Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0291
(698 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U49897-1|AAC51772.1| 452|Homo sapiens phenylalanine hydroxylase... 260 3e-69
K03020-1|AAA60082.1| 452|Homo sapiens phenylalanine hydroxylase... 260 3e-69
BC026251-1|AAH26251.1| 452|Homo sapiens phenylalanine hydroxyla... 260 3e-69
AF404777-1|AAL78816.1| 452|Homo sapiens phenylalanine hydroxyla... 259 6e-69
BC114499-1|AAI14500.1| 490|Homo sapiens tryptophan hydroxylase ... 232 1e-60
BC114442-1|AAI14443.1| 496|Homo sapiens TPH2 protein protein. 232 1e-60
AY098914-1|AAM28946.1| 490|Homo sapiens neuronal tryptophan hyd... 232 1e-60
L29306-1|AAA67050.1| 444|Homo sapiens tryptophan hydroxylase pr... 227 3e-59
X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for ... 226 7e-59
BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase ... 226 7e-59
BC104967-1|AAI04968.1| 497|Homo sapiens tyrosine hydroxylase pr... 226 7e-59
Y00414-1|CAA68472.1| 524|Homo sapiens protein ( Human mRNA for ... 224 3e-58
X05290-1|CAA28908.1| 497|Homo sapiens protein ( Human mRNA for ... 224 3e-58
M17589-1|AAA61179.1| 528|Homo sapiens TH protein. 224 3e-58
DQ677337-1|ABG73365.1| 407|Homo sapiens tyrosine hydroxylase is... 213 4e-55
DQ677336-1|ABG73364.1| 403|Homo sapiens tyrosine hydroxylase is... 213 4e-55
AY196344-1|AAO72075.1| 163|Homo sapiens tryptophan hydroxylase ... 210 4e-54
AY144494-1|AAN39538.1| 115|Homo sapiens putative tyrosine hydro... 118 3e-26
AY196346-1|AAO72076.1| 74|Homo sapiens tryptophan hydroxylase ... 76 1e-13
AF057280-2|AAC69458.1| 57|Homo sapiens tryptophan hydroxylase ... 51 3e-06
AF057280-1|AAC69459.1| 79|Homo sapiens tryptophan hydroxylase ... 50 6e-06
S61396-1|AAD13928.1| 26|Homo sapiens PAH protein. 44 4e-04
S61296-1|AAD13926.1| 25|Homo sapiens PAH protein. 37 0.060
AY722626-1|AAU11305.1| 23|Homo sapiens phenylalanine hydroxyla... 36 0.14
BC038402-1|AAH38402.1| 607|Homo sapiens ARP5 actin-related prot... 31 5.2
BC006162-1|AAH06162.1| 342|Homo sapiens ACTR5 protein protein. 31 5.2
BC001324-1|AAH01324.1| 415|Homo sapiens ACTR5 protein protein. 31 5.2
AL133519-2|CAD37358.1| 607|Homo sapiens ARP5 actin-related prot... 31 5.2
AK022847-1|BAB14270.1| 607|Homo sapiens protein ( Homo sapiens ... 31 5.2
EF215531-1|ABN11363.1| 293|Homo sapiens MHC class I antigen pro... 30 6.9
>U49897-1|AAC51772.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 260 bits (638), Expect = 3e-69
Identities = 113/178 (63%), Positives = 146/178 (82%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+P+YTPEPD+CHELLGH PLF+D +FAQFSQEIGLASLGAPD+YIEKLAT +WFTVEFGL
Sbjct: 274 KPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGL 333
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C+Q +KAYGAGLLSSFGELQYCLS+KP+L + E T Y +TE+QP+Y+VA SF
Sbjct: 334 CKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFN 393
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
DA+EK+ FA TIPR F VRY+PYTQ I++LD+ +Q+++L ++ E+ +L +A+ K+
Sbjct: 394 DAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKI 451
>K03020-1|AAA60082.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 260 bits (638), Expect = 3e-69
Identities = 113/178 (63%), Positives = 146/178 (82%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+P+YTPEPD+CHELLGH PLF+D +FAQFSQEIGLASLGAPD+YIEKLAT +WFTVEFGL
Sbjct: 274 KPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGL 333
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C+Q +KAYGAGLLSSFGELQYCLS+KP+L + E T Y +TE+QP+Y+VA SF
Sbjct: 334 CKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFN 393
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
DA+EK+ FA TIPR F VRY+PYTQ I++LD+ +Q+++L ++ E+ +L +A+ K+
Sbjct: 394 DAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKI 451
>BC026251-1|AAH26251.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 260 bits (638), Expect = 3e-69
Identities = 113/178 (63%), Positives = 146/178 (82%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+P+YTPEPD+CHELLGH PLF+D +FAQFSQEIGLASLGAPD+YIEKLAT +WFTVEFGL
Sbjct: 274 KPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGL 333
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C+Q +KAYGAGLLSSFGELQYCLS+KP+L + E T Y +TE+QP+Y+VA SF
Sbjct: 334 CKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFN 393
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
DA+EK+ FA TIPR F VRY+PYTQ I++LD+ +Q+++L ++ E+ +L +A+ K+
Sbjct: 394 DAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKI 451
>AF404777-1|AAL78816.1| 452|Homo sapiens phenylalanine hydroxylase
protein.
