SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= an--0170
         (717 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;...   186   4e-46
UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;...   185   1e-45
UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G...   169   4e-41
UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat...   152   1e-35
UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu...   130   4e-29
UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase...   126   5e-28
UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ...   118   2e-25
UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat...   116   4e-25
UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh...   115   1e-24
UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re...   114   2e-24
UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos...   114   2e-24
UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy...   113   3e-24
UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;...   113   4e-24
UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat...   113   5e-24
UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill...   112   7e-24
UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,...   112   7e-24
UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl...   112   9e-24
UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   109   9e-23
UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...   109   9e-23
UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ...   107   2e-22
UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola...   103   3e-21
UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl...   101   2e-20
UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ...    96   9e-19
UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat...    75   1e-18
UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve...    93   8e-18
UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat...    92   1e-17
UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    92   1e-17
UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep...    91   2e-17
UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ...    90   6e-17
UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;...    89   1e-16
UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep: H...    87   4e-16
UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc...    87   4e-16
UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    86   7e-16
UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola...    85   2e-15
UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    83   5e-15
UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ...    83   5e-15
UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ...    83   7e-15
UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr...    82   1e-14
UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ...    82   2e-14
UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola...    82   2e-14
UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot...    81   3e-14
UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox...    79   1e-13
UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    79   1e-13
UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion...    78   2e-13
UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola...    77   4e-13
UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo...    77   6e-13
UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    75   2e-12
UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit...    75   2e-12
UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ...    75   2e-12
UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000...    74   3e-12
UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat...    74   4e-12
UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    72   1e-11
UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot...    72   2e-11
UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola...    72   2e-11
UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    71   3e-11
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri...    71   4e-11
UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    71   4e-11
UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ...    70   5e-11
UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;...    70   5e-11
UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox...    70   5e-11
UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot...    70   5e-11
UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur...    70   5e-11
UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who...    70   7e-11
UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat...    69   2e-10
UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur...    68   3e-10
UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase, putat...    68   3e-10
UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    66   6e-10
UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrola...    66   6e-10
UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome sh...    65   1e-09
UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    65   2e-09
UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfami...    64   2e-09
UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    64   4e-09
UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrola...    64   4e-09
UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat...    63   6e-09
UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrola...    63   8e-09
UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; ...    63   8e-09
UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrola...    63   8e-09
UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ...    62   1e-08
UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur...    62   1e-08
UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo...    62   2e-08
UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    62   2e-08
UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrola...    62   2e-08
UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola...    61   2e-08
UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas...    61   3e-08
UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    61   3e-08
UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    60   4e-08
UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot...    60   4e-08
UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione ...    60   7e-08
UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat...    60   7e-08
UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organ...    60   7e-08
UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9; ...    59   9e-08
UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    59   9e-08
UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; ...    59   9e-08
UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3; ...    59   9e-08
UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprot...    59   9e-08
UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,...    59   1e-07
UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaprot...    59   1e-07
UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    58   2e-07
UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily prot...    58   2e-07
UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ...    57   4e-07
UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ...    57   4e-07
UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily hydr...    57   4e-07
UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syn...    56   9e-07
UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met...    56   1e-06
UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily prot...    56   1e-06
UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; ...    56   1e-06
UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    56   1e-06
UniRef50_Q0RV06 Cluster: Possible hydrolase; n=11; Actinomycetal...    56   1e-06
UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola...    55   2e-06
UniRef50_A5INW0 Cluster: Beta-lactamase domain protein; n=30; St...    55   2e-06
UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrola...    55   2e-06
UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira...    54   4e-06
UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter...    54   4e-06
UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    54   4e-06
UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c...    54   4e-06
UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ...    54   5e-06
UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clo...    54   5e-06
UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily prot...    54   5e-06
UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamil...    53   8e-06
UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    53   8e-06
UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2; sul...    52   1e-05
UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1; Met...    52   1e-05
UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5; ...    52   1e-05
UniRef50_Q71KM2 Cluster: Glyoxalase II; n=8; Plasmodium|Rep: Gly...    52   2e-05
UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular o...    52   2e-05
UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; ...    51   2e-05
UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrola...    51   3e-05
UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; ...    50   4e-05
UniRef50_A6BZ99 Cluster: Putative uncharacterized protein; n=2; ...    50   4e-05
UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; ...    50   6e-05
UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily prot...    50   6e-05
UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot...    50   6e-05
UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ...    50   8e-05
UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    49   1e-04
UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosar...    49   1e-04
UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2...    48   2e-04
UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily prot...    48   2e-04
UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon...    48   2e-04
UniRef50_Q1AVJ8 Cluster: Beta-lactamase-like protein; n=4; Bacte...    48   3e-04
UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=1...    47   5e-04
UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4...    47   5e-04
UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus...    47   5e-04
UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acine...    46   7e-04
UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Hal...    46   7e-04
UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Ac...    46   0.001
UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, wh...    46   0.001
UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; ...    46   0.001
UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba...    45   0.002
UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily prot...    45   0.002
UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein; ...    45   0.002
UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-P...    45   0.002
UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syn...    45   0.002
UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bac...    44   0.003
UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; ...    44   0.003
UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti...    44   0.003
UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2; Chloroflexus|...    44   0.003
UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase relate...    44   0.003
UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate sulfurtransfer...    44   0.003
UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrola...    44   0.004
UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Can...    44   0.004
UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like d...    44   0.004
UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|R...    44   0.005
UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; ...    44   0.005
UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16; Proteobacter...    44   0.005
UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1; ...    44   0.005
UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Vic...    44   0.005
UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; ...    43   0.007
UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20; P...    43   0.007
UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyo...    43   0.009
UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia gloss...    43   0.009
UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1; Rubro...    43   0.009
UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2; Ros...    43   0.009
UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1; ...    43   0.009
UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas s...    42   0.011
UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein; ...    42   0.011
UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1; Sol...    42   0.011
UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep...    42   0.011
UniRef50_Q81Q95 Cluster: Metallo-beta-lactamase/rhodanese-like d...    42   0.015
UniRef50_Q1AUZ4 Cluster: Beta-lactamase-like protein; n=1; Rubro...    42   0.015
UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cy...    42   0.015
UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; ...    42   0.015
UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione hydro...    42   0.020
UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alk...    42   0.020
UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1; Mar...    42   0.020
UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;...    42   0.020
UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    41   0.027
UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep: Hyd...    41   0.027
UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3; ...    41   0.027
UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bac...    41   0.027
UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; ...    41   0.035
UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor...    41   0.035
UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;...    41   0.035
UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; ...    40   0.046
UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium di...    40   0.046
UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n...    40   0.061
UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrola...    40   0.061
UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1...    40   0.061
UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11; Ga...    40   0.061
UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein; ...    40   0.061
UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120; Ba...    40   0.081
UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Re...    39   0.11 
UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Re...    39   0.11 
UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1; ...    39   0.11 
UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clo...    39   0.11 
UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; ...    39   0.11 
UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: Yqg...    39   0.11 
UniRef50_Q4WA58 Cluster: Metallo-beta-lactamase domain protein; ...    39   0.11 
UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2; Ana...    39   0.14 
UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    39   0.14 
UniRef50_A4S568 Cluster: Predicted protein; n=1; Ostreococcus lu...    39   0.14 
UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37; Actinomyceta...    38   0.19 
UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    38   0.19 
UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium p...    38   0.19 
UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; ...    38   0.19 
UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bac...    38   0.19 
UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium c...    38   0.19 
UniRef50_Q7QZA0 Cluster: GLP_567_43928_43275; n=1; Giardia lambl...    38   0.19 
UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon...    38   0.25 
UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily prot...    38   0.25 
UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clost...    38   0.25 
UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    38   0.33 
UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; ...    38   0.33 
UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bac...    38   0.33 
UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1...    38   0.33 
UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    38   0.33 
UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region f...    37   0.43 
UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; ...    37   0.43 
UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1; ...    37   0.43 
UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; ...    37   0.57 
UniRef50_Q1VZM6 Cluster: Metallo-beta-lactamase superfamily prot...    37   0.57 
UniRef50_A1D100 Cluster: FAD binding domain protein; n=4; Tricho...    37   0.57 
UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; ...    36   0.76 
UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein; ...    36   0.76 
UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalterom...    36   0.76 
UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; She...    36   0.76 
UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1; Pseud...    36   0.76 
UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; ...    36   0.76 
UniRef50_A3L9H1 Cluster: Putative uncharacterized protein; n=1; ...    36   0.76 
UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; ...    36   0.76 
UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1; ...    36   0.76 
UniRef50_A3CRI7 Cluster: Beta-lactamase domain protein; n=3; Met...    36   0.76 
UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase fam...    36   1.00 
UniRef50_Q0RV20 Cluster: Possible hydrolase; n=1; Rhodococcus sp...    36   1.00 
UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1; Cal...    36   1.00 
UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1; The...    36   1.00 
UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syn...    36   1.00 
UniRef50_A4QPZ2 Cluster: Putative uncharacterized protein; n=4; ...    36   1.00 
UniRef50_UPI00015978D7 Cluster: NrsD; n=1; Bacillus amyloliquefa...    36   1.3  
UniRef50_UPI000023EAC6 Cluster: hypothetical protein FG07959.1; ...    36   1.3  
UniRef50_A1ZPC4 Cluster: Metallo-beta-lactamase family protein; ...    36   1.3  
UniRef50_Q188Q8 Cluster: Putative hydrolase; n=2; Clostridium di...    35   1.7  
UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo...    35   1.7  
UniRef50_Q24F45 Cluster: Hydroxyacylglutathione hydrolase, putat...    35   1.7  
UniRef50_Q4W945 Cluster: Metallo-beta-lactamase domain protein; ...    35   1.7  
UniRef50_Q8TUW9 Cluster: Zn-dependent hydrolase; n=1; Methanopyr...    35   1.7  
UniRef50_A4YDP4 Cluster: Beta-lactamase domain protein; n=1; Met...    35   1.7  
UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1; ...    35   2.3  
UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5; B...    35   2.3  
UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione hydro...    35   2.3  
UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4; Deino...    35   2.3  
UniRef50_A5URH7 Cluster: Beta-lactamase domain protein; n=4; Chl...    35   2.3  
UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein; ...    35   2.3  
UniRef50_A0LDZ9 Cluster: Beta-lactamase domain protein; n=1; Mag...    35   2.3  
UniRef50_A0B5Y5 Cluster: Beta-lactamase domain protein; n=1; Met...    35   2.3  
UniRef50_Q8NU87 Cluster: Zn-dependent hydrolases, including glyo...    34   3.0  
UniRef50_A1SFV7 Cluster: Beta-lactamase domain protein; n=1; Noc...    34   3.0  
UniRef50_Q5KE04 Cluster: Putative uncharacterized protein; n=2; ...    34   3.0  
UniRef50_Q2CF40 Cluster: Hydrolase 11; n=1; Oceanicola granulosu...    34   4.0  
UniRef50_Q1IQE8 Cluster: Beta-lactamase-like; n=2; Acidobacteria...    34   4.0  
UniRef50_A7ISC4 Cluster: HagH; n=5; Neisseria|Rep: HagH - Neisse...    34   4.0  
UniRef50_A5WCY4 Cluster: Beta-lactamase domain protein; n=5; Pro...    34   4.0  
UniRef50_UPI000050F771 Cluster: COG0491: Zn-dependent hydrolases...    33   5.3  
UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein; ...    33   5.3  
UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121; Proteobacte...    33   5.3  
UniRef50_Q4WQZ6 Cluster: Metallo-beta-lactamase domain protein, ...    33   5.3  
UniRef50_Q4WA79 Cluster: Metallo-beta-lactamase domain protein, ...    33   5.3  
UniRef50_O30264 Cluster: Putative uncharacterized protein; n=1; ...    33   5.3  
UniRef50_O28526 Cluster: Putative uncharacterized protein; n=1; ...    33   5.3  
UniRef50_Q9ACM3 Cluster: Cytosine-specific methyltransferase; n=...    33   7.0  
UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Ros...    33   7.0  
UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3; Deh...    33   7.0  
UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-l...    33   7.0  
UniRef50_Q2U887 Cluster: Glyoxylase; n=2; Trichocomaceae|Rep: Gl...    33   7.0  
UniRef50_A7D422 Cluster: Beta-lactamase domain protein; n=2; Hal...    33   7.0  
UniRef50_A5YSG8 Cluster: Thiosulfate sulfurtransferase/hydrolase...    33   7.0  
UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1; A...    33   7.0  
UniRef50_UPI0000499269 Cluster: metallo-beta-lactamase superfami...    33   9.3  
UniRef50_Q73QI1 Cluster: Metallo-beta-lactamase family protein; ...    33   9.3  
UniRef50_Q1ARM7 Cluster: Beta-lactamase-like protein; n=1; Rubro...    33   9.3  
UniRef50_Q0AZS8 Cluster: Putative uncharacterized protein; n=1; ...    33   9.3  
UniRef50_A1ZW49 Cluster: Putative uncharacterized protein; n=1; ...    33   9.3  
UniRef50_A0LWF9 Cluster: Beta-lactamase domain protein; n=1; Aci...    33   9.3  
UniRef50_Q8MR51 Cluster: GH20064p; n=5; Diptera|Rep: GH20064p - ...    33   9.3  
UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lambl...    33   9.3  
UniRef50_A2DZQ6 Cluster: Metallo-beta-lactamase superfamily prot...    33   9.3  
UniRef50_Q2UI96 Cluster: Zn-dependent hydrolases; n=4; Pezizomyc...    33   9.3  

>UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus
           musculus (Mouse)
          Length = 260

 Score =  186 bits (454), Expect = 4e-46
 Identities = 84/145 (57%), Positives = 107/145 (73%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M V++LPAL DNYMYLI+D+ T+EAAIVDPV+P+ V++A ++  V L            A
Sbjct: 1   MKVELLPALTDNYMYLIIDEDTQEAAIVDPVQPQKVIEAAKKHHVKLTTVLTTHHHWDHA 60

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           GGNE L+K  PGL VYGGDDRIGALT KV H +  ++G+L+V+CL TPCHT+GHICYFV+
Sbjct: 61  GGNEKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVS 120

Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708
            P     S VFTGDTLF+ GCG+F+
Sbjct: 121 KPGSSEPSAVFTGDTLFVAGCGKFY 145


>UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;
           Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo
           sapiens (Human)
          Length = 260

 Score =  185 bits (450), Expect = 1e-45
 Identities = 83/145 (57%), Positives = 103/145 (71%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M V++LPAL DNYMYL++D  TKEAAIVDPV+P+ V+ A  + GV L            A
Sbjct: 1   MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHA 60

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           GGNE L+K   GL VYGGDDRIGALT K+ H +  ++G+LNV+CL TPCHT+GHICYFV+
Sbjct: 61  GGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVS 120

Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708
            P       VFTGDTLF+ GCG+F+
Sbjct: 121 KPGGSEPPAVFTGDTLFVAGCGKFY 145


>UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep:
           Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito)
          Length = 302

 Score =  169 bits (412), Expect = 4e-41
 Identities = 91/194 (46%), Positives = 114/194 (58%), Gaps = 7/194 (3%)
 Frame = +1

Query: 148 LARFVNSLPSGLSQRITKLYFRALIRNQREAHSSQEDHQYKNMDVKILPALQDNYMYLIV 327
           ++  +N LP  LSQ +T  YF     + R   ++ +      M VK +PAL+DN+MYL+V
Sbjct: 1   MSALLNRLPHRLSQGLTAAYFTVNSWSIRRRSTAVQTTDMTRMTVKKIPALKDNFMYLVV 60

Query: 328 DKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG------ 489
              TK AAIVDPVEP  VL+  +E GV+L            AGGN DL K          
Sbjct: 61  CNETKNAAIVDPVEPDRVLQVAKESGVSLNKVLTTHHHWDHAGGNADLFKRYQADTSLGP 120

Query: 490 LIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVF 666
           L +YGG D+RI  LT  V  +   +IGNL V+C+ TPCHTT HICY++  PE   D VVF
Sbjct: 121 LQIYGGNDERIDNLTNPVGQDDTLEIGNLKVRCISTPCHTTSHICYYIETPE---DKVVF 177

Query: 667 TGDTLFLGGCGRFF 708
           TGDTLFL GCGRFF
Sbjct: 178 TGDTLFLAGCGRFF 191


>UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase,
           putative, expressed; n=3; Oryza sativa|Rep:
           Hydroxyacylglutathione hydrolase, putative, expressed -
           Oryza sativa subsp. japonica (Rice)
          Length = 258

 Score =  152 bits (368), Expect = 1e-35
 Identities = 76/147 (51%), Positives = 96/147 (65%), Gaps = 4/147 (2%)
 Frame = +1

Query: 280 VKILPA--LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +KI+P   L+DNY YLIVD++TK AA VDPVEP+ VL A  E GV +            A
Sbjct: 1   MKIIPVACLEDNYAYLIVDESTKSAAAVDPVEPEKVLAAAAEVGVRIDCVLTTHHHWDHA 60

Query: 454 GGNEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHICYF 627
           GGNE + +  PG+ VYGG  D +   T +VE+ TK  +G ++ + CL TPCHT GHI Y+
Sbjct: 61  GGNEKMAQSVPGIKVYGGSLDNVKGCTDQVENGTKLSLGKDIEILCLHTPCHTKGHISYY 120

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           VT+ EE  D  VFTGDTLF+ GCGRFF
Sbjct: 121 VTSKEE-EDPAVFTGDTLFIAGCGRFF 146


>UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24;
           Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo
           sapiens (Human)
          Length = 291

 Score =  130 bits (313), Expect = 4e-29
 Identities = 58/142 (40%), Positives = 89/142 (62%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M VK++P L+DNYMYL++++ T+EA  VD   PK +L+ V  +GV+L            A
Sbjct: 1   MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
            GN +L + RPGL V G D+RI +LT+++ H  + + G ++V+CL TP HT GH+ YF+ 
Sbjct: 61  RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLW 120

Query: 634 APEEGNDSVVFTGDTLFLGGCG 699
             +  +   +F+GD L + GCG
Sbjct: 121 EDDCPDPPALFSGDALSVAGCG 142


>UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase
           II, partial; n=1; Pan troglodytes|Rep: PREDICTED:
           similar to glyoxalase II, partial - Pan troglodytes
          Length = 284

 Score =  126 bits (304), Expect = 5e-28
 Identities = 53/86 (61%), Positives = 67/86 (77%)
 Frame = +1

Query: 451 AGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           AGGNE L++ + GL VYGGDDRIGALT K+ H +  ++G+LNV+CL TPCHT+GHICYFV
Sbjct: 3   AGGNEKLVELQSGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFV 62

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
           + P       VFTGDTLF+ GCG+F+
Sbjct: 63  SKPGGSEPPAVFTGDTLFVAGCGKFY 88


>UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 260

 Score =  118 bits (283), Expect = 2e-25
 Identities = 56/146 (38%), Positives = 84/146 (57%), Gaps = 3/146 (2%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAI-VDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           VK L    DN+MY++   +   AA+ VD V  +   +  +++ +++             G
Sbjct: 4   VKSLLRRADNFMYIVKKSSEARAALLVDLVNEEDYKELADKENIDITAVLTTHHHYDHCG 63

Query: 457 GNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636
           GNE   ++ P +++ GGD RI A+ + V+H    +   L ++CL TPCHT+GHICY +T 
Sbjct: 64  GNEGFRRQFPNVMILGGDSRIPAMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITN 123

Query: 637 PEEGNDS--VVFTGDTLFLGGCGRFF 708
           P   + S  VVFTGDTLF+ GCGRFF
Sbjct: 124 PAADSTSPGVVFTGDTLFIAGCGRFF 149


>UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione
           hydrolase, putative - Babesia bovis
          Length = 319

 Score =  116 bits (280), Expect = 4e-25
 Identities = 53/146 (36%), Positives = 85/146 (58%), Gaps = 2/146 (1%)
 Frame = +1

Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           +V  +P  QDNY Y++VD   K A  VDP EP+ +L  ++E+ + L            +G
Sbjct: 68  EVITVPLFQDNYGYIVVDPDGKHAFCVDPAEPRKILSVIDERKLTLKAVFCTHKHHDHSG 127

Query: 457 GNEDLIKERPGLIVYGGDDR-IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           GN ++ +  PG+ VYG ++  +  +T  +      ++G L ++ +  PCHT GH+ Y+VT
Sbjct: 128 GNLEMARIIPGIPVYGSNNEDMAGMTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVT 187

Query: 634 APEEGN-DSVVFTGDTLFLGGCGRFF 708
            P +     ++FTGDT+F+GGCGRFF
Sbjct: 188 NPSDPTMQPLMFTGDTIFIGGCGRFF 213


>UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 2
           SCAF14661, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 400

 Score =  115 bits (276), Expect = 1e-24
 Identities = 59/175 (33%), Positives = 90/175 (51%), Gaps = 5/175 (2%)
 Frame = +1

Query: 190 RITKLYFRALIRNQRE----AHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIV 357
           R+  +Y++  ++  RE     HS+ +      + +  +  L DNY YL++D A   A +V
Sbjct: 23  RLGYMYYKRQMKKARELYPAGHSTAQPCDLNGIKIIPISVLSDNYSYLVIDTAAGVAVVV 82

Query: 358 DPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTK 534
           DP +P+TV   ++E+GV L            +GGN++L K      VYG   D I  LT 
Sbjct: 83  DPADPQTVQAVIKEEGVVLEAILCTHKHWDHSGGNKELKKLHTSCRVYGSATDNIPGLTH 142

Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
            + H      G L+ + LFTP HT GH+ Y +     G+ S +F+GD +FL GCG
Sbjct: 143 PLSHRDSIAFGRLHFEALFTPGHTVGHMIYLLDGRTVGSPSSLFSGDLVFLSGCG 197


>UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep:
           Isoform 3 of Q8N490 - Homo sapiens (Human)
          Length = 361

 Score =  114 bits (275), Expect = 2e-24
 Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
 Frame = +1

Query: 202 LYFRALIRNQR----EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVE 369
           L++R  +R  R    + HS  +   +  + V  +P L DNY YLI+D   + A  VDP +
Sbjct: 67  LFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSD 126

Query: 370 PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTKKVEH 546
           P+ V  ++E++GV L            +GGN DL +      VYG   D I  LT  + H
Sbjct: 127 PRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCH 186

Query: 547 NTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
                +G L ++ L TP HT GH+ Y +        S +F+GD LFL GCGR F
Sbjct: 187 QDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF 240


>UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25;
           Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens
           (Human)
          Length = 385

 Score =  114 bits (275), Expect = 2e-24
 Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
 Frame = +1

Query: 202 LYFRALIRNQR----EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVE 369
           L++R  +R  R    + HS  +   +  + V  +P L DNY YLI+D   + A  VDP +
Sbjct: 91  LFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSD 150

Query: 370 PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTKKVEH 546
           P+ V  ++E++GV L            +GGN DL +      VYG   D I  LT  + H
Sbjct: 151 PRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCH 210

Query: 547 NTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
                +G L ++ L TP HT GH+ Y +        S +F+GD LFL GCGR F
Sbjct: 211 QDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF 264


>UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20;
           Ascomycota|Rep: Function: RSP29 precursor - Aspergillus
           niger
          Length = 299

 Score =  113 bits (273), Expect = 3e-24
 Identities = 60/140 (42%), Positives = 82/140 (58%), Gaps = 5/140 (3%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 471
           +NY YL+ D+ TKE+ I+DP  P  V   ++ Q     + L            AGGN ++
Sbjct: 58  NNYAYLVTDEPTKESVIIDPANPPEVAPTLKSQIDAGKIKLTSIVNTHHHWDHAGGNNEI 117

Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEG 648
           +K    L V GG +   ++TK   H   FKIG  ++V+ L TPCHT   ICYF+   ++G
Sbjct: 118 LKTFGQLSVIGGKN-CQSVTKTPAHGEVFKIGERISVKALHTPCHTQDSICYFM---QDG 173

Query: 649 NDSVVFTGDTLFLGGCGRFF 708
           +D VVFTGDTLF+GGCGRFF
Sbjct: 174 DDKVVFTGDTLFIGGCGRFF 193


>UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;
           Ascomycota|Rep: Hydroxyacylglutathione hydrolase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score =  113 bits (272), Expect = 4e-24
 Identities = 59/139 (42%), Positives = 81/139 (58%), Gaps = 4/139 (2%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG----VNLXXXXXXXXXXXXAGGNEDL 471
           +NY YL+    TK  AIVDP EP++V+  ++E+     ++L            AGGNED+
Sbjct: 16  NNYAYLLTCDKTKITAIVDPAEPESVIPVIKEKTAKKEIDLQYILTTHHHYDHAGGNEDI 75

Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651
           +   P L VYGG +  G +T   +    FK+G + V+ L TPCHT   ICY+V++P +  
Sbjct: 76  LSYFPSLKVYGGKNASG-VTYTPKDKEIFKVGEVQVEALHTPCHTQDSICYYVSSPSK-- 132

Query: 652 DSVVFTGDTLFLGGCGRFF 708
              VFTGDTLF  GCGRFF
Sbjct: 133 -RAVFTGDTLFTSGCGRFF 150


>UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Filobasidiella neoformans|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 274

 Score =  113 bits (271), Expect = 5e-24
 Identities = 60/146 (41%), Positives = 82/146 (56%), Gaps = 3/146 (2%)
 Frame = +1

Query: 280 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +K+LP  A  DN+MYLI+D ++ EAA+VDP +   +  AV+EQ  N+            +
Sbjct: 25  MKVLPYKARSDNWMYLIID-SSNEAAVVDPYDANKISGAVKEQRANVTSLITTHHHADHS 83

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHICYFV 630
           GGN   +   P L VY G  +       V+    F +G ++ V+CL TPCHT   IC+F+
Sbjct: 84  GGNSKFLSLHPNLKVYAGSTQSPGTNTVVKDGDTFTLGQDITVKCLHTPCHTQDSICFFL 143

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
              + G    VFTGDTLFL GCGRFF
Sbjct: 144 EDKKTGQRG-VFTGDTLFLAGCGRFF 168


>UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to
           myofibrillogenesis regulator 1; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to myofibrillogenesis
           regulator 1 - Monodelphis domestica
          Length = 286

 Score =  112 bits (270), Expect = 7e-24
 Identities = 58/156 (37%), Positives = 80/156 (51%), Gaps = 1/156 (0%)
 Frame = +1

Query: 235 EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414
           + HS+ +   +  + V  +P L DNY YLI+D  +K A  VDP +P+ V  A+E++GV L
Sbjct: 36  DGHSAVQPRVFNGVKVLPIPVLLDNYSYLIIDTQSKLAVAVDPSDPRAVQAAIEKEGVTL 95

Query: 415 XXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLF 591
                       +GGN +L +   G  VYG   D I  LT  + H     +G L  Q L 
Sbjct: 96  VAILCTHKHWDHSGGNRELRRHHRGCRVYGNPQDGIAHLTHPLCHQDMVSVGRLQFQALA 155

Query: 592 TPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           TP HT GH+ Y +        S +F+GD LFL GCG
Sbjct: 156 TPGHTRGHMVYVLDGEPYKGPSCLFSGDLLFLSGCG 191


>UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,
           partial; n=3; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 268

 Score =  112 bits (270), Expect = 7e-24
 Identities = 54/141 (38%), Positives = 80/141 (56%), Gaps = 1/141 (0%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +P L+DNY YL+++KA+  AA++DP + + V + +E+Q V L            +GGN+ 
Sbjct: 6   IPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQLTAILTTHKHWDHSGGNQK 65

Query: 469 LIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
           L      L VYGG+ D +     K++    F+IG L    LFTP HT GH+ Y +   ++
Sbjct: 66  LKSLHSNLAVYGGERDGVPGCNHKLKDGDSFQIGGLKFTALFTPGHTVGHMVYLLDRSDK 125

Query: 646 GNDSVVFTGDTLFLGGCGRFF 708
              + +FTGD LFLGG GR F
Sbjct: 126 NLPNSLFTGDILFLGGNGRMF 146


>UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep:
           Glyoxalase IIB - Plasmodium falciparum
          Length = 263

 Score =  112 bits (269), Expect = 9e-24
 Identities = 56/150 (37%), Positives = 83/150 (55%), Gaps = 7/150 (4%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459
           V ++P L DN+ Y+I+D+ TK+AA +DPVEP  VLK +E   V L            +GG
Sbjct: 7   VLVVPVLNDNFSYVIIDEKTKKAASIDPVEPDKVLKRIETANVELEYVLCTHHHYDHSGG 66

Query: 460 NEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636
           N  + + +  + V G   +    + +KV      ++G LN++ +  PCHT GHI Y+V  
Sbjct: 67  NIRMRELKQNIKVVGSAYEPTPGVNEKVYDGQIIRLGELNIKAIHAPCHTKGHILYYVYK 126

Query: 637 PEEGNDS------VVFTGDTLFLGGCGRFF 708
            +E          ++FTGDTLF+ GCGRFF
Sbjct: 127 TDEAKQEDHKYKPILFTGDTLFIAGCGRFF 156


>UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
           hydrolase - Dictyostelium discoideum AX4
          Length = 268

 Score =  109 bits (261), Expect = 9e-23
 Identities = 55/148 (37%), Positives = 81/148 (54%), Gaps = 5/148 (3%)
 Frame = +1

Query: 280 VKILPAL--QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEE--QGVNLXXXXXXXXXXX 447
           +K+ P L  +DNY YL++D+  K A  +DP EP  V+ ++      + +           
Sbjct: 1   MKVQPVLVNKDNYSYLVIDEKNKVAIAIDPCEPNKVISSLSSISSDIKINSVFTTHHHWD 60

Query: 448 XAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
            AGGN  +      + VYG D+R   +TKK+E+N   KIG+L ++ L  P HT+ H+ Y 
Sbjct: 61  HAGGNNLIKTIIKDINVYGRDERFEGITKKLENNEVLKIGSLKIKTLDAPAHTSSHVLYL 120

Query: 628 VTAPEEGND-SVVFTGDTLFLGGCGRFF 708
           +    E N    +FTGDTLF+GGCGR F
Sbjct: 121 IEDENEPNQVKSLFTGDTLFIGGCGRLF 148


>UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione
           hydrolase - Schizosaccharomyces pombe (Fission yeast)
          Length = 256

 Score =  109 bits (261), Expect = 9e-23
 Identities = 55/140 (39%), Positives = 82/140 (58%), Gaps = 4/140 (2%)
 Frame = +1

Query: 301 QDNYMYLIVDKATKEAAIVDPVEPKTVL----KAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           QDNY YL++ + T++AAIVDP E   V+    K ++ + ++L            +GGN +
Sbjct: 15  QDNYAYLLLCEETRQAAIVDPAEVNVVMPILKKKLKNKEIDLQAILTTHHHADHSGGNLN 74

Query: 469 LIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
           L KE P + +YGG D+ G ++  ++     +IGN+ ++ L TPCHT   IC++       
Sbjct: 75  LKKEFPHVTIYGGSDQNG-VSHVLQDKETLRIGNVQIEALHTPCHTRDSICFYA---HSS 130

Query: 649 NDSVVFTGDTLFLGGCGRFF 708
           N+  VFTGDTLF  GCGRFF
Sbjct: 131 NEHAVFTGDTLFNAGCGRFF 150


>UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 268

 Score =  107 bits (258), Expect = 2e-22
 Identities = 58/153 (37%), Positives = 79/153 (51%), Gaps = 5/153 (3%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGV---NLXXXXXXXXXX 444
           M +  +   +DNY Y++       A  VD  + + V  A E+ G+   N+          
Sbjct: 1   MKIHPVAVREDNYAYILQSSVDGRAVFVDVFDVEAVSGAAEKLGIPNENVVGLLTTHHHF 60

Query: 445 XXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFK--IGNLNVQCLFTPCHTTGHI 618
             +GGNE      PG  +YGG D+I ALTK V    +    +G ++++C+ TPCHT  HI
Sbjct: 61  DHSGGNEAFAHAYPGRPIYGGSDKIPALTKLVHDADRISELLGGVSIECVATPCHTQDHI 120

Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF*RH 717
           CY VT       S VFTGDTLF+ GCGRFF  H
Sbjct: 121 CYHVTDTTTA-QSGVFTGDTLFISGCGRFFEGH 152


>UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=13; Bacteria|Rep: Probable hydroxyacylglutathione
           hydrolase - Synechocystis sp. (strain PCC 6803)
          Length = 257

 Score =  103 bits (248), Expect = 3e-21
 Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           MD+  LPAL DNY++L+ D+   +AA+VDP E K VL  +E  G +L             
Sbjct: 1   MDIHRLPALADNYIFLLHDRQRNQAAVVDPAEAKPVLDCLETLGADLVTIYNTHHHGDHV 60

Query: 454 GGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624
           G N +L+ + P L VYGG     RI   T  +    +    +      F P HT GHI Y
Sbjct: 61  GANRELLAKYPNLEVYGGVEDQGRIPGQTVFLRDGDRLSFADREATVYFVPGHTRGHIAY 120

Query: 625 FVTAPEEGND-SVVFTGDTLFLGGCGRFF 708
           +  AP  G     +F GDT+F GGCGR F
Sbjct: 121 YF-APGSGETIGDLFCGDTIFAGGCGRLF 148


>UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase
           cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep:
           Hydroxyacylglutathione hydrolase cytoplasmic -
           Candidatus Pelagibacter ubique HTCC1002
          Length = 239

 Score =  101 bits (241), Expect = 2e-20
 Identities = 59/148 (39%), Positives = 82/148 (55%), Gaps = 3/148 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M+++I+  LQDNY YLIVDKA   A ++DP E K V+K +E++ ++L             
Sbjct: 1   MEIQIIRCLQDNYSYLIVDKAKNIACVIDPSEAKPVIKYLEDKNIHLKYILNTHHHYDHV 60

Query: 454 GGNEDLIKERPG--LIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624
           GGN++L KE+ G  +I Y GD DRI  +   V     +   N   +    P HT GHIC+
Sbjct: 61  GGNKEL-KEKYGASVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICF 119

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +       N+  VFTGDTLF  GCG+ F
Sbjct: 120 YFY-----NEESVFTGDTLFSLGCGKIF 142


>UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 659

 Score = 95.9 bits (228), Expect = 9e-19
 Identities = 54/135 (40%), Positives = 76/135 (56%), Gaps = 5/135 (3%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 471
           +NY YL+ D+ TK++ I+DP  P  V+  +E Q     +NL            AGGN ++
Sbjct: 394 NNYAYLVTDEPTKQSVIIDPANPPEVVPELEAQTKAGKINLTAIVNTHHHWDHAGGNNEV 453

Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEG 648
           +K    + V GG D   ++TK   H   FKIG+ ++V  L TPCHT   ICYF+   ++G
Sbjct: 454 LKTFK-VPVIGGKD-CQSVTKTPAHGEVFKIGDRISVTALHTPCHTQDSICYFM---QDG 508

Query: 649 NDSVVFTGDTLFLGG 693
               VFTGDTLF+GG
Sbjct: 509 EQKAVFTGDTLFIGG 523


>UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=2; Theileria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Theileria annulata
          Length = 362

 Score = 74.5 bits (175), Expect(2) = 1e-18
 Identities = 36/87 (41%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
 Frame = +1

Query: 454 GGNEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GGN  + K  P + V G   +    +T  V+H      GNL ++CL   CHT GHI Y+V
Sbjct: 170 GGNNGIKKLVPDVEVVGSSYEETPGVTLPVKHEQTLTFGNLVIKCLKASCHTLGHIMYYV 229

Query: 631 TAPEEGNDS-VVFTGDTLFLGGCGRFF 708
             P   +   ++F+GDTLF+ GCGRFF
Sbjct: 230 YHPSNDHQQPLLFSGDTLFISGCGRFF 256



 Score = 41.5 bits (93), Expect(2) = 1e-18
 Identities = 19/46 (41%), Positives = 27/46 (58%)
 Frame = +1

Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414
           +V I+P LQDNY Y++ D  +  A  VDPVE + V    +E  + L
Sbjct: 85  EVLIVPVLQDNYSYVLKDPESSNALCVDPVEYEKVYNVCKENDLEL 130


>UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 318

 Score = 92.7 bits (220), Expect = 8e-18
 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 6/164 (3%)
 Frame = +1

Query: 235 EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414
           E HS      ++ + +  +P L DNY Y+IVD  T  A +VDP +P+ V   + ++ + L
Sbjct: 38  EPHSIALPWIHEGLKIIPVPFLYDNYSYIIVDITTSSAVVVDPSDPEAVKDVLNKEKLQL 97

Query: 415 XXXXXXXXXXXXAGGNEDLIKERPGLIVYGG--DDRIGAL-TKKV---EHNTKFKIGNLN 576
                       +GGN  L  + P + VYG   DD  G   T+K      N   K+  L+
Sbjct: 98  EAVLTTHKHWDHSGGNTSLKADFPSVAVYGSELDDAPGLTHTRKPLCDISNFSGKVSQLS 157

Query: 577 VQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
                TP HT GH+ Y +      +   +F+GD LFLGGCGR F
Sbjct: 158 FTAFSTPGHTAGHVVYLLHGAVFNSVDSLFSGDLLFLGGCGRIF 201


>UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=8; Trypanosomatidae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Leishmania
           major
          Length = 295

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 59/161 (36%), Positives = 82/161 (50%), Gaps = 18/161 (11%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDP-VEPKTVLKAVEE----QG-----VNLXXXXX 429
           V ++P L+DN+ YLI D  T   A VD   + K +L  +EE    QG             
Sbjct: 15  VTVVPTLKDNFSYLINDHTTHTLAAVDVNADYKPILTYIEEHLKQQGNADVTYTFSTILS 74

Query: 430 XXXXXXXAGGNEDLIKER-------PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCL 588
                  +GGN  L  E        P ++V G +D I A+TK V    + ++GNL+V+ +
Sbjct: 75  THKHWDHSGGNAKLKAELEAMNSMVPVMVVGGANDGIPAVTKPVREGDRVQVGNLSVEVI 134

Query: 589 FTPCHTTGHICYFVTAPEEGNDSV-VFTGDTLFLGGCGRFF 708
             PCHT GH+ Y V  P+  ND V +FTGDT+F+ G G FF
Sbjct: 135 DAPCHTRGHVLYKVQHPQHPNDGVALFTGDTMFIAGIGAFF 175


>UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase
           - Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 282

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 54/154 (35%), Positives = 79/154 (51%), Gaps = 6/154 (3%)
 Frame = +1

Query: 265 YKNMDVKILP---ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG--VNLXXXXX 429
           Y+ M +  +P      DNY YL+VD  +K A ++DP  P  V + ++E+     L     
Sbjct: 25  YRKMHILPIPMRWGQGDNYAYLLVDDRSKNAWLIDPAVPLEVNEFIKEKKPKYELKAIVN 84

Query: 430 XXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHT 606
                  + GN++  ++ P L +  G D    +T    H     +G+ L+V  L TPCHT
Sbjct: 85  THHHYDHSDGNKEFHRKYPDLPIIAGKDS-PLVTYTPSHEEVIDLGDDLSVTALHTPCHT 143

Query: 607 TGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
              ICY+V   + G +  VFTGDTLF+ GCGRFF
Sbjct: 144 QDSICYYVKDAKTG-EKAVFTGDTLFISGCGRFF 176


>UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep:
           All0580 protein - Anabaena sp. (strain PCC 7120)
          Length = 257

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 51/148 (34%), Positives = 72/148 (48%), Gaps = 3/148 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M V  L AL DNY++L+ D     AA+VDP E + VLK + +    L             
Sbjct: 1   MQVIRLAALSDNYIFLLHDSHKNIAAVVDPAEAEPVLKQLAQLKAELVAIFNTHHHNDHV 60

Query: 454 GGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624
           GGN+ LI++ P + VYGG     RI      ++   + +  +   + +F P HT  HI Y
Sbjct: 61  GGNQKLIQKFPQVKVYGGAKDQGRIPGQQVFLQPGDRVQFADRVAEVIFVPGHTRAHIAY 120

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +     +     +F GDTLF GGCGR F
Sbjct: 121 YFPPQTDDTPGELFCGDTLFAGGCGRLF 148


>UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 722

 Score = 89.8 bits (213), Expect = 6e-17
 Identities = 56/136 (41%), Positives = 71/136 (52%), Gaps = 1/136 (0%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           DNY YL+VD  +KEA ++DP  P                          AGGNE+L+ E 
Sbjct: 491 DNYAYLVVDDKSKEAVVIDPAHPAD--------------------HWDHAGGNEELLSEL 530

Query: 484 -PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
              L + GG D    +TK   H   F IG++ V+ L TPCHT   IC+F+   ++GND V
Sbjct: 531 GQPLEIIGGKD-CKKVTKTPPHGATFNIGDIAVKALHTPCHTQDSICFFM---QDGNDKV 586

Query: 661 VFTGDTLFLGGCGRFF 708
           VFTGDTLF GG   FF
Sbjct: 587 VFTGDTLFHGGEFLFF 602


>UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 280

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 43/129 (33%), Positives = 70/129 (54%), Gaps = 1/129 (0%)
 Frame = +1

Query: 235 EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414
           + HS  E  + + + +  +P L+DNY YL+++KA+  AA++DP + + V + +E+Q V L
Sbjct: 29  DGHSVVEHTEVEGVIILPIPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQL 88

Query: 415 XXXXXXXXXXXXAGGNEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLF 591
                       +GGN+ L      L VYGG+ D +    +K++    F+IG L    LF
Sbjct: 89  TAILTTHKHWDHSGGNQTLKSLHSNLAVYGGERDGVPGCNRKLKDGDSFQIGGLKFTALF 148

Query: 592 TPCHTTGHI 618
           TP HT G +
Sbjct: 149 TPGHTVGRM 157


>UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep:
           HAGHL protein - Homo sapiens (Human)
          Length = 203

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 39/97 (40%), Positives = 61/97 (62%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M VK++P L+DNYMYL++++ T+EA  VD   PK +L+ V  +GV+L            A
Sbjct: 1   MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKI 564
            GN +L + RPGL V G D+RI +LT+++ H  + ++
Sbjct: 61  RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRV 97


>UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase,
           mitochondrial precursor; n=10; Saccharomycetales|Rep:
           Hydroxyacylglutathione hydrolase, mitochondrial
           precursor - Saccharomyces cerevisiae (Baker's yeast)
          Length = 285

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 48/141 (34%), Positives = 74/141 (52%), Gaps = 7/141 (4%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVL-KAVEEQGVNLXXXXXXXXXXXXAGGN----EDL 471
           NY YL+  +  + + ++DP EP  V  K   E+  ++            +GGN      L
Sbjct: 26  NYSYLLSTEDRRNSWLIDPAEPLEVSPKLSAEEKKSIDAIVNTHHHYDHSGGNLALYSIL 85

Query: 472 IKERPG--LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
            +E  G  + + GG      +T+  ++  ++ +GNL V C+ TPCHT   ICY++   E 
Sbjct: 86  CQENSGHDIKIIGGSKSSPGVTEVPDNLQQYHLGNLRVTCIRTPCHTKDSICYYIKDLET 145

Query: 646 GNDSVVFTGDTLFLGGCGRFF 708
           G +  +FTGDTLF+ GCGRFF
Sbjct: 146 G-EQCIFTGDTLFIAGCGRFF 165


>UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=4; Legionella pneumophila|Rep: Hydroxyacylglutathione
           hydrolase GloB - Legionella pneumophila (strain Corby)
          Length = 254

 Score = 86.2 bits (204), Expect = 7e-16
 Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M +  + A  DNY++  +DK       VDP E   +++  +   + L             
Sbjct: 1   MTILPISAFSDNYIWAFIDKIAGVLDCVDPGEAAPIIRFAQSNQLTLRTILLTHHHYDHI 60

Query: 454 GGNEDLIKERPGLIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG + LIK+ P   VYG  D+RI  +T  ++     ++G+L+   LF P HT+ HI Y+ 
Sbjct: 61  GGVDSLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYY- 119

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
             P++G    +F GDTLF  GCGR F
Sbjct: 120 -EPQKG---WLFCGDTLFSAGCGRVF 141


>UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Acinetobacter sp. ADP1|Rep: Putative
           hydroxyacylglutathione hydrolase - Acinetobacter sp.
           (strain ADP1)
          Length = 244

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 50/137 (36%), Positives = 72/137 (52%), Gaps = 3/137 (2%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           NY++++ D  T+E  +VDP E   V +  E+  V +             GG  DLI +  
Sbjct: 17  NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLI-DGS 75

Query: 487 GLIVYGGDD---RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657
            + VYG  +   +I  +T  ++H   FK  +LNV+ L TP HT GH+ YF+   E G+  
Sbjct: 76  HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFI--EETGS-- 131

Query: 658 VVFTGDTLFLGGCGRFF 708
            +F GDTLF  GCGR F
Sbjct: 132 -LFCGDTLFAMGCGRVF 147


>UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep:
           Hydroxyacylglutathione hydrolase - Mariprofundus
           ferrooxydans PV-1
          Length = 262

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 50/152 (32%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
 Frame = +1

Query: 259 HQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXX 438
           + + N  V  LP L+DNY+YLI   A+    ++DP E  +V +A  E G  L        
Sbjct: 4   YNHSNFTVHQLPVLKDNYIYLIEAHASSALIVIDPAEAVSVRRACRELGKPLTHIFNTHH 63

Query: 439 XXXXAGGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTG 612
                 GN+ L K+   +++    D  RI  +  KV   +   +  LN++ L    HT G
Sbjct: 64  HWDHTDGNQSLKKDFGAVVIGAAHDAERIPGINLKVSEASPPLVDGLNIRVLDVAGHTRG 123

Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           HI Y +       D  +F GDTLF  GCGR F
Sbjct: 124 HIAYLL-------DDALFCGDTLFGAGCGRLF 148


>UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep:
           Glyoxalase II - Oryza sativa (Rice)
          Length = 336

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 49/149 (32%), Positives = 73/149 (48%), Gaps = 3/149 (2%)
 Frame = +1

Query: 271 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450
           ++ ++++P LQDNY Y++ D  T    +VDP E   ++ A+E++  NL            
Sbjct: 82  SLQIELVPCLQDNYAYILHDVDTGTVGVVDPSEATPIINALEKRNQNLTYILNTHHHYDH 141

Query: 451 AGGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621
            GGN +L K + G  V G     DRI  +   +     +      V  + TP HT+GH+C
Sbjct: 142 TGGNLEL-KAKYGAKVIGSAKDRDRIPGIDITLSEGDTWMFAGHQVLVMETPGHTSGHVC 200

Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           Y    P  G    +FTGDTLF   CG+ F
Sbjct: 201 YHF--PGSG---AIFTGDTLFSLSCGKLF 224


>UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein;
           n=1; Limnobacter sp. MED105|Rep: Metallo-beta-lactamase
           family protein - Limnobacter sp. MED105
          Length = 257

 Score = 83.0 bits (196), Expect = 7e-15
 Identities = 52/158 (32%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
 Frame = +1

Query: 247 SQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXX 426
           S +  Q  N  V  +PA QDNY++ IV + +K   +VDP   K+V + ++  G +L    
Sbjct: 3   SFKSSQVSNWSVYGIPAFQDNYLWAIVHEPSKACMVVDPGCSKSVQEFLDSHGYHLSGIL 62

Query: 427 XXXXXXXXAGGNEDLI-KERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPC 600
                    GG + L+ K    L VYG    RI  + + V       +  L  Q L  P 
Sbjct: 63  VTHHHMDHVGGIDALLSKAGKDLPVYGPASGRIAQINRPVREGDTVDVHCLVAQVLEVPG 122

Query: 601 HTTGHICYFVTAPEEGN--DSVVFTGDTLFLGGCGRFF 708
           HT  H+ Y +   +  N  ++ +F GDTLF GGCGR F
Sbjct: 123 HTVDHLAYVIELKDTMNSEETWMFPGDTLFSGGCGRLF 160


>UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=7; Prochlorococcus marinus|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Prochlorococcus marinus
          Length = 253

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 48/144 (33%), Positives = 72/144 (50%), Gaps = 4/144 (2%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +P L DN +++ V +  K+A +VDP   + V+  ++  G++L             GG ++
Sbjct: 13  IPVLMDNIIWIWVKE--KQAIVVDPAISEPVINLLKGNGLSLHSVLQTHHHEDHIGGTQE 70

Query: 469 LIKERPGLIVYGGD---DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAP 639
           LI   P   V       DRI   TK V  N +  I    ++ +  P HT+ HIC+F+   
Sbjct: 71  LINVWPSASVIAAKSDLDRIQFQTKSVVDNEELDILGQKIKVIEVPGHTSNHICFFLQGS 130

Query: 640 EEGN-DSVVFTGDTLFLGGCGRFF 708
           +E   D V+F GDTLF  GCGR F
Sbjct: 131 KESKIDPVLFCGDTLFGAGCGRLF 154


>UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein;
           n=9; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Methylococcus capsulatus
          Length = 256

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 48/148 (32%), Positives = 78/148 (52%), Gaps = 3/148 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++  +P L+DNY+YL+ +  +   A VDP     VL+A++ +G  L             
Sbjct: 2   LEILQIPVLEDNYVYLLHEPGSGATAAVDPAVAGPVLEALDARGWRLGHVLNTHHHGDHV 61

Query: 454 GGNEDLIKERPGLIVYG--GD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624
           GGN +L K   G  V G  GD  RI  +   ++   +F++G+ + + L  P HT+GH+ +
Sbjct: 62  GGNLEL-KAATGCTVVGAAGDRHRIPGIDVALKDGEEFRLGSASARMLDVPGHTSGHVAF 120

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +       +D+ +F GDTLF  GCGR F
Sbjct: 121 WFE-----DDAALFCGDTLFALGCGRLF 143


>UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=40; Gammaproteobacteria|Rep: Probable
           hydroxyacylglutathione hydrolase - Escherichia coli
           O157:H7
          Length = 251

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 49/147 (33%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M++  +PA  DNY++++ D+A +   IVDP + + VL A+                    
Sbjct: 1   MNLNSIPAFDDNYIWVLNDEAGR-CLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHV 59

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKV--EHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
           GG ++L+++ P ++VYG  +     T +V  +  T F +G+     + TP HT GHICYF
Sbjct: 60  GGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGH-EFSVIATPGHTLGHICYF 118

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
                  +   +F GDTLF GGCGR F
Sbjct: 119 -------SKPYLFCGDTLFSGGCGRLF 138


>UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=7; Bacteria|Rep: Metallo-beta-lactamase
           superfamily protein - marine gamma proteobacterium
           HTCC2143
          Length = 260

 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 49/144 (34%), Positives = 73/144 (50%), Gaps = 1/144 (0%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459
           ++ +PA  DNY++ I D  + +AA+VDP E   V +A+  Q + L             GG
Sbjct: 4   IEPIPAFNDNYIWCIYDDDSGKAAVVDPGEAGPVEEALLAQQLQLETILITHHHFDHTGG 63

Query: 460 NEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636
            E L K R  + VYG  + +I ++T +++  +   +  L+   L  P HT  HI  +   
Sbjct: 64  IEALTKHR-DIPVYGPKNHQIASITHRLDEQSSMSLFGLDFTILEVPGHTLDHIALYCED 122

Query: 637 PEEGNDSVVFTGDTLFLGGCGRFF 708
              G   V+F GDTLF GGCGR F
Sbjct: 123 TGTG-QPVLFCGDTLFAGGCGRIF 145


>UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including
           glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent
           hydrolase, including glyoxylase - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 270

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 49/146 (33%), Positives = 70/146 (47%), Gaps = 3/146 (2%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459
           V+ +P L DNY+YL  +      A +DP   + VL+ +  +G  L             G 
Sbjct: 19  VEQIPVLSDNYVYLAHEPLGGATAAIDPAVSEPVLERLAARGWTLTHILNTHHHGDHTGA 78

Query: 460 NEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           N DL + R G  V G     +RI  +T +V     F +G+  V  L  P HT+GH+ Y++
Sbjct: 79  NLDLAR-RTGCAVVGAARDSERIPGITLEVSEGETFMLGHAAVTVLEVPGHTSGHVAYWL 137

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
                 +  V+F GDTLF  GCGR F
Sbjct: 138 -----ADSHVLFCGDTLFSLGCGRLF 158


>UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Desulfuromonas acetoxidans DSM 684|Rep:
           Hydroxyacylglutathione hydrolase - Desulfuromonas
           acetoxidans DSM 684
          Length = 249

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 50/145 (34%), Positives = 73/145 (50%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++ +L A  DNY Y+I D  T  A  +DP E + VL  +E+ G +L             
Sbjct: 2   VEITLLQAHDDNYAYMISDGDTTIA--IDPGEAEPVLDYLEKHGRSLSLILNTHMHQDHC 59

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           GGN  L K   G  + GGD+RI  + + ++ ++        +Q + TP HT G  CY++ 
Sbjct: 60  GGNLTL-KRLTGCHIAGGDERIVGVDRLLQEDSVLPGLPWPLQVMHTPGHTRGDCCYYLP 118

Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708
             E      +F GDTLF GGCGR F
Sbjct: 119 QCE-----ALFCGDTLFSGGCGRVF 138


>UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione
           hydrolase-like isoform 2; n=1; Pan troglodytes|Rep:
           PREDICTED: hydroxyacylglutathione hydrolase-like isoform
           2 - Pan troglodytes
          Length = 285

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 46/142 (32%), Positives = 69/142 (48%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M VK++P L+DNYMYL++++ T+EA  VD   PK V      QG                
Sbjct: 1   MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRVRAGRGPQGPGRVPREPPRPLWQER 60

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
                 +++    +  GG     ALT       +F  G ++V+CL TP HT GH+ YF+ 
Sbjct: 61  SPTCSALRKS---LAAGGAPGPPALTGPPAPPPQF--GAIHVRCLLTPGHTGGHMSYFLW 115

