Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0343
(806 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 83 9e-16
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 83 9e-16
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 83 9e-16
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 83 9e-16
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 83 9e-16
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 83 9e-16
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 83 9e-16
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 83 9e-16
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 83 9e-16
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 83 9e-16
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 71 7e-12
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 71 7e-12
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 71 7e-12
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 71 7e-12
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 70 9e-12
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 70 1e-11
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 69 2e-11
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 69 2e-11
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 69 3e-11
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 69 3e-11
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 69 3e-11
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 69 3e-11
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 68 3e-11
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 68 3e-11
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 68 3e-11
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 68 3e-11
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 68 3e-11
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 68 3e-11
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 68 3e-11
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 68 3e-11
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 68 3e-11
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 68 3e-11
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 67 8e-11
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 66 1e-10
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 66 1e-10
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 66 1e-10
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 65 3e-10
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 64 4e-10
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 64 4e-10
M74055-1|AAA36742.1| 229|Homo sapiens thromboxane synthase prot... 64 4e-10
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 64 4e-10
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 64 6e-10
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 64 6e-10
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 63 1e-09
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 57 7e-08
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 57 9e-08
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 57 9e-08
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 46 1e-04
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 46 1e-04
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 46 1e-04
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 46 2e-04
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 46 2e-04
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 46 2e-04
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 44 6e-04
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 42 0.003
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 41 0.006
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 41 0.006
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 41 0.006
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 41 0.006
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 41 0.006
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 40 0.011
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 40 0.011
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 40 0.014
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 40 0.014
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 40 0.014
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 40 0.014
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 40 0.014
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 40 0.014
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 40 0.014
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 39 0.024
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 39 0.024
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 38 0.043
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 38 0.043
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 38 0.043
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 38 0.043
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 38 0.043
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 38 0.043
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 38 0.043
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 38 0.043
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 38 0.043
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 38 0.043
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 38 0.043
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 38 0.043
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 38 0.043
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 38 0.056
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 37 0.075
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 37 0.075
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 37 0.075
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 37 0.075
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 37 0.075
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 37 0.075
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 37 0.075
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 36 0.13
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 36 0.13
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 36 0.17
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 36 0.17
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 36 0.17
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 36 0.17
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 36 0.23
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 36 0.23
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 35 0.30
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.30
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.30
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.30
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.30
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.30
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 35 0.30
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 35 0.40
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 35 0.40
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 35 0.40
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 35 0.40
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 34 0.53
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 33 0.92
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 33 0.92
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 33 1.2
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 33 1.2
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 33 1.2
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 33 1.6
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 33 1.6
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 33 1.6
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 33 1.6
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 33 1.6
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 32 2.1
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 32 2.1
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 32 2.1
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 32 2.1
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 31 3.7
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 31 4.9
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 31 4.9
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 31 4.9
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 31 4.9
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 31 4.9
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 31 4.9
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 31 4.9
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 31 4.9
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 31 4.9
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 31 4.9
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 31 4.9
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 31 4.9
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 31 4.9
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 31 4.9
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 31 4.9
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 31 4.9
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 31 4.9
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 31 4.9
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 31 6.5
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 31 6.5
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 31 6.5
BC043005-1|AAH43005.2| 794|Homo sapiens MGC39581 protein protein. 31 6.5
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 30 8.6
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 83.4 bits (197), Expect = 9e-16
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANG 374
+ G + G +P LV+ +P++IK V K+ Y + + + L FA
Sbjct: 71 MW------GLYEGQQPMLVIMDPDMIKTVLVKECYSVFT-NQMPLGPMGFLKSALSFAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S+K K M ++ +C L L +E ++ + I ++ YT+D
Sbjct: 124 EEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDV 183
Query: 555 ICSSAFGIESNTL 593
I + FG+ ++L
Sbjct: 184 ITGTLFGVNLDSL 196
