BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= an--0316 (751 letters) Database: human 237,096 sequences; 76,859,062 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 151 3e-36 AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 151 3e-36 AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 151 3e-36 AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 151 3e-36 AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 89 1e-17 BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 87 5e-17 BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 87 5e-17 AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 87 5e-17 AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 87 5e-17 AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 87 5e-17 AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 87 5e-17 AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 87 5e-17 BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 83 8e-16 BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 83 8e-16 BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 83 8e-16 AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 83 8e-16 D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 83 1e-15 D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 83 1e-15 AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 83 1e-15 AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 83 1e-15 AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 83 1e-15 AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 83 1e-15 AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 81 3e-15 U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 81 6e-15 D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 81 6e-15 BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 81 6e-15 BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 81 6e-15 AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 81 6e-15 AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 81 6e-15 AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 81 6e-15 BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 80 7e-15 S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 77 9e-14 S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 77 9e-14 L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 77 9e-14 D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 77 9e-14 D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 77 9e-14 BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 77 9e-14 AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 77 9e-14 AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 77 9e-14 AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 77 9e-14 AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 77 9e-14 BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 76 2e-13 AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 76 2e-13 AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 76 2e-13 AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 76 2e-13 AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 76 2e-13 AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 76 2e-13 AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 75 2e-13 AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 75 2e-13 AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 75 4e-13 AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 75 4e-13 BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 74 5e-13 BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 72 2e-12 AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 72 3e-12 J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 71 3e-12 AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 71 4e-12 AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 71 6e-12 AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 71 6e-12 X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 70 8e-12 DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 70 8e-12 AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 70 8e-12 AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 70 8e-12 AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 70 8e-12 AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 70 8e-12 AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 70 8e-12 AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 70 8e-12 AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 70 1e-11 AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 70 1e-11 AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 70 1e-11 AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 70 1e-11 AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 70 1e-11 BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11 AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 69 2e-11 AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11 AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11 BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 69 2e-11 AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 68 4e-11 AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 57 8e-08 AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 57 8e-08 AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 57 8e-08 X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 40 0.013 M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 40 0.013 M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 40 0.013 DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 40 0.013 DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 40 0.013 BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 40 0.013 BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 40 0.013 AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 40 0.013 AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 40 0.013 AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 40 0.013 AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 40 0.013 J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 37 0.067 AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 37 0.067 D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 37 0.089 BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 37 0.089 AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 37 0.089 AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 37 0.089 AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.16 AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.16 AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.16 AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.16 AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 36 0.16 AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 36 0.16 AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 36 0.16 AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.16 AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 36 0.16 AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 36 0.16 J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 36 0.21 EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 36 0.21 EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 36 0.21 BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 36 0.21 AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 36 0.21 M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 35 0.36 D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 35 0.36 AY010111-1|AAG27034.2| 3354|Homo sapiens cadherin 23 protein. 