Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0291
(698 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P00439 Cluster: Phenylalanine-4-hydroxylase; n=30; Euka... 260 2e-68
UniRef50_UPI000058423F Cluster: PREDICTED: hypothetical protein;... 233 3e-60
UniRef50_Q8IWU9 Cluster: Tryptophan 5-hydroxylase 2; n=135; Meta... 232 7e-60
UniRef50_P18459 Cluster: Tyrosine 3-monooxygenase; n=15; Endopte... 228 9e-59
UniRef50_P07101 Cluster: Tyrosine 3-monooxygenase; n=28; Deutero... 224 2e-57
UniRef50_P24529 Cluster: Tyrosine 3-monooxygenase; n=61; Coeloma... 223 2e-57
UniRef50_Q5DGG4 Cluster: SJCHGC01235 protein; n=2; Schistosoma|R... 215 9e-55
UniRef50_Q0PWM2 Cluster: Tyrosine hydroxylase isoform D2,8,9; n=... 213 3e-54
UniRef50_Q9W0K2 Cluster: CG9122-PA; n=4; Endopterygota|Rep: CG91... 208 1e-52
UniRef50_A6P4D3 Cluster: Tyrosine hydroxylase; n=1; Dugesia japo... 203 4e-51
UniRef50_P90986 Cluster: Tyrosine 3-monooxygenase; n=3; Caenorha... 201 2e-50
UniRef50_Q6WRI4 Cluster: Aromatic amino acid hydroxylase-like; n... 183 4e-45
UniRef50_A1Y9J6 Cluster: Tryptophan hydroxylase; n=1; Ciona inte... 182 1e-44
UniRef50_Q4SDY9 Cluster: Chromosome 13 SCAF14627, whole genome s... 176 4e-43
UniRef50_Q5S6Z8 Cluster: Henna; n=1; Bicyclus anynana|Rep: Henna... 175 1e-42
UniRef50_Q9XZD1 Cluster: Tryptophan hydroxylase; n=3; Caenorhabd... 171 1e-41
UniRef50_Q5ZNC6 Cluster: Tyrosine 3-monooxygenase; n=1; Ciona in... 161 1e-38
UniRef50_Q23A76 Cluster: Biopterin-dependent aromatic amino acid... 154 2e-36
UniRef50_O17446 Cluster: Tyrosine 3-monooxygenase; n=1; Schistos... 144 2e-33
UniRef50_A0C973 Cluster: Chromosome undetermined scaffold_16, wh... 142 6e-33
UniRef50_Q3W6S6 Cluster: Tyrosine 3-monooxygenase; n=3; Actinomy... 107 2e-22
UniRef50_Q124D5 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 103 4e-21
UniRef50_Q5ZS72 Cluster: Phenylalanine-4-hydroxylase; n=4; Legio... 101 1e-20
UniRef50_Q1RGM5 Cluster: Phenylalanine-4-hydroxylase; n=1; Ricke... 101 1e-20
UniRef50_A5P8R6 Cluster: Phenylalanine-4-hydroxylase; n=4; Sphin... 101 2e-20
UniRef50_Q0C2D1 Cluster: Phenylalanine-4-hydroxylase; n=1; Hypho... 99 5e-20
UniRef50_Q0ANJ2 Cluster: Phenylalanine-4-hydroxylase; n=2; Alpha... 96 6e-19
UniRef50_A3UHY3 Cluster: Phenylalanine-4-hydroxylase; n=1; Ocean... 95 1e-18
UniRef50_Q0LGC2 Cluster: Aromatic amino acid hydroxylase; n=3; C... 95 1e-18
UniRef50_A6FEK6 Cluster: Phenylalanine-4-hydroxylase; n=1; Morit... 95 2e-18
UniRef50_P43334 Cluster: Phenylalanine-4-hydroxylase; n=66; Gamm... 94 3e-18
UniRef50_Q2S0V6 Cluster: Tryptophan 5-hydroxylase 1; n=1; Salini... 94 3e-18
UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan... 93 6e-18
UniRef50_Q8XU39 Cluster: Phenylalanine-4-hydroxylase; n=40; Prot... 93 6e-18
UniRef50_Q98D72 Cluster: Phenylalanine-4-hydroxylase; n=1; Mesor... 92 1e-17
UniRef50_A7CCY2 Cluster: Phenylalanine-4-hydroxylase; n=8; Prote... 91 2e-17
UniRef50_A3HZI9 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 89 1e-16
UniRef50_Q1GTB6 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 88 2e-16
UniRef50_Q1VW50 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 88 2e-16
UniRef50_Q1ISS1 Cluster: Phenylalanine 4-monooxygenase; n=1; Aci... 87 3e-16
UniRef50_Q9KLB8 Cluster: Phenylalanine-4-hydroxylase; n=19; Vibr... 87 3e-16
UniRef50_Q2K9E9 Cluster: Phenylalanine-4-hydroxylase protein; n=... 85 2e-15
UniRef50_Q81LM9 Cluster: Phenylalanine-4-hydroxylase, putative; ... 83 6e-15
UniRef50_A4A633 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-14
UniRef50_Q9AG78 Cluster: Amino acid hydroxylase; n=1; Streptomyc... 77 6e-13
UniRef50_Q01Z53 Cluster: Aromatic amino acid hydroxylase; n=1; S... 76 7e-13
UniRef50_Q41AV6 Cluster: Aromatic amino acid hydroxylase; n=1; E... 72 1e-11
UniRef50_A6CNR8 Cluster: Phenylalanine 4-monooxygenase; n=1; Bac... 69 8e-11
UniRef50_Q11QP8 Cluster: Phenylalanine-4-hydroxylase; n=1; Cytop... 59 1e-07
UniRef50_A6E752 Cluster: Phenylalanine-4-hydroxylase; n=1; Pedob... 58 3e-07
UniRef50_A3U7E2 Cluster: Phenylalanine 4-monooxygenase; n=13; Ba... 56 6e-07
UniRef50_Q6MHK4 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_A7HE07 Cluster: Aromatic amino acid hydroxylase; n=5; C... 55 1e-06
UniRef50_Q255G4 Cluster: Aromatic amino acid hyroxylase biopteri... 55 2e-06
UniRef50_Q9Z6L3 Cluster: Probable aromatic amino acid hydroxylas... 54 3e-06
UniRef50_A4BFA1 Cluster: Probable aldose 1-epimerase; n=1; Reine... 36 1.3
UniRef50_A1RK23 Cluster: CRISPR-associated helicase Cas3 family;... 35 1.7
UniRef50_A1WTT4 Cluster: Putative Chase2 sensor protein precurso... 35 2.2
UniRef50_Q81WA2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.7
UniRef50_Q4QIF4 Cluster: Putative uncharacterized protein; n=3; ... 33 6.7
UniRef50_A4VDS2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.7
UniRef50_Q4RV58 Cluster: Chromosome 15 SCAF14992, whole genome s... 33 8.9
UniRef50_P88933 Cluster: ORF 45; n=3; Human herpesvirus 8|Rep: O... 33 8.9
UniRef50_Q982K5 Cluster: Transposase; n=9; Alphaproteobacteria|R... 33 8.9
UniRef50_A3LQA7 Cluster: Putative uncharacterized protein; n=3; ... 33 8.9
>UniRef50_P00439 Cluster: Phenylalanine-4-hydroxylase; n=30;
Eukaryota|Rep: Phenylalanine-4-hydroxylase - Homo
sapiens (Human)
Length = 452
Score = 260 bits (638), Expect = 2e-68
Identities = 113/178 (63%), Positives = 146/178 (82%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+P+YTPEPD+CHELLGH PLF+D +FAQFSQEIGLASLGAPD+YIEKLAT +WFTVEFGL
Sbjct: 274 KPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGL 333
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C+Q +KAYGAGLLSSFGELQYCLS+KP+L + E T Y +TE+QP+Y+VA SF
Sbjct: 334 CKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFN 393
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
DA+EK+ FA TIPR F VRY+PYTQ I++LD+ +Q+++L ++ E+ +L +A+ K+
Sbjct: 394 DAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKI 451
>UniRef50_UPI000058423F Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 522
Score = 233 bits (570), Expect = 3e-60
Identities = 104/177 (58%), Positives = 135/177 (76%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P++TPEPD CHELLGH P+ ADP FAQFSQEIGLASLG D+ I +LAT +WFTVEFGLC
Sbjct: 345 PMHTPEPDCCHELLGHVPMLADPTFAQFSQEIGLASLGVADEDITRLATLYWFTVEFGLC 404
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