Query: 634 APEEGNDSVVFTGDTLFLGGCG 699
             +  +   +F+GD L + GCG
Sbjct: 116 EDDCPDPPALFSGDALSVAGCG 137


>UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase
           with metallo- hydrolase/oxidoreductase domain; n=4;
           Proteobacteria|Rep: Putative hydroxyacylglutathione
           hydrolase with metallo- hydrolase/oxidoreductase domain
           - Pseudoalteromonas tunicata D2
          Length = 261

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 3/148 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           + VK + A +DNY++ I++   +   +VDP + + V+  + E  + L             
Sbjct: 4   LQVKPIKAFKDNYIWAIINTENQHCVVVDPGDAEPVIAFISEHQLTLSAILITHHHWDHT 63

Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIG--NLNVQCLFTPCHTTGHICY 624
            G E L   +  L VYG  +     +T+ +  NT  ++   +L+   L TP HT  HICY
Sbjct: 64  NGVEKLCSLQASLPVYGPKNSPFAGITEPLSANTVCQLTDFDLSFHILATPGHTLDHICY 123

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +     E     +F GDTLF GGCGR F
Sbjct: 124 Y-----EPQQDWLFCGDTLFSGGCGRLF 146


>UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep:
           Glyoxylase - Ostreococcus tauri
          Length = 512

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 49/158 (31%), Positives = 70/158 (44%), Gaps = 18/158 (11%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +P + DNY YL+VD  T+EA  +DP +P+  + A    G  L            AGGN  
Sbjct: 149 IPFMNDNYSYLVVDADTREACAIDPADPERAVDAARRCGAKLTTVLTTHKHHDHAGGNAR 208

Query: 469 ----LIKERPGLI---VYG-GDDRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHIC 621
               +  E  G +   VYG   D+    T++V+     ++G  L    +  PCHT GH+ 
Sbjct: 209 VRAMMALEENGSVDVEVYGHAMDKCHGTTREVKDGDVVRVGARLRFLVIHVPCHTLGHVV 268

Query: 622 YFVTAPEE---------GNDSVVFTGDTLFLGGCGRFF 708
           Y +   E           N   +FTGD +  GG G FF
Sbjct: 269 YALLGDEREDGADGPTLANAKAMFTGDAIINGGVGAFF 306


>UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas mendocina ymp
          Length = 257

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG-VNLXXXXXXXXXXXX 450
           + +  LPA  DNY++L+ D  ++  A+VDP +   VL  +E  G   L            
Sbjct: 2   IQIDALPAFNDNYIWLLQDPISRRCAVVDPGDAAPVLAWLEAHGDWTLSDILITHHHFDH 61

Query: 451 AGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
            GG E L K     +     ++I A    +  N   ++  L  Q +  P HT GHI Y+ 
Sbjct: 62  VGGVEQLKKATGARVAGPAAEKIPARDVDLGDNDLIEVLGLRFQIMAVPGHTLGHIAYY- 120

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
                   +++  GDTLF GGCGR F
Sbjct: 121 ----HAEQNLLLCGDTLFAGGCGRLF 142


>UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1,
           mitochondrial precursor; n=12; core eudicotyledons|Rep:
           Hydroxyacylglutathione hydrolase 1, mitochondrial
           precursor - Arabidopsis thaliana (Mouse-ear cress)
          Length = 331

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 45/146 (30%), Positives = 72/146 (49%), Gaps = 3/146 (2%)
 Frame = +1

Query: 271 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450
           ++ ++++P  +DNY YL+ D+ T    +VDP E   V++A+  +  NL            
Sbjct: 77  SLKIELVPCSKDNYAYLLHDEDTGTVGVVDPSEAAPVIEALSRKNWNLTYILNTHHHDDH 136

Query: 451 AGGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621
            GGN +L KER G  V G     DRI  +   ++ + K+      V+ L TP HT GHI 
Sbjct: 137 IGGNAEL-KERYGAKVIGSAVDKDRIPGIDILLKDSDKWMFAGHEVRILDTPGHTQGHIS 195

Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCG 699
           ++         + +FTGD ++   CG
Sbjct: 196 FYFP-----GSATIFTGDLIYSLSCG 216


>UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Pseudomonas stutzeri (strain A1501)
          Length = 292

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE-EQGVNLXXXXXXXXXXXXAG 456
           ++ LPA  DNY++L+ D A +    VDP +   VL  +    G  L             G
Sbjct: 37  IEALPAFTDNYIWLLQDDAARRCVAVDPGDAAPVLNWLSAHPGWQLSDILVTHHHHDHVG 96

Query: 457 GNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           G E L K + G  VYG   ++I A  + +    + ++    +Q +  P HT GHI YF  
Sbjct: 97  GVERL-KAQTGARVYGPAAEKIPARDEALSDGQRIEVLGKRLQIIAVPGHTLGHIAYFHA 155

Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708
            P++     + +GDTLF  GCGR F
Sbjct: 156 DPDQ---PWLLSGDTLFAAGCGRLF 177


>UniRef50_UPI0000DAE586 Cluster: hypothetical protein
           Rgryl_01000658; n=1; Rickettsiella grylli|Rep:
           hypothetical protein Rgryl_01000658 - Rickettsiella
           grylli
          Length = 257

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 3/148 (2%)
 Frame = +1

Query: 274 MDVKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447
           M +++LP  A +DNY++ ++++ TK   IVDP E K VL  +++  + L           
Sbjct: 1   MTIQLLPILAFKDNYIWCLINEETKHCLIVDPGEAKPVLAQLKQLNLTLDALLITHHHWD 60

Query: 448 XAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNL-NVQCLFTPCHTTGHICY 624
              G   ++   P  +     ++I  +T  V    K ++ +  + + L  P HT GHI Y
Sbjct: 61  HTNGIRSILNHYPVPVFGPSKEKIVGVTHPVNETDKIELTHWPSFEILAIPGHTLGHIAY 120

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +      GN  ++F GDTLF  GCGR F
Sbjct: 121 Y------GN-HLLFCGDTLFTAGCGRLF 141


>UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; cellular organisms|Rep:
           Hydroxyacylglutathione hydrolase, putative - Caulobacter
           crescentus (Caulobacter vibrioides)
          Length = 249

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 44/139 (31%), Positives = 68/139 (48%), Gaps = 2/139 (1%)
 Frame = +1

Query: 298 LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIK 477
           L DNY +L+ D+A+ + A +D  +   +L  + + G +L            AGGNE L K
Sbjct: 11  LSDNYGFLVRDEASGKVATIDTPDAGAILAELAKLGWSLDLILNTHWHPDHAGGNETL-K 69

Query: 478 ERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651
              G  + G  +  RI  L + V    +  +G+  +  + T  HT GH+ Y+     +  
Sbjct: 70  TATGATIVGPAEVTRIAPLDRVVRDGEEVMLGDTRLTVIDTGGHTLGHVSYY-----DAE 124

Query: 652 DSVVFTGDTLFLGGCGRFF 708
           D++ F GDTLF  GCGR F
Sbjct: 125 DAIAFVGDTLFALGCGRLF 143


>UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Marinomonas|Rep: Hydroxyacylglutathione hydrolase -
           Marinomonas sp. MWYL1
          Length = 257

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 45/143 (31%), Positives = 64/143 (44%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M +  LPA  DNY+++I DK +     VDP +   VL    E    L             
Sbjct: 1   MTIFPLPAFNDNYIWIIQDKDSSGIWAVDPGKADVVLNFCHEYQKTLTGILITHHHKDHT 60

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           GG  +L K+     VYG +     +T  V+   +  + +     + TP HT  H+CYF  
Sbjct: 61  GGVAEL-KQHSNCPVYGPEHLTELVTHPVDDGDRILVFSKVFTVIATPGHTLDHLCYF-- 117

Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702
              E    ++ +GDTLF GGCGR
Sbjct: 118 --SEQETPILLSGDTLFKGGCGR 138


>UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily
           protein; n=6; Bacteroidetes|Rep: Metallo-beta-lactamase
           superfamily protein - Porphyromonas gingivalis
           (Bacteroides gingivalis)
          Length = 471

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 43/121 (35%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
 Frame = +1

Query: 343 EAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519
           EAAI+DP+   T  L+ ++  GV L              G+ DL +     IVYG   + 
Sbjct: 23  EAAIIDPLREITPYLERLKRDGVKLKYILETHFHADFVSGHLDLSRATGAPIVYGPTAKP 82

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           G      E N  F++GN+ ++ L TP HT    C F+   E G ++ +F+GDTLFLG  G
Sbjct: 83  GFDAIVAEDNQIFELGNVKIRVLHTPGHTMESSC-FLLIDENGREAALFSGDTLFLGDVG 141

Query: 700 R 702
           R
Sbjct: 142 R 142


>UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase
           (Glyoxalase II) (GLX II) protein; n=1; alpha
           proteobacterium HTCC2255|Rep: Putative
           hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX
           II) protein - alpha proteobacterium HTCC2255
          Length = 255

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 49/148 (33%), Positives = 64/148 (43%), Gaps = 2/148 (1%)
 Frame = +1

Query: 271 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450
           ++ V I+P L DNY YLI  + T   A++D  +   +L  + E G  L            
Sbjct: 2   SLSVIIVPCLIDNYAYLIRCEETGHTAVIDVPDAYPILNMINELGWKLNSILITHHHSDH 61

Query: 451 AGGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624
             G E L K     ++    D  R+  L   V       IGN   + L TP HT GHI Y
Sbjct: 62  VDGVEQLQKLTGANVIGAKSDSHRLPNLNISVSTGDVISIGNQQAEILNTPGHTIGHISY 121

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           F       +   VFTGD+L   GCGR F
Sbjct: 122 FFK-----DSKKVFTGDSLMSLGCGRLF 144


>UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Psychromonas|Rep: Hydroxyacylglutathione hydrolase -
           Psychromonas ingrahamii (strain 37)
          Length = 256

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 46/146 (31%), Positives = 70/146 (47%), Gaps = 2/146 (1%)
 Frame = +1

Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           +V  + A +DNY++LI D  ++   IVDP +   VL  +E+Q + +             G
Sbjct: 3   NVITIKAFEDNYIWLIKDSQSQHCIIVDPGDAAPVLTILEDQKLIVDAILLTHHHYDHIG 62

Query: 457 GNEDLIKERPGLI-VYGGDDRIGALTKKVEHNT-KFKIGNLNVQCLFTPCHTTGHICYFV 630
           G + L+  R   I +Y             E +T  F  G L++Q +  P HT  H+ ++ 
Sbjct: 63  GVDALLSARDEKISIYSKKKLFDRCRLVNESDTLSFFDGKLSLQVMEVPGHTLDHVAFY- 121

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
                 ND ++F GDTLF GGCGR F
Sbjct: 122 ------NDELLFCGDTLFSGGCGRVF 141


>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
           Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
           japonicum
          Length = 255

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 48/147 (32%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
 Frame = +1

Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           +++    L DN+ YLI D  TK  A +D  E   +LKA+E +G  L             G
Sbjct: 4   EIRTFSCLNDNFGYLIHDVETKATASIDAPEAGPILKALEREGWQLTDILITHHHGDHVG 63

Query: 457 GNEDLIKERPGLIVYGGDDRIGALTK---KVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
           G  +L K +    V    D+  A+     +V +    K+GNL  + + TP HT  HI Y 
Sbjct: 64  GVAEL-KHKYNCRVVAPHDKTTAIANVDLRVANADVVKVGNLLARVVETPGHTLDHISYV 122

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
                   +  VF  DTLF  GCGR F
Sbjct: 123 F-----DTEKTVFAADTLFSIGCGRVF 144


>UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Marinobacter|Rep: Hydroxyacylglutathione hydrolase -
           Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 263

 Score = 70.5 bits (165), Expect = 4e-11
 Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M +  +PA  DNY++ + +  + +  IVDP + K VL  + + G +              
Sbjct: 1   MRIHPVPAFSDNYIWCLTNLESGKTLIVDPGQAKPVLDYLSDSGFSADTILITHHHPDHT 60

Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG ++L ++ P L + G  D      T  V    +     +    L  P HT  HI Y+ 
Sbjct: 61  GGVKELQQQYPDLRIVGPTDSPFKGATNTVHAGDEVVWEGITFNVLAVPGHTLDHIAYY- 119

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +  +  +  V+F GDTLF+ GCGR F
Sbjct: 120 SDTQVNDKPVLFCGDTLFVCGCGRLF 145


>UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein;
           n=2; Alteromonadales|Rep: Metallo-beta-lactamase family
           protein - Colwellia psychrerythraea (strain 34H / ATCC
           BAA-681) (Vibriopsychroerythus)
          Length = 265

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459
           V  + A  DNY++ I  +   + A+VDP +    +K ++E  + L             GG
Sbjct: 8   VTAINAFNDNYIWAISSQNNDKIALVDPGDAVVCIKYLQENNLALSAILITHHHSDHVGG 67

Query: 460 NEDLI---KERPGLI-VYG-GDDRIGALTKKVEHNTKFKIGNLNVQ--CLFTPCHTTGHI 618
            E L+   K++   + VYG   ++I  L   ++ N    +  L+ Q   L  P HT GHI
Sbjct: 68  IEKLLEYSKDKAWPVTVYGPATEKIAQLDITLKENDTVDLTELDCQFTVLDLPGHTKGHI 127

Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
            Y+       ND +VF GDTLF GGCGR F
Sbjct: 128 AYY-------NDKMVFCGDTLFSGGCGRLF 150


>UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;
           Proteobacteria|Rep: Hydroxyacylglutathione hydrolase -
           Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 268

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 49/146 (33%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +PA  DNY++L+ D   ++A  VDP E   V + + E+G  L             GG   
Sbjct: 9   VPAFDDNYIWLVSDG--RDAIAVDPGEAAPVRRVLAERGWRLTAILLTHHHADHVGGVAA 66

Query: 469 LIKERPG---LIVYG-GDDRIGALTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHICYFV 630
           L   +P    L VYG   + IG +T+ +    +  +         L  P HT GHI YF 
Sbjct: 67  LRDSQPDDAPLTVYGPAAEAIGVVTRPLSGGDRVTLDAPAATFDVLDVPGHTRGHIAYFQ 126

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
            A +      VF GDTLF  GCGR F
Sbjct: 127 AAGQGNAAPHVFCGDTLFSCGCGRLF 152


>UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including
           glyoxylases; n=1; Hahella chejuensis KCTC 2396|Rep:
           Zn-dependent Hydrolase, including glyoxylases - Hahella
           chejuensis (strain KCTC 2396)
          Length = 257

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 1/141 (0%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +PA  DNY++ I      +A +VDP + + VL+ + E  + L             GG  +
Sbjct: 7   IPAFNDNYIWSI-QSDQGDAWVVDPGDAQPVLRHLAENHLTLRGILITHHHHDHTGGVNE 65

Query: 469 LIKERPGLIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
           L+   P + VYG     I A+T  ++   +  +G+ +++ L TP HT  HI YF    + 
Sbjct: 66  LLANHP-VPVYGFMRSAIKAITVPLQEGDRVDLGDFSLEVLETPGHTLDHISYF---GDI 121

Query: 646 GNDSVVFTGDTLFLGGCGRFF 708
                +F GDTLF  GCGR F
Sbjct: 122 AGAPRLFCGDTLFSAGCGRLF 142


>UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Neptuniibacter caesariensis|Rep:
           Metallo-beta-lactamase superfamily protein -
           Neptuniibacter caesariensis
          Length = 257

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 45/141 (31%), Positives = 64/141 (45%), Gaps = 1/141 (0%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +PA  DNY+++I    +   A+VDP +   VL  +EE  + L             GG E 
Sbjct: 7   IPAFSDNYIWVIASPDSNMVAVVDPGDEAPVLAYLEENNLQLTAILITHHHNDHTGGVEA 66

Query: 469 LIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
           L K+R    VYG  +     +T  +      ++   +V     P HT  HI Y+     E
Sbjct: 67  L-KDRFKTPVYGPANSPFQGITHPLNDGDSIQLMGASVAIKAIPGHTLDHISYY----SE 121

Query: 646 GNDSVVFTGDTLFLGGCGRFF 708
            +   +F GDTLFL GCGR F
Sbjct: 122 RHKPQLFCGDTLFLAGCGRLF 142


>UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=4; Proteobacteria|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Verminephrobacter eiseniae (strain EF01-2)
          Length = 258

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 44/146 (30%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M++  LPA  DNY++++ D     A +VDP +   V  A+   G+ L             
Sbjct: 1   MNLLALPAFADNYLWMLHDG--HRAIVVDPGQAAPVADALRRLGLQLQAILVTHHHADHV 58

Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG E L +   G  V+G   + +     ++       +  L ++ +  P HT GHI Y+ 
Sbjct: 59  GGVEAL-RNATGASVHGPARESVPEPLVRLAQGDTVDVLGLRLEVIDVPGHTAGHIAYY- 116

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
             P+     ++F GDTLF GGCGR F
Sbjct: 117 -CPQMDGAPLLFCGDTLFSGGCGRLF 141


>UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_7,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 489

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 48/173 (27%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
 Frame = +1

Query: 190 RITKLYFRALIRNQREAHSSQEDHQYKNM-DVKILPALQDNYMYLIVDKATKEAAIVDPV 366
           +I + + + L    +E    Q +   K     +I       Y Y I  ++ KEA I+DP+
Sbjct: 18  KILQKFNKTLFHFSKEVQLKQSETLGKGFYQQQIFTGCLAEYAYYI--ESNKEAIIIDPL 75

Query: 367 EP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVE 543
              +  L   +E+G  +              G+  L +E    I+ G       ++K + 
Sbjct: 76  RDIQPYLNIAKERGAKIKYVLLTHFHADFIAGHLSLQRETDAQIIMGPRATAPFISKVMN 135

Query: 544 HNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            N   K+G + +Q L TP HT    C F+   EEG    ++TGDTLFLG  GR
Sbjct: 136 DNEFLKVGKVKIQALHTPGHTQESTC-FLLYDEEGKQHSIYTGDTLFLGEVGR 187


>UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=19; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase, putative - Brucella suis
          Length = 257

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 47/150 (31%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
 Frame = +1

Query: 268 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447
           + ++++      DNY  LI D  +   A +D  +   +  A+E +G  L           
Sbjct: 3   QRLEIEQFICRSDNYGVLIHDPESALTATIDAPDAYAIEAALERRGWTLDFIFTTHHHLD 62

Query: 448 XAGGNEDLIKERPGLIVYGGDD---RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHI 618
              GNE L KE+ G+ + G +    +I  + + V+   +F  G   V+ + TP HT G I
Sbjct: 63  HVEGNEPL-KEKFGVSIIGPEAEKAKIPGIDRTVKGGDEFTFGLFKVKVISTPGHTAGGI 121

Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
            Y++  P+     VVFTGDTLF  GCGR F
Sbjct: 122 SYYL--PDA---KVVFTGDTLFALGCGRLF 146


>UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=5; Sphingomonadaceae|Rep:
           Hydroxyacylglutathione hydrolase precursor -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 246

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 6/151 (3%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++  +P L DNY++L+ + A+    +VDP     VL A + +G  +             
Sbjct: 4   LEIVRIPVLSDNYVWLVHEPASGATMVVDPAVADPVLDAAKARGWAITDIWNTHWHPDHT 63

Query: 454 GGN---EDLIKERPGLIVYG---GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH 615
           GGN   ++  K   G  + G     +RI  L   V+     ++G+        P HT GH
Sbjct: 64  GGNAAIKEAAKAWGGCTITGPAAEHERIPTLDVLVKGGDTVRLGDHVADVWDVPAHTAGH 123

Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           I Y        +D+ +F GDT+F  GCGR F
Sbjct: 124 IAYHF-----ADDAAIFVGDTMFAMGCGRLF 149


>UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=1; Trypanosoma brucei|Rep:
           Hydroxyacylglutathione hydrolase, putative - Trypanosoma
           brucei
          Length = 464

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 55/173 (31%), Positives = 77/173 (44%), Gaps = 25/173 (14%)
 Frame = +1

Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE------EQGVNLXXXX 426
           Y  + V  +P L DNY Y I+   TK  A+VDP +P  VL  +E      +    +    
Sbjct: 129 YDGVFVMPVPVLLDNYAYFILSCKTKRCAVVDPADPTLVLNMLEVVRNLTQIDFMITDIL 188

Query: 427 XXXXXXXXAGGNEDL------IKER------PGLIVYGGD-DRIGALTKKVEHNTKFKI- 564
                   AGGN ++        ER      P L +YG + DR  A  K ++ + +  + 
Sbjct: 189 TTHKHWDHAGGNMEMRALSQCSSERCRALLSPELNIYGSEVDRPHACNKLIKGSDELVVA 248

Query: 565 -GNLNVQCLFTPCHTTGHICYFV--TAPEEGNDS--VVFTGDTLFLGGCGRFF 708
            G   V  L TP HT G + + V    P+EG      +FTGD +F GGCG  F
Sbjct: 249 GGGAKVVVLSTPGHTGGSVMFLVGDALPKEGEPQRLALFTGDCVFCGGCGALF 301


>UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Psychrobacter|Rep: Hydroxyacylglutathione hydrolase -
           Psychrobacter sp. PRwf-1
          Length = 259

 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 40/140 (28%), Positives = 63/140 (45%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +PA  DNY++ +V+   K+A ++DP + + V   +E+ G+ L             GG  +
Sbjct: 8   IPAFTDNYIWALVNDTNKQAIVIDPGQAQPVADYLEQYGLELTAIWITHHHHDHVGGVAE 67

Query: 469 LIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
           L +  P   V    +      + V+  +         Q    P HT  H+ Y +   +EG
Sbjct: 68  LRELYPMTHVVASAEHGVKPDQVVKEGSSVSAWGYTAQVWAVPGHTQSHLAYVL--DKEG 125

Query: 649 NDSVVFTGDTLFLGGCGRFF 708
           +   VF GDTLF  GCGR F
Sbjct: 126 HKQ-VFCGDTLFSAGCGRVF 144


>UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=2; Buchnera aphidicola|Rep: Probable
           hydroxyacylglutathione hydrolase - Buchnera aphidicola
           subsp. Acyrthosiphon pisum (Acyrthosiphon pisumsymbiotic
           bacterium)
          Length = 251

 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M +K +  L DNY++++++  +    I+DP   + +++ +E +   L             
Sbjct: 1   MILKKISILSDNYVWVLLN-TSGSCIIIDPGLSEPIIQEIERKKWRLRAILLTHNHIDHT 59

Query: 454 GGNEDLIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG   +I+  P + V+G  + R   + K V H  +  + +      FTP HT+GH+ Y+ 
Sbjct: 60  GGTRKIIEYFPKISVFGPKETRQHGVNKIVSHGDRIILLDKIFYVFFTPGHTSGHVSYY- 118

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
                 +   +F GDTLF  GCGR F
Sbjct: 119 ------SQPYIFCGDTLFSAGCGRVF 138


>UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 3 SCAF15037, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 227

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 29/47 (61%), Positives = 39/47 (82%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414
           M V++LPAL DNYMYL+VD  ++EAA+VDPVEP  V++AV++ GV L
Sbjct: 49  MRVELLPALSDNYMYLLVDVESREAAVVDPVEPLKVVEAVKKHGVRL 95


>UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Gluconobacter oxydans|Rep: Hydroxyacylglutathione
           hydrolase - Gluconobacter oxydans (Gluconobacter
           suboxydans)
          Length = 259

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 47/147 (31%), Positives = 72/147 (48%), Gaps = 4/147 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATK-EAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450
           +D+K +P L DNY +L+   AT+ + A+VDP E   ++  + +  +++            
Sbjct: 24  LDIKPIPVLSDNYAWLLT--ATEGQRAVVDPGEAGPIMDEIGDGRLDMILLTHHHADHT- 80

Query: 451 AGGNEDLIKERPGLIVYGGDDR---IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621
           AG   D ++ER G  VYG   +   +  L   VE      +G+  ++ L TP H  GH+ 
Sbjct: 81  AG--TDALRERYGAKVYGPRQKREWLPRLDHDVEDGDSLSLGSAQIRVLSTPGHAVGHVS 138

Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           Y V  PE      +F GD LF  GCGR
Sbjct: 139 YVV--PEV---PALFCGDVLFSLGCGR 160


>UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 493

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
 Frame = +1

Query: 331 KATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG 507
           ++ KEA ++DP+ E +  ++  +++G  +              G+ DL K+    IVYG 
Sbjct: 49  ESEKEAIVIDPLRETEPYIEYAKKRGATIKYILLTHFHADFISGHVDLAKKTGAKIVYGP 108

Query: 508 DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL 687
             +            K  IG +N++ L TP HT    CY +   E      VFTGDTLFL
Sbjct: 109 TAKASFDFHLATDGEKIPIGKVNIEVLHTPGHTQESSCYLLLDGE--RQHAVFTGDTLFL 166

Query: 688 GGCGR 702
           G  GR
Sbjct: 167 GEVGR 171


>UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Pasteurellaceae|Rep: Hydroxyacylglutathione hydrolase -
           Mannheimia haemolytica PHL213
          Length = 235

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 40/145 (27%), Positives = 66/145 (45%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           + +  +PAL+DNY++ I  +  ++  I+DP E +  L  + +  +NL             
Sbjct: 2   LQITPIPALKDNYIWAI--RNGQDVIIIDPSEHQPALNFIAKNALNLTAILITHNHHDHT 59

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
            G   ++++ P + VYG  +        V       +   +V+ + +  HT GHI Y   
Sbjct: 60  DGVSGIVEQYPNIPVYGPQEVAEFANVIVSPEQHISLFGYDVRIIESGGHTAGHISYLF- 118

Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708
               G D  +F GD LF GGCGR F
Sbjct: 119 ----GYD-YLFCGDALFSGGCGRVF 138


>UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrolase
           GloB; n=1; Idiomarina baltica OS145|Rep: Probable
           hydroxyacylglutathione hydrolase GloB - Idiomarina
           baltica OS145
          Length = 252

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M V  + A  DNY++LI +       +VDP + K V++ ++    ++             
Sbjct: 1   MRVHPVKAFDDNYIWLI-ESTQDRVVVVDPGDDKPVIEWLKANKKDIAGYLITHHHHDHT 59

Query: 454 GGNEDLIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG E L K R     YG D+  I  +   V      +I  L    L TP HT  HI ++ 
Sbjct: 60  GGLEAL-KARFPATSYGPDNPAIKGIDYAVMEGDTVQIAGLRFDVLATPGHTLDHISFY- 117

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
                  D+ +F GDTLF GGCGR F
Sbjct: 118 ------GDTALFCGDTLFSGGCGRMF 137


>UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=10; Chlorobiaceae|Rep:
           Hydroxyacylglutathione hydrolase, putative - Chlorobium
           tepidum
          Length = 215

 Score = 63.3 bits (147), Expect = 6e-09
 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           N+ YL  DKAT EA  VDP   PK ++ A   +G  L              GNE+  +  
Sbjct: 15  NFGYLCADKATGEAFAVDPSNSPKVLVDAAARKGWQLVRAFCTHGHADHTNGNEEF-ERL 73

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
            G+ V    DR   L  +V H   F +G   V+ + TP HT   IC             +
Sbjct: 74  TGIRVLLFGDRDARLGIEVMHGASFPLGEGVVEIIHTPGHTLDSICLLA-------GDAL 126