Length = 452
Score = 259 bits (635), Expect = 6e-69
Identities = 112/178 (62%), Positives = 146/178 (82%)
Frame = +3
Query: 3 RPLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGL 182
+P+YTP+PD+CHELLGH PLF+D +FAQFSQEIGLASLGAPD+YIEKLAT +WFTVEFGL
Sbjct: 274 KPMYTPQPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGL 333
Query: 183 CRQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFE 362
C+Q +KAYGAGLLSSFGELQYCLS+KP+L + E T Y +TE+QP+Y+VA SF
Sbjct: 334 CKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFN 393
Query: 363 DAQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
DA+EK+ FA TIPR F VRY+PYTQ I++LD+ +Q+++L ++ E+ +L +A+ K+
Sbjct: 394 DAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKI 451
>BC114499-1|AAI14500.1| 490|Homo sapiens tryptophan hydroxylase 2
protein.
Length = 490
Score = 232 bits (567), Expect = 1e-60
Identities = 105/177 (59%), Positives = 140/177 (79%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
PLYTPEPD CHELLGH PL ADP FAQFSQEIGLASLGA D+ ++KLATC++FT+EFGLC
Sbjct: 308 PLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLC 367
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+QEGQL+AYGAGLLSS GEL++ LSDK ++ FDP++T + IT +Q YFV+ SFE+
Sbjct: 368 KQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEE 427
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A+EKM FA++I R F V +NPYTQSI+IL R I +++++ ++ + +A++K+
Sbjct: 428 AKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484
>BC114442-1|AAI14443.1| 496|Homo sapiens TPH2 protein protein.
Length = 496
Score = 232 bits (567), Expect = 1e-60
Identities = 105/177 (59%), Positives = 140/177 (79%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
PLYTPEPD CHELLGH PL ADP FAQFSQEIGLASLGA D+ ++KLATC++FT+EFGLC
Sbjct: 314 PLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLC 373
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+QEGQL+AYGAGLLSS GEL++ LSDK ++ FDP++T + IT +Q YFV+ SFE+
Sbjct: 374 KQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEE 433
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A+EKM FA++I R F V +NPYTQSI+IL R I +++++ ++ + +A++K+
Sbjct: 434 AKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 490
>AY098914-1|AAM28946.1| 490|Homo sapiens neuronal tryptophan
hydroxylase protein.
Length = 490
Score = 232 bits (567), Expect = 1e-60
Identities = 105/177 (59%), Positives = 140/177 (79%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
PLYTPEPD CHELLGH PL ADP FAQFSQEIGLASLGA D+ ++KLATC++FT+EFGLC
Sbjct: 308 PLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLC 367
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+QEGQL+AYGAGLLSS GEL++ LSDK ++ FDP++T + IT +Q YFV+ SFE+
Sbjct: 368 KQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEE 427
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A+EKM FA++I R F V +NPYTQSI+IL R I +++++ ++ + +A++K+
Sbjct: 428 AKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484
>L29306-1|AAA67050.1| 444|Homo sapiens tryptophan hydroxylase
protein.