RQ G+ +A GAGLLS+FGELQY LSDKPE R F+P T +Y YQP+YFVA+SF D
Sbjct: 405 RQNGETRACGAGLLSAFGELQYALSDKPEHRPFEPNKTAIQEYQDKNYQPIYFVADSFSD 464
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
AQ K+ +A + R + VRY+PYTQSI ++D ++R +R+++ +M +L +A++KL
Sbjct: 465 AQSKLRLYAMKMARPYNVRYDPYTQSIQVIDKVDKLRDAIRDLNGQMVVLTSAIEKL 521
>UniRef50_Q8IWU9 Cluster: Tryptophan 5-hydroxylase 2; n=135;
Metazoa|Rep: Tryptophan 5-hydroxylase 2 - Homo sapiens
(Human)
Length = 490
Score = 232 bits (567), Expect = 7e-60
Identities = 105/177 (59%), Positives = 140/177 (79%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
PLYTPEPD CHELLGH PL ADP FAQFSQEIGLASLGA D+ ++KLATC++FT+EFGLC
Sbjct: 308 PLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLC 367
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+QEGQL+AYGAGLLSS GEL++ LSDK ++ FDP++T + IT +Q YFV+ SFE+
Sbjct: 368 KQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEE 427
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A+EKM FA++I R F V +NPYTQSI+IL R I +++++ ++ + +A++K+
Sbjct: 428 AKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484
>UniRef50_P18459 Cluster: Tyrosine 3-monooxygenase; n=15;
Endopterygota|Rep: Tyrosine 3-monooxygenase - Drosophila
melanogaster (Fruit fly)
Length = 579
Score = 228 bits (558), Expect = 9e-59
Identities = 104/179 (58%), Positives = 137/179 (76%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P +TPEPD HELLGH PL ADP+FAQFSQEIGLASLGA D+ IEKL+T +WFTVEFGLC
Sbjct: 399 PYHTPEPDSIHELLGHMPLLADPSFAQFSQEIGLASLGASDEEIEKLSTVYWFTVEFGLC 458
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
++ GQ+KAYGAGLLSS+GEL + +SDK E R F+P ST Y EYQP+Y+VA SFED
Sbjct: 459 KEHGQIKAYGAGLLSSYGELLHAISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFED 518
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL*R 542
A++K ++ T+ R F VR+NP+T+ +++LDS ++ L+ +++ E+ L NA+ KL R
Sbjct: 519 AKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLVHQMNTEILHLTNAISKLRR 577
>UniRef50_P07101 Cluster: Tyrosine 3-monooxygenase; n=28;
Deuterostomia|Rep: Tyrosine 3-monooxygenase - Homo
sapiens (Human)
Length = 528
Score = 224 bits (547), Expect = 2e-57
Identities = 99/177 (55%), Positives = 133/177 (75%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T WFTVEFGLC
Sbjct: 351 PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLC 410
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q G++KAYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF D
Sbjct: 411 KQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSD 470
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A++K+ +A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 471 AKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 527
>UniRef50_P24529 Cluster: Tyrosine 3-monooxygenase; n=61;
Coelomata|Rep: Tyrosine 3-monooxygenase - Mus musculus
(Mouse)
Length = 498
Score = 223 bits (546), Expect = 2e-57
Identities = 100/177 (56%), Positives = 131/177 (74%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T +WFTVEFGLC
Sbjct: 321 PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLC 380
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q G+LKAYGAGLLSS+GEL + LS++PE+R FDP++ Y YQPVYFV+ SF D
Sbjct: 381 KQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFSD 440
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A++K+ +A I R F V+++PYT +ID+LDS IR + V E+ L A+ +
Sbjct: 441 AKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRRSLEGVQDELHTLTQALSAI 497
>UniRef50_Q5DGG4 Cluster: SJCHGC01235 protein; n=2; Schistosoma|Rep:
SJCHGC01235 protein - Schistosoma japonicum (Blood
fluke)
Length = 497
Score = 215 bits (525), Expect = 9e-55
Identities = 100/177 (56%), Positives = 129/177 (72%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD CHELLGH P+ ADP FA+FSQEIGLASLG DD I+KL+TC++FT+EFGLC
Sbjct: 297 PFYTPEPDCCHELLGHVPMLADPKFARFSQEIGLASLGTSDDEIKKLSTCYFFTIEFGLC 356
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
RQE QL+AYGAGLLSS ELQY LSDK ++ F P + +T +Q YF +SFED
Sbjct: 357 RQENQLRAYGAGLLSSVAELQYALSDKAVIKPFIPMEVINEECLVTTFQNGYFETSSFED 416
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A KM +F +TI R F VRYNPYTQSI+I++S + L++++ E+ + ++ K+
Sbjct: 417 ATHKMREFVRTIRRPFDVRYNPYTQSIEIIESPGSVANLIQDLQFELTTINESLLKM 473
>UniRef50_Q0PWM2 Cluster: Tyrosine hydroxylase isoform D2,8,9; n=31;
Eutheria|Rep: Tyrosine hydroxylase isoform D2,8,9 - Homo
sapiens (Human)
Length = 407
Score = 213 bits (521), Expect = 3e-54
Identities = 95/170 (55%), Positives = 127/170 (74%)
Frame = +3
Query: 27 DVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQEGQLK 206
D CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T +WFTVEFGLC+Q G++K
Sbjct: 237 DCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVK 296
Query: 207 AYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKMIK 386
AYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF DA++K+
Sbjct: 297 AYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRS 356
Query: 387 FAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
+A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 357 YASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 406
>UniRef50_Q9W0K2 Cluster: CG9122-PA; n=4; Endopterygota|Rep:
CG9122-PA - Drosophila melanogaster (Fruit fly)
Length = 555
Score = 208 bits (508), Expect = 1e-52
Identities = 96/178 (53%), Positives = 134/178 (75%), Gaps = 1/178 (0%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD CHELLGH PL A+ +FAQFSQEIGLASLGA D IEKLAT ++FTVEFGLC
Sbjct: 331 PFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIEKLATLYFFTVEFGLC 390
Query: 186 RQ-EGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
+Q + K YGAGLLSS ELQ+ ++ + ++++FDPE T + IT YQ Y+ +SFE
Sbjct: 391 KQADSTFKVYGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECIITSYQNAYYYTDSFE 450
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
+A+E+M FA++I R FGVRYNPYT S+++L +A++I ++ E+ ++ ++ +A+ K+
Sbjct: 451 EAKEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCSALRKI 508
>UniRef50_A6P4D3 Cluster: Tyrosine hydroxylase; n=1; Dugesia
japonica|Rep: Tyrosine hydroxylase - Dugesia japonica
(Planarian)
Length = 488
Score = 203 bits (495), Expect = 4e-51
Identities = 90/178 (50%), Positives = 131/178 (73%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+PL+TPEPD HELLGH P+ +D FA+FSQEIGL SLGA D IE+LAT +WFT+EFGL
Sbjct: 308 KPLHTPEPDCIHELLGHVPMLSDAEFAEFSQEIGLCSLGASDSDIERLATLYWFTIEFGL 367