Query: 664 FTGDTLFLGGCG 699
           FTGDTLF+G  G
Sbjct: 127 FTGDTLFVGKVG 138


>UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Oceanobacter sp. RED65|Rep: Probable
           hydroxyacylglutathione hydrolase - Oceanobacter sp.
           RED65
          Length = 264

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           LP ++ N  Y  + +   +  +VDP + + ++  + EQ ++L              G  D
Sbjct: 7   LPIIEHNGNYAWIIEHAGKVTVVDPGDAQPIINHLREQDLDLDYILVTHKHWDHVNGILD 66

Query: 469 LIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV--TAP 639
           +    P  +VYG G   I  L   +      ++  L+ +   TP HT  HI ++   T P
Sbjct: 67  MKNAFPNAVVYGTGHADIPGLDHPILGGEPLELMGLSWKTWHTPGHTLDHIVFYTETTNP 126

Query: 640 EEGNDSVVFTGDTLFLGGCGRFF 708
           E  +   +F+GD +F  GCGR F
Sbjct: 127 EGESQGHIFSGDNIFACGCGRMF 149


>UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein;
           n=4; Alphaproteobacteria|Rep: Metallo-beta-lactamase
           family protein - Oceanicaulis alexandrii HTCC2633
          Length = 255

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 44/147 (29%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           ++++  P LQDNY +LI    T   A +D  E   +L+  +     +            A
Sbjct: 3   LEIRQFPCLQDNYGFLIRCSETGATACIDTPEADVILEESQTLDWPIRAIWNTHHHWDHA 62

Query: 454 GGNEDLIKERPGLIVYGGDDR--IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
           GGNE + +     IV    +   IG + + V       +GNL  + +    HT GH+ Y+
Sbjct: 63  GGNEAIRQATGARIVAPRAEAATIGHVDQPVAAGDAVALGNLTARVMDVGGHTLGHVAYW 122

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
               EE    V F GD+LF  GCGR F
Sbjct: 123 F---EEAG--VAFVGDSLFALGCGRMF 144


>UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=2; Prochlorococcus marinus|Rep: Putative
           hydroxyacylglutathione hydrolase - Prochlorococcus
           marinus (strain AS9601)
          Length = 303

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 46/162 (28%), Positives = 70/162 (43%), Gaps = 3/162 (1%)
 Frame = +1

Query: 232 REAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVN 411
           R  HS+      K  ++  L  L DN ++L+     K   ++DP   + V++ + E   +
Sbjct: 50  RILHSNLTMEFNKARNIIGLRVLSDNVIWLMAKD--KSVVVIDPSVHEPVIRYINENNFH 107

Query: 412 LXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDD---RIGALTKKVEHNTKFKIGNLNVQ 582
           L             GG + LI++ P + V        RI      VE      I    V+
Sbjct: 108 LEAILQTHHHSDHIGGTKSLIEKWPNVKVIASSKEKKRIPFQNVSVEDGETLNILGEEVK 167

Query: 583 CLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
            +    HT+ HI +F+     G + V+F GDTLF GGCGR F
Sbjct: 168 IIEVLGHTSSHIAFFLN----GENPVLFIGDTLFSGGCGRIF 205


>UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein;
           n=1; Lentisphaera araneosa HTCC2155|Rep:
           Metallo-beta-lactamase family protein - Lentisphaera
           araneosa HTCC2155
          Length = 222

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI-K 477
           DN++YLI DK T + A+VDP  +   + +A EE    +              G + ++ +
Sbjct: 13  DNFIYLIKDKKTSDIAVVDPAWDVDAIFRAAEEMEGEIKEVFLTHSHYDHVNGVDQVLHR 72

Query: 478 ERPGLIVYGGDDRI--GA-LTKKVEHNTKF-KIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
               L ++  +DR   GA    K+     F K+G++ ++   TP HT G +CY +     
Sbjct: 73  SDAKLHIHKIEDRFWGGAGRNAKLHSGGDFIKLGSIELKIHHTPGHTPGSVCYEL----- 127

Query: 646 GNDSVVFTGDTLFLGGCGR 702
             D+ +FTGDT+F+ GCGR
Sbjct: 128 --DNHLFTGDTVFVYGCGR 144


>UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase
           precursor; n=44; Bacteria|Rep: Hydroxyacylglutathione
           hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1
          Length = 269

 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +PA  DNY++ I +   K A +VDP +   VL+ +++ G+ L             GG   
Sbjct: 12  IPAFDDNYIWCIHNG--KSALVVDPGDAVPVLEYLKQSGLRLTGILITHHHADHTGGILA 69

Query: 469 LI----KERPGLIVYGGDDRIGALTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHICYFV 630
           L+    K+ P  ++      I   T+  + + K +I +  +++Q    P HT  HI YF 
Sbjct: 70  LLDALGKDIP--VIGPAGSNIPGRTQIAKADDKIEITSPRISLQVYEVPGHTLSHIAYFA 127

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
                  + ++F GDTLF  GCGR F
Sbjct: 128 NMQANVVEPMLFCGDTLFASGCGRLF 153


>UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1;
           Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain
           protein - Geobacter uraniumreducens Rf4
          Length = 233

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 42/151 (27%), Positives = 67/151 (44%), Gaps = 6/151 (3%)
 Frame = +1

Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXX 441
           Y+   ++I      NY Y+I+D+ + EAAIVDP      L+  ++E G            
Sbjct: 13  YQVFPLRICYQFMINYCYIILDRFSGEAAIVDPAWDLEALQGKLQEMGARPTMILLTHSH 72

Query: 442 XXXAGGNEDLIKERPGLIVYGGDDRIGALTK-----KVEHNTKFKIGNLNVQCLFTPCHT 606
                    L++E    ++    +R             EH  + ++G   + CL TP HT
Sbjct: 73  YDHVNLVAPLVREYDPKVILSRQERDYYQFSCDNLFAAEHLDQIRLGETLINCLLTPGHT 132

Query: 607 TGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           TG +CY ++         +FTGDT+F+ GCG
Sbjct: 133 TGSMCYLLS-------HSLFTGDTVFVEGCG 156


>UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione
           hydrolase - Magnetococcus sp. (strain MC-1)
          Length = 254

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 2/147 (1%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           ++V  LPA +DNY++    +     A+VDP + + V   +++ G+ L             
Sbjct: 5   LEVTPLPAWEDNYIWCFPTEPGA-VAVVDPGQAEPVTDYLQQHGLRLSHILLTHHHGDHI 63

Query: 454 GGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
            G   L ++    ++    D  R+  L + +     F +G   V    TP HT+GH+CY 
Sbjct: 64  DGVAPLQRKHHARVLGSALDAHRLPPLDEALRGGQTFCLGPHQVDTYHTPGHTSGHLCYH 123

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +          +F GDTLF  GCGR F
Sbjct: 124 IA-------DCLFAGDTLFSYGCGRLF 143


>UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Buchnera aphidicola (Baizongia pistaciae)|Rep:
           Probable hydroxyacylglutathione hydrolase - Buchnera
           aphidicola subsp. Baizongia pistaciae
          Length = 249

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M +     L DNY++++ + ++K+  I+DP E  +V+K +++  +N              
Sbjct: 1   MKIIFTKVLFDNYVWIMFN-SSKDCIIIDPGESNSVIKKIKKLNLNPKIILLTHNHLDHI 59

Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKK-VEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
            G ++L+ + P + +YG  +     TK  +++    +I N     + TP HT GH  Y+ 
Sbjct: 60  QGVKNLLYKYPEISIYGPLETQFCGTKNLIDNRNTIEILNTKFYIIPTPGHTNGHTAYYC 119

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGR 702
                     +F GD++F GGCGR
Sbjct: 120 PP-------FLFCGDSIFSGGCGR 136


>UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=1; Plesiocystis pacifica SIR-1|Rep: Probable
           hydroxyacylglutathione hydrolase - Plesiocystis pacifica
           SIR-1
          Length = 270

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 48/149 (32%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           +P   DN+ +L+V +AT EAA +D    + VL+ VE  G+ L             G ++ 
Sbjct: 1   MPFWTDNFTWLLVCEATGEAAAIDGGVAEPVLEYVEAHGLRLTTILTTHTHPDHIGLHKA 60

Query: 469 LIK-ERPG-LIVYGGDDRIGALT-------KKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621
           L K ER G L V G   R+G +        + V+     ++G L  Q + T  H  GH+ 
Sbjct: 61  LDKAERLGALRVVGSRSRLGTIPGLDGPKGEPVDEGDVVRLGALEGQVMLTEGHIDGHVS 120

Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           Y           ++F GDTLF GGCG  F
Sbjct: 121 YRF-------GELLFCGDTLFAGGCGYLF 142


>UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas
           aromatica RCB|Rep: Beta-lactamase-like - Dechloromonas
           aromatica (strain RCB)
          Length = 265

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++  +PA +DNY++L+     K A +VDP +   VL  +E  G+ L             
Sbjct: 2   LEISFIPAFKDNYIWLLT--RGKRAFVVDPGDAAPVLARLEAGGLMLEGILITHHHADHQ 59

Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG  +L K R    VY  G++ I   +  +       +    V  +  P HT GH+ Y+ 
Sbjct: 60  GGVAEL-KARWQAEVYAPGNESITGCSCPLSGGESIDVLGQKVTVMAVPGHTLGHLAYY- 117

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
            AP       +  GDTLF  GCGR F
Sbjct: 118 -AP-----GALLCGDTLFGAGCGRLF 137


>UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase
           - Moritella sp. PE36
          Length = 258

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 4/147 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           ++V  +P   DNY++LI +       IVDP +   VL+ + +Q + L             
Sbjct: 2   LEVISIPTFNDNYVWLIKNTENNHCCIVDPGQADPVLQVINQQNLILEAILITHHHYDHI 61

Query: 454 GGNEDLIKERPGLI-VYGG-DDRIGALTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHIC 621
            G  D++      + VY      + A    V  N++  + N  L +  + TP H   H+ 
Sbjct: 62  DGISDILNASTNPVQVYSSIAIDVDAPVTLVTENSQLNLLNNSLALTVMATPGHKREHVV 121

Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           Y+       N +++F+GDTLF GGCGR
Sbjct: 122 YY-------NQTMLFSGDTLFSGGCGR 141


>UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Clostridium|Rep: Hydroxyacylglutathione hydrolase -
           Clostridium tetani
          Length = 201

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 42/160 (26%), Positives = 75/160 (46%), Gaps = 17/160 (10%)
 Frame = +1

Query: 274 MDVKILPA-LQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXX 447
           M++K +P  +     Y+++DK +KE  IVDP  E   +L+ V +    +           
Sbjct: 1   MELKRIPVGMYQANCYILMDKKSKEGIIVDPGDEANLILQTVNKMDCKVKYILLTHGHVD 60

Query: 448 XAGGNEDL---------IKERP------GLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQ 582
                +++         I E+       G+ ++G     GA   K++    FKIG+  ++
Sbjct: 61  HVSAVKEVKDSLKAPVGINEKDEESILKGMDLFGNSQTCGAADIKIKEGDTFKIGDKEIK 120

Query: 583 CLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           C+ TP H+ G +C+ +       ++++FTGDTLF G  GR
Sbjct: 121 CIETPGHSLGGMCFLI-------ENIIFTGDTLFEGSIGR 153


>UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily protein
           precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
           Metallo-beta-lactamase superfamily protein precursor -
           Thiomicrospira crunogena (strain XCL-2)
          Length = 268

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 45/148 (30%), Positives = 67/148 (45%), Gaps = 3/148 (2%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKAT--KEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447
           M +  LP L DNY ++I  +    K A IVDP E + V+   EE  + L           
Sbjct: 1   MKIVGLPTLSDNYTWVIQSENADDKRAWIVDPGESQKVIHYFEENQLQLDGILLTHHHYD 60

Query: 448 XAGGNEDLIKERPGL-IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624
              G   ++     + IV         +T  V+   + ++ N   Q + TP HT  HIC+
Sbjct: 61  HTDGIMGVMDALGEVAIVSNAQGPFKPVTHPVKEGDQVQVLNETFQVIETPGHTDEHICF 120

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +   PE      +F+GDTLF GGCG+ +
Sbjct: 121 Y--HPE-----ALFSGDTLFTGGCGKIW 141


>UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione
           hydrolase GloB; n=1; Methylophilales bacterium
           HTCC2181|Rep: putative hydroxyacylglutathione hydrolase
           GloB - Methylophilales bacterium HTCC2181
          Length = 223

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           DNY++LI D   +  AIVDP + K V+  ++   +               GG   +  + 
Sbjct: 2   DNYIWLIKD--CRNVAIVDPGDAKPVIDYLKSNDLYPKAILITHKHYDHIGGVVGIKLQY 59

Query: 484 PGLIVYGGDDRIGALTKKV-EHNTKFKIGNLNVQC--LFTPCHTTGHICYFVTAPEEGND 654
           PG+ +YG           V E  +   I  ++++   L TP HT  HI Y+       ND
Sbjct: 60  PGVKIYGPKISSFDFDYTVLEEGSTLSIEGIDIKLNVLETPGHTDDHIAYY-------ND 112

Query: 655 SVVFTGDTLFLGGCGRFF 708
            V+F GDTLF  GCGR F
Sbjct: 113 EVLFCGDTLFACGCGRLF 130


>UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase,
           putative; n=4; Rhodobacteraceae|Rep:
           Hydroxyacylglutathione hydrolase, putative -
           Silicibacter pomeroyi
          Length = 255

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 42/147 (28%), Positives = 63/147 (42%), Gaps = 2/147 (1%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++  +P L DNY YLI D    + A+VD  E   +   ++ +G +L             
Sbjct: 3   LEIVTVPCLSDNYAYLIHDADAGKTALVDAPEAAPIQSELDRRGWSLDQVWLTHHHWDHV 62

Query: 454 GGNEDL-IKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
            G   L  + +P +I    D  R+  L   V    +F +G   V+ L    HT GHI + 
Sbjct: 63  DGLAALRDRYKPTVIGAEADAHRLPPLDLAVSEGDRFDLGGAPVEVLDVSGHTVGHIAFH 122

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +          VFT D+L   GCGR F
Sbjct: 123 LP-----TGKAVFTADSLMALGCGRLF 144


>UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular
           organisms|Rep: ENSANGP00000000940 - Anopheles gambiae
           str. PEST
          Length = 248

 Score = 59.7 bits (138), Expect = 7e-08
 Identities = 40/133 (30%), Positives = 57/133 (42%), Gaps = 2/133 (1%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y YL+ D  TKEA ++DPV  + K   + ++E G  L              G   L +  
Sbjct: 28  YSYLLADITTKEAILIDPVLEQAKRDAQLIKELGFTLKYALNTHMHADHVTGTGFLKQLL 87

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
           PG +            K +  N   + G   ++ + TP HT G  C      E+G   + 
Sbjct: 88  PGTVSVISQSSGAKADKHLVDNETVQFGRHELRAMSTPGHTNG--CMTFLVEEQG---IA 142

Query: 664 FTGDTLFLGGCGR 702
           FTGDTL + GCGR
Sbjct: 143 FTGDTLLIRGCGR 155


>UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9;
           Xanthomonadaceae|Rep: Hydroxyacylglutathione hydrolase -
           Xylella fastidiosa
          Length = 258

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 1/141 (0%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           LPA  +NY++ ++    + A IVDP +   +L+A   +G+               GG  +
Sbjct: 6   LPAFDNNYIWTLIAPDGR-AIIVDPGQALPILEA-HSKGLIPTAILLTHHHADHIGGVPE 63

Query: 469 LIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
           L++  P L +Y   D RI     ++       I  L  Q + TP HT  H+ +       
Sbjct: 64  LLERWPTLPIYAPHDTRIALNYHRIGEGDSLNILGLRFQVIHTPGHTHSHLTFI------ 117

Query: 646 GNDSVVFTGDTLFLGGCGRFF 708
           GND ++F GDTLF  GCG+ F
Sbjct: 118 GND-LLFCGDTLFSLGCGQIF 137


>UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Thiobacillus denitrificans ATCC 25259|Rep:
           Hydroxyacylglutathione hydrolase - Thiobacillus
           denitrificans (strain ATCC 25259)
          Length = 256

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           LPA +DNY+++  D   K A  VDP +P  +   ++ +G+ L             GGN  
Sbjct: 7   LPAFEDNYIWVWHD--AKYAVAVDPGDPAVLSTYLDSRGLALAAVLVTHHHRDHTGGNTW 64

Query: 469 LIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQC--LFTPCHTTGHICYFVTAP 639
           L ++R    +Y  D+ RI A++  V       +  L +    L TP HT  H+ Y     
Sbjct: 65  L-RQRYNCAIYAPDNPRIPAVSHVVRGGDSVAVPELGLALAVLATPGHTLDHVSYV---- 119

Query: 640 EEGNDSVVFTGDTLFLGGCGRFF 708
             GN  + F GDTLF  GCG+ F
Sbjct: 120 --GNGHL-FCGDTLFGCGCGKLF 139


>UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein;
           n=1; Beggiatoa sp. PS|Rep: Metallo-beta-lactamase family
           protein - Beggiatoa sp. PS
          Length = 229

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 6/139 (4%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           +N++YLI D  +   A+VDP  E   ++   + QG+ +              G  +L+  
Sbjct: 19  ENFIYLIQDHHSNRTAVVDPAWEVPKIIALAQHQGLQITDVLLTHSHHDHTNGLTELLNS 78

Query: 481 RPGLI-VYGGDDRIGA--LTKKVEHNTK--FKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
               + +   +++  A  LTK   H+     ++G  +++   TP HT G  CY++     
Sbjct: 79  YDAQVHLLKAEEQFWAHELTKPTVHHGSDTIQLGKTDIEIWHTPGHTPGSACYYL----- 133

Query: 646 GNDSVVFTGDTLFLGGCGR 702
             D  + TGDTLF+ GCGR
Sbjct: 134 --DGHLITGDTLFIFGCGR 150


>UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 536

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 26/174 (14%)
 Frame = +1

Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPK------TVLKAVEEQGVNLXXXX 426
           Y+ + V  +P L DNY YLI+  ATK+ A+VDP +PK      TV++ +      L    
Sbjct: 200 YRGVAVVPVPLLADNYAYLILSFATKKCAVVDPADPKLVMYMLTVVRYLTGVEFVLTDIL 259

Query: 427 XXXXXXXXAGGNEDLIKERPG-------------LIVYGGD-DRIGALTKKVEHNTKFKI 564
                   AGGN + ++                 L +YG   D   A T  VE      +
Sbjct: 260 TTHKHWDHAGGNLEFMQHLQNKSDAEITELLDAQLKIYGSAIDNPHACTNFVEDGNVLTV 319

Query: 565 --GNLNVQCLFTPCHTTGHICYFVTAPEEGND----SVVFTGDTLFLGGCGRFF 708
             G + V    +P HT G + + +      +D      +FTGD +F GGCG  F
Sbjct: 320 AGGGVTVAVFSSPGHTVGSVMFLLGDALMDSDVPQRLALFTGDCIFCGGCGAMF 373


>UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2;
           Thermoprotei|Rep: Zn-dependent hydrolase - Cenarchaeum
           symbiosum
          Length = 203

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 43/145 (29%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
 Frame = +1

Query: 274 MDVKILPALQ-DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXX 447
           M V  LP  Q  N+ Y++ D+ T + A++DP  +  TV++ V   G++            
Sbjct: 1   MKVHQLPVGQMQNFCYVVSDEETGKCAVIDPSWDLDTVMETVTRNGLSAEYVINTHHHFD 60

Query: 448 XAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
              GNE  I  R G  +   ++        V   ++ +IG+  +  L TP H+   IC  
Sbjct: 61  HTVGNE-AIAGRTGARIIQHEESELKHDITVRDGSEIRIGSTMLSVLHTPGHSRDSICLV 119

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGR 702
                   D  +FTGDTLF+G CGR
Sbjct: 120 -------GDGKIFTGDTLFVGSCGR 137


>UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to CG4365-PC, partial -
           Strongylocentrotus purpuratus
          Length = 68

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%)
 Frame = +1

Query: 205 YFRALIRNQ-REAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPK 375
           + + ++R Q R  HS+       +M + +L AL+DNYMYL+ D+ATKEAAIVDPV P+
Sbjct: 10  HIQTVLRPQLRLCHSASTVTSLPDMKITLLSALEDNYMYLLTDEATKEAAIVDPVNPE 67


>UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15;
           Gammaproteobacteria|Rep: Zn-dependent hydrolase -
           Francisella tularensis subsp. novicida (strain U112)
          Length = 228

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 2/133 (1%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPVE--PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y Y++  + T++A I+D V       LK ++E  + L                  L KE 
Sbjct: 14  YTYILACEQTRQAVIIDSVRFNVNQYLKLLKELDLKLIYAIDTHVHADHVTAAGILRKET 73

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
              IV GG+ +    TKKV      + GN  ++ L+TP HT    C F+T      ++++
Sbjct: 74  GCDIVIGGESKAECATKKVFDGDILEFGNYQLKALYTPGHTDDSYC-FIT------ENML 126

Query: 664 FTGDTLFLGGCGR 702
           FTGDTL + G GR
Sbjct: 127 FTGDTLLIRGSGR 139


>UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Acetobacteraceae|Rep: Hydroxyacylglutathione hydrolase -
           Acidiphilium cryptum (strain JF-5)
          Length = 243

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 42/150 (28%), Positives = 59/150 (39%), Gaps = 2/150 (1%)
 Frame = +1

Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXX 444
           ++   +  +P L DNY +L+       +A VDP +    ++AVE  G  L          
Sbjct: 5   HRGFTITRVPMLADNYAWLVAHGGA--SAFVDPADAAAAIEAVEAAGGRLDWVLLTHHHD 62

Query: 445 XXAGGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHI 618
               G  DL       I     D  R+  L   +       +G   V+ + TP HT GH+
Sbjct: 63  DHIAGAVDLAARFGARIAGNAADAARLPRLDAALAPGQTIDLGGEAVRMIATPGHTVGHV 122

Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
            Y         D+    GDTLF  GCGR F
Sbjct: 123 TYLF------GDAAAACGDTLFSLGCGRMF 146


>UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 538

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 1/133 (0%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           +Y Y I  ++  EAAI+DP+ E K        +G  +              G+  L  + 
Sbjct: 95  SYTYYI--ESNGEAAIIDPLRETKPYTDLAARRGAKIKYILESHFHADFVSGHISLANKT 152

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
              I+YG   +        +   + ++GN+ +Q L TP HTT   C F+    +     V
Sbjct: 153 GAKIIYGPGAQALYDIHVAKDGEEIQLGNIKLQVLHTPGHTTESSC-FLLKDSKNQPHSV 211

Query: 664 FTGDTLFLGGCGR 702
           +TGDTLFLG  GR
Sbjct: 212 YTGDTLFLGEVGR 224


>UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein;
           n=14; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Shewanella oneidensis
          Length = 267

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 45/155 (29%), Positives = 64/155 (41%), Gaps = 10/155 (6%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           + +  + A  DNY++++     +   +VDP +   VL  +    + L             
Sbjct: 2   LTITAINAFNDNYIWVLQQDTQQAVYVVDPGDVNVVLDYLNAHQLTLAGILITHHHRDHT 61

Query: 454 GGNEDLI---KERPG--LIVYGGDDRI--G---ALTKKVEHNTKFKIGNLNVQCLFTPCH 603
           GG   L+   ++  G  L VYG       G   A+  ++         N  VQ L  P H
Sbjct: 62  GGIAALVAYVEQTTGHTLAVYGPQSEAIQGVNIAIEPQITQILHLPFLNSPVQVLSVPGH 121

Query: 604 TTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           T GHI Y V       D  +F GDTLF GGCGR F
Sbjct: 122 TAGHIAYLV-------DGALFCGDTLFSGGCGRLF 149


>UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein;
           n=14; Bacteria|Rep: Metallo-beta-lactamase domain
           protein - Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 238

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 3/143 (2%)
 Frame = +1

Query: 283 KILPALQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           ++  A    Y YLI D AT+EAA+VDPV  + +  LK + E G+ L              
Sbjct: 5   QLFDAETSTYTYLIADPATREAALVDPVLEQVERDLKLIRELGLTLKYCLETHVHADHIT 64

Query: 457 GNEDLIKERPGLI-VYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           G   L +E  G   V     +     + + H    ++G++ ++ + T  HT  H+ Y V 
Sbjct: 65  GTGKL-RELTGCQGVVPVQAKAQCADRFIGHGETLQVGSVVIEAIATLGHTDSHMTYRV- 122

Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702
                N   V TGD L + GCGR
Sbjct: 123 -----NGDRVLTGDALLIRGCGR 140


>UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily
           hydrolase; n=8; Cyanobacteria|Rep:
           Metallo-beta-lactamase superfamily hydrolase -
           Synechococcus sp. (strain CC9311)
          Length = 260

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 5/142 (3%)
 Frame = +1

Query: 298 LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIK 477
           L DN +++ V     +A ++DP     +L  ++ +G+ L             GG   L++
Sbjct: 22  LNDNIVWVWV--RGNQAIVIDPAVAAPILDWLDRRGLQLVAVLQTHHHSDHIGGTPGLLQ 79

Query: 478 ERPGL-IVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
                 ++   DD  RI   T  V    + ++    V+ +    HT  HI Y++   E  
Sbjct: 80  RWSSAEVIAAADDKERIPFQTLSVRDGDEIELLGRPVRVMDVRAHTRAHIAYWLPQGEIS 139

Query: 649 ND--SVVFTGDTLFLGGCGRFF 708
               SV+F GDTLF GGCGR F
Sbjct: 140 TSLTSVLFCGDTLFSGGCGRLF 161


>UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 617

 Score = 56.0 bits (129), Expect = 9e-07
 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNE 465
           LP L  +Y YL++  + KEA +VDP    T  L   ++ G+ +              G+ 
Sbjct: 5   LPVLS-HYSYLLI--SGKEALLVDPDRDITAYLDHAKKHGLTIKGVFLTHSHADFVAGHL 61

Query: 466 DLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
           +L++     +            + ++  + FK+G   V+ + TP HT   +C  V +  +
Sbjct: 62  ELVRALNVPVYQNAASGAKYKIEPLKEGSTFKVGAAMVKAVETPGHTPDGMCGLVFSEGD 121

Query: 646 GNDSVVFTGDTLFLGGCGR 702
               ++FTGDTLF+G  GR
Sbjct: 122 DQPKMIFTGDTLFVGSVGR 140


>UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily; n=1; Clostridium
           acetobutylicum|Rep: Predicted Zn-dependent hydrolase of
           metallo-beta-lactamase superfamily - Clostridium
           acetobutylicum
          Length = 199

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 14/143 (9%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y++VD+ + E+ ++DP + P+ +L+A ++   NL                 +L KE    
Sbjct: 16  YILVDEKSNESVVIDPGDAPQAILEAFKDTETNLKFVLLTHGHADHTAAVAELKKEYNVD 75

Query: 493 IVYGGD-------------DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           +    D             D+    TK V+   + + G L ++C+ TP HT G +CY V 
Sbjct: 76  VYMNKDDCKLIENGEYMFGDKSENATKYVDDGDELQFGELKIKCIKTPGHTPGGMCYLV- 134

Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702
                 D+ +F+GDTLF    GR
Sbjct: 135 ------DNYLFSGDTLFNSSIGR 151


>UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Thiomicrospira crunogena XCL-2|Rep:
           Metallo-beta-lactamase superfamily protein -
           Thiomicrospira crunogena (strain XCL-2)
          Length = 229

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 43/134 (32%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPVEPKTVL--KAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y YL+ D+ TKEAA++D V  K     + ++E G+N+              G   L K  
Sbjct: 14  YTYLLWDETTKEAAVIDSVLEKVDRDEQHIKELGLNVKYLLETHIHADHITGAGPLRKRM 73

Query: 484 PG-LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
            G L+V+       A    V+ +  FK+G+  +  L TP HT   I Y +       +  
Sbjct: 74  GGQLVVHKNSGSECADILAVDGDV-FKLGDQEIHVLHTPGHTNNDITYQI-------EGA 125

Query: 661 VFTGDTLFLGGCGR 702
           VFTGDTL +  CGR
Sbjct: 126 VFTGDTLMVRDCGR 139


>UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9;
           Rhodobacterales|Rep: Hydroxyacylglutathione hydrolase -
           Silicibacter sp. (strain TM1040)
          Length = 271

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 7/152 (4%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++  +P L DNY YL+  K     A++D  E + +L A+E +  +L             
Sbjct: 17  LEIVTVPCLADNYAYLV--KGPDGVALIDAPEAEPILTALEARDWSLGVIMITHHHHDHV 74

Query: 454 GGNEDLIKERPGLIVYGGD---DRIGA--LTKKVEHNTKFKIGNLNVQC--LFTPCHTTG 612
           GG   L +E+ G  V G     D+I A  +T  +E    F+ G    +C  L  P HT G
Sbjct: 75  GGVAAL-REKFGCPVMGPKAEADKIAAQGVTLDMELEPGFEGGTGAGRCQVLAVPGHTLG 133

Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           HI ++   PE      +F+ D+L + GCGR F
Sbjct: 134 HIAFYY--PEA---PALFSADSLMVMGCGRLF 160


>UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           cellular organisms|Rep: Hydroxyacylglutathione hydrolase
           - Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 263

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           N+ YLI    T EA  +DP++ +  L     +G  +             GGN  +I    
Sbjct: 14  NFNYLIACPETGEALAIDPLDHEKTLATARVKGWQITQVLNTHEHHDHTGGNAAVIAATG 73

Query: 487 GLIV--YGGDDRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657
             ++  +    RI  + + V+     K+G  + ++CL TP HT  HIC            
Sbjct: 74  AKLIAHHKAGGRIAGVDRGVKAGDVIKVGKTVELECLDTPGHTMCHIC----LRSHTEQP 129

Query: 658 VVFTGDTLFLGGCG 699
            +F+GDTLF  G G
Sbjct: 130 ALFSGDTLFNAGAG 143


>UniRef50_Q0RV06 Cluster: Possible hydrolase; n=11;
           Actinomycetales|Rep: Possible hydrolase - Rhodococcus
           sp. (strain RHA1)
          Length = 496

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 1/130 (0%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YLI D++T  A +VDP    T  L      G+ +              G+ +L++     
Sbjct: 53  YLIGDESTGRAVVVDPRRDITEYLDDARTHGLTIDGVINTHFHADFVSGHLELVEATGAW 112

Query: 493 IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 672
           I +G         +++ H     +G ++++ L TP HT   I   +    + + + V TG
Sbjct: 113 IGFGEAAETDYPIRRLAHGEHISLGRVDLEILSTPGHTWESISVLIRETPDADPTAVLTG 172

Query: 673 DTLFLGGCGR 702
           D+LF+G  GR
Sbjct: 173 DSLFIGDVGR 182


>UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Sodalis glossinidius str. 'morsitans'|Rep: Putative
           hydroxyacylglutathione hydrolase - Sodalis glossinidius
           (strain morsitans)
          Length = 250

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           M++  +PAL DNY++L+ +   +   +VDP +   VL+A+ +  +               
Sbjct: 1   MNLISIPALADNYIWLLHND-DRRCLVVDPGDATPVLQALADHRLTPVAVLLTHHHQDHV 59

Query: 454 GGNEDLIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           GG  +L++  P + VYG ++ R    T+ V       + +     +  P HT GHI ++ 
Sbjct: 60  GGVSELLQHFP-VPVYGPEETRSKGATQIVNEGDSLTLLDHTFSIMALPGHTLGHIGFY- 117

Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +AP       +F GDT+F  G GR F
Sbjct: 118 SAP------WLFCGDTVFSAGSGRLF 137


>UniRef50_A5INW0 Cluster: Beta-lactamase domain protein; n=30;
           Staphylococcus|Rep: Beta-lactamase domain protein -
           Staphylococcus aureus subsp. aureus JH9
          Length = 444

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE-RPG 489
           YL+  + T EA I+DPV   +  ++  + +G+ +            A G  D+ K     
Sbjct: 16  YLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHADFASGIRDVAKRLNAN 75

Query: 490 LIVYG-GDDRIG-----ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651
           + V G G+D +G     + T+ V+H    ++GN+ ++ L TP HT   I + +T    G 
Sbjct: 76  IYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHTPESISFLLT-DLGGG 134

Query: 652 DSV---VFTGDTLFLGGCGR 702
            SV   +F+GD +F+G  GR
Sbjct: 135 SSVPMGLFSGDFIFVGDIGR 154


>UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=9; Rhodobacteraceae|Rep: Probable
           hydroxyacylglutathione hydrolase - Rhodobacter
           capsulatus (Rhodopseudomonas capsulata)
          Length = 256

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 2/147 (1%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           +++  +P L DNY +L  D AT    +VD  E   VLK + ++   L             
Sbjct: 3   LELTPIPCLTDNYAWLWHDTATDTVVVVDVPEAAPVLKVLTDRRWQLHHILITHHHADHI 62

Query: 454 GGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627
            G E L +     +     D  R+  L   V       +G    Q +    HT GHI ++
Sbjct: 63  AGVEALAQATGAKVAGAAADAHRLPPLDHPVAPGDVLHLGMEAAQVIAADGHTLGHIAWY 122

Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           +  P  G   ++F+GD+L   GCGR F
Sbjct: 123 L--PGAG---LLFSGDSLMSWGCGRLF 144


>UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3;
           Leptospira|Rep: Zn-dependent hydrolase - Leptospira
           borgpetersenii serovar Hardjo-bovis (strain JB197)
          Length = 269

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 4/135 (2%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           N+ Y++ +  T E   +DP + + + K ++ +G  L              GN  L+ +R 
Sbjct: 14  NFTYILRNSETSETLSIDPYDSEQIEKFLDSKGWTLDFLLNTHEHEDHTSGNTGLV-QRY 72

Query: 487 GLIVYGGDDRIGALTKKVEHNTK----FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND 654
           G  VY   + IG +        K     +     ++ L TP HT  H+C  +   E    
Sbjct: 73  GCTVYSHPEGIGKIPHATHPLKKGDFLLRSSKEYLEILDTPGHTFCHVCLLLV--ENQKP 130

Query: 655 SVVFTGDTLFLGGCG 699
             +FTGDT+F  G G
Sbjct: 131 KAIFTGDTIFNAGVG 145


>UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter
           sp. BAL39|Rep: Rhodanese-like protein - Pedobacter sp.
           BAL39
          Length = 459

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 1/133 (0%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           +Y Y I+  + K+  ++DP   P+       + G  +               + ++    
Sbjct: 13  HYSYAILSNSEKKVILIDPARNPQPYYDFAAKHGATIVGVIETHPHADFVSSHLEIHMTT 72

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
              I       +       +   +  +G L ++ + TP H+   IC  +   + GND  V
Sbjct: 73  SAKIYSHTLTGVSYPQTPFDEGAEIVLGELKLKSIHTPGHSPDSIC--IILEQNGNDKAV 130

Query: 664 FTGDTLFLGGCGR 702
           FTGDTLF+G CGR
Sbjct: 131 FTGDTLFIGDCGR 143


>UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Gammaproteobacteria|Rep: Hydroxyacylglutathione
           hydrolase - Halorhodospira halophila (strain DSM 244 /
           SL1) (Ectothiorhodospirahalophila (strain DSM 244 /
           SL1))
          Length = 255

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 44/142 (30%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           L AL DNY+++  D +   A  VDP +   V   + +  + L             GG  +
Sbjct: 7   LAALADNYIWMARDASGTTAFAVDPGDAAVVEAWLHDHQLRLAAVLVTHHHGDHTGGVAE 66

Query: 469 LIKERPGLIVYG-GDDRIGALTKKVEHNTKFKI-GNLNVQCLFTPCHTTGHICYFVTAPE 642
           L  ER  + V+G   + I  +   +     F + G    + L  P HT GHI Y      
Sbjct: 67  LA-ERHRVPVFGPATETIPTVDHPITGGEHFSLEGFGEFRVLDCPGHTAGHIAYLW---- 121

Query: 643 EGNDSVVFTGDTLFLGGCGRFF 708
           EG+   +F+GD LF GGCGR F
Sbjct: 122 EGH---LFSGDALFAGGCGRVF 140


>UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 235

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 7/138 (5%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLK-AVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           N +Y+I+D  T+  A+VDP     ++K  + +    +                  ++K  
Sbjct: 29  NNVYIIIDSQTRHTAVVDPAWNIGLIKDTLNKLQAEVKVILLTHSHYDHTNLVNSMLKIY 88

Query: 484 PGLIVYGGDDRIGALTKK------VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
           P   VY     +     K      V+     K+G  +++C+ TP HT G +C+FV     
Sbjct: 89  PAK-VYMSKTEVDYYNYKCNSLVPVQDGEVIKLGYTDIKCILTPGHTMGGMCFFV----- 142

Query: 646 GNDSVVFTGDTLFLGGCG 699
             D  +FTGDT+F+ GCG
Sbjct: 143 --DGSLFTGDTIFMEGCG 158


>UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB;
           n=1; Bdellovibrio bacteriovorus|Rep:
           Hydroxyacylglutathione hydrolase GloB - Bdellovibrio
           bacteriovorus
          Length = 251

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 2/149 (1%)
 Frame = +1

Query: 268 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447
           K   V+++P   DNY++++ D AT++A  VDP +   V+  +    ++L           
Sbjct: 3   KKEHVELVPIFDDNYVFILTDDATQKAVAVDPGDAGPVIDFLRANKLDLAAILLTHHHSD 62

Query: 448 XAGGNEDL--IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621
             GG  +L    + P         +I    + ++       G  +   +  P HT GHI 
Sbjct: 63  HIGGVGELKAAFDCPVYAPQKNQKQIPVADQWLKEGDSVTCGPWDFTVMELPGHTLGHIA 122

Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           Y+           +F+GD +F  GCGR F
Sbjct: 123 YW-----NQKHKWLFSGDVIFGLGCGRLF 146


>UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep: Beta-lactamase
           domain protein - Clostridium beijerinckii NCIMB 8052
          Length = 224

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           +N  Y+I++   KEA I+DP  + + ++  +   GV+L                E L+K 
Sbjct: 16  NNCTYIIINNDIKEAVIIDPAWDLEKIVANLNTNGVSLSSILLTHSHYDHTNLVEPLLKI 75

Query: 481 RPGLIVYGGDDRI---GALTKK---VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642
                VY     I   G   K    V  + K  IG L + C+ TP HT G +C+ +    
Sbjct: 76  F-NCQVYMAKKEINYYGFRCKNLNPVNDSDKISIGKLKMDCVLTPGHTAGGMCFKL---- 130

Query: 643 EGNDSVVFTGDTLFLGGCG 699
              ++ +FTGDT+F+ GCG
Sbjct: 131 ---ENKLFTGDTIFIRGCG 146


>UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 524

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 1/125 (0%)
 Frame = +1

Query: 331 KATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG 507
           ++ K A I+DP+   +  +  + ++G  L               + D+ K     IV+G 
Sbjct: 31  ESDKVAVIIDPMRDYQRYIDLLNQRGATLKYVIETHFHADFVSSHLDIAKITGATIVFGP 90

Query: 508 DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL 687
                   K        +IG++ +Q L TP HT    CY +   E      VFTGDTLFL
Sbjct: 91  TASPKYEIKVASDEEILEIGSVKLQVLHTPGHTPESSCYLLL-DENNTAQCVFTGDTLFL 149

Query: 688 GGCGR 702
           G  GR
Sbjct: 150 GDVGR 154


>UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamily
           protein; n=11; Bacteria|Rep: Possible
           Beta-lactamase-like superfamily protein - Psychrobacter
           arcticum
          Length = 249

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 2/137 (1%)
 Frame = +1

Query: 298 LQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL 471
           L   Y YL+ D+ T +A ++DPV       L  V   G++L                 ++
Sbjct: 10  LSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEVHRLGLDLVYTVDTHIHADHITAALEM 69

Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651
            +     I     DR+  +   +E  T  ++  + +  L TP HT GH  Y         
Sbjct: 70  KRAVGSKIAAPAFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLF------- 122

Query: 652 DSVVFTGDTLFLGGCGR 702
           +  VFTGD L + GCGR
Sbjct: 123 NEQVFTGDALLIDGCGR 139


>UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           cellular organisms|Rep: Hydroxyacylglutathione hydrolase
           - Syntrophus aciditrophicus (strain SB)
          Length = 485

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 2/133 (1%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           Y YL+ D  ++EA ++DP     V L+A   QG  +              G+ +L   R 
Sbjct: 47  YSYLVGD--SREAVVIDPRRDIDVYLEAATFQGYRIVAVLETHRHEDFVLGSVELAA-RT 103

Query: 487 GLIVYGGDDRIG-ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
           G  ++  D +      + V     +KIG L ++ + +P HT G + Y +    +GN  +V
Sbjct: 104 GAEIWHADGQWDYQYGEAVGDGQTWKIGRLKLEAIHSPGHTPGSMSYLLY-DADGNPWMV 162

Query: 664 FTGDTLFLGGCGR 702
           FTGD LF G  GR
Sbjct: 163 FTGDALFAGDVGR 175


>UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2;
           sulfur-oxidizing symbionts|Rep: Beta-lactamase domain
           protein - Ruthia magnifica subsp. Calyptogena magnifica
          Length = 240

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 5/139 (3%)
 Frame = +1

Query: 298 LQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474
           L+D+ ++ I D  TK  AIVDP  +    ++ +  +G  L                ++++
Sbjct: 22  LEDS-IHFIFDHNTKTCAIVDPAWDAPLFIQRIHNKGYILTDIWLTHWHFDHTNAVDEIV 80

Query: 475 KERPGLIVYGGDD----RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642
           K     I  G ++    +I +L + V++N    IGN   + + TP H+ G ICY +    
Sbjct: 81  KATGAKITVGVNEVPYLQIDSLPETVDNNDTIFIGNTPAKIINTPGHSAGGICYLL---- 136

Query: 643 EGNDSVVFTGDTLFLGGCG 699
              D  +  GDTLF+ G G
Sbjct: 137 ---DGHIIAGDTLFVYGAG 152


>UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1;
           Methanoculleus marisnigri JR1|Rep: Beta-lactamase domain
           protein - Methanoculleus marisnigri (strain ATCC 35101 /
           DSM 1498 / JR1)
          Length = 467

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
 Frame = +1

Query: 343 EAAIVDPVEPKTVLKAV-EEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519
           EAA++DP     +  AV E +G+ +              G+ +L +     I++G  +  
Sbjct: 23  EAAVIDPRRDCLIYAAVAEREGMKITKIFETHKNEDYVIGSRELARPTGAEILHGAREEF 82

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE-EGNDSVVFTGDTLFLGGC 696
           G  T   E  T F +G+L ++ L TP HT   I   +      G+  +VFTGD LF G  
Sbjct: 83  GFGTGVHEGET-FTVGSLELEILETPGHTIESISLLLRDRSVSGDPLMVFTGDALFAGDV 141

Query: 697 GR 702
           GR
Sbjct: 142 GR 143


>UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5;
           Shewanella|Rep: Hydroxyacylglutathione hydrolase -
           Shewanella sp. (strain MR-4)
          Length = 295

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 10/155 (6%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           + +  + A  DNY++++   + +   +VDP +   VL  + +  + L             
Sbjct: 30  LTITAINAFNDNYIWVLRQDSQQNVYVVDPGDANVVLDYLHKHQLTLAGILITHHHRDHT 89

Query: 454 GGNEDL---IKERPG--LIVYGGD-DRIGALTKKVEHNTKFKIG----NLNVQCLFTPCH 603
           GG   L   +++  G  L VYG   + I  +   ++      +     +  V  L  P H
Sbjct: 90  GGIAALAAHVEQTTGHTLAVYGPQSEAIQGINLPIDPKPSDTLTLPFIDAPVHILSVPGH 149

Query: 604 TTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           T GHI Y V       D  +F GDTLF  GCGR F
Sbjct: 150 TAGHIAYLV-------DGALFCGDTLFSAGCGRLF 177


>UniRef50_Q71KM2 Cluster: Glyoxalase II; n=8; Plasmodium|Rep:
           Glyoxalase II - Plasmodium falciparum
          Length = 322

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 2/143 (1%)
 Frame = +1

Query: 286 ILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNE 465
           I+P  +DNY Y+  D   +E  +VDP +   +    +++ + +              GN+
Sbjct: 62  IIPFYKDNYSYIFYDDK-EEGIVVDPADYNIINDISKKENIKIKHVLCTHKHSDHNNGNQ 120

Query: 466 DLIKERPGLIVYGGDDRIGA-LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642
              ++   + VYG  +     + + + + T F+I N  +    +  H+   + Y +    
Sbjct: 121 YYYEKN--INVYGIKEYDNKYINQDISNLTHFQINNFKINIFLSNFHSKNQVSYLIENDN 178

Query: 643 -EGNDSVVFTGDTLFLGGCGRFF 708
            +   ++ FTGD LF+ G G+ F
Sbjct: 179 NKSKKNIFFTGDFLFISGIGKNF 201


>UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular
           organisms|Rep: Metallo-beta-lactamase - Methanosarcina
           acetivorans
          Length = 481

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y++  K  K  AI+DP     + ++  + +G+ +              G+ DL  E  G 
Sbjct: 16  YILAGK--KSCAIIDPQRDVEIYIREAKSRGLKITHILETHLHADFVSGHMDLA-ELTGA 72

Query: 493 IVYGGDDRIGALTKK--VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND-SVV 663
            +Y  +           VE +T F+I ++ V+ L TP HT  HI Y V+    G D + V
Sbjct: 73  PIYAPEAAKCEFEHVGLVEGDT-FEIEDMTVKVLETPGHTPEHISYVVSDTSRGPDPTAV 131

Query: 664 FTGDTLFLGGCGR 702
           F GDTLF+G  GR
Sbjct: 132 FCGDTLFVGDVGR 144


>UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5;
           Bacteria|Rep: Hydroxyacylglutathione hydrolase -
           Dinoroseobacter shibae DFL 12
          Length = 256

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 3/137 (2%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           NY  L+ D ++   A VD  +   +  A+++ G  L              G  + IK   
Sbjct: 15  NYGVLLHDPSSGATASVDAGDAAALRTALKKTGWTLSEIWITHHHADHTDGVAE-IKAET 73

Query: 487 GLIVYGGDDR---IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657
           G  V G   +   I  +  +     +F      V+ + TP HT   I +++  P EG   
Sbjct: 74  GCTVIGPKPQSAPIAGVDTRYGDGDRFDFSGHEVRVIHTPGHTIDMINFYL--PAEG--- 128

Query: 658 VVFTGDTLFLGGCGRFF 708
           VVFTGDTLF+ GCGR F
Sbjct: 129 VVFTGDTLFVMGCGRLF 145


>UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=17; Pasteurellaceae|Rep: Probable
           hydroxyacylglutathione hydrolase - Haemophilus
           influenzae
          Length = 238

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 37/140 (26%), Positives = 56/140 (40%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           LPAL DNY++L   +      IVD  E   +   +E+Q   +              G   
Sbjct: 5   LPALNDNYIWLY-QRENLPLIIVDLPETDKLFAWLEKQNATIEAVLLTHEHDDHTQGVSA 63

Query: 469 LIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
             K  P + +YG  +       ++ +  K    N  +  + T  HT  H+ + V      
Sbjct: 64  FKKRYPTVPIYGPQECEKKGATQIVNEGKILTANYQIDVIPTGGHTKQHVSFLV------ 117

Query: 649 NDSVVFTGDTLFLGGCGRFF 708
            D+ +F GD LF  GCGR F
Sbjct: 118 -DNHLFCGDALFSAGCGRVF 136


>UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 468

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 39/146 (26%), Positives = 64/146 (43%), Gaps = 9/146 (6%)
 Frame = +1

Query: 292 PALQDNYMYLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468
           P L  N  YL+ D+ TKE  ++DP    T ++ A E   +++              G  +
Sbjct: 9   PGLAIN-TYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHADFISGARE 67

Query: 469 L---IKERPGLIV--YGGDDRIGALTKK-VEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630
           L   +K  P +    +GG+  + A     V+       G++ ++ L TP HT  HI +  
Sbjct: 68  LKFQLKNAPIIYSSGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWIC 127

Query: 631 TAPEEGNDS--VVFTGDTLFLGGCGR 702
                 +D    +F+GD LF+G  GR
Sbjct: 128 YDETRSHDLPWFIFSGDCLFVGSVGR 153


>UniRef50_A6BZ99 Cluster: Putative uncharacterized protein; n=2;
           Bacteria|Rep: Putative uncharacterized protein -
           Planctomyces maris DSM 8797
          Length = 487

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 14/143 (9%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YL+  + TKEA +VDP       L+    +GV L              G  +L  +R G 
Sbjct: 16  YLVGCQKTKEAVVVDPGRDIDQYLETARREGVKLTAVAETHIHADYVSGARELA-DRVGA 74

Query: 493 IVYGGDDRIGALTKKVEHNTKFK-----------IGNLNVQCLFTPCHTTGHICYFVTAP 639
            +Y  D+  G    K E+ +++K           IGN+  Q L TP HT   I + +T  
Sbjct: 75  KLYVSDE--GPAEWKYEYASQYKSQLLKDGDTFLIGNIQFQVLHTPGHTPESISFLLTDQ 132

Query: 640 EEGNDSV--VFTGDTLFLGGCGR 702
             G      +FTGD +F+G  GR
Sbjct: 133 GGGASEPMGIFTGDFVFVGSIGR 155


>UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3;
           Bacillus|Rep: Hydroxyacylglutathione hydrolase -
           Bacillus amyloliquefaciens
          Length = 230

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 7/155 (4%)
 Frame = +1

Query: 256 DHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXX 432
           DH Y+   +K    +  NY Y+I D++ K A  VDP  E   +   + E  V+L      
Sbjct: 7   DHTYEVHQIKTYHQMWSNYCYIIADRSKKSAIAVDPSWEIDKITDKLHELDVDLSAILLT 66

Query: 433 XXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKK------VEHNTKFKIGNLNVQCLFT 594
                     E L ++     +Y     I     +      +E    F  G   ++ + T
Sbjct: 67  HSHYDHVNLAEPL-QQIYHSDIYMSSAEIDFYQFRCRNLIALEDGQTFAAGGFIIRSILT 125

Query: 595 PCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           P HT G +CY ++         +FTGDT+F  GCG
Sbjct: 126 PGHTAGGMCYLLS-------DHLFTGDTVFTEGCG 153


>UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily
           protein; n=17; Bacteroidetes|Rep: Metallo-beta-lactamase
           superfamily protein - Flavobacteriales bacterium
           HTCC2170
          Length = 492

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 42/164 (25%), Positives = 68/164 (41%), Gaps = 2/164 (1%)
 Frame = +1

Query: 217 LIRNQREAHSSQEDHQYKNMDVK-ILPALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKA 390
           L  NQ E + + + + +  M ++ I      +  Y I  K   EAAI DP+ E +  +  
Sbjct: 3   LYGNQNEHNFTVKFYSHFTMRIEQIYTGCLAHAAYYIESKG--EAAIFDPLREVQPYIDR 60

Query: 391 VEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN 570
             +    +              G+ DL K+    IV+G            E N  F++G+
Sbjct: 61  ANKDNAKVKYVFETHFHADFVSGHLDLKKKTGAQIVFGPTANPNYDALIAEDNQIFELGD 120

Query: 571 LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
             ++ L TP HT     Y +    +    ++ TGDTLF+G  GR
Sbjct: 121 YKIKVLHTPGHTMESTTYLLIDENDKQHGII-TGDTLFIGDVGR 163


>UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 321

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 21/80 (26%)
 Frame = +1

Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF-------VTAPEEGN------------- 651
           K+ ++ T  + G   +  L+ PCHTTGH+ Y        ++  E  N             
Sbjct: 124 KETKNETSIE-GEFQIDFLYVPCHTTGHVLYHFKPHNKTISTEESVNFERQEVTGYNLYS 182

Query: 652 -DSVVFTGDTLFLGGCGRFF 708
            D  +FTGDTLF+GGCGRFF
Sbjct: 183 VDECLFTGDTLFIGGCGRFF 202


>UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1;
           Encephalitozoon cuniculi|Rep: HYDROXYACYL GLUTATHION
           HYDROLASE - Encephalitozoon cuniculi
          Length = 263

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 20/52 (38%), Positives = 30/52 (57%)
 Frame = +1

Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708
           KF+  ++ ++C  TPCHT    C++V       +  + TGDTL   GCG+FF
Sbjct: 124 KFRFKDVEIECFHTPCHTVDSFCFYV------GEKYLATGDTLLFLGCGKFF 169


>UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           unclassified Gammaproteobacteria (miscellaneous)|Rep:
           Hydroxyacylglutathione hydrolase - marine gamma
           proteobacterium HTCC2143
          Length = 258

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           N+ YLI +     A ++DP +   V + + +  ++L              GN +L+ E  
Sbjct: 14  NFTYLI-ELEDGSALVIDPWDAGEVNRLLHQWQLSLRAIINTHEHWDHIQGNPELVAEHS 72

Query: 487 GLIVY--GGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGNDS 657
             +     G  ++  L++ +       +   + ++ L TP HT  H+C+ V   E+G + 
Sbjct: 73  CEVWAHSNGQGKVPGLSRMLTAGELIDLDTGVQLRVLDTPGHTYAHLCFLVL--EQGIEV 130

Query: 658 VVFTGDTLFLGGCG 699
            VFTGDTLF  G G
Sbjct: 131 AVFTGDTLFNAGVG 144


>UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3;
           Methanosarcina|Rep: Metallo-beta-lactamase -
           Methanosarcina acetivorans
          Length = 457

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%)
 Frame = +1

Query: 343 EAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG--DD 513
           EA ++DP     V       +G+ +              G+ +L K     I +G   D 
Sbjct: 23  EAIVIDPRRDCQVYFDLARSKGMKIKYIFETHRNEDYIIGSLELEKLTDAGIYHGSGVDF 82

Query: 514 RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTGDTLFLG 690
           + G + KK     +F  G L +  L TP HT   + Y +T P+ G + + VFTGD LF+G
Sbjct: 83  KYGNILKK--DRQEFIFGALKLTALHTPGHTDESMSYVLTDPDAGKEPIMVFTGDALFVG 140

