), Positives = 69/174 (39%), Gaps = 5/174 (2%)
Frame = +1
Query: 280 VAYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAH---DMCRF 450
VA Y+ + GP HP P RL + K + KP + + + R
Sbjct: 2 VAIIYSAEFLRHETGPTHPECPARLTAIATALRKMPGANYLHWQKPSPVTWNLDPYILRC 61
Query: 451 HSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNN 630
HS++Y+ L + +L ++ D PV +D + A L+G + N
Sbjct: 62 HSQEYLNKLAKLA---------ELGGGSLDADTPVSPQSYDVARLAVRAWLDGVDHVLNQ 112
Query: 631 TCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+ + HHA + GFC +N++ IA L RV +D DVHH
Sbjct: 113 REAVFVLARPPGHHAIRNTGMGFCLLNNVAIAAHYALTRPGVERVAILDWDVHH 166
>UniRef50_Q4SMC8 Cluster: Chromosome 3 SCAF14553, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 3
SCAF14553, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1155
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
HHA++ P GFCY N + IA +L+ ++L +D DVHH
Sbjct: 847 HHAEESTPMGFCYFNSVAIAAKLLQQRLNINKILIVDWDVHH 888
>UniRef50_Q1H193 Cluster: Histone deacetylase superfamily; n=2;
Betaproteobacteria|Rep: Histone deacetylase superfamily
- Methylobacillus flagellatus (strain KT / ATCC 51484 /
DSM 6875)
Length = 307
Score = 40.7 bits (91), Expect = 0.041
Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 4/156 (2%)
Frame = +1
Query: 331 HPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQ-NIQS 507
HP P R+ + ++ L K+Q ++ +A+ + R H YI+ ++++ P+ I
Sbjct: 20 HPESPARITAIMDALAEHRLLDKLQRHEAPQATDEALLRVHDAAYIKHIRSIAPRAGIVR 79
Query: 508 YSKDLLHYNVG-DDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKF 684
D + C G ++ L ++ N C + G HHA +
Sbjct: 80 LDPDTAMGPMSLSACLHASG-----AVIKAVDLVMQKQVTNAFC--CVRPPG--HHAGRA 130
Query: 685 EPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+GFC N I + L + R+ +DIDVHH
Sbjct: 131 RAAGFCIFNHIAAGVAYALASYKLKRIAVLDIDVHH 166
>UniRef50_A6G5J4 Cluster: Histone deacetylase superfamily protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Histone
deacetylase superfamily protein - Plesiocystis pacifica
SIR-1
Length = 274
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/40 (45%), Positives = 25/40 (62%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA++ G+CY N+ IA EL + RV+ +DID HH
Sbjct: 84 HHAEEDMFGGYCYFNNSAIAARELRQGGARVVVLDIDFHH 123
>UniRef50_A0Z891 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1; marine
gamma proteobacterium HTCC2080|Rep: Deacetylases,
including yeast histone deacetylase and acetoin
utilization protein - marine gamma proteobacterium
HTCC2080
Length = 304
Score = 40.7 bits (91), Expect = 0.041
Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA+ P GFC +N + IA + LK +V +D DVHH
Sbjct: 123 HHAEHNSPMGFCLLNSVAIAAINALKISGIRKVAILDFDVHH 164
>UniRef50_Q00U49 Cluster: Histone deacetylase superfamily; n=3;
Ostreococcus|Rep: Histone deacetylase superfamily -
Ostreococcus tauri
Length = 749
Score = 40.7 bits (91), Expect = 0.041
Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 5/52 (9%)
Frame = +1
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAIL-----ELLKYHPRVLYIDIDVH 783
A +GG HHA + GFC NDI AI ELL ++L ID+DVH
Sbjct: 554 AAQLAGGTHHAYRDRGEGFCVFNDIGTAIRVVQRDELLPRDRKILVIDLDVH 605
>UniRef50_P56523 Cluster: Histone deacetylase clr3; n=1;
Schizosaccharomyces pombe|Rep: Histone deacetylase clr3
- Schizosaccharomyces pombe (Fission yeast)
Length = 687
Score = 40.7 bits (91), Expect = 0.041
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP----RVLYIDIDVHH 786
HHA+ +P GFC N++ + +L+ P RVL +D D+HH
Sbjct: 194 HHAEPHKPGGFCLFNNVSVTARSMLQRFPDKIKRVLIVDWDIHH 237
>UniRef50_Q7ZYF0 Cluster: Hdac6-prov protein; n=2; Xenopus|Rep:
Hdac6-prov protein - Xenopus laevis (African clawed
frog)
Length = 1286
Score = 40.3 bits (90), Expect = 0.054
Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 4/155 (2%)
Frame = +1
Query: 334 PMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYS 513
P P R+ + +YGL ++ AS ++ HS Y+ +++ +
Sbjct: 101 PECPGRIWAVRDKMAEYGLAERCVAVPAREASEEEILLIHSPQYVALMRSTQKMTMDELR 160
Query: 514 KDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC--DIAINWSGGLHHAKKFE 687
Y D + F S+ G+ L+ ++ + +A+ G HHA +
Sbjct: 161 ALSDRY---DSVYLHPTSFTCASLAVGSVLQLVDRVQHGEIRNGLAVVRPPG-HHAHTDQ 216
Query: 688 PSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
+G+C N + IA +L RVL +D DVHH
Sbjct: 217 MNGYCMFNQLAIAARYAQLTYGAKRVLIVDWDVHH 251
Score = 33.5 bits (73), Expect = 6.2
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 6/46 (13%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAI-----LELLKYHP-RVLYIDIDVHH 786
HHA+ E GFC+ N + +A L+ P RV+ +D DVHH
Sbjct: 611 HHAEPGEACGFCFFNTVALAARYAQRLQSQSEDPLRVMILDWDVHH 656
>UniRef50_Q4PCR1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 727
Score = 40.3 bits (90), Expect = 0.054
Identities = 40/184 (21%), Positives = 73/184 (39%), Gaps = 8/184 (4%)
Frame = +1
Query: 259 STMTQQRVAYFYNPDVGNFHYGP---GHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRAS 429
S++ + R Y Y+ D+ H P HP +P R+ + L +M+ +
Sbjct: 77 SSLDRYRTGYVYSADM-MLHVNPIDPDHPERPLRIFKIFMKFKESNLFARMKRVPIREVA 135
Query: 430 AHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLE- 606
++ H E +Q + + + + + E + G ++E
Sbjct: 136 EEEVKLVHDHGIWEGVQRLAFYHPDVLKEQVQLLETNSSLYINEHSAYAARLSCGGAIEL 195
Query: 607 -GAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH---PRVLYIDI 774
A+ AI G HHA+ + GFC+ N++ +A +L+ H +VL +D
Sbjct: 196 VNAVAAGQIQNGFAIVRPPG-HHAEPQKSMGFCFFNNVAVATRVVLRRHAHIKKVLILDW 254
Query: 775 DVHH 786
DVHH
Sbjct: 255 DVHH 258
>UniRef50_Q4P2D6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1188
Score = 40.3 bits (90), Expect = 0.054
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH P GFC+VN+ ++A H RV+ DID+HH
Sbjct: 480 HHCSGSTPQGFCWVNNAIVAAAHAYHEHSIDRVVIFDIDLHH 521
>UniRef50_A2BL29 Cluster: Predicted Histone deacetylase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Predicted Histone
deacetylase - Hyperthermus butylicus (strain DSM 5456 /
JCM 9403)
Length = 357
Score = 40.3 bits (90), Expect = 0.054
