BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= an--0387 (767 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 217 3e-56 AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 217 3e-56 AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 217 3e-56 AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 217 3e-56 BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 186 8e-47 AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 186 8e-47 AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 186 8e-47 AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 186 8e-47 AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 186 8e-47 AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 186 8e-47 D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 184 2e-46 BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 184 2e-46 BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 184 2e-46 AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 184 2e-46 AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 184 2e-46 BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 183 5e-46 AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 183 5e-46 U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 180 7e-45 AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 178 2e-44 AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 178 2e-44 AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 178 2e-44 D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 177 4e-44 AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 177 4e-44 AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 177 4e-44 S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 176 8e-44 S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 176 8e-44 L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 175 2e-43 D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 175 2e-43 AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 175 2e-43 AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 175 2e-43 AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 175 2e-43 AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 174 3e-43 X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 174 3e-43 J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 174 3e-43 DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 174 3e-43 BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 174 3e-43 AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 174 3e-43 AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 174 3e-43 AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 174 3e-43 AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 174 3e-43 AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 174 3e-43 AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 174 3e-43 AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 174 3e-43 AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 174 3e-43 AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 174 3e-43 AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 173 4e-43 AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 173 6e-43 AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 172 1e-42 BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 171 3e-42 AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 171 3e-42 AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 171 3e-42 AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 170 5e-42 D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 169 7e-42 BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 167 3e-41 AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 167 3e-41 AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 167 3e-41 AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 167 3e-41 AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 167 3e-41 AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 167 3e-41 AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 167 3e-41 BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 161 2e-39 BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 161 2e-39 BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 161 2e-39 AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 161 2e-39 BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 152 2e-36 BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 151 2e-36 AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 151 2e-36 AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 149 8e-36 AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 149 8e-36 AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 149 8e-36 AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 149 8e-36 AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 148 2e-35 M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 140 5e-33 DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 140 5e-33 DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 140 5e-33 BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 140 5e-33 BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 140 5e-33 AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 140 5e-33 AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 140 5e-33 AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 140 5e-33 AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 140 5e-33 AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 140 5e-33 M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 140 7e-33 J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 140 7e-33 X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 139 9e-33 M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 138 2e-32 D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 138 2e-32 AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 138 2e-32 D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 136 8e-32 BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 136 8e-32 AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 136 8e-32 AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 136 8e-32 J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 135 2e-31 BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 135 2e-31 AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 135 2e-31 AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 134 2e-31 AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 134 3e-31 BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 134 4e-31 AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 134 4e-31 AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 134 4e-31 AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 134 4e-31 AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 134 4e-31 AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 134 4e-31 X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 133 6e-31 AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 130 7e-30 AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 130 7e-30 AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 110 6e-24 AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 107 4e-23 M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 107 6e-23 BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 107 6e-23 BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 107 6e-23 AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 107 6e-23 AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 107 6e-23 AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 106 8e-23 D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 105 1e-22 AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 105 1e-22 BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 105 2e-22 AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 105 2e-22 AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 104 4e-22 AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 104 4e-22 AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 104 4e-22 BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 101 4e-21 U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 100 5e-21 U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 100 5e-21 D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 100 5e-21 AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 100 5e-21 Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 97 8e-20 X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 97 8e-20 M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 97 8e-20 M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 97 8e-20 M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 97 8e-20 M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 97 8e-20 J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 97 8e-20 DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 97 8e-20 BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 97 8e-20 BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 97 8e-20 AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 97 8e-20 BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 95 2e-19 AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 95 2e-19 AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 95 2e-19 AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 95 2e-19 BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 94 6e-19 AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 94 6e-19 X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 92 2e-18 M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 92 2e-18 BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 92 2e-18 BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 92 2e-18 AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 92 2e-18 X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 91 3e-18 X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 91 3e-18 M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 91 3e-18 L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 91 3e-18 BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 91 3e-18 BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 91 3e-18 BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 91 3e-18 BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 91 3e-18 AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 91 3e-18 U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 91 4e-18 BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 91 4e-18 AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 91 4e-18 AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 91 4e-18 AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 91 5e-18 M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 90 7e-18 X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 90 9e-18 BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 90 9e-18 S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 89 2e-17 AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 89 2e-17 AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 89 2e-17 AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 89 2e-17 AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 89 2e-17 BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 89 2e-17 AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 89 2e-17 AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 89 2e-17 AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 89 2e-17 AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 89 2e-17 AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 89 2e-17 AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 88 3e-17 DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 88 4e-17 BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 87 5e-17 X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 87 7e-17 M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 87 7e-17 M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 87 7e-17 M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 87 7e-17 D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 87 7e-17 DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17 BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 87 7e-17 BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 87 7e-17 AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 87 7e-17 AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 87 7e-17 AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 87 9e-17 Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 86 1e-16 X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 86 1e-16 M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 86 1e-16 M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 86 1e-16 M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 86 1e-16 BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 86 1e-16 AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 86 1e-16 AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 86 1e-16 X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 86 2e-16 X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 86 2e-16 BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 86 2e-16 S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 85 2e-16 M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 85 2e-16 M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 85 2e-16 M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 85 2e-16 M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 85 2e-16 D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 85 2e-16 DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 85 2e-16 BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16 BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 85 2e-16 BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 85 2e-16 AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16 AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16 AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16 AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 85 2e-16 AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 85 2e-16 U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 85 3e-16 DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 85 3e-16 CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 85 3e-16 BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 85 3e-16 BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 85 3e-16 BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 85 3e-16 BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 85 3e-16 BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 85 3e-16 BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 85 3e-16 AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 85 3e-16 AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 85 3e-16 M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 85 3e-16 M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 85 3e-16 BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 85 3e-16 BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 85 3e-16 AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 85 3e-16 AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 85 3e-16 M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 84 5e-16 DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 84 5e-16 BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 84 5e-16 BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 84 5e-16 U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 84 6e-16 M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 83 1e-15 BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 83 1e-15 X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 82 2e-15 M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 82 2e-15 L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 82 2e-15 J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 82 2e-15 J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 82 2e-15 DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 82 2e-15 DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 82 2e-15 BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 82 2e-15 AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 82 2e-15 AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 82 2e-15 AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 82 2e-15 M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 82 2e-15 L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 82 2e-15 BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 82 2e-15 BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 82 2e-15 BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 82 2e-15 U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 81 3e-15 AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 81 3e-15 M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 81 4e-15 M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 81 4e-15 M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 81 4e-15 M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 81 4e-15 DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 81 4e-15 BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 81 4e-15 BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 81 4e-15 BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 81 4e-15 BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 81 4e-15 AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 81 4e-15 AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 81 4e-15 AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 81 4e-15 AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 81 4e-15 AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 81 4e-15 AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 81 4e-15 AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 81 4e-15 AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 81 4e-15 AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 81 4e-15 AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 81 4e-15 L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 79 1e-14 BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 79 2e-14 AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 79 2e-14 AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 79 2e-14 AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 79 2e-14 X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 78 4e-14 M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 78 4e-14 M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 78 4e-14 M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 78 4e-14 BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 78 4e-14 L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 77 9e-14 X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 76 1e-13 EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 76 2e-13 AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 76 2e-13 D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 75 2e-13 AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 2e-13 M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 75 3e-13 M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 75 3e-13 M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 75 3e-13 M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 75 3e-13 J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 75 3e-13 BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 75 3e-13 BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 75 3e-13 BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 75 3e-13 BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 75 3e-13 BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 75 3e-13 AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13 AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13 AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13 AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13 AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13 AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13 AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 75 3e-13 AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 75 3e-13 AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 75 3e-13 AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 75 3e-13 AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 75 3e-13 AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 75 3e-13 AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 75 3e-13 AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 75 3e-13 AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 75 3e-13 K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 75 4e-13 AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 74 5e-13 AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 74 5e-13 X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 73 9e-13 M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 73 9e-13 AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 73 9e-13 X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 73 1e-12 M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 73 1e-12 K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 73 1e-12 EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12 BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12 AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 73 1e-12 AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 73 1e-12 AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 73 1e-12 AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12 AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 73 1e-12 M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 71 3e-12 AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 71 6e-12 BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 70 8e-12 BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 70 8e-12 BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 70 8e-12 M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 70 1e-11 AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 70 1e-11 BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 69 1e-11 AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 69 1e-11 AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 69 1e-11 AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 69 1e-11 U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 69 2e-11 BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 69 2e-11 BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 69 2e-11 AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 69 2e-11 U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 68 3e-11 AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 68 3e-11 AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 68 3e-11 AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 67 6e-11 BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 66 1e-10 AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 64 5e-10 AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 64 5e-10 AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 64 7e-10 AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 60 6e-09 DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 60 9e-09 AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 59 1e-08 BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 57 6e-08 AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 57 8e-08 EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 56 2e-07 AF297052-1|AAG31785.1| 500|Homo sapiens prostacyclin synthase p... 52 2e-06 D84124-1|BAA28219.1| 509|Homo sapiens prostacyclin synthase pro... 52 3e-06 D83402-1|BAA11910.1| 500|Homo sapiens prostacyclin synthase pro... 52 3e-06 D38145-1|BAA07343.1| 500|Homo sapiens prostacyclin synthase pro... 52 3e-06 BC101811-1|AAI01812.1| 500|Homo sapiens prostaglandin I2 (prost... 52 3e-06 BC101809-1|AAI01810.1| 500|Homo sapiens prostaglandin I2 (prost... 52 3e-06 AL118525-1|CAC14162.1| 500|Homo sapiens prostaglandin I2 (prost... 52 3e-06 AF297051-1|AAG31784.1| 500|Homo sapiens prostacyclin synthase p... 52 3e-06 AF297050-1|AAG31783.1| 500|Homo sapiens prostacyclin synthase p... 52 3e-06 AF297049-1|AAG31782.1| 500|Homo sapiens prostacyclin synthase p... 52 3e-06 AF297048-1|AAG31781.1| 500|Homo sapiens prostacyclin synthase p... 52 3e-06 L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 51 5e-06 DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 50 7e-06 BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 49 2e-05 BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 48 3e-05 BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 48 3e-05 AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 48 3e-05 AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 47 6e-05 BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 46 1e-04 BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 46 1e-04 AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 46 1e-04 AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 46 1e-04 AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 46 1e-04 AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 46 1e-04 AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 46 2e-04 BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 45 3e-04 BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 45 3e-04 X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 44 6e-04 M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 44 6e-04 BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 44 6e-04 BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 44 6e-04 AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 44 6e-04 AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 44 8e-04 AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 44 8e-04 AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 43 0.001 AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 43 0.001 BC029155-1|AAH29155.1| 489|Homo sapiens CYP7B1 protein protein. 41 0.004 X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 40 0.010 X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 40 0.010 X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 40 0.010 X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 40 0.010 X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 40 0.010 AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 36 0.21 EF122243-1|ABO41978.1| 47|Homo sapiens cytochrome P450 2F1 var... 35 0.28 M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 33 0.85 S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 32 2.0 S77873-1|AAD14267.1| 68|Homo sapiens CYP2E1 protein. 31 3.4 X80821-1|CAA56787.1| 150|Homo sapiens ribosomal protein L18a ho... 31 4.5 D50111-1|BAA08796.1| 46|Homo sapiens CYP2EI protein. 30 7.9 >BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4, subfamily V, polypeptide 2 protein. Length = 525 Score = 217 bits (531), Expect = 3e-56 Identities = 103/216 (47%), Positives = 148/216 (68%), Gaps = 1/216 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + KR AFLDLLL + G +S E+I+E+VDT MFEGHDTTAA ++ L ++G + ++Q Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 KV ELD +FG SDRP T +D +++YLE + ETLRL+P VP+ AR V+++ + G Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 ++ GT VI Y LHR P +PNP +F P+ F PE + RH YA+VPFSAGPR+C+G+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470 Query: 563 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADII 670 K+A+++ K ILS ILR+F + S+ K + L+ +I Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLI 506 >AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 protein. Length = 525 Score = 217 bits (531), Expect = 3e-56 Identities = 103/216 (47%), Positives = 148/216 (68%), Gaps = 1/216 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + KR AFLDLLL + G +S E+I+E+VDT MFEGHDTTAA ++ L ++G + ++Q Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 KV ELD +FG SDRP T +D +++YLE + ETLRL+P VP+ AR V+++ + G Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 ++ GT VI Y LHR P +PNP +F P+ F PE + RH YA+VPFSAGPR+C+G+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470 Query: 563 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADII 670 K+A+++ K ILS ILR+F + S+ K + L+ +I Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLI 506 >AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens cDNA FLJ44509 fis, clone UTERU3001585, weakly similar to Cytochrome P450 4c3 (EC 1.14.-.-). ). Length = 503 Score = 217 bits (531), Expect = 3e-56 Identities = 103/216 (47%), Positives = 148/216 (68%), Gaps = 1/216 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + KR AFLDLLL + G +S E+I+E+VDT MFEGHDTTAA ++ L ++G + ++Q Sbjct: 271 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 330 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 KV ELD +FG SDRP T +D +++YLE + ETLRL+P VP+ AR V+++ + G Sbjct: 331 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 388 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 ++ GT VI Y LHR P +PNP +F P+ F PE + RH YA+VPFSAGPR+C+G+ Sbjct: 389 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 448 Query: 563 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADII 670 K+A+++ K ILS ILR+F + S+ K + L+ +I Sbjct: 449 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLI 484 >AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar to CYTOCHROME P450 4C1 (EC 1.14.14.1). ). Length = 525 Score = 217 bits (531), Expect = 3e-56 Identities = 103/216 (47%), Positives = 148/216 (68%), Gaps = 1/216 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + KR AFLDLLL + G +S E+I+E+VDT MFEGHDTTAA ++ L ++G + ++Q Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 KV ELD +FG SDRP T +D +++YLE + ETLRL+P VP+ AR V+++ + G Sbjct: 353 KKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--G 410 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 ++ GT VI Y LHR P +PNP +F P+ F PE + RH YA+VPFSAGPR+C+G+ Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQ 470 Query: 563 KYAMLKLKVILSTILRNFRVISDLKESDFKLQADII 670 K+A+++ K ILS ILR+F + S+ K + L+ +I Sbjct: 471 KFAVMEEKTILSCILRHFWIESNQKREELGLEGQLI 506 >BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 12 protein. Length = 524 Score = 186 bits (453), Expect = 8e-47 Identities = 92/228 (40%), Positives = 142/228 (62%), Gaps = 2/228 (0%) Frame = +2 Query: 5 DVDDDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 181 D D + K L F+D LLL + G A+SDE+I+ + DT MF GHDTTA+G S+ L + Sbjct: 285 DFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 344 Query: 182 GIHQDIQDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 H + Q++ +E+ ++ D D + + + D ++ +L C+ E+LRL+PP P I+R Q Sbjct: 345 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQ 404 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 538 +I LP +G+ IP G T +I +H P V+P+P +DP F PE S R AF+PFSA Sbjct: 405 DIVLP-DGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSA 463 Query: 539 GPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 GPR+C+G+ +AM ++KV+L+ +L +FR + D E KL+ + +E G Sbjct: 464 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 511 >AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. Length = 524 Score = 186 bits (453), Expect = 8e-47 Identities = 92/228 (40%), Positives = 142/228 (62%), Gaps = 2/228 (0%) Frame = +2 Query: 5 DVDDDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 181 D D + K L F+D LLL + G A+SDE+I+ + DT MF GHDTTA+G S+ L + Sbjct: 285 DFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 344 Query: 182 GIHQDIQDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 H + Q++ +E+ ++ D D + + + D ++ +L C+ E+LRL+PP P I+R Q Sbjct: 345 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQ 404 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 538 +I LP +G+ IP G T +I +H P V+P+P +DP F PE S R AF+PFSA Sbjct: 405 DIVLP-DGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSA 463 Query: 539 GPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 GPR+C+G+ +AM ++KV+L+ +L +FR + D E KL+ + +E G Sbjct: 464 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 511 >AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform 4F12 protein. Length = 524 Score = 186 bits (453), Expect = 8e-47 Identities = 92/228 (40%), Positives = 142/228 (62%), Gaps = 2/228 (0%) Frame = +2 Query: 5 DVDDDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 181 D D + K L F+D LLL + G A+SDE+I+ + DT MF GHDTTA+G S+ L + Sbjct: 285 DFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 344 Query: 182 GIHQDIQDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 H + Q++ +E+ ++ D D + + + D ++ +L C+ E+LRL+PP P I+R Q Sbjct: 345 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQ 404 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 538 +I LP +G+ IP G T +I +H P V+P+P +DP F PE S R AF+PFSA Sbjct: 405 DIVLP-DGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSA 463 Query: 539 GPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 GPR+C+G+ +AM ++KV+L+ +L +FR + D E KL+ + +E G Sbjct: 464 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 511 >AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. Length = 458 Score = 186 bits (453), Expect = 8e-47 Identities = 92/228 (40%), Positives = 142/228 (62%), Gaps = 2/228 (0%) Frame = +2 Query: 5 DVDDDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 181 D D + K L F+D LLL + G A+SDE+I+ + DT MF GHDTTA+G S+ L + Sbjct: 219 DFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 278 Query: 182 GIHQDIQDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 H + Q++ +E+ ++ D D + + + D ++ +L C+ E+LRL+PP P I+R Q Sbjct: 279 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQ 338 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 538 +I LP +G+ IP G T +I +H P V+P+P +DP F PE S R AF+PFSA Sbjct: 339 DIVLP-DGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSA 397 Query: 539 GPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 GPR+C+G+ +AM ++KV+L+ +L +FR + D E KL+ + +E G Sbjct: 398 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 445 >AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. Length = 524 Score = 186 bits (453), Expect = 8e-47 Identities = 92/228 (40%), Positives = 142/228 (62%), Gaps = 2/228 (0%) Frame = +2 Query: 5 DVDDDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 181 D D + K L F+D LLL + G A+SDE+I+ + DT MF GHDTTA+G S+ L + Sbjct: 285 DFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 