Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0425
(755 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 298 1e-79
UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 280 3e-74
UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 277 3e-73
UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 248 1e-64
UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 237 2e-61
UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 235 1e-60
UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 230 3e-59
UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 215 1e-54
UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 210 3e-53
UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 209 5e-53
UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 207 2e-52
UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 201 1e-50
UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 196 4e-49
UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 171 2e-41
UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 165 1e-39
UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 160 4e-38
UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 154 2e-36
UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 148 1e-34
UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 135 1e-30
UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 128 2e-28
UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 124 2e-27
UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 124 3e-27
UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 121 2e-26
UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 121 2e-26
UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 118 2e-25
UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 116 5e-25
UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 116 6e-25
UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 115 1e-24
UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 114 2e-24
UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 114 3e-24
UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 114 3e-24
UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 113 6e-24
UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 112 8e-24
UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 112 8e-24
UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 112 1e-23
UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 111 2e-23
UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 111 2e-23
UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 111 2e-23
UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 110 3e-23
UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 110 4e-23
UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 110 4e-23
UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 109 5e-23
UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 108 1e-22
UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 108 2e-22
UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 107 2e-22
UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 107 3e-22
UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 107 3e-22
UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 107 3e-22
UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 107 3e-22
UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 107 4e-22
UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 106 5e-22
UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 106 7e-22
UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 105 1e-21
UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 105 1e-21
UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 103 4e-21
UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 103 4e-21
UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 103 5e-21
UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 102 8e-21
UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 102 1e-20
UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 101 1e-20
UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 101 2e-20
UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 100 3e-20
UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 99 1e-19
UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 98 2e-19
UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 98 2e-19
UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 98 2e-19
UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 97 3e-19
UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 97 3e-19
UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 97 4e-19
UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 77 5e-19
UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 96 1e-18
UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 95 2e-18
UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intes... 94 4e-18
UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 94 4e-18
UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 93 5e-18
UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 92 1e-17
UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 92 1e-17
UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 92 1e-17
UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 90 5e-17
UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 89 8e-17
UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 89 8e-17
UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 89 1e-16
UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 88 2e-16
UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 88 3e-16
UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Tri... 84 3e-15
UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 80 5e-14
UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 80 7e-14
UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 79 1e-13
UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; T... 79 2e-13
UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vit... 78 2e-13
UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 78 3e-13
UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 76 1e-12
UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 75 1e-12
UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome... 75 2e-12
UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 75 3e-12
UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 73 8e-12
UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 73 8e-12
UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 73 8e-12
UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 73 1e-11
UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 73 1e-11
UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 70 5e-11
UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 69 9e-11
UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermopro... 69 1e-10
UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;... 69 2e-10
UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 68 2e-10
UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillard... 67 4e-10
UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; ... 67 5e-10
UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1; ... 66 7e-10
UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5; Thermopr... 66 1e-09
UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 62 1e-08
UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 61 3e-08
UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9;... 61 3e-08
UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1; ... 60 6e-08
UniRef50_Q9P996 Cluster: Proteasome subunit beta precursor; n=10... 59 1e-07
UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 58 2e-07
UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 58 3e-07
UniRef50_Q980L4 Cluster: Proteasome subunit; n=4; Sulfolobaceae|... 56 7e-07
UniRef50_Q9NC68 Cluster: 20S proteasome alpha subunit; n=1; Spra... 56 9e-07
UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia... 55 2e-06
UniRef50_A5UM14 Cluster: Proteasome, beta subunit; n=1; Methanob... 55 2e-06
UniRef50_Q4UIA0 Cluster: Proteasome subunit beta type; n=8; Acon... 53 7e-06
UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encep... 52 1e-05
UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfuro... 52 2e-05
UniRef50_Q8SQS5 Cluster: 20S PROTEASOME ALPHA SUBUNIT; n=1; Ence... 48 2e-04
UniRef50_Q9V247 Cluster: PsmB proteasome, subunit beta; n=4; The... 48 2e-04
UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04
UniRef50_Q9HR36 Cluster: Proteasome, subunit alpha; n=7; Halobac... 48 3e-04
UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia t... 46 0.001
UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;... 46 0.001
UniRef50_Q5B7I7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_A7DSL9 Cluster: Proteasome endopeptidase complex; n=1; ... 43 0.009
UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar... 42 0.012
UniRef50_Q8LD27 Cluster: Proteasome subunit beta type-6 precurso... 40 0.050
UniRef50_O23370 Cluster: Cell wall protein like; n=15; Magnoliop... 40 0.066
UniRef50_Q22X00 Cluster: Proteasome A-type and B-type family pro... 40 0.066
UniRef50_Q98S31 Cluster: Proteasome subunit beta type; n=1; Guil... 40 0.088
UniRef50_Q8SQN7 Cluster: Proteasome subunit beta type; n=1; Ence... 39 0.15
UniRef50_Q1ZXN1 Cluster: Proteasome subunit beta type; n=2; Dict... 37 0.47
UniRef50_A2F716 Cluster: Proteasome subunit beta type; n=1; Tric... 37 0.47
UniRef50_A2E7Z2 Cluster: Proteasome subunit beta type; n=1; Tric... 37 0.47
UniRef50_A6R393 Cluster: Proteasome component C5; n=5; Ascomycot... 37 0.62
UniRef50_Q74MP5 Cluster: NEQ203; n=1; Nanoarchaeum equitans|Rep:... 37 0.62
UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82
UniRef50_Q0AUA9 Cluster: Peptidase M23B precursor; n=1; Syntroph... 36 0.82
UniRef50_Q23FB2 Cluster: Proteasome, putative; n=5; Oligohymenop... 36 0.82
UniRef50_Q7DLS1 Cluster: Proteasome subunit beta type-7-B precur... 36 1.1
UniRef50_P49721 Cluster: Proteasome subunit beta type-2; n=40; F... 36 1.1
UniRef50_A0RU86 Cluster: 20S proteasome, alpha and beta subunit;... 35 1.9
UniRef50_P25043 Cluster: Proteasome component PUP1 precursor; n=... 35 2.5
UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giar... 34 3.3
UniRef50_Q9N9W8 Cluster: Proteasome subunit beta type-3; n=2; Gi... 34 3.3
UniRef50_P23724 Cluster: Proteasome component C5; n=23; Fungi/Me... 34 4.4
UniRef50_UPI0000499AD3 Cluster: kinesin family protein; n=1; Ent... 26 4.7
UniRef50_UPI0000E81D63 Cluster: PREDICTED: similar to RP5-1022P6... 33 7.6
UniRef50_Q62B05 Cluster: Type III secretion system protein BsaZ;... 33 7.6
UniRef50_Q3VNT6 Cluster: Putative uncharacterized protein; n=1; ... 33 7.6
UniRef50_Q5C084 Cluster: SJCHGC07669 protein; n=1; Schistosoma j... 33 7.6
UniRef50_Q5ADT0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.6
UniRef50_A0B983 Cluster: SMC domain protein; n=1; Methanosaeta t... 33 7.6
>UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1;
Anopheles gambiae str. PEST|Rep: Proteasome subunit
alpha type - Anopheles gambiae str. PEST
Length = 278
Score = 298 bits (731), Expect = 1e-79
Identities = 151/254 (59%), Positives = 184/254 (72%), Gaps = 25/254 (9%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYAAKAVENSGTVIGLRGKDGVV AVEKLITSKLYEP RIF ID +GMA++G+I
Sbjct: 23 QIEYAAKAVENSGTVIGLRGKDGVVLAVEKLITSKLYEPDCGTRIFTIDTSIGMAISGMI 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D R +V+ AR EA++YR Q P+PLK LN+R+S Y HAYTLYSAVRP+G SV++ +W+
Sbjct: 83 TDGRAVVDIARQEAASYRQQNNRPIPLKQLNDRLSSYFHAYTLYSAVRPFGVSVILASWS 142
Query: 394 DYEGPQMYMLDPSGVSF-------------------------SYFGCAVGKAKQAAKTEI 290
+ +GP+MYM+DPSGVS YFGCAVGKAKQ AKTEI
Sbjct: 143 EEKGPEMYMIDPSGVSCVSLSQKQTGESSTTLATIVMYYYFQGYFGCAVGKAKQTAKTEI 202
Query: 289 EKLKLGDLTVKELVREAARIIYLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAE 110
EKLKL D++VK+LV A +IIY VHDELKDK F+LELSWV +D+ G H+ VP E+ A
Sbjct: 203 EKLKLSDMSVKDLVLTAGKIIYQVHDELKDKDFKLELSWVCQDSNGIHKTVPAEVYA-AA 261
Query: 109 NQAKQALADIEDSD 68
N+A Q D +DSD
Sbjct: 262 NRAGQEAVDEDDSD 275
>UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12;
Magnoliophyta|Rep: Proteasome subunit alpha type-3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 249
Score = 280 bits (686), Expect = 3e-74
Identities = 129/226 (57%), Positives = 173/226 (76%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYAAKAV+NSGTV+G++ KDG+V VEKLI SK+ PG+N+RI + H GMAVAGL
Sbjct: 23 QIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRRIHSVHRHAGMAVAGLA 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D RQIV A+SEA +Y S YG VP+K L+ERV+ Y+H TLY +RP+GC V++G +
Sbjct: 83 ADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLYWWLRPFGCGVILGGY- 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D +GPQ+YM++PSG+S+ YFG A+GK KQAAKTEIEKL L ++T KE V E A+IIY +H
Sbjct: 142 DRDGPQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEKLNLSEMTCKEGVIEVAKIIYKLH 201
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIE 77
DE KDK FELE+SW+ +++K H+ VP +L EA+ AK AL +++
Sbjct: 202 DEAKDKAFELEMSWICEESKREHQKVPDDLLEEAKTAAKTALEEMD 247
>UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11;
Eukaryota|Rep: Proteasome subunit alpha type-3 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 277 bits (678), Expect = 3e-73
Identities = 119/224 (53%), Positives = 171/224 (76%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QV+YA KAVENSGT++ ++ KDGVV VEKL+ SK+ G+N+R+ HID HVG+A+AG +
Sbjct: 23 QVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLCSGSNRRVHHIDTHVGVAIAGFL 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DARQ++ ARSEA NY+S YG P+P+K L++R++ Y H +TLY +VRP+GCS+ + T
Sbjct: 83 ADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYNHMHTLYGSVRPFGCSIAI-TGI 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D GPQ+++++PSG YFG ++GK KQAAK E+E+++ ++T +E ++E +RIIY VH
Sbjct: 142 DQYGPQLFLVEPSGSCVGYFGASLGKGKQAAKNELEEIRFSEMTCREAIKEVSRIIYSVH 201
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALAD 83
DE+KDK FELEL W+S +T H++VP+EL E E AKQ+L D
Sbjct: 202 DEVKDKDFELELGWISTETDNVHQIVPKELHDEGEAYAKQSLED 245
>UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA,
RIKEN full-length enriched library, clone:C920013M15
product:proteasome (prosome, macropain) subunit, alpha
type 3, full insert sequence; n=13; Euteleostomi|Rep: 2
days neonate thymus thymic cells cDNA, RIKEN full-length
enriched library, clone:C920013M15 product:proteasome
(prosome, macropain) subunit, alpha type 3, full insert
sequence - Mus musculus (Mouse)
Length = 180
Score = 248 bits (607), Expect = 1e-64
Identities = 107/180 (59%), Positives = 152/180 (84%)
Frame = -2
Query: 595 MAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS 416
MAVAGL++DAR + + AR EASN+RS +G +PLK+L +RV+MY+HAYTLYSAVRP+GCS
Sbjct: 1 MAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCS 60
Query: 415 VVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAA 236
++G+++ +G Q+YM+DPSGVS+ Y+GCA+GKA+QAAKTEIEKL++ ++T +++V+E A
Sbjct: 61 FMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVA 120
Query: 235 RIIYLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSDEGEM 56
+IIY+VHDE+KDK FELELSWV + TKGRHE+VP+++ EAE AK+ L + ++SD+ M
Sbjct: 121 KIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKEFLKEEDESDDDNM 180
>UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Aspergillus terreus (strain NIH 2624)
Length = 311
Score = 237 bits (581), Expect = 2e-61
Identities = 136/279 (48%), Positives = 175/279 (62%), Gaps = 48/279 (17%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAVEN GT IG+R KDGVV AVEK+ITSKL +PGANKRI +D HVG+ +GL+
Sbjct: 23 QVEYAVKAVENGGTAIGIRCKDGVVLAVEKIITSKLLKPGANKRIATVDRHVGIVSSGLV 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R V AR EAS++R Y SP+P+ L+ R+ Y+ AYTLYS+VRP+G + ++G W
Sbjct: 83 PDGRHFVSRARDEASSWRGVYKSPIPVSALSNRLGSYVQAYTLYSSVRPFGITAIIGGWD 142
Query: 394 D---------------------YEG-----PQMYMLDPSGVSF----------------S 341
EG P +YM++PSG+ +
Sbjct: 143 SEAELAVDGQVGSGPTSGAGGKVEGAKSGGPGLYMIEPSGLYWVGDVPSRVWAHAYGFQG 202
Query: 340 YFGCAVGKAKQAAKTEIEKLKL--GDLTVKELVREAARIIYLVHDELKDKQFELELSWVS 167
Y+G A GK +QAAK E+EKL L G L++ E V+EAARIIY+ H++ KDK+FELE+SW+S
Sbjct: 203 YYGAATGKGRQAAKAELEKLDLASGSLSLTEGVKEAARIIYVAHEDSKDKEFELEMSWIS 262
Query: 166 K---DTKGRHELVPRELATEAENQAKQAL-ADIEDSDEG 62
TKGRHE VP+EL EAE AK++L D ED DEG
Sbjct: 263 SLDGPTKGRHEEVPKELLEEAEKAAKKSLEGDDEDDDEG 301
>UniRef50_A6R382 Cluster: Proteasome component C1; n=3;
Pezizomycotina|Rep: Proteasome component C1 -
Ajellomyces capsulatus NAm1
Length = 426
Score = 235 bits (574), Expect = 1e-60
Identities = 127/263 (48%), Positives = 167/263 (63%), Gaps = 31/263 (11%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAVEN GT IG+R KDGVV AVEK+I+SKL +PGANKRI +D H+G+ +GL+
Sbjct: 152 QVEYAVKAVENGGTSIGIRCKDGVVLAVEKIISSKLLKPGANKRIATVDRHIGIVSSGLL 211
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW- 398
D R V AR EA N+R Y P+ L R+ Y AYTLYS+VRP+G + ++G W
Sbjct: 212 PDGRHFVSRARDEADNWRITYKGPISTHVLASRLGGYAQAYTLYSSVRPFGVTSIIGGWD 271
Query: 397 ------TDYE-------------------GPQMYMLDPSGVSFSYFGCAVGKAKQAAKTE 293
D E GP +YM++PSG+ + Y+G A GK +QAAK E
Sbjct: 272 SELELPVDGEVGAGPKSGAGGKVASAKAGGPGLYMIEPSGLYWGYYGAATGKGRQAAKAE 331
Query: 292 IEKLKL--GDLTVKELVREAARIIYLVHDELKDKQFELELSWVSK---DTKGRHELVPRE 128
+EKL L G+ T+ + V+EAARIIY+ H++ KDK FELE++W+S TKGRHE VP+
Sbjct: 332 LEKLDLASGNFTLLQGVKEAARIIYVAHEDSKDKDFELEMTWISAMDGPTKGRHEEVPKA 391
Query: 127 LATEAENQAKQALADIEDSDEGE 59
L EA +AKQA+ ++ DE E
Sbjct: 392 LLEEAIREAKQAMEGDDEDDEEE 414
>UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8;
Eukaryota|Rep: Proteasome subunit alpha type -
Alexandrium fundyense (Dinoflagellate)
Length = 254
Score = 230 bits (562), Expect = 3e-59