Identities = 49/181 (27%), Positives = 72/181 (39%), Gaps = 11/181 (6%)
Frame = +1
Query: 277 RVAYFYNPDVGNFHYGP--GHPMKPHRLAVTHCLVLKYGLHKKMQIYK-PYRASAHD-MC 444
RV +Y+ +V H P HP P RLA+ + K GL+ + I P R D +
Sbjct: 3 RVCMYYD-EVFRLHEPPYGSHPESPERLAIALESLAKTGLYTLVHIQPAPRRGLERDRIL 61
Query: 445 RFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLN 624
H Y+E ++ + + Y + D V + YT + L+ KL
Sbjct: 62 EVHDPAYVEKVEELAGRG-GGY--------IDPDTYVGKYTILAAHAYTASVLDAVDKLV 112
Query: 625 NNTCDIAINWSGGL-HHAKKF-----EPS-GFCYVNDIVIAILELLKYHPRVLYIDIDVH 783
C+IAI HHA + P+ GFC N +A VL +D D+H
Sbjct: 113 EGDCNIAIVLGRPPGHHAGRRGVAMGAPTLGFCIFNISALAAKHAANRGENVLVVDFDLH 172
Query: 784 H 786
H
Sbjct: 173 H 173
>UniRef50_Q6AJC0 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 324
Score = 39.9 bits (89), Expect = 0.071
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELL-KY-HPRVLYIDIDVHH 786
HHA+K +P GFC+ N+++IA KY RV ID D HH
Sbjct: 130 HHAEKGKPFGFCFYNNVLIAARYWQEKYGRRRVAVIDFDAHH 171
>UniRef50_A1ID65 Cluster: Histone deacetylase family protein; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Histone
deacetylase family protein - Candidatus Desulfococcus
oleovorans Hxd3
Length = 345
Score = 39.9 bits (89), Expect = 0.071
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 3/158 (1%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNI 501
G HP P RLA + +V ++ + P A+ + H+ +++ + I
Sbjct: 19 GHAHPESPSRLASIYRMVDRH-FAGTVTTMTPEPATLDQLELVHTPGHVKKILKTAEHKI 77
Query: 502 QSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGL-HHAK 678
S + D PV + + GA ++G L + C + HHA
Sbjct: 78 TS---------MAPDTPVSGHSYLAAWLAAGACMQGVDLLLSGACRAFFSLVRPPGHHAL 128
Query: 679 KFEPSGFCYVNDIVIAI-LELLKYH-PRVLYIDIDVHH 786
+GFC +N++ IA ++Y+ R+L +D DVHH
Sbjct: 129 PDRATGFCLLNNLAIAARYARMRYNLERILIVDWDVHH 166
>UniRef50_A0LGT0 Cluster: Histone deacetylase superfamily; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Histone
deacetylase superfamily - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 316
Score = 39.9 bits (89), Expect = 0.071
Identities = 40/160 (25%), Positives = 60/160 (37%), Gaps = 5/160 (3%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNI 501
G HP P RL + V + GL ++ + K A + HS +I + +
Sbjct: 18 GSNHPESPERLEAVYRGVEEAGLFPRLTLIKASPAKLKWIEAVHSPKHIMRFEEACLLEM 77
Query: 502 QSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCD---IAINWSGGLHH 672
+ D + ++ + G LE + D A+ G HH
Sbjct: 78 GEFDHP--------DNQMCRESYETALLAVGGLLEAVRMVMEGIIDNAFCAVRPPG--HH 127
Query: 673 AKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
A+ GFCY N++ IA LL RV +DID HH
Sbjct: 128 AEMNRALGFCYFNNVAIAARYLLNEWGVERVGIVDIDAHH 167
>UniRef50_Q969S8 Cluster: Histone deacetylase 10; n=20;
Euteleostomi|Rep: Histone deacetylase 10 - Homo sapiens
(Human)
Length = 669
Score = 39.9 bits (89), Expect = 0.071
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 6/155 (3%)
Frame = +1
Query: 340 KPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKD 519
+P RL + + GL ++ AS ++ HS +Y+ ++ Q K+
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRET-----QVLGKE 81
Query: 520 LLHYNVGD-DCPVFE-GLFDFCSMYTGASLE--GAMKLNNNTCDIAINWSGGLHHAKKFE 687
L G D F F + GA L+ A+ +A+ G HH ++
Sbjct: 82 ELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAA 140
Query: 688 PSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+GFC N++ IA + H R+L +D DVHH
Sbjct: 141 ANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHH 175
>UniRef50_Q2SC27 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Hahella chejuensis KCTC 2396|Rep: Deacetylases,
including yeast histone deacetylase and acetoin
utilization protein - Hahella chejuensis (strain KCTC
2396)
Length = 318
Score = 39.5 bits (88), Expect = 0.094
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHPR------VLYIDIDVH 783
I N GG HHA + GFC+ +D +AI +LL+ R VL ID+D H
Sbjct: 123 IVFNLGGGFHHAFRDHGEGFCFFSDAALAI-QLLRAEKRLGSADEVLMIDLDAH 175
>UniRef50_Q10IB7 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 73
Score = 39.5 bits (88), Expect = 0.094
Identities = 16/31 (51%), Positives = 20/31 (64%)
Frame = +1
Query: 610 AMKLNNNTCDIAINWSGGLHHAKKFEPSGFC 702
A L + DIAINWSG +HHA + +GFC
Sbjct: 43 ACVLVDGASDIAINWSGNMHHASACKANGFC 73
>UniRef50_Q7Z8L6 Cluster: Putative histone deacetylase; n=2;
Pleosporales|Rep: Putative histone deacetylase -
Cochliobolus carbonum (Bipolaris zeicola)
Length = 847
Score = 39.5 bits (88), Expect = 0.094
Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP----RVLYIDIDVHH 786
HHA+ +PSGFC N++ IA +P +VL +D DVHH
Sbjct: 261 HHAESDQPSGFCIFNNVPIATRVCQNAYPETCRKVLILDWDVHH 304
>UniRef50_Q9HSP7 Cluster: Acetoin utilization protein; n=5;
Halobacteriaceae|Rep: Acetoin utilization protein -
Halobacterium salinarium (Halobacterium halobium)
Length = 338
Score = 39.5 bits (88), Expect = 0.094
Identities = 42/159 (26%), Positives = 61/159 (38%), Gaps = 4/159 (2%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQI-YKPYR-ASAHDMCRFHSEDYIEFLQNVTPQ 495
G HP P RL +K GL K+ + Y+ A D+ H DY +++ +
Sbjct: 15 GVRHPESPDRLRA-----IKRGLQKRHGVTYEDAPDADLSDITAVHDPDYATEVRSFCER 69
Query: 496 NIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHA 675
S+ D P A+L+GA + ++ G HHA
Sbjct: 70 GGGSWDPDTAATE--STWPAIRASAGLAMDAIDAALDGA---DGRDTPFSLGRPPG-HHA 123
Query: 676 KKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
+ GFC+VN+ +A L H RV D DVHH
Sbjct: 124 ITDDAMGFCFVNNAAVAAQHALDAHGLDRVAIFDWDVHH 162
>UniRef50_Q4T0M8 Cluster: Chromosome undetermined SCAF10929, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10929, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 903
Score = 39.1 bits (87), Expect = 0.12
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVHH 786
HHA P GFCY N + IA +L ++L +D DVHH
Sbjct: 553 HHADPSNPMGFCYFNSVAIAAKQLQHKLSVSKILIVDWDVHH 594
>UniRef50_Q7U7V3 Cluster: Putative histone deacetylase/AcuC/AphA
family protein; n=4; Synechococcus|Rep: Putative histone
deacetylase/AcuC/AphA family protein - Synechococcus sp.