33 0.83 AL772287-2|CAI13626.1| 3359|Homo sapiens cadherin-like 23 protein. 33 0.83 AL731541-6|CAI40841.1| 3359|Homo sapiens cadherin-like 23 protein. 33 0.83 AL359183-3|CAI13426.1| 3359|Homo sapiens cadherin-like 23 protein. 33 0.83 AF312024-1|AAG48303.1| 3354|Homo sapiens cadherin related 23 pro... 33 0.83 J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 31 3.3 DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 31 3.3 BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 31 3.3 AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 31 3.3 AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 31 4.4 U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 31 5.8 BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 31 5.8 AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 31 5.8 AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 31 5.8 AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 31 5.8 >BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4, subfamily V, polypeptide 2 protein. Length = 525 Score = 151 bits (366), Expect = 3e-36 Identities = 66/159 (41%), Positives = 104/159 (65%), Gaps = 2/159 (1%) Frame = +2 Query: 281 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 460 + F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 634 G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL 751 ++ C ++I+ ETAMG + Q EY AV +M +++ Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230 >AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 protein. Length = 525 Score = 151 bits (366), Expect = 3e-36 Identities = 66/159 (41%), Positives = 104/159 (65%), Gaps = 2/159 (1%) Frame = +2 Query: 281 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 460 + F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 634 G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL 751 ++ C ++I+ ETAMG + Q EY AV +M +++ Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230 >AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens cDNA FLJ44509 fis, clone UTERU3001585, weakly similar to Cytochrome P450 4c3 (EC 1.14.-.-). ). Length = 503 Score = 151 bits (366), Expect = 3e-36 Identities = 66/159 (41%), Positives = 104/159 (65%), Gaps = 2/159 (1%) Frame = +2 Query: 281 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 460 + F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL Sbjct: 50 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 109 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 634 G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y Sbjct: 110 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 169 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL 751 ++ C ++I+ ETAMG + Q EY AV +M +++ Sbjct: 170 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 208 >AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar to CYTOCHROME P450 4C1 (EC 1.14.14.1). ). Length = 525 Score = 151 bits (366), Expect = 3e-36 Identities = 66/159 (41%), Positives = 104/159 (65%), Gaps = 2/159 (1%) Frame = +2 Query: 281 DIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWL 460 + F+ I++ + +Y H ++K+W+GP +V LY+ +VEVIL+S IDK+ Y+F +PWL Sbjct: 72 EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN--FDCHDY 634 G GLL STG KWRS RK++ PTFH +L+ F+D+ N + +V KL+K + F+C Y Sbjct: 132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFY 191 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKMCDIL 751 ++ C ++I+ ETAMG + Q EY AV +M +++ Sbjct: 192 ITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230 >AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. Length = 458 Score = 89.4 bits (212), Expect = 1e-17 Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Frame = +2 Query: 290 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 460 +N Q SA Y IW+GP + + L P + I ++ I + RF KPWL Sbjct: 9 KNSTQMSATYSQGFT--IWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 66 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASN-FDCH 628 G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E S+ D Sbjct: 67 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMF 126 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 +++S T++ L + Q++ EY ++++ Sbjct: 127 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILEL 162 >BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 12 protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 49/157 (31%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Frame = +2 Query: 290 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 460 ++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASN-FDCH 628 G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E S+ D Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMF 192 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 +++S T++ L + Q++ EY ++++ Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILEL 228 >BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 45/141 (31%), Positives = 78/141 (55%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + I S+ + + Y F KPWLG+GLL+S G KW HR Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + DK ++ AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 + Q++ EY A++++ Sbjct: 209 SFESNCQEKPS-EYIAAILEL 228 >AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 49/157 (31%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Frame = +2 Query: 290 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 460 ++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 628 G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 +++S T++ L + Q++ EY ++++ Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILEL 228 >AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform 4F12 protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 49/157 (31%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Frame = +2 Query: 290 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 460 ++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 628 G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 +++S T++ L + Q++ EY ++++ Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILEL 228 >AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 45/141 (31%), Positives = 78/141 (55%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + I S+ + + Y F KPWLG+GLL+S G KW HR Sbjct: 89 KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + DK ++ AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 + Q++ EY A++++ Sbjct: 209 SFESNCQEKPS-EYIAAILEL 228 >AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 49/157 (31%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Frame = +2 Query: 290 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 460 ++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 628 G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 +++S T++ L + Q++ EY ++++ Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILEL 228 >AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. Length = 524 Score = 87.4 bits (207), Expect = 5e-17 Identities = 49/157 (31%), Positives = 83/157 (52%), Gaps = 7/157 (4%) Frame = +2 Query: 290 RNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEEY--RFFKPWL 460 ++ Q SA Y V W+GP + + L P + I ++ I + RF KPWL Sbjct: 75 KDSTQMSATYSQGFTV--WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWL 132 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKE-ASNFDCH 628 G G+L+S G KW HR+++ P FH N+LKS+I +FN ++ ++DK L E +S D Sbjct: 133 GEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMF 192 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 +++S T++ L + Q++ EY ++++ Sbjct: 193 EHISLMTLDSLQKCIFSFDSHCQERPS-EYIATILEL 228 >BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 protein. Length = 531 Score = 83.4 bits (197), Expect = 8e-16 Identities = 46/153 (30%), Positives = 86/153 (56%), Gaps = 7/153 (4%) Frame = +2 Query: 302 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 472 +K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144 Query: 473 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 640 L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204 Query: 641 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 T++ L + + + Q++ +Y A++++ Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236 >BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 protein. Length = 531 Score = 83.4 bits (197), Expect = 8e-16 Identities = 46/153 (30%), Positives = 86/153 (56%), Gaps = 7/153 (4%) Frame = +2 Query: 302 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 472 +K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144 Query: 473 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 640 L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204 Query: 641 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 T++ L + + + Q++ +Y A++++ Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236 >BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 22 protein. Length = 531 Score = 83.4 bits (197), Expect = 8e-16 Identities = 46/153 (30%), Positives = 86/153 (56%), Gaps = 7/153 (4%) Frame = +2 Query: 302 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 472 +K D H V+ +W+GP L L+ L P ++ +L + I ++ Y F KPWLG+GL Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGL 144 Query: 473 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 640 L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204 Query: 641 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 T++ L + + + Q++ +Y A++++ Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236 >AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. Length = 520 Score = 83.4 bits (197), Expect = 8e-16 Identities = 65/208 (31%), Positives = 104/208 (50%), Gaps = 9/208 (4%) Frame = +2 Query: 143 LVPAVILW-YAYWRMSRR-RLYELADKLNXXXXXXXXXNALEFVGGSADIFRNIVQKSAD 316 L+ ++ W YA++ RR R + K N L V + + R + Q A Sbjct: 30 LLARILAWTYAFYHNGRRLRCFPQPRKQNWFLGH------LGLVTPTEEGLRVLTQLVAT 83 Query: 317 YDHESVVKIWIGPRL-LVFLYDPRDVE-VILSSHVYIDK-AEEYRFFKPWLGNGLLISTG 487 Y + V+ W+GP ++ L P V VI +S DK Y+ KPWLG+GLL+S G Sbjct: 84 YP-QGFVR-WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVG 141 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANS---RAVVDKLKKEASN-FDCHDYMSECTVE 655 KWR HR+L+ P FH N+LK +I +F+ ++ A +L E S D +++S T++ Sbjct: 142 DKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHISLMTLD 201 Query: 656 ILLETAMGVSKSTQDQSGFEYAMAVMKM 739 L + + Q++ EY A+M++ Sbjct: 202 SLQKCIFSFDSNCQEKPS-EYITAIMEL 228 >D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV protein. Length = 389 Score = 83.0 bits (196), Expect = 1e-15 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 7/139 (5%) Frame = +2 Query: 344 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 514 W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++ Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 682 + P FH N+LK ++ +FN + + K L E S D +++S T++ L + Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210 Query: 683 SKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 211 DSHCQEKPS-EYIAAILEL 228 >D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV protein. Length = 520 Score = 83.0 bits (196), Expect = 1e-15 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 7/139 (5%) Frame = +2 Query: 344 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 514 W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++ Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 682 + P FH N+LK ++ +FN + + K L E S D +++S T++ L + Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210 Query: 683 SKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 211 DSHCQEKPS-EYIAAILEL 228 >AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 3 protein. Length = 520 Score = 83.0 bits (196), Expect = 1e-15 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 7/139 (5%) Frame = +2 Query: 344 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 514 W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++ Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 682 + P FH N+LK ++ +FN + + K L E S D +++S T++ L + Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210 Query: 683 SKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 211 DSHCQEKPS-EYIAAILEL 228 >AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 83.0 bits (196), Expect = 1e-15 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 7/139 (5%) Frame = +2 Query: 344 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 514 W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++ Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 682 + P FH N+LK ++ +FN + + K L E S D +++S T++ L + Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210 Query: 683 SKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 211 DSHCQEKPS-EYIAAILEL 228 >AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 83.0 bits (196), Expect = 1e-15 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 7/139 (5%) Frame = +2 Query: 344 WIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHRKL 514 W+GP +V ++ P ++ +L + I ++ Y F KPWLG+GLL+S G+KW HR++ Sbjct: 91 WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRM 150 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEAS-NFDCHDYMSECTVEILLETAMGV 682 + P FH N+LK ++ +FN + + K L E S D +++S T++ L + Sbjct: 151 LTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSF 210 Query: 683 SKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 211 DSHCQEKPS-EYIAAILEL 228 >AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. Length = 520 Score = 82.6 bits (195), Expect = 1e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGPRLLVFLY-DPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP V + P + ++++ I ++ Y F KPWLG+GLL+S G+KW HR Sbjct: 89 KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS----NFDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens cDNA FLJ39501 fis, clone PROST2016980, moderately similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ). Length = 531 Score = 81.4 bits (192), Expect = 3e-15 Identities = 45/153 (29%), Positives = 85/153 (55%), Gaps = 7/153 (4%) Frame = +2 Query: 302 QKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGL 472 +K D H V+ +W+GP L L+ L P ++ +L + ++ Y F KPWLG+GL Sbjct: 86 KKVLDNMHH-VLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGL 144 Query: 473 LISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKK----EASNFDCHDYMS 640 L+S G KW HR+L+ P FH ++LK ++ +FN ++ + K + A + D +++S Sbjct: 145 LLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHIS 204 Query: 641 ECTVEILLETAMGVSKSTQDQSGFEYAMAVMKM 739 T++ L + + + Q++ +Y A++++ Sbjct: 205 LMTLDSLQKCVFSYNSNCQEKMS-DYISAIIEL 236 >U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily IVF, polypeptide 2 protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hydroxylase protein. Length = 520 Score = 80.6 bits (190), Expect = 6e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 protein. Length = 520 Score = 80.2 bits (189), Expect = 7e-15 Identities = 42/141 (29%), Positives = 77/141 (54%), Gaps = 7/141 (4%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN----FDCHDYMSECTVEILLETAM 676 +++ P FH N+LK ++ +FN + + K + AS D +++S T++ L + Sbjct: 149 RMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMFEHISLMTLDSLQKCVF 208 Query: 677 GVSKSTQDQSGFEYAMAVMKM 739 Q++ EY A++++ Sbjct: 209 SFDSHCQEKPS-EYIAAILEL 228 >S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase protein. Length = 591 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase protein. Length = 519 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. Length = 519 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxylase protein. Length = 519 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase protein. Length = 521 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. Length = 455 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 11 protein. Length = 519 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 11 protein. Length = 455 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 11 protein. Length = 519 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily IVA, polypeptide 11 protein. Length = 519 Score = 76.6 bits (180), Expect = 9e-14 Identities = 43/141 (30%), Positives = 76/141 (53%), Gaps = 5/141 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAMGVSKS 691 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A S Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207 Query: 692 TQ-DQSGFEYAMAVMKMCDIL 751 Q D++ Y A+ + +++ Sbjct: 208 IQVDRNSQSYIQAISDLNNLV 228 >BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4, subfamily X, polypeptide 1 protein. Length = 509 Score = 75.8 bits (178), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223 >AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. Length = 509 Score = 75.8 bits (178), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223 >AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. Length = 509 Score = 75.8 bits (178), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223 >AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4, subfamily X, polypeptide 1 protein. Length = 509 Score = 75.8 bits (178), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223 >AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to CYTOCHROME P450 4A4 (EC 1.14.14.1). ). Length = 509 Score = 75.8 bits (178), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 83 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 139 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 140 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 199 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 200 ETNCQTNSTHDPYAKAIFELSKII 223 >AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to CYTOCHROME P450 4A4 (EC 1.14.14.1). ). Length = 444 Score = 75.8 bits (178), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 75 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 134 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 135 ETNCQTNSTHDPYAKAIFELSKII 158 >AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 protein. Length = 519 Score = 75.4 bits (177), Expect = 2e-13 Identities = 43/146 (29%), Positives = 76/146 (52%), Gaps = 5/146 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDSKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ-DQSGFEYAMAVMKMCDIL 751 S Q D++ Y A+ + ++ Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLSSLV 228 >AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar to CYTOCHROME P450 4A4 (EC 1.14.14.1). ). Length = 508 Score = 75.4 bits (177), Expect = 2e-13 Identities = 44/144 (30%), Positives = 78/144 (54%), Gaps = 8/144 (5%) Frame = +2 Query: 344 WIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEY--RFFKPWLGNGLLISTGQKWRSHRKL 514 WIGP F +YDP + +LS D +Y +F P LG GL G KW HR+L Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASNFD----CHDYMSECTVEILLETAMGV 682 + P FH N+LK++I++ + + ++DK +K S D +++++ +++I+++ A Sbjct: 139 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFSK 198 Query: 683 SKSTQDQSGFE-YAMAVMKMCDIL 751 + Q S + YA A+ ++ I+ Sbjct: 199 ETNCQTNSTHDPYAKAIFELSKII 222 >AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K protein. Length = 519 Score = 74.5 bits (175), Expect = 4e-13 Identities = 43/146 (29%), Positives = 77/146 (52%), Gaps = 5/146 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ-DQSGFEYAMAVMKMCDIL 751 S Q D++ Y A+ + +++ Sbjct: 203 SHQGSIQVDRNSQSYIQAISDLNNLV 228 >AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hydroxylase protein. Length = 175 Score = 74.5 bits (175), Expect = 4e-13 Identities = 31/80 (38%), Positives = 51/80 (63%), Gaps = 3/80 (3%) Frame = +2 Query: 338 KIWIGP-RLLVFLYDPRDVEVILSSHVYIDKAEE--YRFFKPWLGNGLLISTGQKWRSHR 508 K+W+GP L+ L P + ++++ I ++ Y F +PWLG+GLL+S G KW HR Sbjct: 89 KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLLSAGDKWSRHR 148 Query: 509 KLIAPTFHLNVLKSFIDLFN 568 +++ P FH N+LK ++ +FN Sbjct: 149 RMLTPAFHFNILKPYMKIFN 168 >BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. Length = 455 Score = 74.1 bits (174), Expect = 5e-13 Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 5/139 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F PW+G LL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ-DQSGFEYAMAV 730 S Q D++ Y