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C + ++KA+GAGLLSSFGEL++ +S+ PE R FDP+ T Y +YQPVY+V +S
Sbjct: 368 CYENKKIKAFGAGLLSSFGELKHAISNIPEHRNFDPQVASVTPYKDEDYQPVYYVIDSVT 427
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
D +EK+ +FA++I R +RY+PYT++I+IL++ + + L R + E++ + N++ +
Sbjct: 428 DMKEKVRQFAKSIKRQNPIRYDPYTETIEILNNKKSVCHLGRVIKHELDTMENSLSSM 485
>UniRef50_P90986 Cluster: Tyrosine 3-monooxygenase; n=3;
Caenorhabditis|Rep: Tyrosine 3-monooxygenase -
Caenorhabditis elegans
Length = 454
Score = 201 bits (490), Expect = 2e-50
Identities = 87/177 (49%), Positives = 128/177 (72%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P ++PEPD+ HELLGH P+F+DP AQ SQ+IGL SLGA D++IEKL+T +WF VEFGLC
Sbjct: 272 PHHSPEPDLIHELLGHVPMFSDPLLAQMSQDIGLMSLGASDEHIEKLSTVYWFIVEFGLC 331
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+++G+LKA GAGLLS++GEL + SD PE ++FDP T KY +YQP+YFVA+S D
Sbjct: 332 KEDGKLKAIGAGLLSAYGELMHACSDAPEHKDFDPAVTAVQKYEDDDYQPLYFVADSIHD 391
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A K+ K+A ++ R F V Y+P+T+SI+ ++S+ + + ++ + +A D++
Sbjct: 392 ALAKLRKYASSMDRPFSVVYDPFTKSIEAIESSADLEKAFSRLSNDLSAITHAADRM 448
>UniRef50_Q6WRI4 Cluster: Aromatic amino acid hydroxylase-like; n=3;
Leishmania|Rep: Aromatic amino acid hydroxylase-like -
Leishmania major
Length = 453
Score = 183 bits (445), Expect = 4e-45
Identities = 80/148 (54%), Positives = 108/148 (72%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+PLYTPEPD+ H+++GH PL +DP FA F+Q IGLASLGA D+ ++KLA +W++VEFGL
Sbjct: 284 QPLYTPEPDMVHDIIGHLPLLSDPDFANFTQTIGLASLGASDELLDKLAKVYWYSVEFGL 343
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C + G+ KAYGAG+LSS GEL+Y LSDKPE +DP T +PIT+YQP+YFVA SF
Sbjct: 344 CSEGGRRKAYGAGILSSCGELEYALSDKPECVPWDPTMASKTPFPITKYQPLYFVAESFS 403
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSI 446
DAQ K+ + + + YN Y++ +
Sbjct: 404 DAQRKLEAWLSSQEKPLYTVYNSYSRRV 431
>UniRef50_A1Y9J6 Cluster: Tryptophan hydroxylase; n=1; Ciona
intestinalis|Rep: Tryptophan hydroxylase - Ciona
intestinalis (Transparent sea squirt)
Length = 448
Score = 182 bits (442), Expect = 1e-44
Identities = 82/185 (44%), Positives = 122/185 (65%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD+CHE+LGH PL ADP FAQFSQEIGLASLG D KLA C+ +TVEFGLC
Sbjct: 264 PYYTPEPDICHEILGHVPLLADPEFAQFSQEIGLASLGVSDQDTSKLAGCYLYTVEFGLC 323
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+++ +KAYGAGLLSS EL++ LS ++R FD + + +T +QPVYF++ SF
Sbjct: 324 KEQDGIKAYGAGLLSSISELKHALSSPEKVRAFDAVTASCQESHVTAFQPVYFLSPSFSQ 383
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL*RC 545
A+ +M FA T+ R F + ++ T S+ + D I+ + ++ ++ ++ A+ ++ +
Sbjct: 384 AKHEMRAFAATLERPFVLSFDEETSSVKVFDKLSSIQSAVSKMSHDLVVISKALGEMEKR 443
Query: 546 RLASC 560
++ C
Sbjct: 444 KIEVC 448
>UniRef50_Q4SDY9 Cluster: Chromosome 13 SCAF14627, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF14627, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 488
Score = 176 bits (429), Expect = 4e-43
Identities = 93/204 (45%), Positives = 130/204 (63%), Gaps = 27/204 (13%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHA----------------------PL-----FADPAFAQFSQEIG 104
P+++PEPD HELLGH PL FA+ + Q +G
Sbjct: 285 PMHSPEPDCVHELLGHVPMLANSTFAQFSQVRGRQRTFCPLRLSYVFANSPWIHPLQSLG 344
Query: 105 LASLGAPDDYIEKLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREF 284
LASLGA D+ IEKL+T +WFTVE+GLC+Q G++KAYGAGLLSS+GEL + LSD+PE+REF
Sbjct: 345 LASLGASDEDIEKLSTLYWFTVEYGLCKQNGEVKAYGAGLLSSYGELVHSLSDEPEVREF 404
Query: 285 DPESTGGTKYPITEYQPVYFVANSFEDAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSA 464
DP++ Y YQPVYF++ SF DA+EK ++ I R F VR++PYT SI++LD+
Sbjct: 405 DPDAAAVQPYQDQTYQPVYFISESFADAKEKFRRYVAGIKRPFSVRFDPYTTSIEVLDNP 464
Query: 465 RQIRVLMREVHQEMELLLNAMDKL 536
+I+ + V E+++L +A+ L
Sbjct: 465 LKIQGGLEGVKDELKMLADALSVL 488
>UniRef50_Q5S6Z8 Cluster: Henna; n=1; Bicyclus anynana|Rep: Henna -
Bicyclus anynana (squinting bush brown)
Length = 125
Score = 175 bits (425), Expect = 1e-42
Identities = 81/102 (79%), Positives = 90/102 (88%)
Frame = +3
Query: 201 LKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKM 380
LKA+GAGLLSSFGELQYCLSDKPELRE +P TG KYPITEYQPVYFVA SFE A+EKM
Sbjct: 1 LKAFGAGLLSSFGELQYCLSDKPELRESEPSVTGEQKYPITEYQPVYFVAQSFESAKEKM 60
Query: 381 IKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEM 506
IKFAQTIPR+FGVRYNPYTQSIDILDS RQ+ L++++ EM
Sbjct: 61 IKFAQTIPREFGVRYNPYTQSIDILDSPRQMTDLLKQIRTEM 102
>UniRef50_Q9XZD1 Cluster: Tryptophan hydroxylase; n=3;
Caenorhabditis|Rep: Tryptophan hydroxylase -
Caenorhabditis elegans
Length = 532
Score = 171 bits (417), Expect = 1e-41
Identities = 84/187 (44%), Positives = 119/187 (63%), Gaps = 13/187 (6%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD HEL+GH LFADP FAQFSQEIGLASLGA ++ ++KLAT ++F++EFGL
Sbjct: 342 PFYTPEPDTVHELMGHMALFADPDFAQFSQEIGLASLGASEEDLKKLATLYFFSIEFGLS 401
Query: 186 RQEG-------------QLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITE 326
+ + K YGAGLLSS GELQ+ + + FDP+ + IT
Sbjct: 402 SDDAADSPVKENGSNHERFKVYGAGLLSSAGELQHAVEGSATIIRFDPDRVVEQECLITT 461
Query: 327 YQPVYFVANSFEDAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEM 506
+Q YF +FE+AQ+K+ F + R F VRYNPYT+S+++L+++R I + + + ++
Sbjct: 462 FQSAYFYTRNFEEAQQKLRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDI 521
Query: 507 ELLLNAM 527
LL A+
Sbjct: 522 NLLAGAL 528
>UniRef50_Q5ZNC6 Cluster: Tyrosine 3-monooxygenase; n=1; Ciona
intestinalis|Rep: Tyrosine 3-monooxygenase - Ciona
intestinalis (Transparent sea squirt)
Length = 429
Score = 161 bits (392), Expect = 1e-38
Identities = 75/142 (52%), Positives = 97/142 (68%), Gaps = 1/142 (0%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHEL+GH P+ DP FA +SQ+IGLASLG D I KLA +WFTVEFGLC
Sbjct: 274 PMHSPEPDCCHELIGHIPMLLDPTFALYSQQIGLASLGVSDSDITKLAALYWFTVEFGLC 333
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
++ LKAYGAGL+SS+GELQ+ LSD P E T Y + YQP+YFV+ SF++
Sbjct: 334 KENNVLKAYGAGLMSSYGELQHALSDVPMHLPLQAERTCLQPYEDSVYQPIYFVSESFDE 393
Query: 366 AQEKMIKFAQ-TIPRDFGVRYN 428
A ++ F+Q R F + YN
Sbjct: 394 AFNQVRAFSQHCTKRGFDITYN 415
>UniRef50_Q23A76 Cluster: Biopterin-dependent aromatic amino acid
hydroxylase family protein; n=2; Tetrahymena thermophila
SB210|Rep: Biopterin-dependent aromatic amino acid
hydroxylase family protein - Tetrahymena thermophila
SB210
Length = 448
Score = 154 bits (374), Expect = 2e-36
Identities = 64/146 (43%), Positives = 96/146 (65%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