(strain WH8102)
Length = 323
Score = 39.1 bits (87), Expect = 0.12
Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
IA + +GG HHA SGFC ND+ LL R+L +D+DVH
Sbjct: 129 IACHLAGGTHHAHPGFGSGFCIFNDVATTARVLLDNGEVQRLLVVDLDVH 178
>UniRef50_Q1VK67 Cluster: Histone deacetylase family protein; n=1;
Psychroflexus torquis ATCC 700755|Rep: Histone
deacetylase family protein - Psychroflexus torquis ATCC
700755
Length = 344
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKY--HPRVLYIDIDVH 783
+A N +GG HHA + SG+C ND+ + L + RV +D+DVH
Sbjct: 135 LAGNMAGGTHHAHREFGSGYCVFNDLAVCALHAITSLGVGRVAVLDLDVH 184
>UniRef50_A1I9M7 Cluster: Histone deacetylase superfamily; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Histone
deacetylase superfamily - Candidatus Desulfococcus
oleovorans Hxd3
Length = 578
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/40 (47%), Positives = 21/40 (52%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA+ GFCY N IA L H RV +DID HH
Sbjct: 393 HHAETSMFGGFCYFNSAAIA-AHYLSRHGRVAILDIDYHH 431
>UniRef50_Q5VP96 Cluster: HGWP repeat containing protein-like; n=1;
Oryza sativa (japonica cultivar-group)|Rep: HGWP repeat
containing protein-like - Oryza sativa subsp. japonica
(Rice)
Length = 145
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/72 (26%), Positives = 33/72 (45%)
Frame = +1
Query: 436 DMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAM 615
D+ S+DY+ L V P+ + L +NV +DCP+F G + +C G +
Sbjct: 67 DLRLLRSDDYVASLPAVLPE---LWICSLCRFNVDEDCPIFHGFYIYCQTCAGDCARAII 123
Query: 616 KLNNNTCDIAIN 651
+ ++ IN
Sbjct: 124 DRYHGAQNVVIN 135
>UniRef50_Q4QI60 Cluster: Histone deacetylase, putative; n=3;
Leishmania|Rep: Histone deacetylase, putative -
Leishmania major
Length = 533
Score = 39.1 bits (87), Expect = 0.12
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 8/47 (17%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--------PRVLYIDIDVH 783
HH +PSGFC VN++ IA +L H PR+ +D+DVH
Sbjct: 219 HHCTASQPSGFCLVNNVAIAAQQLRIRHASALASGPPRIAILDLDVH 265
>UniRef50_Q7S8C9 Cluster: Putative uncharacterized protein
NCU07018.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU07018.1 - Neurospora crassa
Length = 1212
Score = 39.1 bits (87), Expect = 0.12
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC+VN++ + I+ + H ID D+HH
Sbjct: 419 HHCSASYPSGFCWVNNVHVGIMHAILSHGLTHAAIIDFDLHH 460
>UniRef50_UPI0000F2108C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 673
Score = 38.7 bits (86), Expect = 0.16
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVHH 786
HHA P GFC+ N + IA +L + ++L +D DVHH
Sbjct: 391 HHADPSNPMGFCFFNSVAIAAKQLQQKLSASKILIVDWDVHH 432
>UniRef50_UPI0000E463DB Cluster: PREDICTED: similar to histone
deacetylase-4; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to histone deacetylase-4 -
Strongylocentrotus purpuratus
Length = 1012
Score = 38.7 bits (86), Expect = 0.16
Identities = 20/42 (47%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILEL-LKYH-PRVLYIDIDVHH 786
HHA+ + GFC+ N I IA +L LK ++L ID DVHH
Sbjct: 772 HHAETSQAMGFCFFNSIAIAAKQLRLKLKLNKILIIDWDVHH 813
>UniRef50_UPI000023CBFE Cluster: hypothetical protein FG05636.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05636.1 - Gibberella zeae PH-1
Length = 1144
Score = 38.7 bits (86), Expect = 0.16
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC+VN++ + I+ H ID D+HH
Sbjct: 341 HHCSASHPSGFCWVNNVHVGIMHAALEHGLTHAAIIDFDLHH 382
>UniRef50_Q5LRW9 Cluster: Acetylpolyamine aminohydrolase; n=7;
Rhodobacteraceae|Rep: Acetylpolyamine aminohydrolase -
Silicibacter pomeroyi
Length = 341
Score = 38.7 bits (86), Expect = 0.16
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Frame = +1
Query: 547 CPVFEGLFDFCSMYTGASLEGA-MKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVI 723
CP+ EG ++ +++ GA + + ++ G HHA GFC++N+ I
Sbjct: 117 CPIAEGTWEAAYWSAQSAITGADLIIQGERSAYVLSRPPG-HHAFGDLAGGFCFLNNSAI 175
Query: 724 AILELLKYHPRVLYIDIDVHH 786
A L R +DIDVHH
Sbjct: 176 AAERLRAAGLRPAILDIDVHH 196
>UniRef50_Q0W553 Cluster: Putative acetoin utilization protein; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
acetoin utilization protein - Uncultured methanogenic
archaeon RC-I
Length = 331
Score = 38.7 bits (86), Expect = 0.16
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 1/123 (0%)
Frame = +1
Query: 421 RASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGAS 600
RA+ + R H DY+ ++I++ +L D + G D + GA+
Sbjct: 50 RAAERQLTRVHDLDYV--------RHIETSGTGMLD----PDTEMTAGSLDAARLAAGAA 97
Query: 601 LEGAMKLNNNTCDIAINWSGGL-HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDID 777
L+ ++ ++A HHA GFC N+ I L ++ +VL +D D
Sbjct: 98 LDAVEEVRKGR-ELAFGLVRPPGHHALPGRAMGFCIFNNAAIGAARALDHYRKVLVVDWD 156
Query: 778 VHH 786
VHH
Sbjct: 157 VHH 159
>UniRef50_Q20296 Cluster: Histone deacetylase 6; n=4;
Caenorhabditis|Rep: Histone deacetylase 6 -
Caenorhabditis elegans
Length = 955
Score = 38.7 bits (86), Expect = 0.16
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILE-LLKYHPRVLYIDIDVHH 786
HHA P GFC N++ A E R+L +D+DVHH
Sbjct: 145 HHADSVSPCGFCLFNNVAQAAEEAFFSGAERILIVDLDVHH 185
Score = 38.7 bits (86), Expect = 0.16
Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA + SGFC N++ +A + H RVL +D DVHH
Sbjct: 560 HHASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHH 601
>UniRef50_Q8LRK8 Cluster: Histone deacetylase 18; n=1; Arabidopsis
thaliana|Rep: Histone deacetylase 18 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 682
Score = 38.7 bits (86), Expect = 0.16
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Frame = +1
Query: 634 CDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYHP-----RVLYIDIDVHH 786
C AI G HHA+ E GFC N++ +A LL P ++L +D D+HH
Sbjct: 180 CGFAIVRPPG-HHAESDEAMGFCLFNNVAVAASFLLNERPDLDVKKILIVDWDIHH 234
