BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= an--0170 (717 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;... 186 4e-46 UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;... 185 1e-45 UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G... 169 4e-41 UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat... 152 1e-35 UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu... 130 4e-29 UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase... 126 5e-28 UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ... 118 2e-25 UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat... 116 4e-25 UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh... 115 1e-24 UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re... 114 2e-24 UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos... 114 2e-24 UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy... 113 3e-24 UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;... 113 4e-24 UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat... 113 5e-24 UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill... 112 7e-24 UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,... 112 7e-24 UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl... 112 9e-24 UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 109 9e-23 UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 109 9e-23 UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22 UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola... 103 3e-21 UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl... 101 2e-20 UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ... 96 9e-19 UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat... 75 1e-18 UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve... 93 8e-18 UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat... 92 1e-17 UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 92 1e-17 UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep... 91 2e-17 UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17 UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein;... 89 1e-16 UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep: H... 87 4e-16 UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc... 87 4e-16 UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ... 86 7e-16 UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola... 85 2e-15 UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 83 5e-15 UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ... 83 5e-15 UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ... 83 7e-15 UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr... 82 1e-14 UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ... 82 2e-14 UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola... 82 2e-14 UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot... 81 3e-14 UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox... 79 1e-13 UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 79 1e-13 UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion... 78 2e-13 UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola... 77 4e-13 UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo... 77 6e-13 UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 75 2e-12 UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit... 75 2e-12 UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ... 75 2e-12 UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000... 74 3e-12 UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat... 74 4e-12 UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 72 1e-11 UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot... 72 2e-11 UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola... 72 2e-11 UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 71 3e-11 UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri... 71 4e-11 UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 71 4e-11 UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ... 70 5e-11 UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;... 70 5e-11 UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox... 70 5e-11 UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot... 70 5e-11 UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur... 70 5e-11 UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who... 70 7e-11 UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat... 69 2e-10 UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur... 68 3e-10 UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase, putat... 68 3e-10 UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 66 6e-10 UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrola... 66 6e-10 UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome sh... 65 1e-09 UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 65 2e-09 UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfami... 64 2e-09 UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 64 4e-09 UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrola... 64 4e-09 UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat... 63 6e-09 UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrola... 63 8e-09 UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; ... 63 8e-09 UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrola... 63 8e-09 UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ... 62 1e-08 UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur... 62 1e-08 UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo... 62 2e-08 UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 62 2e-08 UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrola... 62 2e-08 UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola... 61 2e-08 UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas... 61 3e-08 UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 61 3e-08 UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 60 4e-08 UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot... 60 4e-08 UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione ... 60 7e-08 UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat... 60 7e-08 UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organ... 60 7e-08 UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9; ... 59 9e-08 UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 59 9e-08 UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; ... 59 9e-08 UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3; ... 59 9e-08 UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprot... 59 9e-08 UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC,... 59 1e-07 UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaprot... 59 1e-07 UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 58 2e-07 UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily prot... 58 2e-07 UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ... 57 4e-07 UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ... 57 4e-07 UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily hydr... 57 4e-07 UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syn... 56 9e-07 UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met... 56 1e-06 UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily prot... 56 1e-06 UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; ... 56 1e-06 UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 56 1e-06 UniRef50_Q0RV06 Cluster: Possible hydrolase; n=11; Actinomycetal... 56 1e-06 UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola... 55 2e-06 UniRef50_A5INW0 Cluster: Beta-lactamase domain protein; n=30; St... 55 2e-06 UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrola... 55 2e-06 UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira... 54 4e-06 UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter... 54 4e-06 UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 54 4e-06 UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c... 54 4e-06 UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ... 54 5e-06 UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clo... 54 5e-06 UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily prot... 54 5e-06 UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamil... 53 8e-06 UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 53 8e-06 UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2; sul... 52 1e-05 UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1; Met... 52 1e-05 UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5; ... 52 1e-05 UniRef50_Q71KM2 Cluster: Glyoxalase II; n=8; Plasmodium|Rep: Gly... 52 2e-05 UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular o... 52 2e-05 UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; ... 51 2e-05 UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrola... 51 3e-05 UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05 UniRef50_A6BZ99 Cluster: Putative uncharacterized protein; n=2; ... 50 4e-05 UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 50 6e-05 UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily prot... 50 6e-05 UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot... 50 6e-05 UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ... 50 8e-05 UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 49 1e-04 UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosar... 49 1e-04 UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2... 48 2e-04 UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily prot... 48 2e-04 UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon... 48 2e-04 UniRef50_Q1AVJ8 Cluster: Beta-lactamase-like protein; n=4; Bacte... 48 3e-04 UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=1... 47 5e-04 UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4... 47 5e-04 UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus... 47 5e-04 UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acine... 46 7e-04 UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Hal... 46 7e-04 UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Ac... 46 0.001 UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, wh... 46 0.001 UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; ... 46 0.001 UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba... 45 0.002 UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily prot... 45 0.002 UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein; ... 45 0.002 UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-P... 45 0.002 UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syn... 45 0.002 UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bac... 44 0.003 UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; ... 44 0.003 UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti... 44 0.003 UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2; Chloroflexus|... 44 0.003 UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase relate... 44 0.003 UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate sulfurtransfer... 44 0.003 UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrola... 44 0.004 UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Can... 44 0.004 UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like d... 44 0.004 UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|R... 44 0.005 UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; ... 44 0.005 UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16; Proteobacter... 44 0.005 UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005 UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Vic... 44 0.005 UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007 UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20; P... 43 0.007 UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyo... 43 0.009 UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia gloss... 43 0.009 UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1; Rubro... 43 0.009 UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2; Ros... 43 0.009 UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1; ... 43 0.009 UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas s... 42 0.011 UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein; ... 42 0.011 UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1; Sol... 42 0.011 UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep... 42 0.011 UniRef50_Q81Q95 Cluster: Metallo-beta-lactamase/rhodanese-like d... 42 0.015 UniRef50_Q1AUZ4 Cluster: Beta-lactamase-like protein; n=1; Rubro... 42 0.015 UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cy... 42 0.015 UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; ... 42 0.015 UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione hydro... 42 0.020 UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alk... 42 0.020 UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1; Mar... 42 0.020 UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;... 42 0.020 UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 41 0.027 UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep: Hyd... 41 0.027 UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3; ... 41 0.027 UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bac... 41 0.027 UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; ... 41 0.035 UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor... 41 0.035 UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;... 41 0.035 UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; ... 40 0.046 UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium di... 40 0.046 UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n... 40 0.061 UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrola... 40 0.061 UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1... 40 0.061 UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11; Ga... 40 0.061 UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein; ... 40 0.061 UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120; Ba... 40 0.081 UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Re... 39 0.11 UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Re... 39 0.11 UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11 UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clo... 39 0.11 UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11 UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: Yqg... 39 0.11 UniRef50_Q4WA58 Cluster: Metallo-beta-lactamase domain protein; ... 39 0.11 UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2; Ana... 39 0.14 UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 39 0.14 UniRef50_A4S568 Cluster: Predicted protein; n=1; Ostreococcus lu... 39 0.14 UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37; Actinomyceta... 38 0.19 UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 38 0.19 UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium p... 38 0.19 UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.19 UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bac... 38 0.19 UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium c... 38 0.19 UniRef50_Q7QZA0 Cluster: GLP_567_43928_43275; n=1; Giardia lambl... 38 0.19 UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon... 38 0.25 UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily prot... 38 0.25 UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clost... 38 0.25 UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 38 0.33 UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; ... 38 0.33 UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bac... 38 0.33 UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1... 38 0.33 UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 38 0.33 UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region f... 37 0.43 UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; ... 37 0.43 UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 37 0.43 UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; ... 37 0.57 UniRef50_Q1VZM6 Cluster: Metallo-beta-lactamase superfamily prot... 37 0.57 UniRef50_A1D100 Cluster: FAD binding domain protein; n=4; Tricho... 37 0.57 UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 36 0.76 UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein; ... 36 0.76 UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalterom... 36 0.76 UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; She... 36 0.76 UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1; Pseud... 36 0.76 UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.76 UniRef50_A3L9H1 Cluster: Putative uncharacterized protein; n=1; ... 36 0.76 UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; ... 36 0.76 UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.76 UniRef50_A3CRI7 Cluster: Beta-lactamase domain protein; n=3; Met... 36 0.76 UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase fam... 36 1.00 UniRef50_Q0RV20 Cluster: Possible hydrolase; n=1; Rhodococcus sp... 36 1.00 UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1; Cal... 36 1.00 UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1; The... 36 1.00 UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syn... 36 1.00 UniRef50_A4QPZ2 Cluster: Putative uncharacterized protein; n=4; ... 36 1.00 UniRef50_UPI00015978D7 Cluster: NrsD; n=1; Bacillus amyloliquefa... 36 1.3 UniRef50_UPI000023EAC6 Cluster: hypothetical protein FG07959.1; ... 36 1.3 UniRef50_A1ZPC4 Cluster: Metallo-beta-lactamase family protein; ... 36 1.3 UniRef50_Q188Q8 Cluster: Putative hydrolase; n=2; Clostridium di... 35 1.7 UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo... 35 1.7 UniRef50_Q24F45 Cluster: Hydroxyacylglutathione hydrolase, putat... 35 1.7 UniRef50_Q4W945 Cluster: Metallo-beta-lactamase domain protein; ... 35 1.7 UniRef50_Q8TUW9 Cluster: Zn-dependent hydrolase; n=1; Methanopyr... 35 1.7 UniRef50_A4YDP4 Cluster: Beta-lactamase domain protein; n=1; Met... 35 1.7 UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3 UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5; B... 35 2.3 UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione hydro... 35 2.3 UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4; Deino... 35 2.3 UniRef50_A5URH7 Cluster: Beta-lactamase domain protein; n=4; Chl... 35 2.3 UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein; ... 35 2.3 UniRef50_A0LDZ9 Cluster: Beta-lactamase domain protein; n=1; Mag... 35 2.3 UniRef50_A0B5Y5 Cluster: Beta-lactamase domain protein; n=1; Met... 35 2.3 UniRef50_Q8NU87 Cluster: Zn-dependent hydrolases, including glyo... 34 3.0 UniRef50_A1SFV7 Cluster: Beta-lactamase domain protein; n=1; Noc... 34 3.0 UniRef50_Q5KE04 Cluster: Putative uncharacterized protein; n=2; ... 34 3.0 UniRef50_Q2CF40 Cluster: Hydrolase 11; n=1; Oceanicola granulosu... 34 4.0 UniRef50_Q1IQE8 Cluster: Beta-lactamase-like; n=2; Acidobacteria... 34 4.0 UniRef50_A7ISC4 Cluster: HagH; n=5; Neisseria|Rep: HagH - Neisse... 34 4.0 UniRef50_A5WCY4 Cluster: Beta-lactamase domain protein; n=5; Pro... 34 4.0 UniRef50_UPI000050F771 Cluster: COG0491: Zn-dependent hydrolases... 33 5.3 UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein; ... 33 5.3 UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121; Proteobacte... 33 5.3 UniRef50_Q4WQZ6 Cluster: Metallo-beta-lactamase domain protein, ... 33 5.3 UniRef50_Q4WA79 Cluster: Metallo-beta-lactamase domain protein, ... 33 5.3 UniRef50_O30264 Cluster: Putative uncharacterized protein; n=1; ... 33 5.3 UniRef50_O28526 Cluster: Putative uncharacterized protein; n=1; ... 33 5.3 UniRef50_Q9ACM3 Cluster: Cytosine-specific methyltransferase; n=... 33 7.0 UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Ros... 33 7.0 UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3; Deh... 33 7.0 UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-l... 33 7.0 UniRef50_Q2U887 Cluster: Glyoxylase; n=2; Trichocomaceae|Rep: Gl... 33 7.0 UniRef50_A7D422 Cluster: Beta-lactamase domain protein; n=2; Hal... 33 7.0 UniRef50_A5YSG8 Cluster: Thiosulfate sulfurtransferase/hydrolase... 33 7.0 UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1; A... 33 7.0 UniRef50_UPI0000499269 Cluster: metallo-beta-lactamase superfami... 33 9.3 UniRef50_Q73QI1 Cluster: Metallo-beta-lactamase family protein; ... 33 9.3 UniRef50_Q1ARM7 Cluster: Beta-lactamase-like protein; n=1; Rubro... 33 9.3 UniRef50_Q0AZS8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3 UniRef50_A1ZW49 Cluster: Putative uncharacterized protein; n=1; ... 33 9.3 UniRef50_A0LWF9 Cluster: Beta-lactamase domain protein; n=1; Aci... 33 9.3 UniRef50_Q8MR51 Cluster: GH20064p; n=5; Diptera|Rep: GH20064p - ... 33 9.3 UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lambl... 33 9.3 UniRef50_A2DZQ6 Cluster: Metallo-beta-lactamase superfamily prot... 33 9.3 UniRef50_Q2UI96 Cluster: Zn-dependent hydrolases; n=4; Pezizomyc... 