Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0146
(701 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 184 1e-45
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 170 3e-41
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 166 4e-40
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 162 7e-39
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 159 6e-38
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 157 2e-37
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 157 2e-37
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 156 6e-37
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 153 5e-36
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 152 7e-36
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 151 2e-35
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 150 4e-35
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 150 4e-35
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 149 5e-35
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 149 9e-35
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 148 2e-34
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 146 3e-34
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 146 6e-34
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 143 3e-33
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 143 4e-33
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 142 7e-33
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 141 2e-32
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 141 2e-32
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 140 4e-32
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 138 2e-31
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 137 2e-31
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 136 4e-31
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 135 9e-31
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 134 2e-30
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 134 3e-30
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 132 8e-30
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 132 8e-30
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 131 2e-29
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 131 2e-29
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 131 2e-29
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 129 7e-29
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 129 7e-29
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 129 7e-29
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 125 9e-28
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 125 9e-28
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 124 2e-27
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 124 3e-27
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 124 3e-27
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 123 4e-27
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 123 5e-27
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 122 6e-27
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 122 9e-27
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 122 9e-27
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 120 3e-26
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 119 6e-26
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 119 8e-26
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 118 1e-25
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 118 1e-25
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 118 1e-25
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 118 2e-25
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 117 2e-25
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 117 2e-25
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 116 6e-25
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 116 6e-25
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 116 7e-25
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 116 7e-25
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 116 7e-25
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 116 7e-25
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 115 1e-24
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 115 1e-24
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 115 1e-24
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 115 1e-24
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 114 2e-24
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 114 2e-24
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 113 4e-24
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 113 4e-24
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 112 7e-24
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 112 7e-24
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 112 7e-24
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 112 7e-24
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 112 9e-24
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 112 9e-24
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 112 9e-24
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 112 9e-24
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 111 1e-23
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 111 1e-23
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 111 1e-23
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 111 1e-23
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 111 1e-23
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 111 2e-23
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 111 2e-23
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 110 3e-23
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 110 4e-23
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 109 5e-23
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 109 6e-23
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 108 1e-22
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 107 3e-22
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 107 3e-22
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 106 5e-22
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 106 6e-22
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 106 6e-22
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 105 8e-22
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 105 8e-22
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 105 1e-21
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 105 1e-21
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 104 2e-21
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 104 2e-21
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 104 2e-21
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 104 2e-21
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 104 2e-21
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 104 2e-21
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 104 2e-21
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 103 3e-21
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 103 3e-21
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 103 4e-21
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 103 4e-21
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 103 4e-21
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 103 6e-21
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 102 7e-21
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 102 7e-21
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 102 1e-20
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 102 1e-20
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 101 1e-20
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 101 1e-20
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 101 1e-20
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 101 2e-20
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 101 2e-20
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 101 2e-20
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 101 2e-20
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 101 2e-20
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 101 2e-20
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 101 2e-20
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 100 3e-20
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 100 3e-20
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 100 4e-20
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 100 4e-20
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 100 4e-20
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 100 4e-20
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 100 4e-20
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 99 5e-20
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 100 7e-20
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 100 7e-20
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 100 7e-20
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 100 7e-20
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 100 7e-20
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 99 9e-20
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 99 9e-20
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 99 1e-19
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 99 1e-19
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 98 2e-19
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 98 2e-19
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 98 2e-19
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 97 3e-19
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 97 4e-19
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 97 4e-19
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 97 4e-19
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 97 4e-19
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 97 5e-19
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 97 5e-19
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 97 5e-19
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 96 6e-19
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 96 6e-19
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 96 8e-19
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 96 8e-19
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 96 8e-19
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 96 8e-19
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 95 1e-18
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 95 1e-18
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 95 2e-18
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 95 2e-18
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 94 3e-18
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 94 3e-18
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 5e-18
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 93 5e-18
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 93 6e-18
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 93 8e-18
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 93 8e-18
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 93 8e-18
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 92 1e-17
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 92 1e-17
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 92 1e-17
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 92 1e-17
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 92 1e-17
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 92 1e-17
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 91 2e-17
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 91 2e-17
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 91 2e-17
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 91 2e-17
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 90 4e-17
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 90 4e-17
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 90 4e-17
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 90 6e-17
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 89 7e-17
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 89 7e-17
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 89 1e-16
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 89 1e-16
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 89 1e-16
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 89 1e-16
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 89 1e-16
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 88 2e-16
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 88 2e-16
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 88 2e-16
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 87 3e-16
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 87 3e-16
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 86 7e-16
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 86 7e-16
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 86 7e-16
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 86 9e-16
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 85 1e-15
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 85 2e-15
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 85 2e-15
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 85 2e-15
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 85 2e-15
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 85 2e-15
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 84 3e-15
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 84 3e-15
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 84 4e-15
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 83 5e-15
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 83 6e-15
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 83 6e-15
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 83 6e-15
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 82 1e-14
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 82 1e-14
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 82 1e-14
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 82 1e-14
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 81 3e-14
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 81 3e-14
UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 81 3e-14
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 81 3e-14
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 81 3e-14
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 80 6e-14
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 80 6e-14
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 79 8e-14
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 79 8e-14
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 79 1e-13
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 79 1e-13
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 79 1e-13
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 79 1e-13
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 79 1e-13
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 78 2e-13
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 77 4e-13
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 77 4e-13
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 76 7e-13
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 76 7e-13
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 1e-12
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 74 3e-12
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 74 3e-12
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 74 4e-12
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 73 5e-12
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 73 7e-12
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 71 2e-11
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 71 3e-11
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 70 5e-11
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 70 5e-11
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 70 6e-11
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 70 6e-11
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 69 1e-10
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 69 1e-10
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 68 2e-10
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 68 2e-10
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 68 3e-10
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 68 3e-10
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 67 3e-10
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 66 6e-10
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 66 6e-10
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 66 1e-09
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 66 1e-09
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 66 1e-09
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 65 2e-09
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 65 2e-09
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 65 2e-09
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 64 2e-09
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 64 3e-09
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 64 4e-09
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 64 4e-09
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 63 6e-09
UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 63 6e-09
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 63 6e-09
UniRef50_Q8YUM4 Cluster: Aldo/keto reductase; n=4; Nostocaceae|R... 62 1e-08
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 60 5e-08
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 60 7e-08
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 60 7e-08
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 59 9e-08
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 59 1e-07
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 58 2e-07
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 58 3e-07
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_Q8ZYV2 Cluster: Oxidoreductase, conjectural; n=3; Pyrob... 57 5e-07
UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal... 56 6e-07
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 56 6e-07
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 56 8e-07
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 56 8e-07
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 56 8e-07
UniRef50_Q5FJ72 Cluster: Predicted oxidoreductase; n=1; Lactobac... 56 1e-06
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 56 1e-06
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 55 1e-06
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 55 1e-06
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 55 1e-06
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 55 2e-06
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 55 2e-06
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 54 3e-06