Query: 691 GCGR 702
             GR
Sbjct: 141 DVGR 144


>UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2;
           Chloroflexus|Rep: Beta-lactamase-like:Rhodanese-like -
           Chloroflexus aurantiacus J-10-fl
          Length = 466

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 40/140 (28%), Positives = 62/140 (44%), Gaps = 11/140 (7%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YLI    T EA ++DP+ + +  L+   ++G+ +              G  +L   R G 
Sbjct: 16  YLIGCAKTGEAMVIDPMRDVEPYLRVAAKEGLRITHVTETHIHADFVSGVRELAA-RTGA 74

Query: 493 IVY---GGDDRIGALTKKVEHNTKFK------IGNLNVQCLFTPCHTTGHICYFVTAPEE 645
            +Y    GD        ++E     K      +GN+ VQ + TP HT  HI + +T    
Sbjct: 75  QMYLSDMGDANWKYAYPEIEKAILVKDGDTWMVGNIKVQVIATPGHTPEHIAFMITDTAG 134

Query: 646 GNDSV-VFTGDTLFLGGCGR 702
            +  + VFTGD LF+G  GR
Sbjct: 135 ADQPMGVFTGDFLFVGDVGR 154


>UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Tetrahymena thermophila SB210|Rep:
           Metallo-beta-lactamase superfamily protein - Tetrahymena
           thermophila SB210
          Length = 498

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 1/120 (0%)
 Frame = +1

Query: 331 KATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG 507
           ++ K+A ++DP+   +  ++  +++   +             GG+ D+ K+    IV G 
Sbjct: 49  ESEKQAILIDPLRDIQQYIEYSQKREAKITHVFLTDFHSDFIGGHVDIQKQADAQIVLGP 108

Query: 508 DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL 687
                    + + N    IG + +Q L+TP HT    C+ +   ++     +FTGDTL+L
Sbjct: 109 TSIADFEFHQAKDNEIISIGKIKMQVLYTPGHTNESTCFLLL--DDERQHAIFTGDTLYL 166


>UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Beta-lactamase-like -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 464

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 12/141 (8%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YL+  + T EA ++DP     V L A +  G+ +              G+ +L  +  G 
Sbjct: 16  YLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHADFVSGSRELA-QITGA 74

Query: 493 IVYGGDDRIGAL----------TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642
            +Y       A            + +     + +GNL ++ L TP HT  H+ + +T   
Sbjct: 75  KLYLSAAGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTP 134

Query: 643 EGNDSV-VFTGDTLFLGGCGR 702
            G++ + +FTGD LF G  GR
Sbjct: 135 AGDEPMGIFTGDLLFAGDVGR 155


>UniRef50_Q1AVJ8 Cluster: Beta-lactamase-like protein; n=4;
           Bacteria|Rep: Beta-lactamase-like protein - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 479

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 7/136 (5%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y I  +AT EA +VDP       L+   + G+ +              G+ +L     G 
Sbjct: 16  YFIGCQATGEAVVVDPRRDIGAYLEMARKNGMRIAAVTETHIHADYLSGSRELAAAT-GA 74

Query: 493 IVYGGDD-----RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND- 654
            +Y  D+     + G   +++    + ++GN+ ++ L TP HT  H+ + VT      + 
Sbjct: 75  TLYLSDEGDEPWKYGFEGERLHDGDEIRVGNVVLKALHTPGHTPEHLSFLVTDGAAAEEP 134

Query: 655 SVVFTGDTLFLGGCGR 702
             + TGD +F+G  GR
Sbjct: 135 GYILTGDFVFVGDLGR 150


>UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=11;
           Proteobacteria|Rep: Metallo-beta-lactamase superfamily -
           Nitrosomonas europaea
          Length = 262

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 4/142 (2%)
 Frame = +1

Query: 295 ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474
           A +DNY++++ ++  + A I+DP +   VL  + +Q +               GG   L+
Sbjct: 9   AFRDNYIWIVHNQ--QFALIIDPGDATPVLTWLRQQKLQPIAILCTHHHHDHTGGIS-LL 65

Query: 475 KERPGLIVYG-GDDRIGALTKKV-EHNTK-FKIGNLNVQCLFTPCHTTGHI-CYFVTAPE 642
            ++  + VYG   ++I  +T  + E +T  F   +L +  L  P HT GHI C+      
Sbjct: 66  VQKFEIPVYGPASEKIPGMTHPLAEGDTLVFPELSLELSILDVPGHTAGHIACH------ 119

Query: 643 EGNDSVVFTGDTLFLGGCGRFF 708
               + +F GDTLF  GCGR F
Sbjct: 120 --GQNRLFCGDTLFACGCGRIF 139


>UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4;
           Bacteria|Rep: Beta-lactamase-like:Rhodanese-like -
           Exiguobacterium sibiricum 255-15
          Length = 468

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 10/139 (7%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y++  + T EA ++DP    +  LK   ++G+++              G  +   ER   
Sbjct: 16  YMVGCQMTGEAIVIDPSRDIEGYLKEAAKEGLHIVATAETHIHADFVSGTREFA-ERFDT 74

Query: 493 IVYGGDD---------RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
             Y  D+               K V    +FK+GN+  + + TP HT  H+ + +   ++
Sbjct: 75  TAYLSDEGDADWKYEFAADIDAKLVTDGNRFKVGNVTFEVMHTPGHTPEHVSFLLYDRDQ 134

Query: 646 GNDSVVFTGDTLFLGGCGR 702
                +FTGD +F+G  GR
Sbjct: 135 TVPMGIFTGDFVFVGDIGR 153


>UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2;
           Synechococcus|Rep: Beta-lactamase-like - Synechococcus
           sp. RS9917
          Length = 370

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 2/142 (1%)
 Frame = +1

Query: 283 KILPALQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           ++  A    + YL+VD  + +  ++DPV    +  L  V E GV+L              
Sbjct: 20  QLFDAETGTFSYLLVDVPSAKGVLIDPVFERHERDLALVRELGVDLVACLDTHAHADHVT 79

Query: 457 GNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636
           G+  + +     I      R   +T+ ++H  +   G   ++   TP HT G + + +  
Sbjct: 80  GSWLMHEATGAAIGLAAAARAENVTQPLQHGDRVGFGARALEVRATPGHTDGCLTFVLD- 138

Query: 637 PEEGNDSVVFTGDTLFLGGCGR 702
               + S  FTGD L + GCGR
Sbjct: 139 ----DASAAFTGDALLIRGCGR 156


>UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1;
           Acinetobacter baumannii ATCC 17978|Rep:
           Beta-lactamase-like protein - Acinetobacter baumannii
           (strain ATCC 17978 / NCDC KC 755)
          Length = 231

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 3/134 (2%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y Y++  + T+ A ++DPV  + +   K +E+    L                 DL++ER
Sbjct: 14  YTYMLGCEETRGAVLIDPVASDIEIYAKELEQHQFTLIYTLDTHVHADHITA-ADLLRER 72

Query: 484 PGL-IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
                V   +  +      +      K+GNL+++  +TP HT     Y V     GN  +
Sbjct: 73  FHCKSVLHRNSEVSCGDILITDGCMLKVGNLSIEARYTPGHTNACTSYLV-----GN--M 125

Query: 661 VFTGDTLFLGGCGR 702
           +FTGD L + GCGR
Sbjct: 126 IFTGDALLIDGCGR 139


>UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4;
           Halobacteriaceae|Rep: Beta-lactamase domain protein -
           Halorubrum lacusprofundi ATCC 49239
          Length = 402

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKT--VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER-P 486
           YL+ D    EAAIVDP+   T   L   EE GV L              G  +L  E   
Sbjct: 150 YLLYDGG--EAAIVDPLRAFTDRYLADAEELGVELTYAFDTHVHADHISGLRNLADEGVE 207

Query: 487 GLIVYGGDDRIGALTKKV---EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657
            ++     DR       V   E   +F +G+  V+ +FTP HTTG   Y +       DS
Sbjct: 208 AMLPAAAADRGVTYADDVTLVEDGDEFTVGDATVETVFTPGHTTGMTSYLL------GDS 261

Query: 658 VVFTGDTLFLGGCGR 702
           ++ TGD LF+    R
Sbjct: 262 LLATGDGLFIESVAR 276


>UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21;
           Actinomycetales|Rep: Beta-lactamase domain protein -
           Mycobacterium sp. (strain KMS)
          Length = 238

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 19/151 (12%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPK-TVLKAVEEQGVNLXXXXXXXXXXXXAGGNE---DL- 471
           N+ YLI D+ T +  +VDP      ++ A+E  G++L             GG+    +L 
Sbjct: 30  NFAYLIGDRETGDCVVVDPAYAAGDLVDALEADGMHLSGVLATHHHPDHVGGSMMGFELK 89

Query: 472 ----IKERPGLIVYGGD------DRIGALTKKV----EHNTKFKIGNLNVQCLFTPCHTT 609
               + ER  + V+          R+  + +      +H     +G ++++ L TP HT 
Sbjct: 90  GLAELLERVSVPVHVNSHEADWVSRVTGIARSELTAHDHGDVVSVGGIDIELLHTPGHTP 149

Query: 610 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           G  C+ +       D  +  GDTLFL GCGR
Sbjct: 150 GSQCFLL-------DGRLVAGDTLFLEGCGR 173


>UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, whole
           genome shotgun sequence; n=5; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_61,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 483

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 1/160 (0%)
 Frame = +1

Query: 226 NQREAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEP-KTVLKAVEEQ 402
           N ++A  S E+   +   V  L      + Y I  ++  EAAI+DP+   +  +K  E +
Sbjct: 12  NTQKAQQSGENFFIQQFQVSCL----GQFSYYI--ESNNEAAIIDPMRDYEDYIKFSESR 65

Query: 403 GVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQ 582
              +              G+ DL K     IV G         K  +      +G   ++
Sbjct: 66  NSVIKYVILTHLHADFVAGHLDLAKITGAQIVLGPQAVTQYQAKIAQDEELLPLGRAYLR 125

Query: 583 CLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            + TP HT    C+ +   ++  D VVF+GD+LFL   GR
Sbjct: 126 VVHTPGHTLESSCFVLVVDDK--DHVVFSGDSLFLEEVGR 163


>UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Predicted
           Zn-dependent hydrolase - Methanosphaera stadtmanae
           (strain DSM 3091)
          Length = 225

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 19/52 (36%), Positives = 33/52 (63%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGG 693
           +E+N   ++GN  ++ L+TP HT+G +CY+     E    ++FTGDT++  G
Sbjct: 119 LENNNVIEVGNWTLKVLYTPGHTSGSVCYY-----EEEKRILFTGDTVYAKG 165


>UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3;
           Deltaproteobacteria|Rep: Beta-lactamase-like - delta
           proteobacterium MLMS-1
          Length = 213

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 23/47 (48%), Positives = 30/47 (63%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +G + +Q + TP HT G IC + TAP       +FTGDTLF+GG GR
Sbjct: 118 LGTIELQVIHTPGHTPGGICLY-TAPH------LFTGDTLFVGGVGR 157


>UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 209

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 11/140 (7%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y+  D ATK  AIVDP  +   +L AV   G+ +             G   +L K  P +
Sbjct: 24  YIFGDDATKMGAIVDPGGDAAGILAAVRGLGLTVSAIFLTHGHYDHVGALPELRKALPDV 83

Query: 493 IVYGGDD----RIGAL------TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642
            VY        R G+L      T      +   +G L V+ +  P HT G +C  V    
Sbjct: 84  PVYLHPAEKAVRDGSLIPDPGPTVDYGDGSTVAVGGLTVEVIHAPGHTPGGVCLKV---- 139

Query: 643 EGNDSVVFTGDTLFLGGCGR 702
                 +FTGDTLF G  GR
Sbjct: 140 ---GDTLFTGDTLFRGSMGR 156


>UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
           Metallo-beta-lactamase superfamily protein -
           Dichelobacter nodosus (strain VCS1703A)
          Length = 235

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 5/138 (3%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAV-EEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           DN+MY+I +    EA +VDP     ++K V  ++ + L                 DL  +
Sbjct: 14  DNFMYIIANGG--EAVVVDPAWNAELVKTVLAQEYLTLTAILLTHAHDDHTNAVSDLYSD 71

Query: 481 RPGLIVYGGDDRIGALTKK----VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
              L +   +  + A        ++   +   G   +Q + TP HT G  C++V      
Sbjct: 72  DVSLFLSADEYPLWANCPVDAVLLQDGDEIFCGADVIQMIATPGHTAGSCCFYV------ 125

Query: 649 NDSVVFTGDTLFLGGCGR 702
            D+ + TGDTLF+ GCGR
Sbjct: 126 -DNNLITGDTLFVYGCGR 142


>UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein;
           n=2; Geobacillus|Rep: Metallo-beta-lactamase family
           protein - Geobacillus thermodenitrificans (strain
           NG80-2)
          Length = 378

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 4/124 (3%)
 Frame = +1

Query: 343 EAAIVDPVEPKTVLKAVEEQ-GVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVY--GGDD 513
           EA +VDP+    V + V +Q GV +              G + L  ER G   Y    + 
Sbjct: 140 EALVVDPLRFIDVYEQVAQQEGVTITHIVDSHLHADHLSGGKALA-ERTGAAYYLMKSEG 198

Query: 514 RIGALTKKVEHNT-KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLG 690
            +       +H T  F+  +L V  + TP HT G + +FV      N   +F+GDT+F+G
Sbjct: 199 AVFDFEPLEQHETIDFENVHLEVLAVKTPGHTPGSVSFFV------NGKWLFSGDTIFVG 252

Query: 691 GCGR 702
           G GR
Sbjct: 253 GLGR 256


>UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 279

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 2/133 (1%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y YL+ D    +A I+DPV  + K   + V++ G  L              G+  L K  
Sbjct: 61  YSYLLADLKNGQAVIIDPVLEQAKRDAQLVKDLGFELKYAINTHMHADHITGSGWLRKLT 120

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
               V        A  + +    +   G   +  L TP HT G + Y +      +   V
Sbjct: 121 GCQSVIAAASGAKA-DRHLNEGDRIDFGTHVIDALATPGHTNGCMTYVIK-----DQGCV 174

Query: 664 FTGDTLFLGGCGR 702
           FTGDTL + GCGR
Sbjct: 175 FTGDTLLIRGCGR 187


>UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1;
           Planctomyces maris DSM 8797|Rep: Putative
           uncharacterized protein - Planctomyces maris DSM 8797
          Length = 471

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 9/138 (6%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL---IKER 483
           YLI D+ T EA ++DP  +    +    E  +++              G+ +L   + ++
Sbjct: 16  YLIGDEKTGEAVVIDPTRDVDDFIDYAREHDLHIRHIIETHIHADFVCGSRELKTRLDDQ 75

Query: 484 PGLIV--YGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH--ICYFVTAPEEG 648
           P +    YGG D       ++V+ +   ++G+L ++    P HT  H  +  F  +  E 
Sbjct: 76  PLIYCSSYGGADWNQSFADRQVKESDSIQMGDLKLEFRHVPGHTPEHLAVLLFDQSRSET 135

Query: 649 NDSVVFTGDTLFLGGCGR 702
           +   +FTGD LF+G  GR
Sbjct: 136 SPWCMFTGDFLFVGDVGR 153


>UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 214

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 20/151 (13%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIK--- 477
           + YL+ D+ + E  ++DP  +   +++ ++E+GV L              GN  +I    
Sbjct: 14  FCYLVYDEVSGEGILIDPAGDEDGLIQLLKEKGVKLRYVVNTHGHPDHTCGNGKIIDATG 73

Query: 478 -------------ERP---GLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTT 609
                        +RP   G     G         +VE   +   GNL ++ + TP HT 
Sbjct: 74  AKVVMHTLDDQYFQRPESKGFARMMGFQPAPPADVRVEDGDELTFGNLTMKFINTPGHTP 133

Query: 610 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           G  C  +    +GN   +FTGDTLF+G  GR
Sbjct: 134 GSCCVLI----DGN---LFTGDTLFVGAVGR 157


>UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7;
           Bacteria|Rep: Beta-lactamase-like precursor -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 251

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/56 (41%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-VVFTGDTLFLGGCGR 702
           V+   + + GN+ V  L TP HT   IC  V     G++   V TGDTLF+G  GR
Sbjct: 93  VKDGQRLEAGNVVVDILHTPGHTPDSICLLVRDLRRGDEPWFVITGDTLFVGAAGR 148


>UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein;
           n=1; Plesiocystis pacifica SIR-1|Rep:
           Metallo-beta-lactamase family protein - Plesiocystis
           pacifica SIR-1
          Length = 234

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           DN++Y + DK T+  A+VDP     ++L   E   V +                E L+K 
Sbjct: 17  DNFIYFLGDKRTRSVAVVDPAWHAPSILAEAERLDVTISAILCTHSHFDHVDKVEALLKH 76

Query: 481 RPGLI------VYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAP 639
               +      +   D +   L      +T  ++G  L +  + TP HT G   Y +   
Sbjct: 77  VDVPVHMLRPEIEFADFKCENLIASSPGDT-VRVGEQLEITMMHTPGHTPGSCSYRL--- 132

Query: 640 EEGNDSVVFTGDTLFLGGCGR 702
               DS+V TGDTLF+ GCGR
Sbjct: 133 ---RDSIV-TGDTLFVNGCGR 149


>UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1;
           Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like
           protein - Lentisphaera araneosa HTCC2155
          Length = 213

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 20/142 (14%)
 Frame = +1

Query: 337 TKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDD 513
           +KEA ++DP  E +T+LK +  QG+ +             G   ++ +     +    DD
Sbjct: 25  SKEAILIDPGSEAETILKKINYQGLKIKAIIHTHAHLDHFGATHEVSESTDASVHLHKDD 84

Query: 514 ----RIGALTKK---------------VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636
                I  L  +               +E +  F+ G   ++ + TP H+ G  C+ +  
Sbjct: 85  MPLWNIADLQAEMLGLPKCPHANVDHFIEDSQSFEFGEFKLEAIHTPGHSAGSTCFKI-- 142

Query: 637 PEEGNDSVVFTGDTLFLGGCGR 702
            E  ++ ++F+GDTLF  G GR
Sbjct: 143 -ENSDEQLLFSGDTLFRRGVGR 163


>UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2;
           Chloroflexus|Rep: Beta-lactamase-like - Chloroflexus
           aggregans DSM 9485
          Length = 395

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 20/50 (40%), Positives = 29/50 (58%)
 Frame = +1

Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +  +G+L ++  + P HT GH+ Y V AP    +  + TGD L L GCGR
Sbjct: 228 RLPLGHLLIEAHWFPGHTPGHLVYRVIAP--NGERYLLTGDALLLSGCGR 275


>UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase related;
           n=4; Thermococcaceae|Rep: Hydroxyacylglutathione
           hydrolase related - Pyrococcus abyssi
          Length = 222

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 22/56 (39%), Positives = 34/56 (60%)
 Frame = +1

Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           K+E   + K+G + ++ + TP HT G  C +    EE  + ++FTGDT+FLG  GR
Sbjct: 123 KLEDGDEIKVGKVKLRLIHTPGHTRGSSCLYY---EE--ERIMFTGDTVFLGTYGR 173


>UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate
           sulfurtransferase/ hydrolase (Probable
           hydroxyacylglutathione hydrolase) 2; n=1; Natronomonas
           pharaonis DSM 2160|Rep: Homolog 4 to thiosulfate
           sulfurtransferase/ hydrolase (Probable
           hydroxyacylglutathione hydrolase) 2 - Natronomonas
           pharaonis (strain DSM 2160 / ATCC 35678)
          Length = 388

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 34/133 (25%), Positives = 55/133 (41%), Gaps = 4/133 (3%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YL+ D     AA VDP       + A  E+G  +              G   L  E    
Sbjct: 139 YLVADPEAGVAAAVDPTRHTDEFVAAAAERGWQIERVLDTHIHADHISGGRQLADELSVP 198

Query: 493 IVYG---GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
              G    D  +G   + +  N    +G+++++ +FTP HT+G   Y V      +++ +
Sbjct: 199 YHLGERVSDRDVGVDYEPLARNEVVTVGDVDLKAVFTPGHTSGMASYLV------DENAL 252

Query: 664 FTGDTLFLGGCGR 702
            TGDT+F+   GR
Sbjct: 253 LTGDTVFVDSVGR 265


>UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrolase;
           n=2; Candidatus Blochmannia|Rep: Probable
           hydroxyacylglutathione hydrolase - Blochmannia
           floridanus
          Length = 256

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 2/137 (1%)
 Frame = +1

Query: 295 ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474
           +LQ NY+++I +   ++  I+DP E   V+K +    +                G   LI
Sbjct: 8   SLQTNYIWIIYNHI-RQCIIIDPGESLKVIKMLNHLQLIPEAILLTHNHRDHTNGVFTLI 66

Query: 475 KERPGLIVYGGDDRIGA--LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
           +  P + +YG  +       T  V      +I N  ++ L  P HT  HI ++       
Sbjct: 67  QHFPKIKIYGPIETQNQNFATITVSEGDTLQILNQEIKVLNFPGHTPHHIGFYYK----- 121

Query: 649 NDSVVFTGDTLFLGGCG 699
             S +F+GDT+F  GCG
Sbjct: 122 --SWLFSGDTIFSAGCG 136


>UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: Beta-lactamase domain protein - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 236

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 3/138 (2%)
 Frame = +1

Query: 298 LQDNYMYLIVDKATKEAAIVDPVEP--KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL 471
           +   Y YL+ D  T +A I+D V+   +  +  +EE  + L               +  L
Sbjct: 12  ISSTYTYLLADMQTFDAIIIDAVDETKQRDIDLIEELNLKLKYILETHVHADHITSSCSL 71

Query: 472 IKE-RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648
            +      IV G  + I      +  N     G+  +  + TP HT G + Y V      
Sbjct: 72  KQHFMQAKIVLGSANIITCADILLNDNDTLSFGDYTLSAMATPGHTDGCMSYVV------ 125

Query: 649 NDSVVFTGDTLFLGGCGR 702
            ++ +FTGDTL +  CGR
Sbjct: 126 -NNQIFTGDTLLIRSCGR 142


>UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like
           domain protein; n=7; Bacteria|Rep:
           Metallo-beta-lactamase/rhodanese-like domain protein -
           Gramella forsetii (strain KT0803)
          Length = 476

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 5/134 (3%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG- 489
           Y I D++   AAI+DP     + L+   + GV                G   L     G 
Sbjct: 24  YFICDESAGGAAIIDPRPDADIYLQKARQYGVTFTHVFETHIHADFMSGARQLKARCKGS 83

Query: 490 ---LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
               +   GD       + V    +F+ G + +    TP HT  H+ Y +    + +   
Sbjct: 84  AKIFVSIEGDATYDFAYEPVREGDEFEFGQVKMMAKHTPGHTPEHLSYLLYESHKEDPWG 143

Query: 661 VFTGDTLFLGGCGR 702
           + TGD+LF+   GR
Sbjct: 144 IVTGDSLFVDSLGR 157


>UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|Rep:
           Bll1007 protein - Bradyrhizobium japonicum
          Length = 345

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 2/142 (1%)
 Frame = +1

Query: 283 KILPALQDNYMYLIVDKATKEAAIVDPVEPKT--VLKAVEEQGVNLXXXXXXXXXXXXAG 456
           ++  ++   Y Y++  +   EA I+DPV  K     + + E  + L              
Sbjct: 5   QLFDSVSGTYSYVLASRHGGEALILDPVLEKVDRYCQLLRELDLKLVKAVDTHLHADHVT 64

Query: 457 GNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636
           G  +L      + V G   +   +  +V    K  I  L++  ++TP HT     Y +  
Sbjct: 65  GLGELRDRTHCMTVMGDQTKADVVAMRVADGDKVTIEGLSLDVMYTPGHTDDSYSYLM-- 122

Query: 637 PEEGNDSVVFTGDTLFLGGCGR 702
                   VFTGDTL + G GR
Sbjct: 123 -----GDRVFTGDTLLIRGTGR 139


>UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein;
           n=17; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Burkholderia mallei (Pseudomonas mallei)
          Length = 246

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 2/131 (1%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YL+         +VD V EP T L+A  + G+ +                  L       
Sbjct: 16  YLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAA 75

Query: 493 IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-VVFT 669
            V      +    K VE   + ++GN+ ++ L TP HT  HI   VT      +  +  T
Sbjct: 76  YVLSTKADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALT 135

Query: 670 GDTLFLGGCGR 702
           G TL +G  GR
Sbjct: 136 GHTLMIGDLGR 146


>UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16;
           Proteobacteria|Rep: Beta-lactamase-like - Burkholderia
           sp. (strain 383) (Burkholderia cepacia (strain ATCC
           17760/ NCIB 9086 / R18194))
          Length = 356

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 3/134 (2%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y YL+ D+A++EA ++DPV  + +     ++E G+ L              G   L+K+R
Sbjct: 14  YTYLLADRASREAVLIDPVFEQVRRDAALLDELGLRLVATVDTHVHADHVTG-AWLLKQR 72

Query: 484 PG-LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
            G  I            + +    +   G   +    TP HT+G  C  +   +E   S+
Sbjct: 73  TGSTIAISAASGAQGADRYLNDGDRCAFGARYLTVRATPGHTSG--CISLVLDDE---SM 127

Query: 661 VFTGDTLFLGGCGR 702
            FTGD L + G GR
Sbjct: 128 AFTGDCLLIRGTGR 141


>UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Putative
           uncharacterized protein - Candidatus Kuenenia
           stuttgartiensis
          Length = 461

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 4/133 (3%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y+I   A K AA++DP  E +  L     QG+ +              GN + I  R G 
Sbjct: 16  YVIGCPAAKVAAVIDPKREIQEYLDITRNQGMKITHVIETHIHADHISGNLE-ITARTGA 74

Query: 493 IVYGGDDRIGALTKK-VEHNTKFKIGNLNVQCLFTPCHTTGHICYFV--TAPEEGNDSVV 663
            +Y  +    A   K ++     ++G   ++ L TP HT   I   V  T+  E     +
Sbjct: 75  DIYFYEKAPVAFKHKTLKEGDTIELGTAILEVLHTPGHTPHSISLLVKDTSRSEEEPWFM 134

Query: 664 FTGDTLFLGGCGR 702
            TGD LF+G  GR
Sbjct: 135 LTGDLLFVGDVGR 147


>UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase
           domain protein - Victivallis vadensis ATCC BAA-548
          Length = 205

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 2/133 (1%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQG-VNLXXXXXXXXXXXXAGGNEDLIKE 480
           N+ YL V  A  +A +VDP  + + + +AVE  G +                   + +  
Sbjct: 16  NFSYLAV-AANGDALLVDPTGDAEVICRAVEAAGSITPRYILLTHGHLDHTQAVGEALGF 74

Query: 481 RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
            P  +V   +  +   T+ +        G   V+ +FTP HT   +CY        +DS 
Sbjct: 75  FPAEVVAHPNHPLAGRTR-LRDGQLLPFGETAVEAIFTPGHTRDSVCY-----RFADDSA 128