YTPEPD+ HE++GH P+FADP A SQEIGL S+GA D+ + +L +WFT+EFG C++
Sbjct: 291 YTPEPDIVHEVVGHIPMFADPVVADISQEIGLLSIGANDEQLRRLGNIYWFTLEFGACKE 350
Query: 192 EGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQ 371
G++KAYGAG++ GE ++ LS + DP +YPI + QPVY NSFE+
Sbjct: 351 NGKMKAYGAGIIGCIGECEHFLSQNSRFKYLDPFKDCDREYPIQKVQPVYCYTNSFEECL 410
Query: 372 EKMIKFAQTIPRDFGVRYNPYTQSID 449
E+++KF + + + Y+ T++I+
Sbjct: 411 ERLVKFGEQMKKPMKTWYDFNTETIE 436
>UniRef50_O17446 Cluster: Tyrosine 3-monooxygenase; n=1; Schistosoma
mansoni|Rep: Tyrosine 3-monooxygenase - Schistosoma
mansoni (Blood fluke)
Length = 465
Score = 144 bits (349), Expect = 2e-33
Identities = 69/176 (39%), Positives = 105/176 (59%), Gaps = 3/176 (1%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
RP++TPEPD HEL+GH P+ + FA FSQE+GLASLGA ++ I +L+T +WFTVEFGL
Sbjct: 283 RPMHTPEPDCIHELIGHMPMLVNRQFADFSQELGLASLGASEEEITRLSTLYWFTVEFGL 342
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C + G+ +A GAG++SS+GEL+ SD F+ Y YQ +YFV S E
Sbjct: 343 CNENGETRALGAGIMSSYGELENAFSDLSVKEPFNINDAAVQVYDDVGYQKIYFVTESIE 402
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQE---MELLLN 521
+ ++ + T + Y+P T+++ + + L++ V +E ++ LLN
Sbjct: 403 SMKRELRNYINTSGKSTIPIYDPITETVHMKSRFSIRKELLKHVKEEIGQLDTLLN 458
>UniRef50_A0C973 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 431
Score = 142 bits (345), Expect = 6e-33
Identities = 66/148 (44%), Positives = 92/148 (62%), Gaps = 7/148 (4%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD+ HEL+GH PLFAD A SQEIG+ S G + +L T +WFT+EFG C
Sbjct: 265 PEYTPEPDIVHELVGHVPLFADKEVADLSQEIGILSCGTEQKDLSRLGTLYWFTLEFGAC 324
Query: 186 RQEGQLKAYGAGLLSSFGE-----LQYCLSDKPE--LREFDPESTGGTKYPITEYQPVYF 344
++ GQ+K +GAG+ SS GE +QY + P+ +FDP YPI QPVY
Sbjct: 325 KENGQIKGFGAGIASSIGECDVSNIQYLFQNFPKANYEKFDPFIHADRPYPIQTVQPVYM 384
Query: 345 VANSFEDAQEKMIKFAQTIPRDFGVRYN 428
SFE+A +++I F +++ + FG+ Y+
Sbjct: 385 YTESFEEAMQELIIFGKSLQKPFGLYYD 412
>UniRef50_Q3W6S6 Cluster: Tyrosine 3-monooxygenase; n=3;
Actinomycetales|Rep: Tyrosine 3-monooxygenase - Frankia
sp. EAN1pec
Length = 296
Score = 107 bits (258), Expect = 2e-22
Identities = 54/124 (43%), Positives = 75/124 (60%), Gaps = 1/124 (0%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGL 182
P YTPEPD+ HE++GHA A FA + G A+ A D ++ ++ FWFT+EFG
Sbjct: 152 PFYTPEPDIIHEVVGHANALASDRFAALYRAAGEAARRAESADTLQFISKVFWFTLEFGT 211
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
++G+LKAYGAG+LSS+GE+ S +R D G T Y IT YQPV + A+SF
Sbjct: 212 VYEDGELKAYGAGILSSYGEMAEFRS--VNVRPLDVAIMGTTDYDITRYQPVLYAADSFG 269
Query: 363 DAQE 374
++
Sbjct: 270 QVED 273
>UniRef50_Q124D5 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=8; Burkholderiales|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 292
Score = 103 bits (247), Expect = 4e-21
Identities = 55/119 (46%), Positives = 70/119 (58%), Gaps = 2/119 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y EPDV H+L GH PL +P FA Q G L A E+L+ +W+TVEFGL R
Sbjct: 137 YIVEPDVFHDLFGHVPLLFNPVFADHMQAYGAGGLKAHALGACEQLSRLYWYTVEFGLIR 196
Query: 189 QEGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
Q L+AYGAG+LSS GEL Y + S +P+ + T T+Y I YQ YFV +SF+
Sbjct: 197 QANGLRAYGAGILSSSGELAYAVQSPEPQRIALNLLRTMRTRYKIDSYQQTYFVIDSFQ 255
>UniRef50_Q5ZS72 Cluster: Phenylalanine-4-hydroxylase; n=4;
Legionella pneumophila|Rep: Phenylalanine-4-hydroxylase
- Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 281
Score = 101 bits (243), Expect = 1e-20
Identities = 51/119 (42%), Positives = 66/119 (55%), Gaps = 1/119 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
Y EPD+ HEL GH P+ D +A+F + L P+ L FWFTVEFGL +
Sbjct: 123 YVQEPDIFHELFGHCPMLTDRVYAEFVHDYACKVLTFPEQDWPLLQRMFWFTVEFGLIKT 182
Query: 192 EGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
L+AYG G+LSS E YC+ SD P FDP Y I + QPVYFV +S+++
Sbjct: 183 PKGLRAYGGGILSSISETVYCVESDIPVRILFDPVVAFRMPYRIDQLQPVYFVIDSYQN 241
>UniRef50_Q1RGM5 Cluster: Phenylalanine-4-hydroxylase; n=1;
Rickettsia bellii RML369-C|Rep:
Phenylalanine-4-hydroxylase - Rickettsia bellii (strain
RML369-C)
Length = 246
Score = 101 bits (243), Expect = 1e-20
Identities = 52/119 (43%), Positives = 69/119 (57%), Gaps = 2/119 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATC-FWFTVEFGLCR 188
Y EPD+ H++ GH PL +P FA F Q+ GL L A + + K A+ +WFTVEFGL +
Sbjct: 112 YLEEPDIFHDVFGHVPLLVNPVFADFMQQFGLKGLEAIEAGMLKFASALYWFTVEFGLIQ 171
Query: 189 QEGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
L+ YGAG++SS GE Y L S+ P EFD T+Y +Q YFV SF+
Sbjct: 172 SNNGLRIYGAGIISSKGESIYSLESEIPMRLEFDLNKVIKTEYETDSFQKTYFVIKSFQ 230
>UniRef50_A5P8R6 Cluster: Phenylalanine-4-hydroxylase; n=4;
Sphingomonadales|Rep: Phenylalanine-4-hydroxylase -
Erythrobacter sp. SD-21
Length = 313
Score = 101 bits (241), Expect = 2e-20
Identities = 55/141 (39%), Positives = 80/141 (56%), Gaps = 3/141 (2%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y EPDV H++ GH P+ DP +A + QE G A A + ++ L + +W+TVEFGL
Sbjct: 138 YIQEPDVFHDVFGHVPMLTDPVYADYMQEYGKAGWKAMRYNRLKALGSLYWYTVEFGLIE 197
Query: 189 QE-GQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
++ G ++AYGAG+LS E+ Y + ++ P + + T Y I++ QP YFV SFE
Sbjct: 198 EKPGDIRAYGAGILSGPTEVVYSVEAESPNRIMLNVDRVMRTDYVISDLQPTYFVIPSFE 257
Query: 363 DAQEKMIKFAQTIPRDFGVRY 425
D F QT+ RDF Y
Sbjct: 258 DL------FRQTVERDFDKLY 272
>UniRef50_Q0C2D1 Cluster: Phenylalanine-4-hydroxylase; n=1;
Hyphomonas neptunium ATCC 15444|Rep:
Phenylalanine-4-hydroxylase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 293
Score = 99 bits (238), Expect = 5e-20
Identities = 53/127 (41%), Positives = 69/127 (54%), Gaps = 2/127 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y EPD+ H++ GH P+ ADP FA F + G A + LA +W+TVEFGL +
Sbjct: 122 YLQEPDIFHDIFGHVPMLADPVFADFMEAYGKGGQRAMRLGQLHNLARLYWYTVEFGLIQ 181
Query: 189 QEGQLKAYGAGLLSSFGELQYCLSD-KPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+E L+ YGAG+LSS E + L D P FD + TKY I ++Q YFV SFE
Sbjct: 182 EEDGLRIYGAGILSSPHETVFALEDASPNRIGFDLQRLMRTKYIIDDFQQTYFVIPSFEA 241
Query: 366 AQEKMIK 386
E K
Sbjct: 242 LLETCYK 248
>UniRef50_Q0ANJ2 Cluster: Phenylalanine-4-hydroxylase; n=2;
Alphaproteobacteria|Rep: Phenylalanine-4-hydroxylase -
Maricaulis maris (strain MCS10)
Length = 293
Score = 96.3 bits (229), Expect = 6e-19
Identities = 55/154 (35%), Positives = 79/154 (51%), Gaps = 2/154 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y PEPD+ H++ GH PL P FA + Q G L + + D I+ +A +W+TVEFGL