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 54 4e-06
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 4e-06
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 6e-06
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 53 6e-06
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 53 6e-06
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 52 1e-05
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 52 1e-05
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 52 1e-05
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 52 1e-05
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 52 2e-05
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 51 2e-05
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 50 7e-05
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 49 1e-04
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 49 1e-04
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 49 1e-04
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_P25906 Cluster: Putative oxidoreductase ydbC; n=58; Bac... 49 1e-04
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 2e-04
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 48 2e-04
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 48 2e-04
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 48 2e-04
UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 48 3e-04
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_A1C8R6 Cluster: Aldo-keto reductase (YakC), putative; n... 48 3e-04
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 48 3e-04
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 47 4e-04
UniRef50_Q9RT75 Cluster: Oxidoreductase, putative; n=3; cellular... 47 5e-04
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 47 5e-04
UniRef50_Q3DEH0 Cluster: Putative uncharacterized protein; n=2; ... 47 5e-04
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 47 5e-04
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 47 5e-04
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 46 9e-04
UniRef50_A3I2P1 Cluster: Putative oxidoreductase-possibly Aldo/k... 46 0.001
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 45 0.002
UniRef50_Q88ZZ9 Cluster: Oxidoreductase; n=5; Lactobacillales|Re... 45 0.002
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 44 0.003
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 44 0.005
UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 44 0.005
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005
UniRef50_Q1IPE6 Cluster: Aldo/keto reductase; n=21; Bacteria|Rep... 43 0.006
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 43 0.006
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 43 0.006
UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des... 43 0.006
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 43 0.008
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 43 0.008
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.011
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 42 0.011
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 42 0.011
UniRef50_Q5FK29 Cluster: Oxidoreductase; n=1; Lactobacillus acid... 42 0.015
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 42 0.015
UniRef50_A2G8W6 Cluster: Putative uncharacterized protein; n=1; ... 42 0.015
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 42 0.019
UniRef50_Q2GTV5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_A3DM42 Cluster: Aldo/keto reductase; n=1; Staphylotherm... 42 0.019
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 41 0.026
UniRef50_Q64UL3 Cluster: Aldo/keto reductase family oxidoreducta... 41 0.026
UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative... 41 0.026
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 41 0.026
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 41 0.034
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 41 0.034
UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 40 0.045
UniRef50_Q0RGG9 Cluster: Putative oxidoreductase; n=1; Frankia a... 40 0.045
UniRef50_A1UMU2 Cluster: Aldo/keto reductase; n=7; Bacteria|Rep:... 40 0.045
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 40 0.045
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.045
UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 40 0.045
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 40 0.045
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 40 0.045
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 40 0.059
UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;... 40 0.059
UniRef50_Q1XGM4 Cluster: Putative aldo/keto reductase protein; n... 40 0.078
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 40 0.078
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 40 0.078
UniRef50_A0ZZI9 Cluster: Possible oxidoreductase in aldo-keto re... 40 0.078
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 40 0.078
UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 39 0.10
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 39 0.10
UniRef50_Q2UHM0 Cluster: Predicted protein; n=1; Aspergillus ory... 39 0.10
UniRef50_P82810 Cluster: Morphine 6-dehydrogenase; n=1; Oryctola... 39 0.10
UniRef50_Q1VXM7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 38 0.18
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 38 0.18
UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 38 0.24
UniRef50_Q747Y9 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.24
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 38 0.32
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 38 0.32
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 37 0.42
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 37 0.42
UniRef50_UPI000023E73A Cluster: hypothetical protein FG04811.1; ... 37 0.55
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 37 0.55
UniRef50_Q8A8Q2 Cluster: Aldo/keto reductase; n=3; Bacteroidales... 37 0.55
UniRef50_A7DBQ3 Cluster: Aldo/keto reductase precursor; n=2; Met... 37 0.55
UniRef50_A5C803 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55
UniRef50_Q5UQL2 Cluster: Putative F-box and FNIP repeat-containi... 37 0.55
UniRef50_UPI0000236B94 Cluster: UPI0000236B94 related cluster; n... 36 0.73
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 36 0.73
UniRef50_Q2HBZ7 Cluster: Putative uncharacterized protein; n=1; ... 36 0.73
UniRef50_Q9SAC2 Cluster: T16B5.5 protein; n=23; Magnoliophyta|Re... 36 0.96
UniRef50_Q6FV29 Cluster: Similar to tr|Q02895 Saccharomyces cere... 36 0.96
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 36 1.3
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 36 1.3
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 36 1.3
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 1.3
UniRef50_A1KMW5 Cluster: Putative uncharacterized protein BCG_29... 36 1.3
UniRef50_A0QJ98 Cluster: Morphine 6-dehydrogenase; n=1; Mycobact... 36 1.3
UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 36 1.3
UniRef50_A6RNJ6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q01752 Cluster: Aryl-alcohol dehydrogenase [NADP+]; n=7... 36 1.3
UniRef50_Q7NFR4 Cluster: Gll3460 protein; n=5; Bacteria|Rep: Gll... 35 1.7
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 35 2.2
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 35 2.2
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 35 2.2
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 35 2.2
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 34 2.9
UniRef50_Q3WFS8 Cluster: Aldo/keto reductase; n=1; Frankia sp. E... 34 2.9
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 34 2.9
UniRef50_Q4E3R7 Cluster: Putative uncharacterized protein; n=2; ... 34 2.9
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=... 34 2.9
UniRef50_Q01693 Cluster: Bacterial leucyl aminopeptidase precurs... 34 2.9
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 34 3.9
UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac... 34 3.9
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 34 3.9
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 33 5.1
UniRef50_UPI000045C22B Cluster: COG0667: Predicted oxidoreductas... 33 5.1
UniRef50_UPI000018356B Cluster: UPI000018356B related cluster; n... 33 5.1
UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep... 33 5.1
UniRef50_Q3BTK7 Cluster: Putative oxidoreductase; n=1; Xanthomon... 33 5.1
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 33 5.1
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 33 5.1
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 33 5.1
UniRef50_Q3ZJ90 Cluster: DNA-directed RNA polymerase subunit bet... 33 5.1
UniRef50_Q228E8 Cluster: Regulator of chromosome condensation; n... 33 6.8
UniRef50_UPI00006CB7CC Cluster: Protein kinase domain containing... 33 9.0
UniRef50_Q03V87 Cluster: ABC-type oligopeptide transport system,... 33 9.0
UniRef50_Q9LVQ7 Cluster: Zinc finger protein; n=2; core eudicoty... 33 9.0
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 33 9.0
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 184 bits (449), Expect = 1e-45
Identities = 88/187 (47%), Positives = 120/187 (64%), Gaps = 3/187 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DYL+TW+ EE LG KSIG+SNFN Q+ +L+ IKP LQ+EV+ + Q+ LI
Sbjct: 155 DYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLIT 214
Query: 191 YCKRNGIVVMAFSPFGPM---FHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
Y K GI+VM +SPFG + F LP + DDP L ++A+K+ K+ QIVLR+L+ + V
Sbjct: 215 YAKDEGIIVMGYSPFGSLVKRFGMDLPGPKMDDPVLTSLAKKYEKTPAQIVLRWLVDRKV 274
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSDQV 541
VPIPK+V R+ ENI++FDF L E++ KI FN R SFWQ HP+YPF+
Sbjct: 275 VPIPKTVSPKRLLENINIFDFKLKEEEIEKINQFNSNTRYTLPSFWQKHPFYPFDMVPNP 334
Query: 542 HDNPFQS 562
+PF+S
Sbjct: 335 IPDPFRS 341
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 170 bits (413), Expect = 3e-41
Identities = 82/176 (46%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY+DTWK ME+ G SIG+SNFN+ Q++RIL N ++KP QVE + + Q LI+
Sbjct: 145 DYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIE 204
Query: 191 YCKRNGIVVMAFSPFG-PMFHDSLPSIRP----DDPTLVAIAEKHGKSVTQIVLRYLIQK 355
+C IVV A SPFG P + P +P D+P +V I +K KS Q+VLRYL+Q
Sbjct: 205 FCMERDIVVTAHSPFGRPHLFEKNPKDKPKPVLDEPEIVEIGKKFDKSSAQVVLRYLLQN 264
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
GVVPIPKS +++N+++FDF LSS+DM + FN +R V +S ++H YYPF
Sbjct: 265 GVVPIPKSTSAQHLKQNLEIFDFELSSDDMAILDGFNTNQRMVRLSLLKEHKYYPF 320
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 166 bits (404), Expect = 4e-40
Identities = 80/171 (46%), Positives = 114/171 (66%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DYL+TWKGMEE K GLA+SIG+SNFN+ QI R+LE +IKP QVEV+L L Q LI+
Sbjct: 395 DYLETWKGMEECKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIE 454
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+CK++ I V +SP G + + DDP + + +K+GK+ QI R++ Q G +PI
Sbjct: 455 FCKKHDITVTGYSPLGRPGNRYGITNAWDDPIIQELVKKYGKTPAQIACRFVSQLGAIPI 514
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
PKSV K+RI+EN ++FDF+L+ E++N I + +R M ++ YYPF
Sbjct: 515 PKSVTKSRIKENFEIFDFSLTDEEINSIQSIATGERVAPMEDAKESKYYPF 565
Score = 153 bits (371), Expect = 4e-36
Identities = 74/157 (47%), Positives = 108/157 (68%), Gaps = 1/157 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DYL+TWKGMEE K GLA+SIG+SNFN+ QI R+L + +IKP QVEV ++L Q LI+
Sbjct: 138 DYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIE 197
Query: 191 YCKRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+CK++ I V FSP G P + ++ D+P + +A+K+ K+ I R++ Q GV P
Sbjct: 198 FCKKHEITVTGFSPLGRPGNRHGIQNLW-DEPQIQKLAQKYKKTPANIACRFIHQLGVTP 256
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
IPKSV K+RI+EN+D+FDF+L+ E+++ I K +
Sbjct: 257 IPKSVTKSRIKENLDIFDFSLTPEEVSTIEKMGKHNK 293
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 162 bits (394), Expect = 7e-39
Identities = 78/177 (44%), Positives = 111/177 (62%), Gaps = 5/177 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
VDY+DTWK ME+ G KSIG+SNFN+ QI R+L +IKP QVE N L Q KL
Sbjct: 104 VDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQVECNPSLNQRKLT 163
Query: 188 DYCKRNGIVVMAFSPFG-PMFH----DSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
++CK I + A+SP G P ++ D++P DDP ++ I +K+ K+ Q++LRYL+
Sbjct: 164 EFCKNLDITLTAYSPLGRPNYYEKDPDNMPKPALDDPKVIEIGKKYNKTSGQVILRYLVD 223
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
G +PIPKS RI +NID+FDF L+ E++ + F+ +RTV + H Y+PF
Sbjct: 224 IGTIPIPKSSNSERIRQNIDIFDFKLTEEEIKIMDGFHTGQRTVPFNLCTSHKYFPF 280
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 159 bits (386), Expect = 6e-38
Identities = 80/177 (45%), Positives = 112/177 (63%), Gaps = 4/177 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
VD++DTWK ME+ L KSIGISNFN+ QIDR+L++ +I P + Q+E + +L Q KL
Sbjct: 313 VDFVDTWKAMEKMHEKDLTKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLR 372
Query: 188 DYCKRNGIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
+C GI V ++SP G P P + +DP + I K+GKS QI+LRY +Q
Sbjct: 373 KFCSDRGITVTSYSPLGSPARPWQKPGDPYVI-NDPKIKEIGNKYGKSPAQILLRYNVQL 431
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
G V IPKS +NR+ EN+ +FDF LS +DM IGTF+ R + ++HP+YPF+
Sbjct: 432 GNVVIPKSSNRNRLVENMSIFDFTLSEDDMKYIGTFDCNGRICPQAEAREHPFYPFK 488
Score = 110 bits (264), Expect = 4e-23
Identities = 60/153 (39%), Positives = 94/153 (61%), Gaps = 1/153 (0%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
++TW+ ME + L ++IG+SNFN+ QI+RILEN I+P V Q++ + +L Q KL YC
Sbjct: 124 IETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYC 183
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRP-DDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
NGI V+++SP G + S+ D + IA ++ K+ T+IVL+Y +Q G + I
Sbjct: 184 SNNGIAVISYSPLGARNNIQPESLDVLSDCRIKEIARRYNKTPTEIVLKYNVQLGNIVI- 242
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
+ + E+ + FDF L+ EDM+ I TF+ E
Sbjct: 243 ----SDMLIESANFFDFYLAPEDMSYISTFSSE 271
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 157 bits (381), Expect = 2e-37
Identities = 78/179 (43%), Positives = 112/179 (62%), Gaps = 5/179 (2%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D VDY++TW+GMEE LGL +SIG+SNFN+ Q+ R+LE+ IKP + Q+E++++L Q K
Sbjct: 139 DEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKK 198
Query: 182 LIDYCKRNGIVVMAFSPFGP-----MFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYL 346
L ++C I V +SPFG +F + I P + IA+K+ K+ QIVLRY+
Sbjct: 199 LREFCASKSIAVTGYSPFGAPGRNNVFQPAGADISLQSPVITGIAKKYNKTNAQIVLRYV 258
Query: 347 IQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
I G +PIPKS + RI+ENID+FDF L+ E++ I + RT +D YPF
Sbjct: 259 IDIGAIPIPKSSSEKRIKENIDIFDFKLTPEEIAAIDKLDCGFRTCSAIEHKDCKEYPF 317
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 157 bits (381), Expect = 2e-37
Identities = 80/180 (44%), Positives = 111/180 (61%), Gaps = 6/180 (3%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQ 175
D VD+ DTW+ +EE K+ GL KSIG+SNFN Q++RIL +K P QVE +L+L Q
Sbjct: 140 DTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQ 199
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFH----DSLPSIRPDDPTLVAIAEKHGKSVTQIVLRY 343
KL+DYC+ IV++A+ G + D + +DP L +A+K+ +S I LRY
Sbjct: 200 RKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRY 259
Query: 344 LIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
LIQ+G+VP+ +S K+N + EN+ VF F LS EDM + NK R + F DHP YPF
Sbjct: 260 LIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAEFLVDHPEYPF 319
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 156 bits (378), Expect = 6e-37
Identities = 76/156 (48%), Positives = 107/156 (68%), Gaps = 1/156 (0%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+D L+TW GMEEAK LGLAKSIG+SNF+T +DR++ P+V Q+EV+ Q+KL+
Sbjct: 148 IDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLV 207
Query: 188 DYCKRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
GI VMA+SPFG + S + +D T+ IA K+ K+V Q+++RYL+++ ++
Sbjct: 208 ADSHERGIEVMAYSPFGFYVSRGSHNNPVKNDRTVADIARKYNKTVNQVLVRYLLERSLI 267
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
PIPKS + RI ENIDVFDF LS ED+N IG +K+
Sbjct: 268 PIPKSTNQQRIRENIDVFDFQLSPEDINAIGKLDKD 303
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 153 bits (370), Expect = 5e-36
Identities = 79/173 (45%), Positives = 110/173 (63%), Gaps = 1/173 (0%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
VDYLDTW+ ME+ +LGL +SIG+SNFN Q +R+L N +I+P V QVE + Q +L
Sbjct: 136 VDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLR 195
Query: 188 DYCKRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
++ KR+G+V+ A+ P P P D+ +A+K+G++ QI LRYL+Q GVV
Sbjct: 196 EHAKRHGLVICAYCPLARPQPARQWPPFLYDEHAQ-NLAKKYGRTTAQICLRYLVQLGVV 254
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
P+PKS K RIEEN VFDF LS +D+ + ++ +RTV S H YYPF
Sbjct: 255 PLPKSSNKARIEENFRVFDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPF 307
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 152 bits (369), Expect = 7e-36
Identities = 80/180 (44%), Positives = 111/180 (61%), Gaps = 7/180 (3%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DY+D W+GME K G KSIG+SNF QIDR+L +I P+V QVE++ +L Q LI
Sbjct: 110 IDYVDVWRGMEALKATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLI 169
Query: 188 DYCKRNGIVVMAFSPFG----PM-FH--DSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYL 346
DYCK I + A SPFG P+ F D P +DP +V +A KH ++ Q++LRY
Sbjct: 170 DYCKSKNIALTAHSPFGSPGRPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYH 229
Query: 347 IQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
IQ+ + IPKSVK + I EN +FDF L EDMN + + N+ R ++ + H +YPF+
Sbjct: 230 IQQDIAVIPKSVKPHHILENTKIFDFTLDEEDMNALKSLNRGWRACIITELEAHYFYPFK 289
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 151 bits (365), Expect = 2e-35
Identities = 74/175 (42%), Positives = 105/175 (60%), Gaps = 3/175 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY+DTW ME+ + GL ++IG+SNFN Q+ R+L+ +I P+ Q+E + +L Q K+
Sbjct: 142 DYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITT 201
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRP---DDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
+C GI+V A+SP G + + P DD T+ +A+KHGKS QI++RY IQ G
Sbjct: 202 FCAEKGIIVTAYSPLGSPARPWVKADDPVLMDDATVGQLAKKHGKSAAQILIRYQIQLGH 261
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
V IPKSV K RI N DVF F L +DM ++ + R S HP++PFE
Sbjct: 262 VVIPKSVTKERIASNFDVFSFQLDEDDMKQLAGLERNGRICPESSAFGHPHHPFE 316
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 150 bits (363), Expect = 4e-35
Identities = 77/178 (43%), Positives = 113/178 (63%), Gaps = 6/178 (3%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
VDYL+TWK E A+ G +SIG+SNF +QI R+ + ++KP+ LQVE++ + Q KL
Sbjct: 136 VDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLR 195
Query: 188 DYCKRNGIVVMAFSPFG----PMFH-DSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
++CK GIVV+ +SP G F D P++ ++ + IA+ HGK+ QI+LR+ +
Sbjct: 196 EFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNE-VVAGIAKAHGKTPAQIILRWFVD 254