33 9.3 >UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35; Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus musculus (Mouse) Length = 260 Score = 186 bits (454), Expect = 4e-46 Identities = 84/145 (57%), Positives = 107/145 (73%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M V++LPAL DNYMYLI+D+ T+EAAIVDPV+P+ V++A ++ V L A Sbjct: 1 MKVELLPALTDNYMYLIIDEDTQEAAIVDPVQPQKVIEAAKKHHVKLTTVLTTHHHWDHA 60 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 GGNE L+K PGL VYGGDDRIGALT KV H + ++G+L+V+CL TPCHT+GHICYFV+ Sbjct: 61 GGNEKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVS 120 Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708 P S VFTGDTLF+ GCG+F+ Sbjct: 121 KPGSSEPSAVFTGDTLFVAGCGKFY 145 >UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15; Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo sapiens (Human) Length = 260 Score = 185 bits (450), Expect = 1e-45 Identities = 83/145 (57%), Positives = 103/145 (71%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M V++LPAL DNYMYL++D TKEAAIVDPV+P+ V+ A + GV L A Sbjct: 1 MKVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHA 60 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 GGNE L+K GL VYGGDDRIGALT K+ H + ++G+LNV+CL TPCHT+GHICYFV+ Sbjct: 61 GGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVS 120 Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708 P VFTGDTLF+ GCG+F+ Sbjct: 121 KPGGSEPPAVFTGDTLFVAGCGKFY 145 >UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito) Length = 302 Score = 169 bits (412), Expect = 4e-41 Identities = 91/194 (46%), Positives = 114/194 (58%), Gaps = 7/194 (3%) Frame = +1 Query: 148 LARFVNSLPSGLSQRITKLYFRALIRNQREAHSSQEDHQYKNMDVKILPALQDNYMYLIV 327 ++ +N LP LSQ +T YF + R ++ + M VK +PAL+DN+MYL+V Sbjct: 1 MSALLNRLPHRLSQGLTAAYFTVNSWSIRRRSTAVQTTDMTRMTVKKIPALKDNFMYLVV 60 Query: 328 DKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG------ 489 TK AAIVDPVEP VL+ +E GV+L AGGN DL K Sbjct: 61 CNETKNAAIVDPVEPDRVLQVAKESGVSLNKVLTTHHHWDHAGGNADLFKRYQADTSLGP 120 Query: 490 LIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVF 666 L +YGG D+RI LT V + +IGNL V+C+ TPCHTT HICY++ PE D VVF Sbjct: 121 LQIYGGNDERIDNLTNPVGQDDTLEIGNLKVRCISTPCHTTSHICYYIETPE---DKVVF 177 Query: 667 TGDTLFLGGCGRFF 708 TGDTLFL GCGRFF Sbjct: 178 TGDTLFLAGCGRFF 191 >UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putative, expressed; n=3; Oryza sativa|Rep: Hydroxyacylglutathione hydrolase, putative, expressed - Oryza sativa subsp. japonica (Rice) Length = 258 Score = 152 bits (368), Expect = 1e-35 Identities = 76/147 (51%), Positives = 96/147 (65%), Gaps = 4/147 (2%) Frame = +1 Query: 280 VKILPA--LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +KI+P L+DNY YLIVD++TK AA VDPVEP+ VL A E GV + A Sbjct: 1 MKIIPVACLEDNYAYLIVDESTKSAAAVDPVEPEKVLAAAAEVGVRIDCVLTTHHHWDHA 60 Query: 454 GGNEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHICYF 627 GGNE + + PG+ VYGG D + T +VE+ TK +G ++ + CL TPCHT GHI Y+ Sbjct: 61 GGNEKMAQSVPGIKVYGGSLDNVKGCTDQVENGTKLSLGKDIEILCLHTPCHTKGHISYY 120 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 VT+ EE D VFTGDTLF+ GCGRFF Sbjct: 121 VTSKEE-EDPAVFTGDTLFIAGCGRFF 146 >UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo sapiens (Human) Length = 291 Score = 130 bits (313), Expect = 4e-29 Identities = 58/142 (40%), Positives = 89/142 (62%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M VK++P L+DNYMYL++++ T+EA VD PK +L+ V +GV+L A Sbjct: 1 MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 GN +L + RPGL V G D+RI +LT+++ H + + G ++V+CL TP HT GH+ YF+ Sbjct: 61 RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLW 120 Query: 634 APEEGNDSVVFTGDTLFLGGCG 699 + + +F+GD L + GCG Sbjct: 121 EDDCPDPPALFSGDALSVAGCG 142 >UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase II, partial; n=1; Pan troglodytes|Rep: PREDICTED: similar to glyoxalase II, partial - Pan troglodytes Length = 284 Score = 126 bits (304), Expect = 5e-28 Identities = 53/86 (61%), Positives = 67/86 (77%) Frame = +1 Query: 451 AGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 AGGNE L++ + GL VYGGDDRIGALT K+ H + ++G+LNV+CL TPCHT+GHICYFV Sbjct: 3 AGGNEKLVELQSGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFV 62 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 + P VFTGDTLF+ GCG+F+ Sbjct: 63 SKPGGSEPPAVFTGDTLFVAGCGKFY 88 >UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 260 Score = 118 bits (283), Expect = 2e-25 Identities = 56/146 (38%), Positives = 84/146 (57%), Gaps = 3/146 (2%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAI-VDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 VK L DN+MY++ + AA+ VD V + + +++ +++ G Sbjct: 4 VKSLLRRADNFMYIVKKSSEARAALLVDLVNEEDYKELADKENIDITAVLTTHHHYDHCG 63 Query: 457 GNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636 GNE ++ P +++ GGD RI A+ + V+H + L ++CL TPCHT+GHICY +T Sbjct: 64 GNEGFRRQFPNVMILGGDSRIPAMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITN 123 Query: 637 PEEGNDS--VVFTGDTLFLGGCGRFF 708 P + S VVFTGDTLF+ GCGRFF Sbjct: 124 PAADSTSPGVVFTGDTLFIAGCGRFF 149 >UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione hydrolase, putative - Babesia bovis Length = 319 Score = 116 bits (280), Expect = 4e-25 Identities = 53/146 (36%), Positives = 85/146 (58%), Gaps = 2/146 (1%) Frame = +1 Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 +V +P QDNY Y++VD K A VDP EP+ +L ++E+ + L +G Sbjct: 68 EVITVPLFQDNYGYIVVDPDGKHAFCVDPAEPRKILSVIDERKLTLKAVFCTHKHHDHSG 127 Query: 457 GNEDLIKERPGLIVYGGDDR-IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 GN ++ + PG+ VYG ++ + +T + ++G L ++ + PCHT GH+ Y+VT Sbjct: 128 GNLEMARIIPGIPVYGSNNEDMAGMTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVT 187 Query: 634 APEEGN-DSVVFTGDTLFLGGCGRFF 708 P + ++FTGDT+F+GGCGRFF Sbjct: 188 NPSDPTMQPLMFTGDTIFIGGCGRFF 213 >UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 2 SCAF14661, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 400 Score = 115 bits (276), Expect = 1e-24 Identities = 59/175 (33%), Positives = 90/175 (51%), Gaps = 5/175 (2%) Frame = +1 Query: 190 RITKLYFRALIRNQRE----AHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIV 357 R+ +Y++ ++ RE HS+ + + + + L DNY YL++D A A +V Sbjct: 23 RLGYMYYKRQMKKARELYPAGHSTAQPCDLNGIKIIPISVLSDNYSYLVIDTAAGVAVVV 82 Query: 358 DPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTK 534 DP +P+TV ++E+GV L +GGN++L K VYG D I LT Sbjct: 83 DPADPQTVQAVIKEEGVVLEAILCTHKHWDHSGGNKELKKLHTSCRVYGSATDNIPGLTH 142 Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 + H G L+ + LFTP HT GH+ Y + G+ S +F+GD +FL GCG Sbjct: 143 PLSHRDSIAFGRLHFEALFTPGHTVGHMIYLLDGRTVGSPSSLFSGDLVFLSGCG 197 >UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep: Isoform 3 of Q8N490 - Homo sapiens (Human) Length = 361 Score = 114 bits (275), Expect = 2e-24 Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 5/174 (2%) Frame = +1 Query: 202 LYFRALIRNQR----EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVE 369 L++R +R R + HS + + + V +P L DNY YLI+D + A VDP + Sbjct: 67 LFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSD 126 Query: 370 PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTKKVEH 546 P+ V ++E++GV L +GGN DL + VYG D I LT + H Sbjct: 127 PRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCH 186 Query: 547 NTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 +G L ++ L TP HT GH+ Y + S +F+GD LFL GCGR F Sbjct: 187 QDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF 240 >UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens (Human) Length = 385 Score = 114 bits (275), Expect = 2e-24 Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 5/174 (2%) Frame = +1 Query: 202 LYFRALIRNQR----EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVE 369 L++R +R R + HS + + + V +P L DNY YLI+D + A VDP + Sbjct: 91 LFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSD 150 Query: 370 PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTKKVEH 546 P+ V ++E++GV L +GGN DL + VYG D I LT + H Sbjct: 151 PRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCH 210 Query: 547 NTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 +G L ++ L TP HT GH+ Y + S +F+GD LFL GCGR F Sbjct: 211 QDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTF 264 >UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomycota|Rep: Function: RSP29 precursor - Aspergillus niger Length = 299 Score = 113 bits (273), Expect = 3e-24 Identities = 60/140 (42%), Positives = 82/140 (58%), Gaps = 5/140 (3%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 471 +NY YL+ D+ TKE+ I+DP P V ++ Q + L AGGN ++ Sbjct: 58 NNYAYLVTDEPTKESVIIDPANPPEVAPTLKSQIDAGKIKLTSIVNTHHHWDHAGGNNEI 117 Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEG 648 +K L V GG + ++TK H FKIG ++V+ L TPCHT ICYF+ ++G Sbjct: 118 LKTFGQLSVIGGKN-CQSVTKTPAHGEVFKIGERISVKALHTPCHTQDSICYFM---QDG 173 Query: 649 NDSVVFTGDTLFLGGCGRFF 708 +D VVFTGDTLF+GGCGRFF Sbjct: 174 DDKVVFTGDTLFIGGCGRFF 193 >UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10; Ascomycota|Rep: Hydroxyacylglutathione hydrolase - Schizosaccharomyces pombe (Fission yeast) Length = 256 Score = 113 bits (272), Expect = 4e-24 Identities = 59/139 (42%), Positives = 81/139 (58%), Gaps = 4/139 (2%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG----VNLXXXXXXXXXXXXAGGNEDL 471 +NY YL+ TK AIVDP EP++V+ ++E+ ++L AGGNED+ Sbjct: 16 NNYAYLLTCDKTKITAIVDPAEPESVIPVIKEKTAKKEIDLQYILTTHHHYDHAGGNEDI 75 Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651 + P L VYGG + G +T + FK+G + V+ L TPCHT ICY+V++P + Sbjct: 76 LSYFPSLKVYGGKNASG-VTYTPKDKEIFKVGEVQVEALHTPCHTQDSICYYVSSPSK-- 132 Query: 652 DSVVFTGDTLFLGGCGRFF 708 VFTGDTLF GCGRFF Sbjct: 133 -RAVFTGDTLFTSGCGRFF 150 >UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putative; n=1; Filobasidiella neoformans|Rep: Hydroxyacylglutathione hydrolase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 274 Score = 113 bits (271), Expect = 5e-24 Identities = 60/146 (41%), Positives = 82/146 (56%), Gaps = 3/146 (2%) Frame = +1 Query: 280 VKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +K+LP A DN+MYLI+D ++ EAA+VDP + + AV+EQ N+ + Sbjct: 25 MKVLPYKARSDNWMYLIID-SSNEAAVVDPYDANKISGAVKEQRANVTSLITTHHHADHS 83 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHICYFV 630 GGN + P L VY G + V+ F +G ++ V+CL TPCHT IC+F+ Sbjct: 84 GGNSKFLSLHPNLKVYAGSTQSPGTNTVVKDGDTFTLGQDITVKCLHTPCHTQDSICFFL 143 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 + G VFTGDTLFL GCGRFF Sbjct: 144 EDKKTGQRG-VFTGDTLFLAGCGRFF 168 >UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrillogenesis regulator 1; n=1; Monodelphis domestica|Rep: PREDICTED: similar to myofibrillogenesis regulator 1 - Monodelphis domestica Length = 286 Score = 112 bits (270), Expect = 7e-24 Identities = 58/156 (37%), Positives = 80/156 (51%), Gaps = 1/156 (0%) Frame = +1 Query: 235 EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414 + HS+ + + + V +P L DNY YLI+D +K A VDP +P+ V A+E++GV L Sbjct: 36 DGHSAVQPRVFNGVKVLPIPVLLDNYSYLIIDTQSKLAVAVDPSDPRAVQAAIEKEGVTL 95 Query: 415 XXXXXXXXXXXXAGGNEDLIKERPGLIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLF 591 +GGN +L + G VYG D I LT + H +G L Q L Sbjct: 96 VAILCTHKHWDHSGGNRELRRHHRGCRVYGNPQDGIAHLTHPLCHQDMVSVGRLQFQALA 155 Query: 592 TPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 TP HT GH+ Y + S +F+GD LFL GCG Sbjct: 156 TPGHTRGHMVYVLDGEPYKGPSCLFSGDLLFLSGCG 191 >UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein, partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 268 Score = 112 bits (270), Expect = 7e-24 Identities = 54/141 (38%), Positives = 80/141 (56%), Gaps = 1/141 (0%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +P L+DNY YL+++KA+ AA++DP + + V + +E+Q V L +GGN+ Sbjct: 6 IPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQLTAILTTHKHWDHSGGNQK 65 Query: 469 LIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 L L VYGG+ D + K++ F+IG L LFTP HT GH+ Y + ++ Sbjct: 66 LKSLHSNLAVYGGERDGVPGCNHKLKDGDSFQIGGLKFTALFTPGHTVGHMVYLLDRSDK 125 Query: 646 GNDSVVFTGDTLFLGGCGRFF 708 + +FTGD LFLGG GR F Sbjct: 126 NLPNSLFTGDILFLGGNGRMF 146 >UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Glyoxalase IIB - Plasmodium falciparum Length = 263 Score = 112 bits (269), Expect = 9e-24 Identities = 56/150 (37%), Positives = 83/150 (55%), Gaps = 7/150 (4%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459 V ++P L DN+ Y+I+D+ TK+AA +DPVEP VLK +E V L +GG Sbjct: 7 VLVVPVLNDNFSYVIIDEKTKKAASIDPVEPDKVLKRIETANVELEYVLCTHHHYDHSGG 66 Query: 460 NEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636 N + + + + V G + + +KV ++G LN++ + PCHT GHI Y+V Sbjct: 67 NIRMRELKQNIKVVGSAYEPTPGVNEKVYDGQIIRLGELNIKAIHAPCHTKGHILYYVYK 126 Query: 637 PEEGNDS------VVFTGDTLFLGGCGRFF 708 +E ++FTGDTLF+ GCGRFF Sbjct: 127 TDEAKQEDHKYKPILFTGDTLFIAGCGRFF 156 >UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione hydrolase - Dictyostelium discoideum AX4 Length = 268 Score = 109 bits (261), Expect = 9e-23 Identities = 55/148 (37%), Positives = 81/148 (54%), Gaps = 5/148 (3%) Frame = +1 Query: 280 VKILPAL--QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEE--QGVNLXXXXXXXXXXX 447 +K+ P L +DNY YL++D+ K A +DP EP V+ ++ + + Sbjct: 1 MKVQPVLVNKDNYSYLVIDEKNKVAIAIDPCEPNKVISSLSSISSDIKINSVFTTHHHWD 60 Query: 448 XAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 AGGN + + VYG D+R +TKK+E+N KIG+L ++ L P HT+ H+ Y Sbjct: 61 HAGGNNLIKTIIKDINVYGRDERFEGITKKLENNEVLKIGSLKIKTLDAPAHTSSHVLYL 120 Query: 628 VTAPEEGND-SVVFTGDTLFLGGCGRFF 708 + E N +FTGDTLF+GGCGR F Sbjct: 121 IEDENEPNQVKSLFTGDTLFIGGCGRLF 148 >UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione hydrolase - Schizosaccharomyces pombe (Fission yeast) Length = 256 Score = 109 bits (261), Expect = 9e-23 Identities = 55/140 (39%), Positives = 82/140 (58%), Gaps = 4/140 (2%) Frame = +1 Query: 301 QDNYMYLIVDKATKEAAIVDPVEPKTVL----KAVEEQGVNLXXXXXXXXXXXXAGGNED 468 QDNY YL++ + T++AAIVDP E V+ K ++ + ++L +GGN + Sbjct: 15 QDNYAYLLLCEETRQAAIVDPAEVNVVMPILKKKLKNKEIDLQAILTTHHHADHSGGNLN 74 Query: 469 LIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 L KE P + +YGG D+ G ++ ++ +IGN+ ++ L TPCHT IC++ Sbjct: 75 LKKEFPHVTIYGGSDQNG-VSHVLQDKETLRIGNVQIEALHTPCHTRDSICFYA---HSS 130 Query: 649 NDSVVFTGDTLFLGGCGRFF 708 N+ VFTGDTLF GCGRFF Sbjct: 131 NEHAVFTGDTLFNAGCGRFF 150 >UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 268 Score = 107 bits (258), Expect = 2e-22 Identities = 58/153 (37%), Positives = 79/153 (51%), Gaps = 5/153 (3%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGV---NLXXXXXXXXXX 444 M + + +DNY Y++ A VD + + V A E+ G+ N+ Sbjct: 1 MKIHPVAVREDNYAYILQSSVDGRAVFVDVFDVEAVSGAAEKLGIPNENVVGLLTTHHHF 60 Query: 445 XXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFK--IGNLNVQCLFTPCHTTGHI 618 +GGNE PG +YGG D+I ALTK V + +G ++++C+ TPCHT HI Sbjct: 61 DHSGGNEAFAHAYPGRPIYGGSDKIPALTKLVHDADRISELLGGVSIECVATPCHTQDHI 120 Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF*RH 717 CY VT S VFTGDTLF+ GCGRFF H Sbjct: 121 CYHVTDTTTA-QSGVFTGDTLFISGCGRFFEGH 152 >UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase; n=13; Bacteria|Rep: Probable hydroxyacylglutathione hydrolase - Synechocystis sp. (strain PCC 6803) Length = 257 Score = 103 bits (248), Expect = 3e-21 Identities = 57/149 (38%), Positives = 75/149 (50%), Gaps = 4/149 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 MD+ LPAL DNY++L+ D+ +AA+VDP E K VL +E G +L Sbjct: 1 MDIHRLPALADNYIFLLHDRQRNQAAVVDPAEAKPVLDCLETLGADLVTIYNTHHHGDHV 60 Query: 454 GGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624 G N +L+ + P L VYGG RI T + + + F P HT GHI Y Sbjct: 61 GANRELLAKYPNLEVYGGVEDQGRIPGQTVFLRDGDRLSFADREATVYFVPGHTRGHIAY 120 Query: 625 FVTAPEEGND-SVVFTGDTLFLGGCGRFF 708 + AP G +F GDT+F GGCGR F Sbjct: 121 YF-APGSGETIGDLFCGDTIFAGGCGRLF 148 >UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep: Hydroxyacylglutathione hydrolase cytoplasmic - Candidatus Pelagibacter ubique HTCC1002 Length = 239 Score = 101 bits (241), Expect = 2e-20 Identities = 59/148 (39%), Positives = 82/148 (55%), Gaps = 3/148 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M+++I+ LQDNY YLIVDKA A ++DP E K V+K +E++ ++L Sbjct: 1 MEIQIIRCLQDNYSYLIVDKAKNIACVIDPSEAKPVIKYLEDKNIHLKYILNTHHHYDHV 60 Query: 454 GGNEDLIKERPG--LIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624 GGN++L KE+ G +I Y GD DRI + V + N + P HT GHIC+ Sbjct: 61 GGNKEL-KEKYGASVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICF 119 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + N+ VFTGDTLF GCG+ F Sbjct: 120 YFY-----NEESVFTGDTLFSLGCGKIF 142 >UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 659 Score = 95.9 bits (228), Expect = 9e-19 Identities = 54/135 (40%), Positives = 76/135 (56%), Gaps = 5/135 (3%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQ----GVNLXXXXXXXXXXXXAGGNEDL 471 +NY YL+ D+ TK++ I+DP P V+ +E Q +NL AGGN ++ Sbjct: 394 NNYAYLVTDEPTKQSVIIDPANPPEVVPELEAQTKAGKINLTAIVNTHHHWDHAGGNNEV 453 Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEG 648 +K + V GG D ++TK H FKIG+ ++V L TPCHT ICYF+ ++G Sbjct: 454 LKTFK-VPVIGGKD-CQSVTKTPAHGEVFKIGDRISVTALHTPCHTQDSICYFM---QDG 508 Query: 649 NDSVVFTGDTLFLGG 693 VFTGDTLF+GG Sbjct: 509 EQKAVFTGDTLFIGG 523 >UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putative; n=2; Theileria|Rep: Hydroxyacylglutathione hydrolase, putative - Theileria annulata Length = 362 Score = 74.5 bits (175), Expect(2) = 1e-18 Identities = 36/87 (41%), Positives = 49/87 (56%), Gaps = 2/87 (2%) Frame = +1 Query: 454 GGNEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GGN + K P + V G + +T V+H GNL ++CL CHT GHI Y+V Sbjct: 170 GGNNGIKKLVPDVEVVGSSYEETPGVTLPVKHEQTLTFGNLVIKCLKASCHTLGHIMYYV 229 Query: 631 TAPEEGNDS-VVFTGDTLFLGGCGRFF 708 P + ++F+GDTLF+ GCGRFF Sbjct: 230 YHPSNDHQQPLLFSGDTLFISGCGRFF 256 Score = 41.5 bits (93), Expect(2) = 1e-18 Identities = 19/46 (41%), Positives = 27/46 (58%) Frame = +1 Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414 +V I+P LQDNY Y++ D + A VDPVE + V +E + L Sbjct: 85 EVLIVPVLQDNYSYVLKDPESSNALCVDPVEYEKVYNVCKENDLEL 130 >UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 92.7 bits (220), Expect = 8e-18 Identities = 55/164 (33%), Positives = 79/164 (48%), Gaps = 6/164 (3%) Frame = +1 Query: 235 EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414 E HS ++ + + +P L DNY Y+IVD T A +VDP +P+ V + ++ + L Sbjct: 38 EPHSIALPWIHEGLKIIPVPFLYDNYSYIIVDITTSSAVVVDPSDPEAVKDVLNKEKLQL 97 Query: 415 XXXXXXXXXXXXAGGNEDLIKERPGLIVYGG--DDRIGAL-TKKV---EHNTKFKIGNLN 576 +GGN L + P + VYG DD G T+K N K+ L+ Sbjct: 98 EAVLTTHKHWDHSGGNTSLKADFPSVAVYGSELDDAPGLTHTRKPLCDISNFSGKVSQLS 157 Query: 577 VQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 TP HT GH+ Y + + +F+GD LFLGGCGR F Sbjct: 158 FTAFSTPGHTAGHVVYLLHGAVFNSVDSLFSGDLLFLGGCGRIF 201 >UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putative; n=8; Trypanosomatidae|Rep: Hydroxyacylglutathione hydrolase, putative - Leishmania major Length = 295 Score = 92.3 bits (219), Expect = 1e-17 Identities = 59/161 (36%), Positives = 82/161 (50%), Gaps = 18/161 (11%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDP-VEPKTVLKAVEE----QG-----VNLXXXXX 429 V ++P L+DN+ YLI D T A VD + K +L +EE QG Sbjct: 15 VTVVPTLKDNFSYLINDHTTHTLAAVDVNADYKPILTYIEEHLKQQGNADVTYTFSTILS 74 Query: 430 XXXXXXXAGGNEDLIKER-------PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCL 588 +GGN L E P ++V G +D I A+TK V + ++GNL+V+ + Sbjct: 75 THKHWDHSGGNAKLKAELEAMNSMVPVMVVGGANDGIPAVTKPVREGDRVQVGNLSVEVI 134 Query: 589 FTPCHTTGHICYFVTAPEEGNDSV-VFTGDTLFLGGCGRFF 708 PCHT GH+ Y V P+ ND V +FTGDT+F+ G G FF Sbjct: 135 DAPCHTRGHVLYKVQHPQHPNDGVALFTGDTMFIAGIGAFF 175 >UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 282 Score = 91.9 bits (218), Expect = 1e-17 Identities = 54/154 (35%), Positives = 79/154 (51%), Gaps = 6/154 (3%) Frame = +1 Query: 265 YKNMDVKILP---ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG--VNLXXXXX 429 Y+ M + +P DNY YL+VD +K A ++DP P V + ++E+ L Sbjct: 25 YRKMHILPIPMRWGQGDNYAYLLVDDRSKNAWLIDPAVPLEVNEFIKEKKPKYELKAIVN 84 Query: 430 XXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHT 606 + GN++ ++ P L + G D +T H +G+ L+V L TPCHT Sbjct: 85 THHHYDHSDGNKEFHRKYPDLPIIAGKDS-PLVTYTPSHEEVIDLGDDLSVTALHTPCHT 143 Query: 607 TGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 ICY+V + G + VFTGDTLF+ GCGRFF Sbjct: 144 QDSICYYVKDAKTG-EKAVFTGDTLFISGCGRFF 176 >UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep: All0580 protein - Anabaena sp. (strain PCC 7120) Length = 257 Score = 91.5 bits (217), Expect = 2e-17 Identities = 51/148 (34%), Positives = 72/148 (48%), Gaps = 3/148 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M V L AL DNY++L+ D AA+VDP E + VLK + + L Sbjct: 1 MQVIRLAALSDNYIFLLHDSHKNIAAVVDPAEAEPVLKQLAQLKAELVAIFNTHHHNDHV 60 Query: 454 GGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624 GGN+ LI++ P + VYGG RI ++ + + + + +F P HT HI Y Sbjct: 61 GGNQKLIQKFPQVKVYGGAKDQGRIPGQQVFLQPGDRVQFADRVAEVIFVPGHTRAHIAY 120 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + + +F GDTLF GGCGR F Sbjct: 121 YFPPQTDDTPGELFCGDTLFAGGCGRLF 148 >UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 722 Score = 89.8 bits (213), Expect = 6e-17 Identities = 56/136 (41%), Positives = 71/136 (52%), Gaps = 1/136 (0%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 DNY YL+VD +KEA ++DP P AGGNE+L+ E Sbjct: 491 DNYAYLVVDDKSKEAVVIDPAHPAD--------------------HWDHAGGNEELLSEL 530 Query: 484 -PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 L + GG D +TK H F IG++ V+ L TPCHT IC+F+ ++GND V Sbjct: 531 GQPLEIIGGKD-CKKVTKTPPHGATFNIGDIAVKALHTPCHTQDSICFFM---QDGNDKV 586 Query: 661 VFTGDTLFLGGCGRFF 708 VFTGDTLF GG FF Sbjct: 587 VFTGDTLFHGGEFLFF 602 >UniRef50_UPI0000E4A277 Cluster: PREDICTED: hypothetical protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 280 Score = 88.6 bits (210), Expect = 1e-16 Identities = 43/129 (33%), Positives = 70/129 (54%), Gaps = 1/129 (0%) Frame = +1 Query: 235 EAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414 + HS E + + + + +P L+DNY YL+++KA+ AA++DP + + V + +E+Q V L Sbjct: 29 DGHSVVEHTEVEGVIILPIPYLKDNYAYLVIEKASNIAAVIDPGDAEAVQRVIEQQNVQL 88 Query: 415 XXXXXXXXXXXXAGGNEDLIKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLF 591 +GGN+ L L VYGG+ D + +K++ F+IG L LF Sbjct: 89 TAILTTHKHWDHSGGNQTLKSLHSNLAVYGGERDGVPGCNRKLKDGDSFQIGGLKFTALF 148 Query: 592 TPCHTTGHI 618 TP HT G + Sbjct: 149 TPGHTVGRM 157 >UniRef50_Q96BZ3 Cluster: HAGHL protein; n=2; Homo sapiens|Rep: HAGHL protein - Homo sapiens (Human) Length = 203 Score = 87.0 bits (206), Expect = 4e-16 Identities = 39/97 (40%), Positives = 61/97 (62%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M VK++P L+DNYMYL++++ T+EA VD PK +L+ V +GV+L A Sbjct: 1 MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHA 60 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKI 564 GN +L + RPGL V G D+RI +LT+++ H + ++ Sbjct: 61 RGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRV 97 >UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitochondrial precursor; n=10; Saccharomycetales|Rep: Hydroxyacylglutathione hydrolase, mitochondrial precursor - Saccharomyces cerevisiae (Baker's yeast) Length = 285 Score = 87.0 bits (206), Expect = 4e-16 Identities = 48/141 (34%), Positives = 74/141 (52%), Gaps = 7/141 (4%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVL-KAVEEQGVNLXXXXXXXXXXXXAGGN----EDL 471 NY YL+ + + + ++DP EP V K E+ ++ +GGN L Sbjct: 26 NYSYLLSTEDRRNSWLIDPAEPLEVSPKLSAEEKKSIDAIVNTHHHYDHSGGNLALYSIL 85 Query: 472 IKERPG--LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 +E G + + GG +T+ ++ ++ +GNL V C+ TPCHT ICY++ E Sbjct: 86 CQENSGHDIKIIGGSKSSPGVTEVPDNLQQYHLGNLRVTCIRTPCHTKDSICYYIKDLET 145 Query: 646 GNDSVVFTGDTLFLGGCGRFF 708 G + +FTGDTLF+ GCGRFF Sbjct: 146 G-EQCIFTGDTLFIAGCGRFF 165 >UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; n=4; Legionella pneumophila|Rep: Hydroxyacylglutathione hydrolase GloB - Legionella pneumophila (strain Corby) Length = 254 Score = 86.2 bits (204), Expect = 7e-16 Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M + + A DNY++ +DK VDP E +++ + + L Sbjct: 1 MTILPISAFSDNYIWAFIDKIAGVLDCVDPGEAAPIIRFAQSNQLTLRTILLTHHHYDHI 60 Query: 454 GGNEDLIKERPGLIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG + LIK+ P VYG D+RI +T ++ ++G+L+ LF P HT+ HI Y+ Sbjct: 61 GGVDSLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYY- 119 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 P++G +F GDTLF GCGR F Sbjct: 120 -EPQKG---WLFCGDTLFSAGCGRVF 141 >UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase; n=1; Acinetobacter sp. ADP1|Rep: Putative hydroxyacylglutathione hydrolase - Acinetobacter sp. (strain ADP1) Length = 244 Score = 84.6 bits (200), Expect = 2e-15 Identities = 50/137 (36%), Positives = 72/137 (52%), Gaps = 3/137 (2%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 NY++++ D T+E +VDP E V + E+ V + GG DLI + Sbjct: 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLI-DGS 75 Query: 487 GLIVYGGDD---RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657 + VYG + +I +T ++H FK +LNV+ L TP HT GH+ YF+ E G+ Sbjct: 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFI--EETGS-- 131 Query: 658 VVFTGDTLFLGGCGRFF 708 +F GDTLF GCGR F Sbjct: 132 -LFCGDTLFAMGCGRVF 147 >UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; Mariprofundus ferrooxydans PV-1|Rep: Hydroxyacylglutathione hydrolase - Mariprofundus ferrooxydans PV-1 Length = 262 Score = 83.4 bits (197), Expect = 5e-15 Identities = 50/152 (32%), Positives = 71/152 (46%), Gaps = 2/152 (1%) Frame = +1 Query: 259 HQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXX 438 + + N V LP L+DNY+YLI A+ ++DP E +V +A E G L Sbjct: 4 YNHSNFTVHQLPVLKDNYIYLIEAHASSALIVIDPAEAVSVRRACRELGKPLTHIFNTHH 63 Query: 439 XXXXAGGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTG 612 GN+ L K+ +++ D RI + KV + + LN++ L HT G Sbjct: 64 HWDHTDGNQSLKKDFGAVVIGAAHDAERIPGINLKVSEASPPLVDGLNIRVLDVAGHTRG 123 Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 HI Y + D +F GDTLF GCGR F Sbjct: 124 HIAYLL-------DDALFCGDTLFGAGCGRLF 148 >UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: Glyoxalase II - Oryza sativa (Rice) Length = 336 Score = 83.4 bits (197), Expect = 5e-15 Identities = 49/149 (32%), Positives = 73/149 (48%), Gaps = 3/149 (2%) Frame = +1 Query: 271 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450 ++ ++++P LQDNY Y++ D T +VDP E ++ A+E++ NL Sbjct: 82 SLQIELVPCLQDNYAYILHDVDTGTVGVVDPSEATPIINALEKRNQNLTYILNTHHHYDH 141 Query: 451 AGGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621 GGN +L K + G V G DRI + + + V + TP HT+GH+C Sbjct: 142 TGGNLEL-KAKYGAKVIGSAKDRDRIPGIDITLSEGDTWMFAGHQVLVMETPGHTSGHVC 200 Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 Y P G +FTGDTLF CG+ F Sbjct: 201 YHF--PGSG---AIFTGDTLFSLSCGKLF 224 >UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; n=1; Limnobacter sp. MED105|Rep: Metallo-beta-lactamase family protein - Limnobacter sp. MED105 Length = 257 Score = 83.0 bits (196), Expect = 7e-15 Identities = 52/158 (32%), Positives = 75/158 (47%), Gaps = 4/158 (2%) Frame = +1 Query: 247 SQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXX 426 S + Q N V +PA QDNY++ IV + +K +VDP K+V + ++ G +L Sbjct: 3 SFKSSQVSNWSVYGIPAFQDNYLWAIVHEPSKACMVVDPGCSKSVQEFLDSHGYHLSGIL 62 Query: 427 XXXXXXXXAGGNEDLI-KERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPC 600 GG + L+ K L VYG RI + + V + L Q L P Sbjct: 63 VTHHHMDHVGGIDALLSKAGKDLPVYGPASGRIAQINRPVREGDTVDVHCLVAQVLEVPG 122 Query: 601 HTTGHICYFVTAPEEGN--DSVVFTGDTLFLGGCGRFF 708 HT H+ Y + + N ++ +F GDTLF GGCGR F Sbjct: 123 HTVDHLAYVIELKDTMNSEETWMFPGDTLFSGGCGRLF 160 >UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydrolase; n=7; Prochlorococcus marinus|Rep: Metallo-beta-lactamase superfamily hydrolase - Prochlorococcus marinus Length = 253 Score = 82.2 bits (194), Expect = 1e-14 Identities = 48/144 (33%), Positives = 72/144 (50%), Gaps = 4/144 (2%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +P L DN +++ V + K+A +VDP + V+ ++ G++L GG ++ Sbjct: 13 IPVLMDNIIWIWVKE--KQAIVVDPAISEPVINLLKGNGLSLHSVLQTHHHEDHIGGTQE 70 Query: 469 LIKERPGLIVYGGD---DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAP 639 LI P V DRI TK V N + I ++ + P HT+ HIC+F+ Sbjct: 71 LINVWPSASVIAAKSDLDRIQFQTKSVVDNEELDILGQKIKVIEVPGHTSNHICFFLQGS 130 Query: 640 EEGN-DSVVFTGDTLFLGGCGRFF 708 +E D V+F GDTLF GCGR F Sbjct: 131 KESKIDPVLFCGDTLFGAGCGRLF 154 >UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; n=9; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Methylococcus capsulatus Length = 256 Score = 81.8 bits (193), Expect = 2e-14 Identities = 48/148 (32%), Positives = 78/148 (52%), Gaps = 3/148 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +P L+DNY+YL+ + + A VDP VL+A++ +G L Sbjct: 2 LEILQIPVLEDNYVYLLHEPGSGATAAVDPAVAGPVLEALDARGWRLGHVLNTHHHGDHV 61 Query: 454 GGNEDLIKERPGLIVYG--GD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624 GGN +L K G V G GD RI + ++ +F++G+ + + L P HT+GH+ + Sbjct: 62 GGNLEL-KAATGCTVVGAAGDRHRIPGIDVALKDGEEFRLGSASARMLDVPGHTSGHVAF 120 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + +D+ +F GDTLF GCGR F Sbjct: 121 WFE-----DDAALFCGDTLFALGCGRLF 143 >UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase; n=40; Gammaproteobacteria|Rep: Probable hydroxyacylglutathione hydrolase - Escherichia coli O157:H7 Length = 251 Score = 81.8 bits (193), Expect = 2e-14 Identities = 49/147 (33%), Positives = 76/147 (51%), Gaps = 2/147 (1%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M++ +PA DNY++++ D+A + IVDP + + VL A+ Sbjct: 1 MNLNSIPAFDDNYIWVLNDEAGR-CLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHV 59 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKV--EHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 GG ++L+++ P ++VYG + T +V + T F +G+ + TP HT GHICYF Sbjct: 60 GGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGH-EFSVIATPGHTLGHICYF 118 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + +F GDTLF GGCGR F Sbjct: 119 -------SKPYLFCGDTLFSGGCGRLF 138 >UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily protein; n=7; Bacteria|Rep: Metallo-beta-lactamase superfamily protein - marine gamma proteobacterium HTCC2143 Length = 260 Score = 81.0 bits (191), Expect = 3e-14 Identities = 49/144 (34%), Positives = 73/144 (50%), Gaps = 1/144 (0%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459 ++ +PA DNY++ I D + +AA+VDP E V +A+ Q + L GG Sbjct: 4 IEPIPAFNDNYIWCIYDDDSGKAAVVDPGEAGPVEEALLAQQLQLETILITHHHFDHTGG 63 Query: 460 NEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636 E L K R + VYG + +I ++T +++ + + L+ L P HT HI + Sbjct: 64 IEALTKHR-DIPVYGPKNHQIASITHRLDEQSSMSLFGLDFTILEVPGHTLDHIALYCED 122 Query: 637 PEEGNDSVVFTGDTLFLGGCGRFF 708 G V+F GDTLF GGCGR F Sbjct: 123 TGTG-QPVLFCGDTLFAGGCGRIF 145 >UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent hydrolase, including glyoxylase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 270 Score = 79.0 bits (186), Expect = 1e-13 Identities = 49/146 (33%), Positives = 70/146 (47%), Gaps = 3/146 (2%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459 V+ +P L DNY+YL + A +DP + VL+ + +G L G Sbjct: 19 VEQIPVLSDNYVYLAHEPLGGATAAIDPAVSEPVLERLAARGWTLTHILNTHHHGDHTGA 78 Query: 460 NEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 N DL + R G V G +RI +T +V F +G+ V L P HT+GH+ Y++ Sbjct: 79 NLDLAR-RTGCAVVGAARDSERIPGITLEVSEGETFMLGHAAVTVLEVPGHTSGHVAYWL 137 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 + V+F GDTLF GCGR F Sbjct: 138 -----ADSHVLFCGDTLFSLGCGRLF 158 >UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Hydroxyacylglutathione hydrolase - Desulfuromonas acetoxidans DSM 684 Length = 249 Score = 78.6 bits (185), Expect = 1e-13 Identities = 50/145 (34%), Positives = 73/145 (50%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +L A DNY Y+I D T A +DP E + VL +E+ G +L Sbjct: 2 VEITLLQAHDDNYAYMISDGDTTIA--IDPGEAEPVLDYLEKHGRSLSLILNTHMHQDHC 59 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 GGN L K G + GGD+RI + + ++ ++ +Q + TP HT G CY++ Sbjct: 60 GGNLTL-KRLTGCHIAGGDERIVGVDRLLQEDSVLPGLPWPLQVMHTPGHTRGDCCYYLP 118 Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708 E +F GDTLF GGCGR F Sbjct: 119 QCE-----ALFCGDTLFSGGCGRVF 138 >UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione hydrolase-like isoform 2; n=1; Pan troglodytes|Rep: PREDICTED: hydroxyacylglutathione hydrolase-like isoform 2 - Pan troglodytes Length = 285 Score = 77.8 bits (183), Expect = 2e-13 Identities = 46/142 (32%), Positives = 69/142 (48%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M VK++P L+DNYMYL++++ T+EA VD PK V QG Sbjct: 1 MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRVRAGRGPQGPGRVPREPPRPLWQER 60 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 +++ + GG ALT +F G ++V+CL TP HT GH+ YF+ Sbjct: 61 SPTCSALRKS---LAAGGAPGPPALTGPPAPPPQF--GAIHVRCLLTPGHTGGHMSYFLW 115 Query: 634 APEEGNDSVVFTGDTLFLGGCG 699 + + +F+GD L + GCG Sbjct: 116 EDDCPDPPALFSGDALSVAGCG 137 >UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase with metallo- hydrolase/oxidoreductase domain; n=4; Proteobacteria|Rep: Putative hydroxyacylglutathione hydrolase with metallo- hydrolase/oxidoreductase domain - Pseudoalteromonas tunicata D2 Length = 261 Score = 77.0 bits (181), Expect = 4e-13 Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 3/148 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 + VK + A +DNY++ I++ + +VDP + + V+ + E + L Sbjct: 4 LQVKPIKAFKDNYIWAIINTENQHCVVVDPGDAEPVIAFISEHQLTLSAILITHHHWDHT 63 Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIG--NLNVQCLFTPCHTTGHICY 624 G E L + L VYG + +T+ + NT ++ +L+ L TP HT HICY Sbjct: 64 NGVEKLCSLQASLPVYGPKNSPFAGITEPLSANTVCQLTDFDLSFHILATPGHTLDHICY 123 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + E +F GDTLF GGCGR F Sbjct: 124 Y-----EPQQDWLFCGDTLFSGGCGRLF 146 >UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyoxylase - Ostreococcus tauri Length = 512 Score = 76.6 bits (180), Expect = 6e-13 Identities = 49/158 (31%), Positives = 70/158 (44%), Gaps = 18/158 (11%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +P + DNY YL+VD T+EA +DP +P+ + A G L AGGN Sbjct: 149 IPFMNDNYSYLVVDADTREACAIDPADPERAVDAARRCGAKLTTVLTTHKHHDHAGGNAR 208 Query: 469 ----LIKERPGLI---VYG-GDDRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHIC 621 + E G + VYG D+ T++V+ ++G L + PCHT GH+ Sbjct: 209 VRAMMALEENGSVDVEVYGHAMDKCHGTTREVKDGDVVRVGARLRFLVIHVPCHTLGHVV 268 Query: 622 YFVTAPEE---------GNDSVVFTGDTLFLGGCGRFF 708 Y + E N +FTGD + GG G FF Sbjct: 269 YALLGDEREDGADGPTLANAKAMFTGDAIINGGVGAFF 306 >UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase - Pseudomonas mendocina ymp Length = 257 Score = 74.9 bits (176), Expect = 2e-12 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQG-VNLXXXXXXXXXXXX 450 + + LPA DNY++L+ D ++ A+VDP + VL +E G L Sbjct: 2 IQIDALPAFNDNYIWLLQDPISRRCAVVDPGDAAPVLAWLEAHGDWTLSDILITHHHFDH 61 Query: 451 AGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG E L K + ++I A + N ++ L Q + P HT GHI Y+ Sbjct: 62 VGGVEQLKKATGARVAGPAAEKIPARDVDLGDNDLIEVLGLRFQIMAVPGHTLGHIAYY- 120 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 +++ GDTLF GGCGR F Sbjct: 121 ----HAEQNLLLCGDTLFAGGCGRLF 142 >UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mitochondrial precursor; n=12; core eudicotyledons|Rep: Hydroxyacylglutathione hydrolase 1, mitochondrial precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 331 Score = 74.9 bits (176), Expect = 2e-12 Identities = 45/146 (30%), Positives = 72/146 (49%), Gaps = 3/146 (2%) Frame = +1 Query: 271 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450 ++ ++++P +DNY YL+ D+ T +VDP E V++A+ + NL Sbjct: 77 SLKIELVPCSKDNYAYLLHDEDTGTVGVVDPSEAAPVIEALSRKNWNLTYILNTHHHDDH 136 Query: 451 AGGNEDLIKERPGLIVYGG---DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621 GGN +L KER G V G DRI + ++ + K+ V+ L TP HT GHI Sbjct: 137 IGGNAEL-KERYGAKVIGSAVDKDRIPGIDILLKDSDKWMFAGHEVRILDTPGHTQGHIS 195 Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCG 699 ++ + +FTGD ++ CG Sbjct: 196 FYFP-----GSATIFTGDLIYSLSCG 216 >UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; Proteobacteria|Rep: Hydroxyacylglutathione hydrolase - Pseudomonas stutzeri (strain A1501) Length = 292 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 2/145 (1%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE-EQGVNLXXXXXXXXXXXXAG 456 ++ LPA DNY++L+ D A + VDP + VL + G L G Sbjct: 37 IEALPAFTDNYIWLLQDDAARRCVAVDPGDAAPVLNWLSAHPGWQLSDILVTHHHHDHVG 96 Query: 457 GNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 G E L K + G VYG ++I A + + + ++ +Q + P HT GHI YF Sbjct: 97 GVERL-KAQTGARVYGPAAEKIPARDEALSDGQRIEVLGKRLQIIAVPGHTLGHIAYFHA 155 Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708 P++ + +GDTLF GCGR F Sbjct: 156 DPDQ---PWLLSGDTLFAAGCGRLF 177 >UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000658; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000658 - Rickettsiella grylli Length = 257 Score = 74.1 bits (174), Expect = 3e-12 Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 3/148 (2%) Frame = +1 Query: 274 MDVKILP--ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447 M +++LP A +DNY++ ++++ TK IVDP E K VL +++ + L Sbjct: 1 MTIQLLPILAFKDNYIWCLINEETKHCLIVDPGEAKPVLAQLKQLNLTLDALLITHHHWD 60 Query: 448 XAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNL-NVQCLFTPCHTTGHICY 624 G ++ P + ++I +T V K ++ + + + L P HT GHI Y Sbjct: 61 HTNGIRSILNHYPVPVFGPSKEKIVGVTHPVNETDKIELTHWPSFEILAIPGHTLGHIAY 120 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + GN ++F GDTLF GCGR F Sbjct: 121 Y------GN-HLLFCGDTLFTAGCGRLF 141 >UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putative; n=4; cellular organisms|Rep: Hydroxyacylglutathione hydrolase, putative - Caulobacter crescentus (Caulobacter vibrioides) Length = 249 Score = 73.7 bits (173), Expect = 4e-12 Identities = 44/139 (31%), Positives = 68/139 (48%), Gaps = 2/139 (1%) Frame = +1 Query: 298 LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIK 477 L DNY +L+ D+A+ + A +D + +L + + G +L AGGNE L K Sbjct: 11 LSDNYGFLVRDEASGKVATIDTPDAGAILAELAKLGWSLDLILNTHWHPDHAGGNETL-K 69 Query: 478 ERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651 G + G + RI L + V + +G+ + + T HT GH+ Y+ + Sbjct: 70 TATGATIVGPAEVTRIAPLDRVVRDGEEVMLGDTRLTVIDTGGHTLGHVSYY-----DAE 124 Query: 652 DSVVFTGDTLFLGGCGRFF 708 D++ F GDTLF GCGR F Sbjct: 125 DAIAFVGDTLFALGCGRLF 143 >UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; Marinomonas|Rep: Hydroxyacylglutathione hydrolase - Marinomonas sp. MWYL1 Length = 257 Score = 72.1 bits (169), Expect = 1e-11 Identities = 45/143 (31%), Positives = 64/143 (44%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M + LPA DNY+++I DK + VDP + VL E L Sbjct: 1 MTIFPLPAFNDNYIWIIQDKDSSGIWAVDPGKADVVLNFCHEYQKTLTGILITHHHKDHT 60 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 GG +L K+ VYG + +T V+ + + + + TP HT H+CYF Sbjct: 61 GGVAEL-KQHSNCPVYGPEHLTELVTHPVDDGDRILVFSKVFTVIATPGHTLDHLCYF-- 117 Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702 E ++ +GDTLF GGCGR Sbjct: 118 --SEQETPILLSGDTLFKGGCGR 138 >UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily protein; n=6; Bacteroidetes|Rep: Metallo-beta-lactamase superfamily protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 471 Score = 71.7 bits (168), Expect = 2e-11 Identities = 43/121 (35%), Positives = 61/121 (50%), Gaps = 1/121 (0%) Frame = +1 Query: 343 EAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519 EAAI+DP+ T L+ ++ GV L G+ DL + IVYG + Sbjct: 23 EAAIIDPLREITPYLERLKRDGVKLKYILETHFHADFVSGHLDLSRATGAPIVYGPTAKP 82 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 G E N F++GN+ ++ L TP HT C F+ E G ++ +F+GDTLFLG G Sbjct: 83 GFDAIVAEDNQIFELGNVKIRVLHTPGHTMESSC-FLLIDENGREAALFSGDTLFLGDVG 141 Query: 700 R 702 R Sbjct: 142 R 142 >UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX II) protein; n=1; alpha proteobacterium HTCC2255|Rep: Putative hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX II) protein - alpha proteobacterium HTCC2255 Length = 255 Score = 71.7 bits (168), Expect = 2e-11 Identities = 49/148 (33%), Positives = 64/148 (43%), Gaps = 2/148 (1%) Frame = +1 Query: 271 NMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450 ++ V I+P L DNY YLI + T A++D + +L + E G L Sbjct: 2 SLSVIIVPCLIDNYAYLIRCEETGHTAVIDVPDAYPILNMINELGWKLNSILITHHHSDH 61 Query: 451 AGGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624 G E L K ++ D R+ L V IGN + L TP HT GHI Y Sbjct: 62 VDGVEQLQKLTGANVIGAKSDSHRLPNLNISVSTGDVISIGNQQAEILNTPGHTIGHISY 121 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 F + VFTGD+L GCGR F Sbjct: 122 FFK-----DSKKVFTGDSLMSLGCGRLF 144 >UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; Psychromonas|Rep: Hydroxyacylglutathione hydrolase - Psychromonas ingrahamii (strain 37) Length = 256 Score = 70.9 bits (166), Expect = 3e-11 Identities = 46/146 (31%), Positives = 70/146 (47%), Gaps = 2/146 (1%) Frame = +1 Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 +V + A +DNY++LI D ++ IVDP + VL +E+Q + + G Sbjct: 3 NVITIKAFEDNYIWLIKDSQSQHCIIVDPGDAAPVLTILEDQKLIVDAILLTHHHYDHIG 62 Query: 457 GNEDLIKERPGLI-VYGGDDRIGALTKKVEHNT-KFKIGNLNVQCLFTPCHTTGHICYFV 630 G + L+ R I +Y E +T F G L++Q + P HT H+ ++ Sbjct: 63 GVDALLSARDEKISIYSKKKLFDRCRLVNESDTLSFFDGKLSLQVMEVPGHTLDHVAFY- 121 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 ND ++F GDTLF GGCGR F Sbjct: 122 ------NDELLFCGDTLFSGGCGRVF 141 >UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium japonicum Length = 255 Score = 70.5 bits (165), Expect = 4e-11 Identities = 48/147 (32%), Positives = 66/147 (44%), Gaps = 3/147 (2%) Frame = +1 Query: 277 DVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 +++ L DN+ YLI D TK A +D E +LKA+E +G L G Sbjct: 4 EIRTFSCLNDNFGYLIHDVETKATASIDAPEAGPILKALEREGWQLTDILITHHHGDHVG 63 Query: 457 GNEDLIKERPGLIVYGGDDRIGALTK---KVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 G +L K + V D+ A+ +V + K+GNL + + TP HT HI Y Sbjct: 64 GVAEL-KHKYNCRVVAPHDKTTAIANVDLRVANADVVKVGNLLARVVETPGHTLDHISYV 122 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + VF DTLF GCGR F Sbjct: 123 F-----DTEKTVFAADTLFSIGCGRVF 144 >UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; Marinobacter|Rep: Hydroxyacylglutathione hydrolase - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 263 Score = 70.5 bits (165), Expect = 4e-11 Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M + +PA DNY++ + + + + IVDP + K VL + + G + Sbjct: 1 MRIHPVPAFSDNYIWCLTNLESGKTLIVDPGQAKPVLDYLSDSGFSADTILITHHHPDHT 60 Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG ++L ++ P L + G D T V + + L P HT HI Y+ Sbjct: 61 GGVKELQQQYPDLRIVGPTDSPFKGATNTVHAGDEVVWEGITFNVLAVPGHTLDHIAYY- 119 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 + + + V+F GDTLF+ GCGR F Sbjct: 120 SDTQVNDKPVLFCGDTLFVCGCGRLF 145 >UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; n=2; Alteromonadales|Rep: Metallo-beta-lactamase family protein - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 265 Score = 70.1 bits (164), Expect = 5e-11 Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG 459 V + A DNY++ I + + A+VDP + +K ++E + L GG Sbjct: 8 VTAINAFNDNYIWAISSQNNDKIALVDPGDAVVCIKYLQENNLALSAILITHHHSDHVGG 67 Query: 460 NEDLI---KERPGLI-VYG-GDDRIGALTKKVEHNTKFKIGNLNVQ--CLFTPCHTTGHI 618 E L+ K++ + VYG ++I L ++ N + L+ Q L P HT GHI Sbjct: 68 IEKLLEYSKDKAWPVTVYGPATEKIAQLDITLKENDTVDLTELDCQFTVLDLPGHTKGHI 127 Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 Y+ ND +VF GDTLF GGCGR F Sbjct: 128 AYY-------NDKMVFCGDTLFSGGCGRLF 150 >UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55; Proteobacteria|Rep: Hydroxyacylglutathione hydrolase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 268 Score = 70.1 bits (164), Expect = 5e-11 Identities = 49/146 (33%), Positives = 66/146 (45%), Gaps = 6/146 (4%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +PA DNY++L+ D ++A VDP E V + + E+G L GG Sbjct: 9 VPAFDDNYIWLVSDG--RDAIAVDPGEAAPVRRVLAERGWRLTAILLTHHHADHVGGVAA 66 Query: 469 LIKERPG---LIVYG-GDDRIGALTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHICYFV 630 L +P L VYG + IG +T+ + + + L P HT GHI YF Sbjct: 67 LRDSQPDDAPLTVYGPAAEAIGVVTRPLSGGDRVTLDAPAATFDVLDVPGHTRGHIAYFQ 126 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 A + VF GDTLF GCGR F Sbjct: 127 AAGQGNAAPHVFCGDTLFSCGCGRLF 152 >UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyoxylases; n=1; Hahella chejuensis KCTC 2396|Rep: Zn-dependent Hydrolase, including glyoxylases - Hahella chejuensis (strain KCTC 2396) Length = 257 Score = 70.1 bits (164), Expect = 5e-11 Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 1/141 (0%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +PA DNY++ I +A +VDP + + VL+ + E + L GG + Sbjct: 7 IPAFNDNYIWSI-QSDQGDAWVVDPGDAQPVLRHLAENHLTLRGILITHHHHDHTGGVNE 65 Query: 469 LIKERPGLIVYGG-DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 L+ P + VYG I A+T ++ + +G+ +++ L TP HT HI YF + Sbjct: 66 LLANHP-VPVYGFMRSAIKAITVPLQEGDRVDLGDFSLEVLETPGHTLDHISYF---GDI 121 Query: 646 GNDSVVFTGDTLFLGGCGRFF 708 +F GDTLF GCGR F Sbjct: 122 AGAPRLFCGDTLFSAGCGRLF 142 >UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Neptuniibacter caesariensis|Rep: Metallo-beta-lactamase superfamily protein - Neptuniibacter caesariensis Length = 257 Score = 70.1 bits (164), Expect = 5e-11 Identities = 45/141 (31%), Positives = 64/141 (45%), Gaps = 1/141 (0%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +PA DNY+++I + A+VDP + VL +EE + L GG E Sbjct: 7 IPAFSDNYIWVIASPDSNMVAVVDPGDEAPVLAYLEENNLQLTAILITHHHNDHTGGVEA 66 Query: 469 LIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 L K+R VYG + +T + ++ +V P HT HI Y+ E Sbjct: 67 L-KDRFKTPVYGPANSPFQGITHPLNDGDSIQLMGASVAIKAIPGHTLDHISYY----SE 121 Query: 646 GNDSVVFTGDTLFLGGCGRFF 708 + +F GDTLFL GCGR F Sbjct: 122 RHKPQLFCGDTLFLAGCGRLF 142 >UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precursor; n=4; Proteobacteria|Rep: Hydroxyacylglutathione hydrolase precursor - Verminephrobacter eiseniae (strain EF01-2) Length = 258 Score = 70.1 bits (164), Expect = 5e-11 Identities = 44/146 (30%), Positives = 68/146 (46%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M++ LPA DNY++++ D A +VDP + V A+ G+ L Sbjct: 1 MNLLALPAFADNYLWMLHDG--HRAIVVDPGQAAPVADALRRLGLQLQAILVTHHHADHV 58 Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG E L + G V+G + + ++ + L ++ + P HT GHI Y+ Sbjct: 59 GGVEAL-RNATGASVHGPARESVPEPLVRLAQGDTVDVLGLRLEVIDVPGHTAGHIAYY- 116 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 P+ ++F GDTLF GGCGR F Sbjct: 117 -CPQMDGAPLLFCGDTLFSGGCGRLF 141 >UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 489 Score = 69.7 bits (163), Expect = 7e-11 Identities = 48/173 (27%), Positives = 75/173 (43%), Gaps = 2/173 (1%) Frame = +1 Query: 190 RITKLYFRALIRNQREAHSSQEDHQYKNM-DVKILPALQDNYMYLIVDKATKEAAIVDPV 366 +I + + + L +E Q + K +I Y Y I ++ KEA I+DP+ Sbjct: 18 KILQKFNKTLFHFSKEVQLKQSETLGKGFYQQQIFTGCLAEYAYYI--ESNKEAIIIDPL 75 Query: 367 EP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVE 543 + L +E+G + G+ L +E I+ G ++K + Sbjct: 76 RDIQPYLNIAKERGAKIKYVLLTHFHADFIAGHLSLQRETDAQIIMGPRATAPFISKVMN 135 Query: 544 HNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 N K+G + +Q L TP HT C F+ EEG ++TGDTLFLG GR Sbjct: 136 DNEFLKVGKVKIQALHTPGHTQESTC-FLLYDEEGKQHSIYTGDTLFLGEVGR 187 >UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putative; n=19; Bacteria|Rep: Hydroxyacylglutathione hydrolase, putative - Brucella suis Length = 257 Score = 68.5 bits (160), Expect = 2e-10 Identities = 47/150 (31%), Positives = 72/150 (48%), Gaps = 3/150 (2%) Frame = +1 Query: 268 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447 + ++++ DNY LI D + A +D + + A+E +G L Sbjct: 3 QRLEIEQFICRSDNYGVLIHDPESALTATIDAPDAYAIEAALERRGWTLDFIFTTHHHLD 62 Query: 448 XAGGNEDLIKERPGLIVYGGDD---RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHI 618 GNE L KE+ G+ + G + +I + + V+ +F G V+ + TP HT G I Sbjct: 63 HVEGNEPL-KEKFGVSIIGPEAEKAKIPGIDRTVKGGDEFTFGLFKVKVISTPGHTAGGI 121 Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 Y++ P+ VVFTGDTLF GCGR F Sbjct: 122 SYYL--PDA---KVVFTGDTLFALGCGRLF 146 >UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precursor; n=5; Sphingomonadaceae|Rep: Hydroxyacylglutathione hydrolase precursor - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 246 Score = 67.7 bits (158), Expect = 3e-10 Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 6/151 (3%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +P L DNY++L+ + A+ +VDP VL A + +G + Sbjct: 4 LEIVRIPVLSDNYVWLVHEPASGATMVVDPAVADPVLDAAKARGWAITDIWNTHWHPDHT 63 Query: 454 GGN---EDLIKERPGLIVYG---GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH 615 GGN ++ K G + G +RI L V+ ++G+ P HT GH Sbjct: 64 GGNAAIKEAAKAWGGCTITGPAAEHERIPTLDVLVKGGDTVRLGDHVADVWDVPAHTAGH 123 Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 I Y +D+ +F GDT+F GCGR F Sbjct: 124 IAYHF-----ADDAAIFVGDTMFAMGCGRLF 149 >UniRef50_Q581U6 Cluster: Hydroxyacylglutathione hydrolase, putative; n=1; Trypanosoma brucei|Rep: Hydroxyacylglutathione hydrolase, putative - Trypanosoma brucei Length = 464 Score = 67.7 bits (158), Expect = 3e-10 Identities = 55/173 (31%), Positives = 77/173 (44%), Gaps = 25/173 (14%) Frame = +1 Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE------EQGVNLXXXX 426 Y + V +P L DNY Y I+ TK A+VDP +P VL +E + + Sbjct: 129 YDGVFVMPVPVLLDNYAYFILSCKTKRCAVVDPADPTLVLNMLEVVRNLTQIDFMITDIL 188 Query: 427 XXXXXXXXAGGNEDL------IKER------PGLIVYGGD-DRIGALTKKVEHNTKFKI- 564 AGGN ++ ER P L +YG + DR A K ++ + + + Sbjct: 189 TTHKHWDHAGGNMEMRALSQCSSERCRALLSPELNIYGSEVDRPHACNKLIKGSDELVVA 248 Query: 565 -GNLNVQCLFTPCHTTGHICYFV--TAPEEGNDS--VVFTGDTLFLGGCGRFF 708 G V L TP HT G + + V P+EG +FTGD +F GGCG F Sbjct: 249 GGGAKVVVLSTPGHTGGSVMFLVGDALPKEGEPQRLALFTGDCVFCGGCGALF 301 >UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; Psychrobacter|Rep: Hydroxyacylglutathione