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVT 179
+V + A L++ Y+Y TR +KR +P P+P GN + Y L + +
Sbjct: 8 AVETWLLLAVSLVLLYLY--GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECY 65
Query: 180 QKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNL 359
+K + + G++ G P L + +P++I+ V K+ Y + S + +
Sbjct: 66 KKYGKMW------GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRS-LGPVGFMKSAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K MF ++ + L L +E + + + ++
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I ++FG+ ++L
Sbjct: 179 YSMDVITGTSFGVNIDSL 196
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVT 179
+V + A L++ Y+Y TR +KR +P P+P GN + Y L + +
Sbjct: 8 AVETWLLLAVSLVLLYLY--GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECY 65
Query: 180 QKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNL 359
+K + + G++ G P L + +P++I+ V K+ Y + S + +
Sbjct: 66 KKYGKMW------GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRS-LGPVGFMKSAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K MF ++ + L L +E + + + ++
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I ++FG+ ++L
Sbjct: 179 YSMDVITGTSFGVNIDSL 196
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVT 179
+V + A L++ Y+Y TR +KR +P P+P GN + Y L + +
Sbjct: 8 AVETWLLLAVSLVLLYLY--GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECY 65
Query: 180 QKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNL 359
+K + + G++ G P L + +P++I+ V K+ Y + S + +
Sbjct: 66 KKYGKMW------GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRS-LGPVGFMKSAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K MF ++ + L L +E + + + ++
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I ++FG+ ++L
Sbjct: 179 YSMDVITGTSFGVNIDSL 196
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 70.5 bits (165), Expect = 7e-12
Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVT 179
+V + A L++ Y+Y TR +KR +P P+P GN + Y L + +
Sbjct: 8 AVETWLLLAVSLVLLYLY--GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECY 65
Query: 180 QKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNL 359
+K + + G++ G P L + +P++I+ V K+ Y + S + +
Sbjct: 66 KKYGKMW------GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRS-LGPVGFMKSAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K MF ++ + L L +E + + + ++
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I ++FG+ ++L
Sbjct: 179 YSMDVITGTSFGVNIDSL 196
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 70.1 bits (164), Expect = 9e-12
Identities = 48/198 (24%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVT 179
+V + A L++ Y+Y TR +KR +P P+P GN + Y L + +
Sbjct: 8 AVETWLLLAVSLVLLYLY--GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECY 65
Query: 180 QKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNL 359
+K + + G++ G P L + +P++I+ V K+ Y + S + +
Sbjct: 66 KKYGKMW------GTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRS-LGPVGFMKSAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K MF ++ + L L +E + + + ++
Sbjct: 119 SLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I ++FG+ ++L
Sbjct: 179 YSMDVITGTSFGVNIDSL 196
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/193 (25%), Positives = 95/193 (49%), Gaps = 1/193 (0%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQ 197
V A L++ YIY T +K+ +P P+PF GN + Y + + + C +
Sbjct: 13 VLVATSLVLLYIY--GTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHK 66
Query: 198 FPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANG 374
+ +G + G +P L + +P++IK V K+ Y F +R + + + A
Sbjct: 67 KYGK-VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAED 123
Query: 375 DKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDS 554
++WK +R L+P F+S K+K M ++ + L L +E + + + ++ Y++D
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183
Query: 555 ICSSAFGIESNTL 593
I S++FG+ ++L
Sbjct: 184 ITSTSFGVNIDSL 196
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 69.3 bits (162), Expect = 2e-11
Identities = 45/182 (24%), Positives = 91/182 (50%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R+ + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKLVLVKECYSVFTNRE--PFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I SS+FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFGVNVD 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 69.3 bits (162), Expect = 2e-11
Identities = 45/182 (24%), Positives = 91/182 (50%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R+ + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKLVLVKECYSVFTNRE--PFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I SS+FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFGVNVD 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/198 (23%), Positives = 97/198 (48%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V + A L++ Y+Y TR +K+ +P P+PF GN + + +
Sbjct: 8 AVETWLLLAVSLILLYLY--GTRTHGLFKKLGIPGPTPLPFLGNALSF---RKGYWTFDM 62
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNL 359
+ +++ R +G + +P L + +P++IK V K+ Y F +R + + +
Sbjct: 63 ECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K M ++ + L L +E + + + ++
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I S++FG+ ++L
Sbjct: 179 YSMDVITSTSFGVSIDSL 196
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/198 (23%), Positives = 97/198 (48%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V + A L++ Y+Y TR +K+ +P P+PF GN + + +
Sbjct: 8 AVETWLLLAVSLILLYLY--GTRTHGLFKKLGIPGPTPLPFLGNALSF---RKGYWTFDM 62
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNL 359
+ +++ R +G + +P L + +P++IK V K+ Y F +R + + +
Sbjct: 63 ECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K M ++ + L L +E + + + ++
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I S++FG+ ++L
Sbjct: 179 YSMDVITSTSFGVSIDSL 196
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/198 (23%), Positives = 97/198 (48%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V + A L++ Y+Y TR +K+ +P P+PF GN + + +
Sbjct: 8 AVETWLLLAVSLILLYLY--GTRTHGLFKKLGIPGPTPLPFLGNALSF---RKGYWTFDM 62
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNL 359
+ +++ R +G + +P L + +P++IK V K+ Y F +R + + +
Sbjct: 63 ECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K M ++ + L L +E + + + ++
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I S++FG+ ++L
Sbjct: 179 YSMDVITSTSFGVSIDSL 196
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 68.5 bits (160), Expect = 3e-11
Identities = 47/198 (23%), Positives = 97/198 (48%), Gaps = 1/198 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V + A L++ Y+Y TR +K+ +P P+PF GN + + +
Sbjct: 8 AVETWLLLAVSLILLYLY--GTRTHGLFKKLGIPGPTPLPFLGNALSF---RKGYWTFDM 62
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNL 359
+ +++ R +G + +P L + +P++IK V K+ Y F +R + + +
Sbjct: 63 ECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAI 118
Query: 360 FFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIR 539
A ++WK +R L+P F+S K+K M ++ + L L +E + + + ++
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 540 YTLDSICSSAFGIESNTL 593
Y++D I S++FG+ ++L
Sbjct: 179 YSMDVITSTSFGVSIDSL 196
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 68.1 bits (159), Expect = 3e-11
Identities = 44/182 (24%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + +G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSY--HKGFC--MFDMECHKKYGK-VWGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 66.9 bits (156), Expect = 8e-11
Identities = 44/182 (24%), Positives = 89/182 (48%), Gaps = 1/182 (0%)
Frame = +3
Query: 51 IYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFY 230
+Y + T +K+ +P P+PF GN + Y + + + C + + G +
Sbjct: 22 LYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFC--MFDMECHKKYGK-VCGFYD 76
Query: 231 GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLT 407
G +P L + +P++IK V K+ Y F +R + + + A ++WK +R L+
Sbjct: 77 GQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLS 134
Query: 408 PLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ +
Sbjct: 135 PTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
Query: 588 TL 593
+L
Sbjct: 195 SL 196
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/184 (26%), Positives = 82/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 19 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLYG 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V LF + +W
Sbjct: 76 --PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRD-KRW 132
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 133 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 192
Query: 564 SAFG 575
AFG
Sbjct: 193 VAFG 196
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/184 (26%), Positives = 82/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLYG 76
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V LF + +W
Sbjct: 77 --PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRD-KRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
AFG
Sbjct: 194 VAFG 197
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/184 (26%), Positives = 82/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLYG 76
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V LF + +W
Sbjct: 77 --PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRD-KRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
AFG
Sbjct: 194 VAFG 197
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.9 bits (151), Expect = 3e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase
protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>M74055-1|AAA36742.1| 229|Homo sapiens thromboxane synthase
protein.
Length = 229
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 4 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 59
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 60 -GPLCGYYLGRRMFIVISEPDMIKQVLVQNFSNFTNRMASGLEFKS-VADSVLFLRDKRW 117
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 118 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 177
Query: 564 SAFG 575
FG
Sbjct: 178 VPFG 181
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase
protein.