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQ-DHPYYPF 523
G+ IPKSV RI EN+ VFDF L++E+++KI NK R V +S DHP+ PF
Sbjct: 255 SGLSAIPKSVTPQRISENLAVFDFQLTAEEISKIDGINKNWRIVDLSQRDGDHPHCPF 312
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 150 bits (363), Expect = 4e-35
Identities = 79/177 (44%), Positives = 112/177 (63%), Gaps = 6/177 (3%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKL 184
D++DTW ME+ + GL K+IG+SNFN QI+RIL +K P+V Q+E + +L Q+KL
Sbjct: 137 DFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKL 196
Query: 185 IDYCKRNGIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
I+YC GIVV A+SP G P PS+ +DP + AIA K+ K+ Q+++R+ IQ
Sbjct: 197 IEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLL-EDPRIKAIAAKYNKTTAQVLIRFPIQ 255
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
+ +V IPKSV RI EN+ VFDF +SSEDM + ++N+ R + H YPF
Sbjct: 256 RNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPF 312
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 149 bits (362), Expect = 5e-35
Identities = 75/179 (41%), Positives = 111/179 (62%), Gaps = 8/179 (4%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D++ WK MEE GLA++IG+SNFN QI RIL+N QIKP+ LQ+E +++L Q +L+
Sbjct: 139 DHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVK 198
Query: 191 YCKRNGIVVMAFSPFG-----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
+CK NGI V A+SP G + +P + D+P + IAEK GKS Q++LR+L+Q+
Sbjct: 199 FCKANGITVTAYSPLGSKGIEKLLGREVPDLL-DNPVVKDIAEKLGKSPAQVLLRHLLQR 257
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW---QDHPYYPF 523
G+ IPKS R+ +NID+F F + DM ++ ++ R F+ HP +PF
Sbjct: 258 GISTIPKSTNPTRLRDNIDLFGFEIDDSDMVRLNQLDQNIRICDFGFFPGITKHPEFPF 316
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 149 bits (360), Expect = 9e-35
Identities = 79/177 (44%), Positives = 109/177 (61%), Gaps = 6/177 (3%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLID 190
LDTW MEE + GL K+IGISNFN Q++ IL +K P+V Q+E + +L Q+KLI
Sbjct: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQ 198
Query: 191 YCKRNGIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
YC+ GIVV A+SP G P PS+ +DP + AIA KH K+ Q+++R+ +Q+
Sbjct: 199 YCQSKGIVVTAYSPLGSPDRPWAKPEDPSLL-EDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEK 529
+V IPKSV RI EN VFDF LSS+DM + ++N+ R + H YPF +
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHE 314
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 148 bits (358), Expect = 2e-34
Identities = 74/180 (41%), Positives = 110/180 (61%), Gaps = 6/180 (3%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQ 175
D D L TW+ +EE ++ GL KSIG+SNFN Q++ IL +K P Q+E + +L Q
Sbjct: 162 DQPDLLQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQ 221
Query: 176 DKLIDYCKRNGIVVMAF----SPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRY 343
+++++CK IVV+A+ SP + D I +DP L++I +K+ KS Q+ +RY
Sbjct: 222 KQMLEFCKSKDIVVVAYGVLGSPGAGKWVDQSCPILLEDPVLISIGQKYSKSPAQVSMRY 281
Query: 344 LIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
+IQ+G V I KS +R+++N++VFDF LS E+M I NK R S W+ HP YPF
Sbjct: 282 MIQRGCVAIAKSFNPDRMKQNLEVFDFQLSQEEMAAIDGLNKNMRYWSFSEWEKHPQYPF 341
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 147 bits (355), Expect = 3e-34
Identities = 71/179 (39%), Positives = 108/179 (60%), Gaps = 6/179 (3%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKL 184
D DTWK +E+ K+ GL +SIG+SNFN Q++ IL +K P QVE +++L Q KL
Sbjct: 144 DLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKL 203
Query: 185 IDYCKRNGIVVMAFSPFGPM----FHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
+++CK IV++ +S G + ++ + +DP L IA+KH ++ Q+ +RY +Q
Sbjct: 204 LEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAMRYHLQ 263
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEK 529
+GVV + KS RI++N VFDF L +EDM I N+ R + S W DHP YP+ +
Sbjct: 264 RGVVVLAKSFTPARIQQNFQVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPYSE 322
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 146 bits (353), Expect = 6e-34
Identities = 72/174 (41%), Positives = 109/174 (62%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D V L+TWK +EE + GL +SIG+SNFN Q+ I+ +G I+P V QVE ++ Q K
Sbjct: 128 DEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVK 187
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
L +C R GI++MA+SP G + D L +AEK+G+S QI LR+LI+ G
Sbjct: 188 LRKFCNREGILIMAYSPLGKP-KPGKKHVFLDSSDLNKMAEKYGRSPAQISLRFLIEIGT 246
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
+PIPKS K +R++EN+DV F L D+ + +F K++R++ + + + +YPF
Sbjct: 247 IPIPKSSKTDRMKENLDVLSFKLEETDVQALESFVKQQRSMTLDWLKSSKHYPF 300
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 143 bits (347), Expect = 3e-33
Identities = 77/178 (43%), Positives = 108/178 (60%), Gaps = 8/178 (4%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLI 187
+LD W+ MEE + GL K++G+SNFN QI+R+L +K P QVE + +L Q+KL
Sbjct: 138 FLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLT 197
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAI------AEKHGKSVTQIVLRYLI 349
YC GI + A+SP G PS +P+DP L+ I A KH K+ Q+++R+ I
Sbjct: 198 QYCHSKGITITAYSPLGS---PDRPSAKPEDPLLLEIPKIKEIAAKHKKTAAQVLIRFHI 254
Query: 350 QKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
++ VV IPKSV +RI+ENI VFDF LS EDM I +FN+ R G+ + +PF
Sbjct: 255 ERNVVVIPKSVTPSRIQENIQVFDFQLSEEDMAAILSFNRNWRACGLFAASHNEDFPF 312
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 143 bits (346), Expect = 4e-33
Identities = 74/181 (40%), Positives = 109/181 (60%), Gaps = 7/181 (3%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQ 175
D VD DTW+ ME+ K+ GLAKSIG+SNFN Q++ IL +K P QVE +L+L Q
Sbjct: 140 DTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQ 199
Query: 176 DKLIDYCKRNGIVVMAFSPFGPM-----FHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLR 340
KL+ YCK N IV++A+ G ++ P + DDP L A+A+K+ ++ I LR
Sbjct: 200 SKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLL-DDPVLCAMAKKYKRTPALIALR 258
Query: 341 YLIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYP 520
Y + +G+V + KS + RI EN+ VFDF L+S+DM + ++ R ++ HP +P
Sbjct: 259 YQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGLDRNLRYFPADMFKAHPNFP 318
Query: 521 F 523
F
Sbjct: 319 F 319
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 142 bits (344), Expect = 7e-33
Identities = 73/175 (41%), Positives = 106/175 (60%), Gaps = 2/175 (1%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLG-LAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKL 184
VDY++TWK ME+ G +SIG+SNFN+ QI+RIL+ +KP QVE N Q KL
Sbjct: 143 VDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKL 202
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRP-DDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
I +C+ GI V A+ P G + + DDP ++ I K+GK+ Q++LRYLI G
Sbjct: 203 IAFCQARGITVTAYGPMGRPHRTTNGNRNALDDPKVLEIGRKYGKTGGQVILRYLIDIGT 262
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
+PIP S + R+ +NIDV DF L+ E++ + +F+ RT+ + H YYPF+
Sbjct: 263 IPIPYSTNEERMRQNIDVCDFKLTGEEIEYLASFH-SARTIPFLPLKSHKYYPFD 316
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 141 bits (341), Expect = 2e-32
Identities = 72/173 (41%), Positives = 106/173 (61%), Gaps = 6/173 (3%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLIDYC 196
TW+ ME K+ GL KS+G+SNFN Q++ IL +K P QVE + + Q KL+ +C
Sbjct: 150 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 209
Query: 197 KRNGIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
+++ IV+ A+SP G P++ + D L ++ +++ K+ QIVLR+ IQ+GVV
Sbjct: 210 QQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVV 269
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
IPKS RI+EN +FDF+L+ E+M I NK R V + W+DHP YPF
Sbjct: 270 VIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 141 bits (341), Expect = 2e-32
Identities = 74/186 (39%), Positives = 114/186 (61%), Gaps = 12/186 (6%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D Y +TWK +E GL +++G+SNFN+ QID IL ++P+VLQVE + +L Q++
Sbjct: 136 DSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNE 195
Query: 182 LIDYCKRNGIVVMAFSPFGP---MFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
LI +C+ G+ V A+SP G + D + ++P ++A+AEK+G+S QI+LR+ +Q
Sbjct: 196 LIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQ 255
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV-------GMSFWQD-- 505
+ V+ IPKS+ +RI +NI VFDF S E+M ++ NK R + G +D
Sbjct: 256 RKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAG 315
Query: 506 HPYYPF 523
HP YPF
Sbjct: 316 HPLYPF 321
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 140 bits (338), Expect = 4e-32
Identities = 67/156 (42%), Positives = 104/156 (66%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+DTW+ +E+ G AK+IG+SNF+ + R+LE G + P+V Q+E++ L Q+ + +
Sbjct: 115 YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAF 174
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C++NGIVV A+SP D+L DP + IA +HGK+ Q+VLR+ +Q ++ IP
Sbjct: 175 CQKNGIVVEAWSPL-MKGRDALT-----DPVITDIAARHGKTPAQVVLRWHLQHDIIAIP 228
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
KSV +RI+EN+D+FDF LS +DM +I N+ +RT
Sbjct: 229 KSVTPSRIQENLDIFDFVLSPDDMRQIDQLNRNERT 264
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 138 bits (333), Expect = 2e-31
Identities = 70/155 (45%), Positives = 99/155 (63%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y DTW+ +E+ G ++IG+SNF ++ +L++ +IKP V QVE + L Q +L DY
Sbjct: 119 YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDY 178
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
CK GI + A+SP + D+ L IAEKH KSV Q++LR+ +Q VV IP
Sbjct: 179 CKAQGIQLEAWSPL-------MQGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHEVVTIP 231
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS+K++RI EN D+FDF LS EDM+KI NK++R
Sbjct: 232 KSIKEHRIIENADIFDFELSQEDMDKIDALNKDER 266
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 137 bits (332), Expect = 2e-31
Identities = 69/178 (38%), Positives = 108/178 (60%), Gaps = 1/178 (0%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+D + W+ ME + GL KSIG+SNF QI++I++ +IKP + QVE+N++L Q+KL
Sbjct: 130 MDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLR 189
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+ CK IVV A+ P G + DD +V++A+K+ K+ QI LR+L+Q G++
Sbjct: 190 EVCKSYNIVVEAYRPIGGKPANESDKNCLDDEVVVSLAKKYNKTTAQICLRWLVQNGIIA 249
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGM-SFWQDHPYYPFEKSDQ 538
+PKS NR+ +N VF+++LS+EDM + N KR V ++W Y F +Q
Sbjct: 250 VPKSTNPNRLLQNYQVFEWSLSNEDMKALEKRNLNKRNVKFENYWNGKTYEEFWGEEQ 307
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 136 bits (330), Expect = 4e-31
Identities = 68/184 (36%), Positives = 109/184 (59%), Gaps = 6/184 (3%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSV-LQVEVNLHLGQD 178
D +DY+DTW+ ME + GL ++IG+SNF QI R+L+ P +QVE + L Q+
Sbjct: 138 DTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQN 197
Query: 179 KLIDYCKRNGIVVMAFSPFGP-----MFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRY 343
+LI++CK+ GI V A+SP G + + +DP + AIA+K G S Q+++RY
Sbjct: 198 ELIEFCKKQGITVTAYSPLGSPERVLQKRATTDPLLMEDPVVCAIAKKKGVSPAQVLIRY 257
Query: 344 LIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
+Q+GV +PKSV +RI++N + +F LS E+ + NK R + + ++ YYPF
Sbjct: 258 QLQRGVAVLPKSVMPSRIQQNFEALNFELSKEEFQALVNLNKNYRLLNFAPMKNMKYYPF 317
Query: 524 EKSD 535
++
Sbjct: 318 NDNN 321
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 135 bits (327), Expect = 9e-31
Identities = 75/188 (39%), Positives = 110/188 (58%), Gaps = 14/188 (7%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D + WK ME+ G KSIG+SNFN TQI IL+ +IKPS LQVEV+ + Q LI+
Sbjct: 165 DPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIE 224
Query: 191 YCKRNGIVVMAFSPFG-PMFHDSL-PSIRPDD-------PTLVAIAEKHGKSVTQIVLRY 343
+C++NGI+V ++P G P L P ++ P + IA+KHGKSV QI+L +
Sbjct: 225 FCQKNGIIVTGYAPLGSPGARKELHPGQMEEEFPDVFKLPVVNEIAKKHGKSVVQILLHH 284
Query: 344 LIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSF-----WQDH 508
L+QKG+ I S N ++ENI++FDF L+ ++M + +K +R + + H
Sbjct: 285 LVQKGIAVIFSSKNPNHLKENIEIFDFELTEDEMKSLDALDKGERGKIFDYKFLKGIEKH 344
Query: 509 PYYPFEKS 532
YYPF +
Sbjct: 345 QYYPFSSA 352
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 134 bits (324), Expect = 2e-30
Identities = 74/194 (38%), Positives = 113/194 (58%), Gaps = 20/194 (10%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V YL+TW ME+ G KS+G+SNFN+ Q+D +L++ + PSVLQVE + L Q +L+
Sbjct: 138 VHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELL 197
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRP---DDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
++C+ +VV A+SP G S P DDP L+ IA++ KS+ Q+ +R+ +Q+G
Sbjct: 198 NFCRERSVVVSAYSPLGCGDRAWKLSGEPSIFDDPGLLKIAQRLRKSIAQVAIRFQVQRG 257
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV---------------GMS 493
+ IPKS + I+ENI+VFDF LS +DM + + + + V G+
Sbjct: 258 IPVIPKSATPSHIQENINVFDFELSEDDMALLSSLPRRRILVPPKKDKDNKPMVDSDGLV 317
Query: 494 FWQD--HPYYPFEK 529
+D HPYYPF +
Sbjct: 318 IPRDGSHPYYPFHE 331
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 134 bits (323), Expect = 3e-30
Identities = 69/177 (38%), Positives = 106/177 (59%), Gaps = 4/177 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DYLDTWK ME+ + GL +IG+SNFN QI+R+L ++KP +LQ+E + +L Q LI
Sbjct: 138 IDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLI 197
Query: 188 DYCKRNGIVVMAFSPFGPMFHD-SLPSIRP--DDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
C N I V A+S G P P +P +V++AEK+G++ Q++LRY Q G
Sbjct: 198 TLCYDNAIGVTAYSSLGSGHTPYEKPGSYPLLQNPIIVSVAEKYGRTPAQVLLRYQTQSG 257
Query: 359 VVPIPKSVKKNRIEENID-VFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
++ IP+SV K + +N ++DF L+ +D+ I + R + M HP++PFE
Sbjct: 258 IIVIPRSVSKQHMHDNFKRIWDFQLAIDDVKAIDGLDCNGRFMTMKAAYGHPHHPFE 314
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 132 bits (319), Expect = 8e-30
Identities = 70/185 (37%), Positives = 109/185 (58%), Gaps = 4/185 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DY+DTW+ ME + GL ++IG+SNFN Q++R+L ++KP VLQ+E + +L Q LI
Sbjct: 139 IDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLI 198
Query: 188 DYCKRNGIVVMAFSPFGPMFHD-SLPSIRP--DDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
C N I V A+S G P P PT++AIAEK+ ++ Q++LR+ Q G
Sbjct: 199 TLCYDNAIAVTAYSCLGSGHTPYEKPGAYPLLQHPTILAIAEKYERTAAQVLLRFQTQSG 258
Query: 359 VVPIPKSVKKNRIEENID-VFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSD 535
++ IP+SV K + +N ++DF L+ +D+ I + R + M HP++PFE
Sbjct: 259 IIVIPRSVSKQHMLDNFKRIWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFEPKA 318
Query: 536 QVHDN 550
+V DN
Sbjct: 319 KV-DN 322
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 132 bits (319), Expect = 8e-30
Identities = 68/173 (39%), Positives = 104/173 (60%), Gaps = 2/173 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG--QIKPSVLQVEVNLHLGQDKL 184
D+LDTW+ ME+ GL K+IG+SNFN Q++R+L + KP Q+E + +L Q L
Sbjct: 147 DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNL 206
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
I +C+ + V A+ P G + + I D+P + IA++HGKS QI++R+ IQ+ V+
Sbjct: 207 ISFCQSRDVSVTAYRPLGGSC-EGVDLI--DNPVIKRIAKEHGKSPAQILIRFQIQRNVI 263
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
IP S+ + I+ENI VFDF L+ DM+ I + N+ R ++H YPF
Sbjct: 264 VIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYPF 316
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 131 bits (316), Expect = 2e-29
Identities = 76/179 (42%), Positives = 107/179 (59%), Gaps = 11/179 (6%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D VD+ WK ME G AKSIG+SNFN +Q+ I N +IKPS LQVE + +L Q +
Sbjct: 155 DDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQ 214
Query: 182 LIDYCKRNGIVVMAFSPFGP-----MFHDSLPSIRP---DDPTLVAIAEKHGKSVTQIVL 337
L +CK + IV+ A++P G H P P + P + ++A K+ KS QI+L
Sbjct: 215 LRKFCKEHNIVMTAYAPLGSHNARLNLHRGTPKELPALVELPLIKSLAAKYNKSPGQILL 274
Query: 338 RYLIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK-EKRTV--GMSFWQD 505
R+ IQ+G+V IPKS R + NID+FDF L+ E+M KI +K EK V ++F++D
Sbjct: 275 RHTIQEGLVAIPKSSNAQRQKSNIDIFDFKLTDEEMKKIDALDKGEKGRVFDFLAFYKD 333
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 131 bits (316), Expect = 2e-29
Identities = 67/182 (36%), Positives = 113/182 (62%), Gaps = 11/182 (6%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
++++ W ME+ G K+IG+SNFN +QI RIL+N ++K S+LQ+E++++ Q +L+
Sbjct: 140 NHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVK 199
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPD------DPTLVAIAEKHGKSVTQIVLRYLIQ 352
+CK+ I + A+SP G L + + + ++ IA+K+ KS QI+LRY++Q
Sbjct: 200 FCKQENIPITAYSPLGSRSLIKLLNKTEEISDMLQNDVVMEIAKKYKKSSAQILLRYIVQ 259
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK--EKRTVGMSFW---QDHPYY 517
G+V IPKS+ RI+ENI +FD+ ++ EDM K+ ++ R + F+ + HP Y
Sbjct: 260 NGIVVIPKSINPQRIKENIQLFDWEINPEDMKKLYNLDRGESSRICDLKFFKGIETHPEY 319
Query: 518 PF 523
PF
Sbjct: 320 PF 321
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 131 bits (316), Expect = 2e-29
Identities = 67/179 (37%), Positives = 114/179 (63%), Gaps = 7/179 (3%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
VDYL+TWK +E+A G +SIG++NFN Q++++ G IKP+VLQVE+N L Q+++
Sbjct: 143 VDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIR 202
Query: 188 DYCKRNGIVVMAF----SPFGPMF--HDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLI 349
+C+ GI++ AF +P ++ H+ P++ ++ TL +IA+ HGKSV Q+++R+ I
Sbjct: 203 QFCREKGIILTAFMLTGNPGSALYRKHED-PNLLYNE-TLQSIAKGHGKSVVQVLVRWAI 260
Query: 350 QKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQ-DHPYYPF 523
+ KS + RI +NI++F F L+S+++ +I N + R + DHPY+P+
Sbjct: 261 DLRTTALVKSSESKRIRQNINIFKFRLTSQEIARIKALNIDFRILNPLLGNYDHPYFPW 319
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 129 bits (311), Expect = 7e-29
Identities = 67/164 (40%), Positives = 99/164 (60%), Gaps = 5/164 (3%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQ 175
D +LDTW+ MEE + GLAK+IGISNFN QI+ +L +K P+ Q+E + HL Q
Sbjct: 158 DGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQ 217
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRP---DDPTLVAIAEKHGKSVTQIVLRYL 346
+KLI +C+ GI V AF+ G + P DDP + AIA K+ + Q+++++
Sbjct: 218 EKLIHFCRSRGISVTAFACLGSADRSWASADEPSFLDDPQINAIARKNQMTPAQVLIKFQ 277
Query: 347 IQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
IQ+ + + KSV +RI+ENI FD+ LS +DM + +FN R
Sbjct: 278 IQRNITAVVKSVSPHRIKENIKAFDYELSDDDMKTLMSFNSNWR 321
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 129 bits (311), Expect = 7e-29
Identities = 68/176 (38%), Positives = 100/176 (56%), Gaps = 1/176 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D+ W+ MEE LGLAK+IG+SNF T +D++L I P+V QVE+N Q + +
Sbjct: 142 DFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVRE 201
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
YC GI V A+SP G + + P L IA GKS+ Q+ LR++ ++GV PI
Sbjct: 202 YCAAKGIRVAAYSPLGGQNWIGEGNDVMESPVLADIARARGKSIAQVSLRWIHEQGVTPI 261
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK-RTVGMSFWQDHPYYPFEKSD 535
PKS K R+++N+++FD+ L+ ED KI ++K T F D + + SD
Sbjct: 262 PKSYNKERLKQNLEIFDWELTKEDRLKISQIPQKKIVTAARMFSPDGEFASVDLSD 317
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 129 bits (311), Expect = 7e-29