Query: 661 VFTGDTLFLGGCG 699
           VFTGD LF+G  G
Sbjct: 129 VFTGDVLFVGCIG 141


>UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 226

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 8/148 (5%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456
           V++   L  N+  +I    TK AA+VDP  E   +L A  E+G  +              
Sbjct: 13  VQLEVGLLQNFCEVIGCPQTKRAALVDPAFEVDRLLAAASERGWTVDTILLTHTHDDHVA 72

Query: 457 GNEDLIKE-------RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH 615
           G ++   E        P  +         A    V       IG+  ++ ++ P HT G 
Sbjct: 73  GLDEAFSETGATLRCHPAEVEVASAFVDRAKIVPVADGEDVAIGDGRMRAVYAPGHTPGC 132

Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           +C++   PE      + TGD LF+G CG
Sbjct: 133 VCWY--GPEA---KALITGDVLFVGSCG 155


>UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20;
           Pasteurellaceae|Rep: Uncharacterized protein HI1663 -
           Haemophilus influenzae
          Length = 212

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 47/168 (27%), Positives = 74/168 (44%), Gaps = 25/168 (14%)
 Frame = +1

Query: 274 MDVKILP--ALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXX 444
           M+++I+P  A Q N   +  D+  K AAI+DP  E + +++ +EE  +NL          
Sbjct: 1   MNIEIIPVTAFQQNCSLIWDDE--KNAAIIDPGGEAERLIQRIEELDLNLKVLLLTHGHL 58

Query: 445 XXAGGNEDLIKERPGLIVYGGDDRIGALTKKV-EHNTKFKIGNL---------------- 573
              G    L K+  G+ ++G +++   L + + E   +F + N+                
Sbjct: 59  DHVGAAMQL-KQHFGVEIWGSNEKDKFLFESLPEQAQRFGLPNIDAFLPDRWFNQEGEIL 117

Query: 574 -----NVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
                N + L  P HT GHI +      E    V FTGD LF GG GR
Sbjct: 118 KLDGFNFEILHLPGHTPGHIGFI-----EHEKKVAFTGDVLFQGGIGR 160


>UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including
           glyoxylases; n=2; Thermoanaerobacter|Rep: Zn-dependent
           hydrolases, including glyoxylases - Thermoanaerobacter
           tengcongensis
          Length = 214

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 20/150 (13%)
 Frame = +1

Query: 313 MYLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG 489
           +Y++ D+ T+E  I+DP E    +K  ++E G+ +             GG E++     G
Sbjct: 20  LYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLTHGHFDHIGGVEEIRAFTGG 79

Query: 490 LIVYGGDDRIGALT----------KKV---------EHNTKFKIGNLNVQCLFTPCHTTG 612
            +    +D    L           KKV         +       GN  V+ + TP HT G
Sbjct: 80  KVAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDVLGFGNYYVEVISTPGHTKG 139

Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            +C+ +         V FTGDTLF G  GR
Sbjct: 140 SVCFKI-------GDVYFTGDTLFRGSIGR 162


>UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia
           glossinidia endosymbiont of Glossina brevipalpis|Rep:
           GloB protein - Wigglesworthia glossinidia brevipalpis
          Length = 251

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 1/137 (0%)
 Frame = +1

Query: 301 QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           +DNY++L+ +   K   IVDP E  ++    +++ +                G E L K 
Sbjct: 10  EDNYIWLLYNN-DKNCIIVDPGEFISIHNICKKKKLTPVAIFLTHHHHDHVDGVESL-KT 67

Query: 481 RPGLIVYGGDDRIG-ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657
                VYG  + I    TK V+   +  + N   +    P HT GH+ ++       +  
Sbjct: 68  YFNTPVYGPKETIKYGTTKIVKEGDEIFLLNKCFKVFELPGHTLGHVGFY-------SPP 120

Query: 658 VVFTGDTLFLGGCGRFF 708
             F GDTLF  GCGR F
Sbjct: 121 WFFCGDTLFSAGCGRLF 137


>UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           Beta-lactamase-like protein - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 214

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 20/154 (12%)
 Frame = +1

Query: 301 QDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG------ 459
           Q+N  Y++ D+A+   A+VDP  E   +  AVE+ G+ +             G       
Sbjct: 12  QEN-CYILGDEASGSGALVDPGDEAVRIALAVEQTGLEIEKILLTHAHIDHVGAVASLVE 70

Query: 460 -----------NEDLIKERPGLIVYGG--DDRIGALTKKVEHNTKFKIGNLNVQCLFTPC 600
                      +E L+++ P   +  G    ++  L   +E   + ++G L ++ L+TP 
Sbjct: 71  EYGCPVLAHRESEPLLEQLPTQALMMGLRFGKVPRLDGYIEDRERVEVGGLTLEALYTPG 130

Query: 601 HTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           H  GH+ +++      ++  + +GD LF G  GR
Sbjct: 131 HAPGHLAFYLE-----SEGALLSGDALFAGSVGR 159


>UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2;
           Roseiflexus|Rep: Beta-lactamase domain protein -
           Roseiflexus sp. RS-1
          Length = 489

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 38/140 (27%), Positives = 57/140 (40%), Gaps = 11/140 (7%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YLI    + E AIVDP + P+  L A  ++G+ +                  L      L
Sbjct: 16  YLIGCIQSGECAIVDPGLPPEEYLVAAADRGLRITAIIETHFHADYFSTGRALAALTGAL 75

Query: 493 IVYGGDDRI-----GALTK----KVEHNTKFKIGNLNVQCLFTPCHTTGHICY-FVTAPE 642
           I     D I     GA       +V    + +IGN+ ++ + TP HT  H+ Y  +  P 
Sbjct: 76  IYAPSRDDIENDITGASVHYPHTRVRDGDEIRIGNIIIRAIHTPGHTPEHMAYAVIDTPR 135

Query: 643 EGNDSVVFTGDTLFLGGCGR 702
                +V TGD+LF+    R
Sbjct: 136 ASEPWMVLTGDSLFINDVAR 155


>UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1;
           Collinsella aerofaciens ATCC 25986|Rep: Putative
           uncharacterized protein - Collinsella aerofaciens ATCC
           25986
          Length = 229

 Score = 42.7 bits (96), Expect = 0.009
 Identities = 24/61 (39%), Positives = 34/61 (55%)
 Frame = +1

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           G  T+ +      ++G++ +Q + TP HT G I  F  A E+GN  + F GDTLF G  G
Sbjct: 122 GEPTRLLAEGDTIELGDICLQVIETPGHTPGGIVLFA-ATEQGN--IAFVGDTLFPGSHG 178

Query: 700 R 702
           R
Sbjct: 179 R 179


>UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas sp.
           JS666|Rep: Beta-lactamase-like - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 346

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 22/56 (39%), Positives = 29/56 (51%)
 Frame = +1

Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +V+      +G L +Q L+TP HT   +C          D  VFTGDTL +GG GR
Sbjct: 89  RVDDGEMIVLGKLRLQVLYTPGHTVDSMCLVA-------DDRVFTGDTLLIGGTGR 137


>UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein;
           n=8; Clostridium|Rep: Metallo-beta-lactamase family
           protein - Clostridium perfringens (strain SM101 / Type
           A)
          Length = 206

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 16/159 (10%)
 Frame = +1

Query: 274 MDVKILPA-LQDNYMYLIVDKATKEAAIVDPVEPKTVLK-AVEEQGVNLXXXXXXXXXXX 447
           M +K +P  +     Y+++D+ TK+  IVDP E  + ++  +E                 
Sbjct: 1   MLIKTIPVGMYQANCYVVIDEETKDCIIVDPGEEASRIENVIESLDAKPKMILLTHGHFD 60

Query: 448 XAGGNEDLIKER--PGLIVYGGDDRI-------GALTK-----KVEHNTKFKIGNLNVQC 585
             G  + L ++   P  I    +D I       G L K     K     KF   N  ++C
Sbjct: 61  HVGAVQKLAEKYKIPFYIDKKDEDMIERNVDVFGKLPKADGYLKDGDTLKFS-DNYEIKC 119

Query: 586 LFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           L TP HT G +C+ +       D+ +FTGDTLF    GR
Sbjct: 120 LETPGHTPGGLCFLI-------DNCLFTGDTLFRESIGR 151


>UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain
           protein - Solibacter usitatus (strain Ellin6076)
          Length = 465

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 2/121 (1%)
 Frame = +1

Query: 346 AAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIG 522
           AA+VDP     + ++   + G+ +              G+++L       I  G +    
Sbjct: 24  AAVVDPQRDVGIYIEDAVKHGLRIAHVVETHLHADFISGHQELATLTGADIYLGAEAGAA 83

Query: 523 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-VVFTGDTLFLGGCG 699
                V    + + GN  ++ L TP HT   I   VT  E   D   V TGDTLF+G  G
Sbjct: 84  FPHVPVRDGDELRFGNCVLRFLETPGHTLESISILVTDLERSPDPYAVLTGDTLFIGDVG 143

Query: 700 R 702
           R
Sbjct: 144 R 144


>UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep:
           Orf c06001 protein - Sulfolobus solfataricus
          Length = 247

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 4/61 (6%)
 Frame = +1

Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV---TAPEEGNDS-VVFTGDTLFLGGCG 699
           ++V++  + K GN+ ++ L TP HT   I   +      E  N+   + TGDTLF+GG G
Sbjct: 92  ERVKNGEEIKAGNVKIKVLHTPGHTPDSISVLIYDRRRDESWNEPWAILTGDTLFVGGLG 151

Query: 700 R 702
           R
Sbjct: 152 R 152


>UniRef50_Q81Q95 Cluster: Metallo-beta-lactamase/rhodanese-like
           domain protein; n=12; Bacillaceae|Rep:
           Metallo-beta-lactamase/rhodanese-like domain protein -
           Bacillus anthracis
          Length = 484

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-----VVFTGDTLFLGGCGR 702
           V   T+FK+G++    + TP HT   I + VT   + N +      +FTGD +F+G  GR
Sbjct: 99  VREGTEFKVGHIKFNVIHTPGHTPESISFLVTDTSQNNYTNDKPIGIFTGDFIFVGDIGR 158


>UniRef50_Q1AUZ4 Cluster: Beta-lactamase-like protein; n=1;
           Rubrobacter xylanophilus DSM 9941|Rep:
           Beta-lactamase-like protein - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 457

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 32/122 (26%), Positives = 49/122 (40%), Gaps = 2/122 (1%)
 Frame = +1

Query: 343 EAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519
           EAA+VDP  E +  L+  EE G ++              G   L +     I    D  +
Sbjct: 23  EAAVVDPKWEIEEYLRIAEENGFDIAHILETHNHADHVSGKGRLAEATGAKIHISKDAGV 82

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT-APEEGNDSVVFTGDTLFLGGC 696
               + +      ++G + +  L TP H   H+ + V      G+  VV TGD LF+G  
Sbjct: 83  EYDHEPLSDGDVVEVGGVRLVALSTPGHRPEHMSFLVEDTSRSGSPWVVLTGDFLFVGDL 142

Query: 697 GR 702
            R
Sbjct: 143 AR 144


>UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3;
           Cystobacterineae|Rep: Myofibrillogenesis regulator 1 -
           Stigmatella aurantiaca DW4/3-1
          Length = 220

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 10/143 (6%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           DN++YL+      E  +VDP  +   + +A+ E G  L              G  +L+  
Sbjct: 17  DNFVYLVGAADAPEVLVVDPAWDVPAIERAMAEDGKRLVGAFVSHCHKDHINGLPELLS- 75

Query: 481 RPGLIVYGGDDRI---------GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633
           R  + VY   + +         G   + V       +G      L TP HT G  C    
Sbjct: 76  RHDVPVYAQREEVAFSEDLRALGGALRPVGPGEALTVGPRTFLALHTPGHTPGSHCLLA- 134

Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702
                 D++V +GDT+F+ GCGR
Sbjct: 135 -----GDALV-SGDTVFINGCGR 151


>UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus torques ATCC 27756
          Length = 207

 Score = 41.9 bits (94), Expect = 0.015
 Identities = 21/66 (31%), Positives = 34/66 (51%)
 Frame = +1

Query: 505 GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684
           G   +    + V+ +T+ +     V+ + TP HT G  CY++     G + V+F+GDTLF
Sbjct: 99  GQSYVFTKAEYVKADTQIETAGFQVEIIPTPGHTEGGCCYYI-----GEEHVLFSGDTLF 153

Query: 685 LGGCGR 702
               GR
Sbjct: 154 HNSIGR 159


>UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione
           hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep:
           Similar to hydroxyacylglutathione hydrolase - Candidatus
           Kuenenia stuttgartiensis
          Length = 189

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 30/129 (23%), Positives = 54/129 (41%), Gaps = 1/129 (0%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YL+ D  T+    +DP      ++A + E+ + L              G ++  +  P +
Sbjct: 20  YLVADPETRVGVFIDPGGFSDEIEAFIRERQILLQYLFFTHGHWDHTEGMQEFSRRYP-V 78

Query: 493 IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 672
             Y G+  + +    ++ +   ++G L  + L TP HT   + Y++          VFTG
Sbjct: 79  KSYAGEGEVHSANNILQGSEIIEVGALQFKALSTPGHTLHGMSYYIPGG-------VFTG 131

Query: 673 DTLFLGGCG 699
           D LF G  G
Sbjct: 132 DALFCGSVG 140


>UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1;
           Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase
           domain protein - Alkaliphilus metalliredigens QYMF
          Length = 207

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 20/55 (36%), Positives = 29/55 (52%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           + H     +G L ++ + TP HT G IC  V      ++ V+FTGDT+F    GR
Sbjct: 110 LSHGDTISVGALQLEVIHTPGHTPGSICLAVK-----DEKVIFTGDTVFSDALGR 159


>UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1;
           Marinobacter aquaeolei VT8|Rep: Beta-lactamase domain
           protein - Marinobacter aquaeolei (strain ATCC 700491 /
           DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus
           (strain DSM 11845))
          Length = 186

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 2/132 (1%)
 Frame = +1

Query: 298 LQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL 471
           +   Y YL+  + T  A ++DPV    +  L  V + G+ L                 +L
Sbjct: 10  VSSTYTYLLGCEETGRAVLIDPVINSVERDLAEVSKLGLKLEYTLDTHIHADHITSAREL 69

Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651
            ++    I     D +      VE    F++G L+ Q + TP HT GH  Y +       
Sbjct: 70  KQKAGSKIAAPAMDCLPCTDVGVEEGRPFQVGRLSFQPIHTPGHTDGHFAYRL------- 122

Query: 652 DSVVFTGDTLFL 687
           D  +FT D L +
Sbjct: 123 DDRIFTDDALLI 134


>UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;
           n=36; cellular organisms|Rep: ETHE1 protein,
           mitochondrial precursor - Homo sapiens (Human)
          Length = 254

 Score = 41.5 bits (93), Expect = 0.020
 Identities = 32/133 (24%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPVEPKTVLKA--VEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           + YL+ D+ ++EA ++DPV       A  ++E G+ L              G+  L    
Sbjct: 36  FTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLL 95

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
           PG                +E     + G   ++   +P HT G + + +      + S+ 
Sbjct: 96  PGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLN-----DHSMA 150

Query: 664 FTGDTLFLGGCGR 702
           FTGD L + GCGR
Sbjct: 151 FTGDALLIRGCGR 163


>UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Anaeromyxobacter|Rep: Hydroxyacylglutathione hydrolase -
           Anaeromyxobacter sp. Fw109-5
          Length = 255

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 2/135 (1%)
 Frame = +1

Query: 301 QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480
           +DNY+YL+ +   +++ +VDP +    L    +  V              +GG+ + ++ 
Sbjct: 10  RDNYVYLLAEG--EDSVLVDPGDAAVALALAADHAVRPRFVLHTHGHLDHSGGSAE-VRA 66

Query: 481 RPGLIVYG--GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND 654
             G  V G   D    A  + V  +    +G L V     P HT G + +          
Sbjct: 67  ALGAEVLGHAADAAWFAPDRDVAGHRTLALGALRVAVHEVPGHTPGSVLFAWRGK----- 121

Query: 655 SVVFTGDTLFLGGCG 699
             + TGDTLF GGCG
Sbjct: 122 --LLTGDTLFWGGCG 134


>UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep:
           Hydrolase - Parvularcula bermudensis HTCC2503
          Length = 451

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 5/128 (3%)
 Frame = +1

Query: 334 ATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGD 510
           A  EAA++DP     + L    E+G  +              G   ++KE  G  V+ G 
Sbjct: 20  ADGEAAVIDPRRDIDIYLDLAREEGSVIKHVFETHRNEDLLSG-APVLKEETGAKVWHGP 78

Query: 511 DRIGALTKKVE--HNTKFKIGNLNVQCLFTPCHTTGHICYFV--TAPEEGNDSVVFTGDT 678
           +    +    E      F+IG   ++ L TP HT   + Y +   + EEG   V FTGD 
Sbjct: 79  NPEKPIQYAAETREGDTFEIGGALLKVLETPGHTEDSLSYVLYDKSFEEGPVGV-FTGDA 137

Query: 679 LFLGGCGR 702
           LF+G  GR
Sbjct: 138 LFIGDVGR 145


>UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 518

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
 Frame = +1

Query: 565 GNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV------VFTGDTLFLGGCGRFF 708
           G   VQ +  P HT G + + V + EEG  +       VFTGD+LF GGCG  F
Sbjct: 291 GAAKVQAMAAPGHTKGSLVFVVGSAEEGVLTATPARVAVFTGDSLFCGGCGAPF 344



 Score = 40.3 bits (90), Expect = 0.046
 Identities = 17/36 (47%), Positives = 23/36 (63%)
 Frame = +1

Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE 396
           +P   DNY YLIV   T + A VDP +P+ VL+ +E
Sbjct: 165 IPIFGDNYAYLIVSMQTHKVAAVDPADPEMVLRIME 200


>UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10;
           Bacillaceae|Rep: Uncharacterized protein yqgX - Bacillus
           subtilis
          Length = 211

 Score = 41.1 bits (92), Expect = 0.027
 Identities = 20/55 (36%), Positives = 32/55 (58%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +E + +  IG  +++ LFTP H+ G + Y+V      +  +V +GD LF GG GR
Sbjct: 109 IEGDGELNIGPFHLETLFTPGHSPGSVSYYVK-----DADLVISGDVLFQGGIGR 158


>UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 209

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 20/48 (41%), Positives = 30/48 (62%)
 Frame = +1

Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           ++   +VQ + TP HT G  CY++   +EG   V+F+GDT+F G  GR
Sbjct: 119 ELAGFSVQMIETPGHTLGSCCYYL--KDEG---VLFSGDTVFCGSVGR 161


>UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor;
           n=5; Desulfuromonadales|Rep: Beta-lactamase domain
           protein precursor - Geobacter uraniumreducens Rf4
          Length = 251

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 20/149 (13%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG- 489
           +++  + TKE  +VDP  +   VL AV++ G+ +             GGN  L++     
Sbjct: 57  FILGCEETKEGIVVDPGADADRVLAAVKKSGLAIKYVLNTHGHFDHVGGNRRLLEATGAK 116

Query: 490 LIVYGGD--------DRIGALTKKVEHNTK----------FKIGNLNVQCLFTPCHTTGH 615
           L+++  D        +   A   K E++ K             G+  ++ L TP HT G 
Sbjct: 117 LLIHEADVYFLSRAAEVAAAYGLKTENSPKPDGLLEDGMVVIFGSQQLKVLHTPGHTPGG 176

Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            C ++ +  EG    V TGDTLF  G GR
Sbjct: 177 CCLYLES--EGK---VITGDTLFADGVGR 200


>UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;
           n=15; Actinomycetales|Rep: Uncharacterized protein
           Rv2581c/MT2658 - Mycobacterium tuberculosis
          Length = 224

 Score = 40.7 bits (91), Expect = 0.035
 Identities = 19/50 (38%), Positives = 26/50 (52%)
 Frame = +1

Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           K  +G ++V    TP HT G + + V      +  +VFTGDTLF    GR
Sbjct: 122 KIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGR 171


>UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein;
           n=6; Proteobacteria|Rep: Metallo-beta-lactamase family
           protein - Nitrosococcus oceani (strain ATCC 19707 /
           NCIMB 11848)
          Length = 361

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 5/136 (3%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPVEPKT--VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           Y YLI D ATKEA  +DPV  +    L  + +  + L               +  L+++ 
Sbjct: 14  YTYLIGDPATKEAVFIDPVNTRVDEYLNLLNKYNLKLKYSLETHAHADHITAS-GLLRQH 72

Query: 484 PGLIVYGGDDRIGA--LTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGND 654
            G    G     GA     +++       G    ++ L TP HT G I Y         D
Sbjct: 73  TGAKT-GIGQACGAQYADYQLKDGVVLAFGQGEEIKVLATPGHTPGSISYL------WRD 125

Query: 655 SVVFTGDTLFLGGCGR 702
            V FTGD L + GCGR
Sbjct: 126 RV-FTGDALLINGCGR 140


>UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium
           difficile|Rep: Putative hydrolase - Clostridium
           difficile (strain 630)
          Length = 204

 Score = 40.3 bits (90), Expect = 0.046
 Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 21/150 (14%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           Y++ D+ TK+ A++DP       L  V+E  +N+             G  +D IKE+ G 
Sbjct: 16  YVLGDEKTKKCAVIDPGGSLVETLSFVKENELNIEYIILTHGHGDHIGYVKD-IKEKTGA 74

Query: 493 IVYGGDDRIGALTKK--------------------VEHNTKFKIGNLNVQCLFTPCHTTG 612
            V    D    L  K                    V    K ++G L +  L TP HT G
Sbjct: 75  KVVAHVDEKELLNDKNKNLSYTMRCGAQEFDADIYVNDKDKLELGELKMTFLHTPGHTQG 134

Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            +C  V       +  +FTGDTLF G  GR
Sbjct: 135 CMCIRV-------EDEMFTGDTLFAGSIGR 157


>UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n=1;
           unknown|Rep: UPI00015BCB57 UniRef100 entry - unknown
          Length = 217

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 17/55 (30%), Positives = 31/55 (56%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           ++   K  I +++++ + TP HT G  C+++      + + +  GDTLF GG GR
Sbjct: 116 IKDGDKLSIASVDIEIIHTPGHTPGGCCFYLP-----SQNTLIAGDTLFKGGVGR 165


>UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrolase;
           n=1; Vibrio vulnificus YJ016|Rep: Putative
           hydroxyacylglutathione hydrolase - Vibrio vulnificus
           (strain YJ016)
          Length = 247

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 1/137 (0%)
 Frame = +1

Query: 295 ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474
           +L DNY++++ DK+  +A ++DP E + ++  +++  + L              G   L 
Sbjct: 10  SLIDNYIWILFDKS--KAIVIDPGESEKIINFLDKNNLTLEFIFLTHGHCDHTKGVFSLK 67

Query: 475 KERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651
           ++ P   ++      +G     ++   +  + N     L  P HT  HI           
Sbjct: 68  EKFPNASLFVPIGLELGLGESIIKEGDELNLLNSTFNVLELPGHTDNHIGIMY------K 121

Query: 652 DSVVFTGDTLFLGGCGR 702
           D++ F GD LF  GCGR
Sbjct: 122 DNL-FCGDVLFSAGCGR 137


>UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1;
           Syntrophus aciditrophicus SB|Rep: Hydroxyacylglutathione
           hydrolase W - Syntrophus aciditrophicus (strain SB)
          Length = 257

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 19/150 (12%)
 Frame = +1

Query: 310 YMYLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           + YL+ D  T +A ++DP +    +L   E+  + +              GN ++     
Sbjct: 62  FAYLVGDSETGDALVIDPADNIDGILATAEKNNLRIKYIVNTHGHIDHISGNREMKSRTD 121

Query: 487 G-LIVYGGDDRIGALTKK-----------------VEHNTKFKIGNLNVQCLFTPCHTTG 612
             +I++ GD R+   T                   V+      +G ++++ + TP H+ G
Sbjct: 122 APIIIHEGDARMLGNTSPMLLHMFGAEDSPPADMTVKDGDTITVGKISLKVIHTPGHSPG 181

Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            +C ++          VFTGDTLF+   GR
Sbjct: 182 GMCLYIKG-------FVFTGDTLFVESVGR 204


>UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11;
           Gammaproteobacteria|Rep: Beta-lactamase domain protein -
           Enterobacter sp. 638
          Length = 215

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +GN+ +Q L  P HT GHI +F     +    ++ +GD +F GG GR
Sbjct: 119 VGNVTLQILHCPGHTPGHIVFF-----DDQSRLLISGDVIFKGGVGR 160


>UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein;
           n=2; Corynebacterineae|Rep: Metallo-beta-lactamase
           family protein - Mycobacterium smegmatis (strain ATCC
           700084 / mc(2)155)
          Length = 210

 Score = 39.9 bits (89), Expect = 0.061
 Identities = 22/56 (39%), Positives = 30/56 (53%)
 Frame = +1

Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           + VE     K G + V  L TP H+ G +C+ +  PE    + V +GDTLF GG G
Sbjct: 106 RAVEDGLVLKAGEIEVHALHTPGHSPGSVCWSI--PEL---NAVISGDTLFQGGPG 156


>UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120;
           Bacteria|Rep: Uncharacterized protein ycbL - Escherichia
           coli (strain K12)
          Length = 215

 Score = 39.5 bits (88), Expect = 0.081
 Identities = 18/47 (38%), Positives = 27/47 (57%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           IGN+ +Q L  P HT GH+ +F     +    ++ +GD +F GG GR
Sbjct: 119 IGNVTLQVLHCPGHTPGHVVFF-----DDRAKLLISGDVIFKGGVGR 160


>UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep:
           Beta-lactamase-like - Moorella thermoacetica (strain
           ATCC 39073)
          Length = 207

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 41/151 (27%), Positives = 59/151 (39%), Gaps = 22/151 (14%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492
           YLI    T E A++DP  E + +L A  E G+N+             G N   IK   G 
Sbjct: 16  YLIGCPETGEGAVIDPGAEGERILAAAREAGLNIKQIINTHGHGDHIGAN-GAIKAATGA 74

Query: 493 --------------------IVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTT 609
                               ++ G  +      + +E +    IG  + ++ + TP HT 
Sbjct: 75  AILIHRADAHYLTDPGRNLSVLLGSREASPPADRLLEEDDTIAIGKTVTLRVIHTPGHTP 134

Query: 610 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           G IC          + +VFTGDTLF G  GR
Sbjct: 135 GGICLH-------GEGLVFTGDTLFAGSIGR 158


>UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Rep:
           Beta-lactamase-like - Desulfitobacterium hafniense
           (strain DCB-2)
          Length = 205

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 21/55 (38%), Positives = 31/55 (56%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +E     ++GNLN+  + TP HT G +C+  +   EG    + +GDTLF G  GR
Sbjct: 109 LEDGQILQVGNLNLTVIATPGHTLGGVCFLTS---EG----LLSGDTLFDGSIGR 156


>UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1;
           Bifidobacterium adolescentis L2-32|Rep: Putative
           uncharacterized protein - Bifidobacterium adolescentis
           L2-32
          Length = 264