Sbjct: 120 YLPEPDIFHDVFGHVPLLTQPVFADYMQAYGKGGLRSLEFDAIKHMARLYWYTVEFGLIN 179
Query: 189 QEGQLKAYGAGLLSSFGELQYCLSDK-PELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+ YGAG++SS E + L K P FD E T Y ++Q YFV +S+E+
Sbjct: 180 TPEGRRIYGAGIVSSRTESIFSLEGKSPNRLHFDLERIMQTDYRYDDFQQSYFVIDSYEE 239
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSAR 467
E +A P + P + D+LD+ R
Sbjct: 240 LME--ATYADFAPIYESLPGRPEYKPSDLLDTDR 271
>UniRef50_A3UHY3 Cluster: Phenylalanine-4-hydroxylase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep:
Phenylalanine-4-hydroxylase - Oceanicaulis alexandrii
HTCC2633
Length = 370
Score = 95.5 bits (227), Expect = 1e-18
Identities = 47/123 (38%), Positives = 70/123 (56%), Gaps = 2/123 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y EPD H++ GH P+ +P FA + Q G A + + ++ + +W+TVEFGL
Sbjct: 185 YLQEPDTFHDIFGHVPMLMNPFFADYIQAYGAGGRRAIEYNRLKNFGSVYWYTVEFGLIL 244
Query: 189 QEGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+EG+L+ YGAG+LSS E + L SD P + PE T Y I+++Q YFV +S +
Sbjct: 245 EEGELRVYGAGILSSPDETLFSLYSDSPHRIKMVPERVMRTDYVISDFQETYFVVDSIKA 304
Query: 366 AQE 374
E
Sbjct: 305 LYE 307
>UniRef50_Q0LGC2 Cluster: Aromatic amino acid hydroxylase; n=3;
Chloroflexi (class)|Rep: Aromatic amino acid hydroxylase
- Herpetosiphon aurantiacus ATCC 23779
Length = 247
Score = 95.1 bits (226), Expect = 1e-18
Identities = 50/129 (38%), Positives = 71/129 (55%), Gaps = 1/129 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEK-LATCFWFTVEFGLCR 188
+TP PD+ HE GH P F + FA +Q G L A D+ + +A +WF+ EFGL R
Sbjct: 108 FTPLPDLFHEYFGHLPAFTNREFADIAQLFGPLYLSAKDERQQLGIARIWWFSTEFGLLR 167
Query: 189 QEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDA 368
+ G+LK GAGLLSS GEL + L+ + EFD E T Y YF+ NS +
Sbjct: 168 ENGELKVLGAGLLSSPGELLHALNPETPRYEFDIERVADTASAPYGYHEHYFILNSLDHL 227
Query: 369 QEKMIKFAQ 395
+ + ++A+
Sbjct: 228 RSIVYEYAE 236
>UniRef50_A6FEK6 Cluster: Phenylalanine-4-hydroxylase; n=1;
Moritella sp. PE36|Rep: Phenylalanine-4-hydroxylase -
Moritella sp. PE36
Length = 272
Score = 94.7 bits (225), Expect = 2e-18
Identities = 52/122 (42%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
Y EPD+ HEL GH PL + A+A FSQ G L A LA +WFT+EFGL +
Sbjct: 120 YIQEPDIFHELFGHCPLLTNQAYADFSQHYGELGLKADKADRPMLARLYWFTIEFGLMQS 179
Query: 192 EGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDA 368
+ LK +G G+LSS E Y L SD P + T Y I E Q YFV N D
Sbjct: 180 QQGLKIFGGGILSSKQETCYSLDSDIPNRQPLQVIEAFRTHYRIDELQKNYFVINQLSDL 239
Query: 369 QE 374
Q+
Sbjct: 240 QQ 241
>UniRef50_P43334 Cluster: Phenylalanine-4-hydroxylase; n=66;
Gammaproteobacteria|Rep: Phenylalanine-4-hydroxylase -
Pseudomonas aeruginosa
Length = 262
Score = 94.3 bits (224), Expect = 3e-18
Identities = 47/112 (41%), Positives = 62/112 (55%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
Y EPD+ HE+ GH PL +P FA+F+ G L A + LA +W T+EFGL
Sbjct: 113 YLQEPDIFHEIFGHCPLLTNPWFAEFTHTYGKLGLKASKEERVFLARLYWMTIEFGLVET 172
Query: 192 EGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFV 347
+ + YG G+LSS E Y LSD+P + F+P T Y I QP+YFV
Sbjct: 173 DQGKRIYGGGILSSPKETVYSLSDEPLHQAFNPLEAMRTPYRIDILQPLYFV 224
>UniRef50_Q2S0V6 Cluster: Tryptophan 5-hydroxylase 1; n=1;
Salinibacter ruber DSM 13855|Rep: Tryptophan
5-hydroxylase 1 - Salinibacter ruber (strain DSM 13855)
Length = 278
Score = 93.9 bits (223), Expect = 3e-18
Identities = 47/118 (39%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
YTP PD H++ GH P+ P FA F Q G A+ A +L WFTVEFGL ++
Sbjct: 145 YTPAPDCFHDIFGHMPMLTQPEFADFYQLYGQAAQNAEGADRPRLERFHWFTVEFGLIQE 204
Query: 192 EGQLKAYGAGLLSSFGELQYCLSDKPELREFDPES-TGGTKYPITEYQPVYFVANSFE 362
+G+ + +GAG++SS E+ + LS++ L FDPE Y + Q FV +SFE
Sbjct: 205 QGEKRIFGAGIVSSNEEVTHALSEEVTLHPFDPEHIVEKDDYEVYNLQEELFVLDSFE 262
>UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan
hydroxylase D1; n=7; Danio rerio|Rep: PREDICTED: similar
to tryptophan hydroxylase D1 - Danio rerio
Length = 488
Score = 93.1 bits (221), Expect = 6e-18
Identities = 41/49 (83%), Positives = 44/49 (89%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLAT 152
PLYTPEPD CHELLGH PL A+P+FAQFSQEIGLASLGA DD I+KLAT
Sbjct: 400 PLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDDSIQKLAT 448
>UniRef50_Q8XU39 Cluster: Phenylalanine-4-hydroxylase; n=40;
Proteobacteria|Rep: Phenylalanine-4-hydroxylase -
Ralstonia solanacearum (Pseudomonas solanacearum)
Length = 313
Score = 93.1 bits (221), Expect = 6e-18
Identities = 50/119 (42%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y EPD H++ GH PL +P FA + Q G L A ++ LA +W+TVEFGL R
Sbjct: 146 YLQEPDGFHDIFGHVPLLINPVFADYMQAYGQGGLKAARLGALDMLARLYWYTVEFGLIR 205
Query: 189 QEGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
L+ YGAG++SS E Y L S P FD T+Y I +Q YFV +SFE
Sbjct: 206 TPAGLRIYGAGIVSSKSESVYALDSASPNRIGFDVHRIMRTRYRIDTFQKTYFVIDSFE 264
>UniRef50_Q98D72 Cluster: Phenylalanine-4-hydroxylase; n=1;
Mesorhizobium loti|Rep: Phenylalanine-4-hydroxylase -
Rhizobium loti (Mesorhizobium loti)
Length = 275
Score = 91.9 bits (218), Expect = 1e-17
Identities = 52/124 (41%), Positives = 73/124 (58%), Gaps = 7/124 (5%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIG-----LASLGAPDDYIEKLATCFWFTVEF 176
Y EPD+ H+ GH P+ + P FA F Q G + +LG D+ I +L +W+T E+
Sbjct: 127 YIVEPDMFHDFFGHVPVLSQPVFADFMQMYGKKAGDIIALGG-DEMITRL---YWYTAEY 182
Query: 177 GLCRQEGQ-LKAYGAGLLSSFGELQYCLSDKPELR-EFDPESTGGTKYPITEYQPVYFVA 350
GL ++ GQ LKA+GAGL+SSF ELQ+ + K FD E+ T Y I ++Q YFV
Sbjct: 183 GLVQEAGQPLKAFGAGLMSSFTELQFAVEGKDAHHVPFDLETVMRTGYEIDKFQRAYFVL 242
Query: 351 NSFE 362
SF+
Sbjct: 243 PSFD 246
>UniRef50_A7CCY2 Cluster: Phenylalanine-4-hydroxylase; n=8;
Proteobacteria|Rep: Phenylalanine-4-hydroxylase -
Ralstonia pickettii 12D
Length = 349
Score = 91.1 bits (216), Expect = 2e-17
Identities = 48/119 (40%), Positives = 63/119 (52%), Gaps = 2/119 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD-DYIEKLATCFWFTVEFGLCR 188
Y EPD H++ GH PL +P FA + + G L A ++ LA +W+TVEFGL R
Sbjct: 182 YLQEPDCFHDIFGHVPLLINPIFADYMEAYGKGGLKAARLGQLDMLARLYWYTVEFGLIR 241
Query: 189 QEGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
L+ YGAG++SS E Y L S P FD T+Y I +Q YF +SFE
Sbjct: 242 TPAGLRIYGAGIVSSKSESVYALDSASPNRIGFDVRRIMRTRYRIDTFQKTYFTIDSFE 300
>UniRef50_A3HZI9 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=2; Flexibacteraceae|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Algoriphagus sp. PR1