Length = 444
Score = 227 bits (555), Expect = 3e-59
Identities = 103/179 (57%), Positives = 139/179 (77%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD CHELLGH PL A+P+FAQFSQEIGLASLGA ++ ++KLATC++FTVEFGLC
Sbjct: 262 PFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLC 321
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q+GQL+ +GAGLLSS EL++ LS +++ FDP+ T + IT +Q VYFV+ SFED
Sbjct: 322 KQDGQLRVFGAGLLSSISELKHVLSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFED 381
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL*R 542
A+EKM +F +TI R FGV+YNPYT+SI IL A+ I M E+ +++++ +A+ K+ R
Sbjct: 382 AKEKMREFTKTIKRPFGVKYNPYTRSIQILKDAKSITNAMNELRHDLDVVSDALGKVSR 440
>X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for
tryptophan hydroxylase (EC 1.14.16.4). ).
Length = 444
Score = 226 bits (552), Expect = 7e-59
Identities = 102/179 (56%), Positives = 138/179 (77%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD CHELLGH PL A+P+FAQFSQEIGLASLGA ++ ++KLATC++FTVEFGLC
Sbjct: 262 PFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLC 321
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q+GQL+ +GAGLLSS EL++ LS +++ FDP+ T + IT +Q VYFV+ SFED
Sbjct: 322 KQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFED 381
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL*R 542
A+EKM +F +TI R FGV+YNPYT+SI IL + I M E+ +++++ +A+ K+ R
Sbjct: 382 AKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKVSR 440
>BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase 1
(tryptophan 5-monooxygenase) protein.
Length = 444
Score = 226 bits (552), Expect = 7e-59
Identities = 102/179 (56%), Positives = 138/179 (77%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD CHELLGH PL A+P+FAQFSQEIGLASLGA ++ ++KLATC++FTVEFGLC
Sbjct: 262 PFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLC 321
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q+GQL+ +GAGLLSS EL++ LS +++ FDP+ T + IT +Q VYFV+ SFED
Sbjct: 322 KQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFED 381
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL*R 542
A+EKM +F +TI R FGV+YNPYT+SI IL + I M E+ +++++ +A+ K+ R
Sbjct: 382 AKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKVSR 440
>BC104967-1|AAI04968.1| 497|Homo sapiens tyrosine hydroxylase
protein.
Length = 497
Score = 226 bits (552), Expect = 7e-59
Identities = 99/177 (55%), Positives = 134/177 (75%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T +WFTVEFGLC
Sbjct: 320 PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLC 379
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q G++KAYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF D
Sbjct: 380 KQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSD 439
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A++K+ +A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 440 AKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 496
>Y00414-1|CAA68472.1| 524|Homo sapiens protein ( Human mRNA for
tyrosine hydroxylase type 3. ).
Length = 524
Score = 224 bits (547), Expect = 3e-58
Identities = 99/177 (55%), Positives = 133/177 (75%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T WFTVEFGLC
Sbjct: 347 PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLC 406
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q G++KAYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF D
Sbjct: 407 KQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSD 466
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A++K+ +A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 467 AKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 523
>X05290-1|CAA28908.1| 497|Homo sapiens protein ( Human mRNA for
tyrosine hydroxylase (HTH-1). ).
Length = 497
Score = 224 bits (547), Expect = 3e-58
Identities = 99/177 (55%), Positives = 133/177 (75%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T WFTVEFGLC
Sbjct: 320 PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLC 379
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q G++KAYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF D
Sbjct: 380 KQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSD 439
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A++K+ +A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 440 AKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 496
>M17589-1|AAA61179.1| 528|Homo sapiens TH protein.
Length = 528
Score = 224 bits (547), Expect = 3e-58
Identities = 99/177 (55%), Positives = 133/177 (75%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P+++PEPD CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T WFTVEFGLC
Sbjct: 351 PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLC 410
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q G++KAYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF D
Sbjct: 411 KQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSD 470
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
A++K+ +A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 471 AKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 527
>DQ677337-1|ABG73365.1| 407|Homo sapiens tyrosine hydroxylase
isoform D2,8,9 protein.
Length = 407
Score = 213 bits (521), Expect = 4e-55
Identities = 95/170 (55%), Positives = 127/170 (74%)
Frame = +3
Query: 27 DVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQEGQLK 206
D CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T +WFTVEFGLC+Q G++K
Sbjct: 237 DCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVK 296
Query: 207 AYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKMIK 386
AYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF DA++K+
Sbjct: 297 AYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRS 356
Query: 387 FAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
+A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 357 YASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 406
>DQ677336-1|ABG73364.1| 403|Homo sapiens tyrosine hydroxylase
isoform D1b,2,8,9 protein.