Identities = 113/233 (48%), Positives = 155/233 (66%), Gaps = 4/233 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAVENSGT + + KDGV+FAVEK + SK+ G NKRIF + H GM++AG
Sbjct: 23 QVEYAQKAVENSGTTVAICCKDGVIFAVEKFLLSKMLVQGTNKRIFPVHRHAGMSIAGFS 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMG-TW 398
+D+RQIV ARSEA Y++ Y +P + L ER+ +++HAYTLY ++RP+GCSV++G
Sbjct: 83 ADSRQIVARARSEAHQYKNSYNEEIPPELLAERLGLFVHAYTLYWSIRPFGCSVLLGCVD 142
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLG---DLTVKELVREAARII 227
D + P ++ +DP+G+ F Y G A+GK KQAAKTEIEKL LT E + A+I+
Sbjct: 143 QDTKKPSLFCVDPAGMVFKYSGTAIGKGKQAAKTEIEKLLANGTESLTCAEALVHVAKIL 202
Query: 226 YLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSD 68
+ VHDE KDK FELE SW+ + H +VP ++ AE +AK+ + E D
Sbjct: 203 HKVHDE-KDKDFELEASWICPASNYEHAVVPSDMLKAAETEAKRLIEAEEQED 254
>UniRef50_P21242 Cluster: Proteasome component C1; n=18;
Eukaryota|Rep: Proteasome component C1 - Saccharomyces
cerevisiae (Baker's yeast)
Length = 288
Score = 215 bits (525), Expect = 1e-54
Identities = 108/236 (45%), Positives = 154/236 (65%), Gaps = 4/236 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAVEN T IG++ DGVVFAVEKLITSKL P N +I +D H+G +GLI
Sbjct: 23 QVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKIQVVDRHIGCVYSGLI 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R +V R EA++++ Y +P+P+ +R+ Y+ A+TLY++VRP+G S + G
Sbjct: 83 PDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFG-GV 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKL---KLGDLTVKELVREAARIIY 224
D G +YML+PSG + Y G A GK +Q+AK E+EKL L+ +E V++AA+IIY
Sbjct: 142 DKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIY 201
Query: 223 LVHDELKDKQFELELSWVS-KDTKGRHELVPRELATEAENQAKQALADIEDSDEGE 59
L H++ K+K FELE+SW S +T G H+ V +L EA + A++ + +D DE +
Sbjct: 202 LAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQKEINGDDDEDEDD 257
>UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 210 bits (513), Expect = 3e-53
Identities = 92/229 (40%), Positives = 149/229 (65%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAVENS TVIG++ KDGV+ A EK S+L E NKRI++ID GMA+ G +
Sbjct: 21 QVEYATKAVENSETVIGVKCKDGVILAGEKQKFSRLLEDNTNKRIYNIDTQTGMAICGKL 80
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R I++ A++E+S Y+ Y PV L++RV+ Y+HAYT+YS RP+G + + ++
Sbjct: 81 PDGRNILQRAKAESSQYQDMYAIPVSANVLSDRVAQYVHAYTMYSGARPFGSATFIASYN 140
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
++G +++M++PSG ++Y C GK + K+E E+ DLT +E + A+++ L H
Sbjct: 141 TFDGYELFMIEPSGNKYAYHACTHGKGRAVCKSEFERRNFKDLTCQEALVYIAKMLILAH 200
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSD 68
+E K+K++E E++W++ + +H+ VP++L A QA+Q + + D
Sbjct: 201 EEFKEKKYEYEMTWITDNNGRKHQSVPQDLINNAVQQAEQLIEQDQMGD 249
>UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2;
Caenorhabditis|Rep: Proteasome subunit alpha type-3 -
Caenorhabditis elegans
Length = 250
Score = 209 bits (511), Expect = 5e-53
Identities = 103/230 (44%), Positives = 152/230 (66%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAV+N+GT+I +RGK+GVV +KLI+SKLY AN R+F+++++VG+AVAG
Sbjct: 23 QVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYTDNANPRMFNVNDNVGVAVAGNY 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D + A EA + Y P+P++ + V+ Y+H +TL RP+G +W
Sbjct: 83 PDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYIHIHTL-GISRPFGAGAFFMSWN 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
G ++++++PSG+++ Y AVGK +QAAK EIEKLK+ +L V +LV+EAARII +V
Sbjct: 142 KQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEKLKIEELDVNQLVKEAARIIMVVR 201
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSDE 65
DE KDK ++E+ WV + T G++E VP E+ T AE A L D +D D+
Sbjct: 202 DENKDKNVQIEMGWVGEQTNGKYEEVPSEVVTAAEEWAIAKL-DEDDMDD 250
>UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 247
Score = 207 bits (506), Expect = 2e-52
Identities = 93/219 (42%), Positives = 145/219 (66%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q++YA KAVENS T + ++ DGVVF VEKLI SK+ E +NKRIF++ HVG+ AG +
Sbjct: 23 QIDYATKAVENSATALSIKCIDGVVFGVEKLIISKMIEKSSNKRIFNVGTHVGITCAGFL 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
DAR++V+ A EA +++ YG +P+K L E+++MYM +TLY ++RP+GCS+++G
Sbjct: 83 PDARKLVKKANEEAESFKENYGMNIPVKVLAEKIAMYMQNHTLYGSLRPFGCSLLIG-GV 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D G ++ ++PSG ++ YF +GK KQ K E+EK+ +T +E + + II L H
Sbjct: 142 DQHGYSLHYIEPSGTTYGYFANGIGKGKQICKNELEKINFSQITCEEALVKLVEIIDLCH 201
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAK 98
E KDK +E+ELSW+S+ T + V +E+ + +Q +
Sbjct: 202 GEWKDKPYEIELSWISEKTNNIVKKVDKEMKQKIIDQVR 240
>UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 251
Score = 201 bits (491), Expect = 1e-50
Identities = 91/229 (39%), Positives = 148/229 (64%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAV+NSGT I + G+VFAV+K + SK+ G N+R+F ID +G VAG +
Sbjct: 23 QVEYANKAVDNSGTTIAMIYNSGIVFAVDKYVASKMMVAGTNRRVFAIDNQIGCCVAGFV 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D+ +IV ARSE+ NY+ YG+P+P++ L ER++MYMH +TLY +VRP+GCS+++G
Sbjct: 83 TDSNKIVSIARSESLNYQKIYGNPIPIRVLAERIAMYMHNFTLYGSVRPFGCSILLGGLD 142
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
G ++Y + PSG + Y AVGK +Q A+T++EKL +L+ ++ + EAAR+I
Sbjct: 143 QDRGVELYCIHPSGSCYKYCAMAVGKGRQFARTDLEKLMEKNLSEEDALYEAARVIIQSR 202
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSD 68
+E K ELE++++ + + +VP + + ++ + D+ ++
Sbjct: 203 EEGASKNLELEMAFIGPGSDFQFSIVPEKQINLLNERVEKYIDDLASAE 251
>UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1;
Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit -
Trypanosoma brucei
Length = 237
Score = 196 bits (479), Expect = 4e-49
Identities = 92/210 (43%), Positives = 132/210 (62%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAV+N T + KDGVV AVEK++TS++ E G+N RI +D G+ V G++
Sbjct: 21 QVEYACKAVDNGSTAVAACCKDGVVVAVEKILTSRMLEEGSNNRIHAVDRQAGICVCGVL 80
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D +V AR EA N R + +P+ L R+ +MH YT + A RP+GCSV++ ++
Sbjct: 81 PDGLAVVSRARGEAENSRDIFSTPILGSLLASRIGEFMHVYTTHYAYRPFGCSVIIASYA 140
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D +GPQ+Y+ DPSG Y+G A+GK K AKTE+EKL LT E V + I++ VH
Sbjct: 141 D-DGPQLYVADPSGAVAGYYGIALGKGKTVAKTELEKLDFATLTCSEAVEKLTNILHEVH 199
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPREL 125
D+ KDK +E+E++WV + VP+E+
Sbjct: 200 DKSKDKIYEVEVAWVCDKSDRTFVHVPKEM 229
>UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Proteasome A-type and B-type family protein -
Tetrahymena thermophila SB210
Length = 244
Score = 171 bits (416), Expect = 2e-41
Identities = 81/228 (35%), Positives = 131/228 (57%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAV +S T++G+R KDGV+ EK + +KL +++RI++I +++GM V G I
Sbjct: 17 QVEYAQKAVSDSETILGVRCKDGVILGAEKKLQTKLMVEDSDRRIYNIQKNIGMIVGGRI 76
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R +V AR EA Y + P+ + L+ER Y+HA+TLY A RP+GCSV++ ++
Sbjct: 77 PDGRNVVHRARKEAQEYEKYFSMPISGRILSERTGQYLHAHTLYGAYRPFGCSVIISSYD 136
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
+G Q++ D +G Y+ CA G+ KQ + DLT +E + +
Sbjct: 137 PIDGLQLHQSDNAGYCLGYYACAQGQGKQEVMAHFGRRNFRDLTCEEALPYVILALNKAR 196
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDS 71
E + ++ E+SW+++ H VP ++ A+ QA +A+ + EDS
Sbjct: 197 KEANEGIYQYEVSWITEKNNYVHCHVPNDIRDSAQVQA-EAMIEAEDS 243
>UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus tauri
Length = 262
Score = 165 bits (400), Expect = 1e-39
Identities = 76/171 (44%), Positives = 112/171 (65%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAV+ G +G++ DGVV A EKL+ SKL++PG N+R + H G+ +G
Sbjct: 83 QVEYAGKAVDAGGLTVGVKCVDGVVIACEKLVPSKLHKPGTNRRTRAVARHAGVGGSGYT 142
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D + + AR+E +NY+S YG +P K L ER++ Y H +TLY +VRP+GCS ++G
Sbjct: 143 PDLAAVADRARAECANYKSFYGDAIPGKVLAERMAHYYHLFTLYWSVRPFGCSTLLGC-K 201
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVRE 242
D++G +Y+++ +G G +GK K AAKTE+EKLKL ++T E V+E
Sbjct: 202 DFDGYHLYLVEQNGECAKMRGACIGKGKNAAKTEVEKLKLNEITCAEAVKE 252
>UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 240
Score = 160 bits (388), Expect = 4e-38
Identities = 79/210 (37%), Positives = 122/210 (58%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAVE +G++ KDG++ A EK +TS L PG N RIF I++ + A G
Sbjct: 23 QVEYATKAVEKDSLALGVKCKDGILLAAEKNLTSTLLTPGGNPRIFWINDSIACATIGHR 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D IVE +R+ A + S +G + + L VS H Y A RP+GC+V+ +
Sbjct: 83 PDCYSIVEQSRNRAETFTSNFGIKITVPQLASEVSQQFHLAHYYQAYRPFGCTVI---FA 139
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
Y+ +Y ++PSG + YF GK A+ E++K + ++TV+E V E ARII +H
Sbjct: 140 SYKDDALYAIEPSGAFYGYFASCFGKNSNLARAELQKTEWKNITVREAVPEVARIIKSLH 199
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPREL 125
E + K++E+E+ W+ ++T GR + VP ++
Sbjct: 200 -ESQFKKWEIEMFWLCEETNGRPQKVPEDV 228
>UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative;
n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3,
putative - Theileria parva
Length = 267
Score = 154 bits (374), Expect = 2e-36
Identities = 86/238 (36%), Positives = 139/238 (58%), Gaps = 20/238 (8%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYE-PGANK-------RIFHIDEHV 599
QVEYA KAV+++ T + DG+VFA + L + P AN R+F +DE +
Sbjct: 23 QVEYATKAVDSAPTAVAAVFSDGIVFAADSLACGAQDDSPYANVLQAKPAWRVFAVDERM 82
Query: 598 GMAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGC 419
G AVAGL+ DA+ +V A+ E ++ +YG+ P++ + ERV++++HAYTLY VRP+G
Sbjct: 83 GAAVAGLLPDAKCVVRRAQEECKSFLKEYGTKAPVRVIAERVALFVHAYTLYWHVRPFGV 142
Query: 418 SVVM-GT-----WTDYE------GPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKL 275
S+++ GT T Y ++Y ++ SG + Y G A+GK K AKTE+EKL L
Sbjct: 143 SILLAGTNENNSRTTYSVLQLFTSYELYCIEGSGACYKYGGMAIGKGKHIAKTELEKLNL 202
Query: 274 GDLTVKELVREAARIIYLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQA 101
+ KE + + II DE K +++++W+ D+ +++P+EL +A++QA
Sbjct: 203 KEKKCKESLSDICYIISQCRDEGSLKTSDVQMAWICPDSNNTFQIIPQELINDAKSQA 260
>UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative;
n=6; Plasmodium|Rep: 20S proteasome alpha subunit G,
putative - Plasmodium vivax
Length = 253
Score = 148 bits (359), Expect = 1e-34
Identities = 75/229 (32%), Positives = 131/229 (57%), Gaps = 4/229 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAV--EKLITSKLYEPGANKRIFHIDEHVGMAVAG 581
QVEY KA+ ++ T + L KDG++ L+ +K+ + + RI HI+ +V + AG
Sbjct: 23 QVEYIYKAINSNNTALSLECKDGLLTCCVNSNLLKNKMIKHSSYSRIHHINNNVIVTYAG 82
Query: 580 LISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGT 401
L DAR I++ A+ EA++Y + + +PL L RVS+Y+H++TLY +RP+ S+++ +
Sbjct: 83 LDGDARNIIDRAKYEANSYYLNFHTNIPLHILANRVSLYLHSFTLYWHLRPFASSIILAS 142
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYL 221
+ + E ++Y ++P+G + Y G +GK K+ KTEIEK D+ VKE + + +II
Sbjct: 143 FDEKEKGEIYCVEPNGACYKYSGVVIGKNKEMFKTEIEKRNYKDVDVKEALVDIYKIILT 202
Query: 220 VHDELKDKQFE--LELSWVSKDTKGRHELVPRELATEAENQAKQALADI 80
D + + SWV KD+ +++V E EA A +++ +
Sbjct: 203 SDDHMNKNNLPHLVNFSWVCKDSSYEYQVVDSETLNEAMRVAVESVEQL 251
>UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5;
Magnoliophyta|Rep: Proteasome subunit alpha type-4 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 250
Score = 135 bits (327), Expect = 1e-30
Identities = 72/196 (36%), Positives = 113/196 (57%), Gaps = 1/196 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGL 578
QVEYA +A+ N+G+ IG+ KDGVV EK +TSKL + + ++++ ID+HV AVAG+
Sbjct: 20 QVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEKMYKIDDHVACAVAGI 79
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+SDA ++ TAR +A Y Y P+P++ L + + YT + +RP+G S + W
Sbjct: 80 MSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQFGGLRPFGVSFLFAGW 139
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
+ G Q+YM DPSG + AVG QAA++ +++ D T +E V A +++
Sbjct: 140 DKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDATREEAVELALKVLTKT 199
Query: 217 HDELKDKQFELELSWV 170
D +LEL+ V
Sbjct: 200 MDSTSLTSEKLELAEV 215
>UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29;
Archaea|Rep: Proteasome subunit alpha - Methanococcus
jannaschii
Length = 261
Score = 128 bits (308), Expect = 2e-28
Identities = 74/230 (32%), Positives = 126/230 (54%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV T IG+ KDGVV AV++ ITSKL + + ++IF ID+HV A +GL+
Sbjct: 24 QVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQIDDHVAAATSGLV 83
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +++ AR EA YR YG + ++ L +++ AYT + VRP+G S+++
Sbjct: 84 ADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLI-AGI 142
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D +++ DPSG Y A+G + +EK D+T+ E + A + +
Sbjct: 143 DKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKAN 202
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSDE 65
+++K + ++ + V KD + + +P E + + K+ L + +E
Sbjct: 203 EDIKPENVDVCIITV-KD--AQFKKIPVEEIKKLIEKVKKKLNEENKKEE 249
>UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8;
Euryarchaeota|Rep: Proteasome subunit alpha -
Methanococcus maripaludis
Length = 259
Score = 124 bits (300), Expect = 2e-27
Identities = 64/192 (33%), Positives = 109/192 (56%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV T +G++ KDGVV AV++ ITSKL + + ++IF ID+H+ A +GL+
Sbjct: 25 QVEYAREAVRRGTTAVGIKCKDGVVLAVDRRITSKLIDVSSIEKIFQIDDHIVAATSGLV 84
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +++ AR EA R YG + ++ L +++ AYT + RP+G ++++ T
Sbjct: 85 ADARVLIDRARIEAQMNRVSYGEAITVEALAKKICDIKQAYTQHGGARPFGLALLI-TGI 143
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D +++ DPSG Y A+G + A +E ++TV E + A +
Sbjct: 144 DRHSARLFETDPSGALIEYKATAIGSGRPIAMEVLESKYDENMTVSEGMELALYALSKTT 203
Query: 214 DELKDKQFELEL 179
+ELK + ++ +
Sbjct: 204 EELKPENIDMAI 215
>UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4;
Eukaryota|Rep: Proteasome subunit alpha type-4 -
Dictyostelium discoideum (Slime mold)
Length = 250
Score = 124 bits (298), Expect = 3e-27
Identities = 73/233 (31%), Positives = 122/233 (52%), Gaps = 3/233 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN--KRIFHIDEHVGMAVAG 581
QVEYA A+ ++G +G+ KDG+V A EK T+KL + + +++F IDEHV AVAG
Sbjct: 20 QVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSSTSISEKMFKIDEHVVCAVAG 79
Query: 580 LISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGT 401
+ SDA ++ AR + + QY P+P++ L ++ YT Y +RP+G S +
Sbjct: 80 ITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQYGGLRPFGVSFLYAG 139
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAV-GKAKQAAKTEIEKLKLGDLTVKELVREAARIIY 224
W + G Q+Y DPSG + ++ G+ Q A++ + D+++KE ++ A +++
Sbjct: 140 WDRHYGFQLYQSDPSGNFAGWKATSIGGENSQVAQSVLRSNYKPDISLKEALQLALKVLT 199
Query: 223 LVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSDE 65
D +LE S+ +K + + V + T AE A D+E E
Sbjct: 200 KTMDRSNINSEKLEFSYFTK----QGDNVVYHIFTAAELDAFIKETDLEQETE 248
>UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1;
Methanocorpusculum labreanum Z|Rep: Proteasome alpha
subunit - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 272
Score = 121 bits (291), Expect = 2e-26
Identities = 60/153 (39%), Positives = 94/153 (61%), Gaps = 3/153 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ T +G++ K GVV V+K + S+L EP + ++IF IDEH+G+A +GL+
Sbjct: 26 QVEYAREAVKRGTTAVGIKCKTGVVLLVDKRVNSRLLEPSSIEKIFRIDEHIGVASSGLV 85
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS-VVMGTW 398
DAR +V+ AR EA R YG PV ++ L +++ +M +YTL+ RPYG + ++ G
Sbjct: 86 GDARILVDRARIEAQINRVSYGEPVDVETLAKKLCDHMQSYTLFGGARPYGTALLIAGAE 145
Query: 397 TDYEGPQMYML--DPSGVSFSYFGCAVGKAKQA 305
+ G + ++ DPSG Y +G + A
Sbjct: 146 SSPTGTKYHLFETDPSGTLLEYSATGIGIGRPA 178
>UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6;
Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus
acidocaldarius
Length = 242
Score = 121 bits (291), Expect = 2e-26
Identities = 60/176 (34%), Positives = 101/176 (57%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QV+YA +AV+ T +G++ K GVV EK ++L + ++IF +D+HVG AGL
Sbjct: 25 QVDYAFEAVKRGWTTLGVKTKSGVVLLAEKRKATQLLDVDGIEKIFMLDDHVGCTFAGLA 84
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SD R +++ ARS+A +R Y P+ ++YL + +S AYT + VRP+G ++++G
Sbjct: 85 SDGRILIDYARSQALQHRLIYDEPISIEYLTKVISDVKQAYTQHGGVRPFGVALIVGGID 144
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
+ P++ M +PSG Y+ A+G+ A +EK DL ++ + A R +
Sbjct: 145 KGKQPKLLMTEPSGQFMPYYAVAIGQGGYTATEYLEKNYKEDLDIQSTILLALRAL 200
>UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8;
Halobacteriaceae|Rep: Proteasome subunit alpha 1 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 118 bits (284), Expect = 2e-25
Identities = 75/231 (32%), Positives = 126/231 (54%), Gaps = 1/231 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ IG+R DGVV AV+K I S L E + ++I D+H+G+A AG +
Sbjct: 25 QVEYAREAVKRGTASIGVRTSDGVVLAVDKRIRSPLMERSSVEKIHKADDHIGIASAGHV 84
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DARQ+++ AR +A + +YG PV ++ L + ++ Y+ YT RP+G ++++G
Sbjct: 85 ADARQLIDFARRQAQVNQLRYGEPVGVETLTKEITDYIQQYTQVGGARPFGVALIIGGIV 144
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
+ E P+++ DPSG + + AVG + + +E+ + + E V A + V+
Sbjct: 145 NGE-PRLFETDPSGTPYEWKALAVGADRGDIRDYLEEHYDEGMDLDEGVDLALAALASVN 203
Query: 214 -DELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSDE 65
DEL + + V +T G+ T+ E +A A AD+ D+ E
Sbjct: 204 DDELSPEGIGVATVDVETETFGQ--------LTDEEKEAHLAEADLLDTGE 246
>UniRef50_P23638 Cluster: Proteasome component Y13; n=3;
Saccharomycetaceae|Rep: Proteasome component Y13 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 258
Score = 116 bits (280), Expect = 5e-25
Identities = 61/198 (30%), Positives = 106/198 (53%), Gaps = 1/198 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGL 578
QVEYA +++ ++GT IG+ DG+V A E+ +TS L E + ++++ +++ + +AVAGL
Sbjct: 21 QVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGL 80
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+DA ++ TAR A NY Y +P++ L R+S YT + +RP+G S + +
Sbjct: 81 TADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGY 140