Identities = 64/159 (40%), Positives = 96/159 (60%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+ MEE + LGL K+IG+SNF+ ++ +L I+P V QVE+NL Q KL +
Sbjct: 144 DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLRE 203
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+CK NGI+V AFSP + +D L IAE HGKS+ Q+ LR+L ++GV +
Sbjct: 204 FCKENGIIVTAFSPLRKGASRGPNEVMEND-VLKEIAEAHGKSIAQVSLRWLYEQGVTFV 262
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
PKS K R+ +N+ +FD+ L+ +D +KI ++ + G
Sbjct: 263 PKSYDKERMNQNLHIFDWALTEQDHHKISQISQSRLISG 301
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 125 bits (302), Expect = 9e-28
Identities = 66/177 (37%), Positives = 105/177 (59%), Gaps = 7/177 (3%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
++ ME+ G K+IG+SNF+ + R++E I+P+ LQVE++ L Q+KLI++CK +
Sbjct: 100 YQAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEH 159
Query: 206 GIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ V A+SP G P D P + +DP + IA K GKS QI++R+ +++G++ IP
Sbjct: 160 NMTVTAYSPLGAPDRPWVKDDDPKLM-EDPIVTGIATKKGKSPAQILIRFCLERGIICIP 218
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF---EKSD 535
KSV +RI+ N + +F L ED+ + N R + W +HP +PF EK D
Sbjct: 219 KSVTPSRIQANFEALNFELDPEDLKTLLAMNIGYRGCLLD-WVNHPQHPFLGPEKDD 274
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 125 bits (302), Expect = 9e-28
Identities = 68/173 (39%), Positives = 102/173 (58%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V +TW+ ME+ LGL KSIG+SNFN + +L +IKP V QVE++ +L Q KL
Sbjct: 154 VSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQ 213
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+YC + I ++A+SP G D + L +IA K+ KSV ++ ++L Q+G+
Sbjct: 214 EYCDKYEIKLVAYSPLGQGKCDFF-----SNKILKSIAGKYKKSVANVIFKWLNQRGIAA 268
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
IPKS +RI EN ++FDF LS++D+ KI + N RT + P+Y F+
Sbjct: 269 IPKSGNHSRIIENFNIFDFQLSNDDIEKINSLNANIRTCSPITFFGTPFYLFD 321
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 124 bits (300), Expect = 2e-27
Identities = 66/179 (36%), Positives = 106/179 (59%), Gaps = 12/179 (6%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W ME GL KSIG+SNF+ Q+ R+L+N +I+P+ Q+E +++L Q L+D+CK
Sbjct: 146 WVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSE 205
Query: 206 GIVVMAFSPFG----PMFHDSLPSIRP-----DDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
I V A+SP G F+ +R D P + IA HGK+ Q++LR++I G
Sbjct: 206 NITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTG 265
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW---QDHPYYPFE 526
V IPKS R+++N+DVFDF L++E++ K+ + ++ R +F+ + HP + F+
Sbjct: 266 VSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFK 324
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 124 bits (298), Expect = 3e-27
Identities = 65/177 (36%), Positives = 104/177 (58%), Gaps = 11/177 (6%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W+ ME G K+IG+SNFN Q+ RI++ Q++P+VLQVEV++++ Q L +C ++
Sbjct: 156 WRAMEAQLAAGKTKNIGLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQH 215
Query: 206 GIVVMAFSPFGPMFHDSLPSIRP-------DDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
IVV AF P G F + RP +DP ++ +A H K+ Q++LRYL Q V+
Sbjct: 216 DIVVCAFCPLGGPFRLIRKASRPGEVKLLLEDPQVLDVATAHHKTPAQVLLRYLHQINVI 275
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK-EKRTVGMSFWQ---DHPYYPF 523
PIPKS R+ +N +FDF L+S +M+++ ++ + + F + HP +PF
Sbjct: 276 PIPKSANPTRLFQNTQIFDFELTSAEMSRLAGLDRGHEGRIFTEFRRGDHTHPEFPF 332
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 124 bits (298), Expect = 3e-27
Identities = 65/172 (37%), Positives = 98/172 (56%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++TW+ E+ + ++IG+SNF +D +L N + P V QVE++ H Q L Y
Sbjct: 118 YIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAY 177
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C I V A+ P G +P LV +AEKH +S Q+++R+LIQ GV+ IP
Sbjct: 178 CAEKNIAVTAWRPLGK-------GALLTEPQLVELAEKHKRSAAQVIIRWLIQLGVIAIP 230
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEK 529
KS + RI++N DVFDF LS EDM +I + ++ R +G S ++P E+
Sbjct: 231 KSSHEERIKQNFDVFDFELSPEDMRRIESMDRNSR-IGSS---PETFFPTER 278
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 123 bits (297), Expect = 4e-27
Identities = 64/156 (41%), Positives = 97/156 (62%), Gaps = 3/156 (1%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TW+GME+ +LGL +SIG+SN+ L +IKP+V Q E + + +D L+ +C +
Sbjct: 142 TWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMK 201
Query: 203 NGIVVMAFSPFGPMF--HDSLPSIRP-DDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+G++ A +P G D S+ P DDP L +A+K+GKSV QI LR+ IQ+ IP
Sbjct: 202 HGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTAVIP 261
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
KS K R++EN++V +F LS EDM I + +++ RT
Sbjct: 262 KSSKIQRLKENLEVLEFQLSDEDMQLIYSIDRKYRT 297
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 123 bits (296), Expect = 5e-27
Identities = 62/183 (33%), Positives = 105/183 (57%), Gaps = 7/183 (3%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+ ++DTW+ +E+ G K++G+SNF+ Q+ + + ++KP+ QVE +++ Q +L
Sbjct: 139 IAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKPANQQVECHIYWPQQELR 198
Query: 188 DYCKRNGIVVMAFSPFG-PMFHDSLPS-IRPD-----DPTLVAIAEKHGKSVTQIVLRYL 346
CK+ G+ V A++P G P + P + P+ +P + +A K+ K+ QI++R+L
Sbjct: 199 ALCKKLGVTVTAYAPLGSPGRKAARPDGVWPEGDPLLEPIVKQLAAKYHKTAAQILIRHL 258
Query: 347 IQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFE 526
Q G+ IPKSV +RI ENI FDF LS EDM+ + + R F HP++P +
Sbjct: 259 TQHGISTIPKSVSPDRIVENISTFDFKLSDEDMHTLNSIETRTRLFIADFAVKHPFFPHD 318
Query: 527 KSD 535
D
Sbjct: 319 DID 321
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 122 bits (295), Expect = 6e-27
Identities = 62/155 (40%), Positives = 100/155 (64%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
+D+WK +E+ + L K+IG+SN+ + +L+N QI P+V QVE + L Q L++YC
Sbjct: 123 MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYC 182
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
K++ I + A+SP H + +DPT+ IA+K+ K+ QI++R+ I++ +V IPK
Sbjct: 183 KKHKIQLEAYSPLA---HGQ----KIEDPTIAKIAQKYDKTPAQILIRWAIEQKIVVIPK 235
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
S+KK RI EN VFDF +S EDM + + +++ RT
Sbjct: 236 SIKKERIIENSKVFDFAISEEDMKILNSLDEDFRT 270
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 122 bits (294), Expect = 9e-27
Identities = 62/167 (37%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
+I+ +TW+ ME+ GL KSIG+SNFN +++ +L +I+P+V Q E +++ + K
Sbjct: 126 EIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPK 185
Query: 182 LIDYCKRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
L +CK++ I + + P G P +P+ ++ + AIA+KH K QI +++ I G
Sbjct: 186 LHQFCKKHNIHITGYCPLGNPGISSGVPA-PFENEVVKAIAKKHNKKAAQICIKFSIASG 244
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
IPKSV + RI+EN +VFDF L EDM K+ +K + MSF+
Sbjct: 245 HSVIPKSVHEERIKENGEVFDFELDEEDMEKLRGLDKNIKVCDMSFY 291
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 122 bits (294), Expect = 9e-27
Identities = 61/166 (36%), Positives = 96/166 (57%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+ MEE GL KS+G++NF + +L +IKP+V Q+E++ +L Q+ L+ +C
Sbjct: 139 ETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCY 198
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
I V A+SPFG P + DPT+ +A+ GK+ Q++LR+ +Q+ IP+S
Sbjct: 199 SQNIAVTAYSPFG---STEAPVL--TDPTVKEVAKGLGKTPAQVLLRWAVQRNTSVIPRS 253
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYY 517
RI+EN ++ F LS+E M + T N+ KR V W PY+
Sbjct: 254 SNATRIKENFEIATFELSNEHMAALNTLNRNKRFVNPIEWWGFPYF 299
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 120 bits (290), Expect = 3e-26
Identities = 65/151 (43%), Positives = 95/151 (62%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+DTWK + + K GLA+SIG+SNF + R+ + I P V QVE++ L Q +L +
Sbjct: 173 YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAF 232
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
++ IV A+SP G +L + DP L IA+KHG+S Q+++R+ IQ+G+V IP
Sbjct: 233 HAKHRIVTEAWSPLG---QGTLLA----DPVLAGIAQKHGRSAAQVIIRWHIQQGLVVIP 285
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
KSV +RI EN +VFDF L +EDM I + +
Sbjct: 286 KSVTPSRIAENANVFDFTLDAEDMAAIASLD 316
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 119 bits (287), Expect = 6e-26
Identities = 60/174 (34%), Positives = 99/174 (56%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D + + W G+E+ GL +SIG+SNFN QI+ +L + I P+V Q+E ++ Q
Sbjct: 139 DSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRP 198
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
+ +C++ I+VM ++P G LP ++ + L IA K+ Q+ LRYLI +GV
Sbjct: 199 MRKFCQQQNILVMGYTPLG---KQKLPFLQ--NNRLKEIALSVDKTTAQVSLRYLIDEGV 253
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPF 523
VPI KS + R +EN+D+FDF L+ + + ++ ++R M F ++PF
Sbjct: 254 VPIVKSTDRKRQQENLDIFDFKLTKQQLEELDAIGGDQRACKMDFLAGAKHFPF 307
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 119 bits (286), Expect = 8e-26
Identities = 60/183 (32%), Positives = 104/183 (56%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DY W+ MEE + LGL K+IG+SNF+ ++ +L N ++ P+V QVEVN Q +L
Sbjct: 141 MDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLT 200
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
++CK NGI+V+A++ G + + L IA G +V Q+ LR+ ++G+
Sbjct: 201 EFCKSNGILVVAYAALGAVGTFYGTNRVMGSEVLNEIARIRGNTVAQVCLRWAYEQGIGV 260
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSDQVHD 547
+ KS K R+E+N+ +F++ LS ++ KI + + +G + H PF+ +++ D
Sbjct: 261 LVKSFNKERMEQNLQIFNWTLSDDESKKISEIPQGRACLGTDYTSVHG--PFKTIEELWD 318
Query: 548 NPF 556
F
Sbjct: 319 GEF 321
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 118 bits (285), Expect = 1e-25
Identities = 62/159 (38%), Positives = 93/159 (58%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D TWK MEE LGLAKSIGI N+ T ++ ++LE I P+V QVE+N Q L +
Sbjct: 143 DIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLRE 202
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+CK+ GI V A+SP G ++ L IA GK++ Q+ LR++ Q+G +
Sbjct: 203 FCKQKGIHVSAWSPLGAYKIFWGSGAVMENQILQDIATAKGKTIAQVALRWVYQQGSSAM 262
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
KS K R+++N+++FDF LS E++ KI + ++ G
Sbjct: 263 AKSFNKERMKQNLEIFDFELSEEELEKIKQIPQRRQYTG 301
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 118 bits (285), Expect = 1e-25
Identities = 59/169 (34%), Positives = 101/169 (59%), Gaps = 1/169 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+GMEE LGLA++IG+SNF+ +++++L ++P+ QVE+N Q L +
Sbjct: 144 DMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLRE 203
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
C+R G+ + +SP G + D L IA+ GK++ QI LR++ ++G V +
Sbjct: 204 VCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLL 263
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDH-PY 514
K+ +NR++EN+D+FD+ L+ E+ +KI +++ GM F D+ PY
Sbjct: 264 VKTYNENRMKENLDIFDWELTEEERDKISKLPQQRGLTGMQFVCDNGPY 312
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 118 bits (284), Expect = 1e-25
Identities = 61/165 (36%), Positives = 95/165 (57%), Gaps = 5/165 (3%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+ ME ++ GL K IG+SNF ++ +++ + + KP V QVE + L Q LI+YC
Sbjct: 156 ETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCA 215
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRP-----DDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
I++ A+SP G M ++ D P + AIAE G S Q+VL + +Q+G+
Sbjct: 216 SEEILITAYSPLGSMDRPQSLKVKDAPAVLDHPVIRAIAETRGCSPAQVVLAWDVQRGIS 275
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
IPKSVK +R+ EN+ D LS+ ++ KI ++ R V +FW
Sbjct: 276 AIPKSVKPSRLLENLQAADIQLSNTELQKIEALDQNFRLVNGAFW 320
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 118 bits (283), Expect = 2e-25
Identities = 62/172 (36%), Positives = 101/172 (58%), Gaps = 5/172 (2%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+ W+ +EE LG+ +SIG++NFN + +L +IKP V Q+EV +L Q LI++ K
Sbjct: 149 EVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLINFLK 208
Query: 200 RNGIVVMAFSPFGPM--FHDSLPSIRP---DDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
R I +A SP G F ++ ++ ++ IA+KH KSV Q++LR L+Q+ ++
Sbjct: 209 RCKIETVAISPLGRAGCFENTPEGMKIKLLEEDIFKQIAQKHKKSVVQVILRCLVQREIM 268
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYP 520
IPK+ K +R++EN ++FDF L+ EDM +I + R + + Q Y P
Sbjct: 269 MIPKTAKLDRLKENSEIFDFELTEEDMKQIYSLENGTRAINLKHSQWFGYVP 320
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 117 bits (282), Expect = 2e-25
Identities = 63/185 (34%), Positives = 103/185 (55%), Gaps = 14/185 (7%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D++ W+ ME+ G +SIG+SNFN +Q+ + E+ +IKPS LQ+E+ + Q + +
Sbjct: 162 DHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRE 221
Query: 191 YCKRNGIVVMAFSPFG---------PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRY 343
C I V AFS G + SLP++ D P + IAE H ++ Q++LR+
Sbjct: 222 LCAERNITVTAFSTLGSPGSSPDKKTRYIKSLPTLF-DHPIVKKIAEAHNRTSAQVLLRH 280
Query: 344 LIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQD-----H 508
+Q G++ +PKS RI++NI +FDF L+ ++M + +K ++ F+ D H
Sbjct: 281 AVQNGIIVLPKSTNPGRIKQNIGIFDFALTEDEMQAMNGLDKGEKGRIFHFFIDKGVEKH 340
Query: 509 PYYPF 523
P YPF
Sbjct: 341 PQYPF 345
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 117 bits (282), Expect = 2e-25
Identities = 60/147 (40%), Positives = 93/147 (63%), Gaps = 2/147 (1%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
DTW+ MEE + G KS+G+SNF ++ + + ++ PSV Q+E + Q ++ ++CK
Sbjct: 123 DTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCK 182
Query: 200 RNGIVVMAFSPF--GPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+GI V ++SP G +F + L L+ +++K+ KSV+Q+ LR++IQ V+ IP
Sbjct: 183 NHGIAVESWSPLARGKVFGNDL---------LIGLSKKYQKSVSQVCLRWIIQHDVIAIP 233
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
KS RI+ENIDVFDF LS E+M KI
Sbjct: 234 KSSSPERIKENIDVFDFELSKEEMKKI 260
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 116 bits (279), Expect = 6e-25
Identities = 60/156 (38%), Positives = 89/156 (57%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
+ DTW+ +E+ K G KSIG+SN+ ++ + + P V QVE + +L Q L DY
Sbjct: 120 FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADY 179
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ + IV A+SP G + DDP L +A H KSV Q++LR+ +Q +V IP
Sbjct: 180 DQEHDIVTEAWSPLGRR-------VVLDDPMLAKMAAHHNKSVAQVILRWELQHQLVTIP 232
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
KS RI+EN ++FDF+L ++M I NK +RT
Sbjct: 233 KSTHPERIQENANIFDFSLDIDEMTMIDLLNKNERT 268
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 116 bits (279), Expect = 6e-25
Identities = 60/173 (34%), Positives = 99/173 (57%), Gaps = 1/173 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+GMEE LGLA++IG+SNF+ +++++L ++P+V QVEVN Q L +
Sbjct: 142 DMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLRE 201
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
C+R G+ + +SP G + D L IA GK++ QI LR+L ++G V +
Sbjct: 202 VCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLL 261
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDH-PYYPFE 526
K+ + R++EN+D+F++ L+ E+ +I + + G+ F DH PY E
Sbjct: 262 VKTYNEKRMKENLDIFNWELTDEERERISQLPQLRGLPGLEFISDHGPYKSVE 314
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 116 bits (278), Expect = 7e-25
Identities = 57/149 (38%), Positives = 95/149 (63%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
DTW+ MEEA A++IG+SNF +D +L+ ++ P+V Q+ +N +D+++ Y +
Sbjct: 131 DTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNR 190
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
++ I+ A+SP G S+P ++ +A+K+ KSV Q+VLR+ +Q G +P+PKS
Sbjct: 191 KHDILSEAYSPLGTGKIFSIPELK-------TLADKYDKSVAQVVLRWSLQHGFLPLPKS 243
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
V +RIE+N ++FDF LS +DM I F+
Sbjct: 244 VHADRIEQNTELFDFELSDDDMKVIDGFH 272
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 116 bits (278), Expect = 7e-25
Identities = 56/153 (36%), Positives = 92/153 (60%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
+DTW +E A G ++IGISNFN+ Q ++ ++P V Q+E +L L Q K+ ++
Sbjct: 111 IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFL 170
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
++ IV ++SP G + + +P L I+EK+GKS Q++LRYL+Q VV IP+
Sbjct: 171 EKENIVHESYSPLGNGQQNLI-----SNPVLKEISEKYGKSPIQVILRYLVQNDVVTIPR 225
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
S I+ NID+FDF L ++D+ ++ ++ K
Sbjct: 226 STNPAHIKSNIDIFDFELDNDDLKRLRVLDERK 258
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 116 bits (278), Expect = 7e-25
Identities = 57/155 (36%), Positives = 96/155 (61%), Gaps = 2/155 (1%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
+W+ M E + GL +SIG+SNFN ++ + ++ I P V Q+EV+ +L ++L+D+C++
Sbjct: 119 SWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRK 178
Query: 203 NGIVVMAFSPF--GPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
+ I + A+SP G H DP L ++ +K+GK+ Q++LR+ +QKG + I K
Sbjct: 179 HSIAIQAYSPLTRGEKLH---------DPLLRSLGDKYGKTPAQVLLRWSLQKGYICISK 229
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
SV+ +RI EN+DVF+F +S DM + + RT
Sbjct: 230 SVQLSRIIENVDVFNFTISMADMEILDGLEENLRT 264
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 116 bits (278), Expect = 7e-25
Identities = 59/148 (39%), Positives = 93/148 (62%), Gaps = 2/148 (1%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL--ENGQIKPSVLQVEVNLHLGQDKLID 190
++TWK ++EA + G+ KSIG+SNF I + E + KP V Q+E++ L + L+D
Sbjct: 128 IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVD 187
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
YC+ GIV+ A+ P + +DPTLV +A+K+ K+ Q++LR+ I +GVV I
Sbjct: 188 YCQNLGIVLEAYCPL-------TTGAKLNDPTLVKLAKKYNKTPAQVLLRWNIDRGVVVI 240
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
PKS+K R+ +N D+FDF L+ ED ++
Sbjct: 241 PKSLKPERLPQNFDLFDFKLTDEDFAEL 268
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 115 bits (277), Expect = 1e-24
Identities = 57/153 (37%), Positives = 92/153 (60%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D++ TWK +EEA+ G +SIG+SNF + R+ + + P+V Q+EV+ + G +++
Sbjct: 126 DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQIEVHPYFGNEEVRR 185
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+C + I V A+SP DDPT+ A+A + GKS Q+VLR+ +++G +
Sbjct: 186 HCGEHQIGVEAWSPIAQ-------GKVLDDPTVTAVANRLGKSPAQVVLRWHVERGDIVF 238
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
PKSV +R+EEN +FDF L+ ED+ I +K
Sbjct: 239 PKSVTPSRMEENFALFDFELTEEDLALISALDK 271
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 115 bits (277), Expect = 1e-24
Identities = 54/155 (34%), Positives = 93/155 (60%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
L+TWK + E + G+ K IG+SNFN + ++E + KP + Q E++ K I++C
Sbjct: 139 LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFC 198
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
++NGI+V A+SP H+ + P + +A+K+ K+V Q++LR+ +Q +V IPK
Sbjct: 199 QKNGILVEAYSPLARQ-HEKVMK----HPLINQLAQKYKKTVAQVILRWALQNNMVIIPK 253
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
S RI+ENID+ DF LS +++ ++ ++ T
Sbjct: 254 SKTPQRIQENIDILDFALSPQELEQMNQLDENLHT 288
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 115 bits (276), Expect = 1e-24
Identities = 59/153 (38%), Positives = 89/153 (58%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W MEE + G K+IG+SNF ++ + I P V Q+E+N Q K I+
Sbjct: 112 DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNIE 171
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
++ G+ V A++PF +D + P L IAEK+GKSV Q++LR+LI++ ++ +
Sbjct: 172 ALRKEGVAVEAWAPFAEGKNDIFTN-----PILTKIAEKYGKSVAQVILRWLIEQDIIVL 226
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
KSVK R+ +N+ VFDF LS ED + I T N+
Sbjct: 227 AKSVKPERMAQNLAVFDFELSEEDKSAIATLNQ 259
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 115 bits (276), Expect = 1e-24
Identities = 64/158 (40%), Positives = 97/158 (61%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D + WK ME +LGLAKSIGISNF ++IL +I P+ +Q+E++ +L Q +L++
Sbjct: 137 DAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVE 196
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ K GI V+++S G S +R DD T+ AIA+K+G + +QI+L Y+ +G+ I
Sbjct: 197 FMKSKGIQVISYSSLGSA-PGSSAKVR-DDKTIKAIAKKYGCAPSQIILSYITAQGICVI 254
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV 484
PKS K + ENID+ + LS ED++ I N R V
Sbjct: 255 PKSRSKEHLRENIDLKE--LSREDISAIDALNTGHRYV 290
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 114 bits (275), Expect = 2e-24
Identities = 59/153 (38%), Positives = 90/153 (58%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+ +EE + G +SIG+SNFN +D +LE +I+P V Q+E+ ++ Q ++ Y
Sbjct: 142 ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTF 201
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
R GI V A+ P G L DDP + IA +HGKS Q++LR+ +Q+G+V IP+
Sbjct: 202 RKGIQVEAWGPLGQGVTGVL-----DDPAIGEIAARHGKSAAQVILRWHMQRGLVTIPRC 256
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
+ENI +FDF LS +M I N+ +R
Sbjct: 257 DNDAYTDENIRIFDFELSPSEMEIITGLNRNQR 289
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 114 bits (275), Expect = 2e-24
Identities = 59/148 (39%), Positives = 90/148 (60%), Gaps = 2/148 (1%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL--ENGQIKPSVLQVEVNLHLGQDKLID 190
L TW+ +EEA G +SIG+SN+ + +L E +I+P V QVE+N L + +L+
Sbjct: 131 LGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQ 190
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
YC+ N I V AFSP + R DDP L +A ++ K V QI++R+ IQ G + +
Sbjct: 191 YCRENNIAVQAFSPL-------MRGKRLDDPILQKVAHQYDKGVAQILVRWSIQMGFIVL 243
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
PK+ KK R+ N D++DF LS+E M+++
Sbjct: 244 PKAAKKERLAPNFDIWDFELSAETMSEL 271
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 114 bits (274), Expect = 2e-24
Identities = 63/155 (40%), Positives = 94/155 (60%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+DT+K E+ G ++IG+SNF ++R+ + P+V Q+E++ HL Q +
Sbjct: 119 YVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREV 178
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
GI A+SP G S I D P +VAIA+KHG++ Q+VLR+ +Q G V IP
Sbjct: 179 HAEQGIATEAWSPLG-----SGKGIL-DIPAIVAIAQKHGRTPAQVVLRWHLQLGNVVIP 232
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KSV +RI+ENIDVF F+L +ED+ I N+++R
Sbjct: 233 KSVTPSRIKENIDVFGFSLDTEDLAAISALNEDRR 267
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 113 bits (272), Expect = 4e-24
Identities = 58/153 (37%), Positives = 94/153 (61%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+ +E+A+ G KSIG+SNF Q+ + +KP V Q+EVN ++ +
Sbjct: 115 DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNPWFQREPEVK 174
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ +++ + V A++PF D + + +P L I +K+GKS Q++LR+LIQ+G++ I
Sbjct: 175 WNQKDDVAVEAWAPFAEG-KDGIFT----NPVLTEIGKKYGKSNGQVILRWLIQRGIIVI 229
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
PKSV R +ENID+FDF L+++DM KI +K
Sbjct: 230 PKSVHDARQKENIDIFDFELNNDDMQKIAALDK 262
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 113 bits (272), Expect = 4e-24
Identities = 59/155 (38%), Positives = 91/155 (58%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
YL+TW MEE G K IG++NF ++ ++++ +I P + Q+E + Q++L Y
Sbjct: 117 YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQY 176
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
++ I+ A++P G L ++ L IA H K+V Q++LR+ IQ+G++ IP
Sbjct: 177 LTKHKILHEAWAPLGQGNKALL-----ENTVLKKIASNHEKTVAQVILRWHIQRGIIIIP 231
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS RI+ENI +FDF LSSE+M KI N KR
Sbjct: 232 KSSNPKRIKENIQLFDFELSSEEMEKINQLNTGKR 266
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 112 bits (270), Expect = 7e-24
Identities = 54/155 (34%), Positives = 98/155 (63%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY WK +E G+ K+IG+SNF ++ + +KP + Q+E++ + + +
Sbjct: 112 DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLRQRIEDLH 171
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ + G+ V +++ FG + + ++P LV++AEK+ K+V QI+LR+LIQ+ +V I
Sbjct: 172 WNNKYGVAVESWASFGRATSEIM-----ENPILVSLAEKYNKTVPQIILRWLIQQNIVVI 226
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
PK+V ++R++EN+D+FDF +S +DM+ I T N+ K
Sbjct: 227 PKTVTESRLKENMDIFDFEISDDDMDLIKTINQNK 261
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 112 bits (270), Expect = 7e-24
Identities = 63/180 (35%), Positives = 99/180 (55%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
VD TWK ME + G A++IG+SNF+T ++ +LE ++ P+V QVE + Q KL
Sbjct: 134 VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQ 193
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
++CK G+ + A+SP G L S +P L +AEK GKS Q+ LR+ +Q G
Sbjct: 194 EFCKSKGVHLSAYSPLGSPGTTWLKSDVLKNPILNMVAEKLGKSPAQVALRWGLQMGHSV 253
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSDQVHD 547
+PKS + RI+EN +VFD+++ K + + G SF P++ +++ D
Sbjct: 254 LPKSTNEGRIKENFNVFDWSIPDYMFAKFAEIEQARLVTG-SFLVHETLSPYKSIEELWD 312
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 112 bits (270), Expect = 7e-24
Identities = 59/143 (41%), Positives = 87/143 (60%), Gaps = 1/143 (0%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQI-KPSVLQVEVNLHLGQDKLIDYC 196
+ W+ +E+ G KSIG+SNF I+ + ++ P V Q+E++ Q + YC
Sbjct: 127 ELWQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYC 186
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
KRNGIVV A+SP + + + +DPTLV +A+K+GK+ Q+++RY +QK VP+PK
Sbjct: 187 KRNGIVVEAYSPL-------VRNYKANDPTLVDLAKKYGKTTAQVLIRYALQKHWVPLPK 239
Query: 377 SVKKNRIEENIDVFDFNLSSEDM 445
S RIE N VFDF +S EDM
Sbjct: 240 SDTPERIEANTKVFDFEISEEDM 262
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 112 bits (270), Expect = 7e-24
Identities = 60/181 (33%), Positives = 99/181 (54%), Gaps = 1/181 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D WK ME GL K IG+ N+ T+++R+L + +I P+V Q+E++ DK+ +
Sbjct: 143 DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFE 202
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
CK++GI V A+SP G S DP + +A K K+ Q+++++ +Q+G I
Sbjct: 203 ACKKHGIHVTAYSPLG-----SSEKNLAHDPVVEKVANKLNKTPGQVLIKWALQRGTSVI 257
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV-GMSFWQDHPYYPFEKSDQVHD 547
PKS K RI+ENI VF + + ED + + EKR + G + + + P+ + V D
Sbjct: 258 PKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLTGEELFVNKTHGPYRSAADVWD 317
Query: 548 N 550
+
Sbjct: 318 H 318
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 112 bits (269), Expect = 9e-24
Identities = 57/149 (38%), Positives = 88/149 (59%), Gaps = 1/149 (0%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENG-QIKPSVLQVEVNLHLGQDKLIDYCKR 202
W+ ME AK A++IG+SNF +D + E + PSV Q+E++ Q +++ YC+
Sbjct: 131 WEAMERAKREARARNIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQD 190
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
N I++ A+SP R +DP + I+ KH KS Q+++RY +QKG VP+PKS
Sbjct: 191 NEIIIEAYSPLAT-------GARLEDPLVEGISTKHDKSHAQVLIRYSLQKGWVPLPKSS 243
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
+ +RI EN +VFDF L +DM + +K
Sbjct: 244 RPDRISENFNVFDFVLDEDDMETLDDLDK 272
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 112 bits (269), Expect = 9e-24
Identities = 57/148 (38%), Positives = 95/148 (64%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
WK MEE GL ++IG+SNF ++ ++ + +I P+V Q+E++ + + I++ +
Sbjct: 122 WKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNY 181
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
I A+ PF + +I + L +IAEK+GK+V Q++LR+L QKG+V IPK+V+
Sbjct: 182 NIQPEAWGPFA----EGRKNIFQNG-VLRSIAEKYGKTVAQVILRWLTQKGIVAIPKTVR 236
Query: 386 KNRIEENIDVFDFNLSSEDMNKIGTFNK 469
+ R++ENI +FDF L+ EDM KI T ++
Sbjct: 237 RERMKENISIFDFELTQEDMEKIATLDE 264
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 112 bits (269), Expect = 9e-24
Identities = 59/156 (37%), Positives = 97/156 (62%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++ W+ + E K G AKS+G+SNF + ID+I E G PSV Q+E++ L Q +L+
Sbjct: 121 YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLS 180
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C+ +GI + ++ PF F L + P L A+++GK+ Q++LR+ IQKG V P
Sbjct: 181 CRNDGIQIESWGPFA-RFSKDLDAF----PELTRPAKQYGKTPAQVILRWHIQKGYVVFP 235
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
K+V R+ +NID+FDF+L+ ++++ I + + RT
Sbjct: 236 KTVHAERLRQNIDIFDFDLTPDEISGIDSLDAGFRT 271
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 112 bits (269), Expect = 9e-24
Identities = 57/151 (37%), Positives = 92/151 (60%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
L+ WK +EEA + G K+IG+SNF+ ++D +L N +IKP+V Q+E + ++L + C
Sbjct: 135 LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREAC 194
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
GI + A+SP +L D P + IA KHGK+ QI+L++ + G + +PK
Sbjct: 195 ISRGIHIQAYSPMAQ--GQAL-----DRPEIKTIASKHGKTPAQILLKWGLTHGNIILPK 247
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
S+ K+RIE N +FDF L S+DM+ + ++
Sbjct: 248 SLTKHRIESNAQLFDFELDSDDMDVLDNLDE 278
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 111 bits (268), Expect = 1e-23
Identities = 54/151 (35%), Positives = 92/151 (60%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++TW+ E + GL +SIG+SNF I+R++E+ + P+V Q+E++ H Q + DY
Sbjct: 117 YVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDY 176
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
GI + ++SPFG + +R + ++ +A +H S QIVLR+ +Q+G+ P+P
Sbjct: 177 HHEAGIAIQSYSPFG---SNGAAVLR--NAVVMVLARRHDHSPAQIVLRWHLQQGLTPLP 231
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
++ R EN+DV+DF LS E+M + + N
Sbjct: 232 RTTNGARFSENVDVWDFELSEEEMKLLASLN 262
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 111 bits (268), Expect = 1e-23
Identities = 58/152 (38%), Positives = 89/152 (58%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+ ME A G K+IG+SNF+ Q+ + E IKP + Q+EVN K I
Sbjct: 116 DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDIT 175
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
Y + G+ V A++PF +D +I L IA+KH KS+ QIVLR+L Q+ ++ +
Sbjct: 176 YFSQYGVQVEAWAPFAEGKNDLFSNI-----LLRKIADKHHKSIAQIVLRWLTQRNIIVV 230
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
KSVK R+ +N+D+FDF L+ +++ +I T +
Sbjct: 231 AKSVKPERMAQNLDIFDFKLTHQELAEIETLD 262
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 111 bits (268), Expect = 1e-23
Identities = 53/157 (33%), Positives = 99/157 (63%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y ++W+ +E+ G AK+IG+ NFN ++ +L++ +IKP++ Q+E N + Q K++ +
Sbjct: 127 YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKF 186
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C+ N I + A+SP G + L S + + IA++H KS Q++LR+ IQ+G + +
Sbjct: 187 CRENDIQLEAWSPLG---NGRLLS----NDVIKQIADEHQKSPAQVILRWEIQQGFIVLT 239
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV 484
K+ R++EN ++FDF LS ++M +I ++EK ++
Sbjct: 240 KTTHPQRMKENAEIFDFTLSPDEMKQIDKLDQEKHSI 276
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 111 bits (268), Expect = 1e-23
Identities = 57/155 (36%), Positives = 95/155 (61%), Gaps = 1/155 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG-QIKPSVLQVEVNLHLGQDKLI 187
D +++WK +E+ G ++IG+SNF I +L++ +I P V Q+E++ Q K++
Sbjct: 116 DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVV 175
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
DYC+ GI + A++P + H + + L+AIA K+ KS QI++RY +Q+G +
Sbjct: 176 DYCESKGIQLAAYAP---LVHGE----KFGNKQLLAIASKYNKSEAQIMIRYCLQRGFIV 228
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
+PKS RI+EN DVFDF +S EDM K+ +++
Sbjct: 229 LPKSSTPRRIKENGDVFDFEISKEDMEKLYNLDED 263
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 111 bits (268), Expect = 1e-23
Identities = 63/183 (34%), Positives = 103/183 (56%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY TW ME + G K IG+SNFN +++R+L + +I P+V Q+E++ +L Q +L+
Sbjct: 178 DYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVR 237
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+CK NGI ++A P G + +P A KH +S QI+L +++Q+G+ I
Sbjct: 238 FCKANGIHLVAHQPLGG------KPVAAVNPNADRPASKHERSPAQIILSWIVQQGISVI 291
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSDQVHDN 550
PK+V+++R+ EN+D+ L +DM I +K+K V + + F D+ HD
Sbjct: 292 PKTVRQSRMVENLDL--KQLPDKDMETIYDLSKKKGEV--RYLDPKNHIGFNIFDERHDQ 347
Query: 551 PFQ 559
P Q
Sbjct: 348 PVQ 350
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 111 bits (266), Expect = 2e-23
Identities = 58/169 (34%), Positives = 94/169 (55%), Gaps = 1/169 (0%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+GMEE LGLA+SIG+SNF+ ++ R+L + P+V QVE+N+ Q+K+ +
Sbjct: 158 DMEGVWRGMEECHRLGLARSIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVRE 217
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
C G+VV A+SP G + L +A K++ Q+ LR+L ++GV +
Sbjct: 218 VCGEGGVVVAAYSPLGAHGAHWGSDAVMNSGVLHDVAAARCKTIAQVALRWLYEQGVCMV 277
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQ-DHPY 514
+S + R+++N+D+FD+ LS +D I + + G F D PY
Sbjct: 278 ARSFNEGRMKQNMDIFDWELSDQDKAMIAGVPQRRACHGNYFVSPDGPY 326
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 111 bits (266), Expect = 2e-23
Identities = 62/186 (33%), Positives = 106/186 (56%), Gaps = 18/186 (9%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
D W+G E+ LGL K+IG+SNFN +QI RI+ ++ Q+E++L+L Q + CK
Sbjct: 133 DIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCK 192
Query: 200 RNGIVVMAFSPFG-------------PMFHDSLPSIRP-DDPTLVAIAEKHGKSVTQIVL 337
++ I++ A++ G P+F + S +D + A+A+K+ K+ QI+L
Sbjct: 193 KHNILITAYATLGSPGRMSVVGSNGRPLFESTQNSENEMNDKHVKALAQKYSKTPAQILL 252
Query: 338 RYLIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW----QD 505
R ++ G++ IPK+ R++ENI++FDFN+S+ ++N + + K+ FW D
Sbjct: 253 RATVEMGIIVIPKTTNPERMKENINIFDFNISNAEVNLLEAHERTKQE--RLFWWPNVAD 310
Query: 506 HPYYPF 523
HP PF
Sbjct: 311 HPEDPF 316
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 110 bits (265), Expect = 3e-23
Identities = 58/148 (39%), Positives = 86/148 (58%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D TW ME+ G AK+IG+SN I+ I++ G++ P+V QVE++ + Q L+
Sbjct: 168 DQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLK 227
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
YCK GI++ A+SP G S S +DP L+A+A+KH +++ Y + +GVV +
Sbjct: 228 YCKEKGILLEAYSPLG-----STSSPLHEDPDLLAVAKKHNVPTATVLISYQVNRGVVVL 282
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
PKSV RIE N+ L EDMNK+
Sbjct: 283 PKSVTPARIESNLKT--IKLDEEDMNKL 308
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 110 bits (264), Expect = 4e-23
Identities = 58/155 (37%), Positives = 91/155 (58%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
YLD+W+ ME+ G K+IG+SNFN TQ+ IL +G +KP V Q+E + + Q+ + Y
Sbjct: 123 YLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAY 182
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ GI+ A+SP G +++L D + +A H S QI+LR+ +Q+ V IP
Sbjct: 183 LESQGILHEAWSPLGGGNNNAL-----TDSVINELAAAHDVSAAQIILRWHVQREEVVIP 237
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS+ + RI++N D+F F L ++M I + KR
Sbjct: 238 KSIHEARIQQNRDIFAFGLDEDEMKAISDLDTGKR 272
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 109 bits (263), Expect = 5e-23
Identities = 52/145 (35%), Positives = 92/145 (63%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+ ME+ N G ++IG+SNF I +++ ++ P+V Q+EV+ +++ Y +
Sbjct: 131 ETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQ 190
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+ I+V A++P G L + PT++ IA+K+ K+ Q+ LR+++Q+G++P+PKS
Sbjct: 191 AHNILVEAWAPLGGQGAKVLTN-----PTMIQIADKYQKTPAQVCLRWVLQQGILPLPKS 245
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKI 454
V K R+ N ++FDF L+ EDM KI
Sbjct: 246 VHKERMISNQNIFDFELTDEDMRKI 270
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 109 bits (262), Expect = 6e-23
Identities = 58/159 (36%), Positives = 100/159 (62%), Gaps = 4/159 (2%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE-NGQIKPSVLQVEVNLHLGQDK-- 181
D ++ W+ +E AKN GLA++IG+SNF + IL+ N P V Q+E + +L QD+
Sbjct: 137 DLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYL-QDQTP 195
Query: 182 -LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
+++Y ++ GI++ A+ P GP+ P P D L ++EK+ ++ QI+LR+++Q+G
Sbjct: 196 GIVEYSQQQGILIEAYGPLGPITQGR-PG--PLDKVLSKLSEKYKRNEGQILLRWVLQRG 252
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
++PI + K+ RI + +++FDF L ED ++I KEK
Sbjct: 253 ILPITTTSKEERINDVLEIFDFELDKEDEDQITKVGKEK 291
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 108 bits (260), Expect = 1e-22
Identities = 57/148 (38%), Positives = 89/148 (60%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TWK MEE G K+IG+SNF I+ + ++ +I P V Q+E + Q ++++YC++
Sbjct: 135 TWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQK 194
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
N IVV A+SPF S ++ TLV +A+K+ +V Q++L ++IQK +VP+PKS
Sbjct: 195 NNIVVQAWSPFS-------QSKVLENKTLVQLAKKYEVTVAQLILNWIIQKDIVPLPKSK 247
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFN 466
RI N DVF+F ++ D+ I N
Sbjct: 248 TPERIRSNFDVFNFGINQADLKVIDQLN 275
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 107 bits (257), Expect = 3e-22
Identities = 55/153 (35%), Positives = 88/153 (57%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY TW+ +E G ++IG+S+F ++ ++ +KP+V Q+E N+ + K
Sbjct: 113 DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQ 172
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
Y ++ G+ A++PF + + P L IAEKH K+ Q++LR+ +Q+ V I
Sbjct: 173 YMEKEGVQPEAWAPFAEGANHIFTN-----PLLEEIAEKHHKTTAQVMLRWFLQRNYVVI 227
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
PKSV K R+ EN DVFDF L ++DM KI T ++
Sbjct: 228 PKSVHKKRLAENYDVFDFELDADDMKKIKTLDQ 260
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 107 bits (256), Expect = 3e-22
Identities = 55/161 (34%), Positives = 94/161 (58%), Gaps = 8/161 (4%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW ME + LA+SIG+SNF+ + +L +I+P+ LQ+E + +L Q++L+ Y +
Sbjct: 146 ETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQ 205
Query: 200 RNGIVVMAFSPFGPMFHDSL--------PSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
+ GI V A+S FGP+ L P + D + IA+KHGK+ Q++LR+ Q+
Sbjct: 206 KEGIAVTAYSSFGPLSFVELDLKDAHETPKLF-DHDVIKGIAQKHGKTPAQVLLRWATQR 264
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
+ IPKS R+ +N+DV ++L + ++ I + N+ R
Sbjct: 265 NIAVIPKSNDPTRLAQNLDVTGWDLETSEIEVISSLNRNLR 305
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 106 bits (255), Expect = 5e-22