hydrolase - Psychrobacter sp. PRwf-1 Length = 259 Score = 66.5 bits (155), Expect = 6e-10 Identities = 40/140 (28%), Positives = 63/140 (45%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +PA DNY++ +V+ K+A ++DP + + V +E+ G+ L GG + Sbjct: 8 IPAFTDNYIWALVNDTNKQAIVIDPGQAQPVADYLEQYGLELTAIWITHHHHDHVGGVAE 67 Query: 469 LIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 L + P V + + V+ + Q P HT H+ Y + +EG Sbjct: 68 LRELYPMTHVVASAEHGVKPDQVVKEGSSVSAWGYTAQVWAVPGHTQSHLAYVL--DKEG 125 Query: 649 NDSVVFTGDTLFLGGCGRFF 708 + VF GDTLF GCGR F Sbjct: 126 HKQ-VFCGDTLFSAGCGRVF 144 >UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrolase; n=2; Buchnera aphidicola|Rep: Probable hydroxyacylglutathione hydrolase - Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisumsymbiotic bacterium) Length = 251 Score = 66.5 bits (155), Expect = 6e-10 Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M +K + L DNY++++++ + I+DP + +++ +E + L Sbjct: 1 MILKKISILSDNYVWVLLN-TSGSCIIIDPGLSEPIIQEIERKKWRLRAILLTHNHIDHT 59 Query: 454 GGNEDLIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG +I+ P + V+G + R + K V H + + + FTP HT+GH+ Y+ Sbjct: 60 GGTRKIIEYFPKISVFGPKETRQHGVNKIVSHGDRIILLDKIFYVFFTPGHTSGHVSYY- 118 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 + +F GDTLF GCGR F Sbjct: 119 ------SQPYIFCGDTLFSAGCGRVF 138 >UniRef50_Q4RJI5 Cluster: Chromosome 3 SCAF15037, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 3 SCAF15037, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 227 Score = 65.3 bits (152), Expect = 1e-09 Identities = 29/47 (61%), Positives = 39/47 (82%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNL 414 M V++LPAL DNYMYL+VD ++EAA+VDPVEP V++AV++ GV L Sbjct: 49 MRVELLPALSDNYMYLLVDVESREAAVVDPVEPLKVVEAVKKHGVRL 95 >UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; Gluconobacter oxydans|Rep: Hydroxyacylglutathione hydrolase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 259 Score = 64.9 bits (151), Expect = 2e-09 Identities = 47/147 (31%), Positives = 72/147 (48%), Gaps = 4/147 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATK-EAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXX 450 +D+K +P L DNY +L+ AT+ + A+VDP E ++ + + +++ Sbjct: 24 LDIKPIPVLSDNYAWLLT--ATEGQRAVVDPGEAGPIMDEIGDGRLDMILLTHHHADHT- 80 Query: 451 AGGNEDLIKERPGLIVYGGDDR---IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621 AG D ++ER G VYG + + L VE +G+ ++ L TP H GH+ Sbjct: 81 AG--TDALRERYGAKVYGPRQKREWLPRLDHDVEDGDSLSLGSAQIRVLSTPGHAVGHVS 138 Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGR 702 Y V PE +F GD LF GCGR Sbjct: 139 YVV--PEV---PALFCGDVLFSLGCGR 160 >UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 493 Score = 64.5 bits (150), Expect = 2e-09 Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Frame = +1 Query: 331 KATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG 507 ++ KEA ++DP+ E + ++ +++G + G+ DL K+ IVYG Sbjct: 49 ESEKEAIVIDPLRETEPYIEYAKKRGATIKYILLTHFHADFISGHVDLAKKTGAKIVYGP 108 Query: 508 DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL 687 + K IG +N++ L TP HT CY + E VFTGDTLFL Sbjct: 109 TAKASFDFHLATDGEKIPIGKVNIEVLHTPGHTQESSCYLLLDGE--RQHAVFTGDTLFL 166 Query: 688 GGCGR 702 G GR Sbjct: 167 GEVGR 171 >UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; Pasteurellaceae|Rep: Hydroxyacylglutathione hydrolase - Mannheimia haemolytica PHL213 Length = 235 Score = 63.7 bits (148), Expect = 4e-09 Identities = 40/145 (27%), Positives = 66/145 (45%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 + + +PAL+DNY++ I + ++ I+DP E + L + + +NL Sbjct: 2 LQITPIPALKDNYIWAI--RNGQDVIIIDPSEHQPALNFIAKNALNLTAILITHNHHDHT 59 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 G ++++ P + VYG + V + +V+ + + HT GHI Y Sbjct: 60 DGVSGIVEQYPNIPVYGPQEVAEFANVIVSPEQHISLFGYDVRIIESGGHTAGHISYLF- 118 Query: 634 APEEGNDSVVFTGDTLFLGGCGRFF 708 G D +F GD LF GGCGR F Sbjct: 119 ----GYD-YLFCGDALFSGGCGRVF 138 >UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrolase GloB; n=1; Idiomarina baltica OS145|Rep: Probable hydroxyacylglutathione hydrolase GloB - Idiomarina baltica OS145 Length = 252 Score = 63.7 bits (148), Expect = 4e-09 Identities = 46/146 (31%), Positives = 65/146 (44%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M V + A DNY++LI + +VDP + K V++ ++ ++ Sbjct: 1 MRVHPVKAFDDNYIWLI-ESTQDRVVVVDPGDDKPVIEWLKANKKDIAGYLITHHHHDHT 59 Query: 454 GGNEDLIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG E L K R YG D+ I + V +I L L TP HT HI ++ Sbjct: 60 GGLEAL-KARFPATSYGPDNPAIKGIDYAVMEGDTVQIAGLRFDVLATPGHTLDHISFY- 117 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 D+ +F GDTLF GGCGR F Sbjct: 118 ------GDTALFCGDTLFSGGCGRMF 137 >UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putative; n=10; Chlorobiaceae|Rep: Hydroxyacylglutathione hydrolase, putative - Chlorobium tepidum Length = 215 Score = 63.3 bits (147), Expect = 6e-09 Identities = 45/132 (34%), Positives = 58/132 (43%), Gaps = 1/132 (0%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 N+ YL DKAT EA VDP PK ++ A +G L GNE+ + Sbjct: 15 NFGYLCADKATGEAFAVDPSNSPKVLVDAAARKGWQLVRAFCTHGHADHTNGNEEF-ERL 73 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 G+ V DR L +V H F +G V+ + TP HT IC + Sbjct: 74 TGIRVLLFGDRDARLGIEVMHGASFPLGEGVVEIIHTPGHTLDSICLLA-------GDAL 126 Query: 664 FTGDTLFLGGCG 699 FTGDTLF+G G Sbjct: 127 FTGDTLFVGKVG 138 >UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrolase; n=1; Oceanobacter sp. RED65|Rep: Probable hydroxyacylglutathione hydrolase - Oceanobacter sp. RED65 Length = 264 Score = 62.9 bits (146), Expect = 8e-09 Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 3/143 (2%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 LP ++ N Y + + + +VDP + + ++ + EQ ++L G D Sbjct: 7 LPIIEHNGNYAWIIEHAGKVTVVDPGDAQPIINHLREQDLDLDYILVTHKHWDHVNGILD 66 Query: 469 LIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV--TAP 639 + P +VYG G I L + ++ L+ + TP HT HI ++ T P Sbjct: 67 MKNAFPNAVVYGTGHADIPGLDHPILGGEPLELMGLSWKTWHTPGHTLDHIVFYTETTNP 126 Query: 640 EEGNDSVVFTGDTLFLGGCGRFF 708 E + +F+GD +F GCGR F Sbjct: 127 EGESQGHIFSGDNIFACGCGRMF 149 >UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; n=4; Alphaproteobacteria|Rep: Metallo-beta-lactamase family protein - Oceanicaulis alexandrii HTCC2633 Length = 255 Score = 62.9 bits (146), Expect = 8e-09 Identities = 44/147 (29%), Positives = 65/147 (44%), Gaps = 2/147 (1%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 ++++ P LQDNY +LI T A +D E +L+ + + A Sbjct: 3 LEIRQFPCLQDNYGFLIRCSETGATACIDTPEADVILEESQTLDWPIRAIWNTHHHWDHA 62 Query: 454 GGNEDLIKERPGLIVYGGDDR--IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 GGNE + + IV + IG + + V +GNL + + HT GH+ Y+ Sbjct: 63 GGNEAIRQATGARIVAPRAEAATIGHVDQPVAAGDAVALGNLTARVMDVGGHTLGHVAYW 122 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 EE V F GD+LF GCGR F Sbjct: 123 F---EEAG--VAFVGDSLFALGCGRMF 144 >UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrolase; n=2; Prochlorococcus marinus|Rep: Putative hydroxyacylglutathione hydrolase - Prochlorococcus marinus (strain AS9601) Length = 303 Score = 62.9 bits (146), Expect = 8e-09 Identities = 46/162 (28%), Positives = 70/162 (43%), Gaps = 3/162 (1%) Frame = +1 Query: 232 REAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVN 411 R HS+ K ++ L L DN ++L+ K ++DP + V++ + E + Sbjct: 50 RILHSNLTMEFNKARNIIGLRVLSDNVIWLMAKD--KSVVVIDPSVHEPVIRYINENNFH 107 Query: 412 LXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDD---RIGALTKKVEHNTKFKIGNLNVQ 582 L GG + LI++ P + V RI VE I V+ Sbjct: 108 LEAILQTHHHSDHIGGTKSLIEKWPNVKVIASSKEKKRIPFQNVSVEDGETLNILGEEVK 167 Query: 583 CLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + HT+ HI +F+ G + V+F GDTLF GGCGR F Sbjct: 168 IIEVLGHTSSHIAFFLN----GENPVLFIGDTLFSGGCGRIF 205 >UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Metallo-beta-lactamase family protein - Lentisphaera araneosa HTCC2155 Length = 222 Score = 62.5 bits (145), Expect = 1e-08 Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 6/139 (4%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI-K 477 DN++YLI DK T + A+VDP + + +A EE + G + ++ + Sbjct: 13 DNFIYLIKDKKTSDIAVVDPAWDVDAIFRAAEEMEGEIKEVFLTHSHYDHVNGVDQVLHR 72 Query: 478 ERPGLIVYGGDDRI--GA-LTKKVEHNTKF-KIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 L ++ +DR GA K+ F K+G++ ++ TP HT G +CY + Sbjct: 73 SDAKLHIHKIEDRFWGGAGRNAKLHSGGDFIKLGSIELKIHHTPGHTPGSVCYEL----- 127 Query: 646 GNDSVVFTGDTLFLGGCGR 702 D+ +FTGDT+F+ GCGR Sbjct: 128 --DNHLFTGDTVFVYGCGR 144 >UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precursor; n=44; Bacteria|Rep: Hydroxyacylglutathione hydrolase precursor - Polynucleobacter sp. QLW-P1DMWA-1 Length = 269 Score = 62.5 bits (145), Expect = 1e-08 Identities = 43/146 (29%), Positives = 69/146 (47%), Gaps = 6/146 (4%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +PA DNY++ I + K A +VDP + VL+ +++ G+ L GG Sbjct: 12 IPAFDDNYIWCIHNG--KSALVVDPGDAVPVLEYLKQSGLRLTGILITHHHADHTGGILA 69 Query: 469 LI----KERPGLIVYGGDDRIGALTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHICYFV 630 L+ K+ P ++ I T+ + + K +I + +++Q P HT HI YF Sbjct: 70 LLDALGKDIP--VIGPAGSNIPGRTQIAKADDKIEITSPRISLQVYEVPGHTLSHIAYFA 127 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 + ++F GDTLF GCGR F Sbjct: 128 NMQANVVEPMLFCGDTLFASGCGRLF 153 >UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain protein - Geobacter uraniumreducens Rf4 Length = 233 Score = 61.7 bits (143), Expect = 2e-08 Identities = 42/151 (27%), Positives = 67/151 (44%), Gaps = 6/151 (3%) Frame = +1 Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXX 441 Y+ ++I NY Y+I+D+ + EAAIVDP L+ ++E G Sbjct: 13 YQVFPLRICYQFMINYCYIILDRFSGEAAIVDPAWDLEALQGKLQEMGARPTMILLTHSH 72 Query: 442 XXXAGGNEDLIKERPGLIVYGGDDRIGALTK-----KVEHNTKFKIGNLNVQCLFTPCHT 606 L++E ++ +R EH + ++G + CL TP HT Sbjct: 73 YDHVNLVAPLVREYDPKVILSRQERDYYQFSCDNLFAAEHLDQIRLGETLINCLLTPGHT 132 Query: 607 TGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 TG +CY ++ +FTGDT+F+ GCG Sbjct: 133 TGSMCYLLS-------HSLFTGDTVFVEGCG 156 >UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione hydrolase - Magnetococcus sp. (strain MC-1) Length = 254 Score = 61.7 bits (143), Expect = 2e-08 Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 2/147 (1%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 ++V LPA +DNY++ + A+VDP + + V +++ G+ L Sbjct: 5 LEVTPLPAWEDNYIWCFPTEPGA-VAVVDPGQAEPVTDYLQQHGLRLSHILLTHHHGDHI 63 Query: 454 GGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 G L ++ ++ D R+ L + + F +G V TP HT+GH+CY Sbjct: 64 DGVAPLQRKHHARVLGSALDAHRLPPLDEALRGGQTFCLGPHQVDTYHTPGHTSGHLCYH 123 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + +F GDTLF GCGR F Sbjct: 124 IA-------DCLFAGDTLFSYGCGRLF 143 >UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrolase; n=1; Buchnera aphidicola (Baizongia pistaciae)|Rep: Probable hydroxyacylglutathione hydrolase - Buchnera aphidicola subsp. Baizongia pistaciae Length = 249 Score = 61.7 bits (143), Expect = 2e-08 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 1/144 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M + L DNY++++ + ++K+ I+DP E +V+K +++ +N Sbjct: 1 MKIIFTKVLFDNYVWIMFN-SSKDCIIIDPGESNSVIKKIKKLNLNPKIILLTHNHLDHI 59 Query: 454 GGNEDLIKERPGLIVYGGDDRIGALTKK-VEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 G ++L+ + P + +YG + TK +++ +I N + TP HT GH Y+ Sbjct: 60 QGVKNLLYKYPEISIYGPLETQFCGTKNLIDNRNTIEILNTKFYIIPTPGHTNGHTAYYC 119 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGR 702 +F GD++F GGCGR Sbjct: 120 PP-------FLFCGDSIFSGGCGR 136 >UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase; n=1; Plesiocystis pacifica SIR-1|Rep: Probable hydroxyacylglutathione hydrolase - Plesiocystis pacifica SIR-1 Length = 270 Score = 61.3 bits (142), Expect = 2e-08 Identities = 48/149 (32%), Positives = 69/149 (46%), Gaps = 9/149 (6%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 +P DN+ +L+V +AT EAA +D + VL+ VE G+ L G ++ Sbjct: 1 MPFWTDNFTWLLVCEATGEAAAIDGGVAEPVLEYVEAHGLRLTTILTTHTHPDHIGLHKA 60 Query: 469 LIK-ERPG-LIVYGGDDRIGALT-------KKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621 L K ER G L V G R+G + + V+ ++G L Q + T H GH+ Sbjct: 61 LDKAERLGALRVVGSRSRLGTIPGLDGPKGEPVDEGDVVRLGALEGQVMLTEGHIDGHVS 120 Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 Y ++F GDTLF GGCG F Sbjct: 121 YRF-------GELLFCGDTLFAGGCGYLF 142 >UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas aromatica RCB|Rep: Beta-lactamase-like - Dechloromonas aromatica (strain RCB) Length = 265 Score = 60.9 bits (141), Expect = 3e-08 Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +PA +DNY++L+ K A +VDP + VL +E G+ L Sbjct: 2 LEISFIPAFKDNYIWLLT--RGKRAFVVDPGDAAPVLARLEAGGLMLEGILITHHHADHQ 59 Query: 454 GGNEDLIKERPGLIVYG-GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG +L K R VY G++ I + + + V + P HT GH+ Y+ Sbjct: 60 GGVAEL-KARWQAEVYAPGNESITGCSCPLSGGESIDVLGQKVTVMAVPGHTLGHLAYY- 117 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 AP + GDTLF GCGR F Sbjct: 118 -AP-----GALLCGDTLFGAGCGRLF 137 >UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase - Moritella sp. PE36 Length = 258 Score = 60.9 bits (141), Expect = 3e-08 Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 4/147 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 ++V +P DNY++LI + IVDP + VL+ + +Q + L Sbjct: 2 LEVISIPTFNDNYVWLIKNTENNHCCIVDPGQADPVLQVINQQNLILEAILITHHHYDHI 61 Query: 454 GGNEDLIKERPGLI-VYGG-DDRIGALTKKVEHNTKFKIGN--LNVQCLFTPCHTTGHIC 621 G D++ + VY + A V N++ + N L + + TP H H+ Sbjct: 62 DGISDILNASTNPVQVYSSIAIDVDAPVTLVTENSQLNLLNNSLALTVMATPGHKREHVV 121 Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGR 702 Y+ N +++F+GDTLF GGCGR Sbjct: 122 YY-------NQTMLFSGDTLFSGGCGR 141 >UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; Clostridium|Rep: Hydroxyacylglutathione hydrolase - Clostridium tetani Length = 201 Score = 60.5 bits (140), Expect = 4e-08 Identities = 42/160 (26%), Positives = 75/160 (46%), Gaps = 17/160 (10%) Frame = +1 Query: 274 MDVKILPA-LQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXX 447 M++K +P + Y+++DK +KE IVDP E +L+ V + + Sbjct: 1 MELKRIPVGMYQANCYILMDKKSKEGIIVDPGDEANLILQTVNKMDCKVKYILLTHGHVD 60 Query: 448 XAGGNEDL---------IKERP------GLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQ 582 +++ I E+ G+ ++G GA K++ FKIG+ ++ Sbjct: 61 HVSAVKEVKDSLKAPVGINEKDEESILKGMDLFGNSQTCGAADIKIKEGDTFKIGDKEIK 120 Query: 583 CLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 C+ TP H+ G +C+ + ++++FTGDTLF G GR Sbjct: 121 CIETPGHSLGGMCFLI-------ENIIFTGDTLFEGSIGR 153 >UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily protein precursor; n=1; Thiomicrospira crunogena XCL-2|Rep: Metallo-beta-lactamase superfamily protein precursor - Thiomicrospira crunogena (strain XCL-2) Length = 268 Score = 60.5 bits (140), Expect = 4e-08 Identities = 45/148 (30%), Positives = 67/148 (45%), Gaps = 3/148 (2%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKAT--KEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447 M + LP L DNY ++I + K A IVDP E + V+ EE + L Sbjct: 1 MKIVGLPTLSDNYTWVIQSENADDKRAWIVDPGESQKVIHYFEENQLQLDGILLTHHHYD 60 Query: 448 XAGGNEDLIKERPGL-IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICY 624 G ++ + IV +T V+ + ++ N Q + TP HT HIC+ Sbjct: 61 HTDGIMGVMDALGEVAIVSNAQGPFKPVTHPVKEGDQVQVLNETFQVIETPGHTDEHICF 120 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + PE +F+GDTLF GGCG+ + Sbjct: 121 Y--HPE-----ALFSGDTLFTGGCGKIW 141 >UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione hydrolase GloB; n=1; Methylophilales bacterium HTCC2181|Rep: putative hydroxyacylglutathione hydrolase GloB - Methylophilales bacterium HTCC2181 Length = 223 Score = 59.7 bits (138), Expect = 7e-08 Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 3/138 (2%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 DNY++LI D + AIVDP + K V+ ++ + GG + + Sbjct: 2 DNYIWLIKD--CRNVAIVDPGDAKPVIDYLKSNDLYPKAILITHKHYDHIGGVVGIKLQY 59 Query: 484 PGLIVYGGDDRIGALTKKV-EHNTKFKIGNLNVQC--LFTPCHTTGHICYFVTAPEEGND 654 PG+ +YG V E + I ++++ L TP HT HI Y+ ND Sbjct: 60 PGVKIYGPKISSFDFDYTVLEEGSTLSIEGIDIKLNVLETPGHTDDHIAYY-------ND 112 Query: 655 SVVFTGDTLFLGGCGRFF 708 V+F GDTLF GCGR F Sbjct: 113 EVLFCGDTLFACGCGRLF 130 >UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putative; n=4; Rhodobacteraceae|Rep: Hydroxyacylglutathione hydrolase, putative - Silicibacter pomeroyi Length = 255 Score = 59.7 bits (138), Expect = 7e-08 Identities = 42/147 (28%), Positives = 63/147 (42%), Gaps = 2/147 (1%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +P L DNY YLI D + A+VD E + ++ +G +L Sbjct: 3 LEIVTVPCLSDNYAYLIHDADAGKTALVDAPEAAPIQSELDRRGWSLDQVWLTHHHWDHV 62 Query: 454 GGNEDL-IKERPGLIVYGGD-DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 G L + +P +I D R+ L V +F +G V+ L HT GHI + Sbjct: 63 DGLAALRDRYKPTVIGAEADAHRLPPLDLAVSEGDRFDLGGAPVEVLDVSGHTVGHIAFH 122 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + VFT D+L GCGR F Sbjct: 123 LP-----TGKAVFTADSLMALGCGRLF 144 >UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organisms|Rep: ENSANGP00000000940 - Anopheles gambiae str. PEST Length = 248 Score = 59.7 bits (138), Expect = 7e-08 Identities = 40/133 (30%), Positives = 57/133 (42%), Gaps = 2/133 (1%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y YL+ D TKEA ++DPV + K + ++E G L G L + Sbjct: 28 YSYLLADITTKEAILIDPVLEQAKRDAQLIKELGFTLKYALNTHMHADHVTGTGFLKQLL 87 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 PG + K + N + G ++ + TP HT G C E+G + Sbjct: 88 PGTVSVISQSSGAKADKHLVDNETVQFGRHELRAMSTPGHTNG--CMTFLVEEQG---IA 142 Query: 664 FTGDTLFLGGCGR 702 FTGDTL + GCGR Sbjct: 143 FTGDTLLIRGCGR 155 >UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9; Xanthomonadaceae|Rep: Hydroxyacylglutathione hydrolase - Xylella fastidiosa Length = 258 Score = 59.3 bits (137), Expect = 9e-08 Identities = 43/141 (30%), Positives = 66/141 (46%), Gaps = 1/141 (0%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 LPA +NY++ ++ + A IVDP + +L+A +G+ GG + Sbjct: 6 LPAFDNNYIWTLIAPDGR-AIIVDPGQALPILEA-HSKGLIPTAILLTHHHADHIGGVPE 63 Query: 469 LIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 L++ P L +Y D RI ++ I L Q + TP HT H+ + Sbjct: 64 LLERWPTLPIYAPHDTRIALNYHRIGEGDSLNILGLRFQVIHTPGHTHSHLTFI------ 117 Query: 646 GNDSVVFTGDTLFLGGCGRFF 708 GND ++F GDTLF GCG+ F Sbjct: 118 GND-LLFCGDTLFSLGCGQIF 137 >UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; Thiobacillus denitrificans ATCC 25259|Rep: Hydroxyacylglutathione hydrolase - Thiobacillus denitrificans (strain ATCC 25259) Length = 256 Score = 59.3 bits (137), Expect = 9e-08 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 3/143 (2%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 LPA +DNY+++ D K A VDP +P + ++ +G+ L GGN Sbjct: 7 LPAFEDNYIWVWHD--AKYAVAVDPGDPAVLSTYLDSRGLALAAVLVTHHHRDHTGGNTW 64 Query: 469 LIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQC--LFTPCHTTGHICYFVTAP 639 L ++R +Y D+ RI A++ V + L + L TP HT H+ Y Sbjct: 65 L-RQRYNCAIYAPDNPRIPAVSHVVRGGDSVAVPELGLALAVLATPGHTLDHVSYV---- 119 Query: 640 EEGNDSVVFTGDTLFLGGCGRFF 708 GN + F GDTLF GCG+ F Sbjct: 120 --GNGHL-FCGDTLFGCGCGKLF 139 >UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; n=1; Beggiatoa sp. PS|Rep: Metallo-beta-lactamase family protein - Beggiatoa sp. PS Length = 229 Score = 59.3 bits (137), Expect = 9e-08 Identities = 38/139 (27%), Positives = 65/139 (46%), Gaps = 6/139 (4%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 +N++YLI D + A+VDP E ++ + QG+ + G +L+ Sbjct: 19 ENFIYLIQDHHSNRTAVVDPAWEVPKIIALAQHQGLQITDVLLTHSHHDHTNGLTELLNS 78 Query: 481 RPGLI-VYGGDDRIGA--LTKKVEHNTK--FKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 + + +++ A LTK H+ ++G +++ TP HT G CY++ Sbjct: 79 YDAQVHLLKAEEQFWAHELTKPTVHHGSDTIQLGKTDIEIWHTPGHTPGSACYYL----- 133 Query: 646 GNDSVVFTGDTLFLGGCGR 702 D + TGDTLF+ GCGR Sbjct: 134 --DGHLITGDTLFIFGCGR 150 >UniRef50_Q4DNS9 Cluster: Putative uncharacterized protein; n=3; Trypanosoma cruzi|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 536 Score = 59.3 bits (137), Expect = 9e-08 Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 26/174 (14%) Frame = +1 Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPK------TVLKAVEEQGVNLXXXX 426 Y+ + V +P L DNY YLI+ ATK+ A+VDP +PK TV++ + L Sbjct: 200 YRGVAVVPVPLLADNYAYLILSFATKKCAVVDPADPKLVMYMLTVVRYLTGVEFVLTDIL 259 Query: 427 XXXXXXXXAGGNEDLIKERPG-------------LIVYGGD-DRIGALTKKVEHNTKFKI 564 AGGN + ++ L +YG D A T VE + Sbjct: 260 TTHKHWDHAGGNLEFMQHLQNKSDAEITELLDAQLKIYGSAIDNPHACTNFVEDGNVLTV 319 Query: 565 --GNLNVQCLFTPCHTTGHICYFVTAPEEGND----SVVFTGDTLFLGGCGRFF 708 G + V +P HT G + + + +D +FTGD +F GGCG F Sbjct: 320 AGGGVTVAVFSSPGHTVGSVMFLLGDALMDSDVPQRLALFTGDCIFCGGCGAMF 373 >UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprotei|Rep: Zn-dependent hydrolase - Cenarchaeum symbiosum Length = 203 Score = 59.3 bits (137), Expect = 9e-08 Identities = 43/145 (29%), Positives = 66/145 (45%), Gaps = 2/145 (1%) Frame = +1 Query: 274 MDVKILPALQ-DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXX 447 M V LP Q N+ Y++ D+ T + A++DP + TV++ V G++ Sbjct: 1 MKVHQLPVGQMQNFCYVVSDEETGKCAVIDPSWDLDTVMETVTRNGLSAEYVINTHHHFD 60 Query: 448 XAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 GNE I R G + ++ V ++ +IG+ + L TP H+ IC Sbjct: 61 HTVGNE-AIAGRTGARIIQHEESELKHDITVRDGSEIRIGSTMLSVLHTPGHSRDSICLV 119 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGR 702 D +FTGDTLF+G CGR Sbjct: 120 -------GDGKIFTGDTLFVGSCGR 137 >UniRef50_UPI0000E4A799 Cluster: PREDICTED: similar to CG4365-PC, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to CG4365-PC, partial - Strongylocentrotus purpuratus Length = 68 Score = 58.8 bits (136), Expect = 1e-07 Identities = 28/58 (48%), Positives = 40/58 (68%), Gaps = 1/58 (1%) Frame = +1 Query: 205 YFRALIRNQ-REAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPK 375 + + ++R Q R HS+ +M + +L AL+DNYMYL+ D+ATKEAAIVDPV P+ Sbjct: 10 HIQTVLRPQLRLCHSASTVTSLPDMKITLLSALEDNYMYLLTDEATKEAAIVDPVNPE 67 >UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaproteobacteria|Rep: Zn-dependent hydrolase - Francisella tularensis subsp. novicida (strain U112) Length = 228 Score = 58.8 bits (136), Expect = 1e-07 Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPVE--PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y Y++ + T++A I+D V LK ++E + L L KE Sbjct: 14 YTYILACEQTRQAVIIDSVRFNVNQYLKLLKELDLKLIYAIDTHVHADHVTAAGILRKET 73 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 IV GG+ + TKKV + GN ++ L+TP HT C F+T ++++ Sbjct: 74 GCDIVIGGESKAECATKKVFDGDILEFGNYQLKALYTPGHTDDSYC-FIT------ENML 126 Query: 664 FTGDTLFLGGCGR 702 FTGDTL + G GR Sbjct: 127 FTGDTLLIRGSGR 139 >UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2; Acetobacteraceae|Rep: Hydroxyacylglutathione hydrolase - Acidiphilium cryptum (strain JF-5) Length = 243 Score = 58.4 bits (135), Expect = 2e-07 Identities = 42/150 (28%), Positives = 59/150 (39%), Gaps = 2/150 (1%) Frame = +1 Query: 265 YKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXX 444 ++ + +P L DNY +L+ +A VDP + ++AVE G L Sbjct: 5 HRGFTITRVPMLADNYAWLVAHGGA--SAFVDPADAAAAIEAVEAAGGRLDWVLLTHHHD 62 Query: 445 XXAGGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHI 618 G DL I D R+ L + +G V+ + TP HT GH+ Sbjct: 63 DHIAGAVDLAARFGARIAGNAADAARLPRLDAALAPGQTIDLGGEAVRMIATPGHTVGHV 122 Query: 619 CYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 Y D+ GDTLF GCGR F Sbjct: 123 TYLF------GDAAAACGDTLFSLGCGRMF 146 >UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 538 Score = 58.0 bits (134), Expect = 2e-07 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 1/133 (0%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 +Y Y I ++ EAAI+DP+ E K +G + G+ L + Sbjct: 95 SYTYYI--ESNGEAAIIDPLRETKPYTDLAARRGAKIKYILESHFHADFVSGHISLANKT 152 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 I+YG + + + ++GN+ +Q L TP HTT C F+ + V Sbjct: 153 GAKIIYGPGAQALYDIHVAKDGEEIQLGNIKLQVLHTPGHTTESSC-FLLKDSKNQPHSV 211 Query: 664 FTGDTLFLGGCGR 702 +TGDTLFLG GR Sbjct: 212 YTGDTLFLGEVGR 224 >UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; n=14; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Shewanella oneidensis Length = 267 Score = 57.2 bits (132), Expect = 4e-07 Identities = 45/155 (29%), Positives = 64/155 (41%), Gaps = 10/155 (6%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 + + + A DNY++++ + +VDP + VL + + L Sbjct: 2 LTITAINAFNDNYIWVLQQDTQQAVYVVDPGDVNVVLDYLNAHQLTLAGILITHHHRDHT 61 Query: 454 GGNEDLI---KERPG--LIVYGGDDRI--G---ALTKKVEHNTKFKIGNLNVQCLFTPCH 603 GG L+ ++ G L VYG G A+ ++ N VQ L P H Sbjct: 62 GGIAALVAYVEQTTGHTLAVYGPQSEAIQGVNIAIEPQITQILHLPFLNSPVQVLSVPGH 121 Query: 604 TTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 T GHI Y V D +F GDTLF GGCGR F Sbjct: 122 TAGHIAYLV-------DGALFCGDTLFSGGCGRLF 149 >UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; n=14; Bacteria|Rep: Metallo-beta-lactamase domain protein - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 238 Score = 57.2 bits (132), Expect = 4e-07 Identities = 43/143 (30%), Positives = 64/143 (44%), Gaps = 3/143 (2%) Frame = +1 Query: 283 KILPALQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 ++ A Y YLI D AT+EAA+VDPV + + LK + E G+ L Sbjct: 5 QLFDAETSTYTYLIADPATREAALVDPVLEQVERDLKLIRELGLTLKYCLETHVHADHIT 64 Query: 457 GNEDLIKERPGLI-VYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 G L +E G V + + + H ++G++ ++ + T HT H+ Y V Sbjct: 65 GTGKL-RELTGCQGVVPVQAKAQCADRFIGHGETLQVGSVVIEAIATLGHTDSHMTYRV- 122 Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702 N V TGD L + GCGR Sbjct: 123 -----NGDRVLTGDALLIRGCGR 140 >UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily hydrolase; n=8; Cyanobacteria|Rep: Metallo-beta-lactamase superfamily hydrolase - Synechococcus sp. (strain CC9311) Length = 260 Score = 57.2 bits (132), Expect = 4e-07 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 5/142 (3%) Frame = +1 Query: 298 LQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIK 477 L DN +++ V +A ++DP +L ++ +G+ L GG L++ Sbjct: 22 LNDNIVWVWV--RGNQAIVIDPAVAAPILDWLDRRGLQLVAVLQTHHHSDHIGGTPGLLQ 79 Query: 478 ERPGL-IVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 ++ DD RI T V + ++ V+ + HT HI Y++ E Sbjct: 80 RWSSAEVIAAADDKERIPFQTLSVRDGDEIELLGRPVRVMDVRAHTRAHIAYWLPQGEIS 139 Query: 649 ND--SVVFTGDTLFLGGCGRFF 708 SV+F GDTLF GGCGR F Sbjct: 140 TSLTSVLFCGDTLFSGGCGRLF 161 >UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 617 Score = 56.0 bits (129), Expect = 9e-07 Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 1/139 (0%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNE 465 LP L +Y YL++ + KEA +VDP T L ++ G+ + G+ Sbjct: 5 LPVLS-HYSYLLI--SGKEALLVDPDRDITAYLDHAKKHGLTIKGVFLTHSHADFVAGHL 61 Query: 466 DLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 +L++ + + ++ + FK+G V+ + TP HT +C V + + Sbjct: 62 ELVRALNVPVYQNAASGAKYKIEPLKEGSTFKVGAAMVKAVETPGHTPDGMCGLVFSEGD 121 Query: 646 GNDSVVFTGDTLFLGGCGR 702 ++FTGDTLF+G GR Sbjct: 122 DQPKMIFTGDTLFVGSVGR 140 >UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of metallo-beta-lactamase superfamily; n=1; Clostridium acetobutylicum|Rep: Predicted Zn-dependent hydrolase of metallo-beta-lactamase superfamily - Clostridium acetobutylicum Length = 199 Score = 55.6 bits (128), Expect = 1e-06 Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 14/143 (9%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y++VD+ + E+ ++DP + P+ +L+A ++ NL +L KE Sbjct: 16 YILVDEKSNESVVIDPGDAPQAILEAFKDTETNLKFVLLTHGHADHTAAVAELKKEYNVD 75 Query: 493 IVYGGD-------------DRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 + D D+ TK V+ + + G L ++C+ TP HT G +CY V Sbjct: 76 VYMNKDDCKLIENGEYMFGDKSENATKYVDDGDELQFGELKIKCIKTPGHTPGGMCYLV- 134 Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702 D+ +F+GDTLF GR Sbjct: 135 ------DNYLFSGDTLFNSSIGR 151 >UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Thiomicrospira crunogena XCL-2|Rep: Metallo-beta-lactamase superfamily protein - Thiomicrospira crunogena (strain XCL-2) Length = 229 Score = 55.6 bits (128), Expect = 1e-06 Identities = 43/134 (32%), Positives = 62/134 (46%), Gaps = 3/134 (2%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPVEPKTVL--KAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y YL+ D+ TKEAA++D V K + ++E G+N+ G L K Sbjct: 14 YTYLLWDETTKEAAVIDSVLEKVDRDEQHIKELGLNVKYLLETHIHADHITGAGPLRKRM 73 Query: 484 PG-LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 G L+V+ A V+ + FK+G+ + L TP HT I Y + + Sbjct: 74 GGQLVVHKNSGSECADILAVDGDV-FKLGDQEIHVLHTPGHTNNDITYQI-------EGA 125 Query: 661 VFTGDTLFLGGCGR 702 VFTGDTL + CGR Sbjct: 126 VFTGDTLMVRDCGR 139 >UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; Rhodobacterales|Rep: Hydroxyacylglutathione hydrolase - Silicibacter sp. (strain TM1040) Length = 271 Score = 55.6 bits (128), Expect = 1e-06 Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 7/152 (4%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +P L DNY YL+ K A++D E + +L A+E + +L Sbjct: 17 LEIVTVPCLADNYAYLV--KGPDGVALIDAPEAEPILTALEARDWSLGVIMITHHHHDHV 74 Query: 454 GGNEDLIKERPGLIVYGGD---DRIGA--LTKKVEHNTKFKIGNLNVQC--LFTPCHTTG 612 GG L +E+ G V G D+I A +T +E F+ G +C L P HT G Sbjct: 75 GGVAAL-REKFGCPVMGPKAEADKIAAQGVTLDMELEPGFEGGTGAGRCQVLAVPGHTLG 133 Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 HI ++ PE +F+ D+L + GCGR F Sbjct: 134 HIAFYY--PEA---PALFSADSLMVMGCGRLF 160 >UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; cellular organisms|Rep: Hydroxyacylglutathione hydrolase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 263 Score = 55.6 bits (128), Expect = 1e-06 Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 3/134 (2%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 N+ YLI T EA +DP++ + L +G + GGN +I Sbjct: 14 NFNYLIACPETGEALAIDPLDHEKTLATARVKGWQITQVLNTHEHHDHTGGNAAVIAATG 73 Query: 487 GLIV--YGGDDRIGALTKKVEHNTKFKIG-NLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657 ++ + RI + + V+ K+G + ++CL TP HT HIC Sbjct: 74 AKLIAHHKAGGRIAGVDRGVKAGDVIKVGKTVELECLDTPGHTMCHIC----LRSHTEQP 129 Query: 658 VVFTGDTLFLGGCG 699 +F+GDTLF G G Sbjct: 130 ALFSGDTLFNAGAG 143 >UniRef50_Q0RV06 Cluster: Possible hydrolase; n=11; Actinomycetales|Rep: Possible hydrolase - Rhodococcus sp. (strain RHA1) Length = 496 Score = 55.6 bits (128), Expect = 1e-06 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 1/130 (0%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YLI D++T A +VDP T L G+ + G+ +L++ Sbjct: 53 YLIGDESTGRAVVVDPRRDITEYLDDARTHGLTIDGVINTHFHADFVSGHLELVEATGAW 112 Query: 493 IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 672 I +G +++ H +G ++++ L TP HT I + + + + V TG Sbjct: 113 IGFGEAAETDYPIRRLAHGEHISLGRVDLEILSTPGHTWESISVLIRETPDADPTAVLTG 172 Query: 673 DTLFLGGCGR 702 D+LF+G GR Sbjct: 173 DSLFIGDVGR 182 >UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrolase; n=1; Sodalis glossinidius str. 'morsitans'|Rep: Putative hydroxyacylglutathione hydrolase - Sodalis glossinidius (strain morsitans) Length = 250 Score = 54.8 bits (126), Expect = 2e-06 Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 1/146 (0%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 M++ +PAL DNY++L+ + + +VDP + VL+A+ + + Sbjct: 1 MNLISIPALADNYIWLLHND-DRRCLVVDPGDATPVLQALADHRLTPVAVLLTHHHQDHV 59 Query: 454 GGNEDLIKERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 GG +L++ P + VYG ++ R T+ V + + + P HT GHI ++ Sbjct: 60 GGVSELLQHFP-VPVYGPEETRSKGATQIVNEGDSLTLLDHTFSIMALPGHTLGHIGFY- 117 Query: 631 TAPEEGNDSVVFTGDTLFLGGCGRFF 708 +AP +F GDT+F G GR F Sbjct: 118 SAP------WLFCGDTVFSAGSGRLF 137 >UniRef50_A5INW0 Cluster: Beta-lactamase domain protein; n=30; Staphylococcus|Rep: Beta-lactamase domain protein - Staphylococcus aureus subsp. aureus JH9 Length = 444 Score = 54.8 bits (126), Expect = 2e-06 Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 11/140 (7%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE-RPG 489 YL+ + T EA I+DPV + ++ + +G+ + A G D+ K Sbjct: 16 YLVGCQRTGEAIIIDPVRDLSKYIEVADSEGLTITQATETHIHADFASGIRDVAKRLNAN 75 Query: 490 LIVYG-GDDRIG-----ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651 + V G G+D +G + T+ V+H ++GN+ ++ L TP HT I + +T G Sbjct: 76 IYVSGEGEDALGYKNMPSKTQFVKHGDIIQVGNVKLEVLHTPGHTPESISFLLT-DLGGG 134 Query: 652 DSV---VFTGDTLFLGGCGR 702 SV +F+GD +F+G GR Sbjct: 135 SSVPMGLFSGDFIFVGDIGR 154 >UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrolase; n=9; Rhodobacteraceae|Rep: Probable hydroxyacylglutathione hydrolase - Rhodobacter capsulatus (Rhodopseudomonas capsulata) Length = 256 Score = 54.8 bits (126), Expect = 2e-06 Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 2/147 (1%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 +++ +P L DNY +L D AT +VD E VLK + ++ L Sbjct: 3 LELTPIPCLTDNYAWLWHDTATDTVVVVDVPEAAPVLKVLTDRRWQLHHILITHHHADHI 62 Query: 454 GGNEDLIKERPGLIVYGGDD--RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF 627 G E L + + D R+ L V +G Q + HT GHI ++ Sbjct: 63 AGVEALAQATGAKVAGAAADAHRLPPLDHPVAPGDVLHLGMEAAQVIAADGHTLGHIAWY 122 Query: 628 VTAPEEGNDSVVFTGDTLFLGGCGRFF 708 + P G ++F+GD+L GCGR F Sbjct: 123 L--PGAG---LLFSGDSLMSWGCGRLF 144 >UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira|Rep: Zn-dependent hydrolase - Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) Length = 269 Score = 54.0 bits (124), Expect = 4e-06 Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 4/135 (2%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 N+ Y++ + T E +DP + + + K ++ +G L GN L+ +R Sbjct: 14 NFTYILRNSETSETLSIDPYDSEQIEKFLDSKGWTLDFLLNTHEHEDHTSGNTGLV-QRY 72 Query: 487 GLIVYGGDDRIGALTKKVEHNTK----FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND 654 G VY + IG + K + ++ L TP HT H+C + E Sbjct: 73 GCTVYSHPEGIGKIPHATHPLKKGDFLLRSSKEYLEILDTPGHTFCHVCLLLV--ENQKP 130 Query: 655 SVVFTGDTLFLGGCG 699 +FTGDT+F G G Sbjct: 131 KAIFTGDTIFNAGVG 145 >UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter sp. BAL39|Rep: Rhodanese-like protein - Pedobacter sp. BAL39 Length = 459 Score = 54.0 bits (124), Expect = 4e-06 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 1/133 (0%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 +Y Y I+ + K+ ++DP P+ + G + + ++ Sbjct: 13 HYSYAILSNSEKKVILIDPARNPQPYYDFAAKHGATIVGVIETHPHADFVSSHLEIHMTT 72 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 I + + + +G L ++ + TP H+ IC + + GND V Sbjct: 73 SAKIYSHTLTGVSYPQTPFDEGAEIVLGELKLKSIHTPGHSPDSIC--IILEQNGNDKAV 130 Query: 664 FTGDTLFLGGCGR 702 FTGDTLF+G CGR Sbjct: 131 FTGDTLFIGDCGR 143 >UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2; Gammaproteobacteria|Rep: Hydroxyacylglutathione hydrolase - Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospirahalophila (strain DSM 244 / SL1)) Length = 255 Score = 54.0 bits (124), Expect = 4e-06 Identities = 44/142 (30%), Positives = 63/142 (44%), Gaps = 2/142 (1%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 L AL DNY+++ D + A VDP + V + + + L GG + Sbjct: 7 LAALADNYIWMARDASGTTAFAVDPGDAAVVEAWLHDHQLRLAAVLVTHHHGDHTGGVAE 66 Query: 469 LIKERPGLIVYG-GDDRIGALTKKVEHNTKFKI-GNLNVQCLFTPCHTTGHICYFVTAPE 642 L ER + V+G + I + + F + G + L P HT GHI Y Sbjct: 67 LA-ERHRVPVFGPATETIPTVDHPITGGEHFSLEGFGEFRVLDCPGHTAGHIAYLW---- 121 Query: 643 EGNDSVVFTGDTLFLGGCGRFF 708 EG+ +F+GD LF GGCGR F Sbjct: 122 EGH---LFSGDALFAGGCGRVF 140 >UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium cellulolyticum H10|Rep: Beta-lactamase-like - Clostridium cellulolyticum H10 Length = 235 Score = 54.0 bits (124), Expect = 4e-06 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 7/138 (5%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLK-AVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 N +Y+I+D T+ A+VDP ++K + + + ++K Sbjct: 29 NNVYIIIDSQTRHTAVVDPAWNIGLIKDTLNKLQAEVKVILLTHSHYDHTNLVNSMLKIY 88 Query: 484 PGLIVYGGDDRIGALTKK------VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 P VY + K V+ K+G +++C+ TP HT G +C+FV Sbjct: 89 PAK-VYMSKTEVDYYNYKCNSLVPVQDGEVIKLGYTDIKCILTPGHTMGGMCFFV----- 142 Query: 646 GNDSVVFTGDTLFLGGCG 699 D +FTGDT+F+ GCG Sbjct: 143 --DGSLFTGDTIFMEGCG 158 >UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; n=1; Bdellovibrio bacteriovorus|Rep: Hydroxyacylglutathione hydrolase GloB - Bdellovibrio bacteriovorus Length = 251 Score = 53.6 bits (123), Expect = 5e-06 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 2/149 (1%) Frame = +1 Query: 268 KNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXX 447 K V+++P DNY++++ D AT++A VDP + V+ + ++L Sbjct: 3 KKEHVELVPIFDDNYVFILTDDATQKAVAVDPGDAGPVIDFLRANKLDLAAILLTHHHSD 62 Query: 448 XAGGNEDL--IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHIC 621 GG +L + P +I + ++ G + + P HT GHI Sbjct: 63 HIGGVGELKAAFDCPVYAPQKNQKQIPVADQWLKEGDSVTCGPWDFTVMELPGHTLGHIA 122 Query: 622 YFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 Y+ +F+GD +F GCGR F Sbjct: 123 YW-----NQKHKWLFSGDVIFGLGCGRLF 146 >UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Beta-lactamase domain protein - Clostridium beijerinckii NCIMB 8052 Length = 224 Score = 53.6 bits (123), Expect = 5e-06 Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 7/139 (5%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 +N Y+I++ KEA I+DP + + ++ + GV+L E L+K Sbjct: 16 NNCTYIIINNDIKEAVIIDPAWDLEKIVANLNTNGVSLSSILLTHSHYDHTNLVEPLLKI 75 Query: 481 RPGLIVYGGDDRI---GALTKK---VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642 VY I G K V + K IG L + C+ TP HT G +C+ + Sbjct: 76 F-NCQVYMAKKEINYYGFRCKNLNPVNDSDKISIGKLKMDCVLTPGHTAGGMCFKL---- 130 Query: 643 EGNDSVVFTGDTLFLGGCG 699 ++ +FTGDT+F+ GCG Sbjct: 131 ---ENKLFTGDTIFIRGCG 146 >UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 524 Score = 53.6 bits (123), Expect = 5e-06 Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 1/125 (0%) Frame = +1 Query: 331 KATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG 507 ++ K A I+DP+ + + + ++G L + D+ K IV+G Sbjct: 31 ESDKVAVIIDPMRDYQRYIDLLNQRGATLKYVIETHFHADFVSSHLDIAKITGATIVFGP 90 Query: 508 DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL 687 K +IG++ +Q L TP HT CY + E VFTGDTLFL Sbjct: 91 TASPKYEIKVASDEEILEIGSVKLQVLHTPGHTPESSCYLLL-DENNTAQCVFTGDTLFL 149 Query: 688 GGCGR 702 G GR Sbjct: 150 GDVGR 154 >UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamily protein; n=11; Bacteria|Rep: Possible Beta-lactamase-like superfamily protein - Psychrobacter arcticum Length = 249 Score = 52.8 bits (121), Expect = 8e-06 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 2/137 (1%) Frame = +1 Query: 298 LQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL 471 L Y YL+ D+ T +A ++DPV L V G++L ++ Sbjct: 10 LSSTYTYLLGDEDTGQAILIDPVIATMDRDLAEVHRLGLDLVYTVDTHIHADHITAALEM 69 Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651 + I DR+ + +E T ++ + + L TP HT GH Y Sbjct: 70 KRAVGSKIAAPAFDRLPCVDVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLF------- 122 Query: 652 DSVVFTGDTLFLGGCGR 702 + VFTGD L + GCGR Sbjct: 123 NEQVFTGDALLIDGCGR 139 >UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2; cellular organisms|Rep: Hydroxyacylglutathione hydrolase - Syntrophus aciditrophicus (strain SB) Length = 485 Score = 52.8 bits (121), Expect = 8e-06 Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 Y YL+ D ++EA ++DP V L+A QG + G+ +L R Sbjct: 47 YSYLVGD--SREAVVIDPRRDIDVYLEAATFQGYRIVAVLETHRHEDFVLGSVELAA-RT 103 Query: 487 GLIVYGGDDRIG-ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 G ++ D + + V +KIG L ++ + +P HT G + Y + +GN +V Sbjct: 104 GAEIWHADGQWDYQYGEAVGDGQTWKIGRLKLEAIHSPGHTPGSMSYLLY-DADGNPWMV 162 Query: 664 FTGDTLFLGGCGR 702 FTGD LF G GR Sbjct: 163 FTGDALFAGDVGR 175 >UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2; sulfur-oxidizing symbionts|Rep: Beta-lactamase domain protein - Ruthia magnifica subsp. Calyptogena magnifica Length = 240 Score = 52.4 bits (120), Expect = 1e-05 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 5/139 (3%) Frame = +1 Query: 298 LQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474 L+D+ ++ I D TK AIVDP + ++ + +G L ++++ Sbjct: 22 LEDS-IHFIFDHNTKTCAIVDPAWDAPLFIQRIHNKGYILTDIWLTHWHFDHTNAVDEIV 80 Query: 475 KERPGLIVYGGDD----RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642 K I G ++ +I +L + V++N IGN + + TP H+ G ICY + Sbjct: 81 KATGAKITVGVNEVPYLQIDSLPETVDNNDTIFIGNTPAKIINTPGHSAGGICYLL---- 136 Query: 643 EGNDSVVFTGDTLFLGGCG 699 D + GDTLF+ G G Sbjct: 137 ---DGHIIAGDTLFVYGAG 152 >UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1; Methanoculleus marisnigri JR1|Rep: Beta-lactamase domain protein - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 467 Score = 52.4 bits (120), Expect = 1e-05 Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 2/122 (1%) Frame = +1 Query: 343 EAAIVDPVEPKTVLKAV-EEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519 EAA++DP + AV E +G+ + G+ +L + I++G + Sbjct: 23 EAAVIDPRRDCLIYAAVAEREGMKITKIFETHKNEDYVIGSRELARPTGAEILHGAREEF 82 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE-EGNDSVVFTGDTLFLGGC 696 G T E T F +G+L ++ L TP HT I + G+ +VFTGD LF G Sbjct: 83 GFGTGVHEGET-FTVGSLELEILETPGHTIESISLLLRDRSVSGDPLMVFTGDALFAGDV 141 Query: 697 GR 702 GR Sbjct: 142 GR 143 >UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5; Shewanella|Rep: Hydroxyacylglutathione hydrolase - Shewanella sp. (strain MR-4) Length = 295 Score = 52.0 bits (119), Expect = 1e-05 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 10/155 (6%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 + + + A DNY++++ + + +VDP + VL + + + L Sbjct: 30 LTITAINAFNDNYIWVLRQDSQQNVYVVDPGDANVVLDYLHKHQLTLAGILITHHHRDHT 89 Query: 454 GGNEDL---IKERPG--LIVYGGD-DRIGALTKKVEHNTKFKIG----NLNVQCLFTPCH 603 GG L +++ G L VYG + I + ++ + + V L P H Sbjct: 90 GGIAALAAHVEQTTGHTLAVYGPQSEAIQGINLPIDPKPSDTLTLPFIDAPVHILSVPGH 149 Query: 604 TTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 T GHI Y V D +F GDTLF GCGR F Sbjct: 150 TAGHIAYLV-------DGALFCGDTLFSAGCGRLF 177 >UniRef50_Q71KM2 Cluster: Glyoxalase II; n=8; Plasmodium|Rep: Glyoxalase II - Plasmodium falciparum Length = 322 Score = 51.6 bits (118), Expect = 2e-05 Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Frame = +1 Query: 286 ILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNE 465 I+P +DNY Y+ D +E +VDP + + +++ + + GN+ Sbjct: 62 IIPFYKDNYSYIFYDDK-EEGIVVDPADYNIINDISKKENIKIKHVLCTHKHSDHNNGNQ 120 Query: 466 DLIKERPGLIVYGGDDRIGA-LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642 ++ + VYG + + + + + T F+I N + + H+ + Y + Sbjct: 121 YYYEKN--INVYGIKEYDNKYINQDISNLTHFQINNFKINIFLSNFHSKNQVSYLIENDN 178 Query: 643 -EGNDSVVFTGDTLFLGGCGRFF 708 + ++ FTGD LF+ G G+ F Sbjct: 179 NKSKKNIFFTGDFLFISGIGKNF 201 >UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular organisms|Rep: Metallo-beta-lactamase - Methanosarcina acetivorans Length = 481 Score = 51.6 bits (118), Expect = 2e-05 Identities = 41/133 (30%), Positives = 62/133 (46%), Gaps = 4/133 (3%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y++ K K AI+DP + ++ + +G+ + G+ DL E G Sbjct: 16 YILAGK--KSCAIIDPQRDVEIYIREAKSRGLKITHILETHLHADFVSGHMDLA-ELTGA 72 Query: 493 IVYGGDDRIGALTKK--VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND-SVV 663 +Y + VE +T F+I ++ V+ L TP HT HI Y V+ G D + V Sbjct: 73 PIYAPEAAKCEFEHVGLVEGDT-FEIEDMTVKVLETPGHTPEHISYVVSDTSRGPDPTAV 131 Query: 664 FTGDTLFLGGCGR 702 F GDTLF+G GR Sbjct: 132 FCGDTLFVGDVGR 144 >UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; Bacteria|Rep: Hydroxyacylglutathione hydrolase - Dinoroseobacter shibae DFL 12 Length = 256 Score = 51.2 bits (117), Expect = 2e-05 Identities = 41/137 (29%), Positives = 60/137 (43%), Gaps = 3/137 (2%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 NY L+ D ++ A VD + + A+++ G L G + IK Sbjct: 15 NYGVLLHDPSSGATASVDAGDAAALRTALKKTGWTLSEIWITHHHADHTDGVAE-IKAET 73 Query: 487 GLIVYGGDDR---IGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657 G V G + I + + +F V+ + TP HT I +++ P EG Sbjct: 74 GCTVIGPKPQSAPIAGVDTRYGDGDRFDFSGHEVRVIHTPGHTIDMINFYL--PAEG--- 128 Query: 658 VVFTGDTLFLGGCGRFF 708 VVFTGDTLF+ GCGR F Sbjct: 129 VVFTGDTLFVMGCGRLF 145 >UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrolase; n=17; Pasteurellaceae|Rep: Probable hydroxyacylglutathione hydrolase - Haemophilus influenzae Length = 238 Score = 50.8 bits (116), Expect = 3e-05 Identities = 37/140 (26%), Positives = 56/140 (40%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 LPAL DNY++L + IVD E + +E+Q + G Sbjct: 5 LPALNDNYIWLY-QRENLPLIIVDLPETDKLFAWLEKQNATIEAVLLTHEHDDHTQGVSA 63 Query: 469 LIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 K P + +YG + ++ + K N + + T HT H+ + V Sbjct: 64 FKKRYPTVPIYGPQECEKKGATQIVNEGKILTANYQIDVIPTGGHTKQHVSFLV------ 117 Query: 649 NDSVVFTGDTLFLGGCGRFF 708 D+ +F GD LF GCGR F Sbjct: 118 -DNHLFCGDALFSAGCGRVF 136 >UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein - Protochlamydia amoebophila (strain UWE25) Length = 468 Score = 50.4 bits (115), Expect = 4e-05 Identities = 39/146 (26%), Positives = 64/146 (43%), Gaps = 9/146 (6%) Frame = +1 Query: 292 PALQDNYMYLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNED 468 P L N YL+ D+ TKE ++DP T ++ A E +++ G + Sbjct: 9 PGLAIN-TYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHADFISGARE 67 Query: 469 L---IKERPGLIV--YGGDDRIGALTKK-VEHNTKFKIGNLNVQCLFTPCHTTGHICYFV 630 L +K P + +GG+ + A V+ G++ ++ L TP HT HI + Sbjct: 68 LKFQLKNAPIIYSSGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWIC 127 Query: 631 TAPEEGNDS--VVFTGDTLFLGGCGR 702 +D +F+GD LF+G GR Sbjct: 128 YDETRSHDLPWFIFSGDCLFVGSVGR 153 >UniRef50_A6BZ99 Cluster: Putative uncharacterized protein; n=2; Bacteria|Rep: Putative uncharacterized protein - Planctomyces maris DSM 8797 Length = 487 Score = 50.4 bits (115), Expect = 4e-05 Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 14/143 (9%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YL+ + TKEA +VDP L+ +GV L G +L +R G Sbjct: 16 YLVGCQKTKEAVVVDPGRDIDQYLETARREGVKLTAVAETHIHADYVSGARELA-DRVGA 74 Query: 493 IVYGGDDRIGALTKKVEHNTKFK-----------IGNLNVQCLFTPCHTTGHICYFVTAP 639 +Y D+ G K E+ +++K IGN+ Q L TP HT I + +T Sbjct: 75 KLYVSDE--GPAEWKYEYASQYKSQLLKDGDTFLIGNIQFQVLHTPGHTPESISFLLTDQ 132 Query: 640 EEGNDSV--VFTGDTLFLGGCGR 702 G +FTGD +F+G GR Sbjct: 133 GGGASEPMGIFTGDFVFVGSIGR 155 >UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; Bacillus|Rep: Hydroxyacylglutathione hydrolase - Bacillus amyloliquefaciens Length = 230 Score = 50.0 bits (114), Expect = 6e-05 Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 7/155 (4%) Frame = +1 Query: 256 DHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXX 432 DH Y+ +K + NY Y+I D++ K A VDP E + + E V+L Sbjct: 7 DHTYEVHQIKTYHQMWSNYCYIIADRSKKSAIAVDPSWEIDKITDKLHELDVDLSAILLT 66 Query: 433 XXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKK------VEHNTKFKIGNLNVQCLFT 594 E L ++ +Y I + +E F G ++ + T Sbjct: 67 HSHYDHVNLAEPL-QQIYHSDIYMSSAEIDFYQFRCRNLIALEDGQTFAAGGFIIRSILT 125 Query: 595 PCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 P HT G +CY ++ +FTGDT+F GCG Sbjct: 126 PGHTAGGMCYLLS-------DHLFTGDTVFTEGCG 153 >UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily protein; n=17; Bacteroidetes|Rep: Metallo-beta-lactamase superfamily protein - Flavobacteriales bacterium HTCC2170 Length = 492 Score = 50.0 bits (114), Expect = 6e-05 Identities = 42/164 (25%), Positives = 68/164 (41%), Gaps = 2/164 (1%) Frame = +1 Query: 217 LIRNQREAHSSQEDHQYKNMDVK-ILPALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKA 390 L NQ E + + + + + M ++ I + Y