>UniRef50_Q604Q2 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=29; Proteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Methylococcus
capsulatus
Length = 310
Score = 38.3 bits (85), Expect = 0.22
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA+ GFC N+I IA L H R+ +D DVHH
Sbjct: 124 HHAEPDAAMGFCLFNNIAIAAAHALANHGLQRIAIVDFDVHH 165
>UniRef50_A5UTM3 Cluster: Histone deacetylase superfamily; n=4;
Bacteria|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 298
Score = 38.3 bits (85), Expect = 0.22
Identities = 42/150 (28%), Positives = 66/150 (44%), Gaps = 4/150 (2%)
Frame = +1
Query: 346 HRLAVTHCLVLKYGLHKKM--QIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKD 519
HR +T +L+ + ++ P A D+ R H+ DY+ +Q I + S D
Sbjct: 17 HRFPITKYAMLRERASAEGLGELIVPAAADDRDILRAHTADYLHRIQ------IGAMS-D 69
Query: 520 LLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGF 699
+G P L + GA++ A + + IA + +GG HHA G+
Sbjct: 70 REMRQIG--FPWSPHLVERSRRSVGATI-AACRTALSGDGIAASLAGGTHHAFADHGEGY 126
Query: 700 CYVNDIVIA--ILELLKYHPRVLYIDIDVH 783
C ND VIA +++ RV+ ID DVH
Sbjct: 127 CVFNDSVIAARVMQAEGRVRRVVIIDCDVH 156
>UniRef50_A5GUP9 Cluster: Histone deacetylase family protein; n=14;
cellular organisms|Rep: Histone deacetylase family
protein - Synechococcus sp. (strain RCC307)
Length = 306
Score = 38.3 bits (85), Expect = 0.22
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +1
Query: 640 IAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
+A + +GG HHA SGFC NDI + LL+ +++ +D+DVH
Sbjct: 113 MACHLAGGTHHAFPDYGSGFCIFNDIAVTASVLLQQGLVNKLMVVDLDVH 162
>UniRef50_Q2H2N4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 1145
Score = 38.3 bits (85), Expect = 0.22
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC+VN++ + I+ + H ID D+HH
Sbjct: 350 HHCSASHPSGFCWVNNVHVGIMHGVLSHGLTHAAIIDFDLHH 391
>UniRef50_Q0G2C9 Cluster: Putative acetylpolyamine aminohydrolase;
n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
acetylpolyamine aminohydrolase - Fulvimarina pelagi
HTCC2506
Length = 347
Score = 37.9 bits (84), Expect = 0.29
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA +GFC+ N+ IA L + +V ID D HH
Sbjct: 165 HHAYPDRANGFCFFNNAAIAAQRLRSKYGKVAIIDFDTHH 204
>UniRef50_Q8IJW3 Cluster: Putative uncharacterized protein; n=3;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 2379
Score = 37.9 bits (84), Expect = 0.29
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELL-KYHPRVLYI-DIDVHH 786
HH + PSGFC N+I +A + KY R ++I D DVHH
Sbjct: 970 HHCSRSHPSGFCIFNNISVACKYIFKKYGIRKVFIFDWDVHH 1011
>UniRef50_A5K7A1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 2206
Score = 37.9 bits (84), Expect = 0.29
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELL-KYHPRVLYI-DIDVHH 786
HH + PSGFC N+I +A + KY R ++I D DVHH
Sbjct: 893 HHCSRNSPSGFCIFNNISVACKYIFKKYGIRKIFIFDWDVHH 934
>UniRef50_UPI000065F55A Cluster: Histone deacetylase 7a (HD7a).;
n=1; Takifugu rubripes|Rep: Histone deacetylase 7a
(HD7a). - Takifugu rubripes
Length = 752
Score = 37.5 bits (83), Expect = 0.38
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVHH 786
HHA P GFC+ N + IA +L + ++L +D D+HH
Sbjct: 442 HHATHSSPLGFCFFNSVAIAAKQLQQRLNVSKILIVDWDIHH 483
>UniRef50_Q63YT0 Cluster: Histone deacetylase family protein; n=12;
Burkholderia|Rep: Histone deacetylase family protein -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 370
Score = 37.5 bits (83), Expect = 0.38
Identities = 39/151 (25%), Positives = 59/151 (39%), Gaps = 5/151 (3%)
Frame = +1
Query: 349 RLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQSYSKDLLH 528
RLA T L+ G+ +++ RA+ + R H +Y+ L + +
Sbjct: 40 RLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLAEACAVAGEQVVR---- 95
Query: 529 YNVGDDCPVFEGLFDFCSMYTGAS---LEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGF 699
+GDD D + GA+ ++ M I SG HHA G+
Sbjct: 96 --LGDDAAGSASTEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSG--HHAGADFAMGY 151
Query: 700 CYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
CY N++ IA H RV +D DVHH
Sbjct: 152 CYYNNVAIAARHAQAAHGVERVAIVDWDVHH 182
>UniRef50_A6VSZ5 Cluster: Histone deacetylase superfamily; n=4;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Marinomonas sp. MWYL1
Length = 307
Score = 37.5 bits (83), Expect = 0.38
Identities = 39/172 (22%), Positives = 70/172 (40%), Gaps = 4/172 (2%)
Frame = +1
Query: 283 AYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSED 462
AY + G HP P RL ++ L ++ + A+ + H E
Sbjct: 4 AYITHTYCDKHDMGEDHPESPLRLGAIQNRLIMGQLMDFLRRLESDPATREQLLLAHDEA 63
Query: 463 YIEFLQNVTPQ--NIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC 636
Y++ + P+ +++ + L+ + D L+ S+ L +++N C
Sbjct: 64 YVDSIFARAPEEGHVELEPETLMMPHTLD-----AALYAAGSVIKAVDLVMTSEMDNAFC 118
Query: 637 DIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
AI G HHA+ + GFC N+I + ++ + RV +D DVHH
Sbjct: 119 --AIRPPG--HHAEYDKAMGFCLFNNIAVGTRYAIEKYGLERVAIVDFDVHH 166
>UniRef50_A5UY48 Cluster: Histone deacetylase superfamily; n=4;
Chloroflexaceae|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 344
Score = 37.5 bits (83), Expect = 0.38
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKY--HPRVLYIDIDVHH 786
HHA + E GFC N++ IA + + RV +D DVHH
Sbjct: 123 HHATRAESMGFCLFNNVAIAARHAIDHLGVTRVAIVDFDVHH 164
>UniRef50_A0LFA3 Cluster: Histone deacetylase superfamily; n=3;
Deltaproteobacteria|Rep: Histone deacetylase superfamily
- Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 248
Score = 37.5 bits (83), Expect = 0.38
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 2/78 (2%)
Frame = +1
Query: 559 EGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILEL 738
+GL++ + G +++ A+ C I G HHA GFCY N++ +A+ L