Length = 403
Score = 213 bits (521), Expect = 4e-55
Identities = 95/170 (55%), Positives = 127/170 (74%)
Frame = +3
Query: 27 DVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQEGQLK 206
D CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T +WFTVEFGLC+Q G++K
Sbjct: 233 DCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVK 292
Query: 207 AYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKMIK 386
AYGAGLLSS+GEL +CLS++PE+R FDPE+ Y YQ VYFV+ SF DA++K+
Sbjct: 293 AYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRS 352
Query: 387 FAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL 536
+A I R F V+++PYT +ID+LDS + +R + V E++ L +A+ +
Sbjct: 353 YASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 402
>AY196344-1|AAO72075.1| 163|Homo sapiens tryptophan hydroxylase
protein.
Length = 163
Score = 210 bits (513), Expect = 4e-54
Identities = 95/154 (61%), Positives = 122/154 (79%)
Frame = +3
Query: 6 PLYTPEPDVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLC 185
P YTPEPD CHELLGH PL A+P+FAQFSQEIGLASLGA ++ ++KLATC++FTVEFGLC
Sbjct: 9 PFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLC 68
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFED 365
+Q+GQL+ +GAGLLSS EL++ LS +++ FDP+ T + IT +Q VYFV+ SFED
Sbjct: 69 KQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFED 128
Query: 366 AQEKMIKFAQTIPRDFGVRYNPYTQSIDILDSAR 467
A+EKM +F +TI R GV+YNPYT+SI IL +
Sbjct: 129 AKEKMREFTKTIKRPPGVKYNPYTRSIQILKDTK 162
>AY144494-1|AAN39538.1| 115|Homo sapiens putative tyrosine
hydroxylase variant protein.
Length = 115
Score = 118 bits (283), Expect = 3e-26
Identities = 52/70 (74%), Positives = 60/70 (85%)
Frame = +3
Query: 27 DVCHELLGHAPLFADPAFAQFSQEIGLASLGAPDDYIEKLATCFWFTVEFGLCRQEGQLK 206
D CHELLGH P+ AD FAQFSQ+IGLASLGA D+ IEKL+T WFTVEFGLC+Q G++K
Sbjct: 46 DCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLCKQNGEVK 105
Query: 207 AYGAGLLSSF 236
AYGAGLLSS+
Sbjct: 106 AYGAGLLSSY 115
>AY196346-1|AAO72076.1| 74|Homo sapiens tryptophan hydroxylase
protein.
Length = 74
Score = 75.8 bits (178), Expect = 1e-13
Identities = 36/73 (49%), Positives = 50/73 (68%)
Frame = +3
Query: 249 YCLSDKPELREFDPESTGGTKYPITEYQPVYFVANSFEDAQEKMIKFAQTIPRDFGVRYN 428
+ LS +++ FDP+ T + IT +Q VYFV+ SFEDA+EKM + +TI R FGV+YN
Sbjct: 1 HALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMRESTKTIKRPFGVKYN 60
Query: 429 PYTQSIDILDSAR 467
PYT+SI IL +
Sbjct: 61 PYTRSIQILKDTK 73
>AF057280-2|AAC69458.1| 57|Homo sapiens tryptophan hydroxylase
isoform 1 protein.
Length = 57
Score = 51.2 bits (117), Expect = 3e-06
Identities = 22/53 (41%), Positives = 36/53 (67%)
Frame = +3
Query: 384 KFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDKL*R 542
+F +TI R FGV+YNPYT+SI IL + I M E+ +++++ +A+ K+ R
Sbjct: 1 EFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKVSR 53
>AF057280-1|AAC69459.1| 79|Homo sapiens tryptophan hydroxylase
isoform 2 protein.
Length = 79
Score = 50.4 bits (115), Expect = 6e-06
Identities = 21/50 (42%), Positives = 34/50 (68%)
Frame = +3
Query: 384 KFAQTIPRDFGVRYNPYTQSIDILDSARQIRVLMREVHQEMELLLNAMDK 533
+F +TI R FGV+YNPYT+SI IL + I M E+ +++++ +A+ K
Sbjct: 1 EFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAK 50
>S61396-1|AAD13928.1| 26|Homo sapiens PAH protein.
Length = 26
Score = 44.4 bits (100), Expect = 4e-04
Identities = 17/25 (68%), Positives = 20/25 (80%)
Frame = +3
Query: 141 KLATCFWFTVEFGLCRQEGQLKAYG 215
KLAT +WFTVEFG C+Q +KAYG
Sbjct: 1 KLATIYWFTVEFGFCKQGDSIKAYG 25
>S61296-1|AAD13926.1| 25|Homo sapiens PAH protein.
Length = 25
Score = 37.1 bits (82), Expect = 0.060
Identities = 15/25 (60%), Positives = 20/25 (80%)
Frame = +3
Query: 324 EYQPVYFVANSFEDAQEKMIKFAQT 398
E+QP+Y+VA SF DA+EK+ FA T
Sbjct: 1 EFQPLYYVAGSFNDAKEKVRNFAAT 25
>AY722626-1|AAU11305.1| 23|Homo sapiens phenylalanine hydroxylase
protein.
Length = 23
Score = 35.9 bits (79), Expect = 0.14
Identities = 13/23 (56%), Positives = 19/23 (82%)
Frame = +3
Query: 312 YPITEYQPVYFVANSFEDAQEKM 380
Y +TE+QP+Y+VA SF D +EK+
Sbjct: 1 YTVTEFQPLYYVAESFNDDKEKV 23
>BC038402-1|AAH38402.1| 607|Homo sapiens ARP5 actin-related protein
5 homolog (yeast) protein.
Length = 607
Score = 30.7 bits (66), Expect = 5.2
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Frame = +3
Query: 240 ELQYCLSDKPELREFDP---ESTGGTKYPITEYQPVYFVA 350
+L+ L D + +FDP E T G + P+T QPV+ +A
Sbjct: 398 QLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLA 437
>BC006162-1|AAH06162.1| 342|Homo sapiens ACTR5 protein protein.
Length = 342
Score = 30.7 bits (66), Expect = 5.2
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Frame = +3
Query: 240 ELQYCLSDKPELREFDP---ESTGGTKYPITEYQPVYFVA 350
+L+ L D + +FDP E T G + P+T QPV+ +A
Sbjct: 133 QLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLA 172
>BC001324-1|AAH01324.1| 415|Homo sapiens ACTR5 protein protein.
Length = 415
Score = 30.7 bits (66), Expect = 5.2
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Frame = +3
Query: 240 ELQYCLSDKPELREFDP---ESTGGTKYPITEYQPVYFVA 350
+L+ L D + +FDP E T G + P+T QPV+ +A
Sbjct: 206 QLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLA 245
>AL133519-2|CAD37358.1| 607|Homo sapiens ARP5 actin-related protein
5 homolog (yeast) protein.
Length = 607
Score = 30.7 bits (66), Expect = 5.2
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Frame = +3
Query: 240 ELQYCLSDKPELREFDP---ESTGGTKYPITEYQPVYFVA 350
+L+ L D + +FDP E T G + P+T QPV+ +A
Sbjct: 398 QLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLA 437
>AK022847-1|BAB14270.1| 607|Homo sapiens protein ( Homo sapiens
cDNA FLJ12785 fis, clone NT2RP2001900, weakly similar to
ACTIN-LIKE PROTEIN ARP5. ).
Length = 607
Score = 30.7 bits (66), Expect = 5.2
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Frame = +3
Query: 240 ELQYCLSDKPELREFDP---ESTGGTKYPITEYQPVYFVA 350
+L+ L D + +FDP E T G + P+T QPV+ +A
Sbjct: 398 QLEPSLEDVESMNDFDPLFSEETPGVEKPVTTVQPVFNLA 437
>EF215531-1|ABN11363.1| 293|Homo sapiens MHC class I antigen
protein.
Length = 293
Score = 30.3 bits (65), Expect = 6.9
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = +3
Query: 186 RQEGQLKAYGAGLLSSFGELQYCLSDKPELREFDPESTGGTKYPITEYQ 332
R+ QL+AY AGL + +Y + K L+ DP T T +PI++++
Sbjct: 150 REAEQLRAYLAGLCVEWLR-RYLENGKETLQRADPPKTHVTHHPISDHE 197
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,045,090
Number of Sequences: 237096
Number of extensions: 2103692
Number of successful extensions: 5425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5166
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5415
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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