I K EAAI DP+ E + + Sbjct: 3 LYGNQNEHNFTVKFYSHFTMRIEQIYTGCLAHAAYYIESKG--EAAIFDPLREVQPYIDR 60 Query: 391 VEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGN 570 + + G+ DL K+ IV+G E N F++G+ Sbjct: 61 ANKDNAKVKYVFETHFHADFVSGHLDLKKKTGAQIVFGPTANPNYDALIAEDNQIFELGD 120 Query: 571 LNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 ++ L TP HT Y + + ++ TGDTLF+G GR Sbjct: 121 YKIKVLHTPGHTMESTTYLLIDENDKQHGII-TGDTLFIGDVGR 163 >UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 321 Score = 50.0 bits (114), Expect = 6e-05 Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 21/80 (26%) Frame = +1 Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYF-------VTAPEEGN------------- 651 K+ ++ T + G + L+ PCHTTGH+ Y ++ E N Sbjct: 124 KETKNETSIE-GEFQIDFLYVPCHTTGHVLYHFKPHNKTISTEESVNFERQEVTGYNLYS 182 Query: 652 -DSVVFTGDTLFLGGCGRFF 708 D +FTGDTLF+GGCGRFF Sbjct: 183 VDECLFTGDTLFIGGCGRFF 202 >UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; Encephalitozoon cuniculi|Rep: HYDROXYACYL GLUTATHION HYDROLASE - Encephalitozoon cuniculi Length = 263 Score = 49.6 bits (113), Expect = 8e-05 Identities = 20/52 (38%), Positives = 30/52 (57%) Frame = +1 Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGRFF 708 KF+ ++ ++C TPCHT C++V + + TGDTL GCG+FF Sbjct: 124 KFRFKDVEIECFHTPCHTVDSFCFYV------GEKYLATGDTLLFLGCGKFF 169 >UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: Hydroxyacylglutathione hydrolase - marine gamma proteobacterium HTCC2143 Length = 258 Score = 49.2 bits (112), Expect = 1e-04 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 N+ YLI + A ++DP + V + + + ++L GN +L+ E Sbjct: 14 NFTYLI-ELEDGSALVIDPWDAGEVNRLLHQWQLSLRAIINTHEHWDHIQGNPELVAEHS 72 Query: 487 GLIVY--GGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGNDS 657 + G ++ L++ + + + ++ L TP HT H+C+ V E+G + Sbjct: 73 CEVWAHSNGQGKVPGLSRMLTAGELIDLDTGVQLRVLDTPGHTYAHLCFLVL--EQGIEV 130 Query: 658 VVFTGDTLFLGGCG 699 VFTGDTLF G G Sbjct: 131 AVFTGDTLFNAGVG 144 >UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosarcina|Rep: Metallo-beta-lactamase - Methanosarcina acetivorans Length = 457 Score = 48.8 bits (111), Expect = 1e-04 Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Frame = +1 Query: 343 EAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG--DD 513 EA ++DP V +G+ + G+ +L K I +G D Sbjct: 23 EAIVIDPRRDCQVYFDLARSKGMKIKYIFETHRNEDYIIGSLELEKLTDAGIYHGSGVDF 82 Query: 514 RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTGDTLFLG 690 + G + KK +F G L + L TP HT + Y +T P+ G + + VFTGD LF+G Sbjct: 83 KYGNILKK--DRQEFIFGALKLTALHTPGHTDESMSYVLTDPDAGKEPIMVFTGDALFVG 140 Query: 691 GCGR 702 GR Sbjct: 141 DVGR 144 >UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2; Chloroflexus|Rep: Beta-lactamase-like:Rhodanese-like - Chloroflexus aurantiacus J-10-fl Length = 466 Score = 48.4 bits (110), Expect = 2e-04 Identities = 40/140 (28%), Positives = 62/140 (44%), Gaps = 11/140 (7%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YLI T EA ++DP+ + + L+ ++G+ + G +L R G Sbjct: 16 YLIGCAKTGEAMVIDPMRDVEPYLRVAAKEGLRITHVTETHIHADFVSGVRELAA-RTGA 74 Query: 493 IVY---GGDDRIGALTKKVEHNTKFK------IGNLNVQCLFTPCHTTGHICYFVTAPEE 645 +Y GD ++E K +GN+ VQ + TP HT HI + +T Sbjct: 75 QMYLSDMGDANWKYAYPEIEKAILVKDGDTWMVGNIKVQVIATPGHTPEHIAFMITDTAG 134 Query: 646 GNDSV-VFTGDTLFLGGCGR 702 + + VFTGD LF+G GR Sbjct: 135 ADQPMGVFTGDFLFVGDVGR 154 >UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 498 Score = 48.4 bits (110), Expect = 2e-04 Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 1/120 (0%) Frame = +1 Query: 331 KATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGG 507 ++ K+A ++DP+ + ++ +++ + GG+ D+ K+ IV G Sbjct: 49 ESEKQAILIDPLRDIQQYIEYSQKREAKITHVFLTDFHSDFIGGHVDIQKQADAQIVLGP 108 Query: 508 DDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL 687 + + N IG + +Q L+TP HT C+ + ++ +FTGDTL+L Sbjct: 109 TSIADFEFHQAKDNEIISIGKIKMQVLYTPGHTNESTCFLLL--DDERQHAIFTGDTLYL 166 >UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Beta-lactamase-like - Herpetosiphon aurantiacus ATCC 23779 Length = 464 Score = 48.0 bits (109), Expect = 2e-04 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 12/141 (8%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YL+ + T EA ++DP V L A + G+ + G+ +L + G Sbjct: 16 YLVGCQKTGEALVIDPHRDSAVYLNAAQAAGLRISAITETHIHADFVSGSRELA-QITGA 74 Query: 493 IVYGGDDRIGAL----------TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642 +Y A + + + +GNL ++ L TP HT H+ + +T Sbjct: 75 KLYLSAAGTAAWQYAFASSNPNVQLINDGDSWMVGNLKIEVLHTPGHTPEHVIFMLTDTP 134 Query: 643 EGNDSV-VFTGDTLFLGGCGR 702 G++ + +FTGD LF G GR Sbjct: 135 AGDEPMGIFTGDLLFAGDVGR 155 >UniRef50_Q1AVJ8 Cluster: Beta-lactamase-like protein; n=4; Bacteria|Rep: Beta-lactamase-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 479 Score = 47.6 bits (108), Expect = 3e-04 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 7/136 (5%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y I +AT EA +VDP L+ + G+ + G+ +L G Sbjct: 16 YFIGCQATGEAVVVDPRRDIGAYLEMARKNGMRIAAVTETHIHADYLSGSRELAAAT-GA 74 Query: 493 IVYGGDD-----RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND- 654 +Y D+ + G +++ + ++GN+ ++ L TP HT H+ + VT + Sbjct: 75 TLYLSDEGDEPWKYGFEGERLHDGDEIRVGNVVLKALHTPGHTPEHLSFLVTDGAAAEEP 134 Query: 655 SVVFTGDTLFLGGCGR 702 + TGD +F+G GR Sbjct: 135 GYILTGDFVFVGDLGR 150 >UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=11; Proteobacteria|Rep: Metallo-beta-lactamase superfamily - Nitrosomonas europaea Length = 262 Score = 46.8 bits (106), Expect = 5e-04 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 4/142 (2%) Frame = +1 Query: 295 ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474 A +DNY++++ ++ + A I+DP + VL + +Q + GG L+ Sbjct: 9 AFRDNYIWIVHNQ--QFALIIDPGDATPVLTWLRQQKLQPIAILCTHHHHDHTGGIS-LL 65 Query: 475 KERPGLIVYG-GDDRIGALTKKV-EHNTK-FKIGNLNVQCLFTPCHTTGHI-CYFVTAPE 642 ++ + VYG ++I +T + E +T F +L + L P HT GHI C+ Sbjct: 66 VQKFEIPVYGPASEKIPGMTHPLAEGDTLVFPELSLELSILDVPGHTAGHIACH------ 119 Query: 643 EGNDSVVFTGDTLFLGGCGRFF 708 + +F GDTLF GCGR F Sbjct: 120 --GQNRLFCGDTLFACGCGRIF 139 >UniRef50_Q41EG0 Cluster: Beta-lactamase-like:Rhodanese-like; n=4; Bacteria|Rep: Beta-lactamase-like:Rhodanese-like - Exiguobacterium sibiricum 255-15 Length = 468 Score = 46.8 bits (106), Expect = 5e-04 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 10/139 (7%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y++ + T EA ++DP + LK ++G+++ G + ER Sbjct: 16 YMVGCQMTGEAIVIDPSRDIEGYLKEAAKEGLHIVATAETHIHADFVSGTREFA-ERFDT 74 Query: 493 IVYGGDD---------RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 Y D+ K V +FK+GN+ + + TP HT H+ + + ++ Sbjct: 75 TAYLSDEGDADWKYEFAADIDAKLVTDGNRFKVGNVTFEVMHTPGHTPEHVSFLLYDRDQ 134 Query: 646 GNDSVVFTGDTLFLGGCGR 702 +FTGD +F+G GR Sbjct: 135 TVPMGIFTGDFVFVGDIGR 153 >UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus|Rep: Beta-lactamase-like - Synechococcus sp. RS9917 Length = 370 Score = 46.8 bits (106), Expect = 5e-04 Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 2/142 (1%) Frame = +1 Query: 283 KILPALQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 ++ A + YL+VD + + ++DPV + L V E GV+L Sbjct: 20 QLFDAETGTFSYLLVDVPSAKGVLIDPVFERHERDLALVRELGVDLVACLDTHAHADHVT 79 Query: 457 GNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636 G+ + + I R +T+ ++H + G ++ TP HT G + + + Sbjct: 80 GSWLMHEATGAAIGLAAAARAENVTQPLQHGDRVGFGARALEVRATPGHTDGCLTFVLD- 138 Query: 637 PEEGNDSVVFTGDTLFLGGCGR 702 + S FTGD L + GCGR Sbjct: 139 ----DASAAFTGDALLIRGCGR 156 >UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acinetobacter baumannii ATCC 17978|Rep: Beta-lactamase-like protein - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 231 Score = 46.4 bits (105), Expect = 7e-04 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 3/134 (2%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y Y++ + T+ A ++DPV + + K +E+ L DL++ER Sbjct: 14 YTYMLGCEETRGAVLIDPVASDIEIYAKELEQHQFTLIYTLDTHVHADHITA-ADLLRER 72 Query: 484 PGL-IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 V + + + K+GNL+++ +TP HT Y V GN + Sbjct: 73 FHCKSVLHRNSEVSCGDILITDGCMLKVGNLSIEARYTPGHTNACTSYLV-----GN--M 125 Query: 661 VFTGDTLFLGGCGR 702 +FTGD L + GCGR Sbjct: 126 IFTGDALLIDGCGR 139 >UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Halobacteriaceae|Rep: Beta-lactamase domain protein - Halorubrum lacusprofundi ATCC 49239 Length = 402 Score = 46.4 bits (105), Expect = 7e-04 Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 6/135 (4%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKT--VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER-P 486 YL+ D EAAIVDP+ T L EE GV L G +L E Sbjct: 150 YLLYDGG--EAAIVDPLRAFTDRYLADAEELGVELTYAFDTHVHADHISGLRNLADEGVE 207 Query: 487 GLIVYGGDDRIGALTKKV---EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657 ++ DR V E +F +G+ V+ +FTP HTTG Y + DS Sbjct: 208 AMLPAAAADRGVTYADDVTLVEDGDEFTVGDATVETVFTPGHTTGMTSYLL------GDS 261 Query: 658 VVFTGDTLFLGGCGR 702 ++ TGD LF+ R Sbjct: 262 LLATGDGLFIESVAR 276 >UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Actinomycetales|Rep: Beta-lactamase domain protein - Mycobacterium sp. (strain KMS) Length = 238 Score = 46.0 bits (104), Expect = 0.001 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 19/151 (12%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPK-TVLKAVEEQGVNLXXXXXXXXXXXXAGGNE---DL- 471 N+ YLI D+ T + +VDP ++ A+E G++L GG+ +L Sbjct: 30 NFAYLIGDRETGDCVVVDPAYAAGDLVDALEADGMHLSGVLATHHHPDHVGGSMMGFELK 89 Query: 472 ----IKERPGLIVYGGD------DRIGALTKKV----EHNTKFKIGNLNVQCLFTPCHTT 609 + ER + V+ R+ + + +H +G ++++ L TP HT Sbjct: 90 GLAELLERVSVPVHVNSHEADWVSRVTGIARSELTAHDHGDVVSVGGIDIELLHTPGHTP 149 Query: 610 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 G C+ + D + GDTLFL GCGR Sbjct: 150 GSQCFLL-------DGRLVAGDTLFLEGCGR 173 >UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_61, whole genome shotgun sequence - Paramecium tetraurelia Length = 483 Score = 46.0 bits (104), Expect = 0.001 Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 1/160 (0%) Frame = +1 Query: 226 NQREAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKEAAIVDPVEP-KTVLKAVEEQ 402 N ++A S E+ + V L + Y I ++ EAAI+DP+ + +K E + Sbjct: 12 NTQKAQQSGENFFIQQFQVSCL----GQFSYYI--ESNNEAAIIDPMRDYEDYIKFSESR 65 Query: 403 GVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQ 582 + G+ DL K IV G K + +G ++ Sbjct: 66 NSVIKYVILTHLHADFVAGHLDLAKITGAQIVLGPQAVTQYQAKIAQDEELLPLGRAYLR 125 Query: 583 CLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 + TP HT C+ + ++ D VVF+GD+LFL GR Sbjct: 126 VVHTPGHTLESSCFVLVVDDK--DHVVFSGDSLFLEEVGR 163 >UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Predicted Zn-dependent hydrolase - Methanosphaera stadtmanae (strain DSM 3091) Length = 225 Score = 46.0 bits (104), Expect = 0.001 Identities = 19/52 (36%), Positives = 33/52 (63%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGG 693 +E+N ++GN ++ L+TP HT+G +CY+ E ++FTGDT++ G Sbjct: 119 LENNNVIEVGNWTLKVLYTPGHTSGSVCYY-----EEEKRILFTGDTVYAKG 165 >UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteobacteria|Rep: Beta-lactamase-like - delta proteobacterium MLMS-1 Length = 213 Score = 45.2 bits (102), Expect = 0.002 Identities = 23/47 (48%), Positives = 30/47 (63%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +G + +Q + TP HT G IC + TAP +FTGDTLF+GG GR Sbjct: 118 LGTIELQVIHTPGHTPGGICLY-TAPH------LFTGDTLFVGGVGR 157 >UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 209 Score = 45.2 bits (102), Expect = 0.002 Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 11/140 (7%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y+ D ATK AIVDP + +L AV G+ + G +L K P + Sbjct: 24 YIFGDDATKMGAIVDPGGDAAGILAAVRGLGLTVSAIFLTHGHYDHVGALPELRKALPDV 83 Query: 493 IVYGGDD----RIGAL------TKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPE 642 VY R G+L T + +G L V+ + P HT G +C V Sbjct: 84 PVYLHPAEKAVRDGSLIPDPGPTVDYGDGSTVAVGGLTVEVIHAPGHTPGGVCLKV---- 139 Query: 643 EGNDSVVFTGDTLFLGGCGR 702 +FTGDTLF G GR Sbjct: 140 ---GDTLFTGDTLFRGSMGR 156 >UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Dichelobacter nodosus VCS1703A|Rep: Metallo-beta-lactamase superfamily protein - Dichelobacter nodosus (strain VCS1703A) Length = 235 Score = 45.2 bits (102), Expect = 0.002 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 5/138 (3%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAV-EEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 DN+MY+I + EA +VDP ++K V ++ + L DL + Sbjct: 14 DNFMYIIANGG--EAVVVDPAWNAELVKTVLAQEYLTLTAILLTHAHDDHTNAVSDLYSD 71 Query: 481 RPGLIVYGGDDRIGALTKK----VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 L + + + A ++ + G +Q + TP HT G C++V Sbjct: 72 DVSLFLSADEYPLWANCPVDAVLLQDGDEIFCGADVIQMIATPGHTAGSCCFYV------ 125 Query: 649 NDSVVFTGDTLFLGGCGR 702 D+ + TGDTLF+ GCGR Sbjct: 126 -DNNLITGDTLFVYGCGR 142 >UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein; n=2; Geobacillus|Rep: Metallo-beta-lactamase family protein - Geobacillus thermodenitrificans (strain NG80-2) Length = 378 Score = 45.2 bits (102), Expect = 0.002 Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 4/124 (3%) Frame = +1 Query: 343 EAAIVDPVEPKTVLKAVEEQ-GVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVY--GGDD 513 EA +VDP+ V + V +Q GV + G + L ER G Y + Sbjct: 140 EALVVDPLRFIDVYEQVAQQEGVTITHIVDSHLHADHLSGGKALA-ERTGAAYYLMKSEG 198 Query: 514 RIGALTKKVEHNT-KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLG 690 + +H T F+ +L V + TP HT G + +FV N +F+GDT+F+G Sbjct: 199 AVFDFEPLEQHETIDFENVHLEVLAVKTPGHTPGSVSFFV------NGKWLFSGDTIFVG 252 Query: 691 GCGR 702 G GR Sbjct: 253 GLGR 256 >UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-PA - Drosophila melanogaster (Fruit fly) Length = 279 Score = 45.2 bits (102), Expect = 0.002 Identities = 37/133 (27%), Positives = 53/133 (39%), Gaps = 2/133 (1%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y YL+ D +A I+DPV + K + V++ G L G+ L K Sbjct: 61 YSYLLADLKNGQAVIIDPVLEQAKRDAQLVKDLGFELKYAINTHMHADHITGSGWLRKLT 120 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 V A + + + G + L TP HT G + Y + + V Sbjct: 121 GCQSVIAAASGAKA-DRHLNEGDRIDFGTHVIDALATPGHTNGCMTYVIK-----DQGCV 174 Query: 664 FTGDTLFLGGCGR 702 FTGDTL + GCGR Sbjct: 175 FTGDTLLIRGCGR 187 >UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1; Planctomyces maris DSM 8797|Rep: Putative uncharacterized protein - Planctomyces maris DSM 8797 Length = 471 Score = 44.8 bits (101), Expect = 0.002 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 9/138 (6%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL---IKER 483 YLI D+ T EA ++DP + + E +++ G+ +L + ++ Sbjct: 16 YLIGDEKTGEAVVIDPTRDVDDFIDYAREHDLHIRHIIETHIHADFVCGSRELKTRLDDQ 75 Query: 484 PGLIV--YGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH--ICYFVTAPEEG 648 P + YGG D ++V+ + ++G+L ++ P HT H + F + E Sbjct: 76 PLIYCSSYGGADWNQSFADRQVKESDSIQMGDLKLEFRHVPGHTPEHLAVLLFDQSRSET 135 Query: 649 NDSVVFTGDTLFLGGCGR 702 + +FTGD LF+G GR Sbjct: 136 SPWCMFTGDFLFVGDVGR 153 >UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 214 Score = 44.8 bits (101), Expect = 0.002 Identities = 40/151 (26%), Positives = 64/151 (42%), Gaps = 20/151 (13%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIK--- 477 + YL+ D+ + E ++DP + +++ ++E+GV L GN +I Sbjct: 14 FCYLVYDEVSGEGILIDPAGDEDGLIQLLKEKGVKLRYVVNTHGHPDHTCGNGKIIDATG 73 Query: 478 -------------ERP---GLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTT 609 +RP G G +VE + GNL ++ + TP HT Sbjct: 74 AKVVMHTLDDQYFQRPESKGFARMMGFQPAPPADVRVEDGDELTFGNLTMKFINTPGHTP 133 Query: 610 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 G C + +GN +FTGDTLF+G GR Sbjct: 134 GSCCVLI----DGN---LFTGDTLFVGAVGR 157 >UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bacteria|Rep: Beta-lactamase-like precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 251 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/56 (41%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-VVFTGDTLFLGGCGR 702 V+ + + GN+ V L TP HT IC V G++ V TGDTLF+G GR Sbjct: 93 VKDGQRLEAGNVVVDILHTPGHTPDSICLLVRDLRRGDEPWFVITGDTLFVGAAGR 148 >UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Metallo-beta-lactamase family protein - Plesiocystis pacifica SIR-1 Length = 234 Score = 44.4 bits (100), Expect = 0.003 Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 8/141 (5%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 DN++Y + DK T+ A+VDP ++L E V + E L+K Sbjct: 17 DNFIYFLGDKRTRSVAVVDPAWHAPSILAEAERLDVTISAILCTHSHFDHVDKVEALLKH 76 Query: 481 RPGLI------VYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAP 639 + + D + L +T ++G L + + TP HT G Y + Sbjct: 77 VDVPVHMLRPEIEFADFKCENLIASSPGDT-VRVGEQLEITMMHTPGHTPGSCSYRL--- 132 Query: 640 EEGNDSVVFTGDTLFLGGCGR 702 DS+V TGDTLF+ GCGR Sbjct: 133 ---RDSIV-TGDTLFVNGCGR 149 >UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like protein - Lentisphaera araneosa HTCC2155 Length = 213 Score = 44.4 bits (100), Expect = 0.003 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 20/142 (14%) Frame = +1 Query: 337 TKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDD 513 +KEA ++DP E +T+LK + QG+ + G ++ + + DD Sbjct: 25 SKEAILIDPGSEAETILKKINYQGLKIKAIIHTHAHLDHFGATHEVSESTDASVHLHKDD 84 Query: 514 ----RIGALTKK---------------VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636 I L + +E + F+ G ++ + TP H+ G C+ + Sbjct: 85 MPLWNIADLQAEMLGLPKCPHANVDHFIEDSQSFEFGEFKLEAIHTPGHSAGSTCFKI-- 142 Query: 637 PEEGNDSVVFTGDTLFLGGCGR 702 E ++ ++F+GDTLF G GR Sbjct: 143 -ENSDEQLLFSGDTLFRRGVGR 163 >UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2; Chloroflexus|Rep: Beta-lactamase-like - Chloroflexus aggregans DSM 9485 Length = 395 Score = 44.4 bits (100), Expect = 0.003 Identities = 20/50 (40%), Positives = 29/50 (58%) Frame = +1 Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 + +G+L ++ + P HT GH+ Y V AP + + TGD L L GCGR Sbjct: 228 RLPLGHLLIEAHWFPGHTPGHLVYRVIAP--NGERYLLTGDALLLSGCGR 275 >UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase related; n=4; Thermococcaceae|Rep: Hydroxyacylglutathione hydrolase related - Pyrococcus abyssi Length = 222 Score = 44.4 bits (100), Expect = 0.003 Identities = 22/56 (39%), Positives = 34/56 (60%) Frame = +1 Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 K+E + K+G + ++ + TP HT G C + EE + ++FTGDT+FLG GR Sbjct: 123 KLEDGDEIKVGKVKLRLIHTPGHTRGSSCLYY---EE--ERIMFTGDTVFLGTYGR 173 >UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate sulfurtransferase/ hydrolase (Probable hydroxyacylglutathione hydrolase) 2; n=1; Natronomonas pharaonis DSM 2160|Rep: Homolog 4 to thiosulfate sulfurtransferase/ hydrolase (Probable hydroxyacylglutathione hydrolase) 2 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 388 Score = 44.4 bits (100), Expect = 0.003 Identities = 34/133 (25%), Positives = 55/133 (41%), Gaps = 4/133 (3%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVE-PKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YL+ D AA VDP + A E+G + G L E Sbjct: 139 YLVADPEAGVAAAVDPTRHTDEFVAAAAERGWQIERVLDTHIHADHISGGRQLADELSVP 198 Query: 493 IVYG---GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 G D +G + + N +G+++++ +FTP HT+G Y V +++ + Sbjct: 199 YHLGERVSDRDVGVDYEPLARNEVVTVGDVDLKAVFTPGHTSGMASYLV------DENAL 252 Query: 664 FTGDTLFLGGCGR 702 TGDT+F+ GR Sbjct: 253 LTGDTVFVDSVGR 265 >UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrolase; n=2; Candidatus Blochmannia|Rep: Probable hydroxyacylglutathione hydrolase - Blochmannia floridanus Length = 256 Score = 44.0 bits (99), Expect = 0.004 Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 2/137 (1%) Frame = +1 Query: 295 ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474 +LQ NY+++I + ++ I+DP E V+K + + G LI Sbjct: 8 SLQTNYIWIIYNHI-RQCIIIDPGESLKVIKMLNHLQLIPEAILLTHNHRDHTNGVFTLI 66 Query: 475 KERPGLIVYGGDDRIGA--LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 + P + +YG + T V +I N ++ L P HT HI ++ Sbjct: 67 QHFPKIKIYGPIETQNQNFATITVSEGDTLQILNQEIKVLNFPGHTPHHIGFYYK----- 121 Query: 649 NDSVVFTGDTLFLGGCG 699 S +F+GDT+F GCG Sbjct: 122 --SWLFSGDTIFSAGCG 136 >UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica)|Rep: Beta-lactamase domain protein - Ruthia magnifica subsp. Calyptogena magnifica Length = 236 Score = 44.0 bits (99), Expect = 0.004 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 3/138 (2%) Frame = +1 Query: 298 LQDNYMYLIVDKATKEAAIVDPVEP--KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL 471 + Y YL+ D T +A I+D V+ + + +EE + L + L Sbjct: 12 ISSTYTYLLADMQTFDAIIIDAVDETKQRDIDLIEELNLKLKYILETHVHADHITSSCSL 71 Query: 472 IKE-RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEG 648 + IV G + I + N G+ + + TP HT G + Y V Sbjct: 72 KQHFMQAKIVLGSANIITCADILLNDNDTLSFGDYTLSAMATPGHTDGCMSYVV------ 125 Query: 649 NDSVVFTGDTLFLGGCGR 702 ++ +FTGDTL + CGR Sbjct: 126 -NNQIFTGDTLLIRSCGR 142 >UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like domain protein; n=7; Bacteria|Rep: Metallo-beta-lactamase/rhodanese-like domain protein - Gramella forsetii (strain KT0803) Length = 476 Score = 44.0 bits (99), Expect = 0.004 Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 5/134 (3%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG- 489 Y I D++ AAI+DP + L+ + GV G L G Sbjct: 24 YFICDESAGGAAIIDPRPDADIYLQKARQYGVTFTHVFETHIHADFMSGARQLKARCKGS 83 Query: 490 ---LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 + GD + V +F+ G + + TP HT H+ Y + + + Sbjct: 84 AKIFVSIEGDATYDFAYEPVREGDEFEFGQVKMMAKHTPGHTPEHLSYLLYESHKEDPWG 143 Query: 661 VFTGDTLFLGGCGR 702 + TGD+LF+ GR Sbjct: 144 IVTGDSLFVDSLGR 157 >UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|Rep: Bll1007 protein - Bradyrhizobium japonicum Length = 345 Score = 43.6 bits (98), Expect = 0.005 Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 2/142 (1%) Frame = +1 Query: 283 KILPALQDNYMYLIVDKATKEAAIVDPVEPKT--VLKAVEEQGVNLXXXXXXXXXXXXAG 456 ++ ++ Y Y++ + EA I+DPV K + + E + L Sbjct: 5 QLFDSVSGTYSYVLASRHGGEALILDPVLEKVDRYCQLLRELDLKLVKAVDTHLHADHVT 64 Query: 457 GNEDLIKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA 636 G +L + V G + + +V K I L++ ++TP HT Y + Sbjct: 65 GLGELRDRTHCMTVMGDQTKADVVAMRVADGDKVTIEGLSLDVMYTPGHTDDSYSYLM-- 122 Query: 637 PEEGNDSVVFTGDTLFLGGCGR 702 VFTGDTL + G GR Sbjct: 123 -----GDRVFTGDTLLIRGTGR 139 >UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; n=17; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Burkholderia mallei (Pseudomonas mallei) Length = 246 Score = 43.6 bits (98), Expect = 0.005 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 2/131 (1%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YL+ +VD V EP T L+A + G+ + L Sbjct: 16 YLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAA 75 Query: 493 IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-VVFT 669 V + K VE + ++GN+ ++ L TP HT HI VT + + T Sbjct: 76 YVLSTKADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALT 135 Query: 670 GDTLFLGGCGR 702 G TL +G GR Sbjct: 136 GHTLMIGDLGR 146 >UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16; Proteobacteria|Rep: Beta-lactamase-like - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 356 Score = 43.6 bits (98), Expect = 0.005 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 3/134 (2%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y YL+ D+A++EA ++DPV + + ++E G+ L G L+K+R Sbjct: 14 YTYLLADRASREAVLIDPVFEQVRRDAALLDELGLRLVATVDTHVHADHVTG-AWLLKQR 72 Query: 484 PG-LIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 G I + + + G + TP HT+G C + +E S+ Sbjct: 73 TGSTIAISAASGAQGADRYLNDGDRCAFGARYLTVRATPGHTSG--CISLVLDDE---SM 127 Query: 661 VFTGDTLFLGGCGR 702 FTGD L + G GR Sbjct: 128 AFTGDCLLIRGTGR 141 >UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 