Length = 259
Score = 89.0 bits (211), Expect = 1e-16
Identities = 42/132 (31%), Positives = 75/132 (56%), Gaps = 2/132 (1%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEI-GLASLGAPDDY-IEKLATCFWFTVEFGLC 185
Y EPD+ H+ H P+ + + F +++ G+A + + I+ L+ +WFT+EFGL
Sbjct: 119 YLQEPDMFHDAFAHMPMLTNQPYVDFLEKLSGIALKHINNPWAIQLLSRIYWFTIEFGLI 178
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
++ G+LK YGAG+LSS GE ++ LS++P ++D +Y +Q YFV ++E
Sbjct: 179 KEGGELKIYGAGILSSAGETKFSLSNEPNHIDYDVRRILNQEYWKDRFQDKYFVIENYEQ 238
Query: 366 AQEKMIKFAQTI 401
E + + + +
Sbjct: 239 LYESLPEIEEVL 250
>UniRef50_Q1GTB6 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=2; Sphingomonadaceae|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 290
Score = 88.2 bits (209), Expect = 2e-16
Identities = 50/123 (40%), Positives = 69/123 (56%), Gaps = 6/123 (4%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPD----DYIEKLATCFWFTVEFG 179
Y+ EPD+ H++ GH P+ A+PAF F G A L A DY+ +L + +TVEFG
Sbjct: 121 YSEEPDMFHDIFGHVPMLANPAFGDFLVAYGEAGLRAESLGASDYLGRL---WLYTVEFG 177
Query: 180 LCRQEGQLKAYGAGLLSSFGELQYCLSDKPELRE--FDPESTGGTKYPITEYQPVYFVAN 353
L +EG+L+A+G GLLSS E + L+ PE R D E T+Y +Q YFV
Sbjct: 178 LVVEEGELRAFGGGLLSSLAETAFALT-APEPRRIWLDVERAMRTRYHFDAFQQTYFVVE 236
Query: 354 SFE 362
F+
Sbjct: 237 GFD 239
>UniRef50_Q1VW50 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=1; Psychroflexus torquis ATCC 700755|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Psychroflexus torquis ATCC 700755
Length = 242
Score = 87.8 bits (208), Expect = 2e-16
Identities = 43/120 (35%), Positives = 69/120 (57%), Gaps = 3/120 (2%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQE---IGLASLGAPDDYIEKLATCFWFTVEFGL 182
Y EPDV H++ GH PL +DP F++F E +G LG + I+ L +WFT+EFG+
Sbjct: 103 YLEEPDVFHDIFGHVPLLSDPVFSEFVCEFGKLGCQFLGDTEKLIQ-LQRLYWFTIEFGV 161
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
+++G +++YGAG+LSS GE K ++ ++ ++ Q Y+V +SFE
Sbjct: 162 IKEQGSIQSYGAGILSSSGETNQIHEQKANFIDYSIQAIIEKEFRTDIMQEDYYVISSFE 221
>UniRef50_Q1ISS1 Cluster: Phenylalanine 4-monooxygenase; n=1;
Acidobacteria bacterium Ellin345|Rep: Phenylalanine
4-monooxygenase - Acidobacteria bacterium (strain
Ellin345)
Length = 250
Score = 87.4 bits (207), Expect = 3e-16
Identities = 44/122 (36%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIG-LASLGAPDDYIEKLATCFWFTVEFGLCR 188
YTPEPD+ H++ GH P+ A FA + Q +A D E+L FW+TVEFGL R
Sbjct: 118 YTPEPDIFHDIFGHVPMHAHKVFADYLQAFAQIARQITNDADQERLGRLFWYTVEFGLIR 177
Query: 189 QEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDA 368
+ +K YG+G++SS E + ++ +F E T + E QP F +FE
Sbjct: 178 EGSDVKMYGSGVISSVKEGDNVVHRGCKIHDFSLEEVLDTHVKVDELQPTLFAIENFEQI 237
Query: 369 QE 374
E
Sbjct: 238 YE 239
>UniRef50_Q9KLB8 Cluster: Phenylalanine-4-hydroxylase; n=19;
Vibrionaceae|Rep: Phenylalanine-4-hydroxylase - Vibrio
cholerae
Length = 289
Score = 87.4 bits (207), Expect = 3e-16
Identities = 47/113 (41%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
Y EPD HE+ GH + P FA F+ G A LA +WFTVEFGL ++
Sbjct: 136 YLQEPDFFHEVYGHCAMLTHPDFAAFTHVYGQLGAKATPKERSYLARLYWFTVEFGLVQE 195
Query: 192 EGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPITEYQPVYFV 347
+GQ K YG G+LSS GE Y S P+ FD T Y I QP+Y+V
Sbjct: 196 QGQTKIYGGGILSSPGETLYASESTIPKREPFDIMQVLRTPYRIDIMQPIYYV 248
>UniRef50_Q2K9E9 Cluster: Phenylalanine-4-hydroxylase protein; n=2;
Rhizobium|Rep: Phenylalanine-4-hydroxylase protein -
Rhizobium etli (strain CFN 42 / ATCC 51251)
Length = 263
Score = 84.6 bits (200), Expect = 2e-15
Identities = 45/121 (37%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQ 191
Y EPD+ HE+ GH PL + ++A F + G ++ Y L FWFTVEFGL
Sbjct: 114 YIEEPDLFHEVFGHCPLLTNQSYANFVRHFGETAMRLGKGYSWHLFRIFWFTVEFGLINT 173
Query: 192 EGQLKAYGAGLLSSFGELQYCLSDKP-ELREFDPESTGGTKYPITEYQPVYFVANSFEDA 368
+ +GAG++SS E + E R FD S T Y I QP+Y+V +SF D
Sbjct: 174 PQGRRCFGAGIVSSPSEAKAATEGTACEFRPFDLLSVLRTPYRIDILQPIYYVIDSFADL 233
Query: 369 Q 371
+
Sbjct: 234 E 234
>UniRef50_Q81LM9 Cluster: Phenylalanine-4-hydroxylase, putative;
n=10; Bacillus cereus group|Rep:
Phenylalanine-4-hydroxylase, putative - Bacillus
anthracis
Length = 584
Score = 83.0 bits (196), Expect = 6e-15
Identities = 40/88 (45%), Positives = 55/88 (62%)
Frame = +3
Query: 138 EKLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYP 317
E+++ FW+TVE+GL K YGAGLLSS GE ++CL+D E F E+ T Y
Sbjct: 203 EQISRLFWWTVEYGLIGDIDNPKIYGAGLLSSVGESKHCLTDAVEKVPFSIEACTSTTYD 262
Query: 318 ITEYQPVYFVANSFEDAQEKMIKFAQTI 401
+T+ QP FV SFE+ E + KFA+T+
Sbjct: 263 VTKMQPQLFVCKSFEELTEALEKFAETM 290
Score = 44.0 bits (99), Expect = 0.004
Identities = 15/31 (48%), Positives = 21/31 (67%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIG 104
YTP PD+ HE GHAP+ DP +A++ + G
Sbjct: 116 YTPAPDIVHEAAGHAPILLDPTYAKYVKRFG 146
>UniRef50_A4A633 Cluster: Putative uncharacterized protein; n=1;
Congregibacter litoralis KT71|Rep: Putative
uncharacterized protein - Congregibacter litoralis KT71
Length = 596
Score = 58.0 bits (134), Expect(2) = 2e-14
Identities = 38/105 (36%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
Frame = +3
Query: 96 EIGLASLGAPDDYIEK---LATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDK 266
E LA+LG D + L W+TVE+GL + + +GAGLLSS GE Q CL D+
Sbjct: 195 EARLAALGDSDGEPSEAALLTRLHWWTVEYGLVGELEDYRLFGAGLLSSLGESQSCLDDE 254
Query: 267 PELREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKMIKFAQTI 401
+ + T Y IT QP FV S + + +FA T+
Sbjct: 255 RVKKLPLTVNAVETPYDITSTQPQLFVTKSCRHMSQVLEEFAATM 299
Score = 44.0 bits (99), Expect(2) = 2e-14
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +3
Query: 9 LYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGA 122
LYTP PD+ HE GHAP D +A+F Q G + A
Sbjct: 124 LYTPAPDILHESAGHAPFLVDVDYAEFLQRFGEVGMQA 161
>UniRef50_Q9AG78 Cluster: Amino acid hydroxylase; n=1; Streptomyces
verticillus|Rep: Amino acid hydroxylase - Streptomyces
verticillus
Length = 244
Score = 76.6 bits (180), Expect = 6e-13
Identities = 43/122 (35%), Positives = 57/122 (46%), Gaps = 3/122 (2%)
Frame = +3
Query: 24 PDVCHELLGHAPLFADPAFAQFSQE---IGLASLGAPDDYIEKLATCFWFTVEFGLCRQE 194
PD+ H+L GH P A A QE IG+ G P+D+ L W T+E GL R
Sbjct: 111 PDLFHDLFGHGPYLAHARTADLYQEFGRIGVRCAGRPEDFA-LLQGILWSTLETGLIRTP 169
Query: 195 GQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQE 374
G L+A G +LSS E++ CL + FDPE Y I Q YF E+ +
Sbjct: 170 GGLRALGGAILSSADEIRQCLDPACPVEPFDPEVVRFATYDILRLQSRYFAVEDLEEIES 229
Query: 375 KM 380
+
Sbjct: 230 AL 231
>UniRef50_Q01Z53 Cluster: Aromatic amino acid hydroxylase; n=1;
Solibacter usitatus Ellin6076|Rep: Aromatic amino acid
hydroxylase - Solibacter usitatus (strain Ellin6076)
Length = 306
Score = 76.2 bits (179), Expect = 7e-13
Identities = 48/134 (35%), Positives = 67/134 (50%), Gaps = 17/134 (12%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGA---------PDDYIEKLATC--- 155
Y PEPD+ H++ GH P+ + FA G ++ A P + +L +
Sbjct: 130 YLPEPDIFHDVAGHVPMHTERQFADTLVRFGDCAVTAARITAEVKDPAKRVRRLTSIMRA 189
Query: 156 ----FWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCL-SDKPELREFDPESTGGTKYPI 320
FWFTVEFGL R AYG+GLLSS+GEL++ + SD+ + E I
Sbjct: 190 MSRFFWFTVEFGLMRGTKGTVAYGSGLLSSYGELEHAIESDEVQRYPIQLEWVINQVAEI 249
Query: 321 TEYQPVYFVANSFE 362
YQP+ FV +SFE
Sbjct: 250 DHYQPILFVVDSFE 263
>UniRef50_Q41AV6 Cluster: Aromatic amino acid hydroxylase; n=1;
Exiguobacterium sibiricum 255-15|Rep: Aromatic amino
acid hydroxylase - Exiguobacterium sibiricum 255-15
Length = 548
Score = 72.1 bits (169), Expect = 1e-11
Identities = 36/87 (41%), Positives = 50/87 (57%)
Frame = +3
Query: 141 KLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPI 320
+++ FW+TVEFGL + YGAGLLSS GE ++CL+D F TK+ +
Sbjct: 203 EISRLFWWTVEFGLIGDLDNPQIYGAGLLSSVGESRHCLTDAVVKHPFSLAKALATKHDV 262
Query: 321 TEYQPVYFVANSFEDAQEKMIKFAQTI 401
T Q FV SFE +E + +FAQT+
Sbjct: 263 TSMQKELFVCESFEQLREALEEFAQTM 289
Score = 45.2 bits (102), Expect = 0.002
Identities = 16/32 (50%), Positives = 22/32 (68%)
Frame = +3
Query: 9 LYTPEPDVCHELLGHAPLFADPAFAQFSQEIG 104
LYTP PD+ HE GHAP+ +P +A+F + G
Sbjct: 114 LYTPAPDILHEAAGHAPILMNPTYAEFVRRFG 145
>UniRef50_A6CNR8 Cluster: Phenylalanine 4-monooxygenase; n=1;
Bacillus sp. SG-1|Rep: Phenylalanine 4-monooxygenase -
Bacillus sp. SG-1
Length = 642
Score = 69.3 bits (162), Expect = 8e-11
Identities = 36/88 (40%), Positives = 52/88 (59%)
Frame = +3
Query: 138 EKLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYP 317
E+++ FW+TVEFGL + + YGAGLLSS GE + CLSD+ + F E T Y
Sbjct: 268 EQISRLFWWTVEFGLIGKVEKPMVYGAGLLSSVGESKACLSDQVKKIPFSIEECIKTSYD 327
Query: 318 ITEYQPVYFVANSFEDAQEKMIKFAQTI 401
+T Q FV SFE+ E + +F+ ++
Sbjct: 328 VTTMQKQLFVCESFEELIEAVEEFSASM 355
Score = 42.7 bits (96), Expect = 0.008
Identities = 15/31 (48%), Positives = 22/31 (70%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIG 104
YTP PD+ HE GHAP+ D +++F ++IG
Sbjct: 181 YTPAPDILHEAAGHAPILFDSTYSEFVKKIG 211
>UniRef50_Q11QP8 Cluster: Phenylalanine-4-hydroxylase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep:
Phenylalanine-4-hydroxylase - Cytophaga hutchinsonii
(strain ATCC 33406 / NCIMB 9469)
Length = 246
Score = 58.8 bits (136), Expect = 1e-07
Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Frame = +3
Query: 21 EPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDD--YIEKLATCFWFTVEFGLCRQE 194
E D+ H++ GH L P + + +++G +L +D I L +W T+++GL
Sbjct: 113 EYDIFHDVFGHTSLLYIPTYCLYLEQLGELALTYINDPKAILYLKRVYWHTIQYGLIEAN 172
Query: 195 GQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQE 374
L+ YGA +++S E Y L+ + + T Y +Q YFV +S+E
Sbjct: 173 KSLRIYGAHMITSRNEASYALNAGVPKYDHNVSIIMDTPYVKNHFQEKYFVISSYEQLLA 232
Query: 375 KM 380
M
Sbjct: 233 SM 234
>UniRef50_A6E752 Cluster: Phenylalanine-4-hydroxylase; n=1;
Pedobacter sp. BAL39|Rep: Phenylalanine-4-hydroxylase -
Pedobacter sp. BAL39
Length = 594
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Frame = +3
Query: 111 SLGAPDDYIEKLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCL-SDKPELREFD 287
++G P + + L W+TVE+GL K YGAGLLSS GE C+ SD P+L
Sbjct: 203 NMGEPSE-MALLGRLHWWTVEYGLIGTLEDPKIYGAGLLSSIGESSSCMKSDVPKL---- 257
Query: 288 PESTGGTKYP--ITEYQPVYFVANSFEDAQEKMIKFAQTI 401
P + +P IT+ QP FV +F++ + + +FA T+
Sbjct: 258 PYTIDAINHPYDITKTQPQLFVTETFQNLIDVLEQFADTM 297
Score = 38.7 bits (86), Expect = 0.14
Identities = 17/37 (45%), Positives = 22/37 (59%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGA 122
YTP PD+ HE GHAP+ AD + + G S+GA
Sbjct: 124 YTPAPDIIHESAGHAPIIADADYNSYLSYFG--SIGA 158
>UniRef50_A3U7E2 Cluster: Phenylalanine 4-monooxygenase; n=13;
Bacteroidetes|Rep: Phenylalanine 4-monooxygenase -
Croceibacter atlanticus HTCC2559
Length = 586
Score = 56.4 bits (130), Expect = 6e-07
Identities = 32/89 (35%), Positives = 47/89 (52%)
Frame = +3
Query: 135 IEKLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKY 314
I + W+TVE+GL K YGAGLLSS GE + C++D + + ++ +
Sbjct: 209 ISLIRNLHWWTVEYGLVGTVEDPKIYGAGLLSSIGESKNCMTDAVKKIPYSIDA-AYQDF 267
Query: 315 PITEYQPVYFVANSFEDAQEKMIKFAQTI 401
IT+ QP FV F QE + +FA T+
Sbjct: 268 DITKQQPQLFVTPDFAYLQEVLEEFANTM 296
Score = 41.9 bits (94), Expect = 0.015
Identities = 15/31 (48%), Positives = 21/31 (67%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQFSQEIG 104
YTP PD+ HE GHAP+ A P +A++ + G
Sbjct: 123 YTPAPDIIHEGAGHAPIIASPDYAEYLRRFG 153
>UniRef50_Q6MHK4 Cluster: Putative uncharacterized protein; n=1;
Bdellovibrio bacteriovorus|Rep: Putative uncharacterized
protein - Bdellovibrio bacteriovorus
Length = 580
Score = 56.0 bits (129), Expect = 8e-07
Identities = 31/74 (41%), Positives = 42/74 (56%)
Frame = +3
Query: 141 KLATCFWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPI 320
+L+ W+T E+GL + K +GAGLLSS GE ++CLS K + + T Y I
Sbjct: 203 ELSRMNWWTAEYGLIGELDNPKIFGAGLLSSVGESKWCLSQKVKKIPLTVDCI-KTSYDI 261
Query: 321 TEYQPVYFVANSFE 362
TE QP FVA F+
Sbjct: 262 TEPQPQLFVAKDFK 275
Score = 40.3 bits (90), Expect = 0.044
Identities = 14/30 (46%), Positives = 20/30 (66%)
Frame = +3
Query: 9 LYTPEPDVCHELLGHAPLFADPAFAQFSQE 98
LYTP PD+ HE GHAP+ P F+ + ++
Sbjct: 114 LYTPAPDIVHEAAGHAPILIHPEFSDYLRQ 143
>UniRef50_A7HE07 Cluster: Aromatic amino acid hydroxylase; n=5;
Cystobacterineae|Rep: Aromatic amino acid hydroxylase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/82 (37%), Positives = 41/82 (50%)
Frame = +3
Query: 156 FWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQP 335
+W+T E+GL + YGAGLLSS GE +CL+ E + Y IT QP
Sbjct: 213 YWWTAEYGLVGALDAPRLYGAGLLSSIGEAVHCLTPAVEKLPL-TAACADLAYDITRMQP 271
Query: 336 VYFVANSFEDAQEKMIKFAQTI 401
FVA F+ E + FA T+
Sbjct: 272 QLFVARDFDQLFEVLDGFAATL 293
Score = 46.4 bits (105), Expect = 7e-04
Identities = 18/43 (41%), Positives = 28/43 (65%), Gaps = 3/43 (6%)
Frame = +3
Query: 12 YTPEPDVCHELLGHAPLFADPAFAQF---SQEIGLASLGAPDD 131
YTP PD+ HE GHAP ADP +A++ + E+G ++ + +D
Sbjct: 120 YTPAPDIVHESAGHAPFIADPTYAEYLRRAGEVGFRAIASAED 162
>UniRef50_Q255G4 Cluster: Aromatic amino acid hyroxylase
biopterin-dependent; n=3; Chlamydophila|Rep: Aromatic
amino acid hyroxylase biopterin-dependent -
Chlamydophila felis (strain Fe/C-56)
Length = 279
Score = 54.8 bits (126), Expect = 2e-06
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 19/156 (12%)
Frame = +3
Query: 24 PDVCHELLGHAPLFADPAFAQFSQEIG---LASLG-APDDY-IEK-----------LATC 155
PD+ H+L H P P F F +G + S+ A + Y IE ++ C
Sbjct: 106 PDLIHDLFCHIPWLLHPEFVNFFSTMGELFVKSIKRAKEIYPIEDQPRILNSNALAISRC 165
Query: 156 FWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQP 335
FWFTVE GL ++G+ KAYGA +LSS +L + ++ + F E Q
Sbjct: 166 FWFTVESGLIEEQGKRKAYGAAVLSSTEQLSHTFNNNVFVSPFKTEHIIQRPCNPNAIQT 225
Query: 336 VYFVANSF---EDAQEKMIKFAQTIPRDFGVRYNPY 434
F+ F D +KM F + DF V + P+
Sbjct: 226 TLFIIRDFSELNDISKKMHLFLEKGRLDF-VVFGPH 260
>UniRef50_Q9Z6L3 Cluster: Probable aromatic amino acid hydroxylase;
n=2; Chlamydophila pneumoniae|Rep: Probable aromatic
amino acid hydroxylase - Chlamydia pneumoniae
(Chlamydophila pneumoniae)
Length = 362
Score = 54.4 bits (125), Expect = 3e-06
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 16/133 (12%)
Frame = +3
Query: 24 PDVCHELLGHAPLFADPAFAQFSQEIG---------LASLGAPDDYIEKLAT-------C 155
PD+ H+LLGH P P+F++F +G + +L + I+ L + C
Sbjct: 196 PDLIHDLLGHVPWLLHPSFSEFFINMGRLFTKVIEKVQALPSKKQRIQTLQSNLIAIVRC 255
Query: 156 FWFTVEFGLCRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQP 335
FWFTVE GL KAYGA L+SS EL + D + + + + + Q
Sbjct: 256 FWFTVESGLIENHEGRKAYGAVLISSPQELGHAFIDNVRVLPLELDQIIRLPFNTSTPQE 315
Query: 336 VYFVANSFEDAQE 374
F F++ E
Sbjct: 316 TLFSIRHFDELVE 328
>UniRef50_A4BFA1 Cluster: Probable aldose 1-epimerase; n=1; Reinekea
sp. MED297|Rep: Probable aldose 1-epimerase - Reinekea
sp. MED297
Length = 350
Score = 35.5 bits (78), Expect = 1.3
Identities = 15/41 (36%), Positives = 25/41 (60%)
Frame = +3
Query: 192 EGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKY 314
+G+L+ G+ L ++ G + CLSD+P L+ + GGT Y
Sbjct: 260 DGELRELGSALSTTNGVMMSCLSDQPGLQFYSGNFLGGTPY 300
>UniRef50_A1RK23 Cluster: CRISPR-associated helicase Cas3 family;
n=9; Gammaproteobacteria|Rep: CRISPR-associated helicase
Cas3 family - Shewanella sp. (strain W3-18-1)
Length = 1137
Score = 35.1 bits (77), Expect = 1.7
Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 4/86 (4%)
Frame = +3
Query: 18 PEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQE- 194
P+ D+C + + D A+ S+E G + DY ++L +CF F GL
Sbjct: 223 PDKDLCTDYKTESAASLDIMLARISKEWGYQNRYDEQDYEKRLKSCFRF--PNGLLSNSK 280
Query: 195 ---GQLKAYGAGLLSSFGELQYCLSD 263
Q+K + A LL ++Q CL+D
Sbjct: 281 PWLQQVKKWSARLLQQQTQVQQCLTD 306
>UniRef50_A1WTT4 Cluster: Putative Chase2 sensor protein precursor;
n=1; Halorhodospira halophila SL1|Rep: Putative Chase2
sensor protein precursor - Halorhodospira halophila
(strain DSM 244 / SL1) (Ectothiorhodospirahalophila
(strain DSM 244 / SL1))
Length = 670
Score = 34.7 bits (76), Expect = 2.2
Identities = 21/51 (41%), Positives = 25/51 (49%)
Frame = +3
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPV 338
R EGQ KAYG GLL + + L RE D G P+T Y+PV
Sbjct: 612 RVEGQTKAYGVGLLVT-EHTRAGLETVYGFREIDRIQVKGRSQPVTLYEPV 661
>UniRef50_Q81WA2 Cluster: Putative uncharacterized protein; n=1;
Bacillus anthracis|Rep: Putative uncharacterized protein
- Bacillus anthracis
Length = 203
Score = 33.1 bits (72), Expect = 6.7
Identities = 20/52 (38%), Positives = 29/52 (55%)
Frame = +3
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVY 341
R EG L Y G LS + E+ LSD P + ++ P++ K P T+ +PVY
Sbjct: 122 RFEG-LSVYDVGNLSRWREV---LSDNPNVVQYRPDNDNPDKQPYTKPKPVY 169
>UniRef50_Q4QIF4 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 440
Score = 33.1 bits (72), Expect = 6.7
Identities = 11/27 (40%), Positives = 21/27 (77%)
Frame = +3
Query: 327 YQPVYFVANSFEDAQEKMIKFAQTIPR 407
YQP++F+++S E+ E+++ F T+PR
Sbjct: 343 YQPMFFLSSSVENKAERIVYFPDTLPR 369
>UniRef50_A4VDS2 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1949
Score = 33.1 bits (72), Expect = 6.7
Identities = 15/36 (41%), Positives = 21/36 (58%)
Frame = +3
Query: 273 LREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKM 380
L EF+ + GGTK+ + EY P Y E+ QEK+
Sbjct: 453 LMEFEDKPIGGTKFVLDEYPPGYDPNAKKEETQEKL 488
>UniRef50_Q4RV58 Cluster: Chromosome 15 SCAF14992, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14992, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 286
Score = 32.7 bits (71), Expect = 8.9
Identities = 17/49 (34%), Positives = 24/49 (48%)
Frame = -2
Query: 181 RPNSTVNQKHVASFSM*SSGAPRDARPIS*ENCAKAGSAKSGACPSNSW 35
RP + +N K AS S + R S +C+ G A + ACP +SW
Sbjct: 206 RPRTRLNSKDCASLSE-RAAQTRTCWDGSCSSCSSPGQASASACPRHSW 253
>UniRef50_P88933 Cluster: ORF 45; n=3; Human herpesvirus 8|Rep: ORF
45 - Human herpesvirus 8 type M
Length = 407
Score = 32.7 bits (71), Expect = 8.9
Identities = 21/62 (33%), Positives = 33/62 (53%)
Frame = -2
Query: 190 CRHRPNSTVNQKHVASFSM*SSGAPRDARPIS*ENCAKAGSAKSGACPSNSWHTSGSGV* 11
C+ +PN +++K VAS + SSG+ D P S + + S+ G P+ S TS +
Sbjct: 314 CQRQPN--LSRKAVASVIIISSGSDTDEEPSSAVSVIVSPSSTKGHLPTQSPSTSAHSIS 371
Query: 10 SG 5
SG
Sbjct: 372 SG 373
>UniRef50_Q982K5 Cluster: Transposase; n=9; Alphaproteobacteria|Rep:
Transposase - Rhizobium loti (Mesorhizobium loti)
Length = 980
Score = 32.7 bits (71), Expect = 8.9
Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 399 IPRDFGVRYNPYTQSIDILDSARQIRVLMR-EVHQEMELLLN 521
+P+DFG+R + Y +D+ AR+ +R E+ +E+ LLLN
Sbjct: 485 LPKDFGIRRDAYYSGLDLTPDAREFTSAVRAELEREL-LLLN 525
>UniRef50_A3LQA7 Cluster: Putative uncharacterized protein; n=3;
Saccharomycetales|Rep: Putative uncharacterized protein
- Pichia stipitis (Yeast)
Length = 667
Score = 32.7 bits (71), Expect = 8.9
Identities = 18/45 (40%), Positives = 28/45 (62%)
Frame = +1
Query: 235 SASYSTVSQTNLS*ESLTPSLPGVPSIPSQNTSPSISLLTALKMP 369
S+S+ + S ++ S +LTP+ G PSI +TSPS S+ L+ P
Sbjct: 21 SSSFRSNSSSS-SFSNLTPTRSGPPSISHYSTSPSFSISVTLESP 64
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 699,048,338
Number of Sequences: 1657284
Number of extensions: 14015396
Number of successful extensions: 38452
Number of sequences better than 10.0: 65
Number of HSP's better than 10.0 without gapping: 36333
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38290
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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