344 Query: 182 GIHQDIQDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 H + Q++ +E+ ++ D D + + + D ++ +L C+ E+LRL+PP P I+R Q Sbjct: 345 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQ 404 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 538 +I LP +G+ IP G T +I +H P V+P+P +DP F PE S R AF+PFSA Sbjct: 405 DIVLP-DGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSA 463 Query: 539 GPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 GPR+C+G+ +AM ++KV+L+ +L +FR + D E KL+ + +E G Sbjct: 464 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 511 >AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. Length = 524 Score = 186 bits (453), Expect = 8e-47 Identities = 92/228 (40%), Positives = 142/228 (62%), Gaps = 2/228 (0%) Frame = +2 Query: 5 DVDDDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMM 181 D D + K L F+D LLL + G A+SDE+I+ + DT MF GHDTTA+G S+ L + Sbjct: 285 DFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNL 344 Query: 182 GIHQDIQDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 H + Q++ +E+ ++ D D + + + D ++ +L C+ E+LRL+PP P I+R Q Sbjct: 345 ARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQ 404 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSA 538 +I LP +G+ IP G T +I +H P V+P+P +DP F PE S R AF+PFSA Sbjct: 405 DIVLP-DGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSA 463 Query: 539 GPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 GPR+C+G+ +AM ++KV+L+ +L +FR + D E KL+ + +E G Sbjct: 464 GPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGG 511 >D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 184 bits (449), Expect = 2e-46 Identities = 89/221 (40%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 protein. Length = 520 Score = 184 bits (449), Expect = 2e-46 Identities = 89/221 (40%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 protein. Length = 520 Score = 184 bits (449), Expect = 2e-46 Identities = 89/221 (40%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily IVF, polypeptide 2 protein. Length = 520 Score = 184 bits (449), Expect = 2e-46 Identities = 89/221 (40%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. Length = 520 Score = 184 bits (449), Expect = 2e-46 Identities = 89/221 (40%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 protein. Length = 520 Score = 183 bits (446), Expect = 5e-46 Identities = 88/221 (39%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P ++P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 183 bits (446), Expect = 5e-46 Identities = 88/221 (39%), Positives = 139/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LRL+PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P ++P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. Length = 520 Score = 180 bits (437), Expect = 7e-45 Identities = 87/221 (39%), Positives = 138/221 (62%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+ S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D + +L C+ E+LR++PPVP+I+R V Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F PE R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L FRV+ D E K + + +E G Sbjct: 471 QTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. Length = 520 Score = 178 bits (434), Expect = 2e-44 Identities = 82/207 (39%), Positives = 132/207 (63%), Gaps = 2/207 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL ++G +SDE+I+ + DT MF GHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D ++ +L CL E+LRL+PP+P AR Q++ LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDS 411 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 + IP G I + +H P V+P+P +DP F PE + R AF+PFSAGPR+C+G Sbjct: 412 -RVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKE 640 +K+AM ++KV+L+ L FR++ D +E Sbjct: 471 QKFAMAEMKVVLALTLLRFRILPDHRE 497 >AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 3 protein. Length = 520 Score = 178 bits (433), Expect = 2e-44 Identities = 86/221 (38%), Positives = 137/221 (61%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D ++ +L C+ E+LRL+PPVP ++R Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F P+ R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L L FRV+ D E K + + +E G Sbjct: 471 QAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. Length = 520 Score = 178 bits (433), Expect = 2e-44 Identities = 86/221 (38%), Positives = 137/221 (61%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D ++ +L C+ E+LRL+PPVP ++R Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F P+ R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L L FRV+ D E K + + +E G Sbjct: 471 QAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGG 511 >D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV protein. Length = 520 Score = 177 bits (431), Expect = 4e-44 Identities = 86/221 (38%), Positives = 137/221 (61%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D ++ +L C+ E+LRL+PPVP ++R Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F P+ R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L L FRV+ D E K + + +E G Sbjct: 471 QAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGG 511 >AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 177 bits (431), Expect = 4e-44 Identities = 86/221 (38%), Positives = 137/221 (61%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D ++ +L C+ E+LRL+PPVP ++R Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F P+ R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L L FRV+ D E K + + +E G Sbjct: 471 QAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGG 511 >AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 177 bits (431), Expect = 4e-44 Identities = 86/221 (38%), Positives = 137/221 (61%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + + D ++ +L C+ E+LRL+PPVP ++R Q+I LP + Sbjct: 352 ERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I+ + H P V+P+P +DP F P+ R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L L FRV+ D E K + + +E G Sbjct: 471 QAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGG 511 >S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase protein. Length = 591 Score = 176 bits (428), Expect = 8e-44 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase protein. Length = 519 Score = 176 bits (428), Expect = 8e-44 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. Length = 519 Score = 175 bits (425), Expect = 2e-43 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxylase protein. Length = 519 Score = 175 bits (425), Expect = 2e-43 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 11 protein. Length = 519 Score = 175 bits (425), Expect = 2e-43 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 protein. Length = 519 Score = 175 bits (425), Expect = 2e-43 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPD 483 >AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 11 protein. Length = 519 Score = 175 bits (425), Expect = 2e-43 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K protein. Length = 519 Score = 174 bits (424), Expect = 3e-43 Identities = 83/207 (40%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPD 483 >X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for cytochrome P-450HP. ). Length = 511 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cytochrome P450 (IV subfamily) BI protein, complete cds. ). Length = 511 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 511 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 512 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 338 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488 >AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450 4B1 variant protein. Length = 497 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 263 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 322 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 323 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 380 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 381 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 441 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 473 >AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450 4B1 protein. Length = 512 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 338 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488 >AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. Length = 511 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 512 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 338 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488 >AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 511 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 497 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 263 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 322 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 323 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 380 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 381 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 441 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 473 >AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 512 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 278 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 337 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 338 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 395 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 396 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 456 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488 >AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 511 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 497 Score = 174 bits (423), Expect = 3e-43 Identities = 83/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL M ++ + Sbjct: 263 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPE 322 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 323 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 380 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 381 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 441 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 473 >AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. Length = 511 Score = 173 bits (422), Expect = 4e-43 Identities = 83/213 (38%), Positives = 133/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT G S+FL M ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily IVA, polypeptide 11 protein. Length = 519 Score = 173 bits (421), Expect = 6e-43 Identities = 82/207 (39%), Positives = 131/207 (63%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRL+PPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPD 483 >AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. Length = 511 Score = 172 bits (419), Expect = 1e-42 Identities = 82/213 (38%), Positives = 134/213 (62%), Gaps = 1/213 (0%) Frame = +2 Query: 20 VGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQD 196 + ++ L FLD+LL + + + +SD +++ +VDT MFEGHDTT +G S+FL + ++ + Sbjct: 277 IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPE 336 Query: 197 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 376 Q + EE+ +I GD D + D +M YL C+ E+ RLYPPVP + RQ+++ +T Sbjct: 337 HQHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFV- 394 Query: 377 NGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCV 556 +G+ +PAG+ + + Y LHR V+P+P FD F E ++ RH +AF+PFSAGPR+C+ Sbjct: 395 DGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454 Query: 557 GRKYAMLKLKVILSTILRNFRVISDLKESDFKL 655 G+++AM ++KV+ + L F D K+ Sbjct: 455 GQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487 >BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. Length = 524 Score = 171 bits (415), Expect = 3e-42 Identities = 84/221 (38%), Positives = 135/221 (61%), Gaps = 2/221 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSDR-PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + D ++ +L C+ E+LRL+PPVP+I+R Q+ LP + Sbjct: 352 EQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I +H P V+P+P +DP F E R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVISDLKESDFKLQADIISETG 682 + +AM ++KV+L+ L +FR++ E K + + +E G Sbjct: 471 QAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGG 511 >AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22 protein. Length = 519 Score = 171 bits (415), Expect = 3e-42 Identities = 82/207 (39%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PN FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPD 483 >AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydroxylase CYP4A11 protein. Length = 519 Score = 171 bits (415), Expect = 3e-42 Identities = 82/207 (39%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PN FDP F P + +H +AF+PFS G R+ Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAP--GSAQHSHAFLPFSGGSRN 456 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM +LKV + L F ++ D Sbjct: 457 CIGKQFAMNQLKVARALTLLRFELLPD 483 >AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. Length = 524 Score = 170 bits (413), Expect = 5e-42 Identities = 80/202 (39%), Positives = 128/202 (63%), Gaps = 2/202 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 + K L F+D LLL + G +SDE+I+ + DT MFEGHDTTA+G S+ L + H + Q Sbjct: 292 KSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351 Query: 203 DKVIEELDQIFGDSDR-PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 ++ +E+ ++ D + + + D ++ +L C+ E+LRL+PPVP+I+R Q+ LP + Sbjct: 352 EQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP-D 410 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +I +H P V+P+P +DP F E R AF+PFSAGPR+C+G Sbjct: 411 GRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIG 470 Query: 560 RKYAMLKLKVILSTILRNFRVI 625 + +AM ++KV+L+ L +FR++ Sbjct: 471 QAFAMAEMKVVLALTLLHFRIL 492 >D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase protein. Length = 521 Score = 169 bits (412), Expect = 7e-42 Identities = 80/193 (41%), Positives = 125/193 (64%), Gaps = 1/193 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 282 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 341 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 342 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 400 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R+ Sbjct: 401 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSRN 457 Query: 551 CVGRKYAMLKLKV 589 C+G+++AM +LKV Sbjct: 458 CIGKQFAMNELKV 470 >BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4, subfamily X, polypeptide 1 protein. Length = 509 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 276 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 335 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 336 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 395 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 453 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 454 CIGQEFAMIELKVTIALILLHFRVTPD 480 >AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. Length = 509 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 276 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 335 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 336 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 395 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 453 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 454 CIGQEFAMIELKVTIALILLHFRVTPD 480 >AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. Length = 509 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 276 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 335 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 336 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 395 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 453 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 454 CIGQEFAMIELKVTIALILLHFRVTPD 480 >AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4, subfamily X, polypeptide 1 protein. Length = 509 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 276 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 335 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 336 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 395 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 453 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 454 CIGQEFAMIELKVTIALILLHFRVTPD 480 >AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar to CYTOCHROME P450 4A4 (EC 1.14.14.1). ). Length = 508 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 275 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 334 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 335 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 393 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 394 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 452 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 453 CIGQEFAMIELKVTIALILLHFRVTPD 479 >AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to CYTOCHROME P450 4A4 (EC 1.14.14.1). ). Length = 509 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 276 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 335 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 336 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 395 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 453 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 454 CIGQEFAMIELKVTIALILLHFRVTPD 480 >AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to CYTOCHROME P450 4A4 (EC 1.14.14.1). ). Length = 444 Score = 167 bits (407), Expect = 3e-41 Identities = 83/207 (40%), Positives = 130/207 (62%), Gaps = 1/207 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 D+ ++K FLD++L + +SG + SD ++ +V T + GHDT AA S+ L + ++ Sbjct: 211 DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 270 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 + Q++ EE+ I GD +T+ EM Y C+ ET RL P VP I+R +++ +T Sbjct: 271 PEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 329 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 P +G +PAG T+V++ + LH P V+ NP FDP F E S RH YA++PFSAG R+ Sbjct: 330 P-DGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRN 388 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISD 631 C+G+++AM++LKV ++ IL +FRV D Sbjct: 389 CIGQEFAMIELKVTIALILLHFRVTPD 415 >BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 protein. Length = 531 Score = 161 bits (392), Expect = 2e-39 Identities = 77/204 (37%), Positives = 126/204 (61%), Gaps = 2/204 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q K L F+D LLL + G +SDE+I+ + DT MFEGHDTT++G S+ L + + + Q Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358 Query: 203 DKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 +K EE+ ++ G + + D ++ + C+ E+LR YPPV +++RQ ++I LP + Sbjct: 359 EKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-D 417 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +++ Y H P V+P+ ++P F P+ R A+VPFSAGPR+C+G Sbjct: 418 GRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477 Query: 560 RKYAMLKLKVILSTILRNFRVISD 631 + +AM +L+V+++ L FR+ D Sbjct: 478 QSFAMAELRVVVALTLLRFRLSVD 501 >BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 protein. Length = 531 Score = 161 bits (392), Expect = 2e-39 Identities = 77/204 (37%), Positives = 126/204 (61%), Gaps = 2/204 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q K L F+D LLL + G +SDE+I+ + DT MFEGHDTT++G S+ L + + + Q Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358 Query: 203 DKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 +K EE+ ++ G + + D ++ + C+ E+LR YPPV +++RQ ++I LP + Sbjct: 359 EKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-D 417 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +++ Y H P V+P+ ++P F P+ R A+VPFSAGPR+C+G Sbjct: 418 GRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477 Query: 560 RKYAMLKLKVILSTILRNFRVISD 631 + +AM +L+V+++ L FR+ D Sbjct: 478 QSFAMAELRVVVALTLLRFRLSVD 501 >BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 protein. Length = 531 Score = 161 bits (392), Expect = 2e-39 Identities = 77/204 (37%), Positives = 126/204 (61%), Gaps = 2/204 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q K L F+D LLL + G +SDE+I+ + DT MFEGHDTT++G S+ L + + + Q Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358 Query: 203 DKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 +K EE+ ++ G + + D ++ + C+ E+LR YPPV +++RQ ++I LP + Sbjct: 359 EKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-D 417 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +++ Y H P V+P+ ++P F P+ R A+VPFSAGPR+C+G Sbjct: 418 GRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477 Query: 560 RKYAMLKLKVILSTILRNFRVISD 631 + +AM +L+V+++ L FR+ D Sbjct: 478 QSFAMAELRVVVALTLLRFRLSVD 501 >AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens cDNA FLJ39501 fis, clone PROST2016980, moderately similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ). Length = 531 Score = 161 bits (392), Expect = 2e-39 Identities = 77/204 (37%), Positives = 126/204 (61%), Gaps = 2/204 (0%) Frame = +2 Query: 26 QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q K L F+D LLL + G +SDE+I+ + DT MFEGHDTT++G S+ L + + + Q Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358 Query: 203 DKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 379 +K EE+ ++ G + + D ++ + C+ E+LR YPPV +++RQ ++I LP + Sbjct: 359 EKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP-D 417 Query: 380 GKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVG 559 G+ IP G +++ Y H P V+P+ ++P F P+ R A+VPFSAGPR+C+G Sbjct: 418 GRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477 Query: 560 RKYAMLKLKVILSTILRNFRVISD 631 + +AM +L+V+++ L FR+ D Sbjct: 478 QSFAMAELRVVVALTLLRFRLSVD 501 >BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. Length = 455 Score = 152 bits (368), Expect = 2e-36 Identities = 73/179 (40%), Positives = 112/179 (62%), Gaps = 1/179 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAP--GSAQHSHAFLPFSGGSR 455 >BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. Length = 455 Score = 151 bits (367), Expect = 2e-36 Identities = 73/179 (40%), Positives = 112/179 (62%), Gaps = 1/179 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSR 455 >AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 11 protein. Length = 455 Score = 151 bits (367), Expect = 2e-36 Identities = 73/179 (40%), Positives = 112/179 (62%), Gaps = 1/179 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 P +G+ +P G ++++ Y LH P V+PNP FDP F P + +H +AF+PFS G R Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAP--GSAQHSHAFLPFSGGSR 455 >AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. Length = 505 Score = 149 bits (362), Expect = 8e-36 Identities = 75/206 (36%), Positives = 125/206 (60%), Gaps = 1/206 (0%) Frame = +2 Query: 17 DVGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 193 D QK+R FLD+LL + S++ S+ +++ +V T MF GHDTT++ S+ L + + Sbjct: 275 DTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYP 334 Query: 194 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 373 + Q + +E+ ++ GD +T++ +M Y C+ E LRLY PV I+R +++ IT P Sbjct: 335 EHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP 393 Query: 374 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 553 +G+ +PAG T+ I + LH P + +P F+P F E S H YAF+PFSAG R+C Sbjct: 394 -DGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNC 452 Query: 554 VGRKYAMLKLKVILSTILRNFRVISD 631 +G+ +A+++ KV ++ L F++ D Sbjct: 453 IGQHFAIIECKVAVALTLLRFKLAPD 478 >AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. Length = 505 Score = 149 bits (362), Expect = 8e-36 Identities = 75/206 (36%), Positives = 125/206 (60%), Gaps = 1/206 (0%) Frame = +2 Query: 17 DVGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 193 D QK+R FLD+LL + S++ S+ +++ +V T MF GHDTT++ S+ L + + Sbjct: 275 DTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYP 334 Query: 194 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 373 + Q + +E+ ++ GD +T++ +M Y C+ E LRLY PV I+R +++ IT P Sbjct: 335 EHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP 393 Query: 374 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 553 +G+ +PAG T+ I + LH P + +P F+P F E S H YAF+PFSAG R+C Sbjct: 394 -DGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNC 452 Query: 554 VGRKYAMLKLKVILSTILRNFRVISD 631 +G+ +A+++ KV ++ L F++ D Sbjct: 453 IGQHFAIIECKVAVALTLLRFKLAPD 478 >AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4, subfamily Z, polypeptide 1 protein. Length = 505 Score = 149 bits (362), Expect = 8e-36 Identities = 75/206 (36%), Positives = 125/206 (60%), Gaps = 1/206 (0%) Frame = +2 Query: 17 DVGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 193 D QK+R FLD+LL + S++ S+ +++ +V T MF GHDTT++ S+ L + + Sbjct: 275 DTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYP 334 Query: 194 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 373 + Q + +E+ ++ GD +T++ +M Y C+ E LRLY PV I+R +++ IT P Sbjct: 335 EHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP 393 Query: 374 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 553 +G+ +PAG T+ I + LH P + +P F+P F E S H YAF+PFSAG R+C Sbjct: 394 -DGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNC 452 Query: 554 VGRKYAMLKLKVILSTILRNFRVISD 631 +G+ +A+++ KV ++ L F++ D Sbjct: 453 IGQHFAIIECKVAVALTLLRFKLAPD 478 >AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4, subfamily Z, polypeptide 1 protein. Length = 505 Score = 149 bits (362), Expect = 8e-36 Identities = 75/206 (36%), Positives = 125/206 (60%), Gaps = 1/206 (0%) Frame = +2 Query: 17 DVGQKKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQ 193 D QK+R FLD+LL + S++ S+ +++ +V T MF GHDTT++ S+ L + + Sbjct: 275 DTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYP 334 Query: 194 DIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 373 + Q + +E+ ++ GD +T++ +M Y C+ E LRLY PV I+R +++ IT P Sbjct: 335 EHQQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP 393 Query: 374 SNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSC 553 +G+ +PAG T+ I + LH P + +P F+P F E S H YAF+PFSAG R+C Sbjct: 394 -DGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNC 452 Query: 554 VGRKYAMLKLKVILSTILRNFRVISD 631 +G+ +A+++ KV ++ L F++ D Sbjct: 453 IGQHFAIIECKVAVALTLLRFKLAPD 478 >AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22 protein. Length = 455 Score = 148 bits (358), Expect = 2e-35 Identities = 72/179 (40%), Positives = 111/179 (62%), Gaps = 1/179 (0%) Frame = +2 Query: 14 DDVGQKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 + + +K+ L FLD LLL ++G +SD++++ +VDT MFEGHDTTA+G S+ L + H Sbjct: 281 EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATH 340 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 Q++ EE+ + GD +T+ +M Y C+ E LRLYPPVP I R+++ +T Sbjct: 341 PKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 399 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 P +G+ +P G ++++ Y LH P V+PN FDP F P + +H +AF+PFS G R Sbjct: 400 P-DGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAP--GSAQHSHAFLPFSGGSR 455 >M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA encoding nifedipine oxidase, complete cds. ). Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3 subfamily A polypeptide 4 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily IIIA, polypeptide 4 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. Length = 353 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 115 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 174 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 175 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 233 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 234 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 291 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 292 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 329 >AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. Length = 430 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 192 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 251 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 252 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 310 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 311 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 368 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 369 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 406 >AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypeptide 4 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 protein. Length = 503 Score = 140 bits (339), Expect = 5e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome P-450 nifedipine oxidase mRNA, complet cds. ). Length = 503 Score = 140 bits (338), Expect = 7e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine oxidase protein. Length = 502 Score = 140 bits (338), Expect = 7e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 264 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 323 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 324 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 382 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 383 --NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRN 440 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 441 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 478 >X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for cytochrome P-450 (cyp3 locus). ). Length = 503 Score = 139 bits (337), Expect = 9e-33 Identities = 73/219 (33%), Positives = 125/219 (57%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glucocorticoid-inducible cytochrome P-450 (HLp) mRNA, complete cds. ). Length = 504 Score = 138 bits (335), Expect = 2e-32 Identities = 73/220 (33%), Positives = 125/220 (56%), Gaps = 6/220 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES------SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 187 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324 Query: 188 HQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 367 H D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ Sbjct: 325 HPDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383 Query: 368 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 + NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR Sbjct: 384 I--NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441 Query: 548 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 +C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 NCIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 480 >D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. Length = 504 Score = 138 bits (335), Expect = 2e-32 Identities = 73/220 (33%), Positives = 125/220 (56%), Gaps = 6/220 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES------SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGI 187 QK R+ FL L+++S ++S A+SD E+ Q +F G++TT++ SF + + Sbjct: 265 QKHRVDFLQLMIDSHKNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELAT 324 Query: 188 HQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEIT 367 H D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ Sbjct: 325 HPDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVE 383 Query: 368 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 + NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR Sbjct: 384 I--NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPR 441 Query: 548 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 +C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 NCIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 480 >AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 protein. Length = 503 Score = 138 bits (334), Expect = 2e-32 Identities = 73/219 (33%), Positives = 124/219 (56%), Gaps = 5/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S ++S A+SD E+ Q +F G +TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + P T+ L+M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LHR P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQADI 667 C+G ++A++ +K+ L +L+NF KE+ L+ + Sbjct: 442 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLSL 479 >D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa protein. Length = 503 Score = 136 bits (329), Expect = 8e-32 Identities = 71/216 (32%), Positives = 123/216 (56%), Gaps = 5/216 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S S++ A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q KV +E+D + + P T+ L+++YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LH P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQ 658 C+G ++A++ +K+ L +L+NF KE+ L+ Sbjct: 442 CIGMRFALVNMKLALVRVLQNFS-FKPCKETQIPLK 476 >BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 7 protein. Length = 503 Score = 136 bits (329), Expect = 8e-32 Identities = 71/216 (32%), Positives = 123/216 (56%), Gaps = 5/216 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S S++ A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q KV +E+D + + P T+ L+++YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LH P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQ 658 C+G ++A++ +K+ L +L+NF KE+ L+ Sbjct: 442 CIGMRFALVNMKLALVRVLQNFS-FKPCKETQIPLK 476 >AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant 3A7 protein. Length = 535 Score = 136 bits (329), Expect = 8e-32 Identities = 71/216 (32%), Positives = 123/216 (56%), Gaps = 5/216 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S S++ A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q KV +E+D + + P T+ L+++YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LH P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQ 658 C+G ++A++ +K+ L +L+NF KE+ L+ Sbjct: 442 CIGMRFALVNMKLALVRVLQNFS-FKPCKETQIPLK 476 >AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypeptide 7 protein. Length = 503 Score = 136 bits (329), Expect = 8e-32 Identities = 71/216 (32%), Positives = 123/216 (56%), Gaps = 5/216 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ FL L+++S S++ A+SD E+ Q +F G++TT++ SF + + H Sbjct: 265 QKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q KV +E+D + + P T+ L+++YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G ++I +Y LH P + P KF P+ F + N Y + PF +GPR+ Sbjct: 384 --NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQ 658 C+G ++A++ +K+ L +L+NF KE+ L+ Sbjct: 442 CIGMRFALVNMKLALVRVLQNFS-FKPCKETQIPLK 476 >J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 protein. Length = 502 Score = 135 bits (326), Expect = 2e-31 Identities = 73/218 (33%), Positives = 125/218 (57%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK RL FL L+++S ++S A+SD E+ Q +F G++TT++ SF L + H Sbjct: 265 QKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ +E+D + + P T+ ++M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G+ +VI TY LH P + P +F P+ F ++ + Y + PF GPR+ Sbjct: 384 --NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYI-YTPFGTGPRN 440 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A++ +K+ L +L+NF KE+ L+ D Sbjct: 441 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLD 477 >BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 5 protein. Length = 502 Score = 135 bits (326), Expect = 2e-31 Identities = 73/218 (33%), Positives = 125/218 (57%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK RL FL L+++S ++S A+SD E+ Q +F G++TT++ SF L + H Sbjct: 265 QKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ +E+D + + P T+ ++M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G+ +VI TY LH P + P +F P+ F ++ + Y + PF GPR+ Sbjct: 384 --NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYI-YTPFGTGPRN 440 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A++ +K+ L +L+NF KE+ L+ D Sbjct: 441 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLD 477 >AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. Length = 502 Score = 135 bits (326), Expect = 2e-31 Identities = 73/218 (33%), Positives = 125/218 (57%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK RL FL L+++S ++S A+SD E+ Q +F G++TT++ SF L + H Sbjct: 265 QKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ +E+D + + P T+ ++M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G+ +VI TY LH P + P +F P+ F ++ + Y + PF GPR+ Sbjct: 384 --NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYI-YTPFGTGPRN 440 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A++ +K+ L +L+NF KE+ L+ D Sbjct: 441 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLD 477 >AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3 protein. Length = 503 Score = 134 bits (325), Expect = 2e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLANK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 478 >AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 5 variant protein. Length = 502 Score = 134 bits (324), Expect = 3e-31 Identities = 73/218 (33%), Positives = 125/218 (57%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK RL FL L+++S ++S A+SD E+ Q +F G++TT++ SF L + H Sbjct: 265 QKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ +E+D + + P T+ ++M+YL+ + ETLRL+P + R +++ + Sbjct: 325 PDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G+ +VI TY LH P + P +F P+ F ++ + Y + PF GPR+ Sbjct: 384 --NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYI-YTPFGTGPRN 440 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A++ +K+ L +L+NF KE+ L+ D Sbjct: 441 CIGMRFALMNMKLALIRVLQNFS-FKPCKETQIPLKLD 477 >BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. Length = 393 Score = 134 bits (323), Expect = 4e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 155 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 214 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 215 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 273 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 274 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 331 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 332 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 368 >AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1 protein. Length = 503 Score = 134 bits (323), Expect = 4e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 478 >AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 503 Score = 134 bits (323), Expect = 4e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 478 >AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43 protein. Length = 503 Score = 134 bits (323), Expect = 4e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 478 >AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 503 Score = 134 bits (323), Expect = 4e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 478 >AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. Length = 503 Score = 134 bits (323), Expect = 4e-31 Identities = 71/218 (32%), Positives = 120/218 (55%), Gaps = 5/218 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRS 550 NG IP G +++ Y LH P + P KF P+ F + + Y ++PF AGPR+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRN 441 Query: 551 CVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 CIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 478 >X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. Length = 141 Score = 133 bits (322), Expect = 6e-31 Identities = 62/145 (42%), Positives = 91/145 (62%) Frame = +2 Query: 119 TIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERC 298 T MFEGHDTTA+G S+ L + H Q++ EE+ + GD +T+ +M Y C Sbjct: 1 TFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMC 59 Query: 299 LMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 + E LRLYPPVP I+R+++ +T P +G+ +P G T++++ Y LH P V+PNP FDP Sbjct: 60 IKEALRLYPPVPGISRELSTPVTFP-DGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPS 118 Query: 479 NFLPERSANRHYYAFVPFSAGPRSC 553 F P + +H +AF+PFS G R+C Sbjct: 119 RFAP--GSAQHSHAFLPFSGGSRNC 141 >AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 504 Score = 130 bits (313), Expect = 7e-30 Identities = 71/219 (32%), Positives = 121/219 (55%), Gaps = 6/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDN-FLPERSANRHYYAFVPFSAGPR 547 NG IP G +++ Y LH P + P KF P++ F + + Y ++PF AGPR Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPR 441 Query: 548 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 +C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 NCIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 479 >AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. Length = 504 Score = 130 bits (313), Expect = 7e-30 Identities = 71/219 (32%), Positives = 121/219 (55%), Gaps = 6/219 (2%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDN-FLPERSANRHYYAFVPFSAGPR 547 NG IP G +++ Y LH P + P KF P++ F + + Y ++PF AGPR Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPR 441 Query: 548 SCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQAD 664 +C+G ++A+ +K+ + L+NF KE+ L+ D Sbjct: 442 NCIGMRFALTNIKLAVIRALQNFS-FKPCKETQIPLKLD 479 >AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22 protein. Length = 421 Score = 110 bits (264), Expect = 6e-24 Identities = 49/119 (41%), Positives = 76/119 (63%) Frame = +2 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 454 +M Y C+ E LRLYPPVP I R+++ +T P +G+ +P G ++++ Y LH P V+P Sbjct: 270 QMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DGRSLPKGIMVLLSIYGLHHNPKVWP 328 Query: 455 NPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 N FDP F P + +H +AF+PFS G R+C+G+++AM +LKV + L F ++ D Sbjct: 329 NLEVFDPSRFAP--GSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPD 385 >AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (257), Expect = 4e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. Length = 466 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 262 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 320 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 321 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 378 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 379 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 437 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 438 CPETQVPLQLESKSALG 454 >AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) iso protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 107 bits (256), Expect = 6e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 106 bits (255), Expect = 8e-23 Identities = 61/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase protein. Length = 533 Score = 105 bits (253), Expect = 1e-22 Identities = 61/197 (30%), Positives = 100/197 (50%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 329 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 387 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ Q+ + G++IPAG L +A LH P+ + Sbjct: 388 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 445 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G +L++K+ L +L FR Sbjct: 446 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFR-FQA 504 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 505 CPETQVPLQLESKSALG 521 >AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase protein. Length = 534 Score = 105 bits (253), Expect = 1e-22 Identities = 60/197 (30%), Positives = 101/197 (51%), Gaps = 1/197 (0%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 +EI Q + G++ SF ++ + D Q+K++ E+D +F + F Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVD-VFKEKHMAPEFCSLE 388 Query: 275 E-MKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 451 E + YL+ + ETLR+YPP R+ ++ + G++IPAG L +A LH P+ + Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVL--GQRIPAGAVLEMAVGALHHDPEHW 446 Query: 452 PNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISD 631 P+P F+P+ F E + ++PF AGPRSC+G + +L++K+ L +L FR Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFR-FQA 505 Query: 632 LKESDFKLQADIISETG 682 E+ LQ + S G Sbjct: 506 CPETQVPLQLESKSALG 522 >BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family 46, subfamily A, polypeptide 1 protein. Length = 500 Score = 105 bits (252), Expect = 2e-22 Identities = 57/183 (31%), Positives = 105/183 (57%), Gaps = 2/183 (1%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 A DE + + T GH+T+A +F + + +I ++ E+D++ G S R + F Sbjct: 286 AQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDF 344 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 +D ++YL + L E+LRLYPP R + +E + +G ++P T L+ +TY + R Sbjct: 345 EDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI--DGVRVPGNTPLLFSTYVMGRMD 402 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR--NF 616 + +P F+PD F P A + + + PFS G RSC+G+++A +++KV+++ +L+ F Sbjct: 403 TYFEDPLTFNPDRFGP--GAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 460 Query: 617 RVI 625 R++ Sbjct: 461 RLV 463 >AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase protein. Length = 500 Score = 105 bits (252), Expect = 2e-22 Identities = 57/183 (31%), Positives = 105/183 (57%), Gaps = 2/183 (1%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 A DE + + T GH+T+A +F + + +I ++ E+D++ G S R + F Sbjct: 286 AQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDF 344 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 +D ++YL + L E+LRLYPP R + +E + +G ++P T L+ +TY + R Sbjct: 345 EDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI--DGVRVPGNTPLLFSTYVMGRMD 402 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR--NF 616 + +P F+PD F P A + + + PFS G RSC+G+++A +++KV+++ +L+ F Sbjct: 403 TYFEDPLTFNPDRFGP--GAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 460 Query: 617 RVI 625 R++ Sbjct: 461 RLV 463 >AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family 26, subfamily A, polypeptide 1 protein. Length = 428 Score = 104 bits (249), Expect = 4e-22 Identities = 57/194 (29%), Positives = 104/194 (53%), Gaps = 5/194 (2%) Frame = +2 Query: 47 LDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 L LL+E S + G + + +K+ ++F GH+TTA+ ++ ++ +G++ + KV EEL Sbjct: 202 LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEL 261 Query: 224 DQ----IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 391 + D + + ++KY+ + ETLRL PPVP R + L NG +I Sbjct: 262 KSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQI 319 Query: 392 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 571 P G ++ + H +++ N +F+PD F+ + ++F+PF G RSCVG+++A Sbjct: 320 PKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 379 Query: 572 MLKLKVILSTILRN 613 + LK+ + R+ Sbjct: 380 KILLKIFTVELARH 393 >AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family 26, subfamily A, polypeptide 1 protein. Length = 497 Score = 104 bits (249), Expect = 4e-22 Identities = 57/194 (29%), Positives = 104/194 (53%), Gaps = 5/194 (2%) Frame = +2 Query: 47 LDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 L LL+E S + G + + +K+ ++F GH+TTA+ ++ ++ +G++ + KV EEL Sbjct: 271 LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEL 330 Query: 224 DQ----IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 391 + D + + ++KY+ + ETLRL PPVP R + L NG +I Sbjct: 331 KSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQI 388 Query: 392 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 571 P G ++ + H +++ N +F+PD F+ + ++F+PF G RSCVG+++A Sbjct: 389 PKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 448 Query: 572 MLKLKVILSTILRN 613 + LK+ + R+ Sbjct: 449 KILLKIFTVELARH 462 >AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase protein. Length = 497 Score = 104 bits (249), Expect = 4e-22 Identities = 57/194 (29%), Positives = 104/194 (53%), Gaps = 5/194 (2%) Frame = +2 Query: 47 LDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 L LL+E S + G + + +K+ ++F GH+TTA+ ++ ++ +G++ + KV EEL Sbjct: 271 LQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEL 330 Query: 224 DQ----IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKI 391 + D + + ++KY+ + ETLRL PPVP R + L NG +I Sbjct: 331 KSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL--NGYQI 388 Query: 392 PAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYA 571 P G ++ + H +++ N +F+PD F+ + ++F+PF G RSCVG+++A Sbjct: 389 PKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFA 448 Query: 572 MLKLKVILSTILRN 613 + LK+ + R+ Sbjct: 449 KILLKIFTVELARH 462 >BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family 51, subfamily A, polypeptide 1 protein. Length = 509 Score = 101 bits (241), Expect = 4e-21 Identities = 57/196 (29%), Positives = 103/196 (52%), Gaps = 1/196 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q+K L LL+++ + G ++D+E+ + ++ G T++ S++ + + +Q Sbjct: 281 QEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQ 340 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 K E + G++ P+T+ ++ L+RC+ ETLRL PPV I+ R T+ G Sbjct: 341 KKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTVA--G 398 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 IP G + ++ R D + F+PD +L + A+ +A+VPF AG C+G Sbjct: 399 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458 Query: 563 KYAMLKLKVILSTILR 610 +A +++K I ST+LR Sbjct: 459 NFAYVQIKTIWSTMLR 474 >U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demethylase protein. Length = 503 Score = 100 bits (240), Expect = 5e-21 Identities = 56/196 (28%), Positives = 103/196 (52%), Gaps = 1/196 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q+K L LL+++ + G ++D+E+ + ++ G T++ S++ + + +Q Sbjct: 275 QEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQ 334 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 K E + G++ P+T+ ++ L+RC+ ETLRL PP+ I+ R T+ G Sbjct: 335 KKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTVA--G 392 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 IP G + ++ R D + F+PD +L + A+ +A+VPF AG C+G Sbjct: 393 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 452 Query: 563 KYAMLKLKVILSTILR 610 +A +++K I ST+LR Sbjct: 453 NFAYVQIKTIWSTMLR 468 >U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase cytochrome P450 protein. Length = 509 Score = 100 bits (240), Expect = 5e-21 Identities = 56/196 (28%), Positives = 103/196 (52%), Gaps = 1/196 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q+K L LL+++ + G ++D+E+ + ++ G T++ S++ + + +Q Sbjct: 281 QEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQ 340 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 K E + G++ P+T+ ++ L+RC+ ETLRL PP+ I+ R T+ G Sbjct: 341 KKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA--G 398 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 IP G + ++ R D + F+PD +L + A+ +A+VPF AG C+G Sbjct: 399 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458 Query: 563 KYAMLKLKVILSTILR 610 +A +++K I ST+LR Sbjct: 459 NFAYVQIKTIWSTMLR 474 >D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase protein. Length = 509 Score = 100 bits (240), Expect = 5e-21 Identities = 56/196 (28%), Positives = 103/196 (52%), Gaps = 1/196 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q+K L LL+++ + G ++D+E+ + ++ G T++ S++ + + +Q Sbjct: 281 QEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQ 340 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 K E + G++ P+T+ ++ L+RC+ ETLRL PP+ I+ R T+ G Sbjct: 341 KKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA--G 398 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 IP G + ++ R D + F+PD +L + A+ +A+VPF AG C+G Sbjct: 399 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458 Query: 563 KYAMLKLKVILSTILR 610 +A +++K I ST+LR Sbjct: 459 NFAYVQIKTIWSTMLR 474 >AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. Length = 509 Score = 100 bits (240), Expect = 5e-21 Identities = 56/196 (28%), Positives = 103/196 (52%), Gaps = 1/196 (0%) Frame = +2 Query: 26 QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQ 202 Q+K L LL+++ + G ++D+E+ + ++ G T++ S++ + + +Q Sbjct: 281 QEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQ 340 Query: 203 DKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNG 382 K E + G++ P+T+ ++ L+RC+ ETLRL PP+ I+ R T+ G Sbjct: 341 KKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA--G 398 Query: 383 KKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGR 562 IP G + ++ R D + F+PD +L + A+ +A+VPF AG C+G Sbjct: 399 YTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458 Query: 563 KYAMLKLKVILSTILR 610 +A +++K I ST+LR Sbjct: 459 NFAYVQIKTIWSTMLR 474 >Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for aromatase P-450. ). Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for aromatase (estrogen synthetase). ). Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase cytochrome P-450 gene, exon 10. ). Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase protein. Length = 419 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 207 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 264 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 265 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 321 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 322 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 376 >M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase mRNA, complete cds. ). Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase (Aro1) mRNA, complete cds. ). Length = 419 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 207 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 264 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 265 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 321 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 322 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 376 >J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily 19 subfamily A polypeptide 1 protein. Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 protein. Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 protein. Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 protein. Length = 503 Score = 96.7 bits (230), Expect = 8e-20 Identities = 49/179 (27%), Positives = 97/179 (54%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 ++ E + + + ++ DT + F L ++ H ++++ +I+E+ + G+ D + Sbjct: 291 LTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERD--IKID 348 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D ++K +E + E++R P V ++ R+ ++ + +G + GT +++ ++HR + Sbjct: 349 DIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI--DGYPVKKGTNIILNIGRMHRL-E 405 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 +P PN+F +NF + N Y F PF GPR C G+ AM+ +K IL T+LR F V Sbjct: 406 FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460 >BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2, subfamily U, polypeptide 1 protein. Length = 544 Score = 95.5 bits (227), Expect = 2e-19 Identities = 51/183 (27%), Positives = 95/183 (51%) Frame = +2 Query: 68 SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD 247 + S + +E + + + G DTT + L M ++ D+Q+KV EE++++ G ++ Sbjct: 331 NNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIG-AN 389 Query: 248 RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYK 427 R + D +M Y E +ME RL VP+ + E T+ G IP GT ++ + Sbjct: 390 RAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTV-LQGYTIPKGTLILPNLWS 448 Query: 428 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 607 +HR P ++ P F P+ FL ++ F+PF G R C+G + A ++L ++ +++ Sbjct: 449 VHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLM 508 Query: 608 RNF 616 ++F Sbjct: 509 QSF 511 >AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. Length = 544 Score = 95.5 bits (227), Expect = 2e-19 Identities = 51/183 (27%), Positives = 95/183 (51%) Frame = +2 Query: 68 SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSD 247 + S + +E + + + G DTT + L M ++ D+Q+KV EE++++ G ++ Sbjct: 331 NNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIG-AN 389 Query: 248 RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYK 427 R + D +M Y E +ME RL VP+ + E T+ G IP GT ++ + Sbjct: 390 RAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTV-LQGYTIPKGTLILPNLWS 448 Query: 428 LHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTIL 607 +HR P ++ P F P+ FL ++ F+PF G R C+G + A ++L ++ +++ Sbjct: 449 VHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLM 508 Query: 608 RNF 616 ++F Sbjct: 509 QSF 511 >AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein protein. Length = 173 Score = 95.1 bits (226), Expect = 2e-19 Identities = 46/138 (33%), Positives = 79/138 (57%) Frame = +2 Query: 251 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 430 P T+ ++M+YL+ + ETLRL+P + R +++ + NG IP G+ +VI TY L Sbjct: 15 PPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYAL 72 Query: 431 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 610 H P + P +F P+ F ++ + Y + PF GPR+C+G ++A++ +K+ L +L+ Sbjct: 73 HHDPKYWTEPEEFRPERFSKKKDSIDPYI-YTPFGTGPRNCIGMRFALMNMKLALIRVLQ 131 Query: 611 NFRVISDLKESDFKLQAD 664 NF KE+ L+ D Sbjct: 132 NFS-FKPCKETQIPLKLD 148 >AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. Length = 160 Score = 95.1 bits (226), Expect = 2e-19 Identities = 46/138 (33%), Positives = 79/138 (57%) Frame = +2 Query: 251 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 430 P T+ ++M+YL+ + ETLRL+P + R +++ + NG IP G+ +VI TY L Sbjct: 2 PPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYAL 59 Query: 431 HRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR 610 H P + P +F P+ F ++ + Y + PF GPR+C+G ++A++ +K+ L +L+ Sbjct: 60 HHDPKYWTEPEEFRPERFSKKKDSIDPYI-YTPFGTGPRNCIGMRFALMNMKLALIRVLQ 118 Query: 611 NFRVISDLKESDFKLQAD 664 NF KE+ L+ D Sbjct: 119 NFS-FKPCKETQIPLKLD 135 >BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. Length = 280 Score = 93.9 bits (223), Expect = 6e-19 Identities = 51/160 (31%), Positives = 89/160 (55%), Gaps = 5/160 (3%) Frame = +2 Query: 14 DDVGQKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSM 178 +++G + R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + Sbjct: 121 EELGLQHRVDFFQQIIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYE 180 Query: 179 MGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQ 358 + H D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R + Sbjct: 181 LATHPDVQQKLQEEIDAVL-PNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKK 239 Query: 359 EITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 +I + NG IP G +++ Y LH P + P KF P+ Sbjct: 240 DIEI--NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPE 277 >AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 420 Score = 93.9 bits (223), Expect = 6e-19 Identities = 52/156 (33%), Positives = 86/156 (55%), Gaps = 5/156 (3%) Frame = +2 Query: 26 QKKRLAFLDLLLES-----SQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIH 190 QK R+ F +++S ++S A+SD E+ Q I+F +DTT+ F + + H Sbjct: 265 QKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATH 324 Query: 191 QDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 370 D+Q K+ EE+D + + PVT+ ++M+YL+ + ETLRL+P V + R ++I + Sbjct: 325 PDVQQKLQEEIDAVL-PNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 383 Query: 371 PSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 NG IP G +++ Y LH P + P KF P+ Sbjct: 384 --NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPE 417 >X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase protein. Length = 530 Score = 92.3 bits (219), Expect = 2e-18 Identities = 61/220 (27%), Positives = 108/220 (49%), Gaps = 4/220 (1%) Frame = +2 Query: 44 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 +L LL S Q +S E + ++ G DTT+ ++ L + +IQ+ + EE+ Sbjct: 309 YLHFLLASGQ----LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEV 364 Query: 224 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 403 + P +D M L+ L ETLRLYP VP +R + +EI + +G P T Sbjct: 365 VGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNT 421 Query: 404 TLVIATYKLHRRPDVYPNPNKFDPDNFL----PERSANRHYYAFVPFSAGPRSCVGRKYA 571 V Y + R P + P F P +L P +H + VPF G R+C+GR+ A Sbjct: 422 QFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIA 481 Query: 572 MLKLKVILSTILRNFRVISDLKESDFKLQADIISETGRRI 691 L+++++L+ +++ ++V+ + + K A I+ +++ Sbjct: 482 ELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKV 521 >M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase protein. Length = 531 Score = 92.3 bits (219), Expect = 2e-18 Identities = 61/220 (27%), Positives = 108/220 (49%), Gaps = 4/220 (1%) Frame = +2 Query: 44 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 +L LL S Q +S E + ++ G DTT+ ++ L + +IQ+ + EE+ Sbjct: 310 YLHFLLASGQ----LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEV 365 Query: 224 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 403 + P +D M L+ L ETLRLYP VP +R + +EI + +G P T Sbjct: 366 VGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNT 422 Query: 404 TLVIATYKLHRRPDVYPNPNKFDPDNFL----PERSANRHYYAFVPFSAGPRSCVGRKYA 571 V Y + R P + P F P +L P +H + VPF G R+C+GR+ A Sbjct: 423 QFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIA 482 Query: 572 MLKLKVILSTILRNFRVISDLKESDFKLQADIISETGRRI 691 L+++++L+ +++ ++V+ + + K A I+ +++ Sbjct: 483 ELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKV 522 >BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family 27, subfamily A, polypeptide 1 protein. Length = 531 Score = 92.3 bits (219), Expect = 2e-18 Identities = 61/220 (27%), Positives = 108/220 (49%), Gaps = 4/220 (1%) Frame = +2 Query: 44 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 +L LL S Q +S E + ++ G DTT+ ++ L + +IQ+ + EE+ Sbjct: 310 YLHFLLASGQ----LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEV 365 Query: 224 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 403 + P +D M L+ L ETLRLYP VP +R + +EI + +G P T Sbjct: 366 VGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNT 422 Query: 404 TLVIATYKLHRRPDVYPNPNKFDPDNFL----PERSANRHYYAFVPFSAGPRSCVGRKYA 571 V Y + R P + P F P +L P +H + VPF G R+C+GR+ A Sbjct: 423 QFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIA 482 Query: 572 MLKLKVILSTILRNFRVISDLKESDFKLQADIISETGRRI 691 L+++++L+ +++ ++V+ + + K A I+ +++ Sbjct: 483 ELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKV 522 >BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family 27, subfamily A, polypeptide 1 protein. Length = 531 Score = 92.3 bits (219), Expect = 2e-18 Identities = 61/220 (27%), Positives = 108/220 (49%), Gaps = 4/220 (1%) Frame = +2 Query: 44 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 +L LL S Q +S E + ++ G DTT+ ++ L + +IQ+ + EE+ Sbjct: 310 YLHFLLASGQ----LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEV 365 Query: 224 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 403 + P +D M L+ L ETLRLYP VP +R + +EI + +G P T Sbjct: 366 VGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNT 422 Query: 404 TLVIATYKLHRRPDVYPNPNKFDPDNFL----PERSANRHYYAFVPFSAGPRSCVGRKYA 571 V Y + R P + P F P +L P +H + VPF G R+C+GR+ A Sbjct: 423 QFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIA 482 Query: 572 MLKLKVILSTILRNFRVISDLKESDFKLQADIISETGRRI 691 L+++++L+ +++ ++V+ + + K A I+ +++ Sbjct: 483 ELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKV 522 >AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase protein. Length = 531 Score = 92.3 bits (219), Expect = 2e-18 Identities = 61/220 (27%), Positives = 108/220 (49%), Gaps = 4/220 (1%) Frame = +2 Query: 44 FLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEEL 223 +L LL S Q +S E + ++ G DTT+ ++ L + +IQ + EE+ Sbjct: 310 YLHFLLASGQ----LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEV 365 Query: 224 DQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGT 403 + P +D M L+ L ETLRLYP VP +R + +EI + +G P T Sbjct: 366 VGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNT 422 Query: 404 TLVIATYKLHRRPDVYPNPNKFDPDNFL----PERSANRHYYAFVPFSAGPRSCVGRKYA 571 V Y++ R P + P F P +L P +H + VPF G R+C+GR+ A Sbjct: 423 QFVFCHYEVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIA 482 Query: 572 MLKLKVILSTILRNFRVISDLKESDFKLQADIISETGRRI 691 L+++++L+ +++ ++V+ + + K A I+ +++ Sbjct: 483 ELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKV 522 >X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA for P-450 IIA4 protein. ). Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd base in codon) protein. Length = 448 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 256 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 314 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 315 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 372 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 373 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 424 >M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 24-hydroxylase protein. Length = 513 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/179 (28%), Positives = 94/179 (52%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 +S +E+ V + +TTA + L + + +Q K+++E+ + ++ RP + Sbjct: 310 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPRE-E 368 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D M YL+ CL E++RL P VP R +++ L +P GT L++ T L D Sbjct: 369 DLRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYA--LPKGTVLMLNTQVLGSSED 426 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 + + ++F P+ +L E+ + +A +PF G R C+GR+ A L+L + L I+R + + Sbjct: 427 NFEDSSQFRPERWLQEKE-KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDI 484 >BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 6 protein. Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 6 protein. Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 6 protein. Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 6 protein. Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 protein. Length = 494 Score = 91.5 bits (217), Expect = 3e-18 Identities = 51/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + E Sbjct: 302 GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 360 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 361 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 418 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 419 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxygenase CYP2J2 protein. Length = 502 Score = 91.1 bits (216), Expect = 4e-18 Identities = 51/166 (30%), Positives = 89/166 (53%), Gaps = 1/166 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +TT+ + L M ++ +IQ+KV E+D++ G +P T M Y + Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVI 366 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R+ +P+ + R+V + TL G +P GT ++ LHR P + P+ F+PD Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLA--GYHLPKGTMILTNLTALHRDPTEWATPDTFNPD 424 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 +FL E + AF+PFS G R+C+G + A +L + +++++ F Sbjct: 425 HFL-ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469 >BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2, subfamily J, polypeptide 2 protein. Length = 502 Score = 91.1 bits (216), Expect = 4e-18 Identities = 51/166 (30%), Positives = 89/166 (53%), Gaps = 1/166 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +TT+ + L M ++ +IQ+KV E+D++ G +P T M Y + Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVI 366 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R+ +P+ + R+V + TL G +P GT ++ LHR P + P+ F+PD Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLA--GYHLPKGTMILTNLTALHRDPTEWATPDTFNPD 424 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 +FL E + AF+PFS G R+C+G + A +L + +++++ F Sbjct: 425 HFL-ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469 >AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2, subfamily J, polypeptide 2 protein. Length = 502 Score = 91.1 bits (216), Expect = 4e-18 Identities = 51/166 (30%), Positives = 89/166 (53%), Gaps = 1/166 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +TT+ + L M ++ +IQ+KV E+D++ G +P T M Y + Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVI 366 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R+ +P+ + R+V + TL G +P GT ++ LHR P + P+ F+PD Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLA--GYHLPKGTMILTNLTALHRDPTEWATPDTFNPD 424 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 +FL E + AF+PFS G R+C+G + A +L + +++++ F Sbjct: 425 HFL-ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469 >AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. Length = 502 Score = 91.1 bits (216), Expect = 4e-18 Identities = 51/166 (30%), Positives = 89/166 (53%), Gaps = 1/166 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +TT+ + L M ++ +IQ+KV E+D++ G +P T M Y + Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVI 366 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R+ +P+ + R+V + TL G +P GT ++ LHR P + P+ F+PD Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLA--GYHLPKGTMILTNLTALHRDPTEWATPDTFNPD 424 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 +FL E + AF+PFS G R+C+G + A +L + +++++ F Sbjct: 425 HFL-ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469 >AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 protein. Length = 502 Score = 90.6 bits (215), Expect = 5e-18 Identities = 51/166 (30%), Positives = 89/166 (53%), Gaps = 1/166 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +TT+ + L M ++ +IQ+KV E+D++ G +P T M Y + Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQPSTAARE-SMPYTNAVI 366 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R+ +P+ + R+V + TL G +P GT ++ LHR P + P+ F+PD Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLA--GYHLPKGTMILTNLTALHRDPTEWATPDTFNPD 424 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 +FL E + AF+PFS G R+C+G + A +L + +++++ F Sbjct: 425 HFL-ENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469 >M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. Length = 494 Score = 90.2 bits (214), Expect = 7e-18 Identities = 50/181 (27%), Positives = 93/181 (51%), Gaps = 1/181 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + Sbjct: 298 LFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRTKMPYMEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +AR+V ++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESDFKLQ 658 +FL ++ + AFVPFS G R C G A ++L + +T+++NFR+ S D + Sbjct: 415 HFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVS 474 Query: 659 A 661 + Sbjct: 475 S 475 >X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for cytochrome P-450IIA. ). Length = 489 Score = 89.8 bits (213), Expect = 9e-18 Identities = 50/172 (29%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +2 Query: 134 GHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETL 313 G +T + + ++ H +++ +V EE+D++ G + +P F+D +M Y+E + E Sbjct: 297 GTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVIHEIQ 355 Query: 314 RLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLP 490 R +P+ +AR+V ++ +P GT + + R P + NP F+P +FL Sbjct: 356 RFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLN 413 Query: 491 ERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 E+ + AFVPFS G R+C G A ++L + +T+++NFR+ S D Sbjct: 414 EKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 465 >BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 7 protein. Length = 494 Score = 89.8 bits (213), Expect = 9e-18 Identities = 50/176 (28%), Positives = 91/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y+E + Sbjct: 298 LFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYMEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +AR+V ++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKF--RDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +T+++NFR+ S D Sbjct: 415 HFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKSSQSPKD 470 >S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hydroxylase cytochrome P450 subunit protein. Length = 257 Score = 89.0 bits (211), Expect = 2e-17 Identities = 50/179 (27%), Positives = 93/179 (51%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 +S +E+ V + +TTA + L + + +Q K+++E+ + ++ P + Sbjct: 54 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-E 112 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D M YL+ CL E++RL P VP R +++ L +P GT L++ T L D Sbjct: 113 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYA--LPKGTVLMLNTQVLGSSED 170 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 + + ++F P+ +L E+ + +A +PF G R C+GR+ A L+L + L I+R + + Sbjct: 171 NFEDSSQFRPERWLQEKE-KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDI 228 >AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase splice variant protein. Length = 372 Score = 89.0 bits (211), Expect = 2e-17 Identities = 50/179 (27%), Positives = 93/179 (51%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 +S +E+ V + +TTA + L + + +Q K+++E+ + ++ P + Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-E 227 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D M YL+ CL E++RL P VP R +++ L +P GT L++ T L D Sbjct: 228 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYA--LPKGTVLMLNTQVLGSSED 285 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 + + ++F P+ +L E+ + +A +PF G R C+GR+ A L+L + L I+R + + Sbjct: 286 NFEDSSQFRPERWLQEKE-KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDI 343 >AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family 24, subfamily A, polypeptide 1 protein. Length = 514 Score = 89.0 bits (211), Expect = 2e-17 Identities = 50/179 (27%), Positives = 93/179 (51%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 +S +E+ V + +TTA + L + + +Q K+++E+ + ++ P + Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-E 369 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D M YL+ CL E++RL P VP R +++ L +P GT L++ T L D Sbjct: 370 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYA--LPKGTVLMLNTQVLGSSED 427 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 + + ++F P+ +L E+ + +A +PF G R C+GR+ A L+L + L I+R + + Sbjct: 428 NFEDSSQFRPERWLQEKE-KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDI 485 >AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family 24, subfamily A, polypeptide 1 protein. Length = 372 Score = 89.0 bits (211), Expect = 2e-17 Identities = 50/179 (27%), Positives = 93/179 (51%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQ 265 +S +E+ V + +TTA + L + + +Q K+++E+ + ++ P + Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRA-E 227 Query: 266 DTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPD 445 D M YL+ CL E++RL P VP R +++ L +P GT L++ T L D Sbjct: 228 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYA--LPKGTVLMLNTQVLGSSED 285 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 + + ++F P+ +L E+ + +A +PF G R C+GR+ A L+L + L I+R + + Sbjct: 286 NFEDSSQFRPERWLQEKE-KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDI 343 >AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. Length = 372 Score = 89.0 bits (211), Expect = 2e-17 Identities = 50/181 (27%), Positives = 96/181 (53%), Gaps = 1/181 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 A++ +EI V ++ G DTT+ S+ + ++ H ++Q V E+ + G+ P T Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVP-TA 222 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 D ++ + L ETLRL+P +P R +++ + G IP GT L + Y + Sbjct: 223 ADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVI--GGYLIPKGTQLALCHYATSYQD 280 Query: 443 DVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 619 + +P +F P+ +L + +R + +PF G RSC+GR+ A L++ +++ +L++F Sbjct: 281 ENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFE 340 Query: 620 V 622 + Sbjct: 341 I 341 >BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family 27, subfamily C, polypeptide 1 protein. Length = 372 Score = 88.6 bits (210), Expect = 2e-17 Identities = 50/181 (27%), Positives = 96/181 (53%), Gaps = 1/181 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 A++ +EI V ++ G DTT+ S+ + ++ H ++Q V E+ + G+ P T Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVP-TA 222 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 D ++ + L ETLRL+P +P R +++ + G IP GT L + Y + Sbjct: 223 ADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVI--GGYLIPKGTQLALCHYATSYQD 280 Query: 443 DVYPNPNKFDPDNFLPERSANR-HYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFR 619 + +P +F P+ +L + +R + +PF G RSC+GR+ A L++ +++ +L++F Sbjct: 281 ENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFE 340 Query: 620 V 622 + Sbjct: 341 I 341 >AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 variant 5 protein. Length = 494 Score = 88.6 bits (210), Expect = 2e-17 Identities = 52/176 (29%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 variant 3 protein. Length = 494 Score = 88.6 bits (210), Expect = 2e-17 Identities = 52/176 (29%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 variant 2 protein. Length = 494 Score = 88.6 bits (210), Expect = 2e-17 Identities = 52/176 (29%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 variant 1 protein. Length = 494 Score = 88.6 bits (210), Expect = 2e-17 Identities = 52/176 (29%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 protein. Length = 494 Score = 88.6 bits (210), Expect = 2e-17 Identities = 52/176 (29%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 variant 6 protein. Length = 494 Score = 88.2 bits (209), Expect = 3e-17 Identities = 52/176 (29%), Positives = 90/176 (51%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + + R P + NP F+P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL ++ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 protein. Length = 496 Score = 87.8 bits (208), Expect = 4e-17 Identities = 55/193 (28%), Positives = 98/193 (50%), Gaps = 1/193 (0%) Frame = +2 Query: 41 AFLDLLLESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE 220 AFL + + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E Sbjct: 274 AFLAEMEAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE 333 Query: 221 LDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPA 397 +D + G RP D M Y + E R VP+ + +++I + G +IP Sbjct: 334 IDDVIGQVRRP-EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPK 390 Query: 398 GTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAML 577 GTTL+ + + V+ P +F P++FL + AF+PFSAG R+C+G A + Sbjct: 391 GTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARM 450 Query: 578 KLKVILSTILRNF 616 +L + +++L++F Sbjct: 451 ELFLFFTSLLQHF 463 >BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. Length = 357 Score = 87.4 bits (207), Expect = 5e-17 Identities = 39/91 (42%), Positives = 57/91 (62%) Frame = +2 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYP 454 +M Y C+ E LRLYPPVP I R+++ +T P +G+ +P G ++++ Y LH P V+P Sbjct: 270 QMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DGRSLPKGIMVLLSIYGLHHNPKVWP 328 Query: 455 NPNKFDPDNFLPERSANRHYYAFVPFSAGPR 547 N FDP F P + +H +AF+PFS G R Sbjct: 329 NLEVFDPSRFAP--GSAQHSHAFLPFSGGSR 357 >X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-450aldo) protein. Length = 503 Score = 87.0 bits (206), Expect = 7e-17 Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 1/200 (0%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE-LDQIFGDSDRPVTF 262 +S E IK + DTTA L + + D+Q + +E L S+ P Sbjct: 299 LSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQ-- 356 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 + T E+ L L ETLRLYP + R V+ ++ L + IPAGT + + Y L R Sbjct: 357 KATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNY--HIPAGTLVQVFLYSLGRNA 414 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 ++P P +++P +L R + R+++ VPF G R C+GR+ A ++ ++L +L++F + Sbjct: 415 ALFPRPERYNPQRWLDIRGSGRNFH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF-L 472 Query: 623 ISDLKESDFKLQADIISETG 682 + L + D K+ I G Sbjct: 473 VETLTQEDIKMVYSFILRPG 492 >M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine 4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete cds. ). Length = 500 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 292 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 408 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 409 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 467 >M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. Length = 373 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 165 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 223 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 224 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 281 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 282 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 340 >D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase protein. Length = 503 Score = 87.0 bits (206), Expect = 7e-17 Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 1/200 (0%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE-LDQIFGDSDRPVTF 262 +S E IK + DTTA L + + D+Q + +E L S+ P Sbjct: 299 LSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQ-- 356 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 + T E+ L L ETLRLYP + R V+ ++ L + IPAGT + + Y L R Sbjct: 357 KATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNY--HIPAGTLVQVFLYSLGRNA 414 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 ++P P +++P +L R + R+++ VPF G R C+GR+ A ++ ++L +L++F + Sbjct: 415 ALFPRPERYNPQRWLDIRGSGRNFH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF-L 472 Query: 623 ISDLKESDFKLQADIISETG 682 + L + D K+ I G Sbjct: 473 VETLTQEDIKMVYSFILRPG 492 >DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 protein. Length = 497 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase mutant allele variant protein. Length = 566 Score = 87.0 bits (206), Expect = 7e-17 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 358 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 416 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 417 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 474 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 475 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 533 >AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to Homo sapiens cholesterol 24-hydroxylase mRNA. ). Length = 337 Score = 86.6 bits (205), Expect = 9e-17 Identities = 53/183 (28%), Positives = 97/183 (53%), Gaps = 2/183 (1%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 A DE + + T GH+T+A +F + + +I ++ E+D++ G S R + F Sbjct: 133 AQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDF 191 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 +D ++YL + L E+LRLYPP R + +E + +TY + R Sbjct: 192 EDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG------------FSTYVMGRMD 239 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILR--NF 616 + +P F+PD F P A + + + PFS G RSC+G+++A +++KV+++ +L+ F Sbjct: 240 TYFEDPLTFNPDRFGP--GAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 297 Query: 617 RVI 625 R++ Sbjct: 298 RLV 300 >Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. Length = 490 Score = 86.2 bits (204), Expect = 1e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 344 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 401 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 Query: 623 -ISDLK 637 + DLK Sbjct: 460 SVDDLK 465 >X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. Length = 497 Score = 86.2 bits (204), Expect = 1e-16 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. Length = 462 Score = 86.2 bits (204), Expect = 1e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 257 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 315 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 316 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 372 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 373 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 431 Query: 623 -ISDLK 637 + DLK Sbjct: 432 SVDDLK 437 >M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. Length = 497 Score = 86.2 bits (204), Expect = 1e-16 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE ++ V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome P-450 1 functional form mRNA, complete cds. ). Length = 490 Score = 86.2 bits (204), Expect = 1e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 344 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 401 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 Query: 623 -ISDLK 637 + DLK Sbjct: 460 SVDDLK 465 >BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 8 protein. Length = 490 Score = 86.2 bits (204), Expect = 1e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 344 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 401 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 Query: 623 -ISDLK 637 + DLK Sbjct: 460 SVDDLK 465 >AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 8 protein. Length = 490 Score = 86.2 bits (204), Expect = 1e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 344 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 401 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 Query: 623 -ISDLK 637 + DLK Sbjct: 460 SVDDLK 465 >AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 8 protein. Length = 490 Score = 86.2 bits (204), Expect = 1e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 344 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 401 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 Query: 623 -ISDLK 637 + DLK Sbjct: 460 SVDDLK 465 >X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for cytochrome P-450 (11 Beta). ). Length = 503 Score = 85.8 bits (203), Expect = 2e-16 Identities = 57/191 (29%), Positives = 97/191 (50%), Gaps = 1/191 (0%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE-LDQIFGDSDRPVTF 262 +S + IK + DTT L + + ++Q + +E L S+ P Sbjct: 299 LSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQ-- 356 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 + T E+ L L ETLRLYP + R V+ ++ L + IPAGT + + Y L R P Sbjct: 357 KATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNY--HIPAGTLVRVFLYSLGRNP 414 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 ++P P +++P +L R + R++Y VPF G R C+GR+ A ++ ++L +L++ +V Sbjct: 415 ALFPRPERYNPQRWLDIRGSGRNFY-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473 Query: 623 ISDLKESDFKL 655 L + D K+ Sbjct: 474 -ETLTQEDIKM 483 >X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120 AA) protein. Length = 210 Score = 85.8 bits (203), Expect = 2e-16 Identities = 61/186 (32%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 5 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 63 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 64 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDRE 120 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP +FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 121 -FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 179 Query: 623 -ISDLK 637 + DLK Sbjct: 180 SVDDLK 185 >BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 protein. Length = 497 Score = 85.8 bits (203), Expect = 2e-16 Identities = 52/179 (29%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D++ G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. Length = 477 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 272 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 330 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 331 HMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 387 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 388 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 447 >M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. Length = 491 Score = 85.4 bits (202), Expect = 2e-16 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = +2 Query: 62 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 241 E S + S + + ++ F G +TT+ + +M + + ++V E++Q+ G Sbjct: 275 EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP 334 Query: 242 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA 418 RP D +M Y E + E R +P+ + V Q + G IP T + + Sbjct: 335 H-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSF--RGYIIPKDTEVFLI 391 Query: 419 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 598 P + P+ F+PD+FL A + AF+PFS G R C+G A +L + + Sbjct: 392 LSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFT 451 Query: 599 TILRNFRVISDLKESDFKL 655 TIL+NF + S + D L Sbjct: 452 TILQNFSMASPVAPEDIDL 470 >M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. Length = 383 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 178 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 236 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 237 HMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 293 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 294 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 353 >M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. Length = 485 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 280 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 338 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 339 HMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 395 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455 >M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. Length = 485 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 280 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 338 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 339 HMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 395 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455 >D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. Length = 487 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 282 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 340 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 341 HMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 397 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 398 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 457 >DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2, subfamily B, polypeptide 6 protein. Length = 491 Score = 85.4 bits (202), Expect = 2e-16 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = +2 Query: 62 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 241 E S + S + + ++ F G +TT+ + +M + + ++V E++Q+ G Sbjct: 275 EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP 334 Query: 242 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA 418 RP D +M Y E + E R +P+ + V Q + G IP T + + Sbjct: 335 H-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSF--RGYIIPKDTEVFLI 391 Query: 419 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 598 P + P+ F+PD+FL A + AF+PFS G R C+G A +L + + Sbjct: 392 LSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFT 451 Query: 599 TILRNFRVISDLKESDFKL 655 TIL+NF + S + D L Sbjct: 452 TILQNFSMASPVAPEDIDL 470 >BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 protein. Length = 490 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 344 HMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 400 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460 >BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2, subfamily B, polypeptide 6 protein. Length = 491 Score = 85.4 bits (202), Expect = 2e-16 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = +2 Query: 62 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 241 E S + S + + ++ F G +TT+ + +M + + ++V E++Q+ G Sbjct: 275 EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP 334 Query: 242 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA 418 RP D +M Y E + E R +P+ + V Q + G IP T + + Sbjct: 335 H-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSF--RGYIIPKDTEVFLI 391 Query: 419 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 598 P + P+ F+PD+FL A + AF+PFS G R C+G A +L + + Sbjct: 392 LSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFT 451 Query: 599 TILRNFRVISDLKESDFKL 655 TIL+NF + S + D L Sbjct: 452 TILQNFSMASPVAPEDIDL 470 >BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2, subfamily B, polypeptide 6 protein. Length = 491 Score = 85.4 bits (202), Expect = 2e-16 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = +2 Query: 62 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 241 E S + S + + ++ F G +TT+ + +M + + ++V E++Q+ G Sbjct: 275 EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP 334 Query: 242 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA 418 RP D +M Y E + E R +P+ + V Q + G IP T + + Sbjct: 335 H-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSF--RGYIIPKDTEVFLI 391 Query: 419 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 598 P + P+ F+PD+FL A + AF+PFS G R C+G A +L + + Sbjct: 392 LSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFT 451 Query: 599 TILRNFRVISDLKESDFKL 655 TIL+NF + S + D L Sbjct: 452 TILQNFSMASPVAPEDIDL 470 >AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 protein. Length = 490 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 344 HMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 400 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460 >AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 protein. Length = 490 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 344 HMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 400 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460 >AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 protein. Length = 490 Score = 85.4 bits (202), Expect = 2e-16 Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E ++ + G +TT+ + L ++ H ++ KV EE++++ G + P QD Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPC-MQDRS 343 Query: 275 EMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA-TYKLHRRPDV 448 M Y + + E R +P + V +I IP GTT++I+ T LH + Sbjct: 344 HMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKF--RNYLIPKGTTILISLTSVLHDNKE- 400 Query: 449 YPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVIS 628 +PNP FDP +FL E + F+PFSAG R CVG A ++L + L++IL+NF + S Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460 >AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 protein. Length = 491 Score = 85.4 bits (202), Expect = 2e-16 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = +2 Query: 62 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 241 E S + S + + ++ F G +TT+ + +M + + ++V E++Q+ G Sbjct: 275 EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP 334 Query: 242 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA 418 RP D +M Y E + E R +P+ + V Q + G IP T + + Sbjct: 335 H-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSF--RGYIIPKDTEVFLI 391 Query: 419 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 598 P + P+ F+PD+FL A + AF+PFS G R C+G A +L + + Sbjct: 392 LSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFT 451 Query: 599 TILRNFRVISDLKESDFKL 655 TIL+NF + S + D L Sbjct: 452 TILQNFSMASPVAPEDIDL 470 >AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. Length = 491 Score = 85.4 bits (202), Expect = 2e-16 Identities = 54/199 (27%), Positives = 91/199 (45%), Gaps = 1/199 (0%) Frame = +2 Query: 62 ESSQSGVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGD 241 E S + S + + ++ F G +TT+ + +M + + ++V E++Q+ G Sbjct: 275 EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP 334 Query: 242 SDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIA 418 RP D +M Y E + E R +P+ + V Q + G IP T + + Sbjct: 335 H-RPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSF--RGYIIPKDTEVFLI 391 Query: 419 TYKLHRRPDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILS 598 P + P+ F+PD+FL A + AF+PFS G R C+G A +L + + Sbjct: 392 LSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFT 451 Query: 599 TILRNFRVISDLKESDFKL 655 TIL+NF + S + D L Sbjct: 452 TILQNFSMASPVAPEDIDL 470 >U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. Length = 494 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/176 (29%), Positives = 87/176 (49%), Gaps = 1/176 (0%) Frame = +2 Query: 122 IMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCL 301 + F G +T + + ++ H +++ KV EE+D++ G + +P F+D +M Y E + Sbjct: 298 LFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQP-KFEDRAKMPYTEAVI 356 Query: 302 METLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPD 478 E R +P+ +A +VN++ +P GT + R P + NP P Sbjct: 357 HEIQRFGDMLPMGLAHRVNKDTKF--RDFFLPKGTEVFPMLGSELRDPRFFSNPQDCSPQ 414 Query: 479 NFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRVISDLKESD 646 +FL E+ + AFVPFS G R C G A ++L + +TI++NFR S D Sbjct: 415 HFLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKD 470 >DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 protein. Length = 500 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 292 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 408 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 409 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 467 >DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. Length = 446 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 354 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 355 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 413 >BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family 26, subfamily B, polypeptide 1 protein. Length = 512 Score = 85.0 bits (201), Expect = 3e-16 Identities = 62/196 (31%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +2 Query: 29 KKRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 205 K L LDLL+ESS+ G ++ +E+K+ ++F + TTA+ S+ + + H + + Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320 Query: 206 KVIEELDQ--IFGDSDRPV--TFQ-DTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 367 K+ +EL I P T + DTL ++YL+ + E +RL+ P+ R V Q Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380 Query: 368 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGP 544 L +G +IP G +++ + H V+ + N FDPD F RS ++ + ++PF G Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438 Query: 545 RSCVGRKYAMLKLKVI 592 R+C+G+ A L LKV+ Sbjct: 439 RTCLGKHLAKLFLKVL 454 >BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 protein. Length = 446 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 354 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 355 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 413 >BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family 26, subfamily B, polypeptide 1 protein. Length = 512 Score = 85.0 bits (201), Expect = 3e-16 Identities = 62/196 (31%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +2 Query: 29 KKRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 205 K L LDLL+ESS+ G ++ +E+K+ ++F + TTA+ S+ + + H + + Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320 Query: 206 KVIEELDQ--IFGDSDRPV--TFQ-DTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 367 K+ +EL I P T + DTL ++YL+ + E +RL+ P+ R V Q Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380 Query: 368 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGP 544 L +G +IP G +++ + H V+ + N FDPD F RS ++ + ++PF G Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438 Query: 545 RSCVGRKYAMLKLKVI 592 R+C+G+ A L LKV+ Sbjct: 439 RTCLGKHLAKLFLKVL 454 >BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 protein. Length = 497 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 >BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. Length = 446 Score = 85.0 bits (201), Expect = 3e-16 Identities = 52/179 (29%), Positives = 93/179 (51%), Gaps = 1/179 (0%) Frame = +2 Query: 83 AISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTF 262 + +DE + V + G TT+ ++ L +M +H D+Q +V +E+D + G RP Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296 Query: 263 QDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLPSNGKKIPAGTTLVIATYKLHRR 439 D M Y + E R VP+ + +++I + G +IP GTTL+ + + Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 354 Query: 440 PDVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNF 616 V+ P +F P++FL + AF+PFSAG R+C+G A ++L + +++L++F Sbjct: 355 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 413 >AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoid metabolizing protein P450RAI-2 protein. Length = 512 Score = 85.0 bits (201), Expect = 3e-16 Identities = 62/196 (31%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +2 Query: 29 KKRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 205 K L LDLL+ESS+ G ++ +E+K+ ++F + TTA+ S+ + + H + + Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320 Query: 206 KVIEELDQ--IFGDSDRPV--TFQ-DTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 367 K+ +EL I P T + DTL ++YL+ + E +RL+ P+ R V Q Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380 Query: 368 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGP 544 L +G +IP G +++ + H V+ + N FDPD F RS ++ + ++PF G Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438 Query: 545 RSCVGRKYAMLKLKVI 592 R+C+G+ A L LKV+ Sbjct: 439 RTCLGKHLAKLFLKVL 454 >AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. Length = 512 Score = 85.0 bits (201), Expect = 3e-16 Identities = 62/196 (31%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +2 Query: 29 KKRLAFLDLLLESSQS-GVAISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQD 205 K L LDLL+ESS+ G ++ +E+K+ ++F + TTA+ S+ + + H + + Sbjct: 261 KDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320 Query: 206 KVIEELDQ--IFGDSDRPV--TFQ-DTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 367 K+ +EL I P T + DTL ++YL+ + E +RL+ P+ R V Q Sbjct: 321 KLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFE 380 Query: 368 LPSNGKKIPAGTTLVIATYKLHRRPDVYPNPNKFDPDNFLPERSANRH-YYAFVPFSAGP 544 L +G +IP G +++ + H V+ + N FDPD F RS ++ + ++PF G Sbjct: 381 L--DGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGV 438 Query: 545 RSCVGRKYAMLKLKVI 592 R+C+G+ A L LKV+ Sbjct: 439 RTCLGKHLAKLFLKVL 454 >M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9. ). Length = 503 Score = 84.6 bits (200), Expect = 3e-16 Identities = 60/200 (30%), Positives = 98/200 (49%), Gaps = 1/200 (0%) Frame = +2 Query: 86 ISDEEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEE-LDQIFGDSDRPVTF 262 +S E IK + DTTA L + + D+Q + +E L S+ P Sbjct: 299 LSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEHPQ-- 356 Query: 263 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 442 + T E+ L L ETLRLYP + R V+ ++ L + IPAGT + + Y L R Sbjct: 357 KATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNY--HIPAGTLVQVFLYSLGRNA 414 Query: 443 DVYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV 622 ++P P +++P +L R + R+ + VPF G R C+GR+ A ++ ++L +L+ F + Sbjct: 415 ALFPRPERYNPQRWLDIRGSGRNLH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKRF-L 472 Query: 623 ISDLKESDFKLQADIISETG 682 + L + D K+ I G Sbjct: 473 VETLTQEDIKMVYSFILRPG 492 >M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. Length = 480 Score = 84.6 bits (200), Expect = 3e-16 Identities = 61/186 (32%), Positives = 92/186 (49%), Gaps = 5/186 (2%) Frame = +2 Query: 95 EEIKEQVDTIMFEGHDTTAAGSSFFLSMMGIHQDIQDKVIEELDQIFGDSDRPVTFQDTL 274 E + V + G +TT+ + L ++ H ++ KV EE+D + G P QD Sbjct: 275 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC-MQDRS 333 Query: 275 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKK--IPAGTTLV-IATYKLHRRPD 445 M Y + + E R VP V +T + + IP GTT++ + T LH + Sbjct: 334 HMPYTDAVVHEIQRYSDLVPT---GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 390 Query: 446 VYPNPNKFDPDNFLPERSANRHYYAFVPFSAGPRSCVGRKYAMLKLKVILSTILRNFRV- 622 +PNPN FDP FL + + F+PFSAG R C G A ++L + L+TIL+NF + Sbjct: 391 -FPNPNIFDPGLFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 449 Query: 623 -ISDLK 637 + DLK Sbjct: 450 SVDDLK 455 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 116,473,315 Number of Sequences: 237096 Number of extensions: 2629595 Number of successful extensions: 6546 Number of sequences better than 10.0: 439 Number of HSP's better than 10.0 without gapping: 5679 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5946 length of database: 76,859,062 effective HSP length: 89 effective length of database: 55,757,518 effective search space used: 9255747988 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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