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
D G Q+Y +PSG + +VG AA+T ++ D+ V + + A + +
Sbjct: 141 DDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKT 200
Query: 217 HDELKDKQFELELSWVSK 164
D LE + + K
Sbjct: 201 TDSSALTYDRLEFATIRK 218
>UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;
Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo
sapiens (Human)
Length = 241
Score = 116 bits (279), Expect = 6e-25
Identities = 66/200 (33%), Positives = 115/200 (57%), Gaps = 5/200 (2%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +A++ T IG++ +GV AVEK ITS L EP + ++I ID H+G A++GLI
Sbjct: 23 QVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLI 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSA-----VRPYGCSVV 410
+DA+ +++ AR E N+ Y + ++ + + VS + A RP+G +++
Sbjct: 83 ADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALL 142
Query: 409 MGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARI 230
G D +GPQ++ +DPSG A+G A + A++ ++++ +T+KE ++ + I
Sbjct: 143 FG-GVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLII 201
Query: 229 IYLVHDELKDKQFELELSWV 170
+ V +E K +EL+ V
Sbjct: 202 LKQVMEE-KLNATNIELATV 220
>UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2;
Eukaryota|Rep: Proteasome subunit alpha type-5 -
Entamoeba histolytica
Length = 247
Score = 115 bits (277), Expect = 1e-24
Identities = 65/203 (32%), Positives = 117/203 (57%), Gaps = 6/203 (2%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +A++ TVIG++ K+GVV AVEK I+S L + ++I ID+H+G AV+GL
Sbjct: 23 QVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLMLGSSIEKIIEIDDHIGAAVSGLT 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYS-----AVRPYGCSVV 410
+DAR +++ AR EA N+R Y P+ ++ + + +S + S RP+G +++
Sbjct: 83 ADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLSLRFGEGSRKKKVMSRPFGVALL 142
Query: 409 MGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKEL-VREAAR 233
+ D GP+++ DPSG+ ++ A G +AA++ + + +T++E + +
Sbjct: 143 I-AGVDETGPRLFQTDPSGMFIEFYAKATGAGTEAAQSILHEKYNKSMTLREAEILALST 201
Query: 232 IIYLVHDELKDKQFELELSWVSK 164
+ ++ ++L K E+ L V K
Sbjct: 202 LKQVMEEKLNSKNVEVALVTVEK 224
>UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia
intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia
ATCC 50803
Length = 244
Score = 114 bits (275), Expect = 2e-24
Identities = 57/172 (33%), Positives = 99/172 (57%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA KAV + + + +DG+VF +K + SKL + +++I+ ID H+ AV+GL
Sbjct: 19 QVEYAIKAVTIAAPCLAILAQDGIVFVAQKKLPSKLSDQQTSEKIYKIDSHIVCAVSGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SDA +++ AR+ + + + Y P+P++ L + +S YT + +RPYG S + G W
Sbjct: 79 SDANILIDEARTYSQKWLAVYDEPIPVEVLVQYISDVKQNYTHHGGLRPYGVSFLFGGWD 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
+ G Q+Y DPSG ++ ++G + + + K + D + K L++EA
Sbjct: 139 AHLGFQLYQTDPSGNYSAWVATSIGGSAPEIASAL-KQNIADSSQKILLKEA 189
>UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum
pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix
Length = 258
Score = 114 bits (274), Expect = 3e-24
Identities = 59/188 (31%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QV YA +AV+ T +G++ +GVV A EK L + +I+ ID+H+G+A AG+
Sbjct: 27 QVRYAFEAVKKGWTSLGIKTNEGVVIAAEKRFIGPLVDIDDIDKIYKIDDHIGVAFAGMG 86
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R +++ AR +R YG P P++ + + V+ AYT + VRP+G +++
Sbjct: 87 GDGRILIDYARVFTVRHRLLYGEPPPVELVAKVVADVKQAYTQHGGVRPFGVALIFAGVN 146
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIY-LV 218
++Y DP G FS+ A+G +Q A EK D++++E + A +I+Y ++
Sbjct: 147 PDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEMFEKHYRSDMSLEEATKLALKILYAII 206
Query: 217 HDELKDKQ 194
++DK+
Sbjct: 207 RKTVEDKE 214
>UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24;
Bilateria|Rep: Proteasome subunit alpha type-7 -
Carassius auratus (Goldfish)
Length = 251
Score = 114 bits (274), Expect = 3e-24
Identities = 59/158 (37%), Positives = 93/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ T +G+RGKD VV VEK +KL E ++I +DEHV MA AGL
Sbjct: 20 QVEYAQEAVKKGSTAVGIRGKDIVVLGVEKKSVAKLQEERTVRKICALDEHVCMAFAGLT 79
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR ++ AR E ++R PV ++Y+ ++ YT + RP+G S ++
Sbjct: 80 ADARIVINRARVECQSHRLTVEDPVTVEYITRYIATLKQRYTQSNGRRPFGISALI-VGF 138
Query: 394 DYEG-PQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
D++G P++Y DPSG ++ A+G++ + + +EK
Sbjct: 139 DFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEK 176
>UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 288
Score = 113 bits (271), Expect = 6e-24
Identities = 60/157 (38%), Positives = 89/157 (56%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA +AV+ V+G R + VV A K TS+L G K+++ ID H+G+AV+G+
Sbjct: 50 QIEYAMEAVKQGTAVVGARNDEIVVLACIKRSTSRL--AGYQKKLYKIDNHIGVAVSGIT 107
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DA+ I RSE NY Y SP+PL L R+ + T RP+G +++ +
Sbjct: 108 ADAKVICNYLRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQEYGRRPFGVGLLLAGF- 166
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
D GP ++ PSG F Y+ A+G QA+KT +EK
Sbjct: 167 DESGPHLFETCPSGNCFEYYSIAIGSRSQASKTYLEK 203
>UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha
subunit - Entamoeba histolytica HM-1:IMSS
Length = 242
Score = 112 bits (270), Expect = 8e-24
Identities = 61/212 (28%), Positives = 116/212 (54%), Gaps = 2/212 (0%)
Frame = -2
Query: 754 QVEYAAKAVE-NSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KA + S T +G+ + +K + +L +P + I +HVG ++G+
Sbjct: 21 QVEYALKATKCESLTTVGVCSDEAACIITQKKLPDRLVDPSTVTHLHRISKHVGCCMSGI 80
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+D + I + ++ AS ++ YG +P+ + ++ + + T ++ +RP+G S + W
Sbjct: 81 YADGKVIAQRSQYYASKFQLDYGYEMPVSLVAKKTADFAQMLTQHAYMRPFGVSSMFIGW 140
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKL-GDLTVKELVREAARIIYL 221
+ GPQ++ DP+G ++ GCA G+ +Q A +EK K+ +LTV ++V +A +
Sbjct: 141 DEVSGPQLWRSDPAGSVAAFRGCAAGEKEQEAFNNLEKKKITKELTVDQVVCQALDCLQT 200
Query: 220 VHDELKDKQFELELSWVSKDTKGRHELVPREL 125
V + K ++E++ V+KD K H L +E+
Sbjct: 201 VTSS-EFKATDIEIAIVTKDNKLFHLLSQQEI 231
>UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7;
Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum
aerophilum
Length = 243
Score = 112 bits (270), Expect = 8e-24
Identities = 63/212 (29%), Positives = 114/212 (53%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ +G++ K GVV EK S L++ + ++I+ IDEHV + +GL+
Sbjct: 24 QVEYAGEAVKRGWPTVGVKCKAGVVLTAEKRKISALFDSSSLEKIYLIDEHVAASPSGLL 83
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +++ AR A ++R Y P+ +++L + V YT + RP+G ++++
Sbjct: 84 ADARILIDYARDVALSHRFIYDEPIDVEFLTKAVCNLKQQYTQFGGARPFGVALLI-AGV 142
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D G ++Y DPSGV YF A+G +EK D+ + E + A + +
Sbjct: 143 DRHGARLYQTDPSGVYIGYFATAIGAESGTITEFLEKNYKFDMEMGECIELALKALASA- 201
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRELAT 119
E+ D +E+++ + + K ++ E+A+
Sbjct: 202 VEITDSA-NVEVAYATIEEKKMRKMSQDEVAS 232
>UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48;
Eukaryota|Rep: Proteasome subunit alpha type-2 -
Drosophila melanogaster (Fruit fly)
Length = 234
Score = 112 bits (269), Expect = 1e-23
Identities = 63/172 (36%), Positives = 90/172 (52%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA AV +G+ +GVV A E S LYE + R+ I H+GM +G+
Sbjct: 21 QLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHRVEMIYNHIGMVYSGMG 80
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R +V+ AR A Y Y P+P+ L +RV+ M YT VRP+G S+++ W
Sbjct: 81 PDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQSGGVRPFGVSLLICGW- 139
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
D + P +Y DPSG F++ A+GK KT +EK DL + + V A
Sbjct: 140 DNDRPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSEDLELDDAVHTA 191
>UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9;
Eukaryota|Rep: Proteasome subunit alpha type -
Cryptosporidium parvum Iowa II
Length = 271
Score = 111 bits (267), Expect = 2e-23
Identities = 59/194 (30%), Positives = 105/194 (54%), Gaps = 1/194 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGL 578
QVEYA +A+ N+ +G+ K+GV+ +K I SKL + G + ++I+ ID H+ AVAGL
Sbjct: 30 QVEYALEAINNAAPTVGILCKEGVILGADKAIVSKLLDQGKSLEKIYTIDRHIIAAVAGL 89
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+DA ++ AR ++ Y+ YG P++ L ++ +YT + +RP+G S + +
Sbjct: 90 TADANILIAQARIDSQRYQYTYGEEQPVEQLVTQICDRKQSYTQFGGLRPFGVSFLFAGY 149
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
G Q+Y DPSG + A+G+ Q A + +++ DLT+++ + A+++
Sbjct: 150 DKNYGYQLYQSDPSGNFSGWKATAIGQNNQTATSLLKQEWNEDLTLEQGLHLVAKVLTKT 209
Query: 217 HDELKDKQFELELS 176
D + E S
Sbjct: 210 MDTTSPTADKFEFS 223
>UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1;
Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha
subunit - Hyperthermus butylicus (strain DSM 5456 / JCM
9403)
Length = 243
Score = 111 bits (267), Expect = 2e-23
Identities = 64/209 (30%), Positives = 110/209 (52%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +A + T++G+R +DGVV EK TS L + ++++ +DEH+G G
Sbjct: 27 QVEYAMEAAKRGWTMVGVRARDGVVIVAEKKKTSPLIDIEQLEKVYMVDEHIGAGFVGFG 86
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SD R +++ AR A Y+ YG +P++YL ++ M YT + VRP+G ++++
Sbjct: 87 SDGRVLIDYARQLAIQYKFIYGEKIPVEYLTRQICDLMQLYTQHGGVRPFGVTLLI-VGV 145
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D GP++++ +PSG SY +G+ A +++ D+ V+ + R + V
Sbjct: 146 DDSGPKLFVAEPSGQYMSYKAHGLGQGGGQAIEILQREYRDDIDVEGAILLGIRAVASVM 205
Query: 214 DELKDKQFELELSWVSKDTKGRHELVPRE 128
E K LE+ V+ GR + +E
Sbjct: 206 -EGKPTPETLEVG-VADTRTGRFRKLTKE 232
>UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4;
Thermoplasmatales|Rep: Proteasome subunit alpha -
Picrophilus torridus
Length = 234
Score = 111 bits (266), Expect = 2e-23
Identities = 65/191 (34%), Positives = 103/191 (53%), Gaps = 1/191 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ T +G++ KDGV EK + S+L E + ++I ID+ V +GL+
Sbjct: 23 QVEYAREAVKKGSTALGIKFKDGVALISEKKVRSRLVEKTSLEKIQLIDDRVAAVTSGLV 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +++ AR + YGS + ++ L +RV+ M YT Y VRPYG S++
Sbjct: 83 ADARVLIDFARISDQQEKVTYGSLMNIENLVKRVADQMQQYTQYGGVRPYGVSIIF-AGL 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA-ARIIYLV 218
D GP+++ DP+G Y ++G K +EK +L+ E +R A + V
Sbjct: 142 DSIGPRLFDCDPAGTINEYKCVSIGAGKDQVTAYLEKEYKENLSEDEAIRMGIAALKSAV 201
Query: 217 HDELKDKQFEL 185
DE K+ E+
Sbjct: 202 ADESSMKEPEI 212
>UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole
genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome
undetermined scaffold_17, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 245
Score = 110 bits (265), Expect = 3e-23
Identities = 71/213 (33%), Positives = 108/213 (50%), Gaps = 3/213 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KAV+ SG T IG++G D V EK + KL + + +F++ E +G G+
Sbjct: 23 QVEYAFKAVKTSGLTSIGVKGTDTVCLITEKRVPDKLIDEKSVTNLFNVSEKIGALTTGI 82
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
SDAR +V R EA +R + G P+ L++R++ T Y +R YG ++ +
Sbjct: 83 PSDARALVTRMRYEAGEFRLKNGYYCPVDVLSKRMADLAQTNTQYYQMRSYGVETILCQY 142
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARIIY 224
D GP +Y LDPSG Y A G +Q A +EK K DL E + A + +
Sbjct: 143 DDELGPLLYKLDPSGHYSGYKATASGVKEQEAINYLEKQIKKKADLNYDETIMLAIQTLQ 202
Query: 223 LVHDELKDKQFELELSWVSKDTKGRHELVPREL 125
V + K ++E+ V+K K H+L ++
Sbjct: 203 NVISQ-DFKPTDIEVGIVTKQDKKFHKLTNEQV 234
>UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13;
Eukaryota|Rep: Proteasome subunit alpha type-7 -
Trypanosoma brucei brucei
Length = 247
Score = 110 bits (264), Expect = 4e-23
Identities = 62/190 (32%), Positives = 98/190 (51%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV +G++GKD ++FAVEK KL + ++I+ +DEH+ +A AGL
Sbjct: 18 QVEYAQEAVRKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKIYKLDEHIYLASAGLS 77
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +V A+ E +R Y + + L V+ T S RPYG S ++G +
Sbjct: 78 ADARVVVNHAQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQSSGSRPYGVSTIIGGFN 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
+ PQ++ +PSG S ++ A+G+ + +EK +T V A + + L
Sbjct: 138 ENGQPQLWKTEPSGTSSAWNAAAIGRNDKVVLEFMEKNYQDGMTRDRCVHFAIKAL-LEA 196
Query: 214 DELKDKQFEL 185
E K EL
Sbjct: 197 VESGSKNIEL 206
>UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4;
n=5; Eukaryota|Rep: Probable proteasome subunit alpha
type-4 - Schizosaccharomyces pombe (Fission yeast)
Length = 248
Score = 110 bits (264), Expect = 4e-23
Identities = 59/200 (29%), Positives = 104/200 (52%), Gaps = 1/200 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGL 578
QVEYA +A+ ++G +G+ KDG+V A EK +TSKL E + ++++HI +++ AVAGL
Sbjct: 20 QVEYALEAINHAGVALGIVAKDGIVLAAEKKVTSKLLEQEESAEKLYHIGDNMLCAVAGL 79
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+DA ++ AR Y + +P + L RV YT Y +RP+G S + W
Sbjct: 80 TADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQGYTQYGGLRPFGVSFLYAGW 139
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
G Q++ +PSG S+ ++G + ++ + + D+ + E A + +
Sbjct: 140 DHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYKDDINLDEASAMAVKFLSKT 199
Query: 217 HDELKDKQFELELSWVSKDT 158
D ++E + ++KDT
Sbjct: 200 LDSNSLTHEKIEFATITKDT 219
>UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7;
Trypanosomatidae|Rep: Proteasome subunit alpha type -
Leishmania major
Length = 285
Score = 109 bits (263), Expect = 5e-23
Identities = 64/204 (31%), Positives = 113/204 (55%), Gaps = 7/204 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPG-------ANKRIFHIDEHVG 596
QVEYA +A++ +GTVIG+ KDGVV A EK++ L++ + ++++ I EH+G
Sbjct: 20 QVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSENMQDKNISGEKMYKIAEHIG 79
Query: 595 MAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS 416
+VAG+ SDA ++ AR A ++ + P+ ++ L + YT Y VRPYG S
Sbjct: 80 CSVAGVTSDAYALLNYARLSALRHQYTFQEPIAIEDLCRILCDEKQLYTQYGGVRPYGVS 139
Query: 415 VVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAA 236
++ W Y G Q+Y +PSG ++ A+G+ Q A + ++K ++T+++ + A
Sbjct: 140 FLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSLLKKDWHENMTLEDGMLLAL 199
Query: 235 RIIYLVHDELKDKQFELELSWVSK 164
R++ D K +E++ + K
Sbjct: 200 RVLGKTMDTAKIDLGRVEVAVMRK 223
>UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;
Eukaryota|Rep: Alpha 2 subunit of 20S proteasome -
Ostreococcus tauri
Length = 270
Score = 108 bits (260), Expect = 1e-22
Identities = 55/172 (31%), Positives = 91/172 (52%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+++A A+ T +G++ DGVV A EK + S L + K+I + + +G+A +G+
Sbjct: 56 QIKHALAAISAGATSLGIKAVDGVVLATEKKLPSTLVDASTVKKIATLTDDIGIAYSGMG 115
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R + AR E Y Y +P+ L + M +T VRP+G S++M +
Sbjct: 116 PDFRVLTRMARKETQTYYRTYKESIPVSQLVRETATVMQEFTQQGGVRPFGVSLLMAGY- 174
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
D GP +Y +DPSG F++ A+GK AKT +EK D+ +++ + A
Sbjct: 175 DESGPSLYQVDPSGSYFAWKASAIGKNMVNAKTFLEKRYSDDIELEDAIHTA 226
>UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69;
Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo
sapiens (Human)
Length = 246
Score = 108 bits (259), Expect = 2e-22
Identities = 62/199 (31%), Positives = 106/199 (53%), Gaps = 3/199 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KA+ G T + +RGKD V +K + KL + +F I E++G + G+
Sbjct: 24 QVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGM 83
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+D+R V+ AR EA+N++ +YG +P+ L +R++ YT + +RP GC +++
Sbjct: 84 TADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGI 143
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARIIY 224
+ +GPQ+Y DP+G + A G + + + +EK K D T ++ V A +
Sbjct: 144 DEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLS 203
Query: 223 LVHDELKDKQFELELSWVS 167
V + K E+E+ V+
Sbjct: 204 TVL-SIDFKPSEIEVGVVT 221
>UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2;
Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome
endopeptidase complex - Halorubrum lacusprofundi ATCC
49239
Length = 268
Score = 107 bits (258), Expect = 2e-22
Identities = 69/233 (29%), Positives = 120/233 (51%), Gaps = 1/233 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV +G+R DGVVF +S L E + +++ +D+H+G A AG +
Sbjct: 25 QVEYAREAVSRGAPSVGVRTADGVVFVAMSRPSSTLMEAESIEKLHKLDDHLGTASAGHV 84
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DARQ+++ AR ++ R +YG PV ++ L + V+ ++ T RPYG ++++G
Sbjct: 85 ADARQLIDLARRQSQGNRLRYGEPVGVETLTKFVTDHIQENTQRGGTRPYGAALLIG-GI 143
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D P+++ DPSG + +G + + +E+ +L++ V E A H
Sbjct: 144 DNGEPRLFAADPSGTPNEWKATVIGGGRSDIQGHLEENWTEELSLDAGV-ELAIAALAAH 202
Query: 214 DELKDKQFE-LELSWVSKDTKGRHELVPRELATEAENQAKQALADIEDSDEGE 59
D+ +FE +L+ + + VP E TEA A + + ++ DE E
Sbjct: 203 DD----EFEPTDLAVATVTEADGYRTVPVEEVTEAFEAAGLTVEEDDEGDEEE 251
>UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1;
Babesia bovis|Rep: Proteasome alpha 5 subunit, putative
- Babesia bovis
Length = 250
Score = 107 bits (257), Expect = 3e-22
Identities = 60/200 (30%), Positives = 114/200 (57%), Gaps = 10/200 (5%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA A++ T + + K+GV+FA E + S L E + ++I ID H+G ++GLI
Sbjct: 23 QVEYALGAIKLGSTALAIATKEGVIFASEHRVNSPLMESVSLEKIMEIDTHIGCTMSGLI 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVS-MYMHAYTLY------SAVRPYGCS 416
+DAR +++ R E +N+R Y P+ ++ E ++ M + ++ + RP+G +
Sbjct: 83 ADARTLIDHGRLECANHRFVYNEPLAIRSCVESIADMALDFSDIFDTRKKKTMSRPFGVA 142
Query: 415 VVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKE---LVR 245
+++G D +GP ++ +DPSG S Y A+G A++ A++ +++ D++ ++ LV
Sbjct: 143 LLVG-GIDIDGPSIWCVDPSGTSIKYKASAIGSAQEGAESVLQERYRDDMSFRDAELLVL 201
Query: 244 EAARIIYLVHDELKDKQFEL 185
E R ++ D++ K E+
Sbjct: 202 EVLR--QVMKDQMTTKNIEM 219
>UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4;
Pezizomycotina|Rep: Proteasome subunit alpha type -
Chaetomium globosum (Soil fungus)
Length = 267
Score = 107 bits (257), Expect = 3e-22
Identities = 74/237 (31%), Positives = 120/237 (50%), Gaps = 6/237 (2%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYAA+AV+ V+G+ K VV K +L K++F IDEHVG+A+AGL
Sbjct: 21 QVEYAAEAVKQGSVVVGIASKTHVVLVAIKRNAEEL--SSYQKKLFPIDEHVGIAIAGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SDAR + + + +R +G +P++ L E + T + RPYG +++
Sbjct: 79 SDARVLSNFMKQQCLGHRLTFGRSMPVRTLVEIIGSKAQINTQHYGKRPYGVGLLVAGVD 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKL--KLGDLTVKELVREAARII-- 227
D+ GP ++ PSG++ A+G Q A+T +EK K D +EL+R R +
Sbjct: 139 DH-GPHLFEFQPSGMTEEMVAFAIGARSQMARTYLEKNIDKFADCDREELIRHGLRALKE 197
Query: 226 YLVHD-ELKDKQFELELSWVSKDTKGRHELVPRELATEAENQA-KQALADIEDSDEG 62
LV D EL + +S V K G ++ P ++ + + A +++AD ++ G
Sbjct: 198 SLVQDRELTIDNTSVGVSGVVKAEDGSSKVEPFQVYDQQDVAAWIESVADDKEGGAG 254
>UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7;
n=3; Ascomycota|Rep: Probable proteasome subunit alpha
type-7 - Schizosaccharomyces pombe (Fission yeast)
Length = 259
Score = 107 bits (257), Expect = 3e-22
Identities = 69/223 (30%), Positives = 112/223 (50%), Gaps = 5/223 (2%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEY +AV T I LRG + +V VE+ KL ++I +D HV +A AGL
Sbjct: 19 QVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKIAMVDNHVCLAFAGLN 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS-VVMGTW 398
+DAR +++ AR EA N++ PV ++YL V+ YT VRP+G S ++ G
Sbjct: 79 ADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSGGVRPFGVSTLIAGFD 138
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
P++Y +P+G+ ++ A+G+A +AA+ +EK L+ E + A + V
Sbjct: 139 VGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKEGLSRDETIHLAVSSLLEV 198
Query: 217 HDELKDKQFELELSWVSKDTKGRH----ELVPRELATEAENQA 101
+ EL + KD + H + + +E+ E E +A
Sbjct: 199 -VQTASGNIELAIMDPGKDVEFLHSDKIDTIVKEIQDEKEAEA 240
>UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16;
Drosophila|Rep: Proteasome subunit alpha type-7-1B -
Drosophila melanogaster (Fruit fly)
Length = 252
Score = 107 bits (257), Expect = 3e-22
Identities = 58/179 (32%), Positives = 97/179 (54%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV TV+GLR + +V VEK L E ++I +D+HV M +GL
Sbjct: 20 QVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLT 79
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +V A+ EA ++R + P ++Y+ ++ YT + RP+G S ++G +
Sbjct: 80 ADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFD 139
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
+ P ++ DPSG+ + + G++ Q + +EK LT+ + EAA I ++V
Sbjct: 140 EDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIAD---EAAAIKHIV 195
>UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54;
Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo
sapiens (Human)
Length = 234
Score = 107 bits (256), Expect = 4e-22
Identities = 58/172 (33%), Positives = 91/172 (52%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA AV +G++ +GVV A EK S LY+ + ++ I +H+G+ +G+
Sbjct: 21 QIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKVEPITKHIGLVYSGMG 80
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R +V AR A Y Y P+P L +RV+ M YT VRP+G S+++ W
Sbjct: 81 PDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWN 140
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
+ P ++ DPSG F++ A+GK KT +EK DL +++ + A
Sbjct: 141 EGR-PYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTA 191
>UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;
core eudicotyledons|Rep: Proteasome subunit alpha
type-1-A - Arabidopsis thaliana (Mouse-ear cress)
Length = 278
Score = 106 bits (255), Expect = 5e-22
Identities = 68/198 (34%), Positives = 105/198 (53%), Gaps = 2/198 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ IGLR + VV A S+L ++IF +D+H+G+A+AGL
Sbjct: 21 QVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSEL--SSHQRKIFKVDDHIGVAIAGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D R + RSE+ N+ Y SP+P+ L ++ T S RPYG +++G
Sbjct: 79 ADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQRSWKRPYGVGLLVG-GL 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKL--KLGDLTVKELVREAARIIYL 221
D G +Y PSG F Y A+G QAAKT +E+ GD + ++L+++A I
Sbjct: 138 DESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRFESFGDSSREDLIKDA---ILA 194
Query: 220 VHDELKDKQFELELSWVS 167
V + L+ + + L V+
Sbjct: 195 VRETLQGETLKSSLCTVA 212
>UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15;
Eukaryota|Rep: Proteasome subunit alpha type-6-A -
Arabidopsis thaliana (Mouse-ear cress)
Length = 246
Score = 106 bits (254), Expect = 7e-22
Identities = 68/214 (31%), Positives = 113/214 (52%), Gaps = 4/214 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KAV+ +G T IG+RGKD V +K + KL + + +F I +++G+ G+
Sbjct: 24 QVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSVTHLFPITKYIGLVATGI 83
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYG-CSVVMGT 401
+DAR +V+ AR++A+ +R YG +P+ L + ++ YT ++ +RP G ++VMG
Sbjct: 84 TADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYTQHAYMRPLGVVAMVMGV 143
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIE-KLKLG-DLTVKELVREAARII 227
+ GP +Y DP+G + + + G +Q A +E K+K T E V+ A +
Sbjct: 144 -DEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKENPSFTFDETVQTAISAL 202
Query: 226 YLVHDELKDKQFELELSWVSKDTKGRHELVPREL 125
V E K E+E+ V + L E+
Sbjct: 203 QSVLQE-DFKATEIEVGVVRAENPEFRALTTEEI 235
>UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:
NEQ521 - Nanoarchaeum equitans
Length = 250
Score = 105 bits (252), Expect = 1e-21
Identities = 58/202 (28%), Positives = 108/202 (53%), Gaps = 2/202 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA V+ S T IG+ K GV+ +K I K P + ++++ +D+HV A AG+I
Sbjct: 27 QVEYARTTVKQSPTAIGMLYKTGVLVIGDKKIVEKFVIPSSIEKVYIVDDHVIAAPAGII 86
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R ++E AR A Y+ YG P+ ++ L + ++ YT VRP+G S++
Sbjct: 87 GDGRVLIERARVIAQTYKYFYGHPIDIRGLVKEIADIKQEYTQIGGVRPFGVSIIF-AGI 145
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D G +++ +P G+ + Y +G+ +Q + K +L++K+ + + +Y +
Sbjct: 146 DDTGKHIFVTEPGGMFWEYKLAVIGEGEQKVLDYLGKEYNENLSLKKAIELGLKALYNFY 205
Query: 214 DELKDK--QFELELSWVSKDTK 155
E ++ +L++++V + TK
Sbjct: 206 KENNNELTAEKLDIAYVDEKTK 227
>UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;
n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta
subunit - Cenarchaeum symbiosum
Length = 245
Score = 105 bits (252), Expect = 1e-21
Identities = 69/220 (31%), Positives = 117/220 (53%), Gaps = 2/220 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA + V +G++ G+V AVE+ +L ++IF +D+H+G+A AG I
Sbjct: 23 QVEYAIETVRRGTIAVGVKSTGGIVIAVEEK-PRRLQISDTIQKIFQVDDHLGVAAAGYI 81
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
DAR VE AR + + R Y V ++ + + ++ +T Y+ VRP+G ++++G
Sbjct: 82 PDARSQVENARFFSQSNRMMYDESVEVEAVAKHLADQCQQFTQYAGVRPFGVALIIGGVD 141
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK-LKLGDLTVKELVREAARIIYLV 218
D Q+++ DPSG SY A+G + +EK K G ++++ AA I +
Sbjct: 142 DGGKGQLFLTDPSGTYISYDAIAIGAGSEQVTEFLEKSYKPG--SMEDAAVLAAAAIRIA 199
Query: 217 HDELKDKQFELELSWVSKDTKGRHELVP-RELATEAENQA 101
+E D + + ++ VS D + R E+VP E+A+ A A
Sbjct: 200 GEE-TDTESHIRMARVSADNR-RFEMVPDGEVASFAAKAA 237
>UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2;
Giardia intestinalis|Rep: Proteasome subunit alpha type
- Giardia lamblia ATCC 50803
Length = 214
Score = 103 bits (248), Expect = 4e-21
Identities = 54/163 (33%), Positives = 92/163 (56%), Gaps = 1/163 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVE+A KAVE + + +R G+V A+E+ T++L +P A+++IF +D+H+ AGL
Sbjct: 20 QVEHAHKAVERGTSAVAVRSAAGIVLAIERKQTARLQDPRASQKIFDVDDHIIATFAGLT 79
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +++ AR E YR Y ++ + + V+ + ++T RP+G S+++
Sbjct: 80 ADARVLIDRARLECQAYRMTYDVAPSVEIIAKAVASILQSHTHRGGTRPFGVSIIL-AGN 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIE-KLKLGD 269
D G ++M DPSGV + A+G +E KLK G+
Sbjct: 139 DLNGSHVFMCDPSGVYTEWKALAIGNQCVTIIEFLEKKLKEGE 181
>UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei rhodesiense
Length = 266
Score = 103 bits (248), Expect = 4e-21
Identities = 62/179 (34%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVF-AVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA +AV N +G++G D VV A+++ S L ++ F +DEHVGMA++GL
Sbjct: 21 QVEYANEAVNNGSAAVGVKGADYVVLTALKRNPVSGL--SSYQEKAFKLDEHVGMAISGL 78
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
++D R + R+E NYR + S PL L + V + ++ RP+G +++ +
Sbjct: 79 VADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRHIQFAGKRPFGVGLLIAGY 138
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLG--DLTVKELVREAARII 227
D +GP++Y PSG F + A+G QAA+T +E+ G + ELV A R +
Sbjct: 139 -DRQGPRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHFRGFPACDLDELVMHALRAL 196
>UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;
Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo
sapiens (Human)
Length = 261
Score = 103 bits (247), Expect = 5e-21
Identities = 59/200 (29%), Positives = 107/200 (53%), Gaps = 2/200 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLY-EPGANKRIFHIDEHVGMAVAGL 578
QVEYA +A+ ++GT +G+ DGV+ A E+ KL E +++I+ ++E + +VAG+
Sbjct: 20 QVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGI 79
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
SDA + R A Y QY P+P + L + AYT + RP+G S++ W
Sbjct: 80 TSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGW 139
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK-LKLGDLTVKELVREAARIIYL 221
+ G Q+Y DPSG + +G AA + +++ K G++T+K + A +++
Sbjct: 140 DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNK 199
Query: 220 VHDELKDKQFELELSWVSKD 161
D K ++E++ ++++
Sbjct: 200 TMDVSKLSAEKVEIATLTRE 219
>UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY
SUBUNIT 8 - Encephalitozoon cuniculi
Length = 242
Score = 102 bits (245), Expect = 8e-21
Identities = 61/205 (29%), Positives = 106/205 (51%), Gaps = 4/205 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+ YA KA ++ T IG++ K GVV EK S LY ++++I I +G+ G+
Sbjct: 18 QLSYAQKAADSGDTCIGMKSKHGVVLLAEKPRVSPLYILESDEKIRKIGNTIGVVCTGMS 77
Query: 574 SDARQIVETARSEASNYRSQYGS-PVP--LK-YLNERVSMYMHAYTLYSAVRPYGCSVVM 407
SD + + +++ + P P +K YLN+ H +T +R G + +
Sbjct: 78 SDTFYVGCAIKDYVFHHKENFNEDPTPGMMKVYLND----IFHYFTRGINLRVLGANTLT 133
Query: 406 GTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
+ D ++ D SG + SY +GK + KTE+EKL + +T++E+V +++
Sbjct: 134 SVYKDGSFSLLHT-DCSGKTLSYKAACIGKGTRRIKTELEKLDIDTMTIEEMVDVGVKVL 192
Query: 226 YLVHDELKDKQFELELSWVSKDTKG 152
Y+ HD KDK+F++E+ S +T G
Sbjct: 193 YMAHDPSKDKEFDIEIGIASMETGG 217
>UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3;
Eukaryota|Rep: Proteasome subunit alpha type - Emiliania
huxleyi
Length = 264
Score = 102 bits (244), Expect = 1e-20
Identities = 53/162 (32%), Positives = 91/162 (56%), Gaps = 5/162 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KA++ SG T +G+RG D V ++ + KLY+P + ++ I ++G+ + G+
Sbjct: 24 QVEYAFKAIKTSGLTSVGVRGADPCVVLTQRKVPDKLYDPESVTNMYAITPNIGLVMTGI 83
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+ DAR V+ R EA+ ++ G +P+ YL +R + YT ++ +RP G ++++
Sbjct: 84 VPDARASVKKLREEAAKFKFNNGYDIPVSYLAKRAADTAQVYTQHANMRPLGIAMII-IG 142
Query: 397 TDYEG----PQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
D EG PQ++ DP+G Y + G +Q A +EK
Sbjct: 143 IDVEGEKKVPQLFRCDPAGYYVGYKATSAGAKEQEANNFLEK 184
>UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family
protein; n=5; Oligohymenophorea|Rep: Proteasome A-type
and B-type family protein - Tetrahymena thermophila
SB210
Length = 267
Score = 101 bits (243), Expect = 1e-20
Identities = 55/156 (35%), Positives = 87/156 (55%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QV+YA KA++ IGLR + V +K SKL G ++IF +D+ +GM VAG+
Sbjct: 38 QVDYATKAIDQGSITIGLRSQKFAVLVAQKRSNSKL--SGYQEKIFQVDDKIGMGVAGIT 95
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR I + R+E N++ YGS P + L ++S T RPYG ++
Sbjct: 96 ADARVICKYMRTECLNHKYVYGSQHPAQRLVIKISEKSQHKTQTYGKRPYGVGTLI-IAQ 154
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIE 287
+ +GP+++ PSG + ++G ++G QAAKT +E
Sbjct: 155 ESDGPKLFQTLPSGDFYEFYGQSIGSRSQAAKTYLE 190
>UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia
intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia
ATCC 50803
Length = 292
Score = 101 bits (242), Expect = 2e-20
Identities = 78/252 (30%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QV+YA KAVE G +G+R GV AV+K I L E + + I++ + +AVAGL
Sbjct: 43 QVDYALKAVEQHGLCVGIRTSGGVALAVQKNIHDIL-EIDSAPCFYQIEDSIVIAVAGLQ 101
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D +V AR A +YR Y VP L +S YM YT Y VRP+GCS+++ +
Sbjct: 102 PDGMVLVSKAREVAESYRENYSRIVPTGVLANSISGYMQLYTHYGEVRPFGCSLLIAGYD 161
Query: 394 DYEGP----------QMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK------------- 284
+Y+L PSG + F A G+ AK E+E
Sbjct: 162 SIASADEPTTLKTKYSLYLLQPSGDITNCFATAAGRHTSQAKVELENHMGPAEKDTNDRF 221
Query: 283 --LK--------LGDLTVKELVREAARIIYLVHDELKDKQFELELSWVSKDTKGRHELVP 134
LK L ++ E + A++I+ HD + D +F L +++S DT +
Sbjct: 222 NHLKRVHNSGGLLTGMSESEAILATAKVIWACHDHINDPEFTLRFAFIS-DT--GTVVYT 278
Query: 133 RELATEAENQAK 98
+E +T+ + Q K
Sbjct: 279 KEQSTDIQEQTK 290
>UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3;
Cryptosporidium|Rep: Proteasome subunit alpha1 -
Cryptosporidium parvum Iowa II
Length = 252
Score = 100 bits (240), Expect = 3e-20
Identities = 51/165 (30%), Positives = 88/165 (53%), Gaps = 7/165 (4%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITS------KLYEPGANKRIFHIDEHVG 596
Q+EY +AV+NS T I ++GKD V EK + + KL +P ++ + +H+G
Sbjct: 24 QIEYTFRAVKNSNITAIAIKGKDTVCIVCEKKVPNQQGQQDKLLDPAYVTSLYKVRKHIG 83
Query: 595 MAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS 416
+ GL D R I+ R A + + G +P+ YL+ +++ YT ++++R G S
Sbjct: 84 AVMLGLAPDCRSIISKCREIAGKFAFEKGVEIPVSYLSHKIADVNQLYTQHASMRLLGAS 143
Query: 415 VVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKL 281
+ + D +GP +Y +DP+G SY CAVG ++ +EK+
Sbjct: 144 GMFISIDDEDGPSLYKIDPAGYFASYRACAVGTKEREGNNALEKI 188
>UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Ustilago maydis (Smut fungus)
Length = 305
Score = 98.7 bits (235), Expect = 1e-19
Identities = 52/158 (32%), Positives = 88/158 (55%), Gaps = 1/158 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KA+ +G T I +RGKD V +K + KL + + IF++ +G + G
Sbjct: 21 QVEYAFKAINTAGLTSIAVRGKDCSVVVGQKKVPDKLIDASSVTNIFNLTPEIGCIMTGR 80
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
++DAR V+ A+ EA++++ +YG + L +R++ YT +A+RPYG S+++
Sbjct: 81 VADARAQVQRAKMEAADFKYKYGYAITPDLLAKRMANMNQVYTQRAAMRPYGVSMILVGI 140
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
GPQ++ +DP+G + A G + A +EK
Sbjct: 141 DAERGPQIFKIDPAGYYVGFRATAAGVKQTEATNFLEK 178
>UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4;
Oryza sativa|Rep: Proteasome subunit alpha type-1 -
Oryza sativa subsp. japonica (Rice)
Length = 270
Score = 98.3 bits (234), Expect = 2e-19
Identities = 60/178 (33%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ +GLR + V A S+L +++F + +H G+A+AGL
Sbjct: 21 QVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASEL--SSHQRKVFRVADHAGVALAGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D R + RSE N+ Y +P+P+ L R++ T S RPYG +++
Sbjct: 79 ADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQRSWKRPYGVGLLV-AGL 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLG--DLTVKELVREAARII 227
D G +Y PSG F Y A+G QAAKT +E+ G D T ++L+++A I
Sbjct: 138 DESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYNDYTPEQLIKDALSAI 195
>UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6;
Eukaryota|Rep: Proteasome subunit alpha type-1 -
Dictyostelium discoideum (Slime mold)
Length = 248
Score = 98.3 bits (234), Expect = 2e-19
Identities = 57/178 (32%), Positives = 95/178 (53%), Gaps = 2/178 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA +AV+ G + L+ K V K +S+L K+IF +D+HVG+A++GL
Sbjct: 21 QIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSEL--GSYQKKIFVVDDHVGIAISGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR + R+E SNY Y S + ++ L +V+ +T RPYG +++ +
Sbjct: 79 ADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQRYGRRPYGVGLLVAGY- 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARII 227
D G +Y PSG + Y ++G Q+AKT +EK + T+++L+ R +
Sbjct: 138 DQLGAHIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEECTLEQLITHGLRAL 195
>UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3;
Basidiomycota|Rep: Proteasome subunit alpha type -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 299
Score = 97.9 bits (233), Expect = 2e-19
Identities = 57/158 (36%), Positives = 82/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ IGLR V K T +L K++ ID+HVG+A+AGL
Sbjct: 21 QVEYALEAVKQGSAAIGLRSNTHAVLLTLKRSTGELAT--YQKKLIRIDDHVGVAIAGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS-VVMGTW 398
SDAR + R +A R YG P+ L + ++ T RPYG +V+G
Sbjct: 79 SDARVLSNYMRQKAMQSRMTYGRATPVARLVQSIADRAQTNTQEYGRRPYGVGFLVIG-- 136
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
D GP ++ P+G +F Y+ ++G Q+AKT +EK
Sbjct: 137 KDETGPHLFEFSPAGTAFEYYAHSIGARSQSAKTYLEK 174
>UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2;
Sophophora|Rep: Proteasome subunit alpha type -
Drosophila melanogaster (Fruit fly)
Length = 289
Score = 97.5 bits (232), Expect = 3e-19
Identities = 67/221 (30%), Positives = 113/221 (51%), Gaps = 4/221 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ +GL+G D V A L + ++I +D+HVGM++AGL
Sbjct: 21 QVEYAMEAVKQGAATVGLKGTDYAVLAA--LCRTSKDTNTLQRKIMPVDDHVGMSIAGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR + + R+E YR Y + P++ L + + T RPYG +++ +
Sbjct: 79 ADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQRYDRRPYGVGLLVAGY- 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARII-- 227
D +GP +Y + P+ + A+G Q+A+T +E+ D + EL+ A + I
Sbjct: 138 DEQGPHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFEDCDMDELICHAIQAIRG 197
Query: 226 YLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQ 104
L D++++ + ++ V KD VP ++ TEAENQ
Sbjct: 198 SLGSDDVEN--LTINVAIVGKD-------VPFKMFTEAENQ 229
>UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7;
Aconoidasida|Rep: Proteasome subunit alpha type -
Plasmodium yoelii yoelii
Length = 278
Score = 97.5 bits (232), Expect = 3e-19
Identities = 57/192 (29%), Positives = 97/192 (50%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVE+A +AV+ G + ++ + V AVEK KL P +++ +DEH +A +GL
Sbjct: 55 QVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPRTTEKLVKLDEHTCLAFSGLN 114
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +V R E Y P P+ Y+ + V+ +T VRP+G + ++ +
Sbjct: 115 ADARILVNKTRLECQRYYLNMDQPAPVDYIAKYVARIQQKFTHRGGVRPFGIATLITGFK 174
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
+ + +Y +PSG+ S+ A+GK + + +EK ++ E + A + I+ V
Sbjct: 175 NNKEICIYQTEPSGIYASWKAQAIGKNAKVVQEFLEKNYQENMEKNECLLLALKAIFEV- 233
Query: 214 DELKDKQFELEL 179
EL K EL L
Sbjct: 234 VELSSKNVELAL 245
>UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like,
putative; n=5; Oligohymenophorea|Rep: Proteasome subunit
alpha type 7-like, putative - Tetrahymena thermophila
SB210
Length = 242
Score = 97.1 bits (231), Expect = 4e-19
Identities = 57/190 (30%), Positives = 90/190 (47%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA AV IG+RG D +V VEK T+ L E +++ +D+ + +GL
Sbjct: 18 QVEYAMAAVNQGLCSIGIRGTDCIVMGVEKNPTTILQETRTIRKVQRLDDATCICYSGLT 77
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
DAR + A+ E +Y Y VP+ Y+ ++ YT S RP+G S ++G +
Sbjct: 78 PDARILTNIAKVECQSYSLNYDDRVPINYIARYIASVQQKYTQKSGARPFGISTLVGGFD 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
P+++ DPSG + A+GK ++ +EK + +E E A + L
Sbjct: 138 SKGQPRLFQTDPSGACTEWKAVALGKHRKTVMENLEKNYQEEYLAEEKCLELACRVLLEV 197
Query: 214 DELKDKQFEL 185
+ K EL
Sbjct: 198 VQSGCKNIEL 207
>UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 283
Score = 77.4 bits (182), Expect(2) = 5e-19
Identities = 41/127 (32%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA AV T +G++ +G+V A EK +S L +P + +I + ++GM AG+
Sbjct: 20 QIEYALNAVNQGVTALGIKATNGIVLATEKKSSSPLTDPSSLSKISLVTPNIGMVYAGMG 79
Query: 574 SDARQIVETARSEA-SNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
D R +V+ AR + S Y+ Y P + L + V+ + T VRPYG S+++ W
Sbjct: 80 PDYRVLVDKARKVSHSGYKRIYNEYPPTRILVQDVARVVQEATQSGGVRPYGVSLLIAGW 139
Query: 397 TDYEGPQ 377
+ P+
Sbjct: 140 DEGIPPE 146
Score = 39.9 bits (89), Expect(2) = 5e-19
Identities = 19/49 (38%), Positives = 29/49 (59%)
Frame = -2
Query: 385 GPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
GP +Y +DPSG F + A+GK+ +AKT +EK L +++ V A
Sbjct: 177 GPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYTEGLELEDAVHIA 225
>UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 232
Score = 95.9 bits (228), Expect = 1e-18
Identities = 50/172 (29%), Positives = 94/172 (54%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+E A KAV G +G++ K+G V A E +S L E N ++ I+++VG+ +G+
Sbjct: 19 QIESALKAVSLGGQCVGVKAKNGAVIACESKPSSPLVEKVTNLKVQKINDNVGIVYSGVN 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D I+++ R + Y + G +P + + + + M YT VRP+G S+++ W
Sbjct: 79 TDFHVILKSLRKASIKYSLRLGVEMPTREVVKHAAHKMQYYTQIGGVRPFGVSLLIIGWE 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
+ GP ++ +DPSG +++ A+GK ++T +E+ D +V + + A
Sbjct: 139 EL-GPTLWQVDPSGTFWAWKATALGKRSDGSRTFLERRYSEDQSVDDAIHTA 189
>UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like;
n=116; Eukaryota|Rep: Proteasome subunit alpha
type-7-like - Homo sapiens (Human)
Length = 256
Score = 95.1 bits (226), Expect = 2e-18
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 6/163 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVA--- 584
QVEYA +AV+ T +G+RG + VV VEK +KL + ++I +D+HV MA A
Sbjct: 20 QVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALDDHVCMAFAVLT 79
Query: 583 ---GLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSV 413
GL +DAR ++ AR E +++ PV ++Y+ ++ YT + RP+G S
Sbjct: 80 IFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISA 139
Query: 412 VMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
++ + D ++Y DPSG ++ A+G++ + + +EK
Sbjct: 140 LIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEK 182
>UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia
intestinalis|Rep: GLP_387_56144_56881 - Giardia lamblia
ATCC 50803
Length = 245
Score = 93.9 bits (223), Expect = 4e-18
Identities = 56/178 (31%), Positives = 99/178 (55%), Gaps = 2/178 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA K+V S T + +R G+VFAVE+ +S L +RI H+D+H VAG
Sbjct: 21 QIEYALKSVTLSPTALAIRTHTGIVFAVERRTSSPLRLQTRFERIMHVDDHAMACVAGHA 80
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVS-MYMH-AYTLYSAVRPYGCSVVMGT 401
SD++ ++++AR+EA ++R Y VPL+ L+E +S ++++ RP+GCS+++G
Sbjct: 81 SDSKLLLQSARTEAQSHRFLYDEFVPLQALSESLSEVFINFGRGKKKLGRPFGCSLLIG- 139
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
D P+++ +PSG ++G A+ ++ D+T+ + A I+
Sbjct: 140 GLDGSTPRLFCAEPSGSVTEAMARSLGAGSTTAQQTLQDSYRDDMTLDDAKLLALEIL 197
>UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9;
Bilateria|Rep: Proteasome subunit alpha type-6 -
Caenorhabditis elegans
Length = 246
Score = 93.9 bits (223), Expect = 4e-18
Identities = 57/202 (28%), Positives = 110/202 (54%), Gaps = 4/202 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KA+ ++ T + ++G D V AV+K + L ++ I + VG G+
Sbjct: 24 QVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSLIVADTVTSVYQISQSVGCCAIGM 83
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
I DA+ ++ A+ EA++++ + G +P + L ++++ YT + +R GC+++ ++
Sbjct: 84 IPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMADLNQYYTQNAEMRSLGCALLFISY 143
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARIIY 224
D +GP++Y +DP+G G +VG + A + +EK K +LT E + A +
Sbjct: 144 DDEKGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFLEKKIKKKSELTSTEAIELAIEALQ 203
Query: 223 L-VHDELKDKQFELELSWVSKD 161
+ +++ K +LE+ V+KD
Sbjct: 204 TSLGIDVRSK--DLEVVVVTKD 223
>UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome
(prosome macropain) subunit alpha type 4; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Proteasome (prosome macropain) subunit alpha type 4 -
Strongylocentrotus purpuratus
Length = 257
Score = 93.5 bits (222), Expect = 5e-18
Identities = 63/238 (26%), Positives = 115/238 (48%), Gaps = 8/238 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGA-NKRIFHIDEHVGMAVAGL 578
QVEYA +A+ ++GT +G+ DGV+ A E+ T KL + + +I+ ++ + +V+G+
Sbjct: 20 QVEYAMEAIGHAGTSLGILASDGVLLAAERRNTHKLLDDVVFSDKIYKLNSDMACSVSGI 79
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
SDA + R Y QY +P + L + YT RP+G S++ W
Sbjct: 80 TSDANVLTSELRLAGQRYFLQYQENIPNEQLVSTLCDIKQFYTQAGGKRPFGVSILYMGW 139
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEI-EKLKLGDLTVKELVREAARIIYL 221
+ G Q+Y DPSG + +G AA + + ++ K GD +K + A +++
Sbjct: 140 DKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQEYKEGDTDLKGALALAVKVLSK 199
Query: 220 VHDELKDKQFELEL-SWVSKDTKGRHELVPRE-----LATEAENQAKQALADIEDSDE 65
D K ++E+ S +D K + ++P E + E +AK+ A ++ ++
Sbjct: 200 TLDMTKVTPEKIEIASLTREDGKTKIRILPVEELQKLIKEHEEREAKEEAAKKKEKEK 257
>UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1;
Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit,
putative - Trypanosoma cruzi
Length = 179
Score = 92.3 bits (219), Expect = 1e-17
Identities = 49/163 (30%), Positives = 86/163 (52%)
Frame = -2
Query: 628 KRIFHIDEHVGMAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYT 449
+++F +D+HVG +G+ D R +V+ AR YR Y P+P+ L ++S +T
Sbjct: 9 QKVFVLDDHVGCTYSGIGPDCRVLVDAARKACQKYRLTYHEPMPVSQLVRQISSLYQEFT 68
Query: 448 LYSAVRPYGCSVVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGD 269
VRP+GCS+++ D +G +Y +DPSG +++ ++GK AKT +EK +
Sbjct: 69 QSGGVRPFGCSLLV-AGADSQGNHLYQVDPSGTFWAWKATSIGKGSTDAKTFLEKRYTNE 127
Query: 268 LTVKELVREAARIIYLVHDELKDKQFELELSWVSKDTKGRHEL 140
+ +++ V A L E D E + V + ++G+ EL
Sbjct: 128 MEIEDAVHTA----LLTLKEGFDGTMTAENTQVGRVSEGKFEL 166
>UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_32,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 249
Score = 92.3 bits (219), Expect = 1e-17
Identities = 54/201 (26%), Positives = 103/201 (51%), Gaps = 1/201 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGL 578
QVEYA +A+ +G+ +G+ +G++ A EK S L E + ++I+ ID H+ V+G
Sbjct: 20 QVEYAIEAINQTGSALGVLTNEGMILATEKQEVSHLLEHSKHSEKIYPIDRHIFSVVSGH 79
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
+DA ++ AR A+N+R Q+ + L+ L + Y T RP+G + + +
Sbjct: 80 TADANILINYAREAAANHRYQFQDNIALEQLIINICDYKQNKTQVGGQRPFGTAFLFAGY 139
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
G Q++ DPSG + A+GK AA + +++ +LT+++ + A + +
Sbjct: 140 DKKNGFQLFSTDPSGNYAGWKATAIGKNNLAANSYLKQDYKENLTLEQGLDIAIKALVKT 199
Query: 217 HDELKDKQFELELSWVSKDTK 155
D + ++E+ +S+ K
Sbjct: 200 MDTSSPQPSKIEIVVISQQGK 220
>UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain
CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep:
Yarrowia lipolytica chromosome C of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 289
Score = 92.3 bits (219), Expect = 1e-17
Identities = 65/205 (31%), Positives = 103/205 (50%), Gaps = 6/205 (2%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +A++ V+GL K V K +L K+I +D H+G+A+AGL
Sbjct: 20 QVEYALEAIKQGSAVVGLVSKTHAVVVALKRNAEEL--GSYQKKIIKVDNHLGVALAGLA 77
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
DAR + R +A + + Y P+ + ++ T RPYG +++
Sbjct: 78 PDARVLSNFLRQQAMSSQMVYKRPLAVSRAVYAIADKAQGNTQQYGRRPYGVGLLI-IGH 136
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKL--KLGDLTVKELVREAARIIYL 221
D GP +Y PSG + Y G A+G QAA+T +EK DL+++EL+ E +
Sbjct: 137 DEAGPHLYEFLPSGSALEYRGAAIGARSQAARTYLEKKFDTFPDLSLEELIVEG---LNA 193
Query: 220 VHDEL-KDKQFELE---LSWVSKDT 158
+ D L +DK+ L+ +++V KDT
Sbjct: 194 LRDTLAQDKELTLKNTSIAYVGKDT 218
>UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=2; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 238
Score = 90.2 bits (214), Expect = 5e-17
Identities = 48/170 (28%), Positives = 89/170 (52%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYAA A N TV+ ++ +V A+EK KL + ++ + +D+H+ A GL
Sbjct: 18 QIEYAAAAAHNGTTVLAIQAPGIIVAAIEKRDMMKLQKQDSSNNMCLLDKHILCAFTGLP 77
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR +VE A+ EA +YR + +P++ + ++ YT VRP+G + ++ +
Sbjct: 78 ADARVLVEKAQFEAQSYRLTFEDAIPIENIARYIATVQLTYTQSGGVRPFGVTTLICGFD 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVR 245
+ P +Y PSG+ + +G+ + IEK + +L+ ++ R
Sbjct: 138 PLDKPHIYETLPSGILSEWKARGIGRFGHPVQEYIEKYYVDNLSEDDVKR 187
>UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1;
Babesia bovis|Rep: Proteasome subunit alpha type 1 -
Babesia bovis
Length = 257
Score = 89.4 bits (212), Expect = 8e-17
Identities = 62/219 (28%), Positives = 108/219 (49%), Gaps = 2/219 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ +G++ + +V + +SKL E +IF I EH+ + ++G+
Sbjct: 21 QVEYAMEAVKQGTCCVGIKSQTHIVLCAVRRKSSKLAE--YQDKIFCIGEHIAVVMSGIT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SDA+ IV R+E N + YG + L ++ A T S+ RP+G +++ +
Sbjct: 79 SDAKMIVNYMRNECLNNKFLYGCDITATKLVSLIAQKSQANTQTSSKRPFGVGLLVAGYD 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARIIYL 221
D G +Y PSG Y A G Q+AKT +E+ + + L+ A + + +
Sbjct: 139 DRTGLHLYETCPSGNVVEYNATAFGARCQSAKTYLERKIANFEECNIDSLIYHAVKAVKM 198
Query: 220 VHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQ 104
D +F++++ V+ G+ +P +L T AE Q
Sbjct: 199 TIP--SDGEFDVDM--VTVCILGKD--MPFKLLTTAETQ 231
>UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1;
Staphylothermus marinus F1|Rep: 20S proteasome, A and B
subunits - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 213
Score = 89.4 bits (212), Expect = 8e-17
Identities = 60/165 (36%), Positives = 87/165 (52%), Gaps = 1/165 (0%)
Frame = -2
Query: 718 GTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFH-IDEHVGMAVAGLISDARQIVETAR 542
GTV+G++ +GVV A EK +T Y N R H I +HVG+ AGL+ DA+ I+ R
Sbjct: 18 GTVLGIKAVNGVVIAGEKRLTYDGYVLSKNTRKVHPITKHVGIGFAGLVGDAQFIIRALR 77
Query: 541 SEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLD 362
EA NY Q G + ++ L + +S+ +++Y L P VV+G + D +GPQ+Y+LD
Sbjct: 78 MEAENYELQLGREIRVRGLAKILSLILYSYKL----APLMTEVVVGGF-DEKGPQIYVLD 132
Query: 361 PSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
P G A+G A IEK D+ V E + A I
Sbjct: 133 PVGSLIEDKYVALGSGGPIALGIIEKEYREDIDVDEAEKLAVSAI 177
>UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 266
Score = 89.0 bits (211), Expect = 1e-16
Identities = 47/125 (37%), Positives = 73/125 (58%), Gaps = 1/125 (0%)
Frame = -2
Query: 709 IGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARSEAS 530
+G+RGKD VV VEK +KL E ++I +D+HV MA AGL +DAR ++ AR E
Sbjct: 6 VGVRGKDLVVLGVEKKSVAKLQEERTVRKICVLDDHVCMAFAGLTADARILINRARIECQ 65
Query: 529 NYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEG-PQMYMLDPSG 353
++R PV ++Y+ ++ YT + RP+G S ++ DY+G P++Y DP+G
Sbjct: 66 SHRLTVEDPVTVEYITRFMAQLKQRYTQSNGRRPFGLSTLI-VGFDYDGSPRLYQTDPAG 124
Query: 352 VSFSY 338
S+
Sbjct: 125 TYHSW 129
Score = 38.7 bits (86), Expect = 0.15
Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = -2
Query: 454 YTLYSAVRPYGCSVVMGTWTDYEG-PQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
YT + RP+G S ++ + DY+G P++Y DP+G S+ A+G++ + + +EK
Sbjct: 132 YTQSNGRRPFGLSTLIVGF-DYDGSPRLYQTDPAGTYHSWKANAIGRSAKTVREFLEK 188
>UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77;
Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1
- Homo sapiens (Human)
Length = 263
Score = 88.2 bits (209), Expect = 2e-16
Identities = 51/178 (28%), Positives = 87/178 (48%), Gaps = 2/178 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA +AV+ +GL+ K V K S+L K+I H+D H+G+++AGL
Sbjct: 21 QIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKILHVDNHIGISIAGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+DAR + R E + R + P+P+ L + T RPYG +++ +
Sbjct: 79 ADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYD 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARII 227
D GP ++ PS F ++G Q+A+T +E+ + + + ELV+ R +
Sbjct: 139 DM-GPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRAL 195
>UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 233
Score = 87.8 bits (208), Expect = 3e-16
Identities = 55/178 (30%), Positives = 93/178 (52%), Gaps = 2/178 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVE A KAV+ +GL+ K V A ++ S +IF ID+H+G+A++GL
Sbjct: 21 QVENAMKAVQQGMPTVGLKSKTHAVIA--GVMHSPSEFSSHQPKIFKIDQHIGVAISGLT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D R + + R+E ++ +G+ + + L + V++ T RPYG ++M
Sbjct: 79 ADGRGLCKFLRNECLHHTFCFGTEIRVADLADTVALQSQKKTSKVGKRPYGVGLLM-IGA 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARII 227
+GP+++ PSG + Y A+G+ QAAKT +E + D T +L+R A R +
Sbjct: 138 GVDGPRLFETCPSGQHWEYNAQAIGRRAQAAKTYLETNLNEFPDCTRDQLIRHALRAL 195
>UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2;
Trichomonas vaginalis|Rep: Proteasome subunit alpha type
- Trichomonas vaginalis G3
Length = 251
Score = 84.2 bits (199), Expect = 3e-15
Identities = 59/221 (26%), Positives = 111/221 (50%), Gaps = 8/221 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ + + + +GV+FAVEK ++S+L + ++++ ID+HVG+ +AGL
Sbjct: 23 QVEYAIEAVKLGSSAVAILCPEGVIFAVEKRLSSQLLIASSVEKVYAIDDHVGVVMAGLA 82
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTL-------YSAVRPYGCS 416
+D R +VE R EA N+R + P+ +K + + V A+ RP+G +
Sbjct: 83 ADGRTMVEHMRVEAQNHRFSFDEPIGIKAVTQSVCDLALAFGEGRRKKGDGQMSRPFGTA 142
Query: 415 VVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA- 239
+++ + ++ DPSG A+G + A+ + L +T+ E A
Sbjct: 143 LLV-AGIENGKCHLFHTDPSGTYTECRARAIGGGSEGAEALLRDLYKDGMTLHEAEDLAL 201
Query: 238 ARIIYLVHDELKDKQFELELSWVSKDTKGRHELVPRELATE 116
+ + ++ ++L + E+ + VS G+ E+ E E
Sbjct: 202 STLRQVIQEKLNENNVEVACARVS---TGKFEIYTSEQRQE 239
>UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit,
threonine peptidase; n=1; Trichomonas vaginalis G3|Rep:
Family T1, proteasome alpha subunit, threonine peptidase
- Trichomonas vaginalis G3
Length = 241
Score = 80.2 bits (189), Expect = 5e-14
Identities = 52/173 (30%), Positives = 87/173 (50%), Gaps = 2/173 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEY+ KAV+ + T + ++ K+ V AV+K ++ KL +P ++ I ++VG + GL
Sbjct: 20 QVEYSFKAVKQAEVTAVAVKSKNAVCVAVQKKVSDKLIDPSTVTHMYRITDNVGACLVGL 79
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVM-GT 401
SD IV RS A+N+ + G +P+ L + +S + VRP S ++ G
Sbjct: 80 PSDVNFIVMLLRSFANNFEYKQGFSIPVSILAQMLSERHQLESQLVYVRPSAVSAILFGL 139
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVRE 242
+ +Y ++PSG S + A G + A + +EK K+ D E E
Sbjct: 140 DGPSDSFALYKIEPSGYSNGFRAVACGVKEIEAMSALEK-KMEDFETPEATAE 191
>UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative;
n=2; Theileria|Rep: Proteasome subunit alpha type 1,
putative - Theileria parva
Length = 252
Score = 79.8 bits (188), Expect = 7e-14
Identities = 45/157 (28%), Positives = 81/157 (51%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA ++V+ +G++ +V K SKL + +++ + E++G+A++G+
Sbjct: 21 QVEYAMESVKQGTCCVGIKSNTHLVLCALKRKISKLAQ--VQDKLYKVGEYIGVAMSGIT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SDA+ I+ R+E + R YG + L VS A T S+ RP+G +++ +
Sbjct: 79 SDAKMIISYMRNECLSNRFLYGCDITASQLVSLVSEKSQANTQVSSKRPFGVGLLVAGYD 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
+ G ++ PSG + A G Q+AKT +E+
Sbjct: 139 ETTGLHLFETCPSGNVVEFNATAFGARCQSAKTYLER 175
>UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza
sativa|Rep: Proteasome subunit alpha type - Oryza sativa
subsp. japonica (Rice)
Length = 253
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/197 (26%), Positives = 101/197 (51%), Gaps = 7/197 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
Q++YA AV+ +G T +G+RG D V + KL++P +F I + +G+ G+
Sbjct: 38 QLDYAFNAVKLAGITSVGVRGDDSVYVLTHRK-EDKLHDPTTITNLFAITDRIGLLATGM 96
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYG-CSVVMGT 401
D R I + AR+ A+ +R ++G + L + ++ T ++ +RPYG S++ G
Sbjct: 97 PGDGRAIAQEARNAAAEFRFKWGYKMSPCMLAQWIADRAQIRTQHAQIRPYGVVSMIFGI 156
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVG-KAKQAAKTEIEKLK----LGDLTVKELVREAA 236
+ P+++ DP+G F++ + G K K+ E++K L T K L + A
Sbjct: 157 DEEKGTPELFTCDPAGQFFAHKATSAGPKEKEVMNFLEERMKSKPSLSSGTTKGLAKSAL 216
Query: 235 RIIYLVHDELKDKQFEL 185
+ +++ + ++FEL
Sbjct: 217 K--HVLEGDFYAREFEL 231
>UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8;
Trypanosomatidae|Rep: Proteasome subunit alpha type-1 -
Trypanosoma brucei brucei
Length = 266
Score = 78.6 bits (185), Expect = 2e-13
Identities = 50/163 (30%), Positives = 85/163 (52%), Gaps = 6/163 (3%)
Frame = -2
Query: 754 QVEYAAKAVENSGTV-IGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA KAV +G + + +R KD V+ + + KL P +++++++ G+ + G
Sbjct: 21 QVEYAFKAVTYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPETITSLYNVNDNTGVCITGR 80
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYG--CSVVMG 404
D + +V+ AR+EAS Y+ +YG P+ + L + T + +R G + V
Sbjct: 81 APDGKALVQKARNEASEYKYRYGMPMLVSVLAKPWQDMAQVRTQQAGMRLMGTIMTFVGM 140
Query: 403 TWTDYEG---PQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
D +G PQ+Y +DP+G + CAVGK + A +EK
Sbjct: 141 EQNDEDGAWIPQIYCVDPAG-GAAVHACAVGKKQIEACAFLEK 182
>UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vitis
vinifera|Rep: Proteasome subunit alpha type - Vitis
vinifera (Grape)
Length = 219
Score = 78.2 bits (184), Expect = 2e-13
Identities = 35/95 (36%), Positives = 58/95 (61%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV +G+RG D +V VEK T+KL + ++I ++D+H+ +A AGL
Sbjct: 19 QVEYALEAVRKGNAAVGVRGTDTIVLGVEKKSTAKLQDSRTVRKIVNLDDHIALACAGLK 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVS 470
+DAR ++ AR E ++R PV ++Y+ ++
Sbjct: 79 ADARVLINRARIECQSHRLTVEDPVTVEYITRYIA 113
>UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp -
Ashbya gossypii (Yeast) (Eremothecium gossypii)
Length = 306
Score = 77.8 bits (183), Expect = 3e-13
Identities = 53/201 (26%), Positives = 91/201 (45%), Gaps = 3/201 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +A++ +GLR VV K +L K+I D+H+G+++AGL
Sbjct: 94 QVEYALEAIKQGSATVGLRSNKYVVLVALKRNADEL--SSYQKKIIKCDDHMGLSLAGLA 151
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
DAR + R + + + Y + + + +S T RPYG +++ +
Sbjct: 152 PDARVLSNFLRQQCNYSQLVYARDLSVVKAGQLLSDKAQKNTQSYGGRPYGVGLLLAGY- 210
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D G + PSG + +G A+G Q AKT +E++ L +++ + +
Sbjct: 211 DNSGAHLLEFQPSGNTLELYGAAIGARSQGAKTYLERVMEEYLEIEDADALIKHGVEALK 270
Query: 214 DELKDKQF---ELELSWVSKD 161
LKD+ L ++ V KD
Sbjct: 271 HSLKDETLSTKNLSIAIVGKD 291
>UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4;
Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN -
Encephalitozoon cuniculi
Length = 232
Score = 75.8 bits (178), Expect = 1e-12
Identities = 51/163 (31%), Positives = 84/163 (51%), Gaps = 7/163 (4%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA KA+ T IG+R K+ V+ EK I S L P + + + I +H+ + +G+
Sbjct: 19 QIEYAMKAMNLGTTTIGVRTKEFVILCSEKKILSTLQNPKSVVKHYKIYDHIVLGFSGIS 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVP----LKYLNE---RVSMYMHAYTLYSAVRPYGCS 416
D + IV+ +R ++ YG + LKYL+ R A ++ RP+G S
Sbjct: 79 GDTKTIVKRSRDFCISHTHMYGENISVERLLKYLSSLSLRFGEEDEAKMIFR--RPFGVS 136
Query: 415 VVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIE 287
+++ + D E P++Y LDPSG SY A+G + + +E
Sbjct: 137 LIIAGF-DTE-PRLYSLDPSGSYISYKAKAIGSGHEVVEGILE 177
>UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1;
Guillardia theta|Rep: Similar to proteasome A-type
submit - Guillardia theta (Cryptomonas phi)
Length = 233
Score = 75.4 bits (177), Expect = 1e-12
Identities = 45/171 (26%), Positives = 91/171 (53%), Gaps = 1/171 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA+KAV S TVI ++G + ++ + K ++F I++++ ++ +GL
Sbjct: 17 QIEYASKAVLQSNTVISVKGNNLLLTLTLDISNKKNIFTQIEPKVFIINKYIILSASGLK 76
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSV-VMGTW 398
SD ++ ARS +++ +YG + L++ +S ++ +T S RP G S+ ++G
Sbjct: 77 SDIIIVISKARSICRDFQHKYGHQISTASLSKDLSSFLQNFTSSSGFRPLGVSLNILG-- 134
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVR 245
D +GP+++ ++ SG ++GK+ + K I +L K L++
Sbjct: 135 IDKDGPELFEINTSGEINDVNFSSIGKSSKDIKEYIRARWCSNLETKTLLK 185
>UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome
(prosome, macropain) subunit, alpha type, 8 isoform 2;
n=1; Macaca mulatta|Rep: PREDICTED: similar to
proteasome (prosome, macropain) subunit, alpha type, 8
isoform 2 - Macaca mulatta
Length = 261
Score = 74.9 bits (176), Expect = 2e-12
Identities = 36/95 (37%), Positives = 58/95 (61%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ T +G+RG + VV VEK +KL + ++I +D+HV MA AGL
Sbjct: 20 QVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICALDDHVCMAFAGLT 79
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVS 470
+DAR ++ AR E +++ PV ++Y+ ++
Sbjct: 80 ADARVVINRARVECQSHKLTVEDPVTVEYITRFIA 114
>UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE
SUBUNIT C9 - Encephalitozoon cuniculi
Length = 232
Score = 74.5 bits (175), Expect = 3e-12
Identities = 60/203 (29%), Positives = 96/203 (47%), Gaps = 3/203 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVF-AVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVE+A K V +GT+IG DGVV V K T+ G ++I+ + + + + GL
Sbjct: 19 QVEFAIKNVSRAGTIIGYVCSDGVVLMGVNKEPTN-----GPMEKIYQLSDSIYCVLCGL 73
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
DA ++ AR +A ++G PL L + V A+T Y+ RP+G S +
Sbjct: 74 FGDAMELKRYARIKAQEVLERFGVECPLTTLCKFVGQRKQAFTQYAGTRPFGVSFLYAGV 133
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK-LKLGDLTVKELVREAARIIYL 221
D + M DPSG S + G G+ ++A ++ ++ +K E R++
Sbjct: 134 IDGKYALM-STDPSGTSNRWKGMCYGENEEAINRGLKNDFPEDEMDMKTATVEILRLLGK 192
Query: 220 VHDELKDKQFE-LELSWVSKDTK 155
EL K+ + LE+ SKD K
Sbjct: 193 AR-ELGPKEADRLEILHFSKDCK 214
>UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia
intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia
ATCC 50803
Length = 247
Score = 72.9 bits (171), Expect = 8e-12
Identities = 44/147 (29%), Positives = 73/147 (49%), Gaps = 2/147 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
QVEYA +AV+ SG + + +R DGVV + +L + N I I+E + G
Sbjct: 22 QVEYAFRAVKTSGLSHVAIRCLDGVVLVSQLQSADRLVDTANNTFIHEINETSACMICGR 81
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
I+D R++++ RSEA ++ ++ L R++ YT + RP+G V W
Sbjct: 82 IADGRRVIDRVRSEAVDFFRKWNYQPTADILCTRLADINQIYTQEAWQRPFGNIAVFAGW 141
Query: 397 -TDYEGPQMYMLDPSGVSFSYFGCAVG 320
+ + ++ DP+G + YF AVG
Sbjct: 142 DPEQDRSLLFKTDPAGTNTGYFAIAVG 168
>UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3;
Piroplasmida|Rep: Proteasome subunit alpha type -
Theileria annulata
Length = 276
Score = 72.9 bits (171), Expect = 8e-12
Identities = 48/165 (29%), Positives = 82/165 (49%), Gaps = 8/165 (4%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAV---EKLITSK-----LYEPGANKRIFHIDEHV 599
Q+EYA KAV+N + GL KD AV +KL + L + + ++HI + +
Sbjct: 24 QLEYALKAVKNCN-LTGLAIKDDSAIAVVAQKKLPAQQGNQDVLLDTSSVTSLYHITDEI 82
Query: 598 GMAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGC 419
+ GL D I+ AR A +Y +YG +P L +++S YT ++ +R + C
Sbjct: 83 FALLVGLPGDCLSILYKARQVALDYSYKYGINIPASVLCQKISDLNQVYTQHAYMRLHAC 142
Query: 418 SVVMGTWTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
+ ++ + GP++Y D SG Y C +G +Q ++ +EK
Sbjct: 143 TGLILSIEPDVGPKIYKFDSSGWFAGYKACGIGAKEQESENALEK 187
>UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative;
n=5; Plasmodium|Rep: Proteosome subunit alpha type 1,
putative - Plasmodium vivax
Length = 269
Score = 72.9 bits (171), Expect = 8e-12
Identities = 41/157 (26%), Positives = 85/157 (54%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +A++ + ++ KD VV K SKL +++F ID+++G+ ++G+
Sbjct: 21 QVEYANEAIKQGTCAVAIKSKDFVVVCGLKKRISKL--SFHQEKLFKIDDYIGVTMSGIT 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
SDA+ + + R+E +++ + + ++ L ++V+ T S+ R +G +++ +
Sbjct: 79 SDAKVLTKYMRNECLSHKFLFDENMNIEKLVKKVADKYQQNTQRSSRRAFGVGLIIAGY- 137
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
++ P ++ P+G F Y + G A+KT +EK
Sbjct: 138 -FKEPYIFETKPNGSYFEYIALSFGARSHASKTYLEK 173
>UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia
theta|Rep: 26S proteasome SU - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 72.5 bits (170), Expect = 1e-11
Identities = 50/189 (26%), Positives = 92/189 (48%), Gaps = 1/189 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFA-VEKLITSKLYEPGANKRIFHIDEHVGMAVAGL 578
Q+E+A + ++ S + IG+ + G++FA +EK E F +++++ +G
Sbjct: 14 QLEFALELIDKSNSAIGIIYEKGILFATMEK--NKHNSEKEYQNFTFALEKNIICIASGN 71
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
I DA I+ +S A Y+ + VP++ + +S MH T RP G S ++G W
Sbjct: 72 IPDANTILFYLKSFADEYKLMFQETVPIEKIVGYLSDIMHKPTQMIYQRPLGVSFIIGGW 131
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
++ G Q++ +DPSG + ++G +T IE+ + +KE + I+ L
Sbjct: 132 DEFRGFQLFKIDPSGNFSGWRATSIGFNNILNQTLIEENYHNKINLKESI---GIIVKLY 188
Query: 217 HDELKDKQF 191
+ L D F
Sbjct: 189 YKNLNDYNF 197
>UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2;
Ostreococcus|Rep: Proteasome subunit alpha type -
Ostreococcus lucimarinus CCE9901
Length = 236
Score = 72.5 bits (170), Expect = 1e-11
Identities = 55/178 (30%), Positives = 85/178 (47%), Gaps = 2/178 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
QVEYA +AV+ TV+ K V A K SKL ++IF I+ VG+AV+GL
Sbjct: 21 QVEYAMEAVKQGSTVVACGNKKCAVLAALKRKQSKL--SSMQEKIFAINTRVGVAVSGLS 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D ++V+ R E++ YG L S + S+ RP G +V+ +
Sbjct: 79 TDGAKLVKLLREESTREEFVYGRSACPGRLAAAASKSLQISMRKSSGRPCGVGLVLVGSS 138
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK--LKLGDLTVKELVREAARII 227
+ G Q++ PSG A+G Q+A+T +EK L +V E++ A R +
Sbjct: 139 EQLGCQIFQTCPSGEVHQMSCTAIGGRSQSARTYLEKNMEALETASVDEMIMIALRAL 196
>UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 204
Score = 70.1 bits (164), Expect = 5e-11
Identities = 47/166 (28%), Positives = 81/166 (48%), Gaps = 1/166 (0%)
Frame = -2
Query: 718 GTVIGLRGKDGVVFAVEKLITSKLY-EPGANKRIFHIDEHVGMAVAGLISDARQIVETAR 542
GT +G+R DGVV A EK ++ LY + K+++ I + +GMA AGL++D + +
Sbjct: 6 GTTVGIRVSDGVVLAAEKRVSYGLYLMSKSGKKVYRILDKMGMASAGLMADMQTLARIVE 65
Query: 541 SEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLD 362
+E Y + + + +S ++ L+ PY +V+G D EG +Y LD
Sbjct: 66 AEMRLYELDSNISPKVWTVAKLLSYILYERRLF----PYYAEIVVG-GLDEEGSHLYSLD 120
Query: 361 PSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIY 224
P G A+G Q A + +E D+++ E + A + +Y
Sbjct: 121 PIGAIIEDDYVALGSGTQLAISIVESNYKKDMSLDEALSLALKSVY 166
>UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia
intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia
ATCC 50803
Length = 250
Score = 69.3 bits (162), Expect = 9e-11
Identities = 52/232 (22%), Positives = 102/232 (43%), Gaps = 13/232 (5%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+ YA AV+ IG++ +GVV K + L + + ++ +G+ +G
Sbjct: 21 QITYALAAVDGGRLSIGIKCANGVVLMCHKAAENPLVDYPTISLVDNVSPSLGITYSGFS 80
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVV----- 410
+D R ++ R Y +++ +P+ L ++ M YT VRP+GCSV+
Sbjct: 81 ADFRNLLNLGRKSYEQYWNEFQESMPVNMLARDIASTMQEYTQRGGVRPFGCSVLLAGKS 140
Query: 409 MGT--WTDYEGPQ-----MYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKEL 251
M T T+ G + +Y +D SG +++ CA G A+ +EK +++ +
Sbjct: 141 MATEHETEANGSRINPYILYQVDSSGSYYTWKACANGNQSSQARDFLEKRYNESVSISDG 200
Query: 250 VREAARIIY-LVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAK 98
+ ++ V ++ K E+ + + +T G+ L+ + Q K
Sbjct: 201 ILIGLTCLHEYVDGDIDGKTVEIGI--IGDETGGQFRLLAADEINTYARQVK 250
>UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5;
Thermoproteaceae|Rep: Proteasome beta subunit -
Pyrobaculum aerophilum
Length = 202
Score = 68.9 bits (161), Expect = 1e-10
Identities = 45/164 (27%), Positives = 77/164 (46%), Gaps = 1/164 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLY-EPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+ KDGVV A +K +T+ Y ++I+ ID+HV ++G ++D + ++
Sbjct: 3 TTVGIAVKDGVVLATDKRVTAGYYIAHKRGEKIWKIDDHVAATMSGGVADLQSVLSFLTL 62
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
A Y+ +Y P+P+ L YM YS Y ++G + EG +YM+D
Sbjct: 63 RAHEYKIEYKRPIPISALVN----YMSLILFYSRPYIYIVHSIIGGVDEEEGAVLYMVDW 118
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
G A G AK +E D+T+++ V A + +
Sbjct: 119 LGTVTKEKYIATGSGSPYAKGALEVGYREDMTLEDAVDLAIKAV 162
>UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;
n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha
and beta subunit - Cenarchaeum symbiosum
Length = 195
Score = 68.5 bits (160), Expect = 2e-10
Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 1/162 (0%)
Frame = -2
Query: 709 IGLRGKDGVVFAVEKLITSKLYEPGANK-RIFHIDEHVGMAVAGLISDARQIVETARSEA 533
+G++ DGVV + ++ + N +I ID+H G+ +AG ++DA+ IV+ R A
Sbjct: 1 MGIKATDGVVLCADMRASAGYFIANNNTMKIQRIDDHAGLTLAGGVADAQNIVDVLRYHA 60
Query: 532 SNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDPSG 353
S +R + P+P+K L S+ H Y P+ ++MG + D GP +Y +D G
Sbjct: 61 SLHRIRKQGPIPIKSLARLTSLIFHQNRGY----PFMADILMGGF-DAVGPALYNIDMFG 115
Query: 352 VSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
G A +E+ DLT E A R +
Sbjct: 116 SVEEKSYVTTGSGSPVAYGTLEEEYRADLTADEAKGVALRAV 157
>UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4;
Saccharomycetales|Rep: Proteasome component Y7 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 178
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/121 (30%), Positives = 68/121 (56%), Gaps = 2/121 (1%)
Frame = -2
Query: 595 MAVAGLISDARQIVETARSEA-SNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGC 419
M +G+ D R +V+ AR A +NY+ Y P++ + + ++ M T +RP+G
Sbjct: 1 MTYSGMGPDFRVLVDKARKLAQTNYKLIYNEYPPVRIMVQEIAKVMQESTQSGGIRPFGV 60
Query: 418 SVVMGTWTDY-EGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVRE 242
S+++G + +Y + Q+Y +DPSG F + A+GK +AKT +EK +L +++ +
Sbjct: 61 SLLVGGYDEYLDKFQLYQVDPSGSYFPWKATAIGKTSNSAKTFLEKRWNENLQLEDAIHV 120
Query: 241 A 239
A
Sbjct: 121 A 121
>UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillardia
theta|Rep: 26S proteasome SU alpha7 - Guillardia theta
(Cryptomonas phi)
Length = 241
Score = 67.3 bits (157), Expect = 4e-10
Identities = 41/190 (21%), Positives = 90/190 (47%), Gaps = 2/190 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANK--RIFHIDEHVGMAVAG 581
Q+EY++K + S +G++ DG++ + K I S Y + IF ++ ++ M +G
Sbjct: 23 QLEYSSKCINKSNIALGIKCNDGLI--IFKEIDSNQYNNDIIECNMIFCLNHYMAMTSSG 80
Query: 580 LISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGT 401
+ D R + E + +YG + KYL +S H + ++RP C +++G
Sbjct: 81 ITGDFRSLCNRLVDENLIEKYRYGLELNSKYLTHLLSRLFHLNSNSWSLRPLACDIILG- 139
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYL 221
+ DY +++ + G + G A + E+E + +L+ ++++ + + +
Sbjct: 140 FIDYSSLEIFFISNQGSIIKTNNISTGSACELINFELESIFKEELSCRKVILKIIKKLSA 199
Query: 220 VHDELKDKQF 191
+ +L+ K F
Sbjct: 200 LTRDLQSKYF 209
>UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome
endopeptidase complex - Candidatus Nitrosopumilus
maritimus SCM1
Length = 210
Score = 66.9 bits (156), Expect = 5e-10
Identities = 44/164 (26%), Positives = 79/164 (48%), Gaps = 1/164 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGANK-RIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G++ KDGVV + ++ + N +I ID+H G+ +AG ++DA+ IV+ R
Sbjct: 14 TTVGIKAKDGVVLCADMRASAGYFIANNNTMKIQKIDDHAGLTLAGGVADAQNIVDILRY 73
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
++ +R + P+ + L S+ H Y P+ +++G + D EGP ++ +D
Sbjct: 74 HSNLHRVEKHGPISIHSLARLCSLIFHQNRGY----PFMADILVGGY-DAEGPALFNIDM 128
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
G G A +E+ DLTV+E + A R +
Sbjct: 129 FGSVEKKAYVTTGSGSPVAYGLLEEEYREDLTVEEAKKIALRAV 172
>UniRef50_A1RWY6 Cluster: Proteasome endopeptidase complex; n=1;
Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase
complex - Thermofilum pendens (strain Hrk 5)
Length = 200
Score = 66.5 bits (155), Expect = 7e-10
Identities = 48/166 (28%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGANK---RIFHIDEHVGMAVAGLISDARQIVETA 545
T +GL GKD VV A ++ T+ + ANK +I ID H+ +AG + DA+Q+V+
Sbjct: 14 TTVGLVGKDFVVLAADRRATAGYFI--ANKQTWKIVEIDSHIAATIAGTVGDAQQLVDRL 71
Query: 544 RSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYML 365
R EA Y++ G +P+K + S+ + Y RP ++ D +GP ++ +
Sbjct: 72 RVEARYYKTITGDSMPVKSVATLASLILFQY------RPILSVQMLIGGVDSDGPSLFSV 125
Query: 364 DPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
D G A G A + +E DL+++E V A + +
Sbjct: 126 DWLGTVTREKYTATGSGSPYAVSLLEHEYREDLSLEEAVNLAVKAV 171
>UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5;
Thermoproteaceae|Rep: Proteasome, beta subunit -
Pyrobaculum aerophilum
Length = 203
Score = 65.7 bits (153), Expect = 1e-09
Identities = 44/169 (26%), Positives = 81/169 (47%), Gaps = 1/169 (0%)
Frame = -2
Query: 730 VENSGTVIGLRGKDGVVFAVEKLITSKLYE-PGANKRIFHIDEHVGMAVAGLISDARQIV 554
V+ T +G++ KDGVV A EK ++ Y A K++F ID+ + +A AG+I+D + +
Sbjct: 5 VQIGATAVGIKAKDGVVLAAEKRVSYGFYTLSSAGKKVFVIDDKLAIASAGIIADMQTLA 64
Query: 553 ETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQM 374
+ + A Y + + +S+ M + P+ V++G D EGP +
Sbjct: 65 KILKLNAKAYELEMKRKPSTHSMARLLSVIMFS----RRFMPFFAEVLVG-GIDEEGPHL 119
Query: 373 YMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
++DP G A+G + A ++ D+TV+E + A + +
Sbjct: 120 IVMDPLGSLIEDNYAALGTGAKLAVAVLDTGYRPDITVEEAKKLAVQAL 168
>UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1;
Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT
ALPHA-4 - Encephalitozoon cuniculi
Length = 224
Score = 62.1 bits (144), Expect = 1e-08
Identities = 47/166 (28%), Positives = 81/166 (48%), Gaps = 3/166 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEH--VGMAVAG 581
QVEYA +A E V+ + + ++E+ ++L +++F I E + M+ +G
Sbjct: 18 QVEYAQQASEQGSLVVFGVDSEKISVSIERKSGNRLLLE--EEKLFPISESQKIWMSYSG 75
Query: 580 LISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGT 401
DA ++ AR +Y++ G + + L +S Y YT+ RP+G V+
Sbjct: 76 FKPDAYLVMNVARMICFSYKNSTGEDIAIDQLARMLSEYKQRYTVVYHQRPFGVRTVL-- 133
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGC-AVGKAKQAAKTEIEKLKLGDL 266
+ P Y+L+P G +FS F C A+G+ Q +EK + GDL
Sbjct: 134 FGLEPRPVAYVLEPDG-NFSEFFCGAIGQKSQKVCEYLEKGEKGDL 178
>UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5;
Plasmodium|Rep: Proteasome subunit alpha, putative -
Plasmodium falciparum (isolate 3D7)
Length = 284
Score = 60.9 bits (141), Expect = 3e-08
Identities = 49/189 (25%), Positives = 89/189 (47%), Gaps = 31/189 (16%)
Frame = -2
Query: 754 QVEYAAKAVENSG-TVIGLRGKD-GVVFAVEKLITS-----KLYEPGANKRIFHIDEHVG 596
Q+EYA KAV+N+ T +G++G++ V+ + +K+ T KL + I++I + +G
Sbjct: 24 QIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIG 83
Query: 595 MAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCS 416
++ G+ D +V ARSEAS + G V + L + + YT ++ +R + CS
Sbjct: 84 CSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACS 143
Query: 415 -----VVMGTWT-------------------DYEGPQMYMLDPSGVSFSYFGCAVGKAKQ 308
+ M T + P+++ DPSG Y C +G +Q
Sbjct: 144 NIYIYIYMNICTCVFIFLHKCVKCGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQ 203
Query: 307 AAKTEIEKL 281
+ + +E+L
Sbjct: 204 ESISVLERL 212
>UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9;
Euryarchaeota|Rep: Proteasome subunit beta precursor -
Methanococcus jannaschii
Length = 224
Score = 60.9 bits (141), Expect = 3e-08
Identities = 41/161 (25%), Positives = 79/161 (49%), Gaps = 2/161 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +GL D V+ A +K + L K+++ ID+++ M +AG + DA+ IV +
Sbjct: 8 TTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIA 67
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
EA Y+ + G +P +S +H+ ++ P+ +++G + EG +++ LDP
Sbjct: 68 EAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKLFSLDP 123
Query: 358 -SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
G++ A G A +E D++V+E ++ A
Sbjct: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLA 164
>UniRef50_Q2HWA9 Cluster: 20S proteasome, A and B subunits; n=1;
Medicago truncatula|Rep: 20S proteasome, A and B
subunits - Medicago truncatula (Barrel medic)
Length = 336
Score = 60.1 bits (139), Expect = 6e-08
Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 7/183 (3%)
Frame = -2
Query: 736 KAVENSGTVIGLRGKDGVVFAVEKLI---TSKLYEPGANKRIFHIDEHVGMA----VAGL 578
K ++ T IGL+ K+GVV A EK I TS LY PG + I ID ++ +A V G
Sbjct: 131 KQMQLGTTAIGLKFKEGVVLAAEKRITWPTSPLY-PGIVQNIMEIDNNICIAVTVTVTGS 189
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
I++A ++V AR+ A P+ + + +++S Y L + P+ S++ G
Sbjct: 190 IANASKLVGEARTLALANNISRCQPMVVDSMCQKLS-----YELADQIHPFVVSLIAG-- 242
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLV 218
D P +Y DP G A+G + A +E+ DLT+++ A I+ V
Sbjct: 243 HDNNRPSLYYSDPFGSFQQCNAKAIGLRSEGADRSLEEQFNQDLTLEKAETIALSILKQV 302
Query: 217 HDE 209
E
Sbjct: 303 MGE 305
>UniRef50_Q9P996 Cluster: Proteasome subunit beta precursor; n=10;
Euryarchaeota|Rep: Proteasome subunit beta precursor -
Archaeoglobus fulgidus
Length = 213
Score = 59.3 bits (137), Expect = 1e-07
Identities = 47/166 (28%), Positives = 74/166 (44%), Gaps = 2/166 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +GL KDGVV A EK T A K+I+ I + + M AG + DA+ + +
Sbjct: 13 TTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIKI 72
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
EA+ Y + ++ + S +++Y + PY +++G D EG +Y +DP
Sbjct: 73 EANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIG-GIDSEGKSIYSIDP 127
Query: 358 SGVSFSYFG-CAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIY 224
G + A G A +E ++ V E V A R IY
Sbjct: 128 IGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIY 173
>UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum
pernix|Rep: Proteasome beta subunit - Aeropyrum pernix
Length = 203
Score = 58.0 bits (134), Expect = 2e-07
Identities = 39/164 (23%), Positives = 77/164 (46%), Gaps = 1/164 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+R +DGVV A +K ++ + N K+IF I++ +G+A AGL D +V
Sbjct: 7 TALGIRVEDGVVLAADKRMSYGGFILSRNFKKIFVINDRIGIAFAGLYGDMGGLVRIVEG 66
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
+ + G P ++ + + +S +++Y + P+ ++G P++Y+LDP
Sbjct: 67 QMRLASLETGKPATVRNVAKFLSSLLYSYKFF----PFNVEAIVGGIDPGGEPKLYVLDP 122
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
G A G A +E + ++++E + A +
Sbjct: 123 LGSIIEEDYVAAGTGATTAFGLLEHVYKRGMSLEEAKKAAVEAL 166
>UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1;
Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT
C6 - Encephalitozoon cuniculi
Length = 234
Score = 57.6 bits (133), Expect = 3e-07
Identities = 48/173 (27%), Positives = 74/173 (42%), Gaps = 1/173 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFH-IDEHVGMAVAGL 578
Q+EY +AV N V+ + KD +V +K+ KL E A FH + E +A+ GL
Sbjct: 19 QIEYGLEAVNNGLPVVTAKSKDMIVCVSKKIPQDKLEESEATS--FHRVSEKCYVAITGL 76
Query: 577 ISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
D +V+ + A+ +G V L + + SA R + + +
Sbjct: 77 PGDTDYVVKRIKMVANRKAFSFGFEVTPDILCRSFADKVQQLIQSSAERSAAFNASIFGF 136
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
D E P +Y D SG+S+ + A G+ IEK D+ KEL A
Sbjct: 137 -DKERPMIYQTDMSGISYPCYATAAGEKHGKMTKFIEKNYRSDIDDKELFEVA 188
>UniRef50_Q980L4 Cluster: Proteasome subunit; n=4;
Sulfolobaceae|Rep: Proteasome subunit - Sulfolobus
solfataricus
Length = 196
Score = 56.4 bits (130), Expect = 7e-07
Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 1/143 (0%)
Frame = -2
Query: 727 ENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVE 551
E T +GL+ DG+V A E+ ++ Y K+++ I++ + MA AG+ D + +
Sbjct: 3 ELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFL-MAGAGIYGDLQTLTR 61
Query: 550 TARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMY 371
E Y G P+ + + +S+ ++ Y V P+ ++ G D +GPQ+Y
Sbjct: 62 IMNVEIKYYEVSTGKPISVHAAAKLLSVILYQYK----VMPFISEILFGG-VDEKGPQLY 116
Query: 370 MLDPSGVSFSYFGCAVGKAKQAA 302
+LDP G AVG + A
Sbjct: 117 VLDPIGSLIEDNYAAVGSGARIA 139
>UniRef50_Q9NC68 Cluster: 20S proteasome alpha subunit; n=1;
Spraguea lophii|Rep: 20S proteasome alpha subunit -
Spraguea lophii
Length = 99
Score = 56.0 bits (129), Expect = 9e-07
Identities = 32/103 (31%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Frame = -2
Query: 736 KAVENSGTVIGLRGKDGVV-FAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQ 560
+ V+N GT+IG+ DGVV F ++K + YE +++ I + + + G SDA Q
Sbjct: 2 EGVQNGGTIIGITCNDGVVLFGMKKEKSLIKYE-----KLYKISDGIHCCICGNSSDALQ 56
Query: 559 IVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVR 431
++ AR +A+ + ++G P+PL L ++V +TL +R
Sbjct: 57 MIGYARLKAAEFEEEFGIPIPLLTLCKKVGAIKQNFTLGGGLR 99
>UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia
theta|Rep: 26S proteasome IOTA SU - Guillardia theta
(Cryptomonas phi)
Length = 237
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/145 (26%), Positives = 68/145 (46%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA K + S IG++ ++F + K S E + IF +D+ G GL
Sbjct: 18 QIEYAVKKKKGS-ICIGIKNNSFLIFLLYKSQNSSS-ESNESDIIF-LDDKTGCLCNGLA 74
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D + +E ++ NY SQY S + YL++ ++ T YS RP ++++
Sbjct: 75 IDVYEQIEEIKNIFFNYYSQYRSKIQTSYLSKLITFKNQYLTHYSFSRPRSTNLIIFNLD 134
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVG 320
+ G Q++ D +G C++G
Sbjct: 135 NELGGQLFKGDNTGSFILTNECSIG 159
>UniRef50_A5UM14 Cluster: Proteasome, beta subunit; n=1;
Methanobrevibacter smithii ATCC 35061|Rep: Proteasome,
beta subunit - Methanobrevibacter smithii (strain PS /
ATCC 35061 / DSM 861)
Length = 204
Score = 54.8 bits (126), Expect = 2e-06
Identities = 50/197 (25%), Positives = 87/197 (44%), Gaps = 1/197 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+ KDGVVFA E+ + L ++IF I++H+ +AG + DA+ +++ +
Sbjct: 10 TTVGITCKDGVVFASERRASMGNLVAHKVAEKIFKINDHIVTTIAGSVGDAQNLMKIIEA 69
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
E S Y+ + + +K + + A L S P ++G D + P +Y LDP
Sbjct: 70 EVSLYQMRNNDKISVK-----AAASVTANILRSG--PMYVQTLLG-GMDGDKPSLYSLDP 121
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVHDELKDKQFELEL 179
+G + G A +E ++T E + A R I + F
Sbjct: 122 AGGMIEDTYISTGSGSIVAYGVLEDRYHEEITTDEGLEIAVRAIKAASER---DTFSGNG 178
Query: 178 SWVSKDTKGRHELVPRE 128
V+K TK E++ +E
Sbjct: 179 YLVAKVTKDGFEMLDKE 195
>UniRef50_Q4UIA0 Cluster: Proteasome subunit beta type; n=8;
Aconoidasida|Rep: Proteasome subunit beta type -
Theileria annulata
Length = 271
Score = 53.2 bits (122), Expect = 7e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARS 539
T+ G+ G+D VV A + T + N ++ I +++ A AG+ +D + T
Sbjct: 42 TICGVMGRDSVVLAADTRATQGIIVADKNCSKLHKISDNIYCAGAGVAAD---LEHTTLW 98
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
A+N + + +SM +H Y + C++++G + DY GP ++ + P
Sbjct: 99 LANNIELHRLNTKKAPRVQMCISMLVHELFKYQGYKQ--CALILGGF-DYTGPHLFSVSP 155
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
G S S C +G A T +E+ ++V+E A + I
Sbjct: 156 HGSSDSLPFCTMGSGSLNAMTVLEQNYFDGMSVEEATELAVKAI 199
>UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1;
Encephalitozoon cuniculi|Rep: 20S PROTEASOME COMPONENT
C3 - Encephalitozoon cuniculi
Length = 233
Score = 52.4 bits (120), Expect = 1e-05
Identities = 42/158 (26%), Positives = 62/158 (39%), Gaps = 1/158 (0%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q + A +A N IG DG V K + + K +F I + +G +GL
Sbjct: 20 QCDNALRAAVNGSLSIGASAADGAVLMSFKDVPPLVIREEVRK-VFKICDTIGCTYSGLQ 78
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
D R V A Y YG + S + YT S RP+G ++
Sbjct: 79 PDCRIQVNIGCQIAEEYYDVYGRYPDVDVFTAHFSSVVQEYTQKSGYRPFGTLMIFA--G 136
Query: 394 DYEG-PQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
G P++Y +DPSG + CA G A+ +E+
Sbjct: 137 PVRGVPRLYQVDPSGSYQTADVCASGVGYSDARKFVER 174
>UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2;
Desulfurococcales|Rep: Proteasome beta subunit -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 204
Score = 52.0 bits (119), Expect = 2e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 1/155 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+RG VV A EK ++ ++++ I +++G+A+AGL +D + I + R+
Sbjct: 10 TAVGIRGAGYVVLAAEKRVSYGGFIISKTARKVYKITDYLGLALAGLFADLQAISKILRA 69
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
E Y G + ++ + ++ +++Y Y P+ ++G ++Y++DP
Sbjct: 70 EIEYYNIVTGRRISVRAVARLLATILYSYKYY----PFLSETLVGGLEADGTAKLYVMDP 125
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKE 254
G A+G A +E D++V +
Sbjct: 126 LGSLIEDDYAAIGSGAPIAIGILENGYSKDMSVDD 160
>UniRef50_Q8SQS5 Cluster: 20S PROTEASOME ALPHA SUBUNIT; n=1;
Encephalitozoon cuniculi|Rep: 20S PROTEASOME ALPHA
SUBUNIT - Encephalitozoon cuniculi
Length = 239
Score = 48.4 bits (110), Expect = 2e-04
Identities = 42/184 (22%), Positives = 79/184 (42%), Gaps = 2/184 (1%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+++ + E GT +GL+ + V S+L + K++F ID +G+
Sbjct: 30 QLDFIRQTTELGGTAVGLKNRSVGVLIAHNERRSRLAD--IQKKVFSIDRKSLFTFSGIT 87
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D QIV+ ++ G + + E + + T+ R YG S + T
Sbjct: 88 NDGLQIVDYLIDKSVREEVIKGRAIHFLDVFEDLLRDVFERTILDGRRLYGVSGLY--MT 145
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKL--KLGDLTVKELVREAARIIYL 221
+Y+G ++ +P G G +G Q+++T +E + + V+ELVR +
Sbjct: 146 EYDGIRLVEFNPKGHVREVKGMGIGCRAQSSRTVLEAYCEEYEKMGVEELVRIGIMALKN 205
Query: 220 VHDE 209
H E
Sbjct: 206 AHPE 209
>UniRef50_Q9V247 Cluster: PsmB proteasome, subunit beta; n=4;
Thermococcaceae|Rep: PsmB proteasome, subunit beta -
Pyrococcus abyssi
Length = 197
Score = 48.4 bits (110), Expect = 2e-04
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 5/166 (3%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVE-KLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+R KDGV+ A + + + E ++I I + + + AG + D + I +
Sbjct: 8 TTVGIRVKDGVILAADTQASLDHMVETLNIRKIIPITDRIAITTAGSVGDVQMIARILEA 67
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
EA Y+ +G P+ + + +S ++ + PY +++G + D P + LDP
Sbjct: 68 EARYYQFTWGRPMTTRAMANLLSNILNENKWF----PYLVQIIIGGYVD--EPTIANLDP 121
Query: 358 -SGVSFSYFGCAVGKAKQAAKTEIE---KLKLGDLTVKELVREAAR 233
G+ F + A G A +E + LG KEL +A +
Sbjct: 122 LGGLIFDDY-TATGSGTPFAIAILEEGYRKNLGIEKAKELAIKAVK 166
>UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1628
Score = 48.0 bits (109), Expect = 3e-04
Identities = 25/64 (39%), Positives = 36/64 (56%)
Frame = -2
Query: 754 QVEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLI 575
Q+EYA +AV+ + L+ K V K S+L K+I ID HVG+++AGL
Sbjct: 709 QIEYAMEAVKQGSATVALKSKTHAVIVALKRAPSEL--SAHQKKILPIDTHVGVSIAGLT 766
Query: 574 SDAR 563
+DAR
Sbjct: 767 ADAR 770
>UniRef50_Q9HR36 Cluster: Proteasome, subunit alpha; n=7;
Halobacteriaceae|Rep: Proteasome, subunit alpha -
Halobacterium salinarium (Halobacterium halobium)
Length = 255
Score = 47.6 bits (108), Expect = 3e-04
Identities = 36/165 (21%), Positives = 75/165 (45%), Gaps = 2/165 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFA--VEKLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETAR 542
T++GL +DGV+ A + + ++ +++ I + ++++G + A+ + + R
Sbjct: 62 TIVGLTTQDGVLMASDMRASLGGRVISNKNVQKVEEIQPNAALSISGSVGGAQSFIRSLR 121
Query: 541 SEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLD 362
+EA+ Y ++ G + + L+ S + + V G D +G ++ LD
Sbjct: 122 AEANLYEARRGEYMSIDALSTMASNLLRGGPFFRVVPILG-------GVDDDGGHVFSLD 174
Query: 361 PSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
P+G S S A G A +E+ DLT+ + + AA +
Sbjct: 175 PAGSSMSDTYTAQGSGMPYALGVLEQEYSEDLTMADAEQVAAHAV 219
>UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia
theta|Rep: 26S proteasome SU A5 - Guillardia theta
(Cryptomonas phi)
Length = 232
Score = 45.6 bits (103), Expect = 0.001
Identities = 34/138 (24%), Positives = 70/138 (50%), Gaps = 5/138 (3%)
Frame = -2
Query: 751 VEYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANKRIFHIDEHVGMAVAGLIS 572
+EYA +A T G++ KD +F + + K + +++I+ +D++ G V+GLIS
Sbjct: 16 LEYAQEAANLGSTSCGIKTKD-FIFILSERKKKKSLDYLNDQKIYVLDKNKGCCVSGLIS 74
Query: 571 DARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAV-----RPYGCSVVM 407
D+R+I++ R N S ++ + ++ + +Y + V RP G S ++
Sbjct: 75 DSRKIIDNVRIYCENKYFLINSYPSIEECSNLINNLITSYNTNNDVNKISPRPLGTSFLL 134
Query: 406 GTWTDYEGPQMYMLDPSG 353
++ + ++ +DPSG
Sbjct: 135 FGKSN-KKLELIKVDPSG 151
>UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;
Sulfolobaceae|Rep: Proteasome subunit beta precursor -
Sulfolobus solfataricus
Length = 208
Score = 45.6 bits (103), Expect = 0.001
Identities = 36/166 (21%), Positives = 78/166 (46%), Gaps = 2/166 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+R DGV+ A ++ ++ + +++ +I + +G+ AG ++D + I + ++
Sbjct: 16 TTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVLKN 75
Query: 538 -EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLD 362
N ++YG P+ +K + R++ + A + PY +++G + D P+++ LD
Sbjct: 76 IYHYNSITKYG-PISIKGIATRLANVLSATKYF----PYIVQILIGGYDDQ--PRLFNLD 128
Query: 361 PSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIY 224
G A G A +E +T+ E A R ++
Sbjct: 129 YLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVF 174
>UniRef50_Q5B7I7 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 215
Score = 44.4 bits (100), Expect = 0.003
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 11/173 (6%)
Frame = -2
Query: 724 NSGTVIGLRGKDGVVFAVEKLITSKL-----YEPGANKRIFHIDEHVGMAVAGLISDARQ 560
N G +G+ G D + A + T+ YEP D + ++V G +D R
Sbjct: 13 NGGATLGVSGPDFAILAGDTRSTAGYNINTRYEPKVFTIQDARDRSIVISVIGFAADGRA 72
Query: 559 IVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGC-SVVMGTWTDYEG 383
+ E + + Y+ Q+G + L+ +RVS ++ + PY ++V G D +G
Sbjct: 73 LKERLDAIVAMYKYQHGKNIGLRACAQRVSTMLYEKRFF----PYQLQTMVAGIDADGQG 128
Query: 382 PQMYMLDPSGVSFSYFGCAVGKAKQA----AKTEIEKLK-LGDLTVKELVREA 239
+Y DP+G CA G+A ++ +L+ L T ++LVR+A
Sbjct: 129 -AIYYYDPAGCIEKRSHCAAGEASSLMLPFLDSQAPRLQPLSLQTAQQLVRDA 180
>UniRef50_A7DSL9 Cluster: Proteasome endopeptidase complex; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome
endopeptidase complex - Candidatus Nitrosopumilus
maritimus SCM1
Length = 198
Score = 42.7 bits (96), Expect = 0.009
Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+ GVVFA EK I K+ F I VG AGL++D + + +
Sbjct: 9 TAVGITFDGGVVFASEKRIAFGNFLVSKTTKKTFPITPKVGATCAGLVADMQILSLQIAA 68
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
A + + VP + + +S M+ + P V++G D P MY LDP
Sbjct: 69 LAKIRKMELKRDVPPNTVAKMMSNMMYERRYF----PLLTQVIVGGVVDK--PIMYTLDP 122
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
G AVG + A ++ ++T E + A R +
Sbjct: 123 LGSVLPDEYAAVGTGAEMALGVLDPQFKPNMTKDEAIDLAKRAV 166
>UniRef50_Q4R6A8 Cluster: Testis cDNA, clone: QtsA-18608, similar to
human proteasome (prosome, macropain) subunit, alpha
type, 5(PSMA5),; n=1; Macaca fascicularis|Rep: Testis
cDNA, clone: QtsA-18608, similar to human proteasome
(prosome, macropain) subunit, alpha type, 5(PSMA5), -
Macaca fascicularis (Crab eating macaque) (Cynomolgus
monkey)
Length = 117
Score = 42.3 bits (95), Expect = 0.012
Identities = 22/75 (29%), Positives = 43/75 (57%)
Frame = -2
Query: 394 DYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIYLVH 215
D +GPQ++ +DPSG A+G A + A++ ++++ +T+KE ++ + I+ V
Sbjct: 23 DEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVM 82
Query: 214 DELKDKQFELELSWV 170
+E K +EL+ V
Sbjct: 83 EE-KLNATNIELATV 96
>UniRef50_Q8LD27 Cluster: Proteasome subunit beta type-6 precursor;
n=14; Magnoliophyta|Rep: Proteasome subunit beta type-6
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 233
Score = 40.3 bits (90), Expect = 0.050
Identities = 27/122 (22%), Positives = 56/122 (45%), Gaps = 1/122 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPG-ANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T+IG+ GVV + ++ +Y A+ +I + ++V + +G +D++ + + R
Sbjct: 14 TIIGVTYNGGVVLGADSRTSTGMYVANRASDKITQLTDNVYVCRSGSAADSQVVSDYVRY 73
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
+ Q+G P +K VS + Y+ +++G W YEG ++Y +
Sbjct: 74 FLHQHTIQHGQPATVK-----VSANLIRMLAYNNKNMLQTGLIVGGWDKYEGGKIYGIPL 128
Query: 358 SG 353
G
Sbjct: 129 GG 130
>UniRef50_O23370 Cluster: Cell wall protein like; n=15;
Magnoliophyta|Rep: Cell wall protein like - Arabidopsis
thaliana (Mouse-ear cress)
Length = 428
Score = 39.9 bits (89), Expect = 0.066
Identities = 19/39 (48%), Positives = 28/39 (71%), Gaps = 1/39 (2%)
Frame = -2
Query: 694 KDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAG 581
KDGVV EK +TSKL + ++ ++++ ID+HV AVAG
Sbjct: 322 KDGVVLVGEKKVTSKLLQTSSSMEKMYKIDDHVACAVAG 360
Score = 37.5 bits (83), Expect = 0.35
Identities = 20/58 (34%), Positives = 33/58 (56%)
Frame = -2
Query: 400 WTDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
W G Q+YM DPSG + AVG QAA++ +++ D T +E+V+ A +++
Sbjct: 361 WDRNHGFQLYMSDPSGNYGGWQAAAVGANNQAAQSILKQDYKDDATREEVVQLAIKVL 418
>UniRef50_Q22X00 Cluster: Proteasome A-type and B-type family
protein; n=2; Alveolata|Rep: Proteasome A-type and
B-type family protein - Tetrahymena thermophila SB210
Length = 282
Score = 39.9 bits (89), Expect = 0.066
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 4/172 (2%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITS-KLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T++GL KDGVV + T+ + + +I +I ++ AG +D + + + S
Sbjct: 42 TIVGLVYKDGVVLGADTRATAGTIVAEKSCSKIHYIAPNMYCCGAGTAADTQWVTDRLSS 101
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
E R + R+ +++ Y + G +++G + D +GPQ+ +
Sbjct: 102 ELELMRLNTNRQSRIAGAIARLREHLYQYQGH-----VGAHLILGGF-DCQGPQLVSVAA 155
Query: 358 SGVSFSYFGCA-VGKAKQAAKTEIEKLKLGDLTVKELVREAARIIY--LVHD 212
G SFSY A +G AA +E DLT +E + I +VHD
Sbjct: 156 HG-SFSYLPYATMGSGCLAAIATLESRYRDDLTEQEAIDLVTASIESGIVHD 206
>UniRef50_Q98S31 Cluster: Proteasome subunit beta type; n=1;
Guillardia theta|Rep: Proteasome subunit beta type -
Guillardia theta (Cryptomonas phi)
Length = 236
Score = 39.5 bits (88), Expect = 0.088
Identities = 36/152 (23%), Positives = 71/152 (46%), Gaps = 3/152 (1%)
Frame = -2
Query: 730 VENSGT-VIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQI 557
V+ +GT +IG+ K+ +V A + T K+ + K+I I ++G+ AG +D + I
Sbjct: 30 VDKTGTTIIGICIKNHIVLAADTRSTRGKITNDSSCKKIHFIGNNIGICGAGTSADIQNI 89
Query: 556 VETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYT-LYSAVRPYGCSVVMGTWTDYEGP 380
+ + + + L+ + + ++ Y + SA ++++G + DY G
Sbjct: 90 INYLKININFLNLEKLKETNLEECTKIIQNFLFNYKGMISA------ALIIGGF-DYYGL 142
Query: 379 QMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEK 284
+Y + P G F ++G AA T +EK
Sbjct: 143 NLYSIYPDGSMDKNFFISMGSGSFAAMTILEK 174
>UniRef50_Q8SQN7 Cluster: Proteasome subunit beta type; n=1;
Encephalitozoon cuniculi|Rep: Proteasome subunit beta
type - Encephalitozoon cuniculi
Length = 227
Score = 38.7 bits (86), Expect = 0.15
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARS 539
T++G++ K GV+ A + T N +I I + + AG +DA ++ A
Sbjct: 8 TIVGMKYKTGVILAADTRSTQGPVVSDKNCVKIHQITDKIMCCGAGTAADASRVARMASR 67
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
E ++++Y + + + + ++H Y G ++++G D EG +Y + P
Sbjct: 68 ELRLFQNKYLRLPLVSHFRKVCTQHLHKYG-----GGIGAALIVG-GIDSEGCHLYEIHP 121
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIE 287
G S ++G A +E
Sbjct: 122 HGSENSALFVSLGSGSLGAIATLE 145
>UniRef50_Q1ZXN1 Cluster: Proteasome subunit beta type; n=2;
Dictyostelium discoideum|Rep: Proteasome subunit beta
type - Dictyostelium discoideum AX4
Length = 236
Score = 37.1 bits (82), Expect = 0.47
Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = -2
Query: 730 VENSGTVIGLRGKDGVVFAVEKLITSKLYEPGANK--RIFHIDEHVGMAVAGLISDARQI 557
V+N GTV+ + GKD V A + ++ Y K +IF + + +A +G+ +D +
Sbjct: 27 VDNGGTVLAVAGKDYCVIAGDTRMSDGGYGIQTRKYTKIFQLTKKCVLATSGMQADTIAL 86
Query: 556 VETARSEASNYRSQYGSPV 500
+ +S ++ ++G P+
Sbjct: 87 QKRLKSMLESFEKEHGKPM 105
>UniRef50_A2F716 Cluster: Proteasome subunit beta type; n=1;
Trichomonas vaginalis G3|Rep: Proteasome subunit beta
type - Trichomonas vaginalis G3
Length = 224
Score = 37.1 bits (82), Expect = 0.47
Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 1/125 (0%)
Frame = -2
Query: 724 NSGTVIGLRGKDGVVFAVEKLITSKLYEPGANK-RIFHIDEHVGMAVAGLISDARQIVET 548
+ GT IG+ G D VV + ++ +K RIF ++ + ++ G D +
Sbjct: 19 HGGTAIGICGDDYVVIGADTRLSVDYSIDSRHKARIFKMNSNCMISATGFDGDIDAFITR 78
Query: 547 ARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYM 368
RS NY +Q+ + ++ + VS +++ + PY ++++G ++Y
Sbjct: 79 MRSILLNYENQHFHEMSVESVARCVSNTLYSKRFF----PYYINILVGGINSEGKGKLYG 134
Query: 367 LDPSG 353
DP G
Sbjct: 135 YDPVG 139
>UniRef50_A2E7Z2 Cluster: Proteasome subunit beta type; n=1;
Trichomonas vaginalis G3|Rep: Proteasome subunit beta
type - Trichomonas vaginalis G3
Length = 216
Score = 37.1 bits (82), Expect = 0.47
Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 3/173 (1%)
Frame = -2
Query: 748 EYAAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPG-ANKRIFHIDEHVGMAVAGLIS 572
EY T++ ++ DGVV A + +S + P A +I I + A G +
Sbjct: 3 EYQFPKESMGTTLLAIQCTDGVVMASDSRTSSGSFIPNRATNKITEIQPKIFAARCGNAA 62
Query: 571 DARQIVETARS--EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTW 398
D + + ++ A N + + + + + Y Y + V++G W
Sbjct: 63 DTQFLARAVKNYLNALNITRENTDDSTILVASNVIRSLIVRYRQYLSA-----GVIVGGW 117
Query: 397 TDYEGPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREA 239
D GPQ+Y ++ SG++ + G + I++ D+T++E + A
Sbjct: 118 -DSAGPQVYSIEVSGMAIKKKIASNGSGSTYIQAYIDQNYREDMTMEEATKFA 169
>UniRef50_A6R393 Cluster: Proteasome component C5; n=5;
Ascomycota|Rep: Proteasome component C5 - Ajellomyces
capsulatus NAm1
Length = 266
Score = 36.7 bits (81), Expect = 0.62
Identities = 26/134 (19%), Positives = 59/134 (44%), Gaps = 9/134 (6%)
Frame = -2
Query: 727 ENSGTVIGLRGKDGVVFAVE-KLITSKLYEPGANKRIFHIDE--------HVGMAVAGLI 575
+N G+ +G+ GKD + A + + ++ ++F I E H+ ++V G
Sbjct: 39 DNGGSTLGIAGKDYAILAGDTRSVSGYNINTRYAPKLFKIGEGDECGEGAHLVLSVVGFA 98
Query: 574 SDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWT 395
+D R + E + Y+ ++G P+ + +R++ +++ + PY ++
Sbjct: 99 ADGRALKERLDAIVKMYKYKHGKPMSVNACAQRLATILYSKRFF----PYYVHAILAGMD 154
Query: 394 DYEGPQMYMLDPSG 353
+ +Y DP G
Sbjct: 155 EDGKGALYSYDPVG 168
>UniRef50_Q74MP5 Cluster: NEQ203; n=1; Nanoarchaeum equitans|Rep:
NEQ203 - Nanoarchaeum equitans
Length = 196
Score = 36.7 bits (81), Expect = 0.62
Identities = 17/61 (27%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLIT-SKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVETARS 539
T+IG++ +DGVV A +K + + E ++I I +++ +A +G ++D + I + ++
Sbjct: 3 TIIGIKARDGVVLASDKQASMGNIVEDKRAQKIIPITDYILLAGSGTVADLQHIAKILKT 62
Query: 538 E 536
E
Sbjct: 63 E 63
>UniRef50_Q5HZD9 Cluster: Putative uncharacterized protein; n=1;
Rattus norvegicus|Rep: Putative uncharacterized protein
- Rattus norvegicus (Rat)
Length = 99
Score = 36.3 bits (80), Expect = 0.82
Identities = 19/62 (30%), Positives = 32/62 (51%)
Frame = -2
Query: 589 VAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVV 410
+ G+ +D+R V A EA+N++ + G P+ L +R+ YT + VR C +
Sbjct: 1 MVGITADSRFQVPRAHYEAANWKDKCGYEFPVGVLCKRIDDVSQVYTQDNEVRLLCCMIC 60
Query: 409 MG 404
MG
Sbjct: 61 MG 62
>UniRef50_Q0AUA9 Cluster: Peptidase M23B precursor; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Peptidase M23B precursor - Syntrophomonas wolfei subsp.
wolfei (strain Goettingen)
Length = 283
Score = 36.3 bits (80), Expect = 0.82
Identities = 16/54 (29%), Positives = 28/54 (51%)
Frame = -2
Query: 604 HVGMAVAGLISDARQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLY 443
H G+ +AG + D + A E + Y+ YG + LK+ N + ++Y H +Y
Sbjct: 185 HHGLDIAGKVGDPIRAASDASVEHAGYQPIYGQTIILKHENGKKTVYAHLEKIY 238
>UniRef50_Q23FB2 Cluster: Proteasome, putative; n=5;
Oligohymenophorea|Rep: Proteasome, putative -
Tetrahymena thermophila SB210
Length = 297
Score = 36.3 bits (80), Expect = 0.82
Identities = 37/167 (22%), Positives = 71/167 (42%), Gaps = 3/167 (1%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIVETARS 539
T + + + GV+ AV+ + ++ ++I I++ + +AG +D + +
Sbjct: 76 TTLAFKFQGGVIVAVDSRASQGSFDASETVRKIIEINDQLLGTMAGGAADCQFWEQYLAI 135
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
E Y+ Q V + + + +++Y + GC M T D+EG Q+Y LD
Sbjct: 136 ECRKYQLQNREKVSVAAASRILINILYSYRNHGL--SMGC---MLTGWDHEGAQLYYLDN 190
Query: 358 SG--VSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARIIY 224
G + + F C G A ++ +L+VKE + IY
Sbjct: 191 DGQRIKGNIFSC--GSGSTYAYGVLDNEYHYNLSVKEAAELGRKAIY 235
>UniRef50_Q7DLS1 Cluster: Proteasome subunit beta type-7-B
precursor; n=28; Eukaryota|Rep: Proteasome subunit beta
type-7-B precursor - Arabidopsis thaliana (Mouse-ear
cress)
Length = 274
Score = 35.9 bits (79), Expect = 1.1
Identities = 36/173 (20%), Positives = 70/173 (40%), Gaps = 1/173 (0%)
Frame = -2
Query: 742 AAKAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDA 566
A ++ T++GL KDGV+ + T N ++I ++ ++ AG +D
Sbjct: 32 APSFLKTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADT 91
Query: 565 RQIVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYE 386
+ + S+ +R Q G + + + H ++ V ++V+G D
Sbjct: 92 EAVTDMVSSQLRLHRYQTGR--DSRVVTALTLLKKHLFSYQGHV---SAALVLG-GVDIT 145
Query: 385 GPQMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
GP ++ + P G + + +G AA + E LT E ++ A I
Sbjct: 146 GPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAEAI 198
>UniRef50_P49721 Cluster: Proteasome subunit beta type-2; n=40;
Fungi/Metazoa group|Rep: Proteasome subunit beta type-2
- Homo sapiens (Human)
Length = 201
Score = 35.9 bits (79), Expect = 1.1
Identities = 27/119 (22%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Frame = -2
Query: 712 VIGLRGKDGVVFAVEKLITSKLYE-PGANKRIFHIDEHVGMAVAGLISDARQIVETARSE 536
+IG++G D V+ A +++ S + + + ++F + E + + G D Q E +
Sbjct: 4 LIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKN 63
Query: 535 ASNYRSQYGSPV-PLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLD 362
Y+ + G + P N + A L S PY ++++ + ++EGP +Y +D
Sbjct: 64 VQLYKMRNGYELSPTAAAN--FTRRNLADCLRSRT-PYHVNLLLAGYDEHEGPALYYMD 119
>UniRef50_A0RU86 Cluster: 20S proteasome, alpha and beta subunit;
n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha
and beta subunit - Cenarchaeum symbiosum
Length = 193
Score = 35.1 bits (77), Expect = 1.9
Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 1/162 (0%)
Frame = -2
Query: 715 TVIGLRGKDGVVFAVEKLITSKLYEPGANKR-IFHIDEHVGMAVAGLISDARQIVETARS 539
T +G+ GV+ A EK I + N R F I +VG A AGL++D + + +
Sbjct: 5 TAVGITYAGGVILASEKRIAYGNFLVSKNTRKTFQITPYVGAACAGLVADMQILSLQISA 64
Query: 538 EASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYMLDP 359
A + +P + + +S M+ + P V++G P +Y LD
Sbjct: 65 LAKIRKMDLKRDIPPNSVAKMMSNMMYERRFF----PLLTQVIVGGVVG--EPAIYTLDS 118
Query: 358 SGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAAR 233
G AVG + A ++ ++ K+ V A R
Sbjct: 119 LGSVLPDEYAAVGTGAEMALGVLDPQFKSGMSEKDAVDLAVR 160
>UniRef50_P25043 Cluster: Proteasome component PUP1 precursor; n=19;
Eukaryota|Rep: Proteasome component PUP1 precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 261
Score = 34.7 bits (76), Expect = 2.5
Identities = 37/171 (21%), Positives = 68/171 (39%), Gaps = 1/171 (0%)
Frame = -2
Query: 736 KAVENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQ 560
KA T++G++ +GVV A + T N ++ I + A AG +D
Sbjct: 24 KATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 83
Query: 559 IVETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGP 380
+ + S S Y S P + ++ + H + + Y +V G D G
Sbjct: 84 VTQLIGSNI-ELHSLYTSREP-RVVSALQMLKQHLFKYQGHIGAY--LIVAG--VDPTGS 137
Query: 379 QMYMLDPSGVSFSYFGCAVGKAKQAAKTEIEKLKLGDLTVKELVREAARII 227
++ + G + + ++G AA +E DLT +E ++ A+ I
Sbjct: 138 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAI 188
>UniRef50_Q7QWS6 Cluster: Proteasome subunit beta type; n=1; Giardia
lamblia ATCC 50803|Rep: Proteasome subunit beta type -
Giardia lamblia ATCC 50803
Length = 254
Score = 34.3 bits (75), Expect = 3.3
Identities = 26/128 (20%), Positives = 61/128 (47%), Gaps = 2/128 (1%)
Frame = -2
Query: 730 VENSGTVIGLRGKDGVVFAVEKLITSKLYEPGAN-KRIFHIDEHVGMAVAGLISDARQIV 554
++N GT+I + G D + A + ++ N +++F + + + A +G+ +D ++++
Sbjct: 52 IDNGGTIIAIAGPDFAMIAGDTRLSEGYNILSRNVRKVFPVTDKIVYAASGMHADVQRLL 111
Query: 553 ETARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRP-YGCSVVMGTWTDYEGPQ 377
+ + E++ Y + + ++ +S M+ Y P Y S+V G ++ G
Sbjct: 112 KHMKIESTEYYLKTQKEIAIEQFIRLLSAMMY----YRRSFPWYTSSIVAGIDSEGRG-A 166
Query: 376 MYMLDPSG 353
+Y D G
Sbjct: 167 VYSYDVIG 174
>UniRef50_Q9N9W8 Cluster: Proteasome subunit beta type-3; n=2;
Giardia intestinalis|Rep: Proteasome subunit beta type-3
- Giardia lamblia (Giardia intestinalis)
Length = 207
Score = 34.3 bits (75), Expect = 3.3
Identities = 20/93 (21%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = -2
Query: 724 NSGTVIGLRGKDGVVFAVEKLI--TSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVE 551
N +IG++G D V A +K + + + G +RIF + + + +AGL +D
Sbjct: 8 NGSALIGIKGXDCVALAADKRLGCSYQTLTIGNEERIFRLSQSCLLGLAGLQTDVLTTYR 67
Query: 550 TARSEASNYRSQYGSPVPLKYLNERVSMYMHAY 452
R +++ Y Q + + + +S +++ +
Sbjct: 68 QIRMKSNLYHLQEDREIRPRATAKMISSFLYKH 100
>UniRef50_P23724 Cluster: Proteasome component C5; n=23;
Fungi/Metazoa group|Rep: Proteasome component C5 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 241
Score = 33.9 bits (74), Expect = 4.4
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 1/139 (0%)
Frame = -2
Query: 727 ENSGTVIGLRGKDGVVFAVE-KLITSKLYEPGANKRIFHIDEHVGMAVAGLISDARQIVE 551
+N GT++G+ G+D V A + + IT ++F +++ M+ G +D +V+
Sbjct: 26 DNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVK 85
Query: 550 TARSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMY 371
++ Y + +N H Y +++ G D +G +Y
Sbjct: 86 RFKNSVKWYHFDHND--KKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKG-AVY 142
Query: 370 MLDPSGVSFSYFGCAVGKA 314
DP G S+ C G A
Sbjct: 143 SFDPVG-SYEREQCRAGGA 160
>UniRef50_UPI0000499AD3 Cluster: kinesin family protein; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: kinesin family
protein - Entamoeba histolytica HM-1:IMSS
Length = 863
Score = 26.2 bits (55), Expect(2) = 4.7
Identities = 9/39 (23%), Positives = 24/39 (61%)
Frame = -2
Query: 289 EKLKLGDLTVKELVREAARIIYLVHDELKDKQFELELSW 173
EK+K D +K++ I + +++++++ E+++SW
Sbjct: 441 EKIKQNDDIIKQIQENENEIEKKITEQIEEEKKEIQMSW 479
Score = 26.2 bits (55), Expect(2) = 4.7
Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Frame = -2
Query: 190 ELELSWVSKDTKGRHELVPRE-LATEAENQ 104
E W+ KDT GR E+ +E L E EN+
Sbjct: 502 EFNQQWIYKDTLGRMEIFCKEGLKQEKENK 531
>UniRef50_UPI0000E81D63 Cluster: PREDICTED: similar to RP5-1022P6.2,
partial; n=1; Gallus gallus|Rep: PREDICTED: similar to
RP5-1022P6.2, partial - Gallus gallus
Length = 141
Score = 33.1 bits (72), Expect = 7.6
Identities = 13/51 (25%), Positives = 29/51 (56%)
Frame = -2
Query: 301 KTEIEKLKLGDLTVKELVREAARIIYLVHDELKDKQFELELSWVSKDTKGR 149
K + E L+L ++ VKEL + +++ ++ +D F +E+ W+ + G+
Sbjct: 49 KLDTEPLELFEIAVKELTFDQLQLLKVLESVSEDVGFNIEIKWICQQKDGQ 99
>UniRef50_Q62B05 Cluster: Type III secretion system protein BsaZ;
n=12; Burkholderia|Rep: Type III secretion system
protein BsaZ - Burkholderia mallei (Pseudomonas mallei)
Length = 411
Score = 33.1 bits (72), Expect = 7.6
Identities = 18/62 (29%), Positives = 35/62 (56%)
Frame = -2
Query: 253 LVREAARIIYLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIED 74
L+ +AA +L H ELK + E++ + K+++G HE+ + E +++ A++E
Sbjct: 193 LILDAAVEYFLYHRELKMDKHEVKQEY--KESEGNHEIKSKRREIHQELLSEEIKANVEQ 250
Query: 73 SD 68
SD
Sbjct: 251 SD 252
>UniRef50_Q3VNT6 Cluster: Putative uncharacterized protein; n=1;
Pelodictyon phaeoclathratiforme BU-1|Rep: Putative
uncharacterized protein - Pelodictyon
phaeoclathratiforme BU-1
Length = 160
Score = 33.1 bits (72), Expect = 7.6
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = -2
Query: 253 LVREAARIIYLVHDELKDKQFELELSWVSKDTKGRHELVPRELATEAENQAKQALADIED 74
L+ +A+ IIY D +QF W+++ RH ++PR E +N+A + A ++D
Sbjct: 2 LIVDASSIIY-AWDNYPIRQFPGLWCWMAEQFTDRHLVMPRVAYDEVDNKAPECAAWLKD 60
Query: 73 SD 68
++
Sbjct: 61 AN 62
>UniRef50_Q5C084 Cluster: SJCHGC07669 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07669 protein - Schistosoma
japonicum (Blood fluke)
Length = 160
Score = 33.1 bits (72), Expect = 7.6
Identities = 19/68 (27%), Positives = 34/68 (50%)
Frame = -2
Query: 544 RSEASNYRSQYGSPVPLKYLNERVSMYMHAYTLYSAVRPYGCSVVMGTWTDYEGPQMYML 365
+S +SN Q G +K + + MH T++ VR Y CSV ++T + +++
Sbjct: 43 KSVSSNRTPQCGHC--MKKFSTLSYLRMHIATVHEGVRAYACSVCEKSYTQKHSLKKHLM 100
Query: 364 DPSGVSFS 341
+ +SFS
Sbjct: 101 NSHSISFS 108
>UniRef50_Q5ADT0 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 1197
Score = 33.1 bits (72), Expect = 7.6
Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 12/113 (10%)
Frame = -2
Query: 352 VSFSYFGC--AVGKAKQAAKTEIEKLKLGDLTV---------KELVREAARIIYLVHDEL 206
V FSY A K K+AA+ E +K K TV +E +A ++ + +
Sbjct: 64 VKFSYHPTLEAEAKKKKAAEAEAKKAKETKATVTSTEAKDAKEETETKAEKVEEKLETDA 123
Query: 205 KDKQFELELSWVSK-DTKGRHELVPRELATEAENQAKQALADIEDSDEGEM*T 50
K+ E E +K DT+ + L+ E E N+A++ A++ED E ++ T
Sbjct: 124 KEPLIEDETKEEAKVDTEAKEPLIEDEDKQEPANEAEEKEAELEDKAEEKLVT 176
>UniRef50_A0B983 Cluster: SMC domain protein; n=1; Methanosaeta
thermophila PT|Rep: SMC domain protein - Methanosaeta
thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 1061
Score = 33.1 bits (72), Expect = 7.6
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Frame = -2
Query: 280 KLGDLTVKELVREAARIIYLVH---DELKDKQFELELSWVSKDTKGRHELVPRELAT-EA 113
++G K+ +RE R I L EL D + +E +++ R EL+ RE+A +A
Sbjct: 170 EIGLEITKDDLREIERRINLASGALSELGDVERRIE-EIRAQEASARAELIKREIALKDA 228
Query: 112 ENQAKQALADIEDSDE 65
EN+ K+A D+E DE
Sbjct: 229 ENERKRAREDLERLDE 244
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 705,009,288
Number of Sequences: 1657284
Number of extensions: 13660603
Number of successful extensions: 43424
Number of sequences better than 10.0: 159
Number of HSP's better than 10.0 without gapping: 41581
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43288
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62558016040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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