A+ Sbjct: 203 SHQGSIQVDRNSQSYIQAI 221 >BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. Length = 215 Score = 72.1 bits (169), Expect = 2e-12 Identities = 38/114 (33%), Positives = 64/114 (56%), Gaps = 4/114 (3%) Frame = +2 Query: 344 WI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRKLIA 520 W+ G ++ V LYDP ++VIL YRF PW+G GLL+ GQ W HR+++ Sbjct: 89 WLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLT 147 Query: 521 PTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETA 673 P FH ++LK ++ L + R ++DK L + S + ++S T++ +++ A Sbjct: 148 PAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201 >AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydroxylase CYP4A11 protein. Length = 519 Score = 71.7 bits (168), Expect = 3e-12 Identities = 44/139 (31%), Positives = 73/139 (52%), Gaps = 5/139 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL YRF P +G GLL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPRIGYGLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ-DQSGFEYAMAV 730 S Q D++ Y A+ Sbjct: 203 SHQGSIQVDRNSQSYIQAI 221 >J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cytochrome P450 (IV subfamily) BI protein, complete cds. ). Length = 511 Score = 71.3 bits (167), Expect = 3e-12 Identities = 57/214 (26%), Positives = 99/214 (46%), Gaps = 7/214 (3%) Frame = +2 Query: 110 TFSAINLFYVLLVPAV-ILWYAYWRMSRRRLYELADKLNXXXXXXXXXNALEFVG-GSAD 283 +FS++ L+ L+ + L + + RR L + DK +ALE GS D Sbjct: 9 SFSSLGLWASGLILVLGFLKLIHLLLRRRTLAKAMDKFPGPPTHWLFGHALEIQETGSLD 68 Query: 284 IFRNIVQKSADYDHESVVKIWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPW 457 +V + + + +W G + + +Y+P + + S KA + Y FF W Sbjct: 69 ---KVVSWAHQFPYAH--PLWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQW 121 Query: 458 LGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCH 628 +G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD Sbjct: 122 IGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIF 181 Query: 629 DYMSECTVEILLETAMGVSKSTQDQSGFEYAMAV 730 + + L++ G + Y +AV Sbjct: 182 CDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAV 215 >AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to CYTOCHROME P450 4A1 (EC 1.14.15.3). ). Length = 340 Score = 70.9 bits (166), Expect = 4e-12 Identities = 38/143 (26%), Positives = 78/143 (54%), Gaps = 5/143 (3%) Frame = +2 Query: 335 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 511 V +W+GP + F ++DP V+++L A ++ + W+G GL+ G KW+ HR+ Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQDP-KSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138 Query: 512 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 682 ++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198 Query: 683 SKSTQ-DQSGFEYAMAVMKMCDI 748 S Q D + Y AV + I Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221 >AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22 protein. Length = 455 Score = 70.5 bits (165), Expect = 6e-12 Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 5/139 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ-DQSGFEYAMAV 730 S Q D++ Y A+ Sbjct: 203 SHQGSIQVDRNSQSYIQAI 221 >AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22 protein. Length = 519 Score = 70.5 bits (165), Expect = 6e-12 Identities = 43/139 (30%), Positives = 73/139 (52%), Gaps = 5/139 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ-DQSGFEYAMAV 730 S Q D++ Y A+ Sbjct: 203 SHQGSIQVDRNSQSYIQAI 221 >X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for cytochrome P-450HP. ). Length = 511 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 511 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. Length = 292 Score = 70.1 bits (164), Expect = 8e-12 Identities = 38/143 (26%), Positives = 76/143 (53%), Gaps = 5/143 (3%) Frame = +2 Query: 335 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 511 V +W+GP + F ++DP V+++L A ++ + W+G GL+ G KW+ HR+ Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138 Query: 512 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEA---SNFDCHDYMSECTVEILLETAMGV 682 ++ P F++++LK FI + + + R +++K ++ S + ++S T+ +++ A Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAHNSRLELFQHVSLMTLHSIMKCAFSH 198 Query: 683 SKSTQ-DQSGFEYAMAVMKMCDI 748 S Q D + Y AV + I Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221 >AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. Length = 511 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450 protein. Length = 295 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 511 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 511 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. Length = 511 Score = 70.1 bits (164), Expect = 8e-12 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. Length = 505 Score = 69.7 bits (163), Expect = 1e-11 Identities = 39/143 (27%), Positives = 76/143 (53%), Gaps = 5/143 (3%) Frame = +2 Query: 335 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 511 V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+ Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138 Query: 512 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 682 ++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198 Query: 683 SKSTQ-DQSGFEYAMAVMKMCDI 748 S Q D + Y AV + I Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221 >AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. Length = 505 Score = 69.7 bits (163), Expect = 1e-11 Identities = 39/143 (27%), Positives = 76/143 (53%), Gaps = 5/143 (3%) Frame = +2 Query: 335 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 511 V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+ Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138 Query: 512 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 682 ++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198 Query: 683 SKSTQ-DQSGFEYAMAVMKMCDI 748 S Q D + Y AV + I Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221 >AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. Length = 511 Score = 69.7 bits (163), Expect = 1e-11 Identities = 40/135 (29%), Positives = 68/135 (50%), Gaps = 5/135 (3%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGVS 685 + P FH +VLK ++ +F ++R ++DK ++ E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKCTFGRG 200 Query: 686 KSTQDQSGFEYAMAV 730 + Y +AV Sbjct: 201 DTGLGHRDSSYYLAV 215 >AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4, subfamily Z, polypeptide 1 protein. Length = 505 Score = 69.7 bits (163), Expect = 1e-11 Identities = 39/143 (27%), Positives = 76/143 (53%), Gaps = 5/143 (3%) Frame = +2 Query: 335 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 511 V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+ Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138 Query: 512 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 682 ++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198 Query: 683 SKSTQ-DQSGFEYAMAVMKMCDI 748 S Q D + Y AV + I Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221 >AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4, subfamily Z, polypeptide 1 protein. Length = 505 Score = 69.7 bits (163), Expect = 1e-11 Identities = 39/143 (27%), Positives = 76/143 (53%), Gaps = 5/143 (3%) Frame = +2 Query: 335 VKIWIGPRLLVF-LYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSHRK 511 V +W+GP + F ++DP D IL A ++ + W+G GL+ G KW+ HR+ Sbjct: 80 VPLWVGPFTMFFSVHDP-DYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138 Query: 512 LIAPTFHLNVLKSFIDLFNANSRAVVDKLKK---EASNFDCHDYMSECTVEILLETAMGV 682 ++ P F++++LK FI + + + R +++K ++ + S + ++S T++ +++ A Sbjct: 139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198 Query: 683 SKSTQ-DQSGFEYAMAVMKMCDI 748 S Q D + Y AV + I Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKI 221 >BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 512 Score = 68.9 bits (161), Expect = 2e-11 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 679 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198 >AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450 4B1 protein. Length = 512 Score = 68.9 bits (161), Expect = 2e-11 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 679 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198 >AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 512 Score = 68.9 bits (161), Expect = 2e-11 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 679 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198 >AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 512 Score = 68.9 bits (161), Expect = 2e-11 Identities = 37/118 (31%), Positives = 63/118 (53%), Gaps = 5/118 (4%) Frame = +2 Query: 341 IWIGPRL-LVFLYDPRDVEVILSSHVYIDKAEE-YRFFKPWLGNGLLISTGQKWRSHRKL 514 +W G + + +Y+P + + S KA + Y FF W+G GLL+ G KW HRKL Sbjct: 83 LWFGQFIGFLNIYEPDYAKAVYSRGD--PKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKL 140 Query: 515 IAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHDYMSECTVEILLETAMG 679 + P FH +VLK ++ +F ++R ++DK + +E +FD + + L++ G Sbjct: 141 LTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG 198 >BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. Length = 357 Score = 68.5 bits (160), Expect = 2e-11 Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ 697 S Q Sbjct: 203 SHQGSIQ 209 >AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family 4, subfamily A, polypeptide 22 protein. Length = 421 Score = 67.7 bits (158), Expect = 4e-11 Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 4/127 (3%) Frame = +2 Query: 329 SVVKIWI-GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKPWLGNGLLISTGQKWRSH 505 S WI G ++ V LYDP ++VIL Y+F P +G GLL+ GQ W H Sbjct: 84 SACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQTWFQH 142 Query: 506 RKLIAPTFHLNVLKSFIDLFNANSRAVVDK---LKKEASNFDCHDYMSECTVEILLETAM 676 R+++ P FH ++LK ++ L + R ++DK L + S + ++S T++ ++++A Sbjct: 143 RRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAF 202 Query: 677 GVSKSTQ 697 S Q Sbjct: 203 SHQGSIQ 209 >AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450 4B1 variant protein. Length = 497 Score = 56.8 bits (131), Expect = 8e-08 Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%) Frame = +2 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHD 631 G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167 Query: 632 YMSECTVEILLETAMG 679 + + L++ G Sbjct: 168 DVGHMALNTLMKCTFG 183 >AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 497 Score = 56.8 bits (131), Expect = 8e-08 Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%) Frame = +2 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHD 631 G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167 Query: 632 YMSECTVEILLETAMG 679 + + L++ G Sbjct: 168 DVGHMALNTLMKCTFG 183 >AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4, subfamily B, polypeptide 1 protein. Length = 497 Score = 56.8 bits (131), Expect = 8e-08 Identities = 26/76 (34%), Positives = 43/76 (56%), Gaps = 3/76 (3%) Frame = +2 Query: 461 GNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLK---KEASNFDCHD 631 G GLL+ G KW HRKL+ P FH +VLK ++ +F ++R ++DK + +E +FD Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167 Query: 632 YMSECTVEILLETAMG 679 + + L++ G Sbjct: 168 DVGHMALNTLMKCTFG 183 >X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for cytochrome P-450 (cyp3 locus). ). Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA encoding nifedipine oxidase, complete cds. ). Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome P-450 nifedipine oxidase mRNA, complet cds. ). Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3 subfamily A polypeptide 4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily IIIA, polypeptide 4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypeptide 4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 protein. Length = 503 Score = 39.5 bits (88), Expect = 0.013 Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTG 487 H+ K+W G + ++ + DP ++ +L Y R F P ++ + + I+ Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAED 123 Query: 488 QKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEI 658 ++W+ R L++PTF LK + + +V L++EA D ++++ Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDV 183 Query: 659 LLETAMGVS 685 + T+ GV+ Sbjct: 184 ITSTSFGVN 192 >J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine oxidase protein. Length = 502 Score = 37.1 bits (82), Expect = 0.067 Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 5/117 (4%) Frame = +2 Query: 350 GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 523 G + ++ + DP ++ +L Y R F P ++ + + I+ ++W+ R L++P Sbjct: 77 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 135 Query: 524 TFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 TF LK + + +V L++EA D +++++ T+ GV+ Sbjct: 136 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 192 >AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. Length = 430 Score = 37.1 bits (82), Expect = 0.067 Identities = 25/117 (21%), Positives = 54/117 (46%), Gaps = 5/117 (4%) Frame = +2 Query: 350 GPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAP 523 G + ++ + DP ++ +L Y R F P ++ + + I+ ++W+ R L++P Sbjct: 4 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 62 Query: 524 TFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 TF LK + + +V L++EA D +++++ T+ GV+ Sbjct: 63 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 119 >D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa protein. Length = 503 Score = 36.7 bits (81), Expect = 0.089 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Frame = +2 Query: 362 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 535 ++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139 Query: 536 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 LK + + +V L++EA +++++ T+ GVS Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192 >BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 7 protein. Length = 503 Score = 36.7 bits (81), Expect = 0.089 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Frame = +2 Query: 362 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 535 ++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139 Query: 536 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 LK + + +V L++EA +++++ T+ GVS Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192 >AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant 3A7 protein. Length = 535 Score = 36.7 bits (81), Expect = 0.089 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Frame = +2 Query: 362 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 535 ++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139 Query: 536 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 LK + + +V L++EA +++++ T+ GVS Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192 >AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypeptide 7 protein. Length = 503 Score = 36.7 bits (81), Expect = 0.089 Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Frame = +2 Query: 362 LVFLYDPRDVEVILSSHVYIDKAEEYRFFKP--WLGNGLLISTGQKWRSHRKLIAPTFHL 535 ++ + DP ++ +L Y R F P ++ N + I+ ++W+ R L++PTF Sbjct: 81 MLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTS 139 Query: 536 NVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 LK + + +V L++EA +++++ T+ GVS Sbjct: 140 GKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVS 192 >AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1 protein. Length = 503 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3 protein. Length = 503 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 503 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43 protein. Length = 503 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 250 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 420 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 504 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily IIIA polypeptide 43 protein. Length = 503 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. Length = 504 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. Length = 503 Score = 35.9 bits (79), Expect = 0.16 Identities = 23/119 (19%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 341 IWIGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQKWRSHRKLI 517 ++ G + ++ + DP ++ +L Y + +L + L + ++W+ R L+ Sbjct: 74 LYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLL 133 Query: 518 APTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEILLETAMGVS 685 +P F K + + + +V L++EA N + D+ T++++ T GV+ Sbjct: 134 SPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVN 192 >J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. Length = 491 Score = 35.5 bits (78), Expect = 0.21 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = +2 Query: 275 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 448 S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105 Query: 449 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 613 GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151 >EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 variant protein. Length = 321 Score = 35.5 bits (78), Expect = 0.21 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = +2 Query: 275 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 448 S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105 Query: 449 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 613 GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151 >EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 variant protein. Length = 491 Score = 35.5 bits (78), Expect = 0.21 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = +2 Query: 275 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 448 S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105 Query: 449 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 613 GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151 >BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. Length = 320 Score = 35.5 bits (78), Expect = 0.21 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = +2 Query: 275 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 448 S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105 Query: 449 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 613 GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151 >AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 protein. Length = 495 Score = 35.5 bits (78), Expect = 0.21 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = +2 Query: 275 SADIFRNIVQKSADYDHESVVKIWIGPRLLVFLYDPRDVEVIL--SSHVYIDKAEEYRFF 448 S D+ ++ + S +Y S+ + +GPR +V L + V+ L + + + FF Sbjct: 48 SQDMLTSLTKLSKEYG--SMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFF 105 Query: 449 KPWLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEAS 613 GNG+ S+G +W+ R+ F + +L++ F R++ +++ +E S Sbjct: 106 NFTKGNGIAFSSGDRWKVLRQ-----FSIQILRN----FGMGKRSIEERILEEGS 151 >M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glucocorticoid-inducible cytochrome P-450 (HLp) mRNA, complete cds. ). Length = 504 Score = 34.7 bits (76), Expect = 0.36 Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 490 H+ K+W G + ++ + DP ++++L Y F ++ + + I+ + Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124 Query: 491 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 661 +W+ R L++PTF LK + + +V L++E D +++++ Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184 Query: 662 LETAMGVS 685 ++ GV+ Sbjct: 185 TSSSFGVN 192 >D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. Length = 504 Score = 34.7 bits (76), Expect = 0.36 Identities = 24/128 (18%), Positives = 57/128 (44%), Gaps = 7/128 (5%) Frame = +2 Query: 323 HESVVKIW---IGPRLLVFLYDPRDVEVILSSHVYIDKAEEYRFFKP-WLGNGLLISTGQ 490 H+ K+W G + ++ + DP ++++L Y F ++ + + I+ + Sbjct: 65 HKKYGKVWGFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVGFMKSAISIAEDE 124 Query: 491 KWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDCHDYMSECTVEIL 661 +W+ R L++PTF LK + + +V L++E D +++++ Sbjct: 125 EWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVI 184 Query: 662 LETAMGVS 685 ++ GV+ Sbjct: 185 TSSSFGVN 192 >AY010111-1|AAG27034.2| 3354|Homo sapiens cadherin 23 protein. Length = 3354 Score = 33.5 bits (73), Expect = 0.83 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Frame = -1 Query: 502 RPPFLTSTDKKTVSEPWFEETVF--LSFIDVNVTTQDDFHVARIVQKDEETRSYPDLNDG 329 RP FL +V E TV ++ ID ++ + ++H+ IV KD+ R P+ D Sbjct: 2171 RPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDA 2230 Query: 328 FVIVVSAFLNYVSEDVSR 275 F + ++ V ++R Sbjct: 2231 FAVNINTGSVMVKSPMNR 2248 >AL772287-2|CAI13626.1| 3359|Homo sapiens cadherin-like 23 protein. Length = 3359 Score = 33.5 bits (73), Expect = 0.83 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Frame = -1 Query: 502 RPPFLTSTDKKTVSEPWFEETVF--LSFIDVNVTTQDDFHVARIVQKDEETRSYPDLNDG 