Sbjct: 63 QGLYNIACLAAGGAIQTALTGLKEPCFGLIRPPG--HHASADSYWGFCYFNNMAVALDHL 120
Query: 739 LKY-HPRVLYI-DIDVHH 786
+ H + Y+ D D+H+
Sbjct: 121 KRNGHIKTAYVLDFDMHY 138
>UniRef50_A0IVC2 Cluster: Histone deacetylase superfamily; n=5;
Proteobacteria|Rep: Histone deacetylase superfamily -
Serratia proteamaculans 568
Length = 370
Score = 37.5 bits (83), Expect = 0.38
Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +1
Query: 322 GPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNI 501
G GH P L+ GL ++ + A+ D+ R H +Y++ + ++
Sbjct: 36 GAGHAESPETKRRMKNLMDVSGLSHQLSLLSAELATDEDLLRIHPANYLQRFKQLSDNGG 95
Query: 502 QSYSKDLLHYNVGDDCPVFEGLFDFCSMYTG---ASLEGAMKLNNNTCDIAINWSGGLHH 672
+G++ P+ G ++ + G A++E ++ A++ G HH
Sbjct: 96 GM---------LGEEAPLGPGSYEIAKLSAGLACAAVEAVLQGELENA-YALSRPPG-HH 144
Query: 673 AKKFEPSGFCYVNDIVIAILEL-LKYH-PRVLYIDIDVHH 786
+ GFC++ +I IAI KY +V +D DVHH
Sbjct: 145 CLPDQSMGFCFLANIPIAIERAKAKYGLGKVAVLDWDVHH 184
>UniRef50_Q7R8P2 Cluster: Histone deacetylase family, putative; n=1;
Plasmodium yoelii yoelii|Rep: Histone deacetylase
family, putative - Plasmodium yoelii yoelii
Length = 2009
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILEL-LKYHPRVLYI-DIDVHH 786
HH + PSGFC N+I +A + +KY + ++I D DVHH
Sbjct: 675 HHCSRNNPSGFCIFNNISVACKYIYIKYGIKKIFIFDWDVHH 716
>UniRef50_Q4YUE6 Cluster: Putative uncharacterized protein; n=3;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium berghei
Length = 1657
Score = 37.5 bits (83), Expect = 0.38
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILEL-LKYHPRVLYI-DIDVHH 786
HH + PSGFC N+I +A + +KY + ++I D DVHH
Sbjct: 416 HHCSRNNPSGFCIFNNISVACKYIYIKYGIKKIFIFDWDVHH 457
>UniRef50_A0DIS2 Cluster: Chromosome undetermined scaffold_52, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_52,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 645
Score = 37.5 bits (83), Expect = 0.38
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Frame = +1
Query: 451 HSEDYIEFLQNV-TPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKL-- 621
H E YI+F++ + + +KD+ ++ DD + + A LEG K+
Sbjct: 80 HDEKYIDFVEGLFNAVGNEQLTKDVKYF---DDTYLCKTSAVTARKCVQAVLEGVDKILK 136
Query: 622 ---NNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAI-LELLKYH-PRVLYIDIDVHH 786
N C + G H K +P+GFC N++ +A KY+ +++ D DVHH
Sbjct: 137 AEWRNGFCSVR---PPGHHSGHKNKPNGFCVYNNVAVAAKYARAKYNVNKIVIFDWDVHH 193
>UniRef50_A4QWC2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1124
Score = 37.5 bits (83), Expect = 0.38
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC+VN++ + I+ + H ID D+HH
Sbjct: 341 HHCSASFPSGFCWVNNVHVGIMHGILSHGLTHAAIIDFDLHH 382
>UniRef50_O17323 Cluster: Histone deacetylase 4; n=3;
Caenorhabditis|Rep: Histone deacetylase 4 -
Caenorhabditis elegans
Length = 816
Score = 37.5 bits (83), Expect = 0.38
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP----RVLYIDIDVHH 786
HHA+ + GFC+ N++ +A+ L +P ++ ID DVHH
Sbjct: 554 HHAEHEQAMGFCFFNNVAVAVKVLQTKYPAQCAKIAIIDWDVHH 597
>UniRef50_Q586J9 Cluster: Histone deacetylase, putative; n=1;
Trypanosoma brucei|Rep: Histone deacetylase, putative -
Trypanosoma brucei
Length = 685
Score = 31.1 bits (67), Expect(2) = 0.48
Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 2/137 (1%)
Frame = +1
Query: 325 PGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFLQNVTPQNIQ 504
PG +P RL T + GL + + A ++ HS ++I+ + + +
Sbjct: 137 PGDYERPGRLQRTLDHLEVIGLLECCRRLHHRSARTRELRLVHSTEHIDSVDQLEVATL- 195
Query: 505 SYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEGAMKLNNNTC--DIAINWSGGLHHAK 678
K NVG+D E G ++ A+ + A+ G HHA
Sbjct: 196 -LRKPGESCNVGEDLYANENTSRAARAAAGCAIAAALSVVRGEVRNSFALIRPPG-HHAG 253
Query: 679 KFEPSGFCYVNDIVIAI 729
+ SGFC+ N++ +A+
Sbjct: 254 RDRASGFCFFNNVAVAV 270
Score = 25.0 bits (52), Expect(2) = 0.48
Identities = 10/12 (83%), Positives = 10/12 (83%)
Frame = +1
Query: 751 PRVLYIDIDVHH 786
PRVL ID DVHH
Sbjct: 306 PRVLVIDWDVHH 317
>UniRef50_Q9U266 Cluster: Putative uncharacterized protein hda-6;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein hda-6 - Caenorhabditis elegans
Length = 517
Score = 37.1 bits (82), Expect = 0.50
Identities = 16/39 (41%), Positives = 22/39 (56%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVH 783
HHA E GFC N++ IA ++ +VL +D DVH
Sbjct: 137 HHAMPDEGCGFCIFNNVAIAAKAAIQNGQKVLIVDYDVH 175
>UniRef50_A0C8R8 Cluster: Chromosome undetermined scaffold_159,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_159,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 366
Score = 37.1 bits (82), Expect = 0.50
Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Frame = +1
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAI--LELLKYHPRVLYIDIDVH 783
AIN SGG HHA GFC DI + + L+ +++ +D+D H
Sbjct: 181 AINLSGGYHHASLNRGGGFCIYPDITLVVNYLKRCCNLKKIVIVDLDAH 229
>UniRef50_Q96DB2 Cluster: Histone deacetylase 11; n=22;
Eumetazoa|Rep: Histone deacetylase 11 - Homo sapiens
(Human)
Length = 347
Score = 37.1 bits (82), Expect = 0.50
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +1
Query: 643 AINWSGGLHHAKKFEPSGFCYVNDIVIAI---LELLKYHPRVLYIDIDVH 783
AIN GG HH GFC DI +AI E ++ R ID+D H
Sbjct: 134 AINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAH 183
>UniRef50_UPI000069F4DB Cluster: Histone deacetylase 7a (HD7a).;
n=3; Xenopus tropicalis|Rep: Histone deacetylase 7a
(HD7a). - Xenopus tropicalis
Length = 893
Score = 36.7 bits (81), Expect = 0.66
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAI--LELLKYHPRVLYIDIDVHH 786
HHA GFC+ N + IA L+L + ++L +D DVHH
Sbjct: 605 HHADPSTAMGFCFFNSVAIAAKQLQLRRDVRKILIVDWDVHH 646
>UniRef50_Q6KAT4 Cluster: MFLJ00062 protein; n=6; Eutheria|Rep:
MFLJ00062 protein - Mus musculus (Mouse)
Length = 852
Score = 36.7 bits (81), Expect = 0.66
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKY--HPRVLYIDIDVHH 786
HHA GFC+ N + IA +L ++ ++L +D DVHH
Sbjct: 570 HHADHSTAMGFCFFNSVAIACRQLQQHGKASKILIVDWDVHH 611
>UniRef50_Q1PVG5 Cluster: Similar to histone deacetylase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
histone deacetylase - Candidatus Kuenenia
stuttgartiensis
Length = 313
Score = 36.7 bits (81), Expect = 0.66
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA GFC N++ IA L K + R+L ID DVHH
Sbjct: 123 HHATPDRGMGFCLFNNVAIAARYLQKNYQQKRILIIDWDVHH 164
>UniRef50_A4AX75 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=4; Alteromonadales|Rep: Histone
deacetylase/AcuC/AphA family protein - Alteromonas
macleodii 'Deep ecotype'
Length = 326
Score = 36.7 bits (81), Expect = 0.66
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA GFC N+IVIA L+ + RV +D DVHH
Sbjct: 140 HHATYDSAMGFCVFNNIVIAARYALQNYGLKRVAIVDFDVHH 181
>UniRef50_Q8I9J6 Cluster: Histone deacetylase dHDAC4 isoform b; n=7;
Sophophora|Rep: Histone deacetylase dHDAC4 isoform b -
Drosophila melanogaster (Fruit fly)
Length = 1255
Score = 36.7 bits (81), Expect = 0.66
Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 3/43 (6%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP---RVLYIDIDVHH 786
HHA+ GFC+ N I IA L + P R+L +D DVHH
Sbjct: 970 HHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHH 1012
>UniRef50_A6GQW9 Cluster: Histone deacetylase family protein; n=1;
Limnobacter sp. MED105|Rep: Histone deacetylase family
protein - Limnobacter sp. MED105
Length = 306
Score = 36.3 bits (80), Expect = 0.88
Identities = 43/175 (24%), Positives = 67/175 (38%), Gaps = 7/175 (4%)
Frame = +1
Query: 283 AYFYNPDVGNFHYGPGHPMKPHRLAVTHCLVLKYGLHKKMQIYKPYRASAHDMCRFHSED 462
AY + D + G GHP RL V + L ++ + + + H+
Sbjct: 4 AYISHSDCALHNPGLGHPESMARLRVIREKLESSELWPRLVHCEAPEVAWSAVTAVHNPA 63
Query: 463 YIEFLQNVTPQNIQSYSKDLLHYNVGDDCPVFEGLFDFCSMYTGASLEG-----AMKLNN 627
Y+E ++ P + ++ D + E D GA + A +NN
Sbjct: 64 YVESIKARFPLK--------RNIDIDGDTTLSEFSLDAARRAAGACVHAVDLVMAHAVNN 115
Query: 628 NTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
C A+ G HHA GFC N++ IA + + RVL +D DVHH
Sbjct: 116 AFC--AVRPPG--HHACVDRAMGFCVFNNVAIAAQHAIDAYRLERVLIVDFDVHH 166
>UniRef50_A3VQ74 Cluster: Probable histone deacetylase/AcuC/AphA
family protein; n=1; Parvularcula bermudensis
HTCC2503|Rep: Probable histone deacetylase/AcuC/AphA
family protein - Parvularcula bermudensis HTCC2503
Length = 299
Score = 36.3 bits (80), Expect = 0.88
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Frame = +1
Query: 655 SGGLHHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVH 783
+GG HHA SG+C ND + LL R+ +D+DVH
Sbjct: 114 AGGTHHAHAEAGSGYCIYNDFAVVARTLLNEGVVDRIAIVDLDVH 158
>UniRef50_Q2QWU2 Cluster: Histone deacetylase family protein,
expressed; n=4; Magnoliophyta|Rep: Histone deacetylase
family protein, expressed - Oryza sativa subsp. japonica
(Rice)
Length = 443
Score = 36.3 bits (80), Expect = 0.88
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA P GFC +I +A H RV+ ID DVHH
Sbjct: 221 HHAVPEGPMGFCVFGNIAVAARYAQNQHGLKRVMIIDFDVHH 262
>UniRef50_A7SSG8 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 369
Score = 36.3 bits (80), Expect = 0.88
Identities = 34/145 (23%), Positives = 67/145 (46%), Gaps = 9/145 (6%)
Frame = +1
Query: 379 KYGLHKKMQIYKPYRASAHDMCRFHSEDYIEFL---QNVTPQNIQSYSKDLLHYNVGDDC 549
+YGL + A+ D+ HS+++I+ + Q++ P+++ + ++ + D
Sbjct: 45 EYGLLDRCYKIPSRHATEEDLLCLHSKEHIDKMKSTQDMKPRDLFNLGEEYDSIYMSKD- 103
Query: 550 PVFEGLFDFCSMYTGASLEGAMKLNNNTCDIAINWSGGL----HHAKKFEPSGFCYVNDI 717
V++ C T A++E ++ I IN L HHA G+C+ N++
Sbjct: 104 -VYDCALLSCGC-TLAAVEHVATNKSSKHSIHINQLFFLRPPGHHADADSAMGYCFFNNV 161
Query: 718 VIA--ILELLKYHPRVLYIDIDVHH 786
IA + + R+L +D D+HH
Sbjct: 162 AIAAKLAQQRWGMQRILIVDWDIHH 186
>UniRef50_Q941D6 Cluster: Histone deacetylase 14; n=3;
Spermatophyta|Rep: Histone deacetylase 14 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 423
Score = 36.3 bits (80), Expect = 0.88
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA P GFC ++ IA + H R+ ID DVHH
Sbjct: 201 HHAVPKGPMGFCVFGNVAIAARHAQRTHGLKRIFIIDFDVHH 242
>UniRef50_Q985Y7 Cluster: Mlr7469 protein; n=13;
Alphaproteobacteria|Rep: Mlr7469 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 308
Score = 35.9 bits (79), Expect = 1.2
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA+K GFC+ N IA H RV +D DVHH
Sbjct: 124 HHAEKTTAMGFCFFNTAAIAARYAQNKHGAERVAVVDWDVHH 165
>UniRef50_Q30PJ4 Cluster: Histone deacetylase superfamily; n=1;
Thiomicrospira denitrificans ATCC 33889|Rep: Histone
deacetylase superfamily - Thiomicrospira denitrificans
(strain ATCC 33889 / DSM 1351)
Length = 577
Score = 35.9 bits (79), Expect = 1.2
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA++ GFCY N +A L + +V +D+D HH
Sbjct: 392 HHAERRTLGGFCYFNSAAVAAHHLSSF-GKVAVLDVDFHH 430
>UniRef50_A3ZYN7 Cluster: Acetoin utilization protein; n=3;
Planctomycetaceae|Rep: Acetoin utilization protein -
Blastopirellula marina DSM 3645
Length = 311
Score = 35.9 bits (79), Expect = 1.2
Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKY--HPRVLYIDIDVHH 786
HHA P GFC N + IA L RVL +D DVHH
Sbjct: 122 HHATPTMPMGFCLFNSVAIAAQYALSKLDLDRVLIVDWDVHH 163
>UniRef50_A1G0Y5 Cluster: Histone deacetylase superfamily precursor;
n=1; Stenotrophomonas maltophilia R551-3|Rep: Histone
deacetylase superfamily precursor - Stenotrophomonas
maltophilia R551-3
Length = 312
Score = 35.9 bits (79), Expect = 1.2
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA GFC +N+I IA H R+ +D DVHH
Sbjct: 121 HHATSSTAMGFCLLNNIAIAAAYARDRHGLERIAVVDFDVHH 162
>UniRef50_A0G5H0 Cluster: Histone deacetylase superfamily; n=9;
Proteobacteria|Rep: Histone deacetylase superfamily -
Burkholderia phymatum STM815
Length = 315
Score = 35.9 bits (79), Expect = 1.2
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA+ + GFC N IA + H RV +D DVHH
Sbjct: 126 HHAEPSKAMGFCIFNQAAIAAAYAYEVHKLERVAVVDFDVHH 167
>UniRef50_Q4CZ55 Cluster: Histone deacetylase, putative; n=2;
Trypanosoma cruzi|Rep: Histone deacetylase, putative -
Trypanosoma cruzi
Length = 661
Score = 35.9 bits (79), Expect = 1.2
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 7/47 (14%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAI----LELLKY---HPRVLYIDIDVHH 786
HHA E SGFC+ N++ +A+ EL + PR L D DVHH
Sbjct: 236 HHAGVNEASGFCFFNNVAVAVRVAQQELRQQGISAPRALVFDWDVHH 282
>UniRef50_Q6CGA7 Cluster: Similar to sp|Q02959 Saccharomyces
cerevisiae HOS3 protein; n=1; Yarrowia lipolytica|Rep:
Similar to sp|Q02959 Saccharomyces cerevisiae HOS3
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 715
Score = 35.9 bits (79), Expect = 1.2
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH +PSGFC +N+ +AI K + + +D D+HH
Sbjct: 412 HHCHACDPSGFCLINNAHVAIQYAAKQYGVTHAVILDFDLHH 453
>UniRef50_Q4W9N7 Cluster: Histone deacetylase HosB; n=3;
Trichocomaceae|Rep: Histone deacetylase HosB -
Aspergillus fumigatus (Sartorya fumigata)
Length = 1191
Score = 35.9 bits (79), Expect = 1.2
Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC++N++ + I H +D D+HH
Sbjct: 361 HHCSTSHPSGFCWINNVHVGITYAAMTHGLTHAAILDFDLHH 402
>UniRef50_Q8WUI4 Cluster: Histone deacetylase 7a; n=41;
Tetrapoda|Rep: Histone deacetylase 7a - Homo sapiens
(Human)
Length = 952
Score = 35.9 bits (79), Expect = 1.2
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA GFC+ N + IA +L + ++L +D DVHH
Sbjct: 669 HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHH 710
>UniRef50_UPI000051A1DA Cluster: PREDICTED: similar to HDAC4
CG1770-PB, isoform B; n=2; Apocrita|Rep: PREDICTED:
similar to HDAC4 CG1770-PB, isoform B - Apis mellifera
Length = 1048
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
HHA+ + GFC+ N I IA +L+ ++L +D DVHH
Sbjct: 759 HHAETNQAMGFCFFNSIAIAARLLQQKLDIRKILILDWDVHH 800
>UniRef50_Q9RW36 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=4; Deinococci|Rep: Histone
deacetylase/AcuC/AphA family protein - Deinococcus
radiodurans
Length = 301
Score = 35.5 bits (78), Expect = 1.5
Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Frame = +1
Query: 649 NWSGGLHHAKKFEPSGFCYVNDIVIAILELLK--YHPRVLYIDIDVH 783
N +GG HHA GFC VND I L RV +D+DVH
Sbjct: 111 NLAGGTHHAFHDRAEGFCLVNDAAILTRIALDRGLARRVATLDLDVH 157
>UniRef50_Q02CA3 Cluster: Histone deacetylase superfamily; n=1;
Solibacter usitatus Ellin6076|Rep: Histone deacetylase
superfamily - Solibacter usitatus (strain Ellin6076)
Length = 312
Score = 35.5 bits (78), Expect = 1.5
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA GFC +N++ IA + H RV +D DVHH
Sbjct: 125 HHANAARGMGFCLLNNVAIAARYAQRRHGIERVAIVDWDVHH 166
>UniRef50_A6LM84 Cluster: Histone deacetylase superfamily; n=1;
Thermosipho melanesiensis BI429|Rep: Histone deacetylase
superfamily - Thermosipho melanesiensis BI429
Length = 315
Score = 35.5 bits (78), Expect = 1.5
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLK-YHPRVLYIDIDVHH 786
HHA K G+C+ N+ I L Y R+ +DID HH
Sbjct: 131 HHASKDFAGGYCFFNNAAIIAKYLQSIYQKRICILDIDFHH 171
>UniRef50_Q5AF34 Cluster: Likely histone deacetylase Hos3p; n=5;
Saccharomycetales|Rep: Likely histone deacetylase Hos3p
- Candida albicans (Yeast)
Length = 713
Score = 35.5 bits (78), Expect = 1.5
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Frame = +1
Query: 616 KLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
K N+N + I G HH+ PSGFC +N++ I I + + +DID+HH
Sbjct: 300 KENHNLAFVVIRPPG--HHSHACLPSGFCLLNNVQIGIEYAFEQYGVTHCAILDIDLHH 356
>UniRef50_Q1DM14 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1084
Score = 35.5 bits (78), Expect = 1.5
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC++N++ + I H ID D+HH
Sbjct: 361 HHCSSNFPSGFCWLNNVHVGIAHAAMTHGLTHAAIIDFDLHH 402
>UniRef50_O28982 Cluster: Acetoin utilization protein, putative;
n=1; Archaeoglobus fulgidus|Rep: Acetoin utilization
protein, putative - Archaeoglobus fulgidus
Length = 189
Score = 35.5 bits (78), Expect = 1.5
Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Frame = +1
Query: 616 KLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELL-KY-HPRVLYIDIDVHH 786
+L N C I +GG HHA + G+C ND+V+AI L K+ RV ID D HH
Sbjct: 6 ELKNAFCYIG---AGG-HHAGRDYFWGYCCFNDVVLAIQNLYDKFGELRVAIIDTDAHH 60
>UniRef50_UPI0000D561E8 Cluster: PREDICTED: similar to CG1770-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG1770-PA, isoform A - Tribolium castaneum
Length = 883
Score = 35.1 bits (77), Expect = 2.0
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA+ + GFC+ N + IA L + H ++L D VHH
Sbjct: 606 HHAEPQQAMGFCFFNSVAIAARVLQREHRVHKILIFDWGVHH 647
>UniRef50_Q17I08 Cluster: Histone deacetylase; n=1; Aedes
aegypti|Rep: Histone deacetylase - Aedes aegypti
(Yellowfever mosquito)
Length = 1112
Score = 35.1 bits (77), Expect = 2.0
Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 5/45 (11%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH-----PRVLYIDIDVHH 786
HHA+ GFC+ N I IA +LL+ RVL +D DVHH
Sbjct: 820 HHAEPNAAMGFCFFNSIAIA-AKLLRQRLSSEIQRVLVVDWDVHH 863
>UniRef50_A5E451 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 793
Score = 35.1 bits (77), Expect = 2.0
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Frame = +1
Query: 616 KLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
K N+N + I G HH+ PSGFC +N++ I I + + +DID+HH
Sbjct: 352 KPNHNLAFVVIRPPG--HHSHACLPSGFCLLNNVQIGIEYAFETYGVTHCAILDIDLHH 408
>UniRef50_A2R2F5 Cluster: Remark: N-terminal truncated orf due to
end of contig. precursor; n=5; Trichocomaceae|Rep:
Remark: N-terminal truncated orf due to end of contig.
precursor - Aspergillus niger
Length = 1347
Score = 35.1 bits (77), Expect = 2.0
Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC++N++ + I H +D D+HH
Sbjct: 407 HHCSAGHPSGFCWINNVHVGISYAAMTHGLTHAAILDFDLHH 448
>UniRef50_A5UZV6 Cluster: Histone deacetylase superfamily; n=5;
Bacteria|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 346
Score = 34.7 bits (76), Expect = 2.7
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 4/90 (4%)
Frame = +1
Query: 529 YNVGDDC-PVFEGLFDFCSMYTGASLEGAMKL-NNNTCDIAINWSGGLHHAKKFEPSGFC 702
Y D C P+ G + +L GA +L C A+ G HHA + G+C
Sbjct: 111 YYTFDTCAPIVAGTYAAARAAADIALTGADRLLAGERCVYALCRPPG-HHAGRDLCGGYC 169
Query: 703 YVNDIVIAILELLK--YHPRVLYIDIDVHH 786
++N+ IA L++ +DIDVHH
Sbjct: 170 FLNNAAIAAEYLIRNAAGATCAILDIDVHH 199
>UniRef50_A6RSL3 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1193
Score = 34.7 bits (76), Expect = 2.7
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH PSGFC++N++ + I H ID D+HH
Sbjct: 372 HHCSASYPSGFCWLNNVHVGISHASLTHGLTHAAIIDFDLHH 413
>UniRef50_A2AWS5 Cluster: Histone deacetylase 5; n=21;
Euarchontoglires|Rep: Histone deacetylase 5 - Mus
musculus (Mouse)
Length = 1030
Score = 34.3 bits (75), Expect = 3.5
Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
HHA++ GFC+ N + I +L+ +VL +D D+HH
Sbjct: 740 HHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHH 781
>UniRef50_Q128P1 Cluster: Histone deacetylase superfamily; n=16;
Bacteria|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 337
Score = 34.3 bits (75), Expect = 3.5
Identities = 16/45 (35%), Positives = 22/45 (48%)
Frame = +1
Query: 589 TGASLEGAMKLNNNTCDIAINWSGGLHHAKKFEPSGFCYVNDIVI 723
T A+ A+ +A N +GG HHA + SGFC ND +
Sbjct: 118 TVAAARVALGTGTRPQGVAANMAGGTHHAYAHKGSGFCVFNDSAV 162
>UniRef50_Q9UQL6 Cluster: Histone deacetylase 5; n=141;
Eumetazoa|Rep: Histone deacetylase 5 - Homo sapiens
(Human)
Length = 1122
Score = 34.3 bits (75), Expect = 3.5
Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIA--ILELLKYHPRVLYIDIDVHH 786
HHA++ GFC+ N + I +L+ +VL +D D+HH
Sbjct: 832 HHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHH 873
>UniRef50_Q987Q0 Cluster: Acetylpolyamine aminohydrolase; n=1;
Mesorhizobium loti|Rep: Acetylpolyamine aminohydrolase -
Rhizobium loti (Mesorhizobium loti)
Length = 346
Score = 33.9 bits (74), Expect = 4.7
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLK-YHPRVLYIDIDVHH 786
HHA G+C+VN+ +A LL RV +DID HH
Sbjct: 159 HHAGTDFNGGYCFVNNAAVAAQRLLDGGASRVTILDIDYHH 199
>UniRef50_A5AUM3 Cluster: Putative uncharacterized protein; n=2; Vitis
vinifera|Rep: Putative uncharacterized protein - Vitis
vinifera (Grape)
Length = 1989
Score = 33.9 bits (74), Expect = 4.7
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HHA P FC ++ IA + H RV ID DVHH
Sbjct: 1583 HHAISIGPXDFCVFGNMAIAARYAKRIHELKRVFIIDFDVHH 1624
>UniRef50_Q8WZR5 Cluster: Related to histone deacetylase A; n=4;
Sordariomycetes|Rep: Related to histone deacetylase A -
Neurospora crassa
Length = 747
Score = 33.9 bits (74), Expect = 4.7
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYHP----RVLYIDIDVHH 786
HHA+ P GFC N++ IA +P ++L +D DVHH
Sbjct: 225 HHAEFDAPMGFCLFNNVPIAAKICQTEYPEICRKILILDWDVHH 268
>UniRef50_O27994 Cluster: Acetylpolyamine aminohydrolase, putative;
n=2; Euryarchaeota|Rep: Acetylpolyamine aminohydrolase,
putative - Archaeoglobus fulgidus
Length = 187
Score = 33.9 bits (74), Expect = 4.7
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVH 783
HHA GFCY N+I IA+ +LL + + +D D+H
Sbjct: 41 HHASPDSSWGFCYFNNIAIAVKKLLVEGRIKKAVIVDFDLH 81
>UniRef50_Q94EJ2 Cluster: Histone deacetylase 8; n=14;
Magnoliophyta|Rep: Histone deacetylase 8 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 377
Score = 33.9 bits (74), Expect = 4.7
Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILELLKYH--PRVLYIDIDVHH 786
HH++ + G+C++N+ +A+ L RV IDIDVH+
Sbjct: 144 HHSQPTQADGYCFLNNAALAVKLALNSGSCSRVAVIDIDVHY 185
>UniRef50_A6Q2Z0 Cluster: Acetoin utilization protein; n=1;
Nitratiruptor sp. SB155-2|Rep: Acetoin utilization
protein - Nitratiruptor sp. (strain SB155-2)
Length = 302
Score = 33.5 bits (73), Expect = 6.2
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIV-IAILELLKYHPRVLYIDIDVHH 786
HHA++ GFC N++ +A + +VL ID DVHH
Sbjct: 121 HHAERRTGQGFCIFNNVAFMARYAQKRGFEKVLIIDFDVHH 161
>UniRef50_A4BSQ6 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=1; Nitrococcus mobilis Nb-231|Rep: Histone
deacetylase/AcuC/AphA family protein - Nitrococcus
mobilis Nb-231
Length = 327
Score = 33.5 bits (73), Expect = 6.2
Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILEL-LKYHPR-VLYIDIDVHH 786
HH++ GFC N++ + L+ +Y R + +D DVHH
Sbjct: 144 HHSEPARAMGFCLFNNVAVGALQARCRYAARNIAVVDFDVHH 185
>UniRef50_A0DV77 Cluster: Chromosome undetermined scaffold_65, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_65,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 122
Score = 33.5 bits (73), Expect = 6.2
Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 4/52 (7%)
Frame = +1
Query: 613 MKLNNNTCDIAINWSGGLHHAKKFEPSGFCYV----NDIVIAILELLKYHPR 756
+K N C I + G + K ++P G C++ DI +LE++K H +
Sbjct: 39 LKKNIQKCQITLKELGSIEEQKTYQPVGKCFILKPKKDIANEVLEIIKSHEK 90
>UniRef50_Q7Z8L8 Cluster: Putative HOS3-like histone deacetylase;
n=3; cellular organisms|Rep: Putative HOS3-like histone
deacetylase - Cochliobolus carbonum (Bipolaris zeicola)
Length = 1193
Score = 33.5 bits (73), Expect = 6.2
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)
Frame = +1
Query: 667 HHAKKFEPSGFCYVNDIVIAILE-LLKYH-PRVLYIDIDVHH 786
HH PSGFC++N++ + I ++ Y+ ID D HH
Sbjct: 359 HHCSDDFPSGFCWINNVHVGIEHAIMTYNLTHAAIIDFDPHH 400
>UniRef50_Q74MV2 Cluster: NEQ538; n=1; Nanoarchaeum equitans|Rep:
NEQ538 - Nanoarchaeum equitans
Length = 287
Score = 33.5 bits (73), Expect = 6.2
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 5/45 (11%)
Frame = +1
Query: 667 HHAKKFEPS-----GFCYVNDIVIAILELLKYHPRVLYIDIDVHH 786
HHA K+ + GFC N+ IA L Y RV +DID+HH
Sbjct: 115 HHAGKYGKANAISQGFCIFNNAAIAALN---YKGRVAIVDIDLHH 156
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 751,076,624
Number of Sequences: 1657284
Number of extensions: 15741420
Number of successful extensions: 37359
Number of sequences better than 10.0: 249
Number of HSP's better than 10.0 without gapping: 35631
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37193
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 67085240885
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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