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 5/145 (3%)
 Frame = +1

Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXXXXXA- 453
           +++      N  YL+VD  T++A +VDP   +  L+A ++  G  L              
Sbjct: 23  IEVAAGAMKNNNYLVVDPVTRQALLVDPAWQRDKLEAALQRAGATLSAIAITHAHFDHVH 82

Query: 454 -GGNEDLIKERPGLIVYGGDDRIGALTKKVE--HNTKFKIGNLNVQCLFTPCHTTGHICY 624
             G      + P  +     +  G    ++     T   +G L ++ +  P HT G +CY
Sbjct: 83  LAGELSAAHDCPVWMSQCEIETSGFDLPRLLAIDETPRTLGALRIEPILAPGHTPGCLCY 142

Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCG 699
            +          +F GD LF+ GCG
Sbjct: 143 RI-------GGHLFAGDVLFIEGCG 160


>UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2;
           Clostridiaceae|Rep: Beta-lactamase domain protein -
           Alkaliphilus metalliredigens QYMF
          Length = 206

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 21/47 (44%), Positives = 25/47 (53%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           IGNL +  L TP H+ G +C          + VVFTGDTLF    GR
Sbjct: 118 IGNLKLHVLHTPGHSPGGVCI-------RGEGVVFTGDTLFANSIGR 157


>UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 207

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 20/50 (40%), Positives = 30/50 (60%)
 Frame = +1

Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           K  +  +N+  + TP HT G  CY++    E N+ ++F+GDTLF G  GR
Sbjct: 117 KITLAGINMTFIATPGHTPGSGCYYL----EDNE-ILFSGDTLFHGSRGR 161


>UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: YqgX -
           Bacillus sp. B14905
          Length = 214

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 21/55 (38%), Positives = 27/55 (49%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           ++   +F+I N   Q +FTP H+ G I Y        ND     GDTLF  G GR
Sbjct: 114 IKKEQQFEISNFVFQAVFTPGHSPGSISYVFE-----NDGFAIVGDTLFEQGVGR 163


>UniRef50_Q4WA58 Cluster: Metallo-beta-lactamase domain protein;
           n=4; Trichocomaceae|Rep: Metallo-beta-lactamase domain
           protein - Aspergillus fumigatus (Sartorya fumigata)
          Length = 330

 Score = 39.1 bits (87), Expect = 0.11
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
 Frame = +1

Query: 361 PVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLI--VYGGDDRIGALTK 534
           P+    ++  ++   +++             GG  DLI   P L   VY     +G   K
Sbjct: 73  PIWLSRIVGVLQSNNISISHILLTHWHGDHTGGVPDLISYNPTLAEHVYKNLPDLGQ--K 130

Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTL 681
            +E    F +    V+ +FTP H+  H+C+ +   EE N   +FTGD +
Sbjct: 131 PIEDGQIFAVEGATVRAVFTPGHSVDHMCFLL---EEEN--ALFTGDNV 174


>UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2;
           Anaeromyxobacter|Rep: Beta-lactamase domain protein -
           Anaeromyxobacter sp. Fw109-5
          Length = 217

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 20/49 (40%), Positives = 29/49 (59%)
 Frame = +1

Query: 556 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           F++G    + + TP H+ G IC F   P+E    ++F+GDTLF G  GR
Sbjct: 116 FRVGASEGRVIHTPGHSPGSICLFF--PQE---RLLFSGDTLFAGSVGR 159


>UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Reinekea sp. MED297|Rep: Hydroxyacylglutathione
           hydrolase - Reinekea sp. MED297
          Length = 258

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 28/133 (21%), Positives = 50/133 (37%), Gaps = 2/133 (1%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486
           NY +L+    T++AA +DP +   ++   ++  + +              G   L +E  
Sbjct: 14  NYNHLVYCPTTQQAAAIDPFDANHIVDIAKKHSLTIIQIWLTHEHGDHIRGLNSL-RELT 72

Query: 487 GLIVYGGDDRIGALTKKV--EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
           G   +      G     +  E   + ++G   +    TP HT GH  +    P+      
Sbjct: 73  GAKSFAPMTCNGLFESDIWLEDGQEVRLGKETLTHYLTPGHTPGHGVFLYQDPQLSERDF 132

Query: 661 VFTGDTLFLGGCG 699
           +   DTLF  G G
Sbjct: 133 LVCADTLFNAGVG 145


>UniRef50_A4S568 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 476

 Score = 38.7 bits (86), Expect = 0.14
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +1

Query: 115 NFILFKKTYSMLARFVNSLPSGLSQRITKLYFRALIRNQREAHSS-QEDHQYKNMDVKIL 291
           N  L +KTY++ ARF  S  +G  QR   L   A+++   EAH     D +YK+    + 
Sbjct: 236 NLWLRRKTYTLAARFAESKHTGDEQRELNLEMSAMLQYFHEAHHGLYHDVRYKHQPEVVQ 295

Query: 292 PAL-QDNYMYLIVDKATKEAAIVDPV 366
             L +  Y+ ++ D   K+ + + P+
Sbjct: 296 KILFETGYLKVVQDARGKDTSQLAPL 321


>UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37;
           Actinomycetales|Rep: Beta-lactamase-like - Frankia sp.
           (strain CcI3)
          Length = 216

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 20/41 (48%), Positives = 25/41 (60%)
 Frame = +1

Query: 577 VQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           ++ L TP H+ G IC F    E   D V+F+GDTLF GG G
Sbjct: 125 LRVLHTPGHSPGGICLF---GEINGDPVLFSGDTLFRGGPG 162


>UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Saccharophagus degradans 2-40|Rep:
           Hydroxyacylglutathione hydrolase - Saccharophagus
           degradans (strain 2-40 / ATCC 43961 / DSM 17024)
          Length = 272

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 36/153 (23%), Positives = 62/153 (40%), Gaps = 10/153 (6%)
 Frame = +1

Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453
           + V  +P  Q NY++++   +     +VDP     V++ + +  + +             
Sbjct: 9   VSVHPIPIYQGNYVWVMRHTSQNSVVVVDPGSASEVIEYITQHELTIASIIITHSHWDHV 68

Query: 454 GGNEDLIKE----RPGLIVYGGDDRIGALTKKVEHNTKFKIGN----LNVQCLFTPCHTT 609
            G  +L       R    V  G   I  +T  VE   + ++       ++Q + TP H  
Sbjct: 69  TGIAELCANLQLWRDEEPVVYGPSVIQDVTHPVEDGDRIELCKGVDVPSLQVIATPGHMP 128

Query: 610 GHICYFV--TAPEEGNDSVVFTGDTLFLGGCGR 702
            H+ Y +  T P+      +F GDTLF  GCGR
Sbjct: 129 EHLSYLLPLTTPK------LFCGDTLFSCGCGR 155


>UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium
           phytofermentans ISDg|Rep: Beta-lactamase-like -
           Clostridium phytofermentans ISDg
          Length = 216

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 18/50 (36%), Positives = 28/50 (56%)
 Frame = +1

Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           K +  ++    L TP HT G +CY++  P+E    ++ +GDTLF    GR
Sbjct: 117 KIQFADIEFVVLHTPGHTKGSVCYYI--PDE---QILLSGDTLFFESVGR 161


>UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1;
           Fulvimarina pelagi HTCC2506|Rep: Putative
           uncharacterized protein - Fulvimarina pelagi HTCC2506
          Length = 289

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 36/138 (26%), Positives = 58/138 (42%), Gaps = 7/138 (5%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           NY Y++ D +T +A ++DP  E + +L ++    + L                   I   
Sbjct: 38  NYAYIVADFSTGDAVVIDPGWEAEFLLSSLAAFRLRLAGICLTHGHRDHWMA-APAIARA 96

Query: 484 PGLIVYGGD---DRIGALT---KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645
            G  V+      D  G  +   + +E       G++ ++ L TP HT G I Y + A   
Sbjct: 97  TGCPVHMSRLDADHFGFASNGLRPLEAPVALAFGSIGIEALETPGHTAGSISYRIGA--- 153

Query: 646 GNDSVVFTGDTLFLGGCG 699
                +F+GDTLF  GCG
Sbjct: 154 ----CLFSGDTLFSEGCG 167


>UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2;
           Bacteria|Rep: Beta-lactamase domain protein - Pelobacter
           propionicus (strain DSM 2379)
          Length = 253

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 19/55 (34%), Positives = 30/55 (54%)
 Frame = +1

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684
           G  TK ++ N    +GN  +Q L TP H+ GH+C++     E     +FTGD ++
Sbjct: 127 GTPTKVLKDNDVIDMGNRCIQVLHTPGHSPGHMCFW-----EKERGYLFTGDLVY 176


>UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium
           cellulolyticum H10|Rep: Beta-lactamase-like -
           Clostridium cellulolyticum H10
          Length = 208

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 20/55 (36%), Positives = 30/55 (54%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +      K+G L+ + + TP HT G IC  V       ++++F+GDTLF  G GR
Sbjct: 108 LREGNSIKVGELDFKIIHTPGHTCGSICIQV-------ENLLFSGDTLFKFGYGR 155


>UniRef50_Q7QZA0 Cluster: GLP_567_43928_43275; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_567_43928_43275 - Giardia lamblia
           ATCC 50803
          Length = 217

 Score = 38.3 bits (85), Expect = 0.19
 Identities = 20/47 (42%), Positives = 25/47 (53%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           I  + ++ + TP HT G +C    A     D VV TGDTLF  G GR
Sbjct: 128 IDGITLEVIHTPGHTPGSVCLLSDA-----DKVVCTGDTLFANGYGR 169


>UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon
           aurantiacus ATCC 23779|Rep: Beta-lactamase-like -
           Herpetosiphon aurantiacus ATCC 23779
          Length = 369

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 1/121 (0%)
 Frame = +1

Query: 343 EAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519
           +A ++D  ++P   L+  + +G  L               +  L +          + R 
Sbjct: 140 QALVIDASLDPAVYLQLAQARGWQLQAVLDTHIHADHLSRSRQLAELSGATFYLPANQRN 199

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
             + + +  N + ++G   +Q L TP HT   + Y +      + S +F+GDTLFL   G
Sbjct: 200 SGVYQPISANMQIQLGAATIQALATPGHTWESMSYLL------DGSHLFSGDTLFLAAVG 253

Query: 700 R 702
           R
Sbjct: 254 R 254


>UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily
           protein; n=11; Francisella tularensis|Rep:
           Metallo-beta-lactamase superfamily protein - Francisella
           tularensis subsp. tularensis (strain WY96-3418)
          Length = 252

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 30/133 (22%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
 Frame = +1

Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL--IKE 480
           NY YL+ DK+   A ++DP++     + + +  + L              G + L  I  
Sbjct: 14  NYQYLLYDKS--HAIVIDPLKSDIFAEFIAKNKLQLEAILITHKHGDHIAGVKKLLAIYL 71

Query: 481 RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660
              +  Y G+D        V+  +   +G  + + ++ P H   H+C+         +  
Sbjct: 72  NAKVYAYTGNDLFKP-DIYVKDGSFINLGFTSFRVMYIPGHIDDHVCFLFE-----QERA 125

Query: 661 VFTGDTLFLGGCG 699
           +F GDTLF  G G
Sbjct: 126 LFCGDTLFNAGVG 138


>UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1;
           Clostridium thermocellum ATCC 27405|Rep:
           Beta-lactamase-like protein - Clostridium thermocellum
           (strain ATCC 27405 / DSM 1237)
          Length = 201

 Score = 37.9 bits (84), Expect = 0.25
 Identities = 21/47 (44%), Positives = 26/47 (55%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +G L+ + + TP H+ G IC  V         VVFTGDTLF  G GR
Sbjct: 116 VGGLDFEIIHTPGHSAGGICIKV-------GDVVFTGDTLFCMGIGR 155


>UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Methylobacterium extorquens PA1|Rep:
           Hydroxyacylglutathione hydrolase - Methylobacterium
           extorquens PA1
          Length = 158

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 19/47 (40%), Positives = 24/47 (51%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +G L      TP H   H+ Y+       +  VVF+GDTLF  GCGR
Sbjct: 3   VGGLTAAVWETPGHCADHVTYYFA-----DAGVVFSGDTLFTLGCGR 44


>UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 214

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 22/61 (36%), Positives = 31/61 (50%)
 Frame = +1

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           G +   ++      +G L +  + TP HT G  CY+     EG+D +V  GDTLF G  G
Sbjct: 107 GRIDHLLDDGDTVTLGELELTFVATPGHTPGQGCYW-----EGDDIIV--GDTLFAGSVG 159

Query: 700 R 702
           R
Sbjct: 160 R 160


>UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2;
           Bacteria|Rep: Beta-lactamase domain protein -
           Desulfotomaculum reducens MI-1
          Length = 205

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 21/48 (43%), Positives = 28/48 (58%)
 Frame = +1

Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +IGN+ ++ L TP HT G IC      + G D  +F+GDTLF    GR
Sbjct: 117 QIGNITLEVLHTPGHTPGGICL-----KAGKD--LFSGDTLFAQSIGR 157


>UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep:
           Hydroxyacylglutathione hydrolase W - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 220

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           ++H     +G   +  L TP HT G IC ++          +F GDTLF+G  GR
Sbjct: 118 LQHGEAVVLGQTTLTVLHTPGHTPGSICLYMPGH-------LFAGDTLFVGSAGR 165


>UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione
           hydrolase - Dictyostelium discoideum AX4
          Length = 292

 Score = 37.5 bits (83), Expect = 0.33
 Identities = 20/49 (40%), Positives = 29/49 (59%)
 Frame = +1

Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           +F IG+L V+ + TP HT   + Y++      NDS VF GDT+F+   G
Sbjct: 132 RFTIGSLQVRVISTPGHTPACVSYYIE-----NDS-VFVGDTMFMPDVG 174


>UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region family
            protein; n=1; Tetrahymena thermophila SB210|Rep:
            TNFR/NGFR cysteine-rich region family protein -
            Tetrahymena thermophila SB210
          Length = 2129

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 14/32 (43%), Positives = 19/32 (59%)
 Frame = -1

Query: 624  ITYMPSCMTGCKKTLYIQVTDFKLCIVLNFFC 529
            I Y  SC+  C K +Y+  T +K CI  NF+C
Sbjct: 1846 IKYNSSCIVECPKQMYMTQTPYKQCIECNFYC 1877


>UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein;
           n=1; Porphyromonas gingivalis|Rep:
           Metallo-beta-lactamase family protein - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 214

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 18/48 (37%), Positives = 27/48 (56%)
 Frame = +1

Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           ++G   ++ LF P H+ GH+ ++   P+      VFTGD LF G  GR
Sbjct: 123 QLGESIIKVLFVPGHSPGHLAFY--CPQA---QAVFTGDALFAGDMGR 165


>UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1;
           Sphingomonas wittichii RW1|Rep: Hydroxyacylglutathione
           hydrolase - Sphingomonas wittichii RW1
          Length = 256

 Score = 37.1 bits (82), Expect = 0.43
 Identities = 34/134 (25%), Positives = 54/134 (40%), Gaps = 6/134 (4%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLI 495
           YL+    + EAA +DP +   VL+     G+ +            AG N  L +E  G  
Sbjct: 17  YLVWCPDSGEAAAIDPYQLDLVLETARANGLTITRIVNTHEHWDHAGRNAQL-REATGAE 75

Query: 496 VYGGDDRIGALTKKVEH----NTKFKIG-NLNVQCLFTPCHTTGHICYFVTAPEEGNDS- 657
           V       G + + V+H      +  +G +  ++ +  P HT  H+       + G D  
Sbjct: 76  VLAPRAAAGVI-ETVDHMLAEGDEIVVGTSCRLRVIEMPGHTMTHVGLLGEGADRGEDEP 134

Query: 658 VVFTGDTLFLGGCG 699
            +  GDTLF  G G
Sbjct: 135 FLLCGDTLFGAGVG 148


>UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein;
           n=4; Desulfuromonadales|Rep: Metallo-beta-lactamase
           family protein - Geobacter sulfurreducens
          Length = 209

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 20/149 (13%)
 Frame = +1

Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG- 489
           +++  + ++E  IVDP  E   +L+ V E G+ +             GGN  +++     
Sbjct: 16  FILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFDHVGGNRKVLEATGAK 75

Query: 490 LIVYGGD----DRIG--------------ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH 615
           L+V+  D    DR                A    +E      +G L+++ L TP HT G 
Sbjct: 76  LLVHRDDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGTLSLRVLHTPGHTPGG 135

Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
            C  +    EG   V+ TGDTLF    GR
Sbjct: 136 CCLLL----EGEGKVL-TGDTLFEESVGR 159


>UniRef50_Q1VZM6 Cluster: Metallo-beta-lactamase superfamily
           protein; n=10; Bacteroidetes|Rep: Metallo-beta-lactamase
           superfamily protein - Psychroflexus torquis ATCC 700755
          Length = 447

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 3/121 (2%)
 Frame = +1

Query: 349 AIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGA 525
           A+VDP  +P+      EEQ   +               +  + +E  G  +Y     +GA
Sbjct: 25  ALVDPARDPQAYYDYAEEQKAKIVAVFETHPHADFVSSHLQIHQET-GAAIYVSK-LVGA 82

Query: 526 --LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
               +  +   + K+  +  +C+ TP H+   I           +++ FTGDTLF+G  G
Sbjct: 83  DYPHQSFDEGEELKMNGITFKCIHTPGHSPDGITVHAVDKATTKEAI-FTGDTLFIGDVG 141

Query: 700 R 702
           R
Sbjct: 142 R 142


>UniRef50_A1D100 Cluster: FAD binding domain protein; n=4;
           Trichocomaceae|Rep: FAD binding domain protein -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 1100

 Score = 36.7 bits (81), Expect = 0.57
 Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = +1

Query: 208 FRALIRNQREAHSSQEDH--QYKNMDVKILPALQDNYMYLIVDKATKEAA 351
           F A++R  R  HSS E+H  ++K  + + +P+LQ  YMY    ++T   A
Sbjct: 648 FSAVLRRWRHRHSSPEEHEAEFKRYEKRDVPSLQRAYMYAFAVQSTVHIA 697


>UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2;
           Deltaproteobacteria|Rep: Hydroxyacylglutathione
           hydrolase - Syntrophus aciditrophicus (strain SB)
          Length = 235

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 38/135 (28%), Positives = 54/135 (40%)
 Frame = +1

Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483
           DN  YLI    T  A  VD    + +L  +E++ + L              GNE L+K  
Sbjct: 14  DNLGYLIFGDRT--AMAVDGGAVEDILSFLEKRRLELRWVVNTHSHYDHTSGNEALLKYS 71

Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663
               +   D    A+  ++E   K       +Q   TP HT   IC+         D+++
Sbjct: 72  RARFI---DCAALAVLGRLELEGKI------IQVYATPGHTRDSICFHT-------DTIL 115

Query: 664 FTGDTLFLGGCGRFF 708
            TGDTLF G  G  F
Sbjct: 116 LTGDTLFNGTVGNCF 130


>UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein;
           n=1; Myxococcus xanthus DK 1622|Rep:
           Metallo-beta-lactamase family protein - Myxococcus
           xanthus (strain DK 1622)
          Length = 483

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 2/122 (1%)
 Frame = +1

Query: 343 EAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519
           EA +VDP     V L  +  Q + L              G   L +     +V G     
Sbjct: 23  EALVVDPRRDVDVYLDVLRRQELRLRYVLQTHRQEDFVEGTSALARLAGAQVVAGRHPIT 82

Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA-PEEGNDSVVFTGDTLFLGGC 696
           G    ++    +  +G L +  L TP HT   + + V   P       VFTGD L  G  
Sbjct: 83  GHADVRMGERERLHLGALTLVALHTPGHTPESMSWAVYLDPHHAQAWGVFTGDALLAGET 142

Query: 697 GR 702
           GR
Sbjct: 143 GR 144


>UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1;
           Pseudoalteromonas atlantica T6c|Rep: Beta-lactamase-like
           - Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 288

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
 Frame = +1

Query: 514 RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL-- 687
           R  A  K ++     + G+  + C+ TP HT+  + Y +       D  VF GDTLF+  
Sbjct: 116 RFDAFDKLLQDGESLQFGSATLVCMSTPGHTSDSLSYII-------DDNVFVGDTLFMPD 168

Query: 688 GGCGR 702
           GG  R
Sbjct: 169 GGTAR 173


>UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1;
           Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain
           protein - Shewanella sediminis HAW-EB3
          Length = 354

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 20/47 (42%), Positives = 24/47 (51%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +G L +  + TP HT   IC  +          VFTGDTL LGG GR
Sbjct: 101 VGKLRLTIMHTPGHTADSICIVMK-------DRVFTGDTLLLGGTGR 140


>UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1;
           Pseudoalteromonas tunicata D2|Rep: Beta-lactamase-like
           protein - Pseudoalteromonas tunicata D2
          Length = 283

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 20/48 (41%), Positives = 26/48 (54%)
 Frame = +1

Query: 556 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699
           F +G   V  L TP HT+  +CY V    +GN   VF GDT+F+   G
Sbjct: 128 FPLGQFTVTVLATPGHTSDSVCYVV----DGN---VFVGDTVFMPDSG 168


>UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1;
           Acinetobacter baumannii ATCC 17978|Rep: Putative
           uncharacterized protein - Acinetobacter baumannii
           (strain ATCC 17978 / NCDC KC 755)
          Length = 186

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 18/55 (32%), Positives = 27/55 (49%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           +E     K+G    +  F P HT GH+ ++       N  +++TGD LF G  GR
Sbjct: 84  LEGGEVLKLGEDEFEVRFAPGHTPGHVMFY-----NKNHGLLWTGDVLFKGSIGR 133


>UniRef50_A3L9H1 Cluster: Putative uncharacterized protein; n=1;
           Pseudomonas aeruginosa 2192|Rep: Putative
           uncharacterized protein - Pseudomonas aeruginosa 2192
          Length = 270

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 21/43 (48%), Positives = 22/43 (51%)
 Frame = +1

Query: 556 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684
           F IG L  Q L  P HT   I Y V      N+ VVF GDTLF
Sbjct: 129 FYIGPLRTQALAVPGHTPADIAYLV------NNEVVFVGDTLF 165


>UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2;
           Sulfolobus|Rep: Putative uncharacterized protein -
           Sulfolobus solfataricus
          Length = 209

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 19/55 (34%), Positives = 28/55 (50%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           V+   + ++G   ++ + TP HT G IC          +  +FTGDTLF G  GR
Sbjct: 110 VKEGDEIELGGEKLKIIETPGHTMGSICIIA-------NGYIFTGDTLFYGTVGR 157


>UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           uncharacterized protein - Uncultured methanogenic
           archaeon RC-I
          Length = 208

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +1

Query: 496 VYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGD 675
           ++G D     +   ++   +  +G++ ++ + TP HT G IC +     E     +FTGD
Sbjct: 90  MFGSDSPELKVDMVLKDGDEIDLGDVKLRVIHTPGHTPGSICLY-----EPVSKAMFTGD 144

Query: 676 TLF-LGGCGR 702
           T+F  GG GR
Sbjct: 145 TVFEEGGFGR 154


>UniRef50_A3CRI7 Cluster: Beta-lactamase domain protein; n=3;
           Methanomicrobiales|Rep: Beta-lactamase domain protein -
           Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498
           / JR1)
          Length = 200

 Score = 36.3 bits (80), Expect = 0.76
 Identities = 22/50 (44%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
 Frame = +1

Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGC-GRF 705
           +IGNL V  + TP HT G IC +  A     + ++F+GDT+F GG  GR+
Sbjct: 106 RIGNLCV--IHTPGHTPGGICLYNEA-----EKLLFSGDTVFTGGSFGRY 148


>UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase
           family; n=6; Proteobacteria|Rep: Zn-dependent
           hydrolases, glyoxylase family - Idiomarina loihiensis
          Length = 292

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 17/51 (33%), Positives = 28/51 (54%)
 Frame = +1

Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684
           K ++    F +G++ ++ + TP HT   I Y +      N++ VF GDTLF
Sbjct: 127 KLLQDGETFHLGSMTIRVIHTPGHTPADIAYVI------NENKVFVGDTLF 171


>UniRef50_Q0RV20 Cluster: Possible hydrolase; n=1; Rhodococcus sp.
           RHA1|Rep: Possible hydrolase - Rhodococcus sp. (strain
           RHA1)
          Length = 454

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
 Frame = +1

Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTGDTLFLGGCGR 702
           +G L ++ L TP HT  H+C+ +    +G+  V VFTG +L +G   R
Sbjct: 101 LGGLRLRALTTPGHTHEHLCFLLL---DGDTEVGVFTGGSLIVGSAAR 145


>UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1;
           Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
           Beta-lactamase domain protein - Caldicellulosiruptor
           saccharolyticus (strain ATCC 43494 / DSM 8903)
          Length = 199

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 19/48 (39%), Positives = 27/48 (56%)
 Frame = +1

Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           + G+LN + + TP HT G  C+       G D ++F+GDTLF    GR
Sbjct: 113 EFGDLNFKVIHTPGHTPGSSCFLY-----GGD-ILFSGDTLFKDSYGR 154


>UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Beta-lactamase
           domain protein - Thermosinus carboxydivorans Nor1
          Length = 332

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 16/46 (34%), Positives = 24/46 (52%)
 Frame = +1

Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGD 675
           V    +  IG+    C+ TP HT GH+C +     E N  ++F+GD
Sbjct: 149 VREGYRLVIGDYEFTCITTPGHTPGHVCLY-----EPNRKILFSGD 189


>UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 215

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 19/60 (31%), Positives = 29/60 (48%)
 Frame = +1

Query: 523 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702
           A  + +E       G + +  + TP HT GH+  +   PE  +   +F GDT+F G  GR
Sbjct: 112 AADRTLEEGDVLDFGPIRLSVIETPGHTPGHVSVYF--PEAKS---IFVGDTIFAGSIGR 166


>UniRef50_A4QPZ2 Cluster: Putative uncharacterized protein; n=4;
           Dikarya|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 531

 Score = 35.9 bits (79), Expect = 1.00
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
 Frame = +1

Query: 172 PSGLSQRITKLYFRALIR--NQREAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKE 345
           P  ++Q   ++Y  AL+R  N      + E    + +D++ILP L   Y +  VDK T  
Sbjct: 33  PQLVNQAHPEIYMEALVRYPNDESIDQADEKRLVRKLDMRILPLLGVCYFFYYVDKTTLS 92

Query: 346 AAIVDPVEPKTVLKAVE 396
            A +  ++    LK  E
Sbjct: 93  YAAIFGLKEGLGLKGEE 109


>UniRef50_UPI00015978D7 Cluster: NrsD; n=1; Bacillus
           amyloliquefaciens FZB42|Rep: NrsD - Bacillus
           amyloliquefaciens FZB42
          Length = 919

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 16/45 (35%), Positives = 27/45 (60%)
 Frame = +1

Query: 550 TKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684
           T   IG+++++ + +P HTTG +C          D+ +FTGDT+F
Sbjct: 828 TVLNIGDISLKIILSPGHTTGSVCVLY-------DNFLFTGDTIF 865


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 640,116,599
Number of Sequences: 1657284
Number of extensions: 12012145
Number of successful extensions: 29035
Number of sequences better than 10.0: 299
Number of HSP's better than 10.0 without gapping: 27852
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28759
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57851245060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -