Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0148
(724 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH... 379 e-104
UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 379 e-104
UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s... 362 5e-99
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC... 300 2e-80
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 296 4e-79
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 289 5e-77
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;... 285 1e-75
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 280 2e-74
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 272 8e-72
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 238 9e-62
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 237 3e-61
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 229 7e-59
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 227 3e-58
UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut... 226 4e-58
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 225 9e-58
UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 compone... 224 2e-57
UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E... 223 3e-57
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 221 1e-56
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 221 2e-56
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 217 2e-55
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 216 5e-55
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 215 9e-55
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 215 9e-55
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 214 2e-54
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 213 3e-54
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 213 5e-54
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 211 1e-53
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 210 2e-53
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 209 6e-53
UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000... 206 3e-52
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 206 3e-52
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 206 4e-52
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 206 6e-52
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte... 205 1e-51
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 204 1e-51
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E... 204 2e-51
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 204 2e-51
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 203 3e-51
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 203 3e-51
UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;... 200 4e-50
UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil... 200 4e-50
UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 198 1e-49
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 197 3e-49
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 194 1e-48
UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 194 2e-48
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 193 4e-48
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 191 1e-47
UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,... 190 2e-47
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 190 3e-47
UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 189 5e-47
UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 188 1e-46
UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo... 188 1e-46
UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 188 2e-46
UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 184 1e-45
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 183 3e-45
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 183 3e-45
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 182 6e-45
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p... 182 1e-44
UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 179 6e-44
UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 179 7e-44
UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 177 2e-43
UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s... 177 3e-43
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 174 2e-42
UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdello... 169 5e-41
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 164 2e-39
UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 163 4e-39
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 162 7e-39
UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 161 2e-38
UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma... 161 2e-38
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone... 159 8e-38
UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh... 155 1e-36
UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ... 155 1e-36
UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ... 151 1e-35
UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lu... 128 1e-28
UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;... 103 3e-21
UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura... 97 4e-19
UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_UPI0000E46CA4 Cluster: PREDICTED: hypothetical protein,... 73 7e-12
UniRef50_Q9KJ66 Cluster: Irb5; n=1; Vibrio cholerae|Rep: Irb5 - ... 38 0.33
UniRef50_A3Z1Y0 Cluster: Serine protease, subtilase family prote... 35 1.8
UniRef50_Q1MRZ5 Cluster: Hyphotheical protein; n=1; Lawsonia int... 35 2.3
UniRef50_Q00160 Cluster: Uncharacterized gene 37 protein; n=1; I... 34 4.1
UniRef50_Q0TE31 Cluster: Putative membrane protein; n=10; Entero... 33 5.4
UniRef50_Q7ULX8 Cluster: NifS-like aminotranfserase-putative cys... 33 7.1
UniRef50_A0JY86 Cluster: Putative uncharacterized protein; n=2; ... 33 7.1
UniRef50_Q2NB23 Cluster: Protein-tyrosine-phosphatase; n=6; Alph... 33 9.4
UniRef50_Q1D6W3 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4
UniRef50_Q029Y8 Cluster: NHL repeat containing protein; n=2; Bac... 33 9.4
UniRef50_Q9ST86 Cluster: CAA303711.1 protein; n=2; Oryza sativa|... 33 9.4
UniRef50_A5DBM7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4
>UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH
protein - Homo sapiens (Human)
Length = 640
Score = 379 bits (933), Expect = e-104
Identities = 173/241 (71%), Positives = 204/241 (84%), Gaps = 1/241 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IG+EFMFIN LEQC WIRQ+ E P + + ++KR +LARL RST FE FL +KWSSEK
Sbjct: 123 HIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEK 182
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AG 360
RFGLEGCE+LIPA+K +ID S++ GV+ +IMGMPHRGRLNVLANV RK L Q+F QF +
Sbjct: 183 RFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSK 242
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
LEA D+GSGDVKYHLG Y R+NRVT++NI L++ ANPSHLEA DPVV GKT+AEQFY G
Sbjct: 243 LEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCG 302
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSR 720
D EGKKVMSILLHGDAAFAGQG+V+ET HLSDLP+YTTHGT+H+V NNQIGFTTDPR +R
Sbjct: 303 DTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMAR 362
Query: 721 S 723
S
Sbjct: 363 S 363
>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=77; Eumetazoa|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Homo sapiens (Human)
Length = 1002
Score = 379 bits (933), Expect = e-104
Identities = 173/241 (71%), Positives = 204/241 (84%), Gaps = 1/241 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IG+EFMFIN LEQC WIRQ+ E P + + ++KR +LARL RST FE FL +KWSSEK
Sbjct: 217 HIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEK 276
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AG 360
RFGLEGCE+LIPA+K +ID S++ GV+ +IMGMPHRGRLNVLANV RK L Q+F QF +
Sbjct: 277 RFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSK 336
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
LEA D+GSGDVKYHLG Y R+NRVT++NI L++ ANPSHLEA DPVV GKT+AEQFY G
Sbjct: 337 LEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCG 396
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSR 720
D EGKKVMSILLHGDAAFAGQG+V+ET HLSDLP+YTTHGT+H+V NNQIGFTTDPR +R
Sbjct: 397 DTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMAR 456
Query: 721 S 723
S
Sbjct: 457 S 457
>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1054
Score = 362 bits (890), Expect = 5e-99
Identities = 166/230 (72%), Positives = 197/230 (85%), Gaps = 1/230 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IG+EFMFIN+++QC WIR ++E P + + KR +LARL RST FE+FLA+KWSSEK
Sbjct: 216 HIGVEFMFINNVDQCQWIRNKIETPGIMRFTDADKRTLLARLIRSTRFEDFLARKWSSEK 275
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AG 360
RFGLEGCE+LIPA+K +ID S+ GV+S+IMGMPHRGRLNVLANV RK L Q+F QF
Sbjct: 276 RFGLEGCEVLIPALKTIIDESSAAGVDSVIMGMPHRGRLNVLANVIRKDLDQIFCQFDPK 335
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
LEA D+GSGDVKYHLG Y ER+NR T+KNI L++ ANPSHLEAVDPVVQGKT+AEQFYRG
Sbjct: 336 LEAADEGSGDVKYHLGMYHERINRKTDKNITLSLVANPSHLEAVDPVVQGKTKAEQFYRG 395
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQI 690
D EGKKVMSIL+HGDAAFAGQGVV+ET HLS+LP+YTTHGTIH+V NNQ+
Sbjct: 396 DVEGKKVMSILIHGDAAFAGQGVVYETFHLSELPSYTTHGTIHVVVNNQV 445
>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG33791-PC, isoform C - Apis mellifera
Length = 980
Score = 300 bits (737), Expect = 2e-80
Identities = 137/241 (56%), Positives = 180/241 (74%), Gaps = 1/241 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
++G+E+ +I+ L +W+R + E P + AD ++ I + ++ FE FLA+K+ +EK
Sbjct: 181 HLGLEYTYIHDLVMLDWLRDKFEIPGAWDLPADHRKFIWMNIMKAVTFEGFLARKFPTEK 240
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFGLEGCE IP+M Q ++ S + GVES+++GM HRGRLN L NVC KPLHQL TQF +
Sbjct: 241 RFGLEGCESFIPSMNQCLETSAEHGVESVVIGMAHRGRLNTLINVCMKPLHQLLTQFHSI 300
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
E GSGDVKYHLGT+ ER+ + K IR+A+ ANPSHLEA+DPVV G+ RAEQ + D
Sbjct: 301 ALEGFGSGDVKYHLGTHAERMLERSQKQIRVAMMANPSHLEAIDPVVVGRVRAEQVEKND 360
Query: 544 NE-GKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSR 720
E GKK ++ L+HGDAAF+GQG+V+ETMHL++LP YTT G IHIV NNQIGFTTDPR+SR
Sbjct: 361 AEFGKKSVAFLVHGDAAFSGQGIVYETMHLTNLPNYTTGGVIHIVINNQIGFTTDPRYSR 420
Query: 721 S 723
S
Sbjct: 421 S 421
>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza
sativa (Rice)
Length = 1016
Score = 296 bits (726), Expect = 4e-79
Identities = 144/246 (58%), Positives = 184/246 (74%), Gaps = 7/246 (2%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
IG E+M I E+CNW+R R+E N + + D+++++L RL ST FE+FLA+KW++ KR
Sbjct: 197 IGYEYMHIPDREKCNWLRDRIETVNAREYSYDRRQVMLDRLMWSTQFESFLAQKWTTAKR 256
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG-- 360
FGLEG E LIP MK++ D + LGVESI++GMPHRGRLNVL NV RKPL Q+F++F+G
Sbjct: 257 FGLEGAETLIPGMKEMFDRAADLGVESIVIGMPHRGRLNVLGNVVRKPLRQIFSEFSGGT 316
Query: 361 LEAED-----DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAE 525
AE+ G+GDVKYHLGT +R R K+I L++ ANPSHLEAVDPVV GKTRA+
Sbjct: 317 KPAEEGEGLYTGTGDVKYHLGTSYDRPTR-GGKHIHLSLVANPSHLEAVDPVVAGKTRAK 375
Query: 526 QFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTD 705
Q+Y D + K + +LLHGD +F+GQGVV+ET+HLS LP YTT GTIHIV NNQ+ FTTD
Sbjct: 376 QYYSNDLDRTKNLGVLLHGDGSFSGQGVVYETLHLSALPNYTTGGTIHIVVNNQVAFTTD 435
Query: 706 PRHSRS 723
PR RS
Sbjct: 436 PRAGRS 441
>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
CaKGD1 2-oxoglutarate dehydrogenase; n=4;
Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida
albicans CaKGD1 2-oxoglutarate dehydrogenase -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 997
Score = 289 bits (709), Expect = 5e-77
Identities = 139/239 (58%), Positives = 179/239 (74%), Gaps = 1/239 (0%)
Frame = +1
Query: 10 GIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRF 189
G+E++ I S EQC+W+R+R+E P K + D+KR IL R+ S FE+FLA K+ ++KRF
Sbjct: 198 GVEYIHIPSKEQCDWLRERIEIPEPYKYSPDEKRQILDRVIWSCSFESFLASKFPNDKRF 257
Query: 190 GLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEA 369
GLEG E ++P MK +ID S + GVE I++GMPHRGRLN+L+NV RKP +F++F G
Sbjct: 258 GLEGAESVVPGMKAMIDTSVEFGVEDIVIGMPHRGRLNMLSNVVRKPNESIFSEFTGSRE 317
Query: 370 EDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD-N 546
D+GSGDVKYHLG R + K++ L++ ANPSHLE+ D VV GKTRA Q Y+ D
Sbjct: 318 FDEGSGDVKYHLGMNYAR-PTTSGKHVNLSLVANPSHLESEDGVVLGKTRAIQQYKNDIG 376
Query: 547 EGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
E KK MSILLHGDAAF+GQGVV+ETM L++LP Y+T GTIHI+ NNQIGFTTDPR +RS
Sbjct: 377 EYKKAMSILLHGDAAFSGQGVVYETMGLANLPDYSTGGTIHIIVNNQIGFTTDPRFARS 435
>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 1012
Score = 285 bits (698), Expect = 1e-75
Identities = 129/240 (53%), Positives = 175/240 (72%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
++G+E+++I+ W+R + E P ++ AD ++ I + ++ FENFLAKK+ +EK
Sbjct: 220 HLGLEYIYIHDSTVLEWLRYKFEIPGAWELAADHRKWIWVNIMKAVTFENFLAKKYGTEK 279
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFGLEGCE I +M Q ++ S++ GVE++ +GM HRGRLN L NVC KPLHQL TQF +
Sbjct: 280 RFGLEGCESFIASMAQCLETSSEQGVETVAIGMAHRGRLNTLVNVCSKPLHQLLTQFKPI 339
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
E GSGDVKYHLGT ER+ + K + ++V ANPSHLE+VD V G+ RAEQ +GD
Sbjct: 340 SLEGLGSGDVKYHLGTCAERVLERSGKKMHVSVTANPSHLESVDSVTVGRVRAEQVEKGD 399
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
+G+K ++IL+HGDAA++GQG+ +ETMHL+ LP YTT G IH V NNQIGFTTDPR+SRS
Sbjct: 400 IKGQKSLAILVHGDAAYSGQGICYETMHLTKLPDYTTGGVIHSVINNQIGFTTDPRYSRS 459
>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1013
Score = 280 bits (687), Expect = 2e-74
Identities = 135/244 (55%), Positives = 178/244 (72%), Gaps = 4/244 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IGIE+M I E C+WIR + E ++ +K IL RL+ + FE FL K+ + +
Sbjct: 207 DIGIEYMHIQDREMCDWIRDKFETSQPVEIPDKEKIKILERLSWADQFEGFLGLKYRATR 266
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG- 360
RFGL+GCE LIP MK +ID +T+ GVESI++GMPHRGRLNVLANV RKPL +F +F G
Sbjct: 267 RFGLDGCESLIPGMKAMIDTATEDGVESIVLGMPHRGRLNVLANVVRKPLPAIFNEFNGG 326
Query: 361 ---LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
+E E +GDVKYHLGT +R+ + K + L++ ANPSHLEAV+P+V+GK RA+Q
Sbjct: 327 VISIEGEYSATGDVKYHLGTSYDRVTS-SGKKVHLSLVANPSHLEAVNPLVEGKVRAKQH 385
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
Y D E KK M++ LHGDA+ AGQGVV+ET+HLS+L Y+T GT+HIV NNQIGFTT+P+
Sbjct: 386 YSKDTEQKKSMAVQLHGDASVAGQGVVYETLHLSNLDNYSTGGTVHIVVNNQIGFTTNPK 445
Query: 712 HSRS 723
+SRS
Sbjct: 446 YSRS 449
>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 1014
Score = 272 bits (666), Expect = 8e-72
Identities = 131/241 (54%), Positives = 174/241 (72%), Gaps = 3/241 (1%)
Frame = +1
Query: 10 GIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRF 189
G+++ I S ++C+W+R+R+E P + DQKR IL RLT +T FE+FL+ K+ ++KRF
Sbjct: 213 GVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRF 272
Query: 190 GLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEA 369
GLEG E ++P +K ++D S +LGVE I++GM HRGRLNVL+NV RKP +F++F G A
Sbjct: 273 GLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSA 332
Query: 370 EDD--GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
DD GSGDVKYHLG +R + K + L++ ANPSHLE+ DPVV G+TRA + D
Sbjct: 333 RDDIEGSGDVKYHLGMNYQR-PTTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKND 391
Query: 544 -NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSR 720
E K + +LLHGDAAFAGQGVV+ETM LP Y+T GTIH++ NNQIGFTTDPR +R
Sbjct: 392 LKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFAR 451
Query: 721 S 723
S
Sbjct: 452 S 452
>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Cystobacterineae|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Myxococcus xanthus (strain
DK 1622)
Length = 963
Score = 238 bits (583), Expect = 9e-62
Identities = 121/244 (49%), Positives = 161/244 (65%), Gaps = 3/244 (1%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRSTGFENFLAKKWSS 177
D IG+E+M + E+ W+ RME N T + D+ R IL +L+ + GFE+FL K+
Sbjct: 178 DTIGVEYMHMLDSERRRWLMHRMESNENRTDFSPDECRHILTKLSYAEGFEHFLHTKYVG 237
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
KRF L+G E LIP + + +V+T +G+ I++GM HRGRLNVL N+ K Q+F++F
Sbjct: 238 AKRFSLDGGEALIPMLDALGEVATGMGLREIVIGMAHRGRLNVLTNILGKQPDQIFSEFD 297
Query: 358 GLEAEDD--GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
G D G GDVKYH+G + R K + L++ NPSHLEAVDPVV+G+ RA+Q
Sbjct: 298 GPRNPQDYLGRGDVKYHMGFSSDHTTRQGRK-LHLSLAFNPSHLEAVDPVVEGRVRAKQD 356
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
GD E VM +L+HGDAAF GQGVV ET++LS L YTT GT+H+V NNQ+GFTTDP
Sbjct: 357 RGGDTERTSVMPLLIHGDAAFIGQGVVAETLNLSGLKGYTTGGTVHVVINNQVGFTTDPH 416
Query: 712 HSRS 723
SRS
Sbjct: 417 DSRS 420
>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Geobacter sulfurreducens
Length = 894
Score = 237 bits (579), Expect = 3e-61
Identities = 120/242 (49%), Positives = 162/242 (66%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
++G+EFM I + W+ +RMEP N ++ DQK IL +L ++ FE FL +K+ +
Sbjct: 132 SVGVEFMHIQDPAERTWLIERMEPVRNRPPVSLDQKLRILEKLREASLFEEFLHRKFLGQ 191
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA- 357
KRF LEG E LIPA+ V++ + +LGV+ +++GM HRGRLNVLA + KP+ +F +FA
Sbjct: 192 KRFSLEGGEALIPALDAVVERAARLGVDDLVLGMAHRGRLNVLATIIGKPVENIFAEFAD 251
Query: 358 GLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+E G GDVKYH G +R +I L + NPSHLEAV+PVV+GK RA Q R
Sbjct: 252 NVELAFVGDGDVKYHKGFSSDR-RFADGSSIHLTLAFNPSHLEAVNPVVEGKCRARQDAR 310
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
G ++V+ +L+HGDAAFAGQGVV ET++LS L Y T GT+HIV NNQIGFTT P +
Sbjct: 311 GPGGDRRVLPVLIHGDAAFAGQGVVAETLNLSQLEGYRTGGTLHIVINNQIGFTTVPADA 370
Query: 718 RS 723
RS
Sbjct: 371 RS 372
>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative; n=9; Plasmodium|Rep:
2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative - Plasmodium vivax
Length = 1059
Score = 229 bits (559), Expect = 7e-59
Identities = 111/243 (45%), Positives = 155/243 (63%), Gaps = 4/243 (1%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
IG E+M I N+I +R+E + + KR IL R+ FEN++A K+++ KR
Sbjct: 218 IGFEYMHITDESVVNYIVKRIERDRKFQYDRKTKRKILENTARAFIFENYMAAKFATTKR 277
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
FG++GCE LI MK +I + + ES++M M HRGRLNVL NV KPL + +F G
Sbjct: 278 FGVDGCETLITGMKALISRAAMVHTESVLMSMSHRGRLNVLFNVLHKPLENMMCEFRGKT 337
Query: 367 AEDDG----SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
D +GDVKYHLG I+ + +N+ I + + N SHLE+VDP++ G+ RA+Q+Y
Sbjct: 338 GFTDNIWGNTGDVKYHLGVEIDHFDEESNRYIHMGIVDNSSHLESVDPILMGQARAQQYY 397
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRH 714
D E +KV+ I +HGDA+ AGQG+ +ET+ +S LP+Y GTIHIV NNQIGFTT P
Sbjct: 398 CNDKEKEKVLPITIHGDASIAGQGIAYETLQMSKLPSYNVGGTIHIVVNNQIGFTTYPVD 457
Query: 715 SRS 723
+RS
Sbjct: 458 ARS 460
>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Corynebacterium glutamicum (Brevibacterium
flavum)
Length = 1257
Score = 227 bits (554), Expect = 3e-58
Identities = 116/242 (47%), Positives = 157/242 (64%), Gaps = 3/242 (1%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
+G E+ I ++ W++ R+E A+QK IL +L + FENFL K+ +KR
Sbjct: 487 VGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQK-YILQKLNAAEAFENFLQTKYVGQKR 545
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL- 363
F LEG E LIP M ID + G++ +++GMPHRGRLNVL N+ KPL +F +F G
Sbjct: 546 FSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNEFEGQM 605
Query: 364 -EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
+ + GSGDVKYHLG+ + L + I++++ ANPSHLEAV+PV++G RA+Q Y
Sbjct: 606 EQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAKQDYLD 665
Query: 541 DN-EGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
+GK V+ +LLHGDAAFAG G+V ET++L+ L Y GTIHIV NNQIGFTT P S
Sbjct: 666 KGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTTTPDSS 725
Query: 718 RS 723
RS
Sbjct: 726 RS 727
>UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: Oxoglutarate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 384
Score = 226 bits (553), Expect = 4e-58
Identities = 120/243 (49%), Positives = 156/243 (64%), Gaps = 4/243 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNAD-QKRLILARLTRSTGFENFLAKKWSSE 180
N+G+E+M + W++ RME N + QKR IL+R+ ++ FE FL K+ +
Sbjct: 140 NVGVEYMHVQDHAAREWLQVRMEATNNNPAFTNAQKRRILSRIHKAELFEKFLHTKYVGQ 199
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG E LI A+ +I+ + +GVE ++GM HRGRL+VLAN RKP LF QF+
Sbjct: 200 KRFSLEGGETLIAALDAMIEHAPDVGVEEFVLGMAHRGRLSVLANTLRKPFDVLFEQFSE 259
Query: 361 --LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
+ G GDVKYHLG Y L T K I + + ANPSHLE V+PVV+GKTRA Q
Sbjct: 260 NYIPHTVAGDGDVKYHLG-YEAALETTTGKTIEVRLAANPSHLEIVNPVVEGKTRARQRI 318
Query: 535 RGD-NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
RGD E ++V +L+HGDAAFAGQGVV ET++ S L Y+T GT+H V N QIGFTT P
Sbjct: 319 RGDATERRRVCPLLIHGDAAFAGQGVVAETLNFSQLTGYSTGGTLHFVINKQIGFTTLPS 378
Query: 712 HSR 720
+R
Sbjct: 379 DAR 381
>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
decarboxylase - Lentisphaera araneosa HTCC2155
Length = 913
Score = 225 bits (550), Expect = 9e-58
Identities = 111/243 (45%), Positives = 157/243 (64%), Gaps = 3/243 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+IG+E+ + S E W+ ++ME N N QK IL +LT+ GFE FL K+ +
Sbjct: 135 SIGVEYRYSQSSEMRQWLHEKMESNANKPNFNKTQKMNILKKLTQGVGFEKFLGVKYVGQ 194
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG E IPAM ++ + ++LGV+ +MGM HRGRLNVLAN+ K LF +F G
Sbjct: 195 KRFSLEGLEAFIPAMTELFNQGSRLGVQEFVMGMAHRGRLNVLANLFEKEYKALFQEFEG 254
Query: 361 LEAEDD--GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
DD G GDVKYH+G + + N + L++ ANPSHLEAV+PVV G+ RA+
Sbjct: 255 HALPDDVGGDGDVKYHMGHSADVVTEDGNP-LHLSLAANPSHLEAVNPVVLGRVRAKIEE 313
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRH 714
+N+ K++ IL+HGDAA +GQG+++E ++++L Y T GT+H+V NNQ+GFT + R
Sbjct: 314 LYENDPNKIVPILVHGDAAISGQGIIYEICNMANLDGYGTGGTVHVVLNNQVGFTANYRE 373
Query: 715 SRS 723
SRS
Sbjct: 374 SRS 376
>UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 component;
n=1; Gluconobacter oxydans|Rep: 2-Oxoglutarate
dehydrogenase E1 component - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 885
Score = 224 bits (548), Expect = 2e-57
Identities = 115/232 (49%), Positives = 154/232 (66%), Gaps = 3/232 (1%)
Frame = +1
Query: 16 EFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGL 195
EFM + Q W R+E P + D KR++LA LTR+ GFE F K++ +RFGL
Sbjct: 117 EFMHLQDPAQRQWWIDRLENP-APGPSLDPKRILLA-LTRAEGFEQFCQKRFMGMRRFGL 174
Query: 196 EGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAED 375
EG E +I A++ +ID + + + S+ +GMPHRGRLNV+AN+ RKP +F++FAG +
Sbjct: 175 EGGESVIVALRTLIDAAAQDDIRSVSLGMPHRGRLNVMANILRKPFAAIFSEFAGASFKP 234
Query: 376 D---GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDN 546
D GSGDVKYHLGT + +R+++ NPSHLEAVDPVV G+ RA+Q D
Sbjct: 235 DTIEGSGDVKYHLGTATTLEH--AGHTVRISLLPNPSHLEAVDPVVLGRVRADQDREKDR 292
Query: 547 EGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
E + + IL+HGDAAFAGQGVV+ET+ LS L Y T GT+H++ NNQIGFTT
Sbjct: 293 ERQHHLGILVHGDAAFAGQGVVYETLSLSKLEGYRTGGTVHVIINNQIGFTT 344
>UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E1
component, sucA; n=1; Candidatus Protochlamydia
amoebophila UWE25|Rep: Probable 2-oxoglutarate
dehydrogenase E1 component, sucA - Protochlamydia
amoebophila (strain UWE25)
Length = 890
Score = 223 bits (546), Expect = 3e-57
Identities = 115/245 (46%), Positives = 159/245 (64%), Gaps = 4/245 (1%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPNVTK-MNADQKRLILARLTRSTGFENFLAKKWSS 177
D IG E+ +N + WI+ +E + + +QK+ +LA L+RS FE FL K+
Sbjct: 120 DRIGFEYKHLNDKKMEVWIQDFIEQQFFKQTLTKEQKQHVLACLSRSELFETFLHTKYIG 179
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+KRF LEG E LIP + +I+ + GV+ ++GM HRGRLNVLAN+ K L +F++F
Sbjct: 180 QKRFSLEGAETLIPMLDLLIEAGAEQGVQEFLVGMAHRGRLNVLANILNKSLDTIFSEFG 239
Query: 358 G--LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
+ +G GDVKYH G E++ K+I++++ NPSHLE+V+ VV+GKTRA+QF
Sbjct: 240 EEYIPTSLEGMGDVKYHKGYTGEKIKTRLGKSIKISLSPNPSHLESVNAVVEGKTRAKQF 299
Query: 532 YRGDNEG-KKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDP 708
G + KK++ IL+HGDAA +GQGVV+ET+ LS L Y T GTIH V NNQIGFTT P
Sbjct: 300 LAGGEKARKKIIPILIHGDAAVSGQGVVYETLQLSQLKGYETGGTIHFVINNQIGFTTIP 359
Query: 709 RHSRS 723
R RS
Sbjct: 360 RDLRS 364
>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_5,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1002
Score = 221 bits (541), Expect = 1e-56
Identities = 112/244 (45%), Positives = 154/244 (63%), Gaps = 5/244 (2%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
I E+M I S E+ NWIR+++E + +QK RL + F FL KK+++ KR
Sbjct: 198 ISYEYMHIQSTEERNWIREQIEKFEEFLPSKEQKLKTFERLGQEHAFSTFLQKKFNTSKR 257
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
FG+EGC+ +I ++ ++D + GVE I+ GM HRGRLN L NV +K ++ +F L+
Sbjct: 258 FGIEGCDSMISGLQSMVDSAASAGVEYIVFGMAHRGRLNTLYNVFQKSPEEIMVEFQDLK 317
Query: 367 A---ED--DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
ED SGDVKYHLG+ + + + K +RL + NPSHLE VDP V GK RA Q
Sbjct: 318 GIYNEDIWGNSGDVKYHLGS-VHNV-KFGEKKLRLEMLPNPSHLETVDPCVYGKVRAIQD 375
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
Y D G K +L+HGDAA AGQG+VFE++ ++DL Y + G IH+V+NNQIGFTT P+
Sbjct: 376 YHKDRNGDKAFGVLIHGDAAVAGQGIVFESLQMADLEGYKSGGIIHVVSNNQIGFTTVPK 435
Query: 712 HSRS 723
SRS
Sbjct: 436 DSRS 439
>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component; n=4;
Bacteroidetes|Rep: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 946
Score = 221 bits (539), Expect = 2e-56
Identities = 113/242 (46%), Positives = 154/242 (63%), Gaps = 3/242 (1%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVT-KMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
IG E+M+I E+ W+R ++E ++ + D+K+ IL++L + FENFL K+ +K
Sbjct: 168 IGFEYMYIRKPEKLAWLRNKIEKESLAHNLTLDEKKRILSKLNEAVVFENFLHTKYVGQK 227
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RF LEG E IPA+ ++I S +LGVE +++GM HRGRLNVLAN+ K Q+F +F G
Sbjct: 228 RFSLEGGETTIPALDKMITASAELGVEEVVIGMAHRGRLNVLANIMGKTYEQIFNEFEGN 287
Query: 364 EAED--DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
D G GDVKYH+G Y + + I L + NPSHLEAVDPVV G RA+
Sbjct: 288 IKPDMTMGDGDVKYHMG-YSSEVVTPKGQKINLKLMPNPSHLEAVDPVVLGFVRAKGDRL 346
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
+ KKV+ +L+HGDAA A QG+V+E + +S L Y T GTIH V NNQ+GFTTD +
Sbjct: 347 YGYDYKKVLPVLIHGDAAVAAQGIVYEIVQMSKLAGYQTGGTIHFVINNQVGFTTDFEDA 406
Query: 718 RS 723
RS
Sbjct: 407 RS 408
>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family
protein - Tetrahymena thermophila SB210
Length = 992
Score = 217 bits (530), Expect = 2e-55
Identities = 103/245 (42%), Positives = 159/245 (64%), Gaps = 6/245 (2%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
IG E+ I ++++ W+++R+E + N ++ L RL R+ F FL ++S+ KR
Sbjct: 184 IGFEYYHIENVDEKLWLQKRIEDIGLKPQNNVDRKKTLERLLRNEQFNLFLKNRFSTSKR 243
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL- 363
FG+EGC+ I + ++D + + GV+S+I+GMPHRGRLN LA V K Q+F +F +
Sbjct: 244 FGIEGCDSFISGLGALVDHACENGVQSLILGMPHRGRLNTLACVFNKNPEQIFAEFQEIR 303
Query: 364 -----EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQ 528
+AE SGDVKYHLG E++N + K I++++ NPSHLE V+PV G RA Q
Sbjct: 304 DKSLDDAEWGNSGDVKYHLGCTTEKVNP-SGKKIKMSILPNPSHLETVNPVTMGCVRAVQ 362
Query: 529 FYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDP 708
++GD+ G K + +L+HGD++F+GQGVV+E++ + +L Y+ G +HI+ NNQIGFTT P
Sbjct: 363 DFKGDSTGLKTLGVLVHGDSSFSGQGVVYESLQMQELVGYSPRGIVHIIVNNQIGFTTTP 422
Query: 709 RHSRS 723
R+
Sbjct: 423 AEYRT 427
>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 1304
Score = 216 bits (527), Expect = 5e-55
Identities = 116/242 (47%), Positives = 154/242 (63%), Gaps = 3/242 (1%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
+GIE+M I EQ W+++R+E P + D +R IL L R+ FE FL K+ +KR
Sbjct: 514 VGIEYMHIQDPEQRAWVQKRIERPYEAP-SPDAQRHILGTLIRAEAFEEFLQTKFMGQKR 572
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG-- 360
F LEG E LIP + ++ S + G+ + +GM HRGRLNVLAN+ K Q+F +F G
Sbjct: 573 FSLEGGESLIPLLDHILADSARTGIHEVAIGMAHRGRLNVLANIAGKSYAQIFDEFEGNY 632
Query: 361 LEAEDDGSGDVKYHLGTY-IERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+ GSGDVKYHLGT+ + L+ + +A ANPSHLEA D V++G RA+Q +
Sbjct: 633 MPNSVQGSGDVKYHLGTWGVYSLDDGLATKVYMA--ANPSHLEAADGVLEGIVRAKQEHL 690
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
GD + ++ IL+HGDAAF GQGVV ET++LS L Y T GTIHI+ NNQIGFTT P
Sbjct: 691 GDPD-LPIIPILIHGDAAFIGQGVVQETLNLSQLEGYKTGGTIHIIVNNQIGFTTGPTQG 749
Query: 718 RS 723
RS
Sbjct: 750 RS 751
>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
subunit - Solibacter usitatus (strain Ellin6076)
Length = 1220
Score = 215 bits (525), Expect = 9e-55
Identities = 113/243 (46%), Positives = 157/243 (64%), Gaps = 4/243 (1%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
IG E+M I EQ W++QRMEP N ++ + + L + FE+FL ++ +K
Sbjct: 429 IGCEYMNIQVPEQKRWLQQRMEPEANNWLLDRETRLRTLHSVIAGEEFEHFLHSRFVGQK 488
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RF LEG E + ++++++ + V I++GM HRGRLN+LAN K + Q+F++F G
Sbjct: 489 RFALEGGETALAILEEILERAAGRNVHEIVVGMAHRGRLNILANTVGKDVKQIFSEFEGE 548
Query: 364 --EAEDDGSGDVKYHLGTYIERLNRVTN-KNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
GSGDVKYHLG + R +N + I ++V NPSHLEAVDPVV+G R +Q
Sbjct: 549 IDPGSTQGSGDVKYHLGA--TGMRRTSNGREIVVSVSPNPSHLEAVDPVVEGIVRPKQDR 606
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRH 714
GD E ++V+ +L+HGDAAFAGQGVV ET++LS L Y+T GTIH++ NNQIGFTT P
Sbjct: 607 LGDTERERVIPVLIHGDAAFAGQGVVTETLNLSQLEGYSTGGTIHLIINNQIGFTTLPDE 666
Query: 715 SRS 723
SRS
Sbjct: 667 SRS 669
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 215 bits (525), Expect = 9e-55
Identities = 117/252 (46%), Positives = 160/252 (63%), Gaps = 13/252 (5%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNV-TKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
IG+EFM I+ + WI++R+E P+ + K+ IL++L + GFE F+ K+ K
Sbjct: 210 IGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKLIEAEGFEQFIDVKYKGTK 269
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AG 360
RFGL+G E LIPA++Q++ ++G++ +++GM HRGRLNVL+ V KP +F +F G
Sbjct: 270 RFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVLSQVMGKPHRAIFHEFKGG 329
Query: 361 LEAEDD--GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
DD GSGDVKYHLG +R + L++ ANPSHLE V+PVV GK RA+Q
Sbjct: 330 SYTPDDVEGSGDVKYHLGASSDR--EFDGNKVHLSLTANPSHLEIVNPVVMGKARAKQDL 387
Query: 535 -----RGD----NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQ 687
R D +E KV+ +LLHGDAAFAGQGVV E + LS L + GT+H + NNQ
Sbjct: 388 LVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGLKGHRVAGTLHFIINNQ 447
Query: 688 IGFTTDPRHSRS 723
IGFTT+P SRS
Sbjct: 448 IGFTTNPAFSRS 459
>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=16; cellular organisms|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Robiginitalea biformata
HTCC2501
Length = 940
Score = 214 bits (522), Expect = 2e-54
Identities = 108/238 (45%), Positives = 154/238 (64%), Gaps = 3/238 (1%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRSTGFENFLAKKWSS 177
D IG+E+M+I S E+ WI+Q + N + ++K+ IL +L + FE FL K+
Sbjct: 152 DAIGVEYMYIRSPERVEWIQQWLNVNDNHPNFSPERKKYILRKLNEAVSFEGFLHTKYVG 211
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+KRF LEG E LIPA+ +++ + +LGV+ +MGM HRGRLNVL N+ KP +F++F
Sbjct: 212 QKRFSLEGNESLIPAVDAIVERAAELGVQQFVMGMAHRGRLNVLTNIFGKPATDIFSEFE 271
Query: 358 GLEAEDD-GSGDVKYHLG-TYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
G + E + GDVKYHLG T + + N + +I + + NPSHLE V VV+G TRA+Q
Sbjct: 272 GKDYEQEIFDGDVKYHLGWTSMRKTN--SGDSINMNIAPNPSHLETVGAVVEGITRAKQD 329
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTD 705
+ KV+ I++HGDAA AGQG+ +E + ++ L Y T GTIHIV NNQIGFTT+
Sbjct: 330 RHFPEDFSKVLPIVVHGDAAIAGQGIAYEVVQMAGLDGYGTAGTIHIVVNNQIGFTTN 387
>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
component - Leptospira interrogans
Length = 920
Score = 213 bits (521), Expect = 3e-54
Identities = 110/243 (45%), Positives = 153/243 (62%), Gaps = 2/243 (0%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPN-VTKMNADQKRLILARLTRSTGFENFLAKKWSS 177
+ IG E ++ + E+ W++++ME P + + K + +L ++ FE FLAKK+
Sbjct: 148 NTIGAEHFYLVNDEEREWLQKKMESPEFLAPLPRGIKLRLFEKLFQADYFETFLAKKYVG 207
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+KRF LEG E IP + +++ + ++ +++GM HRGRLNVL N+ KP +F +F
Sbjct: 208 KKRFSLEGGESFIPLLDTIVEEAGYHQMDGLVIGMAHRGRLNVLVNIIEKPASLIFAEFE 267
Query: 358 GLEAEDDGS-GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
+D+ S DVKYHLG R+ + K ++L++ NPSHLE VDPVV G RA Q
Sbjct: 268 EKTDKDNLSYADVKYHLGYSNSRMT-TSGKEVKLSLAFNPSHLECVDPVVTGSVRARQTL 326
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRH 714
GD + K M IL+HGDAAFAGQGVV ET++L +L YTT GT HIV NNQIGFTT P
Sbjct: 327 IGDKDRSKYMPILIHGDAAFAGQGVVAETLNLMNLEGYTTGGTFHIVVNNQIGFTTLPDE 386
Query: 715 SRS 723
SRS
Sbjct: 387 SRS 389
>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
dehydrogenase E1 - Blastopirellula marina DSM 3645
Length = 929
Score = 213 bits (519), Expect = 5e-54
Identities = 106/242 (43%), Positives = 153/242 (63%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNV-TKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
++GI+ I+ W+ + +E + + + D +R IL RLT + FE F+ KK+
Sbjct: 157 DVGIQLQHIDDHVVRRWLIEEVEGDDRDSSLGRDTQRRILQRLTEAMVFEEFVRKKYLGA 216
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
K F LEG E LIP + I + G+ +++ MPHRGRL+VLANV R+P ++F+QF
Sbjct: 217 KTFSLEGSETLIPLLDLAIHGFAEQGISELVLAMPHRGRLSVLANVIRQPPREIFSQFED 276
Query: 361 LEAEDD-GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+ + G GDVKYH+G + + + K + +++C NPSHLE VDPV G+ RA+Q R
Sbjct: 277 ADPKRHIGGGDVKYHMGASGDYV-AASGKKVHVSLCFNPSHLEYVDPVALGRMRAKQDRR 335
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
GD E + +L+HGDAAFAG+GVV ET++LS L Y T GT+H++ NNQ+GFTT P S
Sbjct: 336 GDTERQMGAVVLIHGDAAFAGEGVVQETLNLSQLHGYRTGGTLHVIVNNQLGFTTQPHDS 395
Query: 718 RS 723
RS
Sbjct: 396 RS 397
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Salinibacter ruber (strain DSM 13855)
Length = 1243
Score = 211 bits (515), Expect = 1e-53
Identities = 112/250 (44%), Positives = 156/250 (62%), Gaps = 11/250 (4%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+G FM I+ E+ WI+ R+EP N + +++ I+ +L + FE FL K+ K
Sbjct: 461 VGTAFMHISDPEEKTWIQNRIEPMRNAGSPSEEERHRIVQKLNAAEAFERFLHTKYIGHK 520
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG- 360
RF LEG E +IP + ++ + GVE ++MGM HRGRLNVLAN+ KP ++F++F G
Sbjct: 521 RFSLEGSETMIPLIDTLLSDAADEGVEEVVMGMAHRGRLNVLANIIGKPYEEIFSKFEGN 580
Query: 361 LEAE-DDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
++ GSGDVKYHLG + + I + + +NPSHLEAV+PVV+G +RA+Q
Sbjct: 581 IDPNTTQGSGDVKYHLGAEGD-VTSPDGNEISVTLASNPSHLEAVNPVVEGMSRAKQNLL 639
Query: 538 GDNEGK--------KVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIG 693
D + VM +L+HGDA FAGQGVV ET++LS L YTT GT+H+V NNQIG
Sbjct: 640 RDEHPEAAEDDYHDAVMPLLIHGDAGFAGQGVVAETLNLSKLRGYTTGGTVHLVINNQIG 699
Query: 694 FTTDPRHSRS 723
FTT P +RS
Sbjct: 700 FTTPPGDARS 709
>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
component family protein; n=1; Tetrahymena thermophila
SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
family protein - Tetrahymena thermophila SB210
Length = 1054
Score = 210 bits (514), Expect = 2e-53
Identities = 111/247 (44%), Positives = 152/247 (61%), Gaps = 6/247 (2%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+ +G ++M IN+ + +WIRQR+E K +Q RL R F FL K+S+
Sbjct: 242 NKVGYQYMHINNKTERDWIRQRIENAEQFKPTKEQLVRTADRLCRDYCFTEFLNNKFSTS 301
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-- 354
KRFG EGC+ I + ++D + +E+I++GMPHRGRLN L +V +KP + +F
Sbjct: 302 KRFGSEGCDSFISGLGALVDHAADKKIENIVIGMPHRGRLNTLYSVLKKPAVNILAEFQD 361
Query: 355 ---AGLEAEDDG-SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRA 522
A + E+ G SGDVKYHLGT ++ + +RL++ ANPSHLEAV+PVV GK R
Sbjct: 362 INVAKFDEENWGNSGDVKYHLGTTKDKA--YGDHTVRLSIMANPSHLEAVNPVVYGKLRC 419
Query: 523 EQFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
Q D G K IL+HGDAAF+GQG+V+E++ + DL Y G IHIV NNQIGFTT
Sbjct: 420 VQDATQDTNGDKSFGILIHGDAAFSGQGIVYESIQMHDLKDYNNGGIIHIVVNNQIGFTT 479
Query: 703 DPRHSRS 723
P SR+
Sbjct: 480 YPGDSRT 486
>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Azotobacter vinelandii
Length = 943
Score = 209 bits (510), Expect = 6e-53
Identities = 111/241 (46%), Positives = 145/241 (60%), Gaps = 2/241 (0%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKM-NADQKRLILARLTRSTGFENFLAKKWSSEK 183
IG EF I EQ NW QR+E + + + K +L RL+ + G E +L K+ K
Sbjct: 172 IGAEFTHIVDSEQRNWFAQRLESVRGRPVYSKEAKSHLLERLSAAEGLEKYLGTKYPGTK 231
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFGLEG E L+P + ++I S G + +++GM HRGRLN+L N K LF +F G
Sbjct: 232 RFGLEGGESLVPVVDEIIQRSGSYGTKEVVIGMAHRGRLNLLVNALGKNPRDLFDEFEGK 291
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
+ GSGDVKYH G + + + LA+ NPSHLE V PVV+G RA Q R D
Sbjct: 292 HLVELGSGDVKYHQGFSSNVMT--SGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRRVD 349
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPRHSR 720
G+KV+ I +HGD+AFAGQGVV ET +S + Y T GTIHIV NNQ+GFTT +P +R
Sbjct: 350 ATGEKVVPISIHGDSAFAGQGVVMETFQMSQIRGYKTGGTIHIVVNNQVGFTTSNPVDTR 409
Query: 721 S 723
S
Sbjct: 410 S 410
>UniRef50_UPI0000DAE34D Cluster: hypothetical protein
Rgryl_01000074; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000074 - Rickettsiella
grylli
Length = 929
Score = 206 bits (504), Expect = 3e-52
Identities = 107/241 (44%), Positives = 154/241 (63%), Gaps = 1/241 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+IG E+ I Q W+++R+E +A K+ IL L R+ G E FL K+ ++
Sbjct: 163 SIGFEYEHIACHAQRTWLQERIESVTGKPDFSAKVKKNILKGLIRADGLEKFLGNKFVAQ 222
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG + LIP ++ +I +++ VE I++GM HRGRLNVL N+ K QLF +F G
Sbjct: 223 KRFSLEGGDSLIPLLEALITDASRAEVEEIVIGMAHRGRLNVLINILGKSPAQLFEEFEG 282
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
+++ SGDVKYH G + + + + +A+ NPSHLE V+PVV+G R+ Q R
Sbjct: 283 KMIQENRSGDVKYHKGFAADL--KTDHGVMHVAMAFNPSHLEIVNPVVEGSVRSRQERRQ 340
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSR 720
+ ++V+ +L+HGDAAF+GQGVV E LS AY T GT+HIV NNQ+GFTTDP+++R
Sbjct: 341 EGGQQQVLPLLIHGDAAFSGQGVVMENFELSQTQAYGTGGTLHIVLNNQLGFTTDPQNAR 400
Query: 721 S 723
S
Sbjct: 401 S 401
>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
Rhodopirellula baltica
Length = 969
Score = 206 bits (504), Expect = 3e-52
Identities = 105/242 (43%), Positives = 154/242 (63%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+IG +FM I++ +W+++RME N ++ + +R I RL +T FE F+ +K+
Sbjct: 196 SIGAQFMHIDNRNIRDWLQRRMETTENRLDLSHEVQRRIYTRLADATIFEEFVRRKFVGA 255
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
K F LEG E LIP + ++ + + V+ ++M M HRGRLNV+AN+ +K +F F
Sbjct: 256 KTFSLEGAESLIPLIDLALEKAGQHQVKEVVMAMAHRGRLNVMANILKKRAMNIFWSFDD 315
Query: 361 LEAE-DDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
E G GDV+YHLG Y + + +++C NPSHLE V+ V G+TR +Q R
Sbjct: 316 PTPELSRGGGDVRYHLG-YSSDWKTASGDRLHISLCFNPSHLEYVNTVALGRTRCKQDNR 374
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
GD + + VM+IL+HGDAAFAG+GVV ET++LS+L Y T GT+H+V NNQ+GFTT+P
Sbjct: 375 GDVDRQDVMTILIHGDAAFAGEGVVQETLNLSELKGYRTGGTLHVVINNQVGFTTEPDEG 434
Query: 718 RS 723
RS
Sbjct: 435 RS 436
>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=12; root|Rep: 2-oxoglutarate dehydrogenase,
E1 component - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 963
Score = 206 bits (503), Expect = 4e-52
Identities = 116/244 (47%), Positives = 149/244 (61%), Gaps = 5/244 (2%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEP----PNVTKMNADQKRLILARLTRSTGFENFLAKKWS 174
IG E+M+ Q W +Q++E PN+TK ++K IL RLT + G E FL K+
Sbjct: 181 IGAEYMYATDQNQKRWWQQKLESIRSKPNLTK---EKKLHILDRLTAAEGLERFLHTKYV 237
Query: 175 SEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF 354
+KRF LEG E I +M ++I GV+ I++GM HRGRLNVL N K LF +F
Sbjct: 238 GQKRFSLEGGESFIASMDELIQQGGIKGVQEIVIGMAHRGRLNVLVNSLGKVPADLFAEF 297
Query: 355 AGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
ED SGDVKYH G + + L++ NPSHLE V+PVV+G RA
Sbjct: 298 DHTAPEDLPSGDVKYHQGFSSDVTT--PGGPVHLSLAFNPSHLEIVNPVVEGSVRARMDR 355
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPR 711
R D +G +V+ +L+HGDAAFAGQGVV ET+ L++ Y T GT+HIV NNQIGFTT DPR
Sbjct: 356 RADPKGLQVLPVLVHGDAAFAGQGVVMETLALAETRGYFTGGTVHIVINNQIGFTTSDPR 415
Query: 712 HSRS 723
SRS
Sbjct: 416 DSRS 419
>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Anaeromyxobacter sp. Fw109-5
Length = 940
Score = 206 bits (502), Expect = 6e-52
Identities = 101/240 (42%), Positives = 146/240 (60%), Gaps = 1/240 (0%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPP-NVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+G+E ++ + W+ QRME N + + KR +L ++ + E +L K+ K
Sbjct: 158 LGVELAHMHDADLRGWLEQRMERTRNRVSLEPEVKRRLLEKVVEAETLEQYLGTKFLGAK 217
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RF +EG E L+P + +D + GV ++++GM HRGRLNVLANV KPL +F +F
Sbjct: 218 RFSVEGAEGLLPLFELAVDRAIGHGVRNVVIGMAHRGRLNVLANVVGKPLRDIFAEFRDA 277
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
+ G GDVKYHLG +R + L++ NPSHLE +D VVQG+ RA+Q D
Sbjct: 278 AIINAGGGDVKYHLGYSSDR-ESAEGVLVHLSLAFNPSHLEWIDTVVQGRVRAKQDRYRD 336
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
+ + + IL+HGDAAFA QGVV E++ +S+L Y GTIH++ NNQ+GFTT PR +RS
Sbjct: 337 TDRHRSLPILVHGDAAFAAQGVVAESLQMSELEGYAVGGTIHVIVNNQVGFTTSPRDARS 396
>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
fastidiosa
Length = 967
Score = 205 bits (500), Expect = 1e-51
Identities = 111/242 (45%), Positives = 144/242 (59%), Gaps = 5/242 (2%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPN-VTKMNADQKRLILARLTRSTGFENFLAKKWSS 177
D IG EFM I+ EQ WI +R+E NA ++ IL RLT + G E +L K+
Sbjct: 186 DTIGTEFMHISEFEQRQWIYRRLENVGGKIASNATNRKRILERLTAAEGLERYLHTKYVG 245
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+KRF LEG + LIP M ++ + V+ I++GM HRGRLNVL N K +LF +F
Sbjct: 246 QKRFSLEGSDTLIPLMDTLVRQAGNNDVKDIVVGMAHRGRLNVLVNTLGKNPRKLFDEFE 305
Query: 358 GL--EAEDDGS--GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAE 525
G A D + GDVKYH+G + + K + LA+ NPSHLE VDPVV G R+
Sbjct: 306 GKFEHAHHDRAHTGDVKYHMG-FSADIAVGDGKQVHLALAFNPSHLEIVDPVVAGSVRSR 364
Query: 526 QFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTD 705
Q GD E K V+ IL+HGDAAFAGQGVV E + +S + GT+H++ NNQIGFTT
Sbjct: 365 QERFGDTERKTVLPILIHGDAAFAGQGVVMELLQMSQARGFAVGGTLHVIINNQIGFTTS 424
Query: 706 PR 711
R
Sbjct: 425 AR 426
>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Haemophilus influenzae
Length = 935
Score = 204 bits (499), Expect = 1e-51
Identities = 108/242 (44%), Positives = 150/242 (61%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTGFENFLAKKWSSE 180
+IG+EFM + +EQ W++ +ME + ++R+ L LT + G E +L K+
Sbjct: 169 SIGLEFMHVQDMEQKMWLQSKMESLLDKPLFTSEERVNFLRELTAADGLERYLGAKFPGA 228
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG + IP MK++I S++ GV ++MGM HRGRLN+L NV K LF +FAG
Sbjct: 229 KRFSLEGSDAFIPLMKEIIRHSSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAG 288
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
+ + +GDVKYH G + V +K + L + NPSHLE V PVV G R+ Q
Sbjct: 289 KHSSER-TGDVKYHQGFSSDFA--VDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMN 345
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPRHS 717
D E KV++I +HGD+A AGQGVV ET+++S+ Y+ GTI IV NNQIGFTT +P +
Sbjct: 346 DTEHSKVLAITVHGDSAVAGQGVVQETLNMSNTRGYSVGGTIRIVINNQIGFTTSNPNDT 405
Query: 718 RS 723
RS
Sbjct: 406 RS 407
>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
component; n=7; Bacteria|Rep: 2-oxoglutarate
dehydrogenase complex, E1 component - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 942
Score = 204 bits (498), Expect = 2e-51
Identities = 110/242 (45%), Positives = 146/242 (60%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVT-KMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+IG E+M I+ Q WI+ R+E T + +A+ K+ IL R T + E FL K+ +
Sbjct: 164 SIGSEYMHISDTGQKRWIQSRLESVRGTPRFSAEMKKRILERTTAAETLEKFLHTKYVGQ 223
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG E I AM +++ V LG + I++GM HRGRLNVL N K LF +F G
Sbjct: 224 KRFSLEGGESTIVAMDEIVRVGGSLGAQEIVIGMAHRGRLNVLVNTLGKSPSMLFAEFEG 283
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
A D +GDVKYHLG + ++ + L + NPSHLE ++PVV+G A Q R
Sbjct: 284 KAAADLTAGDVKYHLGFSSDVMS--PGGPVHLTLSFNPSHLEIINPVVEGSVYARQLRRK 341
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPRHS 717
D +V+++L+HGDAA AGQGV E ++ S Y T GT+HIV NNQIGFTT DPR
Sbjct: 342 DEAKSQVIAVLIHGDAAVAGQGVNQEMLNFSQTRGYGTGGTVHIVVNNQIGFTTSDPRDY 401
Query: 718 RS 723
RS
Sbjct: 402 RS 403
>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
component - Rickettsia felis (Rickettsia azadi)
Length = 977
Score = 204 bits (498), Expect = 2e-51
Identities = 111/243 (45%), Positives = 152/243 (62%), Gaps = 3/243 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IG+EF I ++E+ NW+ ++E VT +++ K+ IL L GFE +L K+ K
Sbjct: 209 SIGVEFEQIENVEEKNWLYNKLES-EVT-FSSEDKKTILNDLVEVEGFEQYLHTKFPGAK 266
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-AG 360
RF +EG + I AM + ID+S GVE I++GM HRGRLN L V KP + F +G
Sbjct: 267 RFSVEGGDASIVAMSKAIDLSMNQGVEEIVIGMAHRGRLNTLTKVVGKPYKAVIAGFISG 326
Query: 361 LEAEDD--GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
D+ SGDVKYHLG +R + NK I L++ NPSHLEAV+P+V GK RA+Q
Sbjct: 327 SVFPDELNVSGDVKYHLGYSSDRT--IDNKKIHLSLADNPSHLEAVNPIVAGKVRAKQDI 384
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRH 714
GD + KV +IL+HGDAAF GQGVV E++ +S L AY G +H V NNQ+GFT +
Sbjct: 385 LGDTKRSKVKAILVHGDAAFCGQGVVAESLSMSPLAAYDIGGILHFVINNQLGFTANAAD 444
Query: 715 SRS 723
+R+
Sbjct: 445 TRA 447
>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Francisella tularensis|Rep: 2-oxoglutarate
dehydrogenase E1 component - Francisella tularensis
subsp. tularensis (strain FSC 198)
Length = 941
Score = 203 bits (496), Expect = 3e-51
Identities = 106/234 (45%), Positives = 148/234 (63%), Gaps = 1/234 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
NIG E+ +I + E+ W++ R+E V + +D K+ IL +L + G E +LA ++ +K
Sbjct: 171 NIGYEYRYIGNKEEKLWLQDRIEDTAV--IPSDSKKWILQQLVAAEGLEKYLALRYVGQK 228
Query: 184 RFGLEGCEILIPAMKQVIDVS-TKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
RFGLEG E LIP+++ +++ + ++ I +GM HRGRLNVL NV K LF +F G
Sbjct: 229 RFGLEGGESLIPSLQHIVEKAVSRHSTRFIQLGMAHRGRLNVLVNVMGKNPKDLFEEFEG 288
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
++E SGDVKYH+G + K ++A+ NPSHLEAVDPVV+G +A Q
Sbjct: 289 KQSEKSLSGDVKYHMG--YSNYRSIDGKEAKIALAFNPSHLEAVDPVVEGAAKAIQDKLD 346
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
+ KV+ IL+HGD+AF GQGVV ET S AY T GTIH+V NNQ+GFTT
Sbjct: 347 GDVYSKVLPILIHGDSAFCGQGVVMETFGFSLTEAYGTGGTIHLVVNNQVGFTT 400
>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr13 scaffold_17, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 973
Score = 203 bits (496), Expect = 3e-51
Identities = 115/240 (47%), Positives = 147/240 (61%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IG E+M I ++CNW+R ++E P + N ++ +IL RL ST FENFLA KW++ K
Sbjct: 205 SIGYEYMHIADRDKCNWLRDKIETPTPRQYNQQRREVILDRLIWSTQFENFLATKWTAAK 264
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFGLE G E++I GM V P+ + GL
Sbjct: 265 RFGLE-------------------GGETLIPGMKEMFDRAADLGVESIPVDDV-----GL 300
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
G+GDVKYHLGT +R R + I L++ ANPSHLEAVDPVV GKTRA+Q+Y D
Sbjct: 301 YT---GTGDVKYHLGTSYDRPTR-GGRRIHLSLVANPSHLEAVDPVVVGKTRAKQYYSND 356
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
+ K + +L+HGD +FAGQGVV+ET+HLS LP YTT GTIHIV NNQ+ FTTDPR RS
Sbjct: 357 LDRTKNIGVLIHGDGSFAGQGVVYETLHLSALPNYTTGGTIHIVVNNQVAFTTDPRSGRS 416
>UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;
n=4; Paramecium tetraurelia|Rep: 2-oxoglutarate
dehydrogenase, putative - Paramecium tetraurelia
Length = 964
Score = 200 bits (487), Expect = 4e-50
Identities = 106/243 (43%), Positives = 150/243 (61%), Gaps = 5/243 (2%)
Frame = +1
Query: 10 GIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRF 189
G+E++ + S EQ +W+ Q M+ K + + + RL R F FL ++++ KRF
Sbjct: 164 GVEYIHMVSTEQKHWVEQEMDRIAQWKPSKETQTATWQRLARVDLFNEFLKNRFTTSKRF 223
Query: 190 GLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG--- 360
G+EG + LI ++ ++D + VE II+GM HRGRL+ LANV +KPL +F +F
Sbjct: 224 GIEGTDTLIVGLEALVDQCAQNKVEHIIVGMAHRGRLSTLANVFKKPLEIIFAEFQNKYS 283
Query: 361 --LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
+E GDVKYHLG ++ +IR+ + NPSHLEAV+PVVQGKTRA Q
Sbjct: 284 KEIEESWGNIGDVKYHLGVTRDQ-QFPDGHHIRMTMLPNPSHLEAVNPVVQGKTRALQDI 342
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRH 714
G+ + + I++HGDAA AGQGVV+E++ L +L Y+ G IH+V NNQIGFTT P
Sbjct: 343 CGNKQ--NCLGIIIHGDAAMAGQGVVYESLQLENLTGYSNEGVIHVVVNNQIGFTTTPID 400
Query: 715 SRS 723
SRS
Sbjct: 401 SRS 403
>UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus
oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus
oryzae
Length = 453
Score = 200 bits (487), Expect = 4e-50
Identities = 103/234 (44%), Positives = 147/234 (62%), Gaps = 1/234 (0%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
+GIE+M I++ EQ +WIR R+E + ++KR +L L R+T +E F+A K+ +EKR
Sbjct: 148 MGIEYMHISNQEQVDWIRARIEGAQRHRFTDEEKRRMLHGLVRATSWEKFVATKFPNEKR 207
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
FGL+G E IPA++ ID S + GV+ I MG+ HRGR+N+L N+ K +F F
Sbjct: 208 FGLDGVESYIPALETAIDRSAEHGVDKIEMGVAHRGRMNMLYNIVGKDGASMFRDFDPKG 267
Query: 367 AEDDG-SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
G GD+KYH G ER+ + K + + V PSHL++V+PV GKTR Q D
Sbjct: 268 TSSWGIPGDIKYHYGGSGERVT-PSGKKVYMNVLPQPSHLDSVNPVAMGKTRGIQDRLAD 326
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTD 705
E + M + +H DA+FA QG ++ET+ LS LP YTT GT+ ++ NNQ+GFTTD
Sbjct: 327 -ERESTMMLNVHTDASFAAQGTIYETLGLSGLPGYTTGGTLRVIVNNQVGFTTD 379
>UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=20; Bacillaceae|Rep: 2-oxoglutarate dehydrogenase E1
component - Bacillus anthracis
Length = 955
Score = 198 bits (483), Expect = 1e-49
Identities = 110/253 (43%), Positives = 156/253 (61%), Gaps = 13/253 (5%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTGFENFLAKKWSSE 180
++ EF I E+ W+ Q +E ++ + +++KR +L RLT GFE FL K + +
Sbjct: 155 SLAYEFSHIQDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQ 214
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF-- 354
KRF +EG ++L+P + +++ K GVE +++GM HRGRL+VLA+V KP +F +F
Sbjct: 215 KRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKH 274
Query: 355 ---AGLEAEDDGSGDVKYHLGTYIERLNRVTNKNI--RLAVCANPSHLEAVDPVVQGKTR 519
G A +GDVKYHLG R V+N+ + R+ + NPSHLE V+PVV+G R
Sbjct: 275 AKIEGAVANSGWTGDVKYHLG----REQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFAR 330
Query: 520 AEQFYR-----GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANN 684
A Q R + + K IL+HGDAAF GQG+V ET++LS L AY T GTIH++ANN
Sbjct: 331 AAQENRKKSGLPEQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANN 390
Query: 685 QIGFTTDPRHSRS 723
+GFTTD SRS
Sbjct: 391 AVGFTTDSYDSRS 403
>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=15; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Deinococcus radiodurans
Length = 956
Score = 197 bits (480), Expect = 3e-49
Identities = 110/247 (44%), Positives = 152/247 (61%), Gaps = 8/247 (3%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTK---MNADQKRLILARLTRSTGFENFLAKKWSS 177
IG E+ ++ + E+ W ++R+E ++ D++R ++ +L + G E +L ++
Sbjct: 158 IGFEYNYLPANERA-WFQERIEKGRGQGRYGLSQDERRRLMQKLNAAEGLELYLKNRYPG 216
Query: 178 EKRFGLEGCEILIPAMKQVID-VSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF 354
KRFGLEG E IP M ++I + GV+ +++GM HRGRLN L N+ KP LF +F
Sbjct: 217 VKRFGLEGGESFIPLMDRIIQQAGGRYGVKEVVVGMAHRGRLNTLVNIFGKPSGTLFDEF 276
Query: 355 AG---LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAE 525
G L + D +GDVKYH+G Y + R + LA+ NPSHLE V PVV G RA
Sbjct: 277 DGKKKLSDDPDIAGDVKYHMG-YSSDV-RTPGGPMHLAMAFNPSHLEIVSPVVHGSVRAR 334
Query: 526 QFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFT-T 702
Q RGD E K+V+ I +HGDAA +GQGVV ET++ S L +TT G I IV NNQIGFT +
Sbjct: 335 QDRRGDTERKQVLPITVHGDAAVSGQGVVMETLNFSRLRGFTTGGAIRIVINNQIGFTIS 394
Query: 703 DPRHSRS 723
DPR SRS
Sbjct: 395 DPRDSRS 401
>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase E1 component, putative - Leishmania major
Length = 979
Score = 194 bits (474), Expect = 1e-48
Identities = 102/248 (41%), Positives = 155/248 (62%), Gaps = 9/248 (3%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTK-----MNADQKRLILARLTRSTGFENFLAKKW 171
IG E + + + ++R ++E + M+ +++ I + + FE+F +K+
Sbjct: 187 IGFELVHLTDGDAKRFVRSQIELKDGCSALHRPMSREERLRIWDTVASAVFFEDFFKRKY 246
Query: 172 SSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQ 351
S++KRFG +G E ++ ++ +++ S++LGV++I +GM HRGRLNVL +V KP + +
Sbjct: 247 STQKRFGCDGAESMVAGLRALLEKSSELGVQAINLGMAHRGRLNVLCHVIGKPFEVILKE 306
Query: 352 FAGLEAED----DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTR 519
F G+ ++ DVKYHLG Y +L + K + + NPSHLEAV+P VQG TR
Sbjct: 307 FVGVTGQELHPFQIQSDVKYHLG-YRGQLKLNSGKVMETEMLFNPSHLEAVNPFVQGYTR 365
Query: 520 AEQFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFT 699
A Q G+ +KV+ I +HGDAAFAGQGV FETM +S++ T GT+H+V NNQIGFT
Sbjct: 366 AMQVSLGEKGREKVLPIEIHGDAAFAGQGVAFETMCISEVGEQDTGGTVHVVCNNQIGFT 425
Query: 700 TDPRHSRS 723
TDP+ SRS
Sbjct: 426 TDPKSSRS 433
>UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=8; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Geobacillus kaustophilus
Length = 950
Score = 194 bits (472), Expect = 2e-48
Identities = 110/260 (42%), Positives = 160/260 (61%), Gaps = 19/260 (7%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTGFENFLAKKWSS 177
D I EF +++LE+ NW+ Q++E A+++R+ +L RLT GFE F+ + +
Sbjct: 159 DKIAFEFSQVHNLEERNWLIQQIESGAYYPSLANKERVALLRRLTEVEGFEKFIHRTYVG 218
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+KRF +EG + ++P + +++ + + ++++ +GM HRGRLNVLA+V KP +F +F
Sbjct: 219 QKRFSIEGLDSMVPLLDELVRQAIEHEIDAVNIGMAHRGRLNVLAHVLGKPYEMIFAEFQ 278
Query: 358 GLEAED----DGS--------GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPV 501
E+++ +GS GDVKYHLG RL + +R+ + NPSHLE V+PV
Sbjct: 279 HAESKNFIPSEGSVAITYGWTGDVKYHLGA-ARRLRNQSAHTMRITLANNPSHLEVVNPV 337
Query: 502 VQGKTRAEQFYRGDNEGKKVMS------ILLHGDAAFAGQGVVFETMHLSDLPAYTTHGT 663
V G TRA Q R G V + IL+HGDAAF GQG+V ET++LS L YTT GT
Sbjct: 338 VLGYTRAAQEDR-TKPGVPVQNTDASFAILIHGDAAFPGQGIVAETLNLSQLRGYTTGGT 396
Query: 664 IHIVANNQIGFTTDPRHSRS 723
IHI+ANN IGFTT+ SRS
Sbjct: 397 IHIIANNMIGFTTESYDSRS 416
>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase
E1 component - Staphylococcus aureus
Length = 932
Score = 193 bits (470), Expect = 4e-48
Identities = 104/256 (40%), Positives = 156/256 (60%), Gaps = 17/256 (6%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
I E+ IN+ + W+++R+E P +N ++KR + +L GFE +L K + KR
Sbjct: 149 IAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKR 208
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
F +EG + L+P +++ I ++ K G+++I +GM HRGRLNVL +V KP + ++F +
Sbjct: 209 FSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTD 268
Query: 367 ----AEDDGS--------GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQG 510
+DGS GDVKYHLG + T + R+A+ NPSHLE V PVV+G
Sbjct: 269 PMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQ--RIALANNPSHLEIVAPVVEG 326
Query: 511 KTRAEQ--FYRG---DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIV 675
+TRA Q R + K M I++HGDAA+ GQG+ FETM+L +L Y+T G++HI+
Sbjct: 327 RTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHII 386
Query: 676 ANNQIGFTTDPRHSRS 723
NN+IGFTT+P +RS
Sbjct: 387 TNNRIGFTTEPIDARS 402
>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Proteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 940
Score = 191 bits (466), Expect = 1e-47
Identities = 106/242 (43%), Positives = 144/242 (59%), Gaps = 3/242 (1%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRME-PPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
IG E+M I + WI+ +E + + + +R IL RLT + G E +L + +K
Sbjct: 167 IGAEYMHITETAEKRWIQSYLEGAQDDPGPSVELQRHILERLTAAEGLERYLHTNYVGQK 226
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RF LEG + LIP + +I + GV I++GM HRGRLNVL N K LF +F G
Sbjct: 227 RFSLEGGDSLIPLLDNLILYAGSKGVGEIVIGMAHRGRLNVLVNTLGKLPRDLFMEFEGQ 286
Query: 364 -EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
E ++ SGDVKYHLG + + + + NPSHLE +DPVV+G RA Q R
Sbjct: 287 HETDNKRSGDVKYHLGFSAD--GDTPGGPVHITLAFNPSHLEIIDPVVEGSVRARQQRRK 344
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPRHS 717
D G +V+ +L+HGD+AFAGQGVV ET ++S + T GT+HIV NNQIGFTT +P +
Sbjct: 345 DWLGDEVIPVLIHGDSAFAGQGVVMETFNMSQSRGFFTGGTLHIVINNQIGFTTSNPLDT 404
Query: 718 RS 723
RS
Sbjct: 405 RS 406
>UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1
subunit; n=3; cellular organisms|Rep: Predicted
2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus
tauri
Length = 1210
Score = 190 bits (464), Expect = 2e-47
Identities = 104/247 (42%), Positives = 145/247 (58%), Gaps = 8/247 (3%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
+ +E + S ++ W+R + E + + +R LARL R+ ENFLA+++ S KR
Sbjct: 185 MSVECNHLTSQDRKRWLRMQFES-GPERPSEKTRRKTLARLLRADMLENFLAERFPSAKR 243
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
FGLEG E LIP ++ ++ + + VESI++GMPHRGRLNVL NV KPL + + +
Sbjct: 244 FGLEGAESLIPGLQAFVERAAERRVESIVLGMPHRGRLNVLHNVFGKPLGAISAEIVD-D 302
Query: 367 AEDDGSGDVKYHLGTYIE---RLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
GDV+YHLG + + + + + NPSHLE V+ VV G RA+QF R
Sbjct: 303 RSSFLVGDVRYHLGARARVDVEIEEGEKRPVTMTLVPNPSHLEMVNAVVSGVVRAKQFRR 362
Query: 538 -----GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
G V+ +LLHGDA+F G G E M L DLP Y+T GT+H++ NNQIGFTT
Sbjct: 363 DPEAQGAGARAHVLPLLLHGDASFCGLGQTAEVMTLQDLPDYSTGGTVHVIVNNQIGFTT 422
Query: 703 DPRHSRS 723
PR +RS
Sbjct: 423 VPRRARS 429
>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
decarboxylase - Plesiocystis pacifica SIR-1
Length = 927
Score = 190 bits (463), Expect = 3e-47
Identities = 99/242 (40%), Positives = 148/242 (61%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
++G+E+ + Q W++QRME N D++ +L+ L ++FL K+
Sbjct: 145 HVGVEYWHLYDPAQRAWLQQRMEGCQNEVVPPQDEQVRLLSSLINVDTVDHFLHSKFLGA 204
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF + G E LIP + +I+ + + + +I GM HRGRLNVL N+ K ++F +F+
Sbjct: 205 KRFSISGAESLIPLLDCLIEGAAEHDIGEVIFGMAHRGRLNVLMNILGKAPKEVFEEFSN 264
Query: 361 LEAEDD-GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+AE G+GDVKYHLG Y T+++I LA+ NPSHLEA+ PV+QG+ RA+Q
Sbjct: 265 TDAESYIGAGDVKYHLG-YHRYHKTSTDRDIYLALAFNPSHLEAITPVIQGRVRAKQDAN 323
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
+ +++ +HGDAAF+GQGVV ET++++ L Y G I +V NNQIGFTTDP +
Sbjct: 324 PERGHAASLAVTMHGDAAFSGQGVVSETLNMAALEGYEAGGVIRVVINNQIGFTTDPTDA 383
Query: 718 RS 723
RS
Sbjct: 384 RS 385
>UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Neorickettsia sennetsu str.
Miyayama|Rep: 2-oxoglutarate dehydrogenase, E1 component
- Neorickettsia sennetsu (strain Miyayama)
Length = 905
Score = 189 bits (461), Expect = 5e-47
Identities = 101/244 (41%), Positives = 141/244 (57%), Gaps = 5/244 (2%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMN--ADQKRLILARLTRSTGFENFLAKKWSS 177
+IG++FM ++ + W+ +R+E ++ K +L L R G E F+ K+ +
Sbjct: 142 HIGVQFMHLSDNSEVTWLEERLEGRPFCRIGFGTSHKLALLDVLIRVNGLEEFVNTKFRA 201
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
KRF +EGC+ + A++ +I+V+ G +I+GM HRGRLN L N K LF F
Sbjct: 202 VKRFSVEGCDTALVALESIIEVAANAGCTDVIVGMSHRGRLNSLVNTFGKKYRALFHGFE 261
Query: 358 G---LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQ 528
G E GDVKYH G ER ++ K I + NPSHL++VDPV+ G RA +
Sbjct: 262 GKSPFPEECKIHGDVKYHYGFSCERKTFLSEKTIFARLLHNPSHLDSVDPVLVGAARAAK 321
Query: 529 FYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDP 708
+ G V +LLHGDAAF+GQGVV+ETM L +LP Y + G IHI+ NNQIGFTT P
Sbjct: 322 -----DSGAVVFPVLLHGDAAFSGQGVVYETMLLEELPNYESGGVIHIILNNQIGFTTSP 376
Query: 709 RHSR 720
+ R
Sbjct: 377 QDVR 380
>UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Acidobacteria bacterium Ellin345|Rep:
2-oxoglutarate dehydrogenase, E1 component -
Acidobacteria bacterium (strain Ellin345)
Length = 820
Score = 188 bits (458), Expect = 1e-46
Identities = 94/240 (39%), Positives = 145/240 (60%), Gaps = 1/240 (0%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
IG+EFM I E+ WI ++ E D +R +L L R+ FE L ++ KR
Sbjct: 62 IGVEFMHIADPERRRWIAEKFEGEPGP---VDHRR-VLDALVRADMFEQTLQSRYIGTKR 117
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
+ LEG LIP + ++++ + + G E +M M HRGRLNV+ NV +P ++F F ++
Sbjct: 118 YSLEGNTSLIPLLHEILNAAAEHGAEQAVMAMSHRGRLNVIVNVVNRPAAEIFAGFEDVD 177
Query: 367 AEDD-GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
G GDVKYH+G+ + + + + + + +NPSHLEAV+PV G+ +A+Q G+
Sbjct: 178 PRSVLGGGDVKYHIGSTGD-YHAANGQTVHIHLASNPSHLEAVNPVAAGRVKAKQQRIGE 236
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
KV+ +++HGD AFAGQG+V ET++L LP + GT+H++ANN IGFT +PR + S
Sbjct: 237 GGIPKVVPLIMHGDTAFAGQGIVAETLNLEHLPGFDIGGTVHVIANNLIGFTANPREAYS 296
>UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Oxoglutarate
dehydrogenase - Dictyostelium discoideum AX4
Length = 900
Score = 188 bits (458), Expect = 1e-46
Identities = 93/244 (38%), Positives = 144/244 (59%), Gaps = 3/244 (1%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+++ +F I S+E+ W+ ++ E + +K IL L +S F+ F+ KK+ +
Sbjct: 107 NDVTAQFDHIESIEEKAWLYEKFEQLQHQNPSKSEKINILKNLIKSEIFDQFMQKKFPTF 166
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KR+GLEG E ++ + + S K ++++++GMPHRGRLN+L +C P F + G
Sbjct: 167 KRYGLEGNESMMVSCDSIFRESAKNQLKNVVIGMPHRGRLNLLVQMCNYPAKDFFWKVKG 226
Query: 361 LEAEDDGS---GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
+G GDV H+ + +++ +++ NPSHLEAVDPV GKTRA+QF
Sbjct: 227 NSEFSEGILGVGDVTSHIAVSTDLQFNNNKESVHVSLIHNPSHLEAVDPVAAGKTRAKQF 286
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
Y + G + + ++LHGDAA AGQGVV ET+ LS L + G +H++ NNQIGFTT P
Sbjct: 287 YEKNEGGSESLCLMLHGDAAVAGQGVVTETLQLSQLSGFNIGGCVHVIVNNQIGFTTVPT 346
Query: 712 HSRS 723
+ RS
Sbjct: 347 NGRS 350
>UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=7; Chlamydiaceae|Rep: 2-oxoglutarate dehydrogenase E1
component - Chlamydophila abortus
Length = 908
Score = 188 bits (457), Expect = 2e-46
Identities = 94/201 (46%), Positives = 125/201 (62%), Gaps = 2/201 (0%)
Frame = +1
Query: 127 LTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNV 306
+ ++T FE FL K++ +KRF LEGCE L+ ++ ++ + S I+GM HRGRLNV
Sbjct: 175 ICKATFFEEFLQVKFTGQKRFSLEGCESLVSMLEHLVRYGVTQNITSYILGMAHRGRLNV 234
Query: 307 LANVCRKPLHQLFTQFAGLEAED--DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSH 480
L NV KP Q+F +F D GDVKYH G Y+ R + + + NPSH
Sbjct: 235 LTNVLGKPYSQVFMEFEDNPQFRGLDTVGDVKYHKG-YVSRSFGQHGEEVTFVMLPNPSH 293
Query: 481 LEAVDPVVQGKTRAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHG 660
LEAVDPVV+G A Q + ++IL+HGDAAF+GQGVV+ET+ LS +P Y+T G
Sbjct: 294 LEAVDPVVEGVVAALQHQVDAGKEHSCLAILVHGDAAFSGQGVVYETLQLSQIPGYSTGG 353
Query: 661 TIHIVANNQIGFTTDPRHSRS 723
T+HI+ NN IGFT PR SRS
Sbjct: 354 TLHIIVNNHIGFTAQPRESRS 374
>UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Enterobacteriaceae|Rep: 2-oxoglutarate
dehydrogenase E1 component - Buchnera aphidicola subsp.
Schizaphis graminum
Length = 923
Score = 184 bits (449), Expect = 1e-45
Identities = 106/242 (43%), Positives = 144/242 (59%), Gaps = 2/242 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTGFENFLAKKWSSE 180
+IG E+M+I + + WI + +E + ++++ L + FE +L KK+S
Sbjct: 158 SIGFEYMYIENSFEKKWITKHIELFFKENLFIKKEKIRFLKEILYGETFEKYLGKKFSGT 217
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG E LI + ++I S K V II+GM HRGRLNVL NV K LF +F+G
Sbjct: 218 KRFSLEGGETLISILHEIIRYSKKNDVSEIILGMAHRGRLNVLVNVLNKNPQVLFNEFSG 277
Query: 361 LEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRG 540
+ + SGDVKYH+G + N K I L + NPSHLE V+PVV G RA
Sbjct: 278 INIPKEYSGDVKYHMGGITKIKN--DKKKIYLKLAYNPSHLEIVNPVVLGIARASINQLK 335
Query: 541 DNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPRHS 717
+E K +SI +HGDA+ GQGV+ ET+++S AY GTIHIV NNQIGFTT +P++
Sbjct: 336 ISE-NKFLSINIHGDASIIGQGVIQETLNMSQTEAYKIGGTIHIVINNQIGFTTSNPKNL 394
Query: 718 RS 723
RS
Sbjct: 395 RS 396
>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=5; Enterobacteriaceae|Rep: 2-oxoglutarate
dehydrogenase E1 component - Escherichia coli (strain
UTI89 / UPEC)
Length = 939
Score = 183 bits (446), Expect = 3e-45
Identities = 96/229 (41%), Positives = 133/229 (58%)
Frame = +1
Query: 16 EFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGL 195
E + + E+ NW+ R+E N + +A +L + E +L ++ +KRF L
Sbjct: 171 ELAHLENREEINWLLSRIESSNAPQADAQTCIARFEKLMAAETLERYLHTRYVGQKRFSL 230
Query: 196 EGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAED 375
EG E IPA+ + GVE +++GM HRGRLNVL N+ K QLF +F G +
Sbjct: 231 EGGESAIPALDTLTKRLRAQGVEEMVIGMAHRGRLNVLVNLLNKDPAQLFAEFEGKQTIG 290
Query: 376 DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGK 555
GSGDVKYH+G Y L ++ +A+ NPSHLE V+PVV G+ RA Q RG++
Sbjct: 291 SGSGDVKYHMG-YSSNLETPAG-SLHVALAYNPSHLEIVNPVVLGQVRARQERRGEDGQA 348
Query: 556 KVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
KV+ +L+HGD+A G GV T +LS Y T GT+H+V NNQIGFTT
Sbjct: 349 KVVGVLIHGDSALGGLGVNQTTFNLSQTQGYGTGGTLHLVINNQIGFTT 397
>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Orientia tsutsugamushi Boryong|Rep:
2-oxoglutarate dehydrogenase, E1 component - Orientia
tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 963
Score = 183 bits (446), Expect = 3e-45
Identities = 96/236 (40%), Positives = 142/236 (60%), Gaps = 2/236 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
NI +EF + ++ +W+ ++E ++ + + L+L L TGFE FL K+ K
Sbjct: 182 NIAVEFNHLTDRDEIDWLYDQLEQVSLNLNDNIDRELLLKNLISITGFEEFLHTKFVGAK 241
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG- 360
RF ++G E I A+ I+ + ++ +++GM HRGRL LA V +KP + + ++F
Sbjct: 242 RFSIQGAEASIAAVIDAIEQAIDYCIKEVVIGMAHRGRLVTLAEVAKKPHYAIISEFMNE 301
Query: 361 LEAEDDG-SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+ D SGDVKYH+G + N NI++++ NPSHLEAV+ VV GK RA+Q
Sbjct: 302 VHINDKNISGDVKYHMG--YSGVYTGKNNNIKISLTPNPSHLEAVNSVVAGKVRAKQDDL 359
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTD 705
D E K+VM IL+HGDAAF+GQGVV E++ LS L Y G +H + NNQIGFT +
Sbjct: 360 EDIERKQVMGILIHGDAAFSGQGVVAESLLLSALKPYAAGGILHYIINNQIGFTAN 415
>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component
, putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
dehydrogenase E1 component , putative - Babesia bovis
Length = 891
Score = 182 bits (444), Expect = 6e-45
Identities = 100/239 (41%), Positives = 144/239 (60%), Gaps = 4/239 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+ +EF+ + EQ +I +R+E P + + + + R+ FE F K + + K
Sbjct: 109 DFAVEFIHLPEEEQRFFI-ERIERPGAMDFSKEDRLNFFRSIARAVTFERFCTKAFPTVK 167
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFG +G E I A+ + ++S GV+S+IMGM HRGRLN+L NV +PL ++F +F G
Sbjct: 168 RFGADGIESSILAVDVLSEMSMAFGVDSLIMGMSHRGRLNMLVNVLNRPLEEMFAEFRGK 227
Query: 364 E-AEDDGS---GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
+GS GDVKYH G +R N+ + + NPSHL+ V PVV GK RA Q
Sbjct: 228 NWYATEGSEYCGDVKYHFGYSSKR------GNLHVDMLNNPSHLQFVHPVVAGKARARQV 281
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDP 708
+ E +V+ ++LHGDAAF+G+GV +ET+ +S +P YT GTI+IV NNQIGFTT P
Sbjct: 282 I-SNLESTRVLPVVLHGDAAFSGEGVTYETVQMSRIPEYTVGGTINIVVNNQIGFTTYP 339
>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase subunit, putative - Trypanosoma brucei
Length = 1008
Score = 182 bits (442), Expect = 1e-44
Identities = 96/241 (39%), Positives = 142/241 (58%), Gaps = 2/241 (0%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
+IG EF+ + +W + + ++ +++ IL + +S GFE F+ K+ ++
Sbjct: 191 SIGFEFLLTEGDDVRHWFHKEILK-TFEPLSKEERIHILDDVVKSCGFETFIQLKYGTQL 249
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFGL+G E L+PA+ ++ ++ LGV S + GMPHRGRLN+LANV KPL + +F G
Sbjct: 250 RFGLDGAEALVPAVIALMQEASDLGVTSFVQGMPHRGRLNLLANVKVKPLTDILAEFEGK 309
Query: 364 EAEDDGS--GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+ + GD KYHLG ++ K I + NPSHLEA++P+V GK RA
Sbjct: 310 THRNAIARLGDNKYHLGAD-RQIELRNGKVINFDLLCNPSHLEAMNPLVLGKARARMVVE 368
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHS 717
D+E + + I+ HGDAA +G G+ ETM L DL Y GT+HI+ NNQ+GFTTD +
Sbjct: 369 KDSECVRTLPIIAHGDAAISGLGMGHETMGLWDLDNYRVGGTVHIITNNQVGFTTDSVDA 428
Query: 718 R 720
R
Sbjct: 429 R 429
>UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1
component - Anaplasma marginale (strain St. Maries)
Length = 930
Score = 179 bits (436), Expect = 6e-44
Identities = 95/242 (39%), Positives = 151/242 (62%), Gaps = 4/242 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNA-DQKRLILARLTRSTGFENFLAKKWSSE 180
+IG EFM I S E+ +W+R ++E N +++ A ++KR L L + FE FL ++
Sbjct: 164 SIGYEFMHIPSSEERDWLRDKIE--NTSRVIAPERKRETLRCLQETELFEQFLHVRYPGY 221
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF +EG ++L+P ++++I ++ + +++G+ HRGRL+VL V RKP + +F+G
Sbjct: 222 KRFSVEGGDVLVPLLERIIALAPGFNCKEVVLGLSHRGRLSVLTRVMRKPYAAVLYEFSG 281
Query: 361 LEAEDDG---SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
A +G SGDVKYHLG + ++ + + L++ N S LE+V+PVV G+ +A
Sbjct: 282 GMAYPEGLSLSGDVKYHLGYSTD--TKIGGETVHLSLAYNSSSLESVNPVVMGRVKA--- 336
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
+ D + + V+ IL+HG+AAF GQGVV E LS + Y+ G +H+V NNQ+GFT DP
Sbjct: 337 -KSDEKRQPVLGILVHGNAAFIGQGVVSEGFTLSGVAGYSPGGIVHVVVNNQVGFTADPE 395
Query: 712 HS 717
S
Sbjct: 396 SS 397
>UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E1 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 933
Score = 179 bits (435), Expect = 7e-44
Identities = 89/236 (37%), Positives = 141/236 (59%), Gaps = 1/236 (0%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRL-ILARLTRSTGFENFLAKKWSSEK 183
IG E+M I++ ++ W+++ +E K+ + +K+ IL L +ST +ENF+ KK+ K
Sbjct: 163 IGFEYMHISNTKEKLWLQKNIESKKFEKLFSKRKKKNILKNLIKSTVYENFINKKFPGTK 222
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RF LEGC+ L+P +K++I+ + I +GM HRGRLNV+ N+ + +F
Sbjct: 223 RFSLEGCDSLLPMIKEIINFCLNKKITKIFLGMAHRGRLNVMHNILKHNTLNMFLNIQDK 282
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGD 543
+GDVKYH+G +++ V N+ + + + NPSHLE + PVV G + F
Sbjct: 283 LCHSHRTGDVKYHIG--LKKKIFVNNQEVEINLLNNPSHLEIITPVVIGCCKF--FIENK 338
Query: 544 NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
+ +++HGDAAF GQGV+ ET+++S +PAY G+IHIV NN+I FTT +
Sbjct: 339 KTIISPLPVIIHGDAAFTGQGVIQETLNMSQVPAYNVFGSIHIVINNKIAFTTSKK 394
>UniRef50_A3IFN6 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Bacillus sp. B14905|Rep: Alpha-ketoglutarate
decarboxylase - Bacillus sp. B14905
Length = 670
Score = 177 bits (431), Expect = 2e-43
Identities = 102/259 (39%), Positives = 150/259 (57%), Gaps = 18/259 (6%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPNVTK-MNADQKRLILARLTRSTGFENFLAKKWSS 177
+ + E+ + + E+ NWI+ ++E + + +++D+K+ +L RLTR FE F+ K +
Sbjct: 165 NKVAFEYEHVVATEERNWIQAQIESGSFQQALSSDEKKALLDRLTRVENFEKFIHKTFVG 224
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+KRF EG + I ++I + L VE + +GM HRGRLNVL ++ KP +F+ FA
Sbjct: 225 QKRFSGEGLDTQIVLFDEIIKTAEALSVEKVRIGMAHRGRLNVLTHILNKPYDMMFSDFA 284
Query: 358 ------------GLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPV 501
LE +GDVKYH+G NR + N++LA NPSHLE +PV
Sbjct: 285 HVSNDLFMPENGRLEITKGWTGDVKYHMGA---SYNRDSGMNVKLAY--NPSHLEVGNPV 339
Query: 502 VQGKTRAEQF-----YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTI 666
V G TRA Q + ++ K + IL+HGDAAF GQG+V E ++ + +TT GTI
Sbjct: 340 VLGATRATQDDTSKPGQAIHDRTKGLGILVHGDAAFPGQGIVTEVLNFAKTEGFTTGGTI 399
Query: 667 HIVANNQIGFTTDPRHSRS 723
HI+ANN IGFTT+ SRS
Sbjct: 400 HIIANNMIGFTTEQYDSRS 418
>UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 974
Score = 177 bits (430), Expect = 3e-43
Identities = 95/251 (37%), Positives = 146/251 (58%), Gaps = 12/251 (4%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
+ +E +++LE+ W+ R E +A+++R + + S F++FLA K+++ KR
Sbjct: 131 LSVETSQLSTLEEREWLADRFEELKKKSFSAEERRRLAKVMLESQEFDHFLAAKFATVKR 190
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
+G EG E ++ ++ S+ GV I++GMPHRGRLN+L + + P +F + GL
Sbjct: 191 YGGEGAESMMGFFYELFHQSSHSGVTDIVIGMPHRGRLNLLTGLLKFPPELMFRKMRGLS 250
Query: 367 AEDDGS---GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
D S GDV HL + +E L+ + + + + NPSHLEA+DPV QGKTRA Q R
Sbjct: 251 EFPDSSPAIGDVLSHLTSSVE-LDFGAGRPLHVTMLPNPSHLEAIDPVAQGKTRARQQLR 309
Query: 538 --GD-------NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQI 690
GD G +V+ + +HGD +F GQG+V ET+ LS LP Y G+IH++ NNQ+
Sbjct: 310 KEGDYSPEDAAQPGDQVICLQVHGDGSFTGQGIVAETLTLSKLPHYRVGGSIHLIVNNQV 369
Query: 691 GFTTDPRHSRS 723
G+TT RS
Sbjct: 370 GYTTPSERGRS 380
>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
dehydrogenase E1 component - Blochmannia floridanus
Length = 970
Score = 174 bits (424), Expect = 2e-42
Identities = 102/249 (40%), Positives = 140/249 (56%), Gaps = 17/249 (6%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVT---KMNADQKRLILARLTRSTGFENFLAKKWSS 177
IGIE+M I + Q WI+ E + + ++R L L S E +L K+
Sbjct: 177 IGIEYMHILDINQILWIQDYFESHTIEISDHFSVKEQRQFLNELIASEELERYLGIKFPG 236
Query: 178 EKRFGLEGCEILIPAMKQVIDVST-KLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQF 354
KRF LEG ++LIP +K+ I S ++ I +GMPHRGRLN L NV K LF +F
Sbjct: 237 SKRFSLEGGDVLIPMLKEAIRYSVLNHNIQEIFLGMPHRGRLNTLINVLGKNPQDLFNEF 296
Query: 355 AGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRA--EQ 528
G + SGDVKYH G Y E + ++ + +++ NPSHLE + PV+ G RA EQ
Sbjct: 297 YGTNQKYTNSGDVKYHQGLYSEVT--INSQIVHISLLFNPSHLEIITPVMMGAARARIEQ 354
Query: 529 FYRGD------NEGKK-----VMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIV 675
Y+ N+ K V+ I +HGDAA + QGVV ET+++++ AY+ GTIHIV
Sbjct: 355 LYKDQIHKTILNKNYKIQQNIVLPITIHGDAAISAQGVVQETLNMANTRAYSVGGTIHIV 414
Query: 676 ANNQIGFTT 702
NNQIGFTT
Sbjct: 415 INNQIGFTT 423
>UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Oxoglutarate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 901
Score = 169 bits (412), Expect = 5e-41
Identities = 90/234 (38%), Positives = 136/234 (58%), Gaps = 4/234 (1%)
Frame = +1
Query: 34 SLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEIL 213
S ++ W+ Q+ E N K+ K+ L+ LT++ E F+ ++ KRF +EG + +
Sbjct: 137 SPKEVQWLTQQFEN-NPAKLALADKKDALSSLTKAETLEKFVHTRYVGTKRFSVEGADSI 195
Query: 214 IPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG----LEAEDDG 381
+P M +++ T V+ + +GM HRGR+N+L N KP +F F G E +D
Sbjct: 196 LPMMDTLVNKGTAQQVQEVFVGMAHRGRVNILVNFFGKPEEYVFGDFNGPLELAEPIEDF 255
Query: 382 SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 561
DVKYHLG E+ + LA NPSHLE V+ V G RA Q G + K V
Sbjct: 256 DNDVKYHLGYVTEKKTPTGTCKVTLAY--NPSHLETVNAVALGMARAAQDQIGASGKKNV 313
Query: 562 MSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
+ +L+HGDAAFAGQG+V ET+ ++ + +++T GTIHI+ +NQ+GFTT + +RS
Sbjct: 314 VPVLIHGDAAFAGQGIVQETLQMAGVHSHSTGGTIHIIIDNQVGFTTSGKDTRS 367
>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Coxiella burnetii
Length = 934
Score = 164 bits (398), Expect = 2e-39
Identities = 87/243 (35%), Positives = 143/243 (58%), Gaps = 3/243 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEP--PNVTKMNADQKRLILARLTRSTGFENFLAKKWSS 177
+IG+++ I+ + NW+R +E P++ + + + KR IL +L + E +L K+
Sbjct: 163 SIGVQYSTISDERERNWLRDYVEQRLPSI-EFDKETKRNILQQLVTAESLEKYLDTKYVG 221
Query: 178 EKRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFA 357
+ R+ LEG + LIP + ++ + +E I++ M HRGR+NVL N+ + +LF +F
Sbjct: 222 QVRYSLEGGDSLIPLLDELTKRARHQKIEEIVICMAHRGRVNVLLNIMGQSAAELFQEFE 281
Query: 358 GLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
G + SGDVKYH G R + I L++ NPSHLE + PV G RA Q +
Sbjct: 282 GKKDYGLMSGDVKYHRG--YSRDVKTDAGPIHLSLAFNPSHLEFICPVAMGSVRARQERQ 339
Query: 538 GDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT-DPRH 714
++ M++++HGDA+F+G+G+V E + +S A+ G+IHI+ NNQ+GFTT +P
Sbjct: 340 NGHKRDYAMTVMIHGDASFSGEGIVMEALSMSQTRAHHVGGSIHIILNNQVGFTTSNPHD 399
Query: 715 SRS 723
+RS
Sbjct: 400 ARS 402
>UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family
protein - Tetrahymena thermophila SB210
Length = 1004
Score = 163 bits (396), Expect = 4e-39
Identities = 93/248 (37%), Positives = 147/248 (59%), Gaps = 8/248 (3%)
Frame = +1
Query: 1 DNIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
D +G+EF +N + W+ E +T++ + +K I + L+++ ++FL KK+ +
Sbjct: 175 DTVGVEFEHVNDPAERTWLYYNFERHQLTELTSFEKVNIHSLLSQTEALDHFLHKKFQTF 234
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KR+ EG E I +K ++ ++++GVE ++GMPHRGRLNVL N+ P+ L + +G
Sbjct: 235 KRYAGEGAESSIVGLKTILAKASEMGVEDAVIGMPHRGRLNVLCNLLDYPVADLLRKISG 294
Query: 361 ---LEAE-DDGSGDVKYHLGTYIE-RLNRVT---NKNIRLAVCANPSHLEAVDPVVQGKT 516
L E + DV H+ + +L T + I +++ NPSHLEAV+PV GK
Sbjct: 295 HPDLPNELYNYIDDVVSHIAVSKKGKLYAGTGCKERPINVSLLHNPSHLEAVNPVSMGKA 354
Query: 517 RAEQFYRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGF 696
RA+ + E V++I LHGDAAF+ QGVV+E+ L +P ++ GTIH++ NNQIGF
Sbjct: 355 RAKMDEKTKTE---VLNIQLHGDAAFSAQGVVYESFALGKVPKFSVGGTIHMIVNNQIGF 411
Query: 697 TTDPRHSR 720
TT+P R
Sbjct: 412 TTNPIDGR 419
>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Dichelobacter nodosus VCS1703A|Rep:
2-oxoglutarate dehydrogenase, E1 component -
Dichelobacter nodosus (strain VCS1703A)
Length = 917
Score = 162 bits (394), Expect = 7e-39
Identities = 95/249 (38%), Positives = 143/249 (57%), Gaps = 9/249 (3%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEP-PNVTKMNADQKRLILARLTRSTGFENFLAKKWSSE 180
+I +E I + +W+ +E ++A Q+ +L +L + FE +L +++ +
Sbjct: 150 HIALETSHIEEQTESDWLYHYLETYAGKYPISAAQQHELLTQLIAADRFEQYLHQRYVGQ 209
Query: 181 KRFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG 360
KRF LEG + LIP + Q+I G + + + M HRGRLNVLA+V KP ++F +F G
Sbjct: 210 KRFSLEGGDALIPLLNQLIMELAHNGAQQLCLAMAHRGRLNVLAHVLGKPAARIFAEFEG 269
Query: 361 LEAEDDG-SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
A +GDVKYHLG + R+ + ++++L++ NPSHLE V+ V G RA+ +
Sbjct: 270 QTASAAPINGDVKYHLG-FTARV-QYQAQSVQLSLMYNPSHLEFVNAVALGFARAQLEHC 327
Query: 538 GDNEG-------KKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGF 696
+ EG KV+ IL+HGDAA +GQG+ E + LS L Y G +HIV NNQIGF
Sbjct: 328 SEKEGATIMAAADKVVPILIHGDAALSGQGINQEVLQLSQLRGYFCGGAVHIVVNNQIGF 387
Query: 697 TTDPRHSRS 723
TT +RS
Sbjct: 388 TTTKTDARS 396
>UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Burkholderiaceae|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Burkholderia phymatum STM815
Length = 891
Score = 161 bits (390), Expect = 2e-38
Identities = 91/221 (41%), Positives = 129/221 (58%), Gaps = 4/221 (1%)
Frame = +1
Query: 52 WIRQRMEPPNVTKMNADQKR-LILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIPAMK 228
W+ RME V Q+R +L RL +E +A + KRF LEGCE L+P +
Sbjct: 147 WLFNRMESELVCPQPTPQERDALLRRLLTVEMWERLVASRHGHAKRFSLEGCESLVPLLD 206
Query: 229 QVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSG---DVKY 399
+I+ S GV+ I +GMPHRGRLN L N+ P+ ++ A L+ E D + D+ Y
Sbjct: 207 ALIESSAIDGVQQIFLGMPHRGRLNALVNLMDFPVAEM---LACLDHESDIAAMQTDLPY 263
Query: 400 HLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKVMSILLH 579
HLG L R + I L + NPSHL++V PVV G RA ++ ++ + +++H
Sbjct: 264 HLGG--AALKRTAHGEIALLLAHNPSHLQSVYPVVSGMARA---WQDEHLDAACVPVVVH 318
Query: 580 GDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
GDAAFAGQG+V ET++++ YT GTIH++ NNQIGFTT
Sbjct: 319 GDAAFAGQGIVMETLNMTRKSGYTLGGTIHVIVNNQIGFTT 359
>UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase
domain-containing protein 1; n=39; Eumetazoa|Rep:
Dehydrogenase E1 and transketolase domain-containing
protein 1 - Homo sapiens (Human)
Length = 919
Score = 161 bits (390), Expect = 2e-38
Identities = 87/251 (34%), Positives = 142/251 (56%), Gaps = 12/251 (4%)
Frame = +1
Query: 7 IGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKR 186
I IE + S ++ +W +R E ++++ + + S F++FLA K+S+ KR
Sbjct: 130 ISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKR 189
Query: 187 FGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE 366
+G EG E ++ +++ +S G+ +I+GMPHRGRLN+L + + P +F + GL
Sbjct: 190 YGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLS 249
Query: 367 AEDD---GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR 537
+ +GDV HL + ++ L + + + + NPSHLEAV+PV GKTR Q R
Sbjct: 250 EFPENFSATGDVLSHLTSSVD-LYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSR 308
Query: 538 GDNE---------GKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQI 690
D + G +V+ + +HGDA+F GQG+V ET LS+LP + G++H++ NNQ+
Sbjct: 309 QDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQL 368
Query: 691 GFTTDPRHSRS 723
G+TT RS
Sbjct: 369 GYTTPAERGRS 379
>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
putative; n=2; Theileria|Rep: 2-oxoglutarate
dehydrogenase e1 component, putative - Theileria parva
Length = 1030
Score = 159 bits (385), Expect = 8e-38
Identities = 81/237 (34%), Positives = 130/237 (54%), Gaps = 3/237 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
NI EF I + E+ ++ +E K N + + ++ FE F AK + + K
Sbjct: 188 NISFEFGHIANSEEVAFLINEIESDEFLKFNKNDHLKCFKSICKAVKFEQFCAKTFPTLK 247
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGL 363
RFG++G E ++ ++ + + G+ SI+M M HRGRLNVL N KPL + F +F G
Sbjct: 248 RFGMDGIESILLLLESIEENGRNFGINSIMMTMSHRGRLNVLCNFLNKPLQESFAEFRGA 307
Query: 364 EAEDDG---SGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFY 534
+ SGDVKYH G R T + + + +N SHL+ PV+ G +A+Q+Y
Sbjct: 308 NWFINSHFRSGDVKYHNGY------RTTKNGVEIQMISNSSHLQFSHPVLTGLVKAKQYY 361
Query: 535 RGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTD 705
D K++ I +HG++A +GQG+ +E + ++ + + GTI+I+ NNQIGFT +
Sbjct: 362 ENDTNQSKILPIAIHGNSAISGQGMPYEVVQMAKIDGFGIGGTINIIVNNQIGFTAN 418
>UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_10,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 893
Score = 155 bits (376), Expect = 1e-36
Identities = 87/243 (35%), Positives = 144/243 (59%), Gaps = 4/243 (1%)
Frame = +1
Query: 4 NIGIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEK 183
++G+EF I E+ W+ + E ++ + I L + +++ KK+++ K
Sbjct: 112 SVGVEFEQIEDPEEKQWLHENYEKFMNEEITQADRVSIHNLLVQMEAIDHYYHKKFTTFK 171
Query: 184 RFGLEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG- 360
R+ EG E +I A++ + + +LGV ++ M HRGR +++++ P +F + G
Sbjct: 172 RYAGEGGEGVIVALRAIYGQAVELGVTDVVQSMAHRGRFPLMSSLLDFPPSDIFRKIMGE 231
Query: 361 --LEAEDD-GSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQF 531
L E G DV +HL T ++ + NK++ + V NPSHLEA +PV QGK +A+Q
Sbjct: 232 NDLPQEYTFGVDDVVHHLSTSNKK--KFNNKDLTITVVHNPSHLEAANPVSQGKAKAKQD 289
Query: 532 YRGDNEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPR 711
G+ + +V+++ LHGDAAFAGQG+V+E+M LS L Y+ GT+HI+ NNQIG+TT+ +
Sbjct: 290 DYGNID--QVLNLQLHGDAAFAGQGIVYESMLLSGLDNYSNGGTVHIIQNNQIGYTTNIK 347
Query: 712 HSR 720
SR
Sbjct: 348 DSR 350
>UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3;
Bilateria|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 911
Score = 155 bits (375), Expect = 1e-36
Identities = 89/250 (35%), Positives = 135/250 (54%), Gaps = 13/250 (5%)
Frame = +1
Query: 13 IEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFG 192
IEFM IN+ E+ WI Q E ++ ++ I + + F+ FL+ K+ + KR+G
Sbjct: 122 IEFMHINNWEERQWISQNFENCIAEELRKEELLRIGDLMLKCENFDKFLSTKFPTLKRYG 181
Query: 193 LEGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG---L 363
EG E + ++ + + + VE II+G+ HRGRLN+L + P +F + G
Sbjct: 182 AEGAESMFAFFSELFEGAAEKQVEEIIIGIAHRGRLNLLTQLMDFPPVHMFRKIKGRAEF 241
Query: 364 EAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAE--QFYR 537
D +GDV HL + + + + N+ + + NPSHLEAV+PV GK RA +
Sbjct: 242 PESADAAGDVLSHLVSSFD--YKGSEGNVHVTMLPNPSHLEAVNPVAMGKARARAWSMNK 299
Query: 538 GD--------NEGKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIG 693
GD G V+++L+HGD AF GQGVV+E++ LS P + GT+H+V NNQI
Sbjct: 300 GDYSPDERSARAGDSVLNVLVHGDGAFTGQGVVWESIALSQAPHFRLGGTVHLVTNNQIA 359
Query: 694 FTTDPRHSRS 723
FT + RS
Sbjct: 360 FTAESSVGRS 369
>UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p -
Drosophila melanogaster (Fruit fly)
Length = 919
Score = 151 bits (367), Expect = 1e-35
Identities = 78/247 (31%), Positives = 140/247 (56%), Gaps = 11/247 (4%)
Frame = +1
Query: 16 EFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGL 195