329 RP FL +V E TV ++ ID ++ + ++H+ IV KD+ R P+ D Sbjct: 2176 RPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDA 2235 Query: 328 FVIVVSAFLNYVSEDVSR 275 F + ++ V ++R Sbjct: 2236 FAVNINTGSVMVKSPMNR 2253 >AL731541-6|CAI40841.1| 3359|Homo sapiens cadherin-like 23 protein. Length = 3359 Score = 33.5 bits (73), Expect = 0.83 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Frame = -1 Query: 502 RPPFLTSTDKKTVSEPWFEETVF--LSFIDVNVTTQDDFHVARIVQKDEETRSYPDLNDG 329 RP FL +V E TV ++ ID ++ + ++H+ IV KD+ R P+ D Sbjct: 2176 RPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDA 2235 Query: 328 FVIVVSAFLNYVSEDVSR 275 F + ++ V ++R Sbjct: 2236 FAVNINTGSVMVKSPMNR 2253 >AL359183-3|CAI13426.1| 3359|Homo sapiens cadherin-like 23 protein. Length = 3359 Score = 33.5 bits (73), Expect = 0.83 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Frame = -1 Query: 502 RPPFLTSTDKKTVSEPWFEETVF--LSFIDVNVTTQDDFHVARIVQKDEETRSYPDLNDG 329 RP FL +V E TV ++ ID ++ + ++H+ IV KD+ R P+ D Sbjct: 2176 RPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDA 2235 Query: 328 FVIVVSAFLNYVSEDVSR 275 F + ++ V ++R Sbjct: 2236 FAVNINTGSVMVKSPMNR 2253 >AF312024-1|AAG48303.1| 3354|Homo sapiens cadherin related 23 protein. Length = 3354 Score = 33.5 bits (73), Expect = 0.83 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Frame = -1 Query: 502 RPPFLTSTDKKTVSEPWFEETVF--LSFIDVNVTTQDDFHVARIVQKDEETRSYPDLNDG 329 RP FL +V E TV ++ ID ++ + ++H+ IV KD+ R P+ D Sbjct: 2171 RPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDA 2230 Query: 328 FVIVVSAFLNYVSEDVSR 275 F + ++ V ++R Sbjct: 2231 FAVNINTGSVMVKSPMNR 2248 >J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 protein. Length = 502 Score = 31.5 bits (68), Expect = 3.3 Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = +2 Query: 455 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 625 ++ + + ++ ++W+ R L++PTF LK + +V L++EA Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172 Query: 626 HDYMSECTVEILLETAMGVS 685 D +++++ T+ GV+ Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192 >DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450, family 3, subfamily A, polypeptide 5 protein. Length = 347 Score = 31.5 bits (68), Expect = 3.3 Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = +2 Query: 455 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 625 ++ + + ++ ++W+ R L++PTF LK + +V L++EA Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172 Query: 626 HDYMSECTVEILLETAMGVS 685 D +++++ T+ GV+ Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192 >BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 5 protein. Length = 502 Score = 31.5 bits (68), Expect = 3.3 Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = +2 Query: 455 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 625 ++ + + ++ ++W+ R L++PTF LK + +V L++EA Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172 Query: 626 HDYMSECTVEILLETAMGVS 685 D +++++ T+ GV+ Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192 >AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. Length = 502 Score = 31.5 bits (68), Expect = 3.3 Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = +2 Query: 455 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 625 ++ + + ++ ++W+ R L++PTF LK + +V L++EA Sbjct: 113 FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172 Query: 626 HDYMSECTVEILLETAMGVS 685 D +++++ T+ GV+ Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192 >AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 5 variant protein. Length = 502 Score = 31.1 bits (67), Expect = 4.4 Identities = 16/80 (20%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = +2 Query: 455 WLGNGLLISTGQKWRSHRKLIAPTFHLNVLKSFIDLFNANSRAVVDKLKKEASN---FDC 625 ++ + + ++ ++W+ R L++PTF LK + +V L++EA Sbjct: 113 FMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTL 172 Query: 626 HDYMSECTVEILLETAMGVS 685 D +++++ T+ GV+ Sbjct: 173 KDIFGAYSMDVITGTSFGVN 192 >U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxygenase CYP2J2 protein. Length = 502 Score = 30.7 bits (66), Expect = 5.8 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 464 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVDKLKKE-ASNFDCHDY 634 NGL++S+GQ W+ R+ L KS + ++ + + +K+E FD H Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 733 ++ I+ G QD S F+ + ++ Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215 >BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2, subfamily J, polypeptide 2 protein. Length = 502 Score = 30.7 bits (66), Expect = 5.8 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 464 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVDKLKKE-ASNFDCHDY 634 NGL++S+GQ W+ R+ L KS + ++ + + +K+E FD H Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 733 ++ I+ G QD S F+ + ++ Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215 >AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2, subfamily J, polypeptide 2 protein. Length = 502 Score = 30.7 bits (66), Expect = 5.8 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 464 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVDKLKKE-ASNFDCHDY 634 NGL++S+GQ W+ R+ L KS + ++ + + +K+E FD H Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 733 ++ I+ G QD S F+ + ++ Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215 >AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. Length = 502 Score = 30.7 bits (66), Expect = 5.8 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 464 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVDKLKKE-ASNFDCHDY 634 NGL++S+GQ W+ R+ L KS + ++ + + +K+E FD H Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 733 ++ I+ G QD S F+ + ++ Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215 >AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 protein. Length = 502 Score = 30.7 bits (66), Expect = 5.8 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 3/93 (3%) Frame = +2 Query: 464 NGLLISTGQKWRSHRKLIAPTFHLNVL--KSFIDLFNANSRAVVDKLKKE-ASNFDCHDY 634 NGL++S+GQ W+ R+ L KS + ++ + + +K+E FD H Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFK 183 Query: 635 MSECTVEILLETAMGVSKSTQDQSGFEYAMAVM 733 ++ I+ G QD S F+ + ++ Sbjct: 184 INNAVSNIICSITFGERFEYQD-SWFQQLLKLL 215 Database: human Posted date: Oct 23, 2007 1:18 PM Number of letters in database: 76,859,062 Number of sequences in database: 237,096 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 105,005,751 Number of Sequences: 237096 Number of extensions: 2194300 Number of successful extensions: 5432 Number of sequences better than 10.0: 129 Number of HSP's better than 10.0 without gapping: 5100 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5408 length of database: 76,859,062 effective HSP length: 88 effective length of database: 55,994,614 effective search space used: 9015132854 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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