Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0429
(706 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 72 2e-12
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 72 2e-12
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 72 2e-12
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 71 4e-12
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 54 7e-07
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 54 7e-07
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 54 7e-07
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 52 2e-06
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 52 2e-06
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 52 3e-06
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 52 3e-06
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 52 3e-06
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 52 3e-06
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 52 3e-06
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 52 3e-06
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 52 3e-06
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 51 4e-06
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 51 4e-06
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 51 4e-06
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 50 1e-05
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 50 1e-05
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 50 1e-05
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 50 1e-05
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 50 1e-05
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 49 2e-05
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 49 2e-05
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 49 2e-05
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 49 2e-05
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 49 2e-05
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 48 2e-05
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 48 2e-05
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 47 8e-05
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 47 8e-05
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 47 8e-05
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 47 8e-05
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 47 8e-05
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 47 8e-05
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 47 8e-05
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 47 8e-05
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 47 8e-05
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 47 8e-05
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 46 1e-04
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 46 2e-04
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 45 3e-04
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 45 3e-04
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 45 3e-04
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 45 3e-04
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 45 3e-04
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 45 3e-04
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 45 3e-04
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 45 3e-04
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 45 3e-04
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 45 3e-04
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 45 3e-04
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 44 4e-04
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 44 7e-04
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 43 0.001
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 43 0.001
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 42 0.003
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 42 0.003
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 41 0.004
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 40 0.007
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 40 0.009
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 40 0.009
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 40 0.009
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 40 0.009
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 40 0.009
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 39 0.015
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 39 0.015
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 39 0.015
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 39 0.015
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 39 0.015
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 39 0.015
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 39 0.020
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 39 0.020
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 39 0.020
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 39 0.020
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 39 0.020
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 39 0.020
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 39 0.020
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 39 0.020
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 39 0.020
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 39 0.020
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 39 0.020
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 39 0.020
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 39 0.020
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 39 0.020
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 38 0.035
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 38 0.035
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 36 0.14
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 36 0.14
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 36 0.19
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 36 0.19
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 36 0.19
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 36 0.19
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 35 0.25
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 35 0.33
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 35 0.33
AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family... 35 0.33
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 34 0.57
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 33 0.75
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 32 1.7
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 32 1.7
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 32 1.7
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 32 2.3
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 32 2.3
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 32 2.3
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 32 2.3
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 32 2.3
BC139728-1|AAI39729.1| 250|Homo sapiens C10orf27 protein protein. 32 2.3
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 32 2.3
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 32 2.3
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 32 2.3
AL358817-2|CAI13855.1| 351|Homo sapiens chromosome 10 open read... 32 2.3
AK057382-1|BAB71459.1| 351|Homo sapiens protein ( Homo sapiens ... 32 2.3
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 32 2.3
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 32 2.3
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 32 2.3
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 32 2.3
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 31 3.0
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 31 3.0
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 31 4.0
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 31 4.0
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 31 4.0
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 31 4.0
BC127112-1|AAI27113.1| 1485|Homo sapiens aquarius homolog (mouse... 31 5.3
BC127111-1|AAI27112.1| 1485|Homo sapiens aquarius homolog (mouse... 31 5.3
AB011132-1|BAA25486.3| 1521|Homo sapiens KIAA0560 protein protein. 31 5.3
BC038808-1|AAH38808.1| 373|Homo sapiens apolipoprotein B mRNA e... 30 7.0
X98330-1|CAA66975.1| 4967|Homo sapiens ryanodine receptor 2 prot... 30 9.3
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 30 9.3
DQ146365-1|AAZ38720.1| 373|Homo sapiens apolipoprotein B mRNA e... 30 9.3
BC016559-1|AAH16559.1| 587|Homo sapiens SAC1 suppressor of acti... 30 9.3
AL513130-1|CAI15936.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AL445473-1|CAH71393.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AL442065-1|CAI15350.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AL391809-1|CAI14440.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AL365332-1|CAH71369.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AL359924-1|CAI22065.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AL356773-1|CAH73918.1| 4965|Homo sapiens ryanodine receptor 2 (c... 30 9.3
AJ300340-1|CAC18855.1| 4967|Homo sapiens ryanodine receptor 2 pr... 30 9.3
AJ297357-2|CAB95945.1| 542|Homo sapiens KIAA0851 protein protein. 30 9.3
AJ289880-1|CAB96871.1| 426|Homo sapiens KIAA0851 protein protein. 30 9.3
AB020658-1|BAA74874.2| 607|Homo sapiens KIAA0851 protein protein. 30 9.3
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/151 (28%), Positives = 81/151 (53%), Gaps = 3/151 (1%)
Frame = +3
Query: 198 PLLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFV-FWLGPRPILFISDPEDVKGV--NN 368
PL+G+ + + FQ + I T + MP + W+GP P++ + + E+V+ + ++
Sbjct: 58 PLVGHALLMKPDGREFFQQI--IEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSS 115
Query: 369 AFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ 548
I+K Y F + WLG GL+ + W++ K L+ TF +I+E + ++ +A LV+
Sbjct: 116 KQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVK 175
Query: 549 RLKARTTEEPFDIMHDLAYTTLEAICQTAFG 641
+L+ +E F+ + L+ IC+TA G
Sbjct: 176 KLEKHINQEAFNCFFYITLCALDIICETAMG 206
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/151 (28%), Positives = 81/151 (53%), Gaps = 3/151 (1%)
Frame = +3
Query: 198 PLLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFV-FWLGPRPILFISDPEDVKGV--NN 368
PL+G+ + + FQ + I T + MP + W+GP P++ + + E+V+ + ++
Sbjct: 58 PLVGHALLMKPDGREFFQQI--IEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSS 115
Query: 369 AFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ 548
I+K Y F + WLG GL+ + W++ K L+ TF +I+E + ++ +A LV+
Sbjct: 116 KQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVK 175
Query: 549 RLKARTTEEPFDIMHDLAYTTLEAICQTAFG 641
+L+ +E F+ + L+ IC+TA G
Sbjct: 176 KLEKHINQEAFNCFFYITLCALDIICETAMG 206
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 72.1 bits (169), Expect = 2e-12
Identities = 43/151 (28%), Positives = 81/151 (53%), Gaps = 3/151 (1%)
Frame = +3
Query: 198 PLLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFV-FWLGPRPILFISDPEDVKGV--NN 368
PL+G+ + + FQ + I T + MP + W+GP P++ + + E+V+ + ++
Sbjct: 58 PLVGHALLMKPDGREFFQQI--IEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSS 115
Query: 369 AFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ 548
I+K Y F + WLG GL+ + W++ K L+ TF +I+E + ++ +A LV+
Sbjct: 116 KQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVK 175
Query: 549 RLKARTTEEPFDIMHDLAYTTLEAICQTAFG 641
+L+ +E F+ + L+ IC+TA G
Sbjct: 176 KLEKHINQEAFNCFFYITLCALDIICETAMG 206
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 70.9 bits (166), Expect = 4e-12
Identities = 39/133 (29%), Positives = 73/133 (54%), Gaps = 3/133 (2%)
Frame = +3
Query: 252 FLEKIAVTCDTTEMPFV-FWLGPRPILFISDPEDVKGV--NNAFIEKPHYYSFAKVWLGN 422
F + I T + MP + W+GP P++ + + E+V+ + ++ I+K Y F + WLG
Sbjct: 52 FQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGL 111
Query: 423 GLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTEEPFDIMHDLA 602
GL+ + W++ K L+ TF +I+E + ++ +A LV++L+ +E F+ +
Sbjct: 112 GLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYIT 171
Query: 603 YTTLEAICQTAFG 641
L+ IC+TA G
Sbjct: 172 LCALDIICETAMG 184
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 53.6 bits (123), Expect = 7e-07
Identities = 45/168 (26%), Positives = 81/168 (48%), Gaps = 12/168 (7%)
Frame = +3
Query: 177 LPSFPQLP----LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISD 341
L FPQ P LLG++ N L Q +K+ D + W+GP P+L +
Sbjct: 56 LRCFPQPPRRNWLLGHLGMYLPNEAGL-QDEKKVL---DNMHHVLLVWMGPVLPLLVLVH 111
Query: 342 PEDVK---GVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
P+ +K G + A K +Y F K WLG+GL+++ + W + L+ F I++ Y
Sbjct: 112 PDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPY 171
Query: 510 QEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQTAFGF 644
++F ++AD++ R A + D+ ++ TL+++ + F +
Sbjct: 172 MKIF-NQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSY 218
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 53.6 bits (123), Expect = 7e-07
Identities = 45/168 (26%), Positives = 81/168 (48%), Gaps = 12/168 (7%)
Frame = +3
Query: 177 LPSFPQLP----LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISD 341
L FPQ P LLG++ N L Q +K+ D + W+GP P+L +
Sbjct: 56 LRCFPQPPRRNWLLGHLGMYLPNEAGL-QDEKKVL---DNMHHVLLVWMGPVLPLLVLVH 111
Query: 342 PEDVK---GVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
P+ +K G + A K +Y F K WLG+GL+++ + W + L+ F I++ Y
Sbjct: 112 PDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPY 171
Query: 510 QEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQTAFGF 644
++F ++AD++ R A + D+ ++ TL+++ + F +
Sbjct: 172 MKIF-NQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSY 218
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 53.6 bits (123), Expect = 7e-07
Identities = 45/168 (26%), Positives = 81/168 (48%), Gaps = 12/168 (7%)
Frame = +3
Query: 177 LPSFPQLP----LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISD 341
L FPQ P LLG++ N L Q +K+ D + W+GP P+L +
Sbjct: 56 LRCFPQPPRRNWLLGHLGMYLPNEAGL-QDEKKVL---DNMHHVLLVWMGPVLPLLVLVH 111
Query: 342 PEDVK---GVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
P+ +K G + A K +Y F K WLG+GL+++ + W + L+ F I++ Y
Sbjct: 112 PDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPY 171
Query: 510 QEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQTAFGF 644
++F ++AD++ R A + D+ ++ TL+++ + F +
Sbjct: 172 MKIF-NQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSY 218
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/168 (26%), Positives = 81/168 (48%), Gaps = 12/168 (7%)
Frame = +3
Query: 177 LPSFPQLP----LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISD 341
L FPQ P LLG++ N L Q +K+ D + W+GP P+L +
Sbjct: 56 LRCFPQPPRRNWLLGHLGMYLPNEAGL-QDEKKVL---DNMHHVLLVWMGPVLPLLVLVH 111
Query: 342 PEDVK---GVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
P+ +K G + A K +Y F K WLG+GL+++ + W + L+ F I++ Y
Sbjct: 112 PDYIKPLLGASAATAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPY 171
Query: 510 QEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQTAFGF 644
++F ++AD++ R A + D+ ++ TL+++ + F +
Sbjct: 172 MKIF-NQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSY 218
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/207 (24%), Positives = 89/207 (42%), Gaps = 15/207 (7%)
Frame = +3
Query: 69 LSMLIMSEVLWCLLMLCACVWWWCSAPRRTRKLL---AALPSFPQLP----LLGNIHQIP 227
L + M+ W LL+L W T L FPQ P LG++ +
Sbjct: 9 LGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLVT 68
Query: 228 RNSINLFQFLEKIAVTCDTTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPH-Y 392
+ + +A T F W+GP P++ P ++ V NA + K +
Sbjct: 69 PTEQGMRVLTQLVA----TYPQGFKVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVF 124
Query: 393 YSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKAR 563
YSF K WLG+GL+++ E W + L+ F +I++ Y ++F + +++ +L A
Sbjct: 125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLAS 183
Query: 564 TTEEPFDIMHDLAYTTLEAICQTAFGF 644
D+ ++ TL+++ + F F
Sbjct: 184 KGYARLDMFEHISLMTLDSLQKCVFSF 210
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 52.0 bits (119), Expect = 2e-06
Identities = 35/124 (28%), Positives = 68/124 (54%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNN---AFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNS 461
FV WLGP PI+ + P+ V+ V N A +K +Y K WLG+GL+++ + W++
Sbjct: 88 FVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP---FDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F+ ++A+++ R E D+ ++ TL+++ +
Sbjct: 148 RRLLTPAFHFNILKPYIKIFS-KSANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 IFSF 210
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F + +++ +L A D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 51.2 bits (117), Expect = 4e-06
Identities = 30/123 (24%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP--FDIMHDLAYTTLEAICQTA 635
+ L+ F +I++ Y ++F + + + +E D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCV 207
Query: 636 FGF 644
F F
Sbjct: 208 FSF 210
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 51.2 bits (117), Expect = 4e-06
Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGPR-PILFISDPEDVKGVNNAFIE-KPH---YYSFAKVWLGNGLVVAPPEIWKNS 461
F WLGP P+L + P+ ++ + +A P +Y F K WLG+GL+++ + W
Sbjct: 88 FKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVF---AGRAADLVQRLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F D QRL + + D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSAR-LDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 51.2 bits (117), Expect = 4e-06
Identities = 33/124 (26%), Positives = 62/124 (50%), Gaps = 8/124 (6%)
Frame = +3
Query: 297 FVFWLGPR-PILFISDPEDVKGVNNAFIE-KPH---YYSFAKVWLGNGLVVAPPEIWKNS 461
F WLGP P+L + P+ ++ + +A P +Y F K WLG+GL+++ + W
Sbjct: 88 FKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVF---AGRAADLVQRLKARTTEEPFDIMHDLAYTTLEAICQT 632
+ L+ F +I++ Y ++F D QRL + + D+ ++ TL+++ +
Sbjct: 148 RRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSAR-LDMFEHISLMTLDSLQKC 206
Query: 633 AFGF 644
F F
Sbjct: 207 VFSF 210
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Frame = +3
Query: 69 LSMLIMSEVLWCLLMLCACVWWWCSAPRRTRKLL---AALPSFPQLP----LLGNIHQIP 227
L + M+ W LL+L W T L FPQ P LG++ I
Sbjct: 9 LGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIH 68
Query: 228 RNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISDPEDVKGV---NNAFIEKPH-Y 392
+ L + + +A C +M +W+GP I+ I P +K V A + K +
Sbjct: 69 SSEEGLL-YTQSLA--CTFGDM-CCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF 124
Query: 393 YSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKAR 563
YSF K WLG+GL+++ E W + L+ F +I++ Y ++F + +++ +L A
Sbjct: 125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLAS 183
Query: 564 TTEEPFDIMHDLAYTTLEAICQTAFGF 644
D+ ++ TL+++ + F F
Sbjct: 184 EGSARLDMFEHISLMTLDSLQKCVFSF 210
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Frame = +3
Query: 69 LSMLIMSEVLWCLLMLCACVWWWCSAPRRTRKLL---AALPSFPQLP----LLGNIHQIP 227
L + M+ W LL+L W T L FPQ P LG++ I
Sbjct: 9 LGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIH 68
Query: 228 RNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISDPEDVKGV---NNAFIEKPH-Y 392
+ L + + +A C +M +W+GP I+ I P +K V A + K +
Sbjct: 69 SSEEGLL-YTQSLA--CTFGDM-CCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF 124
Query: 393 YSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKAR 563
YSF K WLG+GL+++ E W + L+ F +I++ Y ++F + +++ +L A
Sbjct: 125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLAS 183
Query: 564 TTEEPFDIMHDLAYTTLEAICQTAFGF 644
D+ ++ TL+++ + F F
Sbjct: 184 EGSARLDMFEHISLMTLDSLQKCVFSF 210
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Frame = +3
Query: 69 LSMLIMSEVLWCLLMLCACVWWWCSAPRRTRKLL---AALPSFPQLP----LLGNIHQIP 227
L + M+ W LL+L W T L FPQ P LG++ I
Sbjct: 9 LGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIH 68
Query: 228 RNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISDPEDVKGV---NNAFIEKPH-Y 392
+ L + + +A C +M +W+GP I+ I P +K V A + K +
Sbjct: 69 SSEEGLL-YTQSLA--CTFGDM-CCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF 124
Query: 393 YSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKAR 563
YSF K WLG+GL+++ E W + L+ F +I++ Y ++F + +++ +L A
Sbjct: 125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLAS 183
Query: 564 TTEEPFDIMHDLAYTTLEAICQTAFGF 644
D+ ++ TL+++ + F F
Sbjct: 184 EGSARLDMFEHISLMTLDSLQKCVFSF 210
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Frame = +3
Query: 69 LSMLIMSEVLWCLLMLCACVWWWCSAPRRTRKLL---AALPSFPQLP----LLGNIHQIP 227
L + M+ W LL+L W T L FPQ P LG++ I
Sbjct: 9 LGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIH 68
Query: 228 RNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISDPEDVKGV---NNAFIEKPH-Y 392
+ L + + +A C +M +W+GP I+ I P +K V A + K +
Sbjct: 69 SSEEGLL-YTQSLA--CTFGDM-CCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF 124
Query: 393 YSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKAR 563
YSF K WLG+GL+++ E W + L+ F +I++ Y ++F + +++ +L A
Sbjct: 125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLAS 183
Query: 564 TTEEPFDIMHDLAYTTLEAICQTAFGF 644
D+ ++ TL+++ + F F
Sbjct: 184 EGSARLDMFEHISLMTLDSLQKCVFSF 210
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 49.6 bits (113), Expect = 1e-05
Identities = 53/207 (25%), Positives = 92/207 (44%), Gaps = 15/207 (7%)
Frame = +3
Query: 69 LSMLIMSEVLWCLLMLCACVWWWCSAPRRTRKLL---AALPSFPQLP----LLGNIHQIP 227
L + M+ W LL+L W T L FPQ P LG++ I
Sbjct: 9 LGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIH 68
Query: 228 RNSINLFQFLEKIAVTCDTTEMPFVFWLGP-RPILFISDPEDVKGV---NNAFIEKPH-Y 392
+ L + + +A C +M +W+GP I+ I P +K V A + K +
Sbjct: 69 SSEEGLL-YTQSLA--CTFGDM-CCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF 124
Query: 393 YSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQ---RLKAR 563
YSF K WLG+GL+++ E W + L+ F +I++ Y ++F + +++ +L A
Sbjct: 125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIF-NESVNIMHAKWQLLAS 183
Query: 564 TTEEPFDIMHDLAYTTLEAICQTAFGF 644
D+ ++ TL+++ + F F
Sbjct: 184 EGSARLDMFEHISLMTLDSLQKCVFSF 210
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Frame = +3
Query: 282 TTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPHYY-SFAKVWLGNGLVVAPPE 446
T F WLGP P + + P+ ++ + NA K + + F K WLG G++++ +
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 447 IWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTE--EPFDIMHDLAYTTLEA 620
W + L+ F +I++ Y +F A ++ + + +E D+ ++ TL++
Sbjct: 143 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDS 202
Query: 621 ICQTAFGF 644
+ + F F
Sbjct: 203 LQKCIFSF 210
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Frame = +3
Query: 282 TTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPHYY-SFAKVWLGNGLVVAPPE 446
T F WLGP P + + P+ ++ + NA K + + F K WLG G++++ +
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 447 IWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTE--EPFDIMHDLAYTTLEA 620
W + L+ F +I++ Y +F A ++ + + +E D+ ++ TL++
Sbjct: 143 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDS 202
Query: 621 ICQTAFGF 644
+ + F F
Sbjct: 203 LQKCIFSF 210
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Frame = +3
Query: 282 TTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPHYY-SFAKVWLGNGLVVAPPE 446
T F WLGP P + + P+ ++ + NA K + + F K WLG G++++ +
Sbjct: 17 TYSQGFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 76
Query: 447 IWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTE--EPFDIMHDLAYTTLEA 620
W + L+ F +I++ Y +F A ++ + + +E D+ ++ TL++
Sbjct: 77 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDS 136
Query: 621 ICQTAFGF 644
+ + F F
Sbjct: 137 LQKCIFSF 144
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Frame = +3
Query: 282 TTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPHYY-SFAKVWLGNGLVVAPPE 446
T F WLGP P + + P+ ++ + NA K + + F K WLG G++++ +
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 447 IWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTE--EPFDIMHDLAYTTLEA 620
W + L+ F +I++ Y +F A ++ + + +E D+ ++ TL++
Sbjct: 143 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDS 202
Query: 621 ICQTAFGF 644
+ + F F
Sbjct: 203 LQKCIFSF 210
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Frame = +3
Query: 282 TTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPHYY-SFAKVWLGNGLVVAPPE 446
T F WLGP P + + P+ ++ + NA K + + F K WLG G++++ +
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 447 IWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTE--EPFDIMHDLAYTTLEA 620
W + L+ F +I++ Y +F A ++ + + +E D+ ++ TL++
Sbjct: 143 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDS 202
Query: 621 ICQTAFGF 644
+ + F F
Sbjct: 203 LQKCIFSF 210
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 48.4 bits (110), Expect = 2e-05
Identities = 30/128 (23%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Frame = +3
Query: 282 TTEMPFVFWLGPR-PILFISDPEDVKGVNNA---FIEKPHYY-SFAKVWLGNGLVVAPPE 446
T F WLGP P + + P+ ++ + NA K + + F K WLG G++++ +
Sbjct: 83 TYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142
Query: 447 IWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTE--EPFDIMHDLAYTTLEA 620
W + L+ F +I++ Y +F A ++ + + +E D+ ++ TL++
Sbjct: 143 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDS 202
Query: 621 ICQTAFGF 644
+ + F F
Sbjct: 203 LQKCIFSF 210
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 48.4 bits (110), Expect = 2e-05
Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Frame = +3
Query: 297 FVFWLGP-RPILFISDPEDVKGVNNAFI----EKPHYYSFAKVWLGNGLVVAPPEIWKNS 461
F W+GP P+L + P+ ++ V NA + +YSF + WLG+GL+++ + W
Sbjct: 88 FKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRH 147
Query: 462 IKKLSGTFTPSIVEGYQEVF 521
+ L+ F +I++ Y ++F
Sbjct: 148 RRMLTPAFHFNILKPYMKIF 167
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 46.8 bits (106), Expect = 8e-05
Identities = 42/175 (24%), Positives = 78/175 (44%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I + AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRN 213
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 46.4 bits (105), Expect = 1e-04
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R R L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRRTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 6/164 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I ++ ++ Q L++I +T WL G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQELQQD-----QELQRIQKWVETFPSACPHWLWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAF 638
+ A ++ + + ++ P ++ ++ TL+ I + AF
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAF 202
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 6/169 (3%)
Frame = +3
Query: 153 RTRKLLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWLGPR- 320
R + L A+ FP P L G+ +I L+K+ W G
Sbjct: 35 RRQTLAKAMDKFPGPPTHWLFGHALEIQETGS-----LDKVVSWAHQFPYAHPLWFGQFI 89
Query: 321 PILFISDPEDVKGVNNAFIEK-PHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSI 497
L I +P+ K V + K P Y F W+G GL+V W K L+ F +
Sbjct: 90 GFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDV 149
Query: 498 VEGYQEVFAGRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
++ Y VF ++ + + + E + FDI D+ + L + + FG
Sbjct: 150 LKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKCTFG 198
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 43.6 bits (98), Expect = 7e-04
Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G L++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDSKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P + ++ TL+ I ++AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSIQVDRN 213
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G L++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P + ++ TL+ I ++AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSIQVDRN 213
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F W+G L++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P + ++ TL+ I ++AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSIQVDRN 213
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F +G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I ++AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRN 213
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F +G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I ++AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRN 213
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 41.1 bits (92), Expect = 0.004
Identities = 40/175 (22%), Positives = 76/175 (43%), Gaps = 6/175 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F +G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYRFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAFGFPKIFREHRN 671
+ A ++ + + ++ P ++ ++ TL+ I ++AF + RN
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRN 213
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 40.3 bits (90), Expect = 0.007
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F +G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAF 638
+ A ++ + + ++ P ++ ++ TL+ I ++AF
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 39.9 bits (89), Expect = 0.009
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Frame = +3
Query: 318 RPILFISDPEDVKGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFT 488
+P+L I+DP+ +K V + + F V ++ N + +A E WK LS TFT
Sbjct: 79 QPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFT 138
Query: 489 PSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
++ + A LV+ L+ T +P + H +++ I T+FG
Sbjct: 139 SGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFG 190
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 39.9 bits (89), Expect = 0.009
Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 6/164 (3%)
Frame = +3
Query: 165 LLAALPSFPQLP---LLGNIHQIPRNSINLFQFLEKIAVTCDTTEMPFVFWL-GPRPILF 332
LL AL FP P L G+I + + Q L++I T +W+ G + +
Sbjct: 44 LLKALQQFPCPPSHWLFGHIQEFQHD-----QELQRIQERVKTFPSACPYWIWGGKVRVQ 98
Query: 333 ISDPEDVKGVNNAFIEKPH-YYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGY 509
+ DP+ +K + K H Y F +G GL++ + W + L+ F I++ Y
Sbjct: 99 LYDPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPY 158
Query: 510 QEVFAGRAADLVQRLKARTTEE-PFDIMHDLAYTTLEAICQTAF 638
+ A ++ + + ++ P ++ ++ TL+ I ++AF
Sbjct: 159 VGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 39.9 bits (89), Expect = 0.009
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Frame = +3
Query: 318 RPILFISDPEDVKGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFT 488
+P+L I+DP+ +K V + + F V ++ N + +A E WK LS TFT
Sbjct: 79 QPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFT 138
Query: 489 PSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
++ + A LV+ L+ T +P + H +++ I T+FG
Sbjct: 139 SGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFG 190
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 39.9 bits (89), Expect = 0.009
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Frame = +3
Query: 318 RPILFISDPEDVKGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFT 488
+P+L I+DP+ +K V + + F V ++ N + +A E WK LS TFT
Sbjct: 79 QPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFT 138
Query: 489 PSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
++ + A LV+ L+ T +P + H +++ I T+FG
Sbjct: 139 SGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFG 190
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 39.9 bits (89), Expect = 0.009
Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Frame = +3
Query: 318 RPILFISDPEDVKGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFT 488
+P+L I+DP+ +K V + + F V ++ N + +A E WK LS TFT
Sbjct: 79 QPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFT 138
Query: 489 PSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
++ + A LV+ L+ T +P + H +++ I T+FG
Sbjct: 139 SGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFG 190
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.015
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 66 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 125
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 126 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 185
Query: 603 YTTLEAICQTAF 638
+L+ I + AF
Sbjct: 186 SMSLDIIMKCAF 197
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.015
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 66 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 125
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 126 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 185
Query: 603 YTTLEAICQTAF 638
+L+ I + AF
Sbjct: 186 SMSLDIIMKCAF 197
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.015
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 66 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 125
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 126 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 185
Query: 603 YTTLEAICQTAF 638
+L+ I + AF
Sbjct: 186 SMSLDIIMKCAF 197
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.015
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 66 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 125
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 126 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 185
Query: 603 YTTLEAICQTAF 638
+L+ I + AF
Sbjct: 186 SMSLDIIMKCAF 197
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 39.1 bits (87), Expect = 0.015
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 66 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 125
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 126 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 185
Query: 603 YTTLEAICQTAF 638
+L+ I + AF
Sbjct: 186 SMSLDIIMKCAF 197
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 39.1 bits (87), Expect = 0.015
Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 1 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 60
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 61 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 120
Query: 603 YTTLEAICQTAF 638
+L+ I + AF
Sbjct: 121 SMSLDIIMKCAF 132
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 38.7 bits (86), Expect = 0.020
Identities = 31/132 (23%), Positives = 56/132 (42%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 LEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGL 428
+EK+ + F FW+GP F I DP+ K + + K Y F+ LG GL
Sbjct: 65 MEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGL 124
Query: 429 VVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLK--ARTTEEPFDIMHDLA 602
W + L+ F +I++ Y EV A ++ + + T + ++ +
Sbjct: 125 AALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHIN 184
Query: 603 YTTLEAICQTAF 638
+L+ + + AF
Sbjct: 185 SMSLDIVMKCAF 196
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 1 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 60
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 61 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 117
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVKG--VNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRLKART-TEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L+ T +P + +++ I T+FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFG 190
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 37.9 bits (84), Expect = 0.035
Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVK--GVNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRL-KARTTEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L + R T +P + +++ I ++FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFG 190
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 37.9 bits (84), Expect = 0.035
Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 4/117 (3%)
Frame = +3
Query: 303 FWLGPRPILFISDPEDVK--GVNNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKL 473
F+ G +P+L I+DP+ +K V + + F V ++ + + +A E WK L
Sbjct: 74 FYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDEEWKRLRSLL 133
Query: 474 SGTFTPSIVEGYQEVFAGRAADLVQRL-KARTTEEPFDIMHDLAYTTLEAICQTAFG 641
S TFT ++ + A LV+ L + R T +P + +++ I ++FG
Sbjct: 134 SPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFG 190
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 35.9 bits (79), Expect = 0.14
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 12/167 (7%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ + E
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLCGVE 82
Query: 348 DVKG--VNN--AFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEG--- 506
++ V+N AF + V+ G G++ A WK +++ S T G
Sbjct: 83 AIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWK-VLRRFSVTTMRDFGMGKRS 141
Query: 507 YQEVFAGRAADLVQRLKAR--TTEEPFDIMHDLAYTTLEAICQTAFG 641
+E A L++ L+ +P + H + T IC FG
Sbjct: 142 VEERIQDEAQCLIEELRKSKGALVDPTFLFHSI---TANIICSIIFG 185
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 35.9 bits (79), Expect = 0.14
Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 12/167 (7%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ + E
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLCGVE 82
Query: 348 DVKG--VNN--AFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEG--- 506
++ V+N AF + V+ G G++ A WK +++ S T G
Sbjct: 83 AIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWK-VLRRFSVTTMRDFGMGKRS 141
Query: 507 YQEVFAGRAADLVQRLKAR--TTEEPFDIMHDLAYTTLEAICQTAFG 641
+E A L++ L+ +P + H + T IC FG
Sbjct: 142 VEERIQDEAQCLIEELRKSKGALVDPTFLFHSI---TANIICSIIFG 185
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 35.5 bits (78), Expect = 0.19
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 8/189 (4%)
Frame = +3
Query: 99 WCLLMLCACVWWWCSAPRRTRKLLAALPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC 278
W LL+ A + A TR P LPLLGN+ Q+ + L+ L +++
Sbjct: 7 WALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGA--LYSGLMRLSKKY 64
Query: 279 DTTEMPFVFWLGP-RPILFISDPEDVK----GVNNAFIEKPHYYSFAKVWLGNGLVVAPP 443
F +LGP RP++ + E V+ G F + + G+G+ +
Sbjct: 65 GPV---FTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNG 121
Query: 444 EIWKNSIKKLSGTFTPSIVEGY---QEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTL 614
E W+ ++K + + G +E+ A LV+ + T PFD LA T
Sbjct: 122 ERWR-QLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQG-TEGRPFDPSLLLAQATS 179
Query: 615 EAICQTAFG 641
+C FG
Sbjct: 180 NVVCSLLFG 188
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 35.5 bits (78), Expect = 0.19
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 8/189 (4%)
Frame = +3
Query: 99 WCLLMLCACVWWWCSAPRRTRKLLAALPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC 278
W LL+ A + A TR P LPLLGN+ Q+ + L+ L +++
Sbjct: 7 WALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGA--LYSGLMRLSKKY 64
Query: 279 DTTEMPFVFWLGP-RPILFISDPEDVK----GVNNAFIEKPHYYSFAKVWLGNGLVVAPP 443
F +LGP RP++ + E V+ G F + + G+G+ +
Sbjct: 65 GPV---FTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNG 121
Query: 444 EIWKNSIKKLSGTFTPSIVEGY---QEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTL 614
E W+ ++K + + G +E+ A LV+ + T PFD LA T
Sbjct: 122 ERWR-QLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQG-TEGRPFDPSLLLAQATS 179
Query: 615 EAICQTAFG 641
+C FG
Sbjct: 180 NVVCSLLFG 188
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 35.5 bits (78), Expect = 0.19
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 8/189 (4%)
Frame = +3
Query: 99 WCLLMLCACVWWWCSAPRRTRKLLAALPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC 278
W LL+ A + A TR P LPLLGN+ Q+ + L+ L +++
Sbjct: 7 WALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGA--LYSGLMRLSKKY 64
Query: 279 DTTEMPFVFWLGP-RPILFISDPEDVK----GVNNAFIEKPHYYSFAKVWLGNGLVVAPP 443
F +LGP RP++ + E V+ G F + + G+G+ +
Sbjct: 65 GPV---FTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNG 121
Query: 444 EIWKNSIKKLSGTFTPSIVEGY---QEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTL 614
E W+ ++K + + G +E+ A LV+ + T PFD LA T
Sbjct: 122 ERWR-QLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQG-TEGRPFDPSLLLAQATS 179
Query: 615 EAICQTAFG 641
+C FG
Sbjct: 180 NVVCSLLFG 188
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 35.5 bits (78), Expect = 0.19
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 8/189 (4%)
Frame = +3
Query: 99 WCLLMLCACVWWWCSAPRRTRKLLAALPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC 278
W LL+ A + A TR P LPLLGN+ Q+ + L+ L +++
Sbjct: 7 WALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGA--LYSGLMRLSKKY 64
Query: 279 DTTEMPFVFWLGP-RPILFISDPEDVK----GVNNAFIEKPHYYSFAKVWLGNGLVVAPP 443
F +LGP RP++ + E V+ G F + + G+G+ +
Sbjct: 65 GPV---FTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNG 121
Query: 444 EIWKNSIKKLSGTFTPSIVEGY---QEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTL 614
E W+ ++K + + G +E+ A LV+ + T PFD LA T
Sbjct: 122 ERWR-QLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQG-TEGRPFDPSLLLAQATS 179
Query: 615 EAICQTAFG 641
+C FG
Sbjct: 180 NVVCSLLFG 188
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 35.1 bits (77), Expect = 0.25
Identities = 50/202 (24%), Positives = 86/202 (42%), Gaps = 8/202 (3%)
Frame = +3
Query: 105 LLMLCACVWWWCSAPRRTRKLLAALPSFPQ-LPLLGNIHQIPRNSINLFQFLEKIAVTCD 281
LL+L A V + R + LP P+ LP+LGN+ + S ++ L K++
Sbjct: 9 LLLLLALVCLLLTLSSRDK---GKLPPGPRPLPILGNLLLLC--SQDMLTSLTKLSKEYG 63
Query: 282 TTEMPFVFWLGPRPILFISDPEDVKGV----NNAFIEKPHYYSFAKVWLGNGLVVAPPEI 449
+ + LGPR ++ +S + VK F + Y +F GNG+ + +
Sbjct: 64 SM---YTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDR 120
Query: 450 WKNSIKKLSGTFTPSIVEG---YQEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTLEA 620
WK +++ S + G +E + L+ L+ +T EPFD L+ +
Sbjct: 121 WK-VLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELR-KTEGEPFDPTFVLSRSVSNI 178
Query: 621 ICQTAFGFPKIFREHRN*RILR 686
IC FG + + R I+R
Sbjct: 179 ICSVLFGSRFDYDDERLLTIIR 200
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 34.7 bits (76), Expect = 0.33
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +3
Query: 399 FAKVWLGNGLVV-APPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTT-E 572
F + G GLV E W + + F+ S + E F +A LV+ L+A+ +
Sbjct: 116 FGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQ 175
Query: 573 EPFDIMHDLAYTTLEAICQTAFG 641
P + L YT ++ + + AFG
Sbjct: 176 TPVSMQDMLTYTAMDILAKAAFG 198
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 34.7 bits (76), Expect = 0.33
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +3
Query: 399 FAKVWLGNGLVV-APPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTT-E 572
F + G GLV E W + + F+ S + E F +A LV+ L+A+ +
Sbjct: 116 FGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQ 175
Query: 573 EPFDIMHDLAYTTLEAICQTAFG 641
P + L YT ++ + + AFG
Sbjct: 176 TPVSMQDMLTYTAMDILAKAAFG 198
>AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family 46
variant protein.
Length = 210
Score = 34.7 bits (76), Expect = 0.33
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +3
Query: 399 FAKVWLGNGLVV-APPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTT-E 572
F + G GLV E W + + F+ S + E F +A LV+ L+A+ +
Sbjct: 87 FGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQ 146
Query: 573 EPFDIMHDLAYTTLEAICQTAFG 641
P + L YT ++ + + AFG
Sbjct: 147 TPVSMQDMLTYTAMDILAKAAFG 169
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 33.9 bits (74), Expect = 0.57
Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 15/170 (8%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ +
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLC--- 79
Query: 348 DVKGVNNAFIEKPHYYS----FAKV---WLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEG 506
V+ + A ++K +S A V + G G++ A WK +++ S T G
Sbjct: 80 GVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWK-VLRRFSVTTMRDFGMG 138
Query: 507 ---YQEVFAGRAADLVQRLKAR--TTEEPFDIMHDLAYTTLEAICQTAFG 641
+E A L++ L+ +P + H + T IC FG
Sbjct: 139 KRSVEERIQEEAQCLIEELRKSKGALMDPTFLFHSI---TANIICSIVFG 185
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 33.5 bits (73), Expect = 0.75
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 9/195 (4%)
Frame = +3
Query: 81 IMSEVLWCLLMLCACVWWW--CSAPRRTRKLLAALPSFPQLP---LLGNIHQIPRNSINL 245
+M+ L++LC + + RR R + A+ FP P G+ P +
Sbjct: 9 LMAHPFLLLILLCMSLLLFQVIRLYRRRRWTIRAMHLFPAPPAHWFYGHKESYPVKEFEV 68
Query: 246 F-QFLEKIAVTCDTTEMPFVFWLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWL 416
+ + +EK +P W+GP + F I DP+ VK + K + + W+
Sbjct: 69 YPELMEKYPCA-----VPL--WVGPFTMFFNIHDPDYVKILLKRQDPKSAVSHKILESWV 121
Query: 417 GNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP-FDIMH 593
G GLV WK + + F SI++ + + + ++ + + + ++
Sbjct: 122 GRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQ 181
Query: 594 DLAYTTLEAICQTAF 638
++ TL++I + AF
Sbjct: 182 HVSLMTLDSIMKCAF 196
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 32.3 bits (70), Expect = 1.7
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Frame = +3
Query: 375 IEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRL 554
I +P Y G GL+V W K L+ F +++ Y VF ++ +
Sbjct: 94 IYEPDYAKAVYSRGGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKW 153
Query: 555 KARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
+ + E + FDI D+ + L + + FG
Sbjct: 154 EEKAREGKSFDIFCDVGHMALNTLMKCTFG 183
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 32.3 bits (70), Expect = 1.7
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Frame = +3
Query: 375 IEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRL 554
I +P Y G GL+V W K L+ F +++ Y VF ++ +
Sbjct: 94 IYEPDYAKAVYSRGGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKW 153
Query: 555 KARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
+ + E + FDI D+ + L + + FG
Sbjct: 154 EEKAREGKSFDIFCDVGHMALNTLMKCTFG 183
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 32.3 bits (70), Expect = 1.7
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
Frame = +3
Query: 375 IEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFAGRAADLVQRL 554
I +P Y G GL+V W K L+ F +++ Y VF ++ +
Sbjct: 94 IYEPDYAKAVYSRGGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKW 153
Query: 555 KARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
+ + E + FDI D+ + L + + FG
Sbjct: 154 EEKAREGKSFDIFCDVGHMALNTLMKCTFG 183
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 31.9 bits (69), Expect = 2.3
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ +
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLC--- 79
Query: 348 DVKGVNNAFIEKPHYYS 398
V+ + A ++K +S
Sbjct: 80 GVEAIREALVDKAEAFS 96
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 31.9 bits (69), Expect = 2.3
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 177 LPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC-DTTEMPFVFWLGPRPILFISDPEDV 353
+P LPLLGN+ ++ Q L K C + + G P+L I+DP+ +
Sbjct: 38 IPGPTPLPLLGNV-------LSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 354 KGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFA 524
+ V + + S V ++ + + +A E WK LS TFT ++ + A
Sbjct: 91 RTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIA 150
Query: 525 GRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
LV+ L+ + +P + +++ I T+FG
Sbjct: 151 QYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFG 190
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 31.9 bits (69), Expect = 2.3
Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +3
Query: 309 LGPRPILFISDPEDVKGV----NNAFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLS 476
LGPR ++ +S + VK F + Y +F GNG+ + + WK +++ S
Sbjct: 70 LGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-VLRQFS 128
Query: 477 GTFTPSIVEG---YQEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTLEAICQTAFGFP 647
+ G +E + L+ L+ +T EPFD L+ + IC FG
Sbjct: 129 IQILRNFGMGKRSIEERILEEGSFLLAELR-KTEGEPFDPTFVLSRSVSNIICSVLFGSR 187
Query: 648 KIFREHRN*RILR 686
+ + R I+R
Sbjct: 188 FDYDDERLLTIIR 200
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 31.9 bits (69), Expect = 2.3
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 177 LPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC-DTTEMPFVFWLGPRPILFISDPEDV 353
+P LPLLGN+ ++ Q L K C + + G P+L I+DP+ +
Sbjct: 38 IPGPTPLPLLGNV-------LSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 354 KGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFA 524
+ V + + S V ++ + + +A E WK LS TFT ++ + A
Sbjct: 91 RTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIA 150
Query: 525 GRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
LV+ L+ + +P + +++ I T+FG
Sbjct: 151 QYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFG 190
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 31.9 bits (69), Expect = 2.3
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ +
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLC--- 79
Query: 348 DVKGVNNAFIEKPHYYS 398
V+ + A ++K +S
Sbjct: 80 GVEAIREALVDKAEAFS 96
>BC139728-1|AAI39729.1| 250|Homo sapiens C10orf27 protein protein.
Length = 250
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 518 LRRARSRPRPETEGSYYGGALRHHARPGLHY 610
+RRA P+P+T G+Y G L HH+ H+
Sbjct: 52 IRRALRTPKPQTPGTYCFGRLSHHSFFSRHH 82
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 31.9 bits (69), Expect = 2.3
Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +3
Query: 309 LGPRPILFISDPEDVKGV----NNAFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLS 476
LGPR ++ +S + VK F + Y +F GNG+ + + WK +++ S
Sbjct: 70 LGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-VLRQFS 128
Query: 477 GTFTPSIVEG---YQEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTLEAICQTAFGFP 647
+ G +E + L+ L+ +T EPFD L+ + IC FG
Sbjct: 129 IQILRNFGMGKRSIEERILEEGSFLLAELR-KTEGEPFDPTFVLSRSVSNIICSVLFGSR 187
Query: 648 KIFREHRN*RILR 686
+ + R I+R
Sbjct: 188 FDYDDERLLTIIR 200
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 31.9 bits (69), Expect = 2.3
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ +
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLC--- 79
Query: 348 DVKGVNNAFIEKPHYYS 398
V+ + A ++K +S
Sbjct: 80 GVEAIREALVDKAEAFS 96
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 31.9 bits (69), Expect = 2.3
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 177 LPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC-DTTEMPFVFWLGPRPILFISDPEDV 353
+P LPLLGN+ ++ Q L K C + + G P+L I+DP+ +
Sbjct: 38 IPGPTPLPLLGNV-------LSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 354 KGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFA 524
+ V + + S V ++ + + +A E WK LS TFT ++ + A
Sbjct: 91 RTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIA 150
Query: 525 GRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
LV+ L+ + +P + +++ I T+FG
Sbjct: 151 QYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFG 190
>AL358817-2|CAI13855.1| 351|Homo sapiens chromosome 10 open reading
frame 27 protein.
Length = 351
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 518 LRRARSRPRPETEGSYYGGALRHHARPGLHY 610
+RRA P+P+T G+Y G L HH+ H+
Sbjct: 52 IRRALRTPKPQTPGTYCFGRLSHHSFFSRHH 82
>AK057382-1|BAB71459.1| 351|Homo sapiens protein ( Homo sapiens
cDNA FLJ32820 fis, clone TESTI2002965. ).
Length = 351
Score = 31.9 bits (69), Expect = 2.3
Identities = 13/31 (41%), Positives = 19/31 (61%)
Frame = +2
Query: 518 LRRARSRPRPETEGSYYGGALRHHARPGLHY 610
+RRA P+P+T G+Y G L HH+ H+
Sbjct: 52 IRRALRTPKPQTPGTYCFGRLSHHSFFSRHH 82
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.3
Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +3
Query: 309 LGPRPILFISDPEDVKGV----NNAFIEKPHYYSFAKVWLGNGLVVAPPEIWKNSIKKLS 476
LGPR ++ +S + VK F + Y +F GNG+ + + WK +++ S
Sbjct: 70 LGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWK-VLRQFS 128
Query: 477 GTFTPSIVEG---YQEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTLEAICQTAFGFP 647
+ G +E + L+ L+ +T EPFD L+ + IC FG
Sbjct: 129 IQILRNFGMGKRSIEERILEEGSFLLAELR-KTEGEPFDPTFVLSRSVSNIICSVLFGSR 187
Query: 648 KIFREHRN*RILR 686
+ + R I+R
Sbjct: 188 FDYDDERLLTIIR 200
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 31.9 bits (69), Expect = 2.3
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ +
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLC--- 79
Query: 348 DVKGVNNAFIEKPHYYS 398
V+ + A ++K +S
Sbjct: 80 GVEAIREALVDKAEAFS 96
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 31.9 bits (69), Expect = 2.3
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Frame = +3
Query: 177 LPSFPQ-LPLLGNIHQIPRNSI--NLFQFLEKIAVTCDTTEMPFVFWLGPRPILFISDPE 347
LP P+ LPLLGN+ Q+ R + + +F EK F LGPRP++ +
Sbjct: 30 LPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV-------FTVHLGPRPVVMLC--- 79
Query: 348 DVKGVNNAFIEKPHYYS 398
V+ + A ++K +S
Sbjct: 80 GVEAIREALVDKAEAFS 96
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 31.9 bits (69), Expect = 2.3
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 177 LPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC-DTTEMPFVFWLGPRPILFISDPEDV 353
+P LPLLGN+ ++ Q L K C + + G P+L I+DP+ +
Sbjct: 38 IPGPTPLPLLGNV-------LSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 354 KGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFA 524
+ V + + S V ++ + + +A E WK LS TFT ++ + A
Sbjct: 91 RTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIA 150
Query: 525 GRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
LV+ L+ + +P + +++ I T+FG
Sbjct: 151 QYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFG 190
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 31.5 bits (68), Expect = 3.0
Identities = 25/114 (21%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Frame = +3
Query: 306 WLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGLVVAPPEIWKNSIKKLSG 479
W+GP + F I DP+ VK + K + + W+G GLV WK + +
Sbjct: 83 WVGPFTMFFNIHDPDYVKILLKRQNPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKP 142
Query: 480 TFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP-FDIMHDLAYTTLEAICQTAF 638
F SI++ + + + ++ + + ++ ++ TL +I + AF
Sbjct: 143 GFNISILKIFITMMSKSVRMMLNKWEEHIAHNSRLELFQHVSLMTLHSIMKCAF 196
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 31.5 bits (68), Expect = 3.0
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 177 LPSFPQLPLLGNIHQIPRNSINLFQFLEKIAVTC-DTTEMPFVFWLGPRPILFISDPEDV 353
+P LPLLGN+ ++ Q L K C + + G P+L I+DP+ +
Sbjct: 38 IPGPTPLPLLGNV-------LSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 354 KGV--NNAFIEKPHYYSFAKV-WLGNGLVVAPPEIWKNSIKKLSGTFTPSIVEGYQEVFA 524
+ V + + S V ++ + + +A E WK LS TFT ++ + A
Sbjct: 91 RTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIA 150
Query: 525 GRAADLVQRLKARTTE-EPFDIMHDLAYTTLEAICQTAFG 641
LV+ L+ + +P + +++ I T+FG
Sbjct: 151 QYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFG 190
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 31.1 bits (67), Expect = 4.0
Identities = 23/114 (20%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Frame = +3
Query: 306 WLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGLVVAPPEIWKNSIKKLSG 479
W+GP + F + DP+ K + K + + W+G GLV WK + +
Sbjct: 83 WVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKP 142
Query: 480 TFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP-FDIMHDLAYTTLEAICQTAF 638
F SI++ + + + ++ + + + ++ ++ TL++I + AF
Sbjct: 143 GFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAF 196
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 31.1 bits (67), Expect = 4.0
Identities = 23/114 (20%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Frame = +3
Query: 306 WLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGLVVAPPEIWKNSIKKLSG 479
W+GP + F + DP+ K + K + + W+G GLV WK + +
Sbjct: 83 WVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKP 142
Query: 480 TFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP-FDIMHDLAYTTLEAICQTAF 638
F SI++ + + + ++ + + + ++ ++ TL++I + AF
Sbjct: 143 GFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAF 196
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 31.1 bits (67), Expect = 4.0
Identities = 23/114 (20%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Frame = +3
Query: 306 WLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGLVVAPPEIWKNSIKKLSG 479
W+GP + F + DP+ K + K + + W+G GLV WK + +
Sbjct: 83 WVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKP 142
Query: 480 TFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP-FDIMHDLAYTTLEAICQTAF 638
F SI++ + + + ++ + + + ++ ++ TL++I + AF
Sbjct: 143 GFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAF 196
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 31.1 bits (67), Expect = 4.0
Identities = 23/114 (20%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Frame = +3
Query: 306 WLGPRPILF-ISDPEDVKGVNNAFIEKPHY-YSFAKVWLGNGLVVAPPEIWKNSIKKLSG 479
W+GP + F + DP+ K + K + + W+G GLV WK + +
Sbjct: 83 WVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQIVKP 142
Query: 480 TFTPSIVEGYQEVFAGRAADLVQRLKARTTEEP-FDIMHDLAYTTLEAICQTAF 638
F SI++ + + + ++ + + + ++ ++ TL++I + AF
Sbjct: 143 GFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAF 196
>BC127112-1|AAI27113.1| 1485|Homo sapiens aquarius homolog (mouse)
protein.
Length = 1485
Score = 30.7 bits (66), Expect = 5.3
Identities = 21/71 (29%), Positives = 33/71 (46%)
Frame = -3
Query: 563 TSLQSLDEVGCAPCEDFLVSFHYTRRECARQLLDAIFPNFRWSHYQTVSKPDLRETIVMW 384
T + D+ G A E+ + + HY R ++ A FP V++ D RE++V
Sbjct: 309 TGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVK- 367
Query: 383 FFYERVVHTLH 351
FF +TLH
Sbjct: 368 FFGPLSSNTLH 378
>BC127111-1|AAI27112.1| 1485|Homo sapiens aquarius homolog (mouse)
protein.
Length = 1485
Score = 30.7 bits (66), Expect = 5.3
Identities = 21/71 (29%), Positives = 33/71 (46%)
Frame = -3
Query: 563 TSLQSLDEVGCAPCEDFLVSFHYTRRECARQLLDAIFPNFRWSHYQTVSKPDLRETIVMW 384
T + D+ G A E+ + + HY R ++ A FP V++ D RE++V
Sbjct: 309 TGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVK- 367
Query: 383 FFYERVVHTLH 351
FF +TLH
Sbjct: 368 FFGPLSSNTLH 378
>AB011132-1|BAA25486.3| 1521|Homo sapiens KIAA0560 protein protein.
Length = 1521
Score = 30.7 bits (66), Expect = 5.3
Identities = 21/71 (29%), Positives = 33/71 (46%)
Frame = -3
Query: 563 TSLQSLDEVGCAPCEDFLVSFHYTRRECARQLLDAIFPNFRWSHYQTVSKPDLRETIVMW 384
T + D+ G A E+ + + HY R ++ A FP V++ D RE++V
Sbjct: 345 TGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVK- 403
Query: 383 FFYERVVHTLH 351
FF +TLH
Sbjct: 404 FFGPLSSNTLH 414
>BC038808-1|AAH38808.1| 373|Homo sapiens apolipoprotein B mRNA
editing enzyme, catalytic polypeptide-like 3F protein.
Length = 373
Score = 30.3 bits (65), Expect = 7.0
Identities = 16/60 (26%), Positives = 28/60 (46%)
Frame = -3
Query: 521 EDFLVSFHYTRRECARQLLDAIFPNFRWSHYQTVSKPDLRETIVMWFFYERVVHTLHILW 342
+D H T +E R ++A++P+ + H++ + K R + F E V H I W
Sbjct: 174 DDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPISW 233
>X98330-1|CAA66975.1| 4967|Homo sapiens ryanodine receptor 2 protein.
Length = 4967
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3221 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3278
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3279 NILKIIYNNLGIDEGAWMKRLAV 3301
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 29.9 bits (64), Expect = 9.3
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Frame = +3
Query: 309 LGPRPILFISDPEDVKGV----NNAFIEKPHYYSFAKVWLGNGLVVAPPEIWKN----SI 464
LGPR ++ +S + VK F + Y +F GNG+ + + WK SI
Sbjct: 70 LGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSI 129
Query: 465 KKLS--GTFTPSIVEGYQEVFAGRAADLVQRLKARTTEEPFDIMHDLAYTTLEAICQTAF 638
+ L G SI E E + AD+ +T EPFD L+ + IC F
Sbjct: 130 QILRNFGMGKRSIEERILEEGSFLLADV-----RKTEGEPFDPTFVLSRSVSNIICSVLF 184
Query: 639 GFPKIFREHRN*RILR 686
G + + R I+R
Sbjct: 185 GSRFDYDDERLLTIIR 200
>DQ146365-1|AAZ38720.1| 373|Homo sapiens apolipoprotein B mRNA
editing enzyme, catalytic polypeptide-like 3F protein.
Length = 373
Score = 29.9 bits (64), Expect = 9.3
Identities = 15/60 (25%), Positives = 28/60 (46%)
Frame = -3
Query: 521 EDFLVSFHYTRRECARQLLDAIFPNFRWSHYQTVSKPDLRETIVMWFFYERVVHTLHILW 342
+D H T +E R ++A++P+ + H++ + K R + F E V H + W
Sbjct: 174 DDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSW 233
>BC016559-1|AAH16559.1| 587|Homo sapiens SAC1 suppressor of actin
mutations 1-like (yeast) protein.
Length = 587
Score = 29.9 bits (64), Expect = 9.3
Identities = 15/43 (34%), Positives = 26/43 (60%)
Frame = -3
Query: 671 VTMLSEYLRKTEGCLTYSLKRSVGQVVHDVEGLLRSTSLQSLD 543
+++L + + + + L+Y L S GQVV + EG+ RS + LD
Sbjct: 352 LSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLD 394
>AL513130-1|CAI15936.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AL445473-1|CAH71393.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AL442065-1|CAI15350.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AL391809-1|CAI14440.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AL365332-1|CAH71369.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AL359924-1|CAI22065.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AL356773-1|CAH73918.1| 4965|Homo sapiens ryanodine receptor 2
(cardiac) protein.
Length = 4965
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3219 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3276
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3277 NILKIIYNNLGIDEGAWMKRLAV 3299
>AJ300340-1|CAC18855.1| 4967|Homo sapiens ryanodine receptor 2
protein.
Length = 4967
Score = 29.9 bits (64), Expect = 9.3
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Frame = +3
Query: 45 LCSSGFRILSMLIMSEVLWCLLMLCACV--WWWCSA---PRRTRKLLAALPSFPQLPLLG 209
L SG R M + EV+ L MLC+ + WW P R AL S LLG
Sbjct: 3221 LAESGIRYTQMPHVMEVI--LPMLCSYMSRWWEHGPENNPERAEMCCTALNSEHMNTLLG 3278
Query: 210 NIHQIPRNSINLFQ--FLEKIAV 272
NI +I N++ + + +++++AV
Sbjct: 3279 NILKIIYNNLGIDEGAWMKRLAV 3301
>AJ297357-2|CAB95945.1| 542|Homo sapiens KIAA0851 protein protein.
Length = 542
Score = 29.9 bits (64), Expect = 9.3
Identities = 15/43 (34%), Positives = 26/43 (60%)
Frame = -3
Query: 671 VTMLSEYLRKTEGCLTYSLKRSVGQVVHDVEGLLRSTSLQSLD 543
+++L + + + + L+Y L S GQVV + EG+ RS + LD
Sbjct: 352 LSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLD 394
>AJ289880-1|CAB96871.1| 426|Homo sapiens KIAA0851 protein protein.
Length = 426
Score = 29.9 bits (64), Expect = 9.3
Identities = 15/43 (34%), Positives = 26/43 (60%)
Frame = -3
Query: 671 VTMLSEYLRKTEGCLTYSLKRSVGQVVHDVEGLLRSTSLQSLD 543
+++L + + + + L+Y L S GQVV + EG+ RS + LD
Sbjct: 191 LSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLD 233
>AB020658-1|BAA74874.2| 607|Homo sapiens KIAA0851 protein protein.
Length = 607
Score = 29.9 bits (64), Expect = 9.3
Identities = 15/43 (34%), Positives = 26/43 (60%)
Frame = -3
Query: 671 VTMLSEYLRKTEGCLTYSLKRSVGQVVHDVEGLLRSTSLQSLD 543
+++L + + + + L+Y L S GQVV + EG+ RS + LD
Sbjct: 372 LSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLD 414
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,204,599
Number of Sequences: 237096
Number of extensions: 2314105
Number of successful extensions: 5747
Number of sequences better than 10.0: 145
Number of HSP's better than 10.0 without gapping: 5390
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5720
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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