EF ++ +E+ W+ + E + ++ ++ I L +S ++NF+A K+ + KR+G
Sbjct: 135 EFSYVEDIEEREWLARNFETLDQQQLGKSERCEIAELLIKSQAWDNFMALKFPTVKRYGG 194
Query: 196 EGCEILIPAMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLE--A 369
EG E ++ Q++ S + +E +++ MPHRGR + A + ++F + G +
Sbjct: 195 EGAESMLAFFWQLLRDSVQANIEHVVLAMPHRGRTPLQAALLNMRPAKVFRKLGGASEFS 254
Query: 370 ED-DGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDN 546
ED + DV H ++ ++ K + ++ NPSHLEA +PV GKTR++Q RG+
Sbjct: 255 EDIEAMSDVISHF--HVSEQLKILGKKLSFSMVRNPSHLEAANPVAMGKTRSKQQARGEG 312
Query: 547 E--------GKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTT 702
G+ V++++LHGDAAFAGQG+ E ++++ +P + G++H++ NNQ+GFTT
Sbjct: 313 AFGDGSQPFGEHVLNVILHGDAAFAGQGINQECLNMAYVPHFEVGGSLHLIVNNQVGFTT 372
Query: 703 DPRHSRS 723
RS
Sbjct: 373 PGDRGRS 379
>UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 730
Score = 128 bits (310), Expect = 1e-28
Identities = 75/155 (48%), Positives = 91/155 (58%), Gaps = 7/155 (4%)
Frame = +1
Query: 280 MPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGT--YIERLNRVTNKNIR 453
M HRGRLNVL NV KPL + + + GDV+YHLG ++ K +
Sbjct: 1 MAHRGRLNVLHNVFGKPLGAICAEIVD-DRSSFLVGDVRYHLGARAVVDVDVERGAKQVA 59
Query: 454 LAVCANPSHLEAVDPVVQGKTRAEQFYR-GDNEGKK----VMSILLHGDAAFAGQGVVFE 618
L + NPSHLE V+ VV G RA+QF R EG V+ +LLHGDA+F G G E
Sbjct: 60 LTLVPNPSHLEMVNAVVSGVVRAKQFKRDSQTEGASARAHVLPLLLHGDASFCGLGQNGE 119
Query: 619 TMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
M L DLP YTT GT+H+V NNQIGFTT PR +RS
Sbjct: 120 VMQLQDLPDYTTGGTVHVVVNNQIGFTTVPRRARS 154
>UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;
Aspergillus|Rep: Contig An06c0020, complete genome -
Aspergillus niger
Length = 456
Score = 103 bits (248), Expect = 3e-21
Identities = 63/149 (42%), Positives = 85/149 (57%), Gaps = 2/149 (1%)
Frame = +1
Query: 259 VESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGS-GDVKYHLGTYIERLNRV 435
+E I MG+ HRGR+N L N+ K + F E G GDVKYH G R+
Sbjct: 1 MELIEMGLGHRGRMNALYNIVGKDGPSMLRDFDSKETSAWGMRGDVKYHYGGSGARVTP- 59
Query: 436 TNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYR-GDNEGKKVMSILLHGDAAFAGQGVV 612
+ + + + + PS++E+V+PVV GKTRA Q R GD E K M + +H DAAFAGQ V
Sbjct: 60 SGRKVYMNMAPQPSNVESVNPVVMGKTRAIQDRRNGDRE--KTMMLNVHTDAAFAGQKTV 117
Query: 613 FETMHLSDLPAYTTHGTIHIVANNQIGFT 699
+ET+ L+ L Y GT+ + NNQ FT
Sbjct: 118 YETLGLAGLNGYEIGGTLRFIVNNQGLFT 146
>UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura
dioica|Rep: CG1544-PA-like protein - Oikopleura dioica
(Tunicate)
Length = 886
Score = 97.1 bits (231), Expect = 4e-19
Identities = 67/234 (28%), Positives = 116/234 (49%), Gaps = 6/234 (2%)
Frame = +1
Query: 40 EQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFGLEGCEILIP 219
EQ ++IR + +A IL +L + F+ FLA ++ KR+GLEG E ++
Sbjct: 134 EQQHFIRSELALIEKESSDASHTGYIL-QLAKE--FDEFLALRFPDVKRYGLEGSETIML 190
Query: 220 AMKQVIDVSTKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAG-----LEAEDDGS 384
+++ K + +GM HRGR N+L + +F + +G + E +
Sbjct: 191 WFDTILNEVDK--DNHVTIGMTHRGRNNLLVCLLGLRADIMFGKMSGKPEFPFDPEHEKI 248
Query: 385 -GDVKYHLGTYIERLNRVTNKNIRLAVCANPSHLEAVDPVVQGKTRAEQFYRGDNEGKKV 561
GDV HL +++ + + +++ NPSHL+A++P GK R++ + G K
Sbjct: 249 IGDVLSHL-----QISSTLDSGVSVSLLPNPSHLDAINPAAMGKARSKM-----DHGGKA 298
Query: 562 MSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
+ I HGD + GQG E +++ ++P Y G++H +NQ+ FT SRS
Sbjct: 299 LCIQCHGDGSLIGQGHNHEILNMQNIPGYDVGGSLHFCCDNQVAFTASGNLSRS 352
>UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 334
Score = 81.4 bits (192), Expect = 2e-14
Identities = 36/70 (51%), Positives = 50/70 (71%)
Frame = +1
Query: 10 GIEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRF 189
G+E++ I EQC+W+R R+E K + D+KR IL RL S+ FE+FLA K+ ++KRF
Sbjct: 235 GVEYIHIPDREQCDWLRARIEVDKPFKYSIDEKRRILDRLIWSSSFESFLATKYPNDKRF 294
Query: 190 GLEGCEILIP 219
GLEGCE L+P
Sbjct: 295 GLEGCETLVP 304
>UniRef50_UPI0000E46CA4 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 244
Score = 72.9 bits (171), Expect = 7e-12
Identities = 31/58 (53%), Positives = 41/58 (70%)
Frame = +1
Query: 550 GKKVMSILLHGDAAFAGQGVVFETMHLSDLPAYTTHGTIHIVANNQIGFTTDPRHSRS 723
G KV+++LLHGDAAF QGV+ E +++LP Y G+IH++ NNQIGFTT RS
Sbjct: 19 GDKVINVLLHGDAAFVAQGVIAECFAMANLPHYAVGGSIHLIVNNQIGFTTPSERGRS 76
>UniRef50_Q9KJ66 Cluster: Irb5; n=1; Vibrio cholerae|Rep: Irb5 -
Vibrio cholerae
Length = 53
Score = 37.5 bits (83), Expect = 0.33
Identities = 16/27 (59%), Positives = 19/27 (70%)
Frame = +1
Query: 448 IRLAVCANPSHLEAVDPVVQGKTRAEQ 528
+ LA+ NPSHLE V+PVV G RA Q
Sbjct: 1 VHLALAFNPSHLEIVNPVVMGSVRARQ 27
>UniRef50_A3Z1Y0 Cluster: Serine protease, subtilase family protein;
n=1; Synechococcus sp. WH 5701|Rep: Serine protease,
subtilase family protein - Synechococcus sp. WH 5701
Length = 692
Score = 35.1 bits (77), Expect = 1.8
Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Frame = -2
Query: 576 QQDRHHLLALVVSPVELLGSGLALHHGVDGLQVRGVRANSQSNVLVGNAIQTLDVR-AQV 400
Q DR+ + L + VE L + L+ H+G+ V + +NS+ L+ +I T+ R AQ+
Sbjct: 404 QLDRYVAVNLTRAEVETLAASLSQHYGIASPAVYRMFSNSKKKALISESIHTVQARTAQL 463
Query: 399 IFHVAG 382
++ G
Sbjct: 464 GYNAYG 469
>UniRef50_Q1MRZ5 Cluster: Hyphotheical protein; n=1; Lawsonia
intracellularis PHE/MN1-00|Rep: Hyphotheical protein -
Lawsonia intracellularis (strain PHE/MN1-00)
Length = 554
Score = 34.7 bits (76), Expect = 2.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +1
Query: 247 TKLGVESIIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERL 426
T+ + +II P R +V++ C++P + F L D+GSGD+ + +R+
Sbjct: 127 TEQAIINIIATAPSGHRKSVISAFCQEPFNIFEKNFNKLRGSDEGSGDLSHTKLKVAQRV 186
Query: 427 -NRVTNKNI 450
R+T K I
Sbjct: 187 AARITQKKI 195
>UniRef50_Q00160 Cluster: Uncharacterized gene 37 protein; n=1;
Ictalurid herpesvirus 1|Rep: Uncharacterized gene 37
protein - Ictalurid herpesvirus 1 (IcHV-1) (Channel
catfish herpesvirus)
Length = 670
Score = 33.9 bits (74), Expect = 4.1
Identities = 22/84 (26%), Positives = 41/84 (48%)
Frame = +1
Query: 13 IEFMFINSLEQCNWIRQRMEPPNVTKMNADQKRLILARLTRSTGFENFLAKKWSSEKRFG 192
I+FMF++SL + R+ P VTK+ + ++ ++ T E F A+ +
Sbjct: 577 IQFMFVDSLNAPGVLMDRLYPSKVTKLTFTELMVLSEKVETVTLPEIFAAQIGLNPSEVR 636
Query: 193 LEGCEILIPAMKQVIDVSTKLGVE 264
L+ + P + V V+ +LGV+
Sbjct: 637 LKNRDACEPPREIVTGVNHELGVD 660
>UniRef50_Q0TE31 Cluster: Putative membrane protein; n=10;
Enterobacteriaceae|Rep: Putative membrane protein -
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length = 1143
Score = 33.5 bits (73), Expect = 5.4
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Frame = +1
Query: 328 PLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKNIRLAVCANPSHL--EAVDPV 501
PL + F L + G GD + L TY+ R+ RV K ++ +P + + V
Sbjct: 785 PLDKTFAPLLRLLGDKAGGGDSQLSLQTYLTRVTRVRLKLQQVTNAPDPQEMTQQLAQTV 844
Query: 502 VQGKT 516
+QGKT
Sbjct: 845 LQGKT 849
>UniRef50_Q7ULX8 Cluster: NifS-like aminotranfserase-putative
cysteine desulfurase; n=1; Pirellula sp.|Rep: NifS-like
aminotranfserase-putative cysteine desulfurase -
Rhodopirellula baltica
Length = 395
Score = 33.1 bits (72), Expect = 7.1
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Frame = -2
Query: 507 LHHGVDGLQVRGVRANSQSNV-LVGNA-IQTLDVRAQVIFHVAGTIILSFETGELCEQLV 334
LH +DGLQ+ G + S+V L GN ++ DV + +A T ++F +G C
Sbjct: 288 LHESIDGLQLNGANWHDDSSVRLPGNLNVRLRDVEGEA--WMAATPEVAFSSGSACSS-T 344
Query: 333 QRLTAHV 313
+ L +HV
Sbjct: 345 EALPSHV 351
>UniRef50_A0JY86 Cluster: Putative uncharacterized protein; n=2;
Arthrobacter|Rep: Putative uncharacterized protein -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 33.1 bits (72), Expect = 7.1
Identities = 22/57 (38%), Positives = 27/57 (47%)
Frame = -2
Query: 552 ALVVSPVELLGSGLALHHGVDGLQVRGVRANSQSNVLVGNAIQTLDVRAQVIFHVAG 382
AL S G G LHH +DG VR + L GNA+ T D A +F V+G
Sbjct: 203 ALCASAANRRGWGDGLHHVLDGTTGAPVRTVVATWALAGNAM-TADALATALFFVSG 258
>UniRef50_Q2NB23 Cluster: Protein-tyrosine-phosphatase; n=6;
Alphaproteobacteria|Rep: Protein-tyrosine-phosphatase -
Erythrobacter litoralis (strain HTCC2594)
Length = 157
Score = 32.7 bits (71), Expect = 9.4
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 4/38 (10%)
Frame = +1
Query: 307 LANVCRKPLHQLF----TQFAGLEAEDDGSGDVKYHLG 408
L N+CR PL + + AGL+AE D +G YH+G
Sbjct: 12 LGNICRSPLAEAAFRKASADAGLDAEADSAGTAAYHVG 49
>UniRef50_Q1D6W3 Cluster: Putative uncharacterized protein; n=1;
Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
protein - Myxococcus xanthus (strain DK 1622)
Length = 141
Score = 32.7 bits (71), Expect = 9.4
Identities = 23/66 (34%), Positives = 31/66 (46%)
Frame = -2
Query: 576 QQDRHHLLALVVSPVELLGSGLALHHGVDGLQVRGVRANSQSNVLVGNAIQTLDVRAQVI 397
Q R L +L V + LL LAL HG DG+ V G + LV ++T D + Q +
Sbjct: 4 QPVRPRLTSLAVVTLALLTPALALAHGKDGVHVMGTVKEVKQAALV---LETSDKKQQEV 60
Query: 396 FHVAGT 379
GT
Sbjct: 61 MTDPGT 66
>UniRef50_Q029Y8 Cluster: NHL repeat containing protein; n=2;
Bacteria|Rep: NHL repeat containing protein - Solibacter
usitatus (strain Ellin6076)
Length = 380
Score = 32.7 bits (71), Expect = 9.4
Identities = 14/20 (70%), Positives = 16/20 (80%)
Frame = -2
Query: 438 GNAIQTLDVRAQVIFHVAGT 379
GNA+ +DVRA IFHVAGT
Sbjct: 260 GNAVYRMDVRAGKIFHVAGT 279
>UniRef50_Q9ST86 Cluster: CAA303711.1 protein; n=2; Oryza
sativa|Rep: CAA303711.1 protein - Oryza sativa (Rice)
Length = 764
Score = 32.7 bits (71), Expect = 9.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = +2
Query: 320 AVSLCTSCSHSSPVSKLRMMVP 385
AV+LC +CSH SPVS LR P
Sbjct: 352 AVTLCRACSHLSPVSPLRSKPP 373
>UniRef50_A5DBM7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 1112
Score = 32.7 bits (71), Expect = 9.4
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Frame = +1
Query: 268 IIMGMPHRGRLNVLANVCRKPLHQLFTQFAGLEAEDDGSGDVKYHLGTYIERLNRVTNKN 447
++ G P G+ ++ ++ L + F Q L D S +++ H TY+ + V ++
Sbjct: 612 MLAGPPGTGKTSLAKSIANS-LGRSF-QRVSLGGIKDES-EIRGHRRTYVGAMPGVIIQS 668
Query: 448 IRLAVCANP-SHLEAVDPVVQGKTRAEQFYRGD 543
+R A C NP L+ +D V+ G + A +F GD
Sbjct: 669 LRKARCMNPVILLDEIDKVIGGNSNANKF-NGD 700
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 762,374,927
Number of Sequences: 1657284
Number of extensions: 15988695
Number of successful extensions: 51554
Number of sequences better than 10.0: 90
Number of HSP's better than 10.0 without gapping: 48888
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51327
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 58677691418
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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