461 Score = 43.6 bits (98), Expect = 0.005 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 4/133 (3%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y+I A K AA++DP E + L QG+ + GN + I R G Sbjct: 16 YVIGCPAAKVAAVIDPKREIQEYLDITRNQGMKITHVIETHIHADHISGNLE-ITARTGA 74 Query: 493 IVYGGDDRIGALTKK-VEHNTKFKIGNLNVQCLFTPCHTTGHICYFV--TAPEEGNDSVV 663 +Y + A K ++ ++G ++ L TP HT I V T+ E + Sbjct: 75 DIYFYEKAPVAFKHKTLKEGDTIELGTAILEVLHTPGHTPHSISLLVKDTSRSEEEPWFM 134 Query: 664 FTGDTLFLGGCGR 702 TGD LF+G GR Sbjct: 135 LTGDLLFVGDVGR 147 >UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase domain protein - Victivallis vadensis ATCC BAA-548 Length = 205 Score = 43.6 bits (98), Expect = 0.005 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 2/133 (1%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQG-VNLXXXXXXXXXXXXAGGNEDLIKE 480 N+ YL V A +A +VDP + + + +AVE G + + + Sbjct: 16 NFSYLAV-AANGDALLVDPTGDAEVICRAVEAAGSITPRYILLTHGHLDHTQAVGEALGF 74 Query: 481 RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 P +V + + T+ + G V+ +FTP HT +CY +DS Sbjct: 75 FPAEVVAHPNHPLAGRTR-LRDGQLLPFGETAVEAIFTPGHTRDSVCY-----RFADDSA 128 Query: 661 VFTGDTLFLGGCG 699 VFTGD LF+G G Sbjct: 129 VFTGDVLFVGCIG 141 >UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 226 Score = 43.2 bits (97), Expect = 0.007 Identities = 38/148 (25%), Positives = 59/148 (39%), Gaps = 8/148 (5%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAG 456 V++ L N+ +I TK AA+VDP E +L A E+G + Sbjct: 13 VQLEVGLLQNFCEVIGCPQTKRAALVDPAFEVDRLLAAASERGWTVDTILLTHTHDDHVA 72 Query: 457 GNEDLIKE-------RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH 615 G ++ E P + A V IG+ ++ ++ P HT G Sbjct: 73 GLDEAFSETGATLRCHPAEVEVASAFVDRAKIVPVADGEDVAIGDGRMRAVYAPGHTPGC 132 Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 +C++ PE + TGD LF+G CG Sbjct: 133 VCWY--GPEA---KALITGDVLFVGSCG 155 >UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20; Pasteurellaceae|Rep: Uncharacterized protein HI1663 - Haemophilus influenzae Length = 212 Score = 43.2 bits (97), Expect = 0.007 Identities = 47/168 (27%), Positives = 74/168 (44%), Gaps = 25/168 (14%) Frame = +1 Query: 274 MDVKILP--ALQDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXX 444 M+++I+P A Q N + D+ K AAI+DP E + +++ +EE +NL Sbjct: 1 MNIEIIPVTAFQQNCSLIWDDE--KNAAIIDPGGEAERLIQRIEELDLNLKVLLLTHGHL 58 Query: 445 XXAGGNEDLIKERPGLIVYGGDDRIGALTKKV-EHNTKFKIGNL---------------- 573 G L K+ G+ ++G +++ L + + E +F + N+ Sbjct: 59 DHVGAAMQL-KQHFGVEIWGSNEKDKFLFESLPEQAQRFGLPNIDAFLPDRWFNQEGEIL 117 Query: 574 -----NVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 N + L P HT GHI + E V FTGD LF GG GR Sbjct: 118 KLDGFNFEILHLPGHTPGHIGFI-----EHEKKVAFTGDVLFQGGIGR 160 >UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyoxylases; n=2; Thermoanaerobacter|Rep: Zn-dependent hydrolases, including glyoxylases - Thermoanaerobacter tengcongensis Length = 214 Score = 42.7 bits (96), Expect = 0.009 Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 20/150 (13%) Frame = +1 Query: 313 MYLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG 489 +Y++ D+ T+E I+DP E +K ++E G+ + GG E++ G Sbjct: 20 LYVVWDRDTREGIIIDPGEVYDEIKNYIKENGIKVKHILLTHGHFDHIGGVEEIRAFTGG 79 Query: 490 LIVYGGDDRIGALT----------KKV---------EHNTKFKIGNLNVQCLFTPCHTTG 612 + +D L KKV + GN V+ + TP HT G Sbjct: 80 KVAISEEDAPMLLDPSQNLSEMVFKKVICSPADIILKDKDVLGFGNYYVEVISTPGHTKG 139 Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +C+ + V FTGDTLF G GR Sbjct: 140 SVCFKI-------GDVYFTGDTLFRGSIGR 162 >UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis|Rep: GloB protein - Wigglesworthia glossinidia brevipalpis Length = 251 Score = 42.7 bits (96), Expect = 0.009 Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = +1 Query: 301 QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 +DNY++L+ + K IVDP E ++ +++ + G E L K Sbjct: 10 EDNYIWLLYNN-DKNCIIVDPGEFISIHNICKKKKLTPVAIFLTHHHHDHVDGVESL-KT 67 Query: 481 RPGLIVYGGDDRIG-ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS 657 VYG + I TK V+ + + N + P HT GH+ ++ + Sbjct: 68 YFNTPVYGPKETIKYGTTKIVKEGDEIFLLNKCFKVFELPGHTLGHVGFY-------SPP 120 Query: 658 VVFTGDTLFLGGCGRFF 708 F GDTLF GCGR F Sbjct: 121 WFFCGDTLFSAGCGRLF 137 >UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Beta-lactamase-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 214 Score = 42.7 bits (96), Expect = 0.009 Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 20/154 (12%) Frame = +1 Query: 301 QDNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGG------ 459 Q+N Y++ D+A+ A+VDP E + AVE+ G+ + G Sbjct: 12 QEN-CYILGDEASGSGALVDPGDEAVRIALAVEQTGLEIEKILLTHAHIDHVGAVASLVE 70 Query: 460 -----------NEDLIKERPGLIVYGG--DDRIGALTKKVEHNTKFKIGNLNVQCLFTPC 600 +E L+++ P + G ++ L +E + ++G L ++ L+TP Sbjct: 71 EYGCPVLAHRESEPLLEQLPTQALMMGLRFGKVPRLDGYIEDRERVEVGGLTLEALYTPG 130 Query: 601 HTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 H GH+ +++ ++ + +GD LF G GR Sbjct: 131 HAPGHLAFYLE-----SEGALLSGDALFAGSVGR 159 >UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2; Roseiflexus|Rep: Beta-lactamase domain protein - Roseiflexus sp. RS-1 Length = 489 Score = 42.7 bits (96), Expect = 0.009 Identities = 38/140 (27%), Positives = 57/140 (40%), Gaps = 11/140 (7%) Frame = +1 Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YLI + E AIVDP + P+ L A ++G+ + L L Sbjct: 16 YLIGCIQSGECAIVDPGLPPEEYLVAAADRGLRITAIIETHFHADYFSTGRALAALTGAL 75 Query: 493 IVYGGDDRI-----GALTK----KVEHNTKFKIGNLNVQCLFTPCHTTGHICY-FVTAPE 642 I D I GA +V + +IGN+ ++ + TP HT H+ Y + P Sbjct: 76 IYAPSRDDIENDITGASVHYPHTRVRDGDEIRIGNIIIRAIHTPGHTPEHMAYAVIDTPR 135 Query: 643 EGNDSVVFTGDTLFLGGCGR 702 +V TGD+LF+ R Sbjct: 136 ASEPWMVLTGDSLFINDVAR 155 >UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 229 Score = 42.7 bits (96), Expect = 0.009 Identities = 24/61 (39%), Positives = 34/61 (55%) Frame = +1 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 G T+ + ++G++ +Q + TP HT G I F A E+GN + F GDTLF G G Sbjct: 122 GEPTRLLAEGDTIELGDICLQVIETPGHTPGGIVLFA-ATEQGN--IAFVGDTLFPGSHG 178 Query: 700 R 702 R Sbjct: 179 R 179 >UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas sp. JS666|Rep: Beta-lactamase-like - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 346 Score = 42.3 bits (95), Expect = 0.011 Identities = 22/56 (39%), Positives = 29/56 (51%) Frame = +1 Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +V+ +G L +Q L+TP HT +C D VFTGDTL +GG GR Sbjct: 89 RVDDGEMIVLGKLRLQVLYTPGHTVDSMCLVA-------DDRVFTGDTLLIGGTGR 137 >UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein; n=8; Clostridium|Rep: Metallo-beta-lactamase family protein - Clostridium perfringens (strain SM101 / Type A) Length = 206 Score = 42.3 bits (95), Expect = 0.011 Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 16/159 (10%) Frame = +1 Query: 274 MDVKILPA-LQDNYMYLIVDKATKEAAIVDPVEPKTVLK-AVEEQGVNLXXXXXXXXXXX 447 M +K +P + Y+++D+ TK+ IVDP E + ++ +E Sbjct: 1 MLIKTIPVGMYQANCYVVIDEETKDCIIVDPGEEASRIENVIESLDAKPKMILLTHGHFD 60 Query: 448 XAGGNEDLIKER--PGLIVYGGDDRI-------GALTK-----KVEHNTKFKIGNLNVQC 585 G + L ++ P I +D I G L K K KF N ++C Sbjct: 61 HVGAVQKLAEKYKIPFYIDKKDEDMIERNVDVFGKLPKADGYLKDGDTLKFS-DNYEIKC 119 Query: 586 LFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 L TP HT G +C+ + D+ +FTGDTLF GR Sbjct: 120 LETPGHTPGGLCFLI-------DNCLFTGDTLFRESIGR 151 >UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1; Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain protein - Solibacter usitatus (strain Ellin6076) Length = 465 Score = 42.3 bits (95), Expect = 0.011 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 2/121 (1%) Frame = +1 Query: 346 AAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIG 522 AA+VDP + ++ + G+ + G+++L I G + Sbjct: 24 AAVVDPQRDVGIYIEDAVKHGLRIAHVVETHLHADFISGHQELATLTGADIYLGAEAGAA 83 Query: 523 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-VVFTGDTLFLGGCG 699 V + + GN ++ L TP HT I VT E D V TGDTLF+G G Sbjct: 84 FPHVPVRDGDELRFGNCVLRFLETPGHTLESISILVTDLERSPDPYAVLTGDTLFIGDVG 143 Query: 700 R 702 R Sbjct: 144 R 144 >UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep: Orf c06001 protein - Sulfolobus solfataricus Length = 247 Score = 42.3 bits (95), Expect = 0.011 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 4/61 (6%) Frame = +1 Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFV---TAPEEGNDS-VVFTGDTLFLGGCG 699 ++V++ + K GN+ ++ L TP HT I + E N+ + TGDTLF+GG G Sbjct: 92 ERVKNGEEIKAGNVKIKVLHTPGHTPDSISVLIYDRRRDESWNEPWAILTGDTLFVGGLG 151 Query: 700 R 702 R Sbjct: 152 R 152 >UniRef50_Q81Q95 Cluster: Metallo-beta-lactamase/rhodanese-like domain protein; n=12; Bacillaceae|Rep: Metallo-beta-lactamase/rhodanese-like domain protein - Bacillus anthracis Length = 484 Score = 41.9 bits (94), Expect = 0.015 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDS-----VVFTGDTLFLGGCGR 702 V T+FK+G++ + TP HT I + VT + N + +FTGD +F+G GR Sbjct: 99 VREGTEFKVGHIKFNVIHTPGHTPESISFLVTDTSQNNYTNDKPIGIFTGDFIFVGDIGR 158 >UniRef50_Q1AUZ4 Cluster: Beta-lactamase-like protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Beta-lactamase-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 457 Score = 41.9 bits (94), Expect = 0.015 Identities = 32/122 (26%), Positives = 49/122 (40%), Gaps = 2/122 (1%) Frame = +1 Query: 343 EAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519 EAA+VDP E + L+ EE G ++ G L + I D + Sbjct: 23 EAAVVDPKWEIEEYLRIAEENGFDIAHILETHNHADHVSGKGRLAEATGAKIHISKDAGV 82 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT-APEEGNDSVVFTGDTLFLGGC 696 + + ++G + + L TP H H+ + V G+ VV TGD LF+G Sbjct: 83 EYDHEPLSDGDVVEVGGVRLVALSTPGHRPEHMSFLVEDTSRSGSPWVVLTGDFLFVGDL 142 Query: 697 GR 702 R Sbjct: 143 AR 144 >UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cystobacterineae|Rep: Myofibrillogenesis regulator 1 - Stigmatella aurantiaca DW4/3-1 Length = 220 Score = 41.9 bits (94), Expect = 0.015 Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 10/143 (6%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 DN++YL+ E +VDP + + +A+ E G L G +L+ Sbjct: 17 DNFVYLVGAADAPEVLVVDPAWDVPAIERAMAEDGKRLVGAFVSHCHKDHINGLPELLS- 75 Query: 481 RPGLIVYGGDDRI---------GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVT 633 R + VY + + G + V +G L TP HT G C Sbjct: 76 RHDVPVYAQREEVAFSEDLRALGGALRPVGPGEALTVGPRTFLALHTPGHTPGSHCLLA- 134 Query: 634 APEEGNDSVVFTGDTLFLGGCGR 702 D++V +GDT+F+ GCGR Sbjct: 135 -----GDALV-SGDTVFINGCGR 151 >UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; Clostridiales|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 207 Score = 41.9 bits (94), Expect = 0.015 Identities = 21/66 (31%), Positives = 34/66 (51%) Frame = +1 Query: 505 GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684 G + + V+ +T+ + V+ + TP HT G CY++ G + V+F+GDTLF Sbjct: 99 GQSYVFTKAEYVKADTQIETAGFQVEIIPTPGHTEGGCCYYI-----GEEHVLFSGDTLF 153 Query: 685 LGGCGR 702 GR Sbjct: 154 HNSIGR 159 >UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to hydroxyacylglutathione hydrolase - Candidatus Kuenenia stuttgartiensis Length = 189 Score = 41.5 bits (93), Expect = 0.020 Identities = 30/129 (23%), Positives = 54/129 (41%), Gaps = 1/129 (0%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YL+ D T+ +DP ++A + E+ + L G ++ + P + Sbjct: 20 YLVADPETRVGVFIDPGGFSDEIEAFIRERQILLQYLFFTHGHWDHTEGMQEFSRRYP-V 78 Query: 493 IVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTG 672 Y G+ + + ++ + ++G L + L TP HT + Y++ VFTG Sbjct: 79 KSYAGEGEVHSANNILQGSEIIEVGALQFKALSTPGHTLHGMSYYIPGG-------VFTG 131 Query: 673 DTLFLGGCG 699 D LF G G Sbjct: 132 DALFCGSVG 140 >UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase domain protein - Alkaliphilus metalliredigens QYMF Length = 207 Score = 41.5 bits (93), Expect = 0.020 Identities = 20/55 (36%), Positives = 29/55 (52%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 + H +G L ++ + TP HT G IC V ++ V+FTGDT+F GR Sbjct: 110 LSHGDTISVGALQLEVIHTPGHTPGSICLAVK-----DEKVIFTGDTVFSDALGR 159 >UniRef50_A1U0H3 Cluster: Beta-lactamase domain protein; n=1; Marinobacter aquaeolei VT8|Rep: Beta-lactamase domain protein - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 186 Score = 41.5 bits (93), Expect = 0.020 Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 2/132 (1%) Frame = +1 Query: 298 LQDNYMYLIVDKATKEAAIVDPV--EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL 471 + Y YL+ + T A ++DPV + L V + G+ L +L Sbjct: 10 VSSTYTYLLGCEETGRAVLIDPVINSVERDLAEVSKLGLKLEYTLDTHIHADHITSAREL 69 Query: 472 IKERPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651 ++ I D + VE F++G L+ Q + TP HT GH Y + Sbjct: 70 KQKAGSKIAAPAMDCLPCTDVGVEEGRPFQVGRLSFQPIHTPGHTDGHFAYRL------- 122 Query: 652 DSVVFTGDTLFL 687 D +FT D L + Sbjct: 123 DDRIFTDDALLI 134 >UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor; n=36; cellular organisms|Rep: ETHE1 protein, mitochondrial precursor - Homo sapiens (Human) Length = 254 Score = 41.5 bits (93), Expect = 0.020 Identities = 32/133 (24%), Positives = 54/133 (40%), Gaps = 2/133 (1%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPVEPKTVLKA--VEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 + YL+ D+ ++EA ++DPV A ++E G+ L G+ L Sbjct: 36 FTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLL 95 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 PG +E + G ++ +P HT G + + + + S+ Sbjct: 96 PGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLN-----DHSMA 150 Query: 664 FTGDTLFLGGCGR 702 FTGD L + GCGR Sbjct: 151 FTGDALLIRGCGR 163 >UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2; Anaeromyxobacter|Rep: Hydroxyacylglutathione hydrolase - Anaeromyxobacter sp. Fw109-5 Length = 255 Score = 41.1 bits (92), Expect = 0.027 Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 2/135 (1%) Frame = +1 Query: 301 QDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKE 480 +DNY+YL+ + +++ +VDP + L + V +GG+ + ++ Sbjct: 10 RDNYVYLLAEG--EDSVLVDPGDAAVALALAADHAVRPRFVLHTHGHLDHSGGSAE-VRA 66 Query: 481 RPGLIVYG--GDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGND 654 G V G D A + V + +G L V P HT G + + Sbjct: 67 ALGAEVLGHAADAAWFAPDRDVAGHRTLALGALRVAVHEVPGHTPGSVLFAWRGK----- 121 Query: 655 SVVFTGDTLFLGGCG 699 + TGDTLF GGCG Sbjct: 122 --LLTGDTLFWGGCG 134 >UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep: Hydrolase - Parvularcula bermudensis HTCC2503 Length = 451 Score = 41.1 bits (92), Expect = 0.027 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 5/128 (3%) Frame = +1 Query: 334 ATKEAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGD 510 A EAA++DP + L E+G + G ++KE G V+ G Sbjct: 20 ADGEAAVIDPRRDIDIYLDLAREEGSVIKHVFETHRNEDLLSG-APVLKEETGAKVWHGP 78 Query: 511 DRIGALTKKVE--HNTKFKIGNLNVQCLFTPCHTTGHICYFV--TAPEEGNDSVVFTGDT 678 + + E F+IG ++ L TP HT + Y + + EEG V FTGD Sbjct: 79 NPEKPIQYAAETREGDTFEIGGALLKVLETPGHTEDSLSYVLYDKSFEEGPVGV-FTGDA 137 Query: 679 LFLGGCGR 702 LF+G GR Sbjct: 138 LFIGDVGR 145 >UniRef50_Q4Q2K2 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 518 Score = 41.1 bits (92), Expect = 0.027 Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 6/54 (11%) Frame = +1 Query: 565 GNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV------VFTGDTLFLGGCGRFF 708 G VQ + P HT G + + V + EEG + VFTGD+LF GGCG F Sbjct: 291 GAAKVQAMAAPGHTKGSLVFVVGSAEEGVLTATPARVAVFTGDSLFCGGCGAPF 344 Score = 40.3 bits (90), Expect = 0.046 Identities = 17/36 (47%), Positives = 23/36 (63%) Frame = +1 Query: 289 LPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVE 396 +P DNY YLIV T + A VDP +P+ VL+ +E Sbjct: 165 IPIFGDNYAYLIVSMQTHKVAAVDPADPEMVLRIME 200 >UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bacillaceae|Rep: Uncharacterized protein yqgX - Bacillus subtilis Length = 211 Score = 41.1 bits (92), Expect = 0.027 Identities = 20/55 (36%), Positives = 32/55 (58%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +E + + IG +++ LFTP H+ G + Y+V + +V +GD LF GG GR Sbjct: 109 IEGDGELNIGPFHLETLFTPGHSPGSVSYYVK-----DADLVISGDVLFQGGIGR 158 >UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 209 Score = 40.7 bits (91), Expect = 0.035 Identities = 20/48 (41%), Positives = 30/48 (62%) Frame = +1 Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 ++ +VQ + TP HT G CY++ +EG V+F+GDT+F G GR Sbjct: 119 ELAGFSVQMIETPGHTLGSCCYYL--KDEG---VLFSGDTVFCGSVGR 161 >UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor; n=5; Desulfuromonadales|Rep: Beta-lactamase domain protein precursor - Geobacter uraniumreducens Rf4 Length = 251 Score = 40.7 bits (91), Expect = 0.035 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 20/149 (13%) Frame = +1 Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG- 489 +++ + TKE +VDP + VL AV++ G+ + GGN L++ Sbjct: 57 FILGCEETKEGIVVDPGADADRVLAAVKKSGLAIKYVLNTHGHFDHVGGNRRLLEATGAK 116 Query: 490 LIVYGGD--------DRIGALTKKVEHNTK----------FKIGNLNVQCLFTPCHTTGH 615 L+++ D + A K E++ K G+ ++ L TP HT G Sbjct: 117 LLIHEADVYFLSRAAEVAAAYGLKTENSPKPDGLLEDGMVVIFGSQQLKVLHTPGHTPGG 176 Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 C ++ + EG V TGDTLF G GR Sbjct: 177 CCLYLES--EGK---VITGDTLFADGVGR 200 >UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658; n=15; Actinomycetales|Rep: Uncharacterized protein Rv2581c/MT2658 - Mycobacterium tuberculosis Length = 224 Score = 40.7 bits (91), Expect = 0.035 Identities = 19/50 (38%), Positives = 26/50 (52%) Frame = +1 Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 K +G ++V TP HT G + + V + +VFTGDTLF GR Sbjct: 122 KIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGR 171 >UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; n=6; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 361 Score = 40.3 bits (90), Expect = 0.046 Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 5/136 (3%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPVEPKT--VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 Y YLI D ATKEA +DPV + L + + + L + L+++ Sbjct: 14 YTYLIGDPATKEAVFIDPVNTRVDEYLNLLNKYNLKLKYSLETHAHADHITAS-GLLRQH 72 Query: 484 PGLIVYGGDDRIGA--LTKKVEHNTKFKIGN-LNVQCLFTPCHTTGHICYFVTAPEEGND 654 G G GA +++ G ++ L TP HT G I Y D Sbjct: 73 TGAKT-GIGQACGAQYADYQLKDGVVLAFGQGEEIKVLATPGHTPGSISYL------WRD 125 Query: 655 SVVFTGDTLFLGGCGR 702 V FTGD L + GCGR Sbjct: 126 RV-FTGDALLINGCGR 140 >UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium difficile|Rep: Putative hydrolase - Clostridium difficile (strain 630) Length = 204 Score = 40.3 bits (90), Expect = 0.046 Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 21/150 (14%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKT-VLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 Y++ D+ TK+ A++DP L V+E +N+ G +D IKE+ G Sbjct: 16 YVLGDEKTKKCAVIDPGGSLVETLSFVKENELNIEYIILTHGHGDHIGYVKD-IKEKTGA 74 Query: 493 IVYGGDDRIGALTKK--------------------VEHNTKFKIGNLNVQCLFTPCHTTG 612 V D L K V K ++G L + L TP HT G Sbjct: 75 KVVAHVDEKELLNDKNKNLSYTMRCGAQEFDADIYVNDKDKLELGELKMTFLHTPGHTQG 134 Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +C V + +FTGDTLF G GR Sbjct: 135 CMCIRV-------EDEMFTGDTLFAGSIGR 157 >UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n=1; unknown|Rep: UPI00015BCB57 UniRef100 entry - unknown Length = 217 Score = 39.9 bits (89), Expect = 0.061 Identities = 17/55 (30%), Positives = 31/55 (56%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 ++ K I +++++ + TP HT G C+++ + + + GDTLF GG GR Sbjct: 116 IKDGDKLSIASVDIEIIHTPGHTPGGCCFYLP-----SQNTLIAGDTLFKGGVGR 165 >UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrolase; n=1; Vibrio vulnificus YJ016|Rep: Putative hydroxyacylglutathione hydrolase - Vibrio vulnificus (strain YJ016) Length = 247 Score = 39.9 bits (89), Expect = 0.061 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 1/137 (0%) Frame = +1 Query: 295 ALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLI 474 +L DNY++++ DK+ +A ++DP E + ++ +++ + L G L Sbjct: 10 SLIDNYIWILFDKS--KAIVIDPGESEKIINFLDKNNLTLEFIFLTHGHCDHTKGVFSLK 67 Query: 475 KERPGLIVYGGDD-RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGN 651 ++ P ++ +G ++ + + N L P HT HI Sbjct: 68 EKFPNASLFVPIGLELGLGESIIKEGDELNLLNSTFNVLELPGHTDNHIGIMY------K 121 Query: 652 DSVVFTGDTLFLGGCGR 702 D++ F GD LF GCGR Sbjct: 122 DNL-FCGDVLFSAGCGR 137 >UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1; Syntrophus aciditrophicus SB|Rep: Hydroxyacylglutathione hydrolase W - Syntrophus aciditrophicus (strain SB) Length = 257 Score = 39.9 bits (89), Expect = 0.061 Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 19/150 (12%) Frame = +1 Query: 310 YMYLIVDKATKEAAIVDPVEP-KTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 + YL+ D T +A ++DP + +L E+ + + GN ++ Sbjct: 62 FAYLVGDSETGDALVIDPADNIDGILATAEKNNLRIKYIVNTHGHIDHISGNREMKSRTD 121 Query: 487 G-LIVYGGDDRIGALTKK-----------------VEHNTKFKIGNLNVQCLFTPCHTTG 612 +I++ GD R+ T V+ +G ++++ + TP H+ G Sbjct: 122 APIIIHEGDARMLGNTSPMLLHMFGAEDSPPADMTVKDGDTITVGKISLKVIHTPGHSPG 181 Query: 613 HICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +C ++ VFTGDTLF+ GR Sbjct: 182 GMCLYIKG-------FVFTGDTLFVESVGR 204 >UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11; Gammaproteobacteria|Rep: Beta-lactamase domain protein - Enterobacter sp. 638 Length = 215 Score = 39.9 bits (89), Expect = 0.061 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +GN+ +Q L P HT GHI +F + ++ +GD +F GG GR Sbjct: 119 VGNVTLQILHCPGHTPGHIVFF-----DDQSRLLISGDVIFKGGVGR 160 >UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein; n=2; Corynebacterineae|Rep: Metallo-beta-lactamase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 210 Score = 39.9 bits (89), Expect = 0.061 Identities = 22/56 (39%), Positives = 30/56 (53%) Frame = +1 Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 + VE K G + V L TP H+ G +C+ + PE + V +GDTLF GG G Sbjct: 106 RAVEDGLVLKAGEIEVHALHTPGHSPGSVCWSI--PEL---NAVISGDTLFQGGPG 156 >UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120; Bacteria|Rep: Uncharacterized protein ycbL - Escherichia coli (strain K12) Length = 215 Score = 39.5 bits (88), Expect = 0.081 Identities = 18/47 (38%), Positives = 27/47 (57%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 IGN+ +Q L P HT GH+ +F + ++ +GD +F GG GR Sbjct: 119 IGNVTLQVLHCPGHTPGHVVFF-----DDRAKLLISGDVIFKGGVGR 160 >UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep: Beta-lactamase-like - Moorella thermoacetica (strain ATCC 39073) Length = 207 Score = 39.1 bits (87), Expect = 0.11 Identities = 41/151 (27%), Positives = 59/151 (39%), Gaps = 22/151 (14%) Frame = +1 Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGL 492 YLI T E A++DP E + +L A E G+N+ G N IK G Sbjct: 16 YLIGCPETGEGAVIDPGAEGERILAAAREAGLNIKQIINTHGHGDHIGAN-GAIKAATGA 74 Query: 493 --------------------IVYGGDDRIGALTKKVEHNTKFKIGN-LNVQCLFTPCHTT 609 ++ G + + +E + IG + ++ + TP HT Sbjct: 75 AILIHRADAHYLTDPGRNLSVLLGSREASPPADRLLEEDDTIAIGKTVTLRVIHTPGHTP 134 Query: 610 GHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 G IC + +VFTGDTLF G GR Sbjct: 135 GGICLH-------GEGLVFTGDTLFAGSIGR 158 >UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Rep: Beta-lactamase-like - Desulfitobacterium hafniense (strain DCB-2) Length = 205 Score = 39.1 bits (87), Expect = 0.11 Identities = 21/55 (38%), Positives = 31/55 (56%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +E ++GNLN+ + TP HT G +C+ + EG + +GDTLF G GR Sbjct: 109 LEDGQILQVGNLNLTVIATPGHTLGGVCFLTS---EG----LLSGDTLFDGSIGR 156 >UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1; Bifidobacterium adolescentis L2-32|Rep: Putative uncharacterized protein - Bifidobacterium adolescentis L2-32 Length = 264 Score = 39.1 bits (87), Expect = 0.11 Identities = 34/145 (23%), Positives = 58/145 (40%), Gaps = 5/145 (3%) Frame = +1 Query: 280 VKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKA-VEEQGVNLXXXXXXXXXXXXA- 453 +++ N YL+VD T++A +VDP + L+A ++ G L Sbjct: 23 IEVAAGAMKNNNYLVVDPVTRQALLVDPAWQRDKLEAALQRAGATLSAIAITHAHFDHVH 82 Query: 454 -GGNEDLIKERPGLIVYGGDDRIGALTKKVE--HNTKFKIGNLNVQCLFTPCHTTGHICY 624 G + P + + G ++ T +G L ++ + P HT G +CY Sbjct: 83 LAGELSAAHDCPVWMSQCEIETSGFDLPRLLAIDETPRTLGALRIEPILAPGHTPGCLCY 142 Query: 625 FVTAPEEGNDSVVFTGDTLFLGGCG 699 + +F GD LF+ GCG Sbjct: 143 RI-------GGHLFAGDVLFIEGCG 160 >UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clostridiaceae|Rep: Beta-lactamase domain protein - Alkaliphilus metalliredigens QYMF Length = 206 Score = 39.1 bits (87), Expect = 0.11 Identities = 21/47 (44%), Positives = 25/47 (53%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 IGNL + L TP H+ G +C + VVFTGDTLF GR Sbjct: 118 IGNLKLHVLHTPGHSPGGVCI-------RGEGVVFTGDTLFANSIGR 157 >UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; Eubacterium ventriosum ATCC 27560|Rep: Putative uncharacterized protein - Eubacterium ventriosum ATCC 27560 Length = 207 Score = 39.1 bits (87), Expect = 0.11 Identities = 20/50 (40%), Positives = 30/50 (60%) Frame = +1 Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 K + +N+ + TP HT G CY++ E N+ ++F+GDTLF G GR Sbjct: 117 KITLAGINMTFIATPGHTPGSGCYYL----EDNE-ILFSGDTLFHGSRGR 161 >UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: YqgX - Bacillus sp. B14905 Length = 214 Score = 39.1 bits (87), Expect = 0.11 Identities = 21/55 (38%), Positives = 27/55 (49%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 ++ +F+I N Q +FTP H+ G I Y ND GDTLF G GR Sbjct: 114 IKKEQQFEISNFVFQAVFTPGHSPGSISYVFE-----NDGFAIVGDTLFEQGVGR 163 >UniRef50_Q4WA58 Cluster: Metallo-beta-lactamase domain protein; n=4; Trichocomaceae|Rep: Metallo-beta-lactamase domain protein - Aspergillus fumigatus (Sartorya fumigata) Length = 330 Score = 39.1 bits (87), Expect = 0.11 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 2/109 (1%) Frame = +1 Query: 361 PVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLI--VYGGDDRIGALTK 534 P+ ++ ++ +++ GG DLI P L VY +G K Sbjct: 73 PIWLSRIVGVLQSNNISISHILLTHWHGDHTGGVPDLISYNPTLAEHVYKNLPDLGQ--K 130 Query: 535 KVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTL 681 +E F + V+ +FTP H+ H+C+ + EE N +FTGD + Sbjct: 131 PIEDGQIFAVEGATVRAVFTPGHSVDHMCFLL---EEEN--ALFTGDNV 174 >UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2; Anaeromyxobacter|Rep: Beta-lactamase domain protein - Anaeromyxobacter sp. Fw109-5 Length = 217 Score = 38.7 bits (86), Expect = 0.14 Identities = 20/49 (40%), Positives = 29/49 (59%) Frame = +1 Query: 556 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 F++G + + TP H+ G IC F P+E ++F+GDTLF G GR Sbjct: 116 FRVGASEGRVIHTPGHSPGSICLFF--PQE---RLLFSGDTLFAGSVGR 159 >UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; Reinekea sp. MED297|Rep: Hydroxyacylglutathione hydrolase - Reinekea sp. MED297 Length = 258 Score = 38.7 bits (86), Expect = 0.14 Identities = 28/133 (21%), Positives = 50/133 (37%), Gaps = 2/133 (1%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERP 486 NY +L+ T++AA +DP + ++ ++ + + G L +E Sbjct: 14 NYNHLVYCPTTQQAAAIDPFDANHIVDIAKKHSLTIIQIWLTHEHGDHIRGLNSL-RELT 72 Query: 487 GLIVYGGDDRIGALTKKV--EHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 G + G + E + ++G + TP HT GH + P+ Sbjct: 73 GAKSFAPMTCNGLFESDIWLEDGQEVRLGKETLTHYLTPGHTPGHGVFLYQDPQLSERDF 132 Query: 661 VFTGDTLFLGGCG 699 + DTLF G G Sbjct: 133 LVCADTLFNAGVG 145 >UniRef50_A4S568 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 476 Score = 38.7 bits (86), Expect = 0.14 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%) Frame = +1 Query: 115 NFILFKKTYSMLARFVNSLPSGLSQRITKLYFRALIRNQREAHSS-QEDHQYKNMDVKIL 291 N L +KTY++ ARF S +G QR L A+++ EAH D +YK+ + Sbjct: 236 NLWLRRKTYTLAARFAESKHTGDEQRELNLEMSAMLQYFHEAHHGLYHDVRYKHQPEVVQ 295 Query: 292 PAL-QDNYMYLIVDKATKEAAIVDPV 366 L + Y+ ++ D K+ + + P+ Sbjct: 296 KILFETGYLKVVQDARGKDTSQLAPL 321 >UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37; Actinomycetales|Rep: Beta-lactamase-like - Frankia sp. (strain CcI3) Length = 216 Score = 38.3 bits (85), Expect = 0.19 Identities = 20/41 (48%), Positives = 25/41 (60%) Frame = +1 Query: 577 VQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 ++ L TP H+ G IC F E D V+F+GDTLF GG G Sbjct: 125 LRVLHTPGHSPGGICLF---GEINGDPVLFSGDTLFRGGPG 162 >UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1; Saccharophagus degradans 2-40|Rep: Hydroxyacylglutathione hydrolase - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 272 Score = 38.3 bits (85), Expect = 0.19 Identities = 36/153 (23%), Positives = 62/153 (40%), Gaps = 10/153 (6%) Frame = +1 Query: 274 MDVKILPALQDNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXA 453 + V +P Q NY++++ + +VDP V++ + + + + Sbjct: 9 VSVHPIPIYQGNYVWVMRHTSQNSVVVVDPGSASEVIEYITQHELTIASIIITHSHWDHV 68 Query: 454 GGNEDLIKE----RPGLIVYGGDDRIGALTKKVEHNTKFKIGN----LNVQCLFTPCHTT 609 G +L R V G I +T VE + ++ ++Q + TP H Sbjct: 69 TGIAELCANLQLWRDEEPVVYGPSVIQDVTHPVEDGDRIELCKGVDVPSLQVIATPGHMP 128 Query: 610 GHICYFV--TAPEEGNDSVVFTGDTLFLGGCGR 702 H+ Y + T P+ +F GDTLF GCGR Sbjct: 129 EHLSYLLPLTTPK------LFCGDTLFSCGCGR 155 >UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium phytofermentans ISDg|Rep: Beta-lactamase-like - Clostridium phytofermentans ISDg Length = 216 Score = 38.3 bits (85), Expect = 0.19 Identities = 18/50 (36%), Positives = 28/50 (56%) Frame = +1 Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 K + ++ L TP HT G +CY++ P+E ++ +GDTLF GR Sbjct: 117 KIQFADIEFVVLHTPGHTKGSVCYYI--PDE---QILLSGDTLFFESVGR 161 >UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative uncharacterized protein - Fulvimarina pelagi HTCC2506 Length = 289 Score = 38.3 bits (85), Expect = 0.19 Identities = 36/138 (26%), Positives = 58/138 (42%), Gaps = 7/138 (5%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 NY Y++ D +T +A ++DP E + +L ++ + L I Sbjct: 38 NYAYIVADFSTGDAVVIDPGWEAEFLLSSLAAFRLRLAGICLTHGHRDHWMA-APAIARA 96 Query: 484 PGLIVYGGD---DRIGALT---KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEE 645 G V+ D G + + +E G++ ++ L TP HT G I Y + A Sbjct: 97 TGCPVHMSRLDADHFGFASNGLRPLEAPVALAFGSIGIEALETPGHTAGSISYRIGA--- 153 Query: 646 GNDSVVFTGDTLFLGGCG 699 +F+GDTLF GCG Sbjct: 154 ----CLFSGDTLFSEGCG 167 >UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bacteria|Rep: Beta-lactamase domain protein - Pelobacter propionicus (strain DSM 2379) Length = 253 Score = 38.3 bits (85), Expect = 0.19 Identities = 19/55 (34%), Positives = 30/55 (54%) Frame = +1 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684 G TK ++ N +GN +Q L TP H+ GH+C++ E +FTGD ++ Sbjct: 127 GTPTKVLKDNDVIDMGNRCIQVLHTPGHSPGHMCFW-----EKERGYLFTGDLVY 176 >UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium cellulolyticum H10|Rep: Beta-lactamase-like - Clostridium cellulolyticum H10 Length = 208 Score = 38.3 bits (85), Expect = 0.19 Identities = 20/55 (36%), Positives = 30/55 (54%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 + K+G L+ + + TP HT G IC V ++++F+GDTLF G GR Sbjct: 108 LREGNSIKVGELDFKIIHTPGHTCGSICIQV-------ENLLFSGDTLFKFGYGR 155 >UniRef50_Q7QZA0 Cluster: GLP_567_43928_43275; n=1; Giardia lamblia ATCC 50803|Rep: GLP_567_43928_43275 - Giardia lamblia ATCC 50803 Length = 217 Score = 38.3 bits (85), Expect = 0.19 Identities = 20/47 (42%), Positives = 25/47 (53%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 I + ++ + TP HT G +C A D VV TGDTLF G GR Sbjct: 128 IDGITLEVIHTPGHTPGSVCLLSDA-----DKVVCTGDTLFANGYGR 169 >UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Beta-lactamase-like - Herpetosiphon aurantiacus ATCC 23779 Length = 369 Score = 37.9 bits (84), Expect = 0.25 Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 1/121 (0%) Frame = +1 Query: 343 EAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519 +A ++D ++P L+ + +G L + L + + R Sbjct: 140 QALVIDASLDPAVYLQLAQARGWQLQAVLDTHIHADHLSRSRQLAELSGATFYLPANQRN 199 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 + + + N + ++G +Q L TP HT + Y + + S +F+GDTLFL G Sbjct: 200 SGVYQPISANMQIQLGAATIQALATPGHTWESMSYLL------DGSHLFSGDTLFLAAVG 253 Query: 700 R 702 R Sbjct: 254 R 254 >UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily protein; n=11; Francisella tularensis|Rep: Metallo-beta-lactamase superfamily protein - Francisella tularensis subsp. tularensis (strain WY96-3418) Length = 252 Score = 37.9 bits (84), Expect = 0.25 Identities = 30/133 (22%), Positives = 54/133 (40%), Gaps = 2/133 (1%) Frame = +1 Query: 307 NYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDL--IKE 480 NY YL+ DK+ A ++DP++ + + + + L G + L I Sbjct: 14 NYQYLLYDKS--HAIVIDPLKSDIFAEFIAKNKLQLEAILITHKHGDHIAGVKKLLAIYL 71 Query: 481 RPGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV 660 + Y G+D V+ + +G + + ++ P H H+C+ + Sbjct: 72 NAKVYAYTGNDLFKP-DIYVKDGSFINLGFTSFRVMYIPGHIDDHVCFLFE-----QERA 125 Query: 661 VFTGDTLFLGGCG 699 +F GDTLF G G Sbjct: 126 LFCGDTLFNAGVG 138 >UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clostridium thermocellum ATCC 27405|Rep: Beta-lactamase-like protein - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 201 Score = 37.9 bits (84), Expect = 0.25 Identities = 21/47 (44%), Positives = 26/47 (55%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +G L+ + + TP H+ G IC V VVFTGDTLF G GR Sbjct: 116 VGGLDFEIIHTPGHSAGGICIKV-------GDVVFTGDTLFCMGIGR 155 >UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; Methylobacterium extorquens PA1|Rep: Hydroxyacylglutathione hydrolase - Methylobacterium extorquens PA1 Length = 158 Score = 37.5 bits (83), Expect = 0.33 Identities = 19/47 (40%), Positives = 24/47 (51%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +G L TP H H+ Y+ + VVF+GDTLF GCGR Sbjct: 3 VGGLTAAVWETPGHCADHVTYYFA-----DAGVVFSGDTLFTLGCGR 44 >UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 214 Score = 37.5 bits (83), Expect = 0.33 Identities = 22/61 (36%), Positives = 31/61 (50%) Frame = +1 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 G + ++ +G L + + TP HT G CY+ EG+D +V GDTLF G G Sbjct: 107 GRIDHLLDDGDTVTLGELELTFVATPGHTPGQGCYW-----EGDDIIV--GDTLFAGSVG 159 Query: 700 R 702 R Sbjct: 160 R 160 >UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bacteria|Rep: Beta-lactamase domain protein - Desulfotomaculum reducens MI-1 Length = 205 Score = 37.5 bits (83), Expect = 0.33 Identities = 21/48 (43%), Positives = 28/48 (58%) Frame = +1 Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +IGN+ ++ L TP HT G IC + G D +F+GDTLF GR Sbjct: 117 QIGNITLEVLHTPGHTPGGICL-----KAGKD--LFSGDTLFAQSIGR 157 >UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Hydroxyacylglutathione hydrolase W - Candidatus Desulfococcus oleovorans Hxd3 Length = 220 Score = 37.5 bits (83), Expect = 0.33 Identities = 19/55 (34%), Positives = 27/55 (49%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 ++H +G + L TP HT G IC ++ +F GDTLF+G GR Sbjct: 118 LQHGEAVVLGQTTLTVLHTPGHTPGSICLYMPGH-------LFAGDTLFVGSAGR 165 >UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1; Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione hydrolase - Dictyostelium discoideum AX4 Length = 292 Score = 37.5 bits (83), Expect = 0.33 Identities = 20/49 (40%), Positives = 29/49 (59%) Frame = +1 Query: 553 KFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 +F IG+L V+ + TP HT + Y++ NDS VF GDT+F+ G Sbjct: 132 RFTIGSLQVRVISTPGHTPACVSYYIE-----NDS-VFVGDTMFMPDVG 174 >UniRef50_UPI00006CD5DA Cluster: TNFR/NGFR cysteine-rich region family protein; n=1; Tetrahymena thermophila SB210|Rep: TNFR/NGFR cysteine-rich region family protein - Tetrahymena thermophila SB210 Length = 2129 Score = 37.1 bits (82), Expect = 0.43 Identities = 14/32 (43%), Positives = 19/32 (59%) Frame = -1 Query: 624 ITYMPSCMTGCKKTLYIQVTDFKLCIVLNFFC 529 I Y SC+ C K +Y+ T +K CI NF+C Sbjct: 1846 IKYNSSCIVECPKQMYMTQTPYKQCIECNFYC 1877 >UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; n=1; Porphyromonas gingivalis|Rep: Metallo-beta-lactamase family protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 214 Score = 37.1 bits (82), Expect = 0.43 Identities = 18/48 (37%), Positives = 27/48 (56%) Frame = +1 Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 ++G ++ LF P H+ GH+ ++ P+ VFTGD LF G GR Sbjct: 123 QLGESIIKVLFVPGHSPGHLAFY--CPQA---QAVFTGDALFAGDMGR 165 >UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1; Sphingomonas wittichii RW1|Rep: Hydroxyacylglutathione hydrolase - Sphingomonas wittichii RW1 Length = 256 Score = 37.1 bits (82), Expect = 0.43 Identities = 34/134 (25%), Positives = 54/134 (40%), Gaps = 6/134 (4%) Frame = +1 Query: 316 YLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLI 495 YL+ + EAA +DP + VL+ G+ + AG N L +E G Sbjct: 17 YLVWCPDSGEAAAIDPYQLDLVLETARANGLTITRIVNTHEHWDHAGRNAQL-REATGAE 75 Query: 496 VYGGDDRIGALTKKVEH----NTKFKIG-NLNVQCLFTPCHTTGHICYFVTAPEEGNDS- 657 V G + + V+H + +G + ++ + P HT H+ + G D Sbjct: 76 VLAPRAAAGVI-ETVDHMLAEGDEIVVGTSCRLRVIEMPGHTMTHVGLLGEGADRGEDEP 134 Query: 658 VVFTGDTLFLGGCG 699 + GDTLF G G Sbjct: 135 FLLCGDTLFGAGVG 148 >UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; n=4; Desulfuromonadales|Rep: Metallo-beta-lactamase family protein - Geobacter sulfurreducens Length = 209 Score = 36.7 bits (81), Expect = 0.57 Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 20/149 (13%) Frame = +1 Query: 316 YLIVDKATKEAAIVDP-VEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPG- 489 +++ + ++E IVDP E +L+ V E G+ + GGN +++ Sbjct: 16 FILGCEQSREGVIVDPGAESGRILERVGELGLKVGMVINTHGHFDHVGGNRKVLEATGAK 75 Query: 490 LIVYGGD----DRIG--------------ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGH 615 L+V+ D DR A +E +G L+++ L TP HT G Sbjct: 76 LLVHRDDVHFLDRAADVAAMYGLDTENSPAPDSLLEDGMTLSVGTLSLRVLHTPGHTPGG 135 Query: 616 ICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 C + EG V+ TGDTLF GR Sbjct: 136 CCLLL----EGEGKVL-TGDTLFEESVGR 159 >UniRef50_Q1VZM6 Cluster: Metallo-beta-lactamase superfamily protein; n=10; Bacteroidetes|Rep: Metallo-beta-lactamase superfamily protein - Psychroflexus torquis ATCC 700755 Length = 447 Score = 36.7 bits (81), Expect = 0.57 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 3/121 (2%) Frame = +1 Query: 349 AIVDPV-EPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRIGA 525 A+VDP +P+ EEQ + + + +E G +Y +GA Sbjct: 25 ALVDPARDPQAYYDYAEEQKAKIVAVFETHPHADFVSSHLQIHQET-GAAIYVSK-LVGA 82 Query: 526 --LTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 + + + K+ + +C+ TP H+ I +++ FTGDTLF+G G Sbjct: 83 DYPHQSFDEGEELKMNGITFKCIHTPGHSPDGITVHAVDKATTKEAI-FTGDTLFIGDVG 141 Query: 700 R 702 R Sbjct: 142 R 142 >UniRef50_A1D100 Cluster: FAD binding domain protein; n=4; Trichocomaceae|Rep: FAD binding domain protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 1100 Score = 36.7 bits (81), Expect = 0.57 Identities = 18/50 (36%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Frame = +1 Query: 208 FRALIRNQREAHSSQEDH--QYKNMDVKILPALQDNYMYLIVDKATKEAA 351 F A++R R HSS E+H ++K + + +P+LQ YMY ++T A Sbjct: 648 FSAVLRRWRHRHSSPEEHEAEFKRYEKRDVPSLQRAYMYAFAVQSTVHIA 697 >UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; Deltaproteobacteria|Rep: Hydroxyacylglutathione hydrolase - Syntrophus aciditrophicus (strain SB) Length = 235 Score = 36.3 bits (80), Expect = 0.76 Identities = 38/135 (28%), Positives = 54/135 (40%) Frame = +1 Query: 304 DNYMYLIVDKATKEAAIVDPVEPKTVLKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKER 483 DN YLI T A VD + +L +E++ + L GNE L+K Sbjct: 14 DNLGYLIFGDRT--AMAVDGGAVEDILSFLEKRRLELRWVVNTHSHYDHTSGNEALLKYS 71 Query: 484 PGLIVYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVV 663 + D A+ ++E K +Q TP HT IC+ D+++ Sbjct: 72 RARFI---DCAALAVLGRLELEGKI------IQVYATPGHTRDSICFHT-------DTIL 115 Query: 664 FTGDTLFLGGCGRFF 708 TGDTLF G G F Sbjct: 116 LTGDTLFNGTVGNCF 130 >UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein; n=1; Myxococcus xanthus DK 1622|Rep: Metallo-beta-lactamase family protein - Myxococcus xanthus (strain DK 1622) Length = 483 Score = 36.3 bits (80), Expect = 0.76 Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 2/122 (1%) Frame = +1 Query: 343 EAAIVDPVEPKTV-LKAVEEQGVNLXXXXXXXXXXXXAGGNEDLIKERPGLIVYGGDDRI 519 EA +VDP V L + Q + L G L + +V G Sbjct: 23 EALVVDPRRDVDVYLDVLRRQELRLRYVLQTHRQEDFVEGTSALARLAGAQVVAGRHPIT 82 Query: 520 GALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTA-PEEGNDSVVFTGDTLFLGGC 696 G ++ + +G L + L TP HT + + V P VFTGD L G Sbjct: 83 GHADVRMGERERLHLGALTLVALHTPGHTPESMSWAVYLDPHHAQAWGVFTGDALLAGET 142 Query: 697 GR 702 GR Sbjct: 143 GR 144 >UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalteromonas atlantica T6c|Rep: Beta-lactamase-like - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 288 Score = 36.3 bits (80), Expect = 0.76 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Frame = +1 Query: 514 RIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFL-- 687 R A K ++ + G+ + C+ TP HT+ + Y + D VF GDTLF+ Sbjct: 116 RFDAFDKLLQDGESLQFGSATLVCMSTPGHTSDSLSYII-------DDNVFVGDTLFMPD 168 Query: 688 GGCGR 702 GG R Sbjct: 169 GGTAR 173 >UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain protein - Shewanella sediminis HAW-EB3 Length = 354 Score = 36.3 bits (80), Expect = 0.76 Identities = 20/47 (42%), Positives = 24/47 (51%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +G L + + TP HT IC + VFTGDTL LGG GR Sbjct: 101 VGKLRLTIMHTPGHTADSICIVMK-------DRVFTGDTLLLGGTGR 140 >UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1; Pseudoalteromonas tunicata D2|Rep: Beta-lactamase-like protein - Pseudoalteromonas tunicata D2 Length = 283 Score = 36.3 bits (80), Expect = 0.76 Identities = 20/48 (41%), Positives = 26/48 (54%) Frame = +1 Query: 556 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCG 699 F +G V L TP HT+ +CY V +GN VF GDT+F+ G Sbjct: 128 FPLGQFTVTVLATPGHTSDSVCYVV----DGN---VFVGDTVFMPDSG 168 >UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative uncharacterized protein - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 186 Score = 36.3 bits (80), Expect = 0.76 Identities = 18/55 (32%), Positives = 27/55 (49%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 +E K+G + F P HT GH+ ++ N +++TGD LF G GR Sbjct: 84 LEGGEVLKLGEDEFEVRFAPGHTPGHVMFY-----NKNHGLLWTGDVLFKGSIGR 133 >UniRef50_A3L9H1 Cluster: Putative uncharacterized protein; n=1; Pseudomonas aeruginosa 2192|Rep: Putative uncharacterized protein - Pseudomonas aeruginosa 2192 Length = 270 Score = 36.3 bits (80), Expect = 0.76 Identities = 21/43 (48%), Positives = 22/43 (51%) Frame = +1 Query: 556 FKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684 F IG L Q L P HT I Y V N+ VVF GDTLF Sbjct: 129 FYIGPLRTQALAVPGHTPADIAYLV------NNEVVFVGDTLF 165 >UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; Sulfolobus|Rep: Putative uncharacterized protein - Sulfolobus solfataricus Length = 209 Score = 36.3 bits (80), Expect = 0.76 Identities = 19/55 (34%), Positives = 28/55 (50%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 V+ + ++G ++ + TP HT G IC + +FTGDTLF G GR Sbjct: 110 VKEGDEIELGGEKLKIIETPGHTMGSICIIA-------NGYIFTGDTLFYGTVGR 157 >UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative uncharacterized protein - Uncultured methanogenic archaeon RC-I Length = 208 Score = 36.3 bits (80), Expect = 0.76 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Frame = +1 Query: 496 VYGGDDRIGALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGD 675 ++G D + ++ + +G++ ++ + TP HT G IC + E +FTGD Sbjct: 90 MFGSDSPELKVDMVLKDGDEIDLGDVKLRVIHTPGHTPGSICLY-----EPVSKAMFTGD 144 Query: 676 TLF-LGGCGR 702 T+F GG GR Sbjct: 145 TVFEEGGFGR 154 >UniRef50_A3CRI7 Cluster: Beta-lactamase domain protein; n=3; Methanomicrobiales|Rep: Beta-lactamase domain protein - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 200 Score = 36.3 bits (80), Expect = 0.76 Identities = 22/50 (44%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Frame = +1 Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGC-GRF 705 +IGNL V + TP HT G IC + A + ++F+GDT+F GG GR+ Sbjct: 106 RIGNLCV--IHTPGHTPGGICLYNEA-----EKLLFSGDTVFTGGSFGRY 148 >UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase family; n=6; Proteobacteria|Rep: Zn-dependent hydrolases, glyoxylase family - Idiomarina loihiensis Length = 292 Score = 35.9 bits (79), Expect = 1.00 Identities = 17/51 (33%), Positives = 28/51 (54%) Frame = +1 Query: 532 KKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684 K ++ F +G++ ++ + TP HT I Y + N++ VF GDTLF Sbjct: 127 KLLQDGETFHLGSMTIRVIHTPGHTPADIAYVI------NENKVFVGDTLF 171 >UniRef50_Q0RV20 Cluster: Possible hydrolase; n=1; Rhodococcus sp. RHA1|Rep: Possible hydrolase - Rhodococcus sp. (strain RHA1) Length = 454 Score = 35.9 bits (79), Expect = 1.00 Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 1/48 (2%) Frame = +1 Query: 562 IGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSV-VFTGDTLFLGGCGR 702 +G L ++ L TP HT H+C+ + +G+ V VFTG +L +G R Sbjct: 101 LGGLRLRALTTPGHTHEHLCFLLL---DGDTEVGVFTGGSLIVGSAAR 145 >UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Beta-lactamase domain protein - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 199 Score = 35.9 bits (79), Expect = 1.00 Identities = 19/48 (39%), Positives = 27/48 (56%) Frame = +1 Query: 559 KIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 + G+LN + + TP HT G C+ G D ++F+GDTLF GR Sbjct: 113 EFGDLNFKVIHTPGHTPGSSCFLY-----GGD-ILFSGDTLFKDSYGR 154 >UniRef50_A1HQX4 Cluster: Beta-lactamase domain protein; n=1; Thermosinus carboxydivorans Nor1|Rep: Beta-lactamase domain protein - Thermosinus carboxydivorans Nor1 Length = 332 Score = 35.9 bits (79), Expect = 1.00 Identities = 16/46 (34%), Positives = 24/46 (52%) Frame = +1 Query: 538 VEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGD 675 V + IG+ C+ TP HT GH+C + E N ++F+GD Sbjct: 149 VREGYRLVIGDYEFTCITTPGHTPGHVCLY-----EPNRKILFSGD 189 >UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 215 Score = 35.9 bits (79), Expect = 1.00 Identities = 19/60 (31%), Positives = 29/60 (48%) Frame = +1 Query: 523 ALTKKVEHNTKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLFLGGCGR 702 A + +E G + + + TP HT GH+ + PE + +F GDT+F G GR Sbjct: 112 AADRTLEEGDVLDFGPIRLSVIETPGHTPGHVSVYF--PEAKS---IFVGDTIFAGSIGR 166 >UniRef50_A4QPZ2 Cluster: Putative uncharacterized protein; n=4; Dikarya|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 531 Score = 35.9 bits (79), Expect = 1.00 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Frame = +1 Query: 172 PSGLSQRITKLYFRALIR--NQREAHSSQEDHQYKNMDVKILPALQDNYMYLIVDKATKE 345 P ++Q ++Y AL+R N + E + +D++ILP L Y + VDK T Sbjct: 33 PQLVNQAHPEIYMEALVRYPNDESIDQADEKRLVRKLDMRILPLLGVCYFFYYVDKTTLS 92 Query: 346 AAIVDPVEPKTVLKAVE 396 A + ++ LK E Sbjct: 93 YAAIFGLKEGLGLKGEE 109 >UniRef50_UPI00015978D7 Cluster: NrsD; n=1; Bacillus amyloliquefaciens FZB42|Rep: NrsD - Bacillus amyloliquefaciens FZB42 Length = 919 Score = 35.5 bits (78), Expect = 1.3 Identities = 16/45 (35%), Positives = 27/45 (60%) Frame = +1 Query: 550 TKFKIGNLNVQCLFTPCHTTGHICYFVTAPEEGNDSVVFTGDTLF 684 T IG+++++ + +P HTTG +C D+ +FTGDT+F Sbjct: 828 TVLNIGDISLKIILSPGHTTGSVCVLY-------DNFLFTGDTIF 865 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 640,116,599 Number of Sequences: 1657284 Number of extensions: 12012145 Number of successful extensions: 29035 Number of sequences better than 10.0: 299 Number of HSP's better than 10.0 without gapping: 27852 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 28759 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 57851245060 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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