Length = 441
Score = 64.1 bits (149), Expect = 6e-10
Identities = 47/184 (25%), Positives = 81/184 (44%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKVNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VRFG 197
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.1 bits (149), Expect = 6e-10
Identities = 47/184 (25%), Positives = 80/184 (43%)
Frame = +3
Query: 24 AAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFP 203
A V L+ + ++ST F ++ + + KP PF GN + + +L + +
Sbjct: 20 ALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFF---HQGFWESQMELRKLY- 75
Query: 204 DRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKW 383
P G + G +V+ P++IKQV ++F F +R S K V ++ F +W
Sbjct: 76 -GPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKS-VADSVLFLRDKRW 133
Query: 384 KVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICS 563
+ VR L FS K+ M L+ + L L + + +I+ YT D + S
Sbjct: 134 EEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVAS 193
Query: 564 SAFG 575
FG
Sbjct: 194 VPFG 197
>AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 62.9 bits (146), Expect = 1e-09
Identities = 46/172 (26%), Positives = 76/172 (44%)
Frame = +3
Query: 60 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTE 239
+ST F ++ + + KP PF GN + + + +L + + P G + G
Sbjct: 1 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF---RQGFWESQMELRKLYG--PLCGYYLGRR 55
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFS 419
+V+ P++IKQV ++F F +R S K V LF + +W+ VR L FS
Sbjct: 56 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRD-KRWEEVRGALMSAFS 114
Query: 420 SLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFG 575
K+ M L+ + L L + + +I+ YT D + S AFG
Sbjct: 115 PEKLNEMVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG 166
>AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein.
Length = 311
Score = 57.2 bits (132), Expect = 7e-08
Identities = 36/122 (29%), Positives = 55/122 (45%)
Frame = +3
Query: 210 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKV 389
P G + G +V+ P++IKQV ++F F +R S K V LF + +W+
Sbjct: 9 PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRD-KRWEE 67
Query: 390 VRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSA 569
VR L FS K+ M L+ + L L + + +I+ YT D + S A
Sbjct: 68 VRGALMSAFSPEKLNEMVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVA 127
Query: 570 FG 575
FG
Sbjct: 128 FG 129
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 56.8 bits (131), Expect = 9e-08
Identities = 36/122 (29%), Positives = 55/122 (45%)
Frame = +3
Query: 210 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKV 389
P G + G +V+ P++IKQV ++F F +R S K V LF + +W+
Sbjct: 9 PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRD-KRWEE 67
Query: 390 VRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSA 569
VR L FS K+ M L+ + L L + + +I+ YT D + S A
Sbjct: 68 VRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVA 127
Query: 570 FG 575
FG
Sbjct: 128 FG 129
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 56.8 bits (131), Expect = 9e-08
Identities = 34/125 (27%), Positives = 66/125 (52%), Gaps = 2/125 (1%)
Frame = +3
Query: 225 FY-GTEPALVLQNPEIIKQVFTKDFY-YFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
FY G +P L + +P++IK V K+ Y F +R + + + A ++WK +R
Sbjct: 1 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRS 58
Query: 399 NLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGI 578
L+P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+
Sbjct: 59 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 118
Query: 579 ESNTL 593
++L
Sbjct: 119 NIDSL 123
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++++ +S + +RK P P+P GN ++ DV + +C+ F
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQI--------DV-KDICKSF 54
Query: 201 PD-----RPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFF 365
+ P F ++G P +V E +K+ + F+ R NS + + +
Sbjct: 55 TNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS 114
Query: 366 ANGDKWKVVRQ-NLTPL 413
+NG +WK +R+ +LT L
Sbjct: 115 SNGKRWKEIRRFSLTTL 131
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++++ +S + +RK P P+P GN ++ DV + +C+ F
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQI--------DV-KDICKSF 54
Query: 201 PD-----RPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFF 365
+ P F ++G P +V E +K+ + F+ R NS + + +
Sbjct: 55 TNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS 114
Query: 366 ANGDKWKVVRQ-NLTPL 413
+NG +WK +R+ +LT L
Sbjct: 115 SNGKRWKEIRRFSLTTL 131
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++++ +S + +RK P P+P GN ++ DV + +C+ F
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQI--------DV-KDICKSF 54
Query: 201 PD-----RPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFF 365
+ P F ++G P +V E +K+ + F+ R NS + + +
Sbjct: 55 TNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS 114
Query: 366 ANGDKWKVVRQ-NLTPL 413
+NG +WK +R+ +LT L
Sbjct: 115 SNGKRWKEIRRFSLTTL 131
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++++ +S + +RK P P+P GN ++ DV + +C+ F
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQI--------DV-KDICKSF 54
Query: 201 PD-----RPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFF 365
+ P F ++G P +V E +K+ + F+ R NS + + +
Sbjct: 55 TNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS 114
Query: 366 ANGDKWKVVRQ-NLTPL 413
+NG +WK +R+ +LT L
Sbjct: 115 SNGKRWKEIRRFSLTNL 131
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++++ +S + +RK P P+P GN ++ DV + +C+ F
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQI--------DV-KDICKSF 54
Query: 201 PD-----RPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFF 365
+ P F ++G P +V E +K+ + F+ R NS + + +
Sbjct: 55 TNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS 114
Query: 366 ANGDKWKVVRQ-NLTPL 413
+NG +WK +R+ +LT L
Sbjct: 115 SNGKRWKEIRRFSLTNL 131
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++++ +S + +RK P P+P GN ++ DV + +C+ F
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQI--------DV-KDICKSF 54
Query: 201 PD-----RPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFF 365
+ P F ++G P +V E +K+ + F+ R NS + + +
Sbjct: 55 TNFSKVYGPVFTVYFGMNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIIS 114
Query: 366 ANGDKWKVVRQ-NLTPL 413
+NG +WK +R+ +LT L
Sbjct: 115 SNGKRWKEIRRFSLTTL 131
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Frame = +3
Query: 18 VFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVTQKLCQ 194
V A L++ YIY T +K+ +P P+PF G + Y+ L ++ + +K +
Sbjct: 13 VLVATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGE 70
Query: 195 QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY 299
+G + G +P LV+ +P++IK V K+ Y
Sbjct: 71 M------WGLYEGQQPMLVIMDPDMIKTVLVKECY 99
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 41.5 bits (93), Expect = 0.003
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Frame = +3
Query: 87 KRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPD-----RPYFGSFYGTEPALV 251
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 16 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 66
Query: 252 LQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ-NLTPL 413
E +K+ + F+ R NS + + + +NG +WK +R+ +LT L
Sbjct: 67 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 121
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.006
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++ + S + + K P P+P GN LQ I DV++ L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNI-----LQIDIKDVSKSLTNLS 58
Query: 201 PDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGD 377
P F ++G E +VL E++K+ F+ R + + + F+NG
Sbjct: 59 KIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGK 118
Query: 378 KWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIR 524
+WK +R+ FS + ++N F + ++ S+ED + +E + L + E+R
Sbjct: 119 RWKEIRR-----FSLMTLRN-FGMGKR---SIEDRVQEEARCL-VEELR 157
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 40.7 bits (91), Expect = 0.006
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++ + S + + K P P+P GN LQ I DV++ L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNI-----LQIDIKDVSKSLTNLS 58
Query: 201 PDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGD 377
P F ++G E +VL E++K+ F+ R + + + F+NG
Sbjct: 59 KIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGK 118
Query: 378 KWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIR 524
+WK +R+ FS + ++N F + ++ S+ED + +E + L + E+R
Sbjct: 119 RWKEIRR-----FSLMTLRN-FGMGKR---SIEDRVQEEARCL-VEELR 157
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.006
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++ + S + + K P P+P GN LQ I DV++ L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNI-----LQIDIKDVSKSLTNLS 58
Query: 201 PDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGD 377
P F ++G E +VL E++K+ F+ R + + + F+NG
Sbjct: 59 KIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGK 118
Query: 378 KWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIR 524
+WK +R+ FS + ++N F + ++ S+ED + +E + L + E+R
Sbjct: 119 RWKEIRR-----FSLMTLRN-FGMGKR---SIEDRVQEEARCL-VEELR 157
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.006
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++ + S + + K P P+P GN LQ I DV++ L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNI-----LQIDIKDVSKSLTNLS 58
Query: 201 PDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGD 377
P F ++G E +VL E++K+ F+ R + + + F+NG
Sbjct: 59 KIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGK 118
Query: 378 KWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIR 524
+WK +R+ FS + ++N F + ++ S+ED + +E + L + E+R
Sbjct: 119 RWKEIRR-----FSLMTLRN-FGMGKR---SIEDRVQEEARCL-VEELR 157
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 40.7 bits (91), Expect = 0.006
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 1/169 (0%)
Frame = +3
Query: 21 FAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQF 200
F VL ++ + S + + K P P+P GN LQ I DV++ L
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNI-----LQIDIKDVSKSLTNLS 58
Query: 201 PDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGD 377
P F ++G E +VL E++K+ F+ R + + + F+NG
Sbjct: 59 KIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGK 118
Query: 378 KWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIR 524
+WK +R+ FS + ++N F + ++ S+ED + +E + L + E+R
Sbjct: 119 RWKEIRR-----FSLMTLRN-FGMGKR---SIEDRVQEEARCL-VEELR 157
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 39.9 bits (89), Expect = 0.011
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 7/137 (5%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPD-----RPYFGSFYGTEPALVLQNPE 266
P P+P GN ++ DV + +C+ F + P F ++G P +V E
Sbjct: 3 PGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYE 53
Query: 267 IIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ-NLTPLFS-SLKMKNM 440
+K+ + F+ R NS + + + +NG +WK +R+ +LT L + + +++
Sbjct: 54 AVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSI 113
Query: 441 FYLVEKCNHSLEDMLDK 491
V++ H L D L K
Sbjct: 114 EDRVQEEAHCLVDELRK 130
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 39.9 bits (89), Expect = 0.011
Identities = 26/100 (26%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSYIGDVT 179
+V + A L++ Y+Y TR +KR +P P+P GN + Y L + +
Sbjct: 8 AVETWLLLAVSLVLLYLY--GTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECY 65
Query: 180 QKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFY 299
+K + +G++ G P L + +P++I+ V K+ Y
Sbjct: 66 KKYGKM------WGTYEGQLPVLAITDPDVIRTVLVKECY 99
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPAWKDIRRFSLTTL 133
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 39.5 bits (88), Expect = 0.014
Identities = 38/138 (27%), Positives = 67/138 (48%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F + G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 38.7 bits (86), Expect = 0.024
Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 2/127 (1%)
Frame = +3
Query: 234 TEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTP 410
T P L+L +P+II+ + T +D Y K + L + GDKW R+ LTP
Sbjct: 95 TFPLLILCHPDIIRPI-TSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
Query: 411 LFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQI-IEIRSAMIRYTLDSICSSAFGIESN 587
F +K + K + + D + + +++ + TLDS+ F ESN
Sbjct: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
Query: 588 TLREGGE 608
+ E
Sbjct: 214 CQEKPSE 220
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 38.7 bits (86), Expect = 0.024
Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 2/127 (1%)
Frame = +3
Query: 234 TEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTP 410
T P L+L +P+II+ + T +D Y K + L + GDKW R+ LTP
Sbjct: 95 TFPLLILCHPDIIRPI-TSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
Query: 411 LFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQI-IEIRSAMIRYTLDSICSSAFGIESN 587
F +K + K + + D + + +++ + TLDS+ F ESN
Sbjct: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
Query: 588 TLREGGE 608
+ E
Sbjct: 214 CQEKPSE 220
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 18 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 72
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 73 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 126
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 127 ---SIEDRVQEEARCL-VEELR 144
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 26 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 80
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 81 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 134
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 135 ---SIEDRVQEEARCL-VEELR 152
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 26 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 80
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 81 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 134
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 135 ---SIEDRVQEEARCL-VEELR 152
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDRVQEEARCL-VEELR 157
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 37.9 bits (84), Expect = 0.043
Identities = 31/132 (23%), Positives = 57/132 (43%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
S+S + + LV + S+R K K P +P+P GN + + Q + +T
Sbjct: 3 SISTAILLLLLALVCLLLTLSSRD----KGKLPPGPRPLPILGNLL-LLCSQDMLTSLT- 56
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
KL +++ + G +VL + +K+ F+ R + +
Sbjct: 57 KLSKEYGSM--YTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIA 114
Query: 363 FANGDKWKVVRQ 398
F++GD+WKV+RQ
Sbjct: 115 FSSGDRWKVLRQ 126
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 28 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 82
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 83 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 136
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 137 ---SIEDRVQEEARCL-VEELR 154
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDRVQEEARCL-VEELR 157
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDCVQEEARCL-VEELR 157
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDRVQEEARCL-VEELR 157
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDRVQEEARCL-VEELR 157
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDRVQEEARCL-VEELR 157
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R + K + F+NG +WK +R+
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 37.9 bits (84), Expect = 0.043
Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 278
P P+P GN LQ I D+++ L P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNI-----LQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKE 85
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEK 458
F+ R + + F+NG KWK +R+ FS + ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 459 CNHSLEDMLDKEIKDLQIIEIR 524
S+ED + +E + L + E+R
Sbjct: 140 ---SIEDRVQEEARCL-VEELR 157
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 37.5 bits (83), Expect = 0.056
Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
+V+ LV+AAF+LLV+ W + W P+ P+P GN + + L++ T
Sbjct: 7 TVALLVWAAFLLLVS---MW-RQVHSSWNLPPGPF--PLPIIGNLFQ-LELKNIPKSFT- 58
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
+L Q+F P F G++ +V+ + +K+ F+ R + H + +
Sbjct: 59 RLAQRF--GPVFTLCVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAH-RDRGII 115
Query: 363 FANGDKWKVVRQ-NLTPL 413
F NG WK +R+ +LT L
Sbjct: 116 FNNGPTWKDIRRFSLTTL 133
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 37.1 bits (82), Expect = 0.075
Identities = 29/130 (22%), Positives = 56/130 (43%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A ++ +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 36.3 bits (80), Expect = 0.13
Identities = 35/145 (24%), Positives = 71/145 (48%), Gaps = 1/145 (0%)
Frame = +3
Query: 93 KNVPYAKPVPFFGNYMRYITLQSYIGD-VTQKLCQQFPDRPYFGSFYGTEPALVLQNPEI 269
KN P + + ++R TL+ ++Q+L + + P F ++G E +VL E+
Sbjct: 3 KNSPTQRCLTLATFWIRVATLRKVTTSCLSQQLSKIYG--PVFTLYFGLERMVVLHGYEV 60
Query: 270 IKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYL 449
+K+ F+ R + + + F+NG +WK +R+ FS + ++N F +
Sbjct: 61 VKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGM 114
Query: 450 VEKCNHSLEDMLDKEIKDLQIIEIR 524
++ S+ED + +E + L + E+R
Sbjct: 115 GKR---SIEDRVQEEARCL-VEELR 135
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 36.3 bits (80), Expect = 0.13
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F R + K + F+NG +WK +R+
Sbjct: 90 HGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 35.9 bits (79), Expect = 0.17
Identities = 38/170 (22%), Positives = 69/170 (40%), Gaps = 3/170 (1%)
Frame = +3
Query: 192 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFA 368
+++ P + G P + L N E ++ + T S S Y E + L +
Sbjct: 82 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKS---SMYKFLEPWLGLGLLTS 138
Query: 369 NGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTL 548
G+KW+ R+ LTP F +++ ++ + + L L+K I + + L
Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197
Query: 549 DSICSSAFGIESNTLREGGENSPFANMGSIVFSSSITRGLK--WISRSMW 692
D IC +A G N + ++S + S I R +K W+ +W
Sbjct: 198 DIICETAMG--KNIGAQSNDDSEYVR-AVYRMSEMIFRRIKMPWLWLDLW 244
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 35.9 bits (79), Expect = 0.17
Identities = 38/170 (22%), Positives = 69/170 (40%), Gaps = 3/170 (1%)
Frame = +3
Query: 192 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFA 368
+++ P + G P + L N E ++ + T S S Y E + L +
Sbjct: 82 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKS---SMYKFLEPWLGLGLLTS 138
Query: 369 NGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTL 548
G+KW+ R+ LTP F +++ ++ + + L L+K I + + L
Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197
Query: 549 DSICSSAFGIESNTLREGGENSPFANMGSIVFSSSITRGLK--WISRSMW 692
D IC +A G N + ++S + S I R +K W+ +W
Sbjct: 198 DIICETAMG--KNIGAQSNDDSEYVR-AVYRMSEMIFRRIKMPWLWLDLW 244
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 35.9 bits (79), Expect = 0.17
Identities = 38/170 (22%), Positives = 69/170 (40%), Gaps = 3/170 (1%)
Frame = +3
Query: 192 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFA 368
+++ P + G P + L N E ++ + T S S Y E + L +
Sbjct: 60 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKS---SMYKFLEPWLGLGLLTS 116
Query: 369 NGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTL 548
G+KW+ R+ LTP F +++ ++ + + L L+K I + + L
Sbjct: 117 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 175
Query: 549 DSICSSAFGIESNTLREGGENSPFANMGSIVFSSSITRGLK--WISRSMW 692
D IC +A G N + ++S + S I R +K W+ +W
Sbjct: 176 DIICETAMG--KNIGAQSNDDSEYVR-AVYRMSEMIFRRIKMPWLWLDLW 222
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 35.9 bits (79), Expect = 0.17
Identities = 38/170 (22%), Positives = 69/170 (40%), Gaps = 3/170 (1%)
Frame = +3
Query: 192 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFA 368
+++ P + G P + L N E ++ + T S S Y E + L +
Sbjct: 82 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKS---SMYKFLEPWLGLGLLTS 138
Query: 369 NGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTL 548
G+KW+ R+ LTP F +++ ++ + + L L+K I + + L
Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197
Query: 549 DSICSSAFGIESNTLREGGENSPFANMGSIVFSSSITRGLK--WISRSMW 692
D IC +A G N + ++S + S I R +K W+ +W
Sbjct: 198 DIICETAMG--KNIGAQSNDDSEYVR-AVYRMSEMIFRRIKMPWLWLDLW 244
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 35.5 bits (78), Expect = 0.23
Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 2/130 (1%)
Frame = +3
Query: 15 LVFAAFVLLVTYIYY--WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
L+ A V L + W RK K K P P+PF GNY++ T Q Y + K+
Sbjct: 2 LLVALLVCLTVMVLMSVWQQRKN---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 56
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 57 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 114
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 115 NGERAKQLRR 124
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 35.5 bits (78), Expect = 0.23
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 1/94 (1%)
Frame = +3
Query: 114 PVPFFGNYMRYITLQSYIGDVTQKLCQ-QFPDRPYFGSFYGTEPALVLQNPEIIKQVFTK 290
P+P GN LQ + D+++ L P F ++G +P +VL E +K+
Sbjct: 35 PLPIIGNI-----LQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALID 89
Query: 291 DFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVV 392
F+ R + K + F+NG +WK +
Sbjct: 90 HGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEI 123
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.30
Identities = 29/130 (22%), Positives = 54/130 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ + +T + S + + K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +K+ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFS 119
Query: 369 NGDKWKVVRQ 398
NG++ K +R+
Sbjct: 120 NGERAKQLRR 129
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.40
Identities = 30/132 (22%), Positives = 56/132 (42%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
S+S + + LV + S+R K K P +P+ GN + + Q + +T
Sbjct: 3 SISTAILLLLLALVCLLLTLSSRD----KGKLPPGPRPLSILGNLL-LLCSQDMLTSLT- 56
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
KL +++ + G +VL + +K+ F+ R + +
Sbjct: 57 KLSKEYGSM--YTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIA 114
Query: 363 FANGDKWKVVRQ 398
F++GD+WKV+RQ
Sbjct: 115 FSSGDRWKVLRQ 126
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.40
Identities = 30/132 (22%), Positives = 56/132 (42%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
S+S + + LV + S+R K K P +P+ GN + + Q + +T
Sbjct: 3 SISTAILLLLLALVCLLLTLSSRD----KGKLPPGPRPLSILGNLL-LLCSQDMLTSLT- 56
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
KL +++ + G +VL + +K+ F+ R + +
Sbjct: 57 KLSKEYGSM--YTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIA 114
Query: 363 FANGDKWKVVRQ 398
F++GD+WKV+RQ
Sbjct: 115 FSSGDRWKVLRQ 126
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 34.7 bits (76), Expect = 0.40
Identities = 30/132 (22%), Positives = 56/132 (42%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
S+S + + LV + S+R K K P +P+ GN + + Q + +T
Sbjct: 3 SISTAILLLLLALVCLLLTLSSRD----KGKLPPGPRPLSILGNLL-LLCSQDMLTSLT- 56
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
KL +++ + G +VL + +K+ F+ R + +
Sbjct: 57 KLSKEYGSM--YTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIA 114
Query: 363 FANGDKWKVVRQ 398
F++GD+WKV+RQ
Sbjct: 115 FSSGDRWKVLRQ 126
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 34.7 bits (76), Expect = 0.40
Identities = 30/132 (22%), Positives = 56/132 (42%)
Frame = +3
Query: 3 SVSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQ 182
S+S + + LV + S+R K K P +P+ GN + + Q + +T
Sbjct: 3 SISTAILLLLLALVCLLLTLSSRD----KGKLPPGPRPLSILGNLL-LLCSQDMLTSLT- 56
Query: 183 KLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLF 362
KL +++ + G +VL + +K+ F+ R + +
Sbjct: 57 KLSKEYGSM--YTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIA 114
Query: 363 FANGDKWKVVRQ 398
F++GD+WKV+RQ
Sbjct: 115 FSSGDRWKVLRQ 126
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 34.3 bits (75), Expect = 0.53
Identities = 28/126 (22%), Positives = 52/126 (41%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S ++ A + +T + S + K K P P+PF GNY++ T Q Y + K+
Sbjct: 4 SGMLLVALLACLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKI 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+++ P F G +VL + +++ F+ R + F+
Sbjct: 62 SERY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFS 119
Query: 369 NGDKWK 386
NG++ K
Sbjct: 120 NGERAK 125
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 33.5 bits (73), Expect = 0.92
Identities = 37/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLV 452
++ + F+ R + FANG++WKV+R+ FS M++
Sbjct: 85 REALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRR-----FSVTTMRDFGMGK 139
Query: 453 EKCNHSLEDMLDKEIKDLQ-----IIEIRSAMIRYTLDSICSSAFG 575
++D I++L+ +++ T + ICS FG
Sbjct: 140 RSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFG 185
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 33.5 bits (73), Expect = 0.92
Identities = 37/166 (22%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLV 452
++ + F+ R + FANG++WKV+R+ FS M++
Sbjct: 85 REALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRR-----FSVTTMRDFGMGK 139
Query: 453 EKCNHSLEDMLDKEIKDLQ-----IIEIRSAMIRYTLDSICSSAFG 575
++D I++L+ +++ T + ICS FG
Sbjct: 140 RSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFG 185
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 33.1 bits (72), Expect = 1.2
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPLF 416
P +VL +P+ I+ + T +DN K + + + + GDKW R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 417 SSLKMKNMFYLVEK-CNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
+K+ + K N L+ + +++ + TLDS+ F +S+
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSH 213
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 33.1 bits (72), Expect = 1.2
Identities = 46/205 (22%), Positives = 83/205 (40%), Gaps = 4/205 (1%)
Frame = +3
Query: 6 VSALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQK 185
V A A +L TY +Y + R+ + P + +F ++ +T V +
Sbjct: 25 VGASWLLARILAWTYAFYHNGRRL-----RCFPQPRKQNWFLGHLGLVTPTEEGLRVLTQ 79
Query: 186 LCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQVF-TKDFYYFNSRDNSDYNH-KEVVTQN 356
L +P F + G P + L +P+I++ V T D +D Y K +
Sbjct: 80 LVATYPQG--FVRWLGPITPIINLCHPDIVRSVINTSDA--ITDKDIVFYKTLKPWLGDG 135
Query: 357 LFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDK-EIKDLQIIEIRSAM 533
L + GDKW+ R+ LTP F +K + K + + + ++ +++ +
Sbjct: 136 LLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHI 195
Query: 534 IRYTLDSICSSAFGIESNTLREGGE 608
TLDS+ F +SN + E
Sbjct: 196 SLMTLDSLQKCIFSFDSNCQEKPSE 220
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 33.1 bits (72), Expect = 1.2
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPLF 416
P +VL +P+ I+ + T +DN K + + + + GDKW R+ LTP F
Sbjct: 31 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 89
Query: 417 SSLKMKNMFYLVEK-CNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
+K+ + K N L+ + +++ + TLDS+ F +S+
Sbjct: 90 HFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSH 147
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 32.7 bits (71), Expect = 1.6
Identities = 29/126 (23%), Positives = 51/126 (40%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ A + +T + S + + K P P+PF GNY++ T +I D K
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNT--EHICDSIMKF 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+ + P F G A+VL + +++ F+ R + F+
Sbjct: 62 SECY--GPVFTIHLGPRRAVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFS 119
Query: 369 NGDKWK 386
NG++ K
Sbjct: 120 NGERAK 125
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 32.7 bits (71), Expect = 1.6
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 278
P P+P GN ++ Y G +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R +FF+NG++W+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 32.7 bits (71), Expect = 1.6
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 278
P P+P GN ++ Y G +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R +FF+NG++W+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 32.7 bits (71), Expect = 1.6
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 278
P P+P GN ++ Y G +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R +FF+NG++W+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 32.7 bits (71), Expect = 1.6
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Frame = +3
Query: 102 PYAKPVPFFGNYMRYITLQSYIGDVTQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 278
P P+P GN ++ Y G +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 279 VFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
F+ R +FF+NG++W+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 32.3 bits (70), Expect = 2.1
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPLF 416
P +VL +P+ I+ + T +DN K + + + + GDKW R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 417 SSLKMKNMFYLVEK-CNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
+K+ + K N L+ + +++ + TLDS+ F +S+
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSH 213
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 32.3 bits (70), Expect = 2.1
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPLF 416
P +VL +P+ I+ + T +DN K + + + + GDKW R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 417 SSLKMKNMFYLVEK-CNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
+K+ + K N L+ + +++ + TLDS+ F +S+
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSH 213
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 32.3 bits (70), Expect = 2.1
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPLF 416
P +VL +P+ I+ + T +DN K + + + + GDKW R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 417 SSLKMKNMFYLVEK-CNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
+K+ + K N L+ + +++ + TLDS+ F +S+
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSH 213
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 32.3 bits (70), Expect = 2.1
Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPLF 416
P +VL +P+ I+ + T +DN K + + + + GDKW R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 417 SSLKMKNMFYLVEK-CNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIESN 587
+K+ + K N L+ + +++ + TLDS+ F +S+
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSH 213
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 31.5 bits (68), Expect = 3.7
Identities = 28/126 (22%), Positives = 50/126 (39%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ A + +T + S + + K P P+PF GNY++ T +I D K
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNT--EHICDSIMKF 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+ + P F G +VL + +++ F+ R + F+
Sbjct: 62 SECY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFEWVFKGYGVAFS 119
Query: 369 NGDKWK 386
NG++ K
Sbjct: 120 NGERAK 125
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 31.1 bits (67), Expect = 4.9
Identities = 28/126 (22%), Positives = 50/126 (39%)
Frame = +3
Query: 9 SALVFAAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSYIGDVTQKL 188
S L+ A + +T + S + + K P P+PF GNY++ T +I D K
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNT--EHICDSIMKF 61
Query: 189 CQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFA 368
+ + P F G +VL + +++ F+ R + F+
Sbjct: 62 SECY--GPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFS 119
Query: 369 NGDKWK 386
NG++ K
Sbjct: 120 NGERAK 125
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 31.1 bits (67), Expect = 4.9
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
++ F+ R + FANG++WKV+R+
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRR 126
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 31.1 bits (67), Expect = 4.9
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
++ F+ R + FANG++WKV+R+
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRR 126
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 31.1 bits (67), Expect = 4.9
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
++ F+ R + FANG++WKV+R+
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRR 126
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 31.1 bits (67), Expect = 4.9
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
++ F+ R + FANG++WKV+R+
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRR 126
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 31.1 bits (67), Expect = 4.9
Identities = 35/160 (21%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 180 QKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQ 353
Q+ + FP PY+ +G + + L +P+ +K + + +S+ + Y +
Sbjct: 76 QERVKTFPSACPYW--IWGGKVRVQLYDPDYMKVILGRS----DSKSHGSYKFLAPWIGY 129
Query: 354 NLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAM 533
+L NG W R+ LTP F +K L+ + D ++ + +E +
Sbjct: 130 SLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHV 189
Query: 534 IRYTLDSICSSAFGIESNTLREGGENS---PFANMGSIVF 644
TLD+I SAF + + + S +++ S+VF
Sbjct: 190 SLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLSSLVF 229
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 31.1 bits (67), Expect = 4.9
Identities = 34/160 (21%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 180 QKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQ 353
Q+ + FP PY+ +G + + L +P+ +K + + + + + Y +
Sbjct: 76 QERVKTFPSACPYW--IWGGKVRVQLYDPDYMKVILGRS----DPKSHGSYKFLAPRIGY 129
Query: 354 NLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAM 533
L NG W R+ LTP F + +K L+ + D ++ + +E+ +
Sbjct: 130 GLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHV 189
Query: 534 IRYTLDSICSSAFGIESNTLREGGENS---PFANMGSIVF 644
TLD+I SAF + + + S +++ S+VF
Sbjct: 190 SLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVF 229
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 31.1 bits (67), Expect = 4.9
Identities = 34/160 (21%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 180 QKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQ 353
Q+ + FP PY+ +G + + L +P+ +K + + + + + Y +
Sbjct: 76 QERVKTFPSACPYW--IWGGKVRVQLYDPDYMKVILGRS----DPKSHGSYKFLAPRIGY 129
Query: 354 NLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAM 533
L NG W R+ LTP F + +K L+ + D ++ + +E+ +
Sbjct: 130 GLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHV 189
Query: 534 IRYTLDSICSSAFGIESNTLREGGENS---PFANMGSIVF 644
TLD+I SAF + + + S +++ S+VF
Sbjct: 190 SLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVF 229
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 31.1 bits (67), Expect = 4.9
Identities = 34/160 (21%), Positives = 68/160 (42%), Gaps = 5/160 (3%)
Frame = +3
Query: 180 QKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQ 353
Q+ + FP PY+ +G + + L +P+ +K + + + + + Y +
Sbjct: 76 QERVKTFPSACPYW--IWGGKVRVQLYDPDYMKVILGRS----DPKSHGSYRFLAPRIGY 129
Query: 354 NLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAM 533
L NG W R+ LTP F + +K L+ + D ++ + +E+ +
Sbjct: 130 GLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHV 189
Query: 534 IRYTLDSICSSAFGIESNTLREGGENS---PFANMGSIVF 644
TLD+I SAF + + + S +++ S+VF
Sbjct: 190 SLMTLDTIMKSAFSHQGSIQVDRNSQSYIQAISDLNSLVF 229
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 31.1 bits (67), Expect = 4.9
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
++ F+ R + FANG++WKV+R+
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRR 126
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 31.1 bits (67), Expect = 4.9
Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +3
Query: 102 PYAKPVPFFGNYM---RYITLQSYIGDVTQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 272
P +P+P GN + R L+S++ + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 273 KQVFTKDFYYFNSRDNSDYNHKEVVTQNLFFANGDKWKVVRQ 398
++ F+ R + FANG++WKV+R+
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRR 126
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.9
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQNLFFANGDKWKVVRQNLTPLF 416
P L L +P+II+ V +D Y+ E + L + GDKW R+ LTP F
Sbjct: 97 PLLSLCHPDIIRSVINASAA-IAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAF 155
Query: 417 S-SLKMKNMFYLVEKCN--HSLEDMLDKE-IKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
++ M E N H+ +L E L + E S M TLDS+ F +S
Sbjct: 156 HFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLM---TLDSLQKCVFSFDS 212
Query: 585 NTLREGGE 608
+ + E
Sbjct: 213 HCQEKPSE 220
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 30.7 bits (66), Expect = 6.5
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 5/121 (4%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPL- 413
P LVL +P+ IK + +D+ Y K + L + GDKW R+ LTP
Sbjct: 105 PLLVLVHPDYIKPLLGASAA-IAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAF 163
Query: 414 -FSSLK--MKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
F LK MK + + + + L + E S M TLDS+ F S
Sbjct: 164 HFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLM---TLDSLQKCVFSYNS 220
Query: 585 N 587
N
Sbjct: 221 N 221
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 30.7 bits (66), Expect = 6.5
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 5/121 (4%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPL- 413
P LVL +P+ IK + +D+ Y K + L + GDKW R+ LTP
Sbjct: 105 PLLVLVHPDYIKPLLGASAA-IAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAF 163
Query: 414 -FSSLK--MKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
F LK MK + + + + L + E S M TLDS+ F S
Sbjct: 164 HFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLM---TLDSLQKCVFSYNS 220
Query: 585 N 587
N
Sbjct: 221 N 221
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 30.7 bits (66), Expect = 6.5
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 5/121 (4%)
Frame = +3
Query: 240 PALVLQNPEIIKQVFTKDFYYFNSRDNSDYNH-KEVVTQNLFFANGDKWKVVRQNLTPL- 413
P LVL +P+ IK + +D+ Y K + L + GDKW R+ LTP
Sbjct: 105 PLLVLVHPDYIKPLLGASAA-IAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAF 163
Query: 414 -FSSLK--MKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAMIRYTLDSICSSAFGIES 584
F LK MK + + + + L + E S M TLDS+ F S
Sbjct: 164 HFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLM---TLDSLQKCVFSYNS 220
Query: 585 N 587
N
Sbjct: 221 N 221
>BC043005-1|AAH43005.2| 794|Homo sapiens MGC39581 protein protein.
Length = 794
Score = 30.7 bits (66), Expect = 6.5
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Frame = +3
Query: 6 VSALVFAAF---VLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITL 155
VS LVFA F + TYIYY +T F +WK A+ + G + +L
Sbjct: 151 VSNLVFAYFRGDQISQTYIYYSNTGGFSFWKYHYDRQAEIIGSLGGIFHFFSL 203
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 30.3 bits (65), Expect = 8.6
Identities = 30/133 (22%), Positives = 57/133 (42%), Gaps = 2/133 (1%)
Frame = +3
Query: 180 QKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRDNSDYNHKEV-VTQ 353
Q+ + FP PY+ +G + + L +P+ +K + + + + + Y +
Sbjct: 76 QERVKTFPSACPYW--IWGGKVRVQLYDPDYMKVILGRS----DPKSHGSYKFLAPRIGY 129
Query: 354 NLFFANGDKWKVVRQNLTPLFSSLKMKNMFYLVEKCNHSLEDMLDKEIKDLQIIEIRSAM 533
L NG W R+ LTP F + +K L+ + D ++ + +E+ +
Sbjct: 130 GLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHV 189
Query: 534 IRYTLDSICSSAF 572
TLD+I SAF
Sbjct: 190 SLMTLDTIMKSAF 202
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,706,189
Number of Sequences: 237096
Number of extensions: 2469828
Number of successful extensions: 6425
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 6089
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6379
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9980595722
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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