Identities = 57/180 (31%), Positives = 104/180 (57%), Gaps = 9/180 (5%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
+ V +TW ME K GL + IG+SNF+ + IL+ G+++P + QVE++ +L Q +
Sbjct: 132 EAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVEMHPYLPQPE 191
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDD-PTLVA------IAEKHGKSVTQIVLR 340
L+ + + + I + A+SP G D +++ DD PTL+A IA++HG S Q++L+
Sbjct: 192 LVSFAEAHNIPITAYSPLGS--GDRPDAMKADDEPTLMANPTINDIADRHGVSPAQVLLQ 249
Query: 341 YLIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW--QDHPY 514
+ + +G IPKS I++N+ D +LS++++ I + + + R + + W + PY
Sbjct: 250 WGVARGTAVIPKSTTPAHIKDNLAAADLDLSADELETIDSLDSKYRYLAGAAWTMEGSPY 309
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 106 bits (254), Expect = 6e-22
Identities = 59/156 (37%), Positives = 93/156 (59%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
YL+TWK ++ ++ GL +SIG SNFN ++RI+ P + Q+E+N L Q ++
Sbjct: 118 YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAV 177
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
K +G+V A++P G + S +P A+A + GKS Q++LR+ +Q G IP
Sbjct: 178 HKAHGVVTQAWTPLG-----NARSFEA-EPITKAVA-RTGKSPVQVILRWHVQLGNAVIP 230
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
+SVK +R EN+DVFDF L+ +M++I T + RT
Sbjct: 231 RSVKAHRQAENLDVFDFTLTEAEMSEIATLDMGLRT 266
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 106 bits (254), Expect = 6e-22
Identities = 55/152 (36%), Positives = 93/152 (61%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+++ TWK E + G +SIG+SNF ++R++ + P+V Q++V+ + + I
Sbjct: 117 EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIA 176
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
Y +R+GIV ++SP G D L + P L IA+KHGK+ QIVLR+ +++G+V I
Sbjct: 177 YNRRHGIVTESYSPLGAG-SDLLNA-----PVLGRIAQKHGKTPGQIVLRWHVEQGLVAI 230
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
PK+ R++EN+D+F F L ++D + I T +
Sbjct: 231 PKTANPQRMKENLDIFGFTLDADDTSAIATLD 262
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 105 bits (253), Expect = 8e-22
Identities = 63/163 (38%), Positives = 89/163 (54%), Gaps = 4/163 (2%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
DTW ME+ G K++G+SNF + +L++ IKP+V Q+E + Q + +C
Sbjct: 125 DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCN 184
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
N I V +SP G D D+ L +A K+ K+V Q+ +R+ IQ V+P+PKS
Sbjct: 185 DNNIQVEGWSPLGR--GDVF-----DNEVLKQLAHKYNKTVAQLSIRWAIQNNVIPLPKS 237
Query: 380 VKKNRIEENIDVFDFNLSSEDM---NKIGTF-NKEKRTVGMSF 496
V NRI EN +V DFN+S DM NKI T N R +SF
Sbjct: 238 VTPNRIIENFEVSDFNISESDMALINKIDTIANSGLRPDSVSF 280
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 105 bits (253), Expect = 8e-22
Identities = 55/143 (38%), Positives = 85/143 (59%), Gaps = 1/143 (0%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQI-KPSVLQVEVNLHLGQDKLIDYC 196
+ W+ +E G +SIG+SNF I+ + ++ P V Q+E++ Q + YC
Sbjct: 127 ELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYC 186
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
KRNGIVV A+SP + + + +DPTLV +A+K+ ++ QI++RY +QKG VP+PK
Sbjct: 187 KRNGIVVEAYSPL-------VRNYKANDPTLVDVAKKYERTTAQILIRYALQKGWVPLPK 239
Query: 377 SVKKNRIEENIDVFDFNLSSEDM 445
S RI N +VFDF + ED+
Sbjct: 240 SDTPERIVANANVFDFEIGEEDL 262
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 105 bits (252), Expect = 1e-21
Identities = 51/148 (34%), Positives = 90/148 (60%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D++ T++ MEE G ++IG+SNFN + +++ IKP V QVEVNL + ++L +
Sbjct: 146 DFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRN 205
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
Y +G+ + A+SPFG + S+ +DP +V +A+++ + Q++L + + + ++PI
Sbjct: 206 YAHAHGVTLQAYSPFGSN-QNVAKSL--EDPVVVDVAQRNNITPAQVLLAWTLGRDIIPI 262
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
KSV RIEEN V D L+ E++ +
Sbjct: 263 SKSVTPERIEENFRVLDIQLAEEEIKHL 290
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 105 bits (252), Expect = 1e-21
Identities = 59/155 (38%), Positives = 86/155 (55%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
YLD+W+ E+ ++IG+SNF+ ++ +L + P V QVE++ Q L +
Sbjct: 127 YLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAF 186
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C I V A+SP G L S +P L AI K+ K+ Q++LR+ IQK ++ IP
Sbjct: 187 CDAKQIKVEAWSPLG---QGKLLS----NPILSAIGAKYNKTAAQVILRWNIQKNLITIP 239
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KSV + RIEEN D+FDF L +ED+ I N R
Sbjct: 240 KSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 274
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 105 bits (252), Expect = 1e-21
Identities = 61/181 (33%), Positives = 101/181 (55%), Gaps = 9/181 (4%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V +DT++ +EE + GL KSIG+SNF + I +L +IKP LQ+E + +L Q+ L+
Sbjct: 146 VPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLV 205
Query: 188 DYCKRNGIVVMAFSPFGPM-FHDSLPSIRPDDPTLV------AIAEKH-GKSVTQIVLRY 343
++CK + I V+A+S FGP F + + PTL +++ H G + +Q++LR+
Sbjct: 206 EFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRW 265
Query: 344 LIQKGVVPIPKSVKKNRIEENIDV-FDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYP 520
Q+G+ IPKS KK R+ N+++ F L+ +++ I N R W D +
Sbjct: 266 ATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDPWTWLDGKFPT 325
Query: 521 F 523
F
Sbjct: 326 F 326
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 104 bits (250), Expect = 2e-21
Identities = 54/154 (35%), Positives = 93/154 (60%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
++ WK MEE G ++IG+SNF+ + + ++EN +IKP V Q+ + Q+ + +C
Sbjct: 128 IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFC 187
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
+ NGI+V A+SP + I ++ + IA+K+GK++ Q+ + Y +QKGV+P+PK
Sbjct: 188 QDNGILVEAYSPL------ATGKIL-ENAEIQKIADKYGKTLPQVCICYCLQKGVLPLPK 240
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
S + I +N DV DF +SSEDM + + ++
Sbjct: 241 STHEAFILQNADV-DFEISSEDMQYLDQLKETEK 273
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 104 bits (250), Expect = 2e-21
Identities = 57/167 (34%), Positives = 92/167 (55%), Gaps = 1/167 (0%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
+ V +TW+ ME+ + GL KSIG+SNFN + +L +IKP+ QVE++ L Q +
Sbjct: 132 EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPE 191
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
L +C ++ I + A+SP G D+ + AIA+K+ K++ ++ ++ IQK
Sbjct: 192 LKKFCDKHNIHLTAYSPLG-------NGAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNF 244
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG-MSFW 499
IPKS +R+ EN D+F+F + DM + +K RT FW
Sbjct: 245 SVIPKSSTPSRVAENFDLFNFEIEEADMLFLDKMDKNLRTCDPAKFW 291
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 104 bits (250), Expect = 2e-21
Identities = 56/154 (36%), Positives = 93/154 (60%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+++DTWK ME+ G K++G+SN++ ++++L + P+V QVE + L Q +L+D
Sbjct: 139 NHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVD 198
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+CK GI +MA+SP G L + +P +V IAEKH S ++L Y I +G+ I
Sbjct: 199 FCKEKGIHIMAYSPLGSTGGPLLTA----EP-VVKIAEKHSISPAAVLLGYQIARGITVI 253
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
PKSV +RI+ N + D L +EDM + ++++
Sbjct: 254 PKSVNPDRIKANAQLKD--LDAEDMKLLNDYSEQ 285
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 104 bits (250), Expect = 2e-21
Identities = 54/145 (37%), Positives = 88/145 (60%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+ WK + +A++ GL KSIG+SNF I ++ P+V QV+++ + ++++ C+
Sbjct: 149 NVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICE 208
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+N I++ A+ P ++R D P +V IA++ GK QI+LR+ IQ G V IPKS
Sbjct: 209 QNEILLEAWGPLAR-------AMRFDHPVVVKIAKEKGKDAAQIMLRWGIQHGFVVIPKS 261
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKI 454
V + RI N +FDF LSSE+M ++
Sbjct: 262 VSQKRIVSNSKIFDFELSSEEMKEL 286
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 104 bits (250), Expect = 2e-21
Identities = 56/152 (36%), Positives = 84/152 (55%), Gaps = 6/152 (3%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
+ +WK E+ G A++IG+ NF Q+D ++ + P+V Q+E++ + Q L+
Sbjct: 120 IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKN 179
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPD------DPTLVAIAEKHGKSVTQIVLRYLIQKG 358
+ GIV A+SP G +D DP + IAE HG+S Q++LR+ Q
Sbjct: 180 RALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQVILRWHFQND 239
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
VV IPKSV RI +NIDVFDF LS +M ++
Sbjct: 240 VVAIPKSVNPERIAKNIDVFDFALSDAEMAQL 271
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 104 bits (249), Expect = 2e-21
Identities = 59/143 (41%), Positives = 86/143 (60%), Gaps = 8/143 (5%)
Frame = +2
Query: 5 IVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQD 178
++ + +K MEE + GL K++GISNFN QI+++L +K P QVE + +L Q+
Sbjct: 135 LIHWPQGFKAMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 179 KLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVA------IAEKHGKSVTQIVLR 340
KLI YC GI + A+SP G P +P+DP+L+ IA KH K+ Q+++R
Sbjct: 195 KLIQYCHSKGITITAYSPLGS---PDRPWAKPEDPSLLEEPKIKEIAAKHKKTTAQVLIR 251
Query: 341 YLIQKGVVPIPKSVKKNRIEENI 409
+ IQ+ V+ IPKSV RI ENI
Sbjct: 252 FHIQRNVIVIPKSVTPARIVENI 274
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 104 bits (249), Expect = 2e-21
Identities = 58/154 (37%), Positives = 85/154 (55%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TW+ ME +SIG+SN++ +D +LE I P QVE++ Q L +YC
Sbjct: 124 TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCDE 183
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
GI+ M + P + +D TL IA K+ KS QI LR+ IQ+ V +PKS
Sbjct: 184 LGILTMGYCPLAKGKY-------LEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKST 236
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV 484
R++EN +VFDF LS+EDMN + +F+ + R +
Sbjct: 237 DCRRLKENTNVFDFELSAEDMNTLNSFSSQNRKI 270
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 103 bits (248), Expect = 3e-21
Identities = 56/155 (36%), Positives = 92/155 (59%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y ++W+ +E G K+IG+SNF ++ +L ++ P + QVE++ L Q ++ D+
Sbjct: 122 YKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDF 181
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C+++ I V A+SP + L S + T++AIAE H KS Q++LR+ IQ+ ++
Sbjct: 182 CEKHDIKVQAWSP---LMQGQLLS----NETILAIAENHNKSAAQVILRWDIQQDILLAV 234
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KSV K R+ N VFDF LS+E+M +I N+ R
Sbjct: 235 KSVHKERMISNAAVFDFELSAEEMAQINQLNESLR 269
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 103 bits (248), Expect = 3e-21
Identities = 58/156 (37%), Positives = 88/156 (56%), Gaps = 1/156 (0%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
L ++ +E+ G ++IG+SNF + R+L I P+V Q+EV+ + Q L
Sbjct: 134 LGAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLH 193
Query: 197 KRNGIVVMAFSPFGPM-FHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+GI+ A+SP G + F+ +DP L+ IA++HGKS Q++LR+ +Q+G IP
Sbjct: 194 AEHGILTQAWSPIGGITFYRGGEKSTLEDPVLLEIAQQHGKSAAQVMLRWHLQEGRSVIP 253
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
KS K RI EN DVFDF LS E + I + R+
Sbjct: 254 KSTKPARIAENFDVFDFELSGEQIAAIDALDTGVRS 289
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 103 bits (247), Expect = 4e-21
Identities = 56/155 (36%), Positives = 94/155 (60%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D + ++ +E+A G ++IG+SNF+ Q RIL+ ++ P++ QVE + + Q +L
Sbjct: 108 DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECHPYFPQTELKA 167
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
K + I + A+ P G +DS+ S +P + +AE+H KS Q++LR+ IQ+G + I
Sbjct: 168 LLKDHNITLQAWYPLGGRGNDSIMS----EPIVQGLAEEHSKSPAQVLLRWHIQQGHIVI 223
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
P S + I +NID+FDF L+ EDM +I + +K K
Sbjct: 224 PGSKTPSHIAQNIDLFDFALTDEDMAQIDSLDKGK 258
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 103 bits (247), Expect = 4e-21
Identities = 52/147 (35%), Positives = 87/147 (59%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+ +E GL ++IG+SNF ++ IL + + P V Q+E + QD+ + +C+
Sbjct: 126 ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQ 185
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+ I+V A+SP G + L + L +A +HG S QI LR+ +Q+GV+P+PKS
Sbjct: 186 NHSILVEAWSPLG---RNRLTG----NGVLTRLAAEHGVSPAQICLRFALQRGVLPLPKS 238
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGT 460
R+ EN+D+F F+L+ E+M + T
Sbjct: 239 SSPERMAENLDLFSFSLTGEEMAALST 265
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 103 bits (247), Expect = 4e-21
Identities = 55/157 (35%), Positives = 94/157 (59%), Gaps = 2/157 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRIL--ENGQIKPSVLQVEVNLHLGQDKL 184
+++ TW+ M+E G K++G+SNF+ + +L + ++ P+ QVE++ L QD+L
Sbjct: 146 NFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDEL 205
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
I++CK GIVV A+SP G P ++ +P ++ IA+K+ +V+ + +Q+G V
Sbjct: 206 INFCKSKGIVVEAYSPLG---STDAPLLK--EPVILEIAKKNNVQPGHVVISWHVQRGYV 260
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
+PKSV +RI+ N + F LS+ED I +KEK
Sbjct: 261 VLPKSVNPDRIKTNRKI--FTLSTEDFEAINNISKEK 295
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 103 bits (246), Expect = 6e-21
Identities = 52/164 (31%), Positives = 93/164 (56%), Gaps = 5/164 (3%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D V +TW ME+ GL + IG+ N++ + ++ +IKP++LQ+E + +L Q+
Sbjct: 147 DQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMSYARIKPAMLQIESHPYLTQEA 206
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPD-----DPTLVAIAEKHGKSVTQIVLRYL 346
L+ + + V AFSP G + + L + DP+++A A+++G + Q+VLR+
Sbjct: 207 LLRTARSYNMAVTAFSPLGSLSYVELNMAGANDTVLTDPSVLAAAQRNGVTAAQVVLRWG 266
Query: 347 IQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
IQ+G IPK+ R+ EN+ + +F L+ E+M+ I N+ R
Sbjct: 267 IQRGTAVIPKTSNPQRLIENLTLTEFTLNDEEMDAISALNQNHR 310
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 102 bits (245), Expect = 7e-21
Identities = 53/152 (34%), Positives = 89/152 (58%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY W+ +E+A G K+IG+SNF + E ++KP V QVE++ + Q + +
Sbjct: 122 DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALA 181
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
K + A++P G H ++ L +IA+ H KS++Q++LR+ IQ+GVV I
Sbjct: 182 TMKYYNVQPEAWAPLGGGRHKPF-----ENNLLQSIADAHQKSISQVILRWNIQRGVVVI 236
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
PKS + RIEEN ++DF+L+ ++M +I + +
Sbjct: 237 PKSTHQQRIEENFAIWDFSLTEKEMAQISSLD 268
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 102 bits (245), Expect = 7e-21
Identities = 55/152 (36%), Positives = 90/152 (59%), Gaps = 4/152 (2%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE--NGQI--KPSVLQVEVNLHLGQDKL 184
L W+ + EA+ G +SIG+SN+ ++ + E N + + SV Q E++ ++ +
Sbjct: 135 LGAWRALVEAQKAGHVRSIGVSNYGIHHLEELEEYINSGVGGEISVGQYEIHPWCAREDI 194
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
+ + K+ +V+ A+SP + + R D+P L +A+KH K+ QI++R+ +QKG V
Sbjct: 195 VAWLKKRNVVIEAYSPL-------VQAQRLDEPVLQNLAKKHNKTGAQILIRWSLQKGYV 247
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGT 460
P+PKSV +RI EN VFDF LS EDM + T
Sbjct: 248 PLPKSVTDSRIVENTQVFDFELSGEDMESLNT 279
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 102 bits (244), Expect = 1e-20
Identities = 57/167 (34%), Positives = 91/167 (54%), Gaps = 3/167 (1%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W EE GL ++IGISNFN + + +IKP V Q+EVN++ Q +L+++CK+
Sbjct: 134 WAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKL 193
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
+ V A+ P + +D L ++ K+ KSV QI+L++L+ GV IPK+
Sbjct: 194 NLHVTAYCPLARCQNTD------NDALLTELSTKYKKSVCQIMLQFLLSLGVSVIPKTQN 247
Query: 386 KNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV---GMSFWQDHPYY 517
R+ ENI+ DF+L D+ K+ NK R + +W+ PY+
Sbjct: 248 LERLRENIESTDFSLDEADIAKLKGLNKNFRLIDPYDREWWKRVPYF 294
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 102 bits (244), Expect = 1e-20
Identities = 54/150 (36%), Positives = 87/150 (58%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
L+TW+ +EE + GL ++IG+SNF ++ + ++G I P V QVE + KL+++C
Sbjct: 134 LETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHC 193
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
++ IV + P +L P ++ +A+K+G+S +QI +R+ IQ GVV IPK
Sbjct: 194 RKENIVFEGYCPLAK--GQALTH-----PHILELAKKYGRSASQICIRWSIQNGVVTIPK 246
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFN 466
S K +RI EN VF F L +M + T +
Sbjct: 247 STKPDRIYENCQVFGFRLEDSEMAALSTLH 276
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 101 bits (243), Expect = 1e-20
Identities = 52/151 (34%), Positives = 93/151 (61%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
+K +E+ G KS+G+SN+ +I+ L IKPS++Q E++++ + +++ Y
Sbjct: 148 YKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSLIQNEIHIYYQEKEVVPYMHNL 207
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
I + A+ PFG H S+ ++PT+V+IA+ H K+ QI+ R+L+Q+G++ I S
Sbjct: 208 NIAMQAWYPFGGRGHTF--SVL-NNPTIVSIAKDHNKTSAQIISRWLLQRGIITIVGSSN 264
Query: 386 KNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
I+ENI VFDF LS+++M I + +K ++
Sbjct: 265 PIHIKENISVFDFELSNQEMELIASLDKNEK 295
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 101 bits (243), Expect = 1e-20
Identities = 54/158 (34%), Positives = 91/158 (57%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++TWK + E K G KSIG+SNF + ++RI++ + P V Q+E++ Q L ++
Sbjct: 121 YVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELHPDFQQRALREF 180
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+++ I ++ P G S D + IAEKH ++ Q+V+R+ +Q G++ IP
Sbjct: 181 HEKHNIRTESWRPLGKGRVLS-------DERIGKIAEKHSRTPAQVVIRWHLQNGLIVIP 233
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
KSV R+ EN+DVF F L ++DM I +++ +G
Sbjct: 234 KSVNPKRLAENLDVFGFVLDADDMQAIEQMDRKDGRMG 271
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 101 bits (243), Expect = 1e-20
Identities = 53/145 (36%), Positives = 89/145 (61%), Gaps = 1/145 (0%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TW+ MEE + G+ K+IG+SN+ + ++LE +IKP+V Q+E++ L +L+++C +
Sbjct: 158 TWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQ 217
Query: 203 NGIVVMAFSPFGPMFHDSLPSIR-PDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
N I+ A+SP G R D+PTL A+A++ G S+ Q++L + +++G V +PKS
Sbjct: 218 NDILPEAYSPLGSQNQVPTTGERVRDNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPKS 277
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKI 454
+RIE N + + LS ED I
Sbjct: 278 STPSRIESNFIIPE--LSEEDFAAI 300
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 101 bits (242), Expect = 2e-20
Identities = 54/146 (36%), Positives = 90/146 (61%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
L+ W+ MEEA G +SIG+SNF I+ I+ NG I P+V Q+EV++ +L+DYC
Sbjct: 129 LENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYC 188
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
K+ GI + A+S P+ H L +D ++A A+K+ + Q++L + +Q G + IPK
Sbjct: 189 KKLGIKIEAYS---PLSHGKL----LNDDQIIAYAKKYNVTPAQLMLAFDMQLGCIVIPK 241
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKI 454
S ++EN+++ +F +S ED+ K+
Sbjct: 242 SDNVTEMKENLNI-NFKISDEDIAKL 266
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 101 bits (242), Expect = 2e-20
Identities = 59/161 (36%), Positives = 92/161 (57%), Gaps = 4/161 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DY+DT+K ME+ G K+IGISNF+ +++R+LE+ I P+V+Q+E++ L Q+ +
Sbjct: 134 IDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFV 193
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIR----PDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
++ K GI V +S G R +DP L AI K+GK+ Q+ L + I K
Sbjct: 194 EWLKSKGIHVTQYSSLGNQNEVYSGRERYGRLIEDPALAAIGTKYGKTGAQVALAWGITK 253
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
G + KS +RI++N + DF L EDM I +K+ R
Sbjct: 254 GHSVLVKSKTPHRIQQNFE-SDFELKQEDMKAIENIDKKLR 293
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 101 bits (242), Expect = 2e-20
Identities = 56/153 (36%), Positives = 91/153 (59%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
D W +E + G K+IG+SN++ ++ +L+ ++ P+V QVE++ L Q KL+ YCK
Sbjct: 142 DVWADVETLLDTGKVKAIGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCK 201
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
GI V A++P G + L DPT+V +A K+G S QIVL + + +GV PKS
Sbjct: 202 EKGIAVTAYTPTG--YQTVL-----TDPTIVELAGKYGVSPAQIVLAWHLSRGVAAAPKS 254
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
++R +EN+++ F L ED+ KI ++ +R
Sbjct: 255 ANESRQKENLNL-PF-LQPEDVAKISALDRGQR 285
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 101 bits (241), Expect = 2e-20
Identities = 53/155 (34%), Positives = 88/155 (56%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++++K +E G K+IG+ NF ++++++ +I P V Q+E++ + Q + D+
Sbjct: 117 YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDF 176
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C + I V A+ P M + L DDP + IA ++ K+ QIVLR+ + + IP
Sbjct: 177 CDEHDIKVTAWMPL--MRNKGLL----DDPVITDIAHRYDKTPAQIVLRWHLAHNRIIIP 230
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS RI+EN D+FDFNL D+ +I + NK R
Sbjct: 231 KSQTPKRIKENFDIFDFNLELTDVAEIDSLNKNAR 265
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 101 bits (241), Expect = 2e-20
Identities = 56/186 (30%), Positives = 103/186 (55%), Gaps = 3/186 (1%)
Frame = +2
Query: 2 DIVDY--LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQ 175
D++D+ W+ ME L ++IG+ NF T+++++L ++ P+V Q+E++
Sbjct: 165 DVLDFDMEGVWREMENLSKDSLVRNIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRN 224
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
D+++++CK+N I V A+SP G I D T+ IA+K K+ QI++++ +Q+
Sbjct: 225 DRILEFCKKNEIHVTAYSPLGSQ-EGGRDLIH--DQTVDRIAKKLNKTPGQILVKWGLQR 281
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV-GMSFWQDHPYYPFEKS 532
G IPKS+ RI+ENI VFD+ + +D + + +KR + G + + PF
Sbjct: 282 GTSVIPKSLNPERIKENIKVFDWVIPEQDFQALNSITDQKRVIDGEDLFVNKTEGPFRSV 341
Query: 533 DQVHDN 550
+ D+
Sbjct: 342 ADLWDH 347
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 101 bits (241), Expect = 2e-20
Identities = 50/136 (36%), Positives = 83/136 (61%)
Frame = +2
Query: 47 KNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAF 226
K GL +S+G+SNF ++ + + G P++ Q+E+N Q+++I YC ++GI V +
Sbjct: 132 KEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGY 191
Query: 227 SPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVKKNRIEEN 406
+P +F + D P LV ++E++GK+V QI++R+ +QK + IPKS RI EN
Sbjct: 192 AP---VFR----GCKFDHPVLVEMSERYGKTVAQIMIRWSVQKQYITIPKSSNPERILEN 244
Query: 407 IDVFDFNLSSEDMNKI 454
VFDF +S +DM +
Sbjct: 245 AQVFDFVISEKDMKNL 260
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 101 bits (241), Expect = 2e-20
Identities = 53/150 (35%), Positives = 85/150 (56%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+ W+ + A+ G K IG+SNF + + P+V Q+E++ Q ++ YC+
Sbjct: 129 NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPPP---VPAVNQIELHPFCQQRDIVKYCE 185
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+GI + A+SP D+ LV +A+K+GK V Q++LR+ +QKG +P+PKS
Sbjct: 186 EHGIAIEAYSPLVRANKKHY-----DNEVLVKVAKKYGKEVAQVLLRWSLQKGYIPLPKS 240
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
V +RIE N D++DF L EDM +I +K
Sbjct: 241 VTPSRIESNADLYDFKLDQEDMAEIDGLDK 270
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 100 bits (240), Expect = 3e-20
Identities = 54/155 (34%), Positives = 85/155 (54%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
+ +TW+ +E+ + GL ++IG+SNF +DR+ + + P V Q+E + H L Y
Sbjct: 119 FFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRY 178
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ IV A+SP G + L+ +A+KHGKS QIVLR+ +Q + IP
Sbjct: 179 LEELHIVHQAWSPLGR-------GGVLQEQILIDLAKKHGKSPAQIVLRWHLQNNISIIP 231
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS +RI EN D++DF L+ DM ++ N +R
Sbjct: 232 KSETPSRIRENADIYDFELTEADMRQVERLNNGER 266
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 100 bits (240), Expect = 3e-20
Identities = 55/162 (33%), Positives = 92/162 (56%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+Y W +E A G KSIGISNF+ ++ + IKPS LQVE + + Q +L +
Sbjct: 111 NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQKELQE 170
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ K G + ++ P G H + D+ L IA+K+ K+V QI+LR+ IQ+G++
Sbjct: 171 FLKPYGTKIESWYPLG---HGDQRLL--DESRLKKIAQKYNKTVAQIILRWHIQEGIIVF 225
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSF 496
P+S + + ENI++FDF LS ++ +I +K++ M++
Sbjct: 226 PRSTRVEHLAENINIFDFELSCTEIKEIRKLDKKQPYFTMTY 267
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 100 bits (239), Expect = 4e-20
Identities = 52/152 (34%), Positives = 86/152 (56%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y +TW+ + + + +G A SIG+SNF +D I+ + + P+V Q+E++ + Q +L Y
Sbjct: 115 YEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYFQQKELRAY 174
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
GIV ++SP G +DP + IA KHGK+ Q+VL + + G+ IP
Sbjct: 175 HAERGIVTTSWSPLG-------RGAALNDPVIREIALKHGKTPAQVVLNWHLSLGLTVIP 227
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
K+ K R++EN++ F L EDM +I + +K
Sbjct: 228 KASSKARLQENLEADSFALDEEDMQRIESLDK 259
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 100 bits (239), Expect = 4e-20
Identities = 56/178 (31%), Positives = 99/178 (55%), Gaps = 9/178 (5%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+ ME GL K+IG+SNF+ +++++LE I P+ QVE++ +L Q+KL ++C
Sbjct: 143 NTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCD 202
Query: 200 RNGIVVMAFSPFG------PMFH-DSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
GI++ A+SP G P + P + ++P + IA KH SV +++LR+ IQ+G
Sbjct: 203 SKGILLTAYSPLGNPGRLVPKERLEREPKVM-EEPVIKEIAAKHNCSVARVLLRWGIQRG 261
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR--TVGMSFWQDHPYYPFE 526
+PKS ++ + +N L+ ++M I + +R T G + + PF+
Sbjct: 262 YPVLPKSTSRDHLHDNFSALGLVLTDDEMAAIKSITTRQRYLTQGWMYAEGEYVDPFD 319
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 100 bits (239), Expect = 4e-20
Identities = 52/159 (32%), Positives = 89/159 (55%), Gaps = 6/159 (3%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+ W ME+ L ++IG++NFN I +L +IKP+VLQ+E++ L Q++L+ + +
Sbjct: 148 ECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQ 207
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVA------IAEKHGKSVTQIVLRYLIQKGV 361
GI V A+S FGP + L +L+A IA KH + QI+LRY + + +
Sbjct: 208 EQGIQVTAYSSFGPTSYVDLCESGKTYSSLLANADVKSIANKHNANTGQILLRYALDRNI 267
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
IPKSV ++R++ N+D+ + L +D + + +R
Sbjct: 268 AVIPKSVHEDRMKSNLDILNIQLDQDDRKILNSLKTNQR 306
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 100 bits (239), Expect = 4e-20
Identities = 51/145 (35%), Positives = 89/145 (61%), Gaps = 2/145 (1%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKLID 190
L+TW+ M+EA + GL KSIG+SN+ ID +L ++K P V Q+E++ + + +L D
Sbjct: 125 LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELAD 184
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
YCK G+VV AF+P + H + +P L+ + ++ ++ Q+++R+ +Q G +P+
Sbjct: 185 YCKSKGLVVEAFAP---LCH----GYKMTNPDLLKVCKEVDRNPGQVLIRWSLQHGYLPL 237
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDM 445
PK+ R+E N+ ++F LS E M
Sbjct: 238 PKTKTVKRLEGNLAAYNFELSDEQM 262
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 100 bits (239), Expect = 4e-20
Identities = 53/163 (32%), Positives = 95/163 (58%), Gaps = 3/163 (1%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK--LIDY 193
+ WK ME+ G AK+IG+SNF + RIL+ ++KP V Q+E + L + +
Sbjct: 137 EAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKF 196
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPS-IRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
C+ + I+V A+SP GP+ + +P + ++EK+ KS QI+LR++ ++GV+P+
Sbjct: 197 CQEHDILVEAYSPLGPLQKKTAQDDSQPFFEYVKELSEKYIKSEAQIILRWVTKRGVLPV 256
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
S K RI + ++F F+L++E+++KI E + + +W
Sbjct: 257 TTSSKPQRISDAQNLFSFDLTAEEVDKITELGLEHEPLRL-YW 298
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 99 bits (238), Expect = 5e-20
Identities = 55/161 (34%), Positives = 92/161 (57%), Gaps = 3/161 (1%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK--LIDYCK 199
WK ME G AKSIG+SNF+ I+ IL+ IKP V Q+E N L +++YC+
Sbjct: 140 WKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQ 199
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIR-PDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
+N I + A+SP GP+ S P + +A K+GK+ +QI+L ++ +G++PI
Sbjct: 200 KNNIQLEAYSPLGPLQKRPENSNELPFYNYIDELASKYGKTDSQILLNWVYNRGILPITT 259
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
S K RI + ++F FNL+ ++++ + E+ + + +W
Sbjct: 260 SSKTQRIIDAQNIFSFNLTKDEVDTLTKLGLEQPALRI-YW 299
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 99.5 bits (237), Expect = 7e-20
Identities = 49/153 (32%), Positives = 90/153 (58%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW +E + G ++IG+S+ + ++ I E +IKP+V+QVE + +L + +L+++CK
Sbjct: 148 ETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCK 207
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
RNGIV++AF+P G H P + +DP + +++E+ GK+ Q++L + +Q+G +
Sbjct: 208 RNGIVLLAFAPLG---HGMRPGLL-EDPVITSVSERVGKTAAQVLLSWAVQRGTALLTTP 263
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
R +EN D+ L E N+I +R
Sbjct: 264 RSAARAKENFDISP--LPEEAFNEINRIQTRQR 294
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 99.5 bits (237), Expect = 7e-20
Identities = 54/152 (35%), Positives = 81/152 (53%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
+L+TWK ME+ G A SIG+SNF ++ + I P+V Q+E + +LI+Y
Sbjct: 103 FLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEY 162
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C+ N I V A++P D+ L + K+ + QI LR+ +QKG+ IP
Sbjct: 163 CQANDIQVQAYAPLA-------RGAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIP 215
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
KSV RI N +FDF + EDM+ + T N+
Sbjct: 216 KSVHPERIASNARIFDFTIDQEDMDLLDTLNQ 247
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 99.5 bits (237), Expect = 7e-20
Identities = 51/150 (34%), Positives = 90/150 (60%), Gaps = 1/150 (0%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRIL-ENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+WK MEE + G +S+G+SN+ + + N + P V Q+E++ L QD ++ YC+
Sbjct: 127 SWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQ 186
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+ I + A+SP + H IR +D LV IA+K SV Q+++R+ +QKG +PI KS
Sbjct: 187 SHDIAIEAYSP---LTH----GIRLNDEKLVPIAKKLNISVAQLLIRWSLQKGYIPIIKS 239
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
KK + ++DVF+F + + + ++ +F++
Sbjct: 240 TKKEHMLSDLDVFNFTIPDDVVQELSSFDE 269
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 99.5 bits (237), Expect = 7e-20
Identities = 56/178 (31%), Positives = 94/178 (52%), Gaps = 3/178 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK--L 184
D W +E+ GLAK+IG+SN + +++ I++ +IKP V Q+E + L + +
Sbjct: 125 DLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEFHPLLQEPTPGI 184
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
+D+CK++ IVV +SP + L +P D + +A+ H S ++LR+ QKG+V
Sbjct: 185 VDFCKQHDIVVEGYSPLAS---NELEGEKPLDAVVANVAKNHNVSPGSVLLRWATQKGIV 241
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK-RTVGMSFWQDHPYYPFEKSD 535
PI S R +E + +FDF LS ++ +I E R + YYP E+ +
Sbjct: 242 PITTSANAGRQKEALAIFDFKLSDGEVEEISKVGAESPRYQRLPIPSHKHYYPAEEGE 299
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 99.5 bits (237), Expect = 7e-20
Identities = 50/137 (36%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Frame = +2
Query: 2 DIVDY--LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQ 175
D+VD DTW ME+ G +SIG+SNF +I+ +L+ +I P+V Q+E + L Q
Sbjct: 132 DVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQ 191
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
L+++ + GIVV +SP G ++ ++ DDP ++ A+K K+ Q+++ + +Q+
Sbjct: 192 RDLLEWSTQKGIVVAGYSPLGNNIYNIPRAV--DDPLVIETAKKLNKTPAQVLISWAVQR 249
Query: 356 GVVPIPKSVKKNRIEEN 406
G V +PKSV RIE N
Sbjct: 250 GTVVLPKSVTPERIESN 266
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 99.1 bits (236), Expect = 9e-20
Identities = 57/149 (38%), Positives = 88/149 (59%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TWK ME G KSIG+SNF+ ++ +L+ ++ P+V QVE++ L Q +L+++CK+
Sbjct: 171 TWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKK 230
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
N IV+ AFSPFG + P ++ + +V++A+K+ S I+ Y I G V IPKSV
Sbjct: 231 NNIVMTAFSPFGSV---GGPLLK--NELVVSLADKYNTSPGGILTSYHIGNGTVVIPKSV 285
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
+RI EN LS ED+ + +K
Sbjct: 286 TNSRIVEN-GKSAVTLSQEDLKALNDLHK 313
>UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 182
Score = 99.1 bits (236), Expect = 9e-20
Identities = 49/147 (33%), Positives = 84/147 (57%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
D W ME K G AK+IG+ NF + ++ I+ P+V Q+E + +L Q +L YC+
Sbjct: 20 DVWAEMEAVKASGKAKAIGVCNFAISHLETIIAGASEIPAVNQIEYHAYLQQSELSAYCQ 79
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+NGI V AF+ P + P + +A+K+G T+I LR+ +QKGV + S
Sbjct: 80 KNGIKVEAFASLAPWITEG-----PAKGVVAELAQKYGVGETEICLRWCVQKGVPVVTTS 134
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGT 460
+K+ R++ + VFDF+L +++ ++ +
Sbjct: 135 LKEERVKGYLKVFDFSLEDKEIEQLSS 161
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 98.7 bits (235), Expect = 1e-19
Identities = 55/166 (33%), Positives = 90/166 (54%), Gaps = 6/166 (3%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+T M EAK GL K +G+SNF+ +++ + + P + QVE++ +L Q+ L YC
Sbjct: 139 ETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYCS 198
Query: 200 RNGIVVMAFSPFGP------MFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
+ GI++ +SP G M D PS+ DD T+ +AE++ S Q ++ + Q+G
Sbjct: 199 KEGILLTGYSPLGSGDRSEGMKADDEPSLFEDD-TIKKVAERNNISKGQTLIAWAKQRGT 257
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
IPKS + RI+EN++ + LS ED+ I K R + F+
Sbjct: 258 AVIPKSTNEGRIKENLESDNIELSKEDLEDIANIGKNYRFIDGEFF 303
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 98.7 bits (235), Expect = 1e-19
Identities = 57/154 (37%), Positives = 90/154 (58%), Gaps = 7/154 (4%)
Frame = +2
Query: 89 NTTQIDRILENGQI--KPSVLQV-EVNLHLGQDKLIDYCKRNGIVVMAFSPFG----PMF 247
+T +++ IL + KP+ QV E + +L Q KL+++CK IV++A+S G P +
Sbjct: 150 DTWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQW 209
Query: 248 HDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVKKNRIEENIDVFDFN 427
D ++P L +IA+KH +S Q+ LRY +Q+GVV + KS + RI+EN +FDF
Sbjct: 210 VDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFE 269
Query: 428 LSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEK 529
L+ EDM I N+ R + +HPY+PF +
Sbjct: 270 LTPEDMKAIDGLNRNLRYDNAA---NHPYFPFSE 300
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 97.9 bits (233), Expect = 2e-19
Identities = 52/147 (35%), Positives = 84/147 (57%), Gaps = 1/147 (0%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG-QIKPSVLQVEVNLHLGQDKLIDY 193
L +WK +E+A G K G+SN+ +D ++ +IKP V Q+E + Q ++
Sbjct: 133 LTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAA 192
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C++ GIV+ A++P +R P L A+A+K+G + Q+++R+ +Q G V +P
Sbjct: 193 CEKYGIVIEAYAPLAR-------GMRMKHPVLTAVAKKYGVTPAQVLVRWSVQHGFVTLP 245
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
KS KK R+ EN DV F L+ EDM K+
Sbjct: 246 KSTKKERLVENADVGRFELAEEDMEKL 272
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 97.9 bits (233), Expect = 2e-19
Identities = 53/157 (33%), Positives = 87/157 (55%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V DTW +E+ +SIGISNF +ID +L+ +I P+V Q+E + +L Q L
Sbjct: 136 VPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLH 195
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
Y K I+ +A+SP G +++ P + DDP + AIA+K GK +++ + +Q+G
Sbjct: 196 KYLKEKNILSVAYSPLGNNIYNA-PRV-VDDPDVKAIADKLGKDPAALLISWAVQRGTAV 253
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
+PKSV +RIE N DF + + + ++ +R
Sbjct: 254 LPKSVTPSRIESNFQ--DFIIPDAEFEALNKLDRNQR 288
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 97.9 bits (233), Expect = 2e-19
Identities = 51/148 (34%), Positives = 88/148 (59%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+Y+ W+ M E + GL +SIG+SN ++RI+ + P+V Q+E++ Q ++ D
Sbjct: 116 NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITD 175
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ + + + ++ P G +D + +P + A A HGK+ Q VLR+ +QKG V
Sbjct: 176 WAAAHDVKIESWGPLGQGKYDLFGA----EP-VTAAAAAHGKTPAQAVLRWHLQKGFVVF 230
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
PKSV++ R+EEN+DVFDF+L+ ++ I
Sbjct: 231 PKSVRRERLEENLDVFDFDLTDTEIAAI 258
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 97.5 bits (232), Expect = 3e-19
Identities = 54/154 (35%), Positives = 90/154 (58%), Gaps = 3/154 (1%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
WK ME+ G ++IG+SN++ +RI++ I P+V+Q EV+++ QDK RN
Sbjct: 156 WKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEVHIY-NQDKQTKAFLRN 214
Query: 206 -GIVVMAFSPFGPM--FHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
G + A+ P G + + + DPT+V++A+K+ KS Q++LR+ +Q G + IP
Sbjct: 215 YGTQMEAWYPLGGRNSYGNGGKDVLFADPTIVSLAKKYAKSPAQVLLRWQLQAGNIAIPG 274
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
S I ENID+FDF LS ++M + +K+ +
Sbjct: 275 SSNPAHIRENIDIFDFALSDDEMATLSRLDKKSK 308
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 97.1 bits (231), Expect = 4e-19
Identities = 51/152 (33%), Positives = 91/152 (59%), Gaps = 1/152 (0%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILEN-GQIKPSVLQVEVNLHLGQDKLIDYCK 199
TW + E + GL +SIG+SN+ ++ +LE+ +KP V QVE + H QD+LI++C
Sbjct: 155 TWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKPDVNQVECHPHFRQDELIEFCT 214
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+ GI V A+S G +L +DP + IA + S +++L++ +Q+G+ IPK+
Sbjct: 215 KQGIHVQAYSSLGTSDTTNL----LEDPVVKKIASELNVSPARVLLKWALQRGLGIIPKA 270
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
+K + I++NI + DF +S + M + + ++K
Sbjct: 271 IKSDHIKDNIKL-DFEISKDQMTLLLSLPQQK 301
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 97.1 bits (231), Expect = 4e-19
Identities = 51/145 (35%), Positives = 84/145 (57%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
++W+ MEEA G ++IG+SNF +D ++E +IKP V Q+ +N Q +++ K
Sbjct: 130 ESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENK 189
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+ ++ A+SP G L + + +A +GKS Q+++R+ +Q G +P+PKS
Sbjct: 190 KLDLLSEAYSPLGT---GGLLG----NEVVKEVAANYGKSTAQVLIRWSLQHGFLPLPKS 242
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKI 454
V I+ N DVFDF +S EDM K+
Sbjct: 243 VHPEYIKANADVFDFEISPEDMAKL 267
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 97.1 bits (231), Expect = 4e-19
Identities = 53/153 (34%), Positives = 88/153 (57%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
LDTW+ +E ++IG+SNF+ Q+ ++ E +KP + Q+E + + Q L +
Sbjct: 117 LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFD 176
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
N IV +SP G H L +DP + +AEK+GKS QIVLR+ I G V PK
Sbjct: 177 TDNDIVNEGYSPIG---HGHLIL---EDPVITKLAEKYGKSPAQIVLRWQIDTGFVVFPK 230
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
S K R++EN ++ F+L+++++ +I +++K
Sbjct: 231 SSKPARVKENFEISGFSLTADEIAEINGLDQDK 263
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 97.1 bits (231), Expect = 4e-19
Identities = 56/158 (35%), Positives = 91/158 (57%), Gaps = 5/158 (3%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TWK ME+ G + IG+SNFN T ++RIL+ ++KP+V Q+E++ L Q + ++ K
Sbjct: 147 ETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHK 206
Query: 200 RNGIVVMAFSPFG---PMFHDSLPSIRPDDPTLVAIAEKHGKSVT--QIVLRYLIQKGVV 364
+ GI V A+SPFG ++ +P + + T+ IA+ G+ VT I + + I +G
Sbjct: 207 KLGIHVTAYSPFGNQNTIYESKIPKL-IEHETIQKIAKSKGEGVTGATIAVSWAITRGTS 265
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
IPKSV + RI+ N L+ EDM++I + R
Sbjct: 266 VIPKSVNEQRIKSNFKYIP--LTKEDMDEINSIGIRAR 301
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 96.7 bits (230), Expect = 5e-19
Identities = 55/158 (34%), Positives = 92/158 (58%), Gaps = 2/158 (1%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE-NGQIKPSVLQVEVNLHLGQD-KLIDY 193
+ W+ + A+ GL + IG+SN++ I+ +++ G+I P V QVE + G D +L Y
Sbjct: 100 ELWRALIRAREDGLTRDIGVSNYSIELIEELVDATGEI-PVVNQVEWS-PFGHDLELKHY 157
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
NGIV+ A+SP + R DD L AEK+GK+ Q+++R+ +++G VPIP
Sbjct: 158 ADFNGIVIQAYSPL-------TRATRLDDAALCETAEKYGKTPAQVLIRWNLERGTVPIP 210
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
K+ + ++ENI VFDF L D+ + + N+ ++G
Sbjct: 211 KANLHSHMKENISVFDFTLEKSDLESLDSLNEHFSSLG 248
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 96.7 bits (230), Expect = 5e-19
Identities = 50/148 (33%), Positives = 92/148 (62%), Gaps = 5/148 (3%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILE---NGQIKPSVLQVEVNLHL-GQDK-LID 190
W+ + EAK G + IGISN ++++ + + P V Q+E + L Q K ++
Sbjct: 143 WEALVEAKKAGKVREIGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVR 202
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+C+ +GI+V AFSP P+ ++ TL +AEK+ K+ Q++LRY +Q+G++P+
Sbjct: 203 FCQEHGILVEAFSPLAPLARVETNALAE---TLKRLAEKYKKTEAQVLLRYTLQRGILPV 259
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
S K++R++E++++FDF L+ E++N+I
Sbjct: 260 TTSSKESRLKESLNLFDFELTDEEVNEI 287
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 96.7 bits (230), Expect = 5e-19
Identities = 60/171 (35%), Positives = 93/171 (54%), Gaps = 10/171 (5%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
++DTW+ +E+ G ++IG+SNF+ +I+ +L P+V Q+EV+ +L Q ++
Sbjct: 166 FVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEW 225
Query: 194 CKRNGIVVMAFSPFGPM--FHDSLPSIRP--------DDPTLVAIAEKHGKSVTQIVLRY 343
+ GI V+ FSP G M F+ + D P L I +K+GKS Q+VL +
Sbjct: 226 LREKGIHVVQFSPLGNMNDFYRQAGWSKEIAHMMRVIDQPILKEIGQKYGKSPVQVVLAW 285
Query: 344 LIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSF 496
I G IPK+V +IEEN+ DF L +EDM +I T + + R SF
Sbjct: 286 GINSGRSVIPKTVIDWQIEENL-AADFELDAEDMARIATLDAKARFNDPSF 335
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 96.3 bits (229), Expect = 6e-19
Identities = 51/155 (32%), Positives = 86/155 (55%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+D+W G+ +AK G+A+SIG+ NFN + I++ P++ Q+E++ L Q +L +
Sbjct: 125 YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREV 184
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
GIV A+ P G D + +A+ HGK+ Q++LR+ IQ G V I
Sbjct: 185 NAGYGIVTEAYGPLG-------VGRLLDHAAVTGVAQAHGKTPAQVLLRWSIQLGNVVIA 237
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
+S +RI N++VFDF L+ ++M + ++ R
Sbjct: 238 RSANPDRITSNLEVFDFELTDDEMATLNGLDEGTR 272
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 96.3 bits (229), Expect = 6e-19
Identities = 55/157 (35%), Positives = 90/157 (57%), Gaps = 2/157 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE--NGQIKPSVLQVEVNLHLGQDKL 184
+++ TW+ M++ G K+IG+SNF+ + +L ++ P+V QVE + L Q++L
Sbjct: 144 NFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEEL 203
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
I YC GIV+ A+SP G ++ P + DPT+ IA+ +G +V+ + +QKG+V
Sbjct: 204 IQYCSEKGIVIEAYSPLGG---ENAPIL--SDPTVQEIAKANGVEAGHVVISWAVQKGLV 258
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
+PKSV +RI N+ V LS D+ K+ K K
Sbjct: 259 TLPKSVTPSRIVGNLKV--LTLSDSDVAKVDGLLKAK 293
>UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus
tropicalis|Rep: LOC548351 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 248
Score = 95.9 bits (228), Expect = 8e-19
Identities = 50/131 (38%), Positives = 79/131 (60%)
Frame = +2
Query: 53 LGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAFSP 232
LG+ +SIG+SNF +D++ E+ + P + QVE + +L+DYC+RN IV + P
Sbjct: 105 LGICRSIGVSNFLIHHLDQLKEDCNMVPHLNQVEYHPFQRPQELVDYCRRNNIVFEGYCP 164
Query: 233 FGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVKKNRIEENID 412
+L + P + IA+ +GK+ Q+ +R+ IQ G+V IPKS K+ RI+EN +
Sbjct: 165 LAK--GQAL-----NHPVIQKIAKNYGKTPAQVCIRWSIQNGIVTIPKSTKEERIQENCE 217
Query: 413 VFDFNLSSEDM 445
VF F L+ ED+
Sbjct: 218 VFGFVLADEDV 228
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 95.9 bits (228), Expect = 8e-19
Identities = 52/158 (32%), Positives = 85/158 (53%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
++DTWK + E ++ G AKSIG+SNF + RI++ + P++ Q+E++ Q +
Sbjct: 114 FVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKV 173
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ GIV ++SP G + + AIAE+ G+ T ++LR+ IQ G+ PIP
Sbjct: 174 HEDLGIVTQSWSPLG-------QGKGMSNEVIEAIAEETGQPETAVILRWHIQHGLCPIP 226
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
K+ ++ IE N F LS E M +I + K +G
Sbjct: 227 KASSRDHIEANFKALSFELSDEQMGRIDALDDPKGRMG 264
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 95.9 bits (228), Expect = 8e-19
Identities = 61/181 (33%), Positives = 92/181 (50%), Gaps = 4/181 (2%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TWK ME + G AK IG+SNF+T ++ R+L +I P V QVE+N + Q +L+ +C
Sbjct: 145 TWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHE 204
Query: 203 NGIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ I V A+ P G P +D T+ A+AE++ ++ QI+L +LI GV I
Sbjct: 205 HEIHVTAYGPLGCTPVPYLIGRKTPGPLEDCTVKAMAERYSRTPAQIILAHLIMLGVSVI 264
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSDQVHDN 550
PKS +RI EN D LS ED +G + + Y F+ ++ +
Sbjct: 265 PKSNNLSRISENFDCL-VELSPEDHAALGQLMGSNGEKAVRNLETKEYLGFDNFNEDFEE 323
Query: 551 P 553
P
Sbjct: 324 P 324
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 95.9 bits (228), Expect = 8e-19
Identities = 52/151 (34%), Positives = 84/151 (55%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D V W+ +E G +++G+ N + TQ++ ++E G ++P+++QVE + + Q
Sbjct: 514 DSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQTD 573
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
LI+YC GI V+A SP S P + D+P L AIAE++G S +VL + + +GV
Sbjct: 574 LIEYCHERGIRVVAHSPL------SAPGLL-DEPVLAAIAEEYGLSPAGVVLAWNVTQGV 626
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
VPIP S + I EN+ L +E +I
Sbjct: 627 VPIPSSTTPSHIVENLAAAGQRLDAEACARI 657
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 95.5 bits (227), Expect = 1e-18
Identities = 46/148 (31%), Positives = 83/148 (56%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W MEE + G ++IG+SNF+ ++ + ++ P V Q+EVN Q +
Sbjct: 112 DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLA 171
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
++ G+ + A++PF +D ++P L I K+GKS Q++LR+L+++ ++ +
Sbjct: 172 ILRKEGVAIEAWAPFAEGKNDIF-----NNPVLTKIGAKYGKSAAQVILRWLVEQDIIVL 226
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
KSVK R+ +N+ +FDF L+ D +I
Sbjct: 227 AKSVKPERMAQNLAIFDFELTEADKEEI 254
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 95.1 bits (226), Expect = 1e-18
Identities = 51/155 (32%), Positives = 86/155 (55%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+ W+ + E + GL +SIG+SNF I R++ + P + Q+E++ L Q +L +
Sbjct: 116 YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAW 175
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ IV ++SP + D+ + + +K+GK+ Q+V+R+ I G++ IP
Sbjct: 176 NATHNIVTESWSPLAQGGENVF-----DNQLVQHLTQKYGKTPAQVVIRWHIDNGMIVIP 230
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS +RI+EN DVFDF L ED+ + T + KR
Sbjct: 231 KSTTLSRIKENFDVFDFKLEKEDLTAMTTLDIGKR 265
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 94.7 bits (225), Expect = 2e-18
Identities = 53/164 (32%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
+DTWK MEE GL ++IG SNF I++IL+ I+P + E + +L Q +D+
Sbjct: 173 IDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFH 232
Query: 197 KRNGIVVMAFSPF---GPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
K+ I V+A SP P + D PSI D+ V +AE +V Q +L + Q+G +
Sbjct: 233 KKENIKVIAASPLANTNPTYGDKYPSILHDE-FWVKLAEDKNATVAQTILAWGQQRGTIV 291
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
I KS N I EN+ + ++ ++ +K+ R + W
Sbjct: 292 ISKSTHSNHIAENLCSQGIEFTKSELEEVAKQDKKLRLLNPIHW 335
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 94.7 bits (225), Expect = 2e-18
Identities = 53/161 (32%), Positives = 89/161 (55%), Gaps = 3/161 (1%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGL-AKSIGISNFNTTQIDRIL--ENGQIKPSVLQVEVNLHLG 172
D D++DTW+ +++ G K+IG+SNFN ++D++L E + P + Q+E + L
Sbjct: 127 DDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLT 186
Query: 173 QDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
Q L DY K I + A+SP G H +++ + + IA+KH + Q+++ + +Q
Sbjct: 187 QPDLFDYLKSKDIYITAYSPLG---HADASTLK--NKVVTDIAKKHNANAGQVLISWGVQ 241
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
+G + IPKS RI +NI F LS ED + + KE+
Sbjct: 242 RGTIVIPKSTTDERIIDNIKT--FTLSQEDFDALNNLEKEE 280
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 93.9 bits (223), Expect = 3e-18
Identities = 57/177 (32%), Positives = 91/177 (51%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+TW+GME +GL +SIG+SNF++ +I +L+ + PSV QVE++ Q KL C+
Sbjct: 139 ETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCE 198
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
N I V +SP G + + + P + +IA KH + Q+ LR+ + KG I KS
Sbjct: 199 ENNIHVSGYSPLGGPGNCWGSTAVIEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKS 258
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEKSDQVHDN 550
R+ EN + L +D++ I + K G F + P++ Q+ DN
Sbjct: 259 FNGARMIENKRALEIKLDDQDLSLIDHLEEWKIMRG-DFLVNQTTSPYKSIQQLWDN 314
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 93.9 bits (223), Expect = 3e-18
Identities = 54/156 (34%), Positives = 87/156 (55%), Gaps = 1/156 (0%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+T M + GL + IG+SNF+ + +DR + QV+ + + Q KL+DYC+
Sbjct: 117 ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCR 176
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK-GVVPIPK 376
+ +++ A+SP + + DDP LV I K+GKS Q+ LR+L+Q+ GV IPK
Sbjct: 177 IHDVLLTAYSPL------ARGGVL-DDPALVQIGNKYGKSPAQVALRWLVQQDGVAAIPK 229
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV 484
+ + +E N+ VFDF L+ +M +I +K K V
Sbjct: 230 ASSREHLEANLAVFDFELTDAEMERIRDPSKVKTGV 265
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 93.5 bits (222), Expect = 5e-18
Identities = 52/152 (34%), Positives = 85/152 (55%), Gaps = 3/152 (1%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+D L+T+ MEE + GL + IG+SNF+ Q++RI N +IKP QVE N++ L+
Sbjct: 132 IDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLL 191
Query: 188 DYCKRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG-- 358
YC+ + I +MA + G P + +DP + +A + K+ QI L++L QK
Sbjct: 192 SYCESHNIYLMAHTTIGHPPLKGPFGTSLLEDPVVKQVASEAKKTSAQICLKFLQQKSKM 251
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
+ IP S+ I+ N ++ DF L+ + M K+
Sbjct: 252 YILIPMSMNPKNIKSNYEL-DFTLTEQQMKKL 282
>UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative;
n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase
(GCY1), putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 274
Score = 93.5 bits (222), Expect = 5e-18
Identities = 51/146 (34%), Positives = 88/146 (60%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
DY +TW+ MEE G K+IG++N++ ++ + + + P+V QVE++ L Q L +
Sbjct: 106 DY-ETWRQMEEIYKAGKVKAIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKE 164
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+C ++GI++ A+SP G + P + DP + +A+K+G S +++ Y + +GVV +
Sbjct: 165 WCDKHGILLEAYSPLG---SEGAPLM--SDPAIQEMAKKYGVSPATVLISYHVNRGVVVL 219
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMN 448
PKS ++NRI N V LS EDM+
Sbjct: 220 PKSTQENRILSNRQVIP--LSPEDMD 243
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 93.1 bits (221), Expect = 6e-18
Identities = 45/148 (30%), Positives = 87/148 (58%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
+W+ +EE + G ++IG+SN+ + +L++ ++ P+VLQVE + L Q+ L CK
Sbjct: 135 SWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQVEFHPKLLQNDLRGLCKI 194
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
G+ A+S G + +P ++ IA++ G++ Q++LR+ +Q+ + +PKS
Sbjct: 195 RGVCFQAYSSLGT-------GLLLSNPVVLEIAKECGRTPAQVLLRWAVQQSIAVLPKSS 247
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFN 466
+ R++EN +FDF +S EDM ++ +
Sbjct: 248 QPERVKENGRLFDFEISEEDMERLSALD 275
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 93.1 bits (221), Expect = 6e-18
Identities = 49/139 (35%), Positives = 86/139 (61%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
++ ME G+ + IGISNF +++ ++ P++ Q E +L L Q L + K
Sbjct: 118 YRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLLQQKPLREAMKSK 177
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
++ ++SPF L ++PTL +IA+K+ K+ Q+VLR+LI++G+ IPK+ K
Sbjct: 178 KTLLQSWSPFIAGKGSIL-----ENPTLKSIAQKYNKTPAQVVLRFLIEQGISVIPKTSK 232
Query: 386 KNRIEENIDVFDFNLSSED 442
+ R++EN++VFDF+LS++D
Sbjct: 233 RARMQENLNVFDFSLSAQD 251
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 93.1 bits (221), Expect = 6e-18
Identities = 53/156 (33%), Positives = 88/156 (56%), Gaps = 11/156 (7%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRIL--------ENGQIKPSVLQV---EVNLHLG 172
WK + EA+ G +S+G+SN+ +D + E G+ + V+ V E++ L
Sbjct: 161 WKALVEAQEEGKIRSLGVSNYGVHHLDEMEVYMKELEEERGKGRGGVIDVGQWELHPWLA 220
Query: 173 QDKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQ 352
+ +I +C++ GIV A+SP + R D L + +K+ K+ QI+LR+ +Q
Sbjct: 221 RSDIISWCQQRGIVAEAYSPL-------IRGERHDSKLLQPLTKKYNKTPAQILLRWSLQ 273
Query: 353 KGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGT 460
KG VP+PK+V RI+EN D+FDF L++E+M + T
Sbjct: 274 KGFVPLPKTVTPGRIKENADIFDFELTAEEMEGLET 309
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 92.7 bits (220), Expect = 8e-18
Identities = 51/153 (33%), Positives = 83/153 (54%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W EE +LGLAK +G+SNFN I +L +IKP V Q+E+++ Q L+++ K+
Sbjct: 137 WAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKV 196
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
I +AFSP +++ + + TL IA+K SV Q+++ ++ + VV IP++ K
Sbjct: 197 NIYPVAFSPMA-KYNEVV-----KNETLNQIAQKQNASVAQVMIAFMYHQDVVVIPRTAK 250
Query: 386 KNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV 484
R++ N D S ED+ + N R V
Sbjct: 251 IERLQHNFDAQKLQFSEEDIQTLRNLNSNTRVV 283
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 92.7 bits (220), Expect = 8e-18
Identities = 52/151 (34%), Positives = 80/151 (52%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D V +TW+ EE G K+IG+SNF +D + E ++KP+V Q+++NL
Sbjct: 123 DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQIQINLKEPNKN 182
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
L+ K I +A+ P H L I + + KS QI+L+Y IQ+GV
Sbjct: 183 LLAVLKDEEITPVAWGPMKAEAHQK--------EALDEIGKIYHKSGAQILLKYQIQRGV 234
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
+ IPKS + N+++FDF L++ED+ KI
Sbjct: 235 IVIPKSHNRENQASNLELFDFELTAEDIEKI 265
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 92.7 bits (220), Expect = 8e-18
Identities = 52/156 (33%), Positives = 85/156 (54%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
+ ++++ ME G ++IG+SNF ++ +LE ++ P+V Q+E++ L QD+L
Sbjct: 135 FTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQL 194
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
R GI A+SP G + + DP ++ +A H +S QI+LR+ +Q G V IP
Sbjct: 195 HDRLGIRTEAWSPLG---RGQVLA----DPVVLELAAAHRRSAAQIILRWHVQLGNVVIP 247
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
K+ RI EN+DVF F L +M + + RT
Sbjct: 248 KASSYARIRENLDVFGFTLDPAEMAALAALERGHRT 283
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 92.3 bits (219), Expect = 1e-17
Identities = 51/143 (35%), Positives = 85/143 (59%), Gaps = 1/143 (0%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ-IKPSVLQVEVNLHLGQDKLIDYCK 199
TW + + K G +SIG+SNF + +L+N + I P+V QVE++ H Q++LI YC
Sbjct: 137 TWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCN 196
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
GI + A+S G + +L +R +P ++ IA + S +++L + +Q+G+ IPK+
Sbjct: 197 EKGIHIQAYSSLGTSGNINL--LR--NPIVLKIASQLNVSSARLLLNWALQQGIGVIPKA 252
Query: 380 VKKNRIEENIDVFDFNLSSEDMN 448
V K I++NI + DF + E MN
Sbjct: 253 VNKEHIKDNIQL-DFLIDEESMN 274
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 92.3 bits (219), Expect = 1e-17
Identities = 51/154 (33%), Positives = 88/154 (57%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+Y ++ +E ++IG+SNF +I + QIKP V Q+E+N + +
Sbjct: 114 NYYKAYQDLERLYKENKVRNIGVSNFWDNRIIDLCFFNQIKPMVNQIEINPFHQRIEDRF 173
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
Y + +V A++PF + + PTLV I +K+ K+ Q++LR+L+Q VV +
Sbjct: 174 YNDKYKVVSQAWAPFAEGKNGLFTN-----PTLVEIGKKYNKTPAQVILRWLVQSNVVAL 228
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
K+V ++R++EN D+FDF LS +D++KI NK+
Sbjct: 229 CKTVNESRMKENFDIFDFELSKQDLDKIVALNKQ 262
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 92.3 bits (219), Expect = 1e-17
Identities = 51/146 (34%), Positives = 81/146 (55%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
LD W+ ME G AK+IG+SNF + IL I P V Q++ L + K+ +
Sbjct: 128 LDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFS 187
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
+ + ++V A+SP + + D+P + A A+K+G SV Q+ LR+++Q GV+P+PK
Sbjct: 188 EEHAMLVEAYSPL------ATGGVL-DNPQVQAYADKYGVSVAQLALRFVLQNGVLPLPK 240
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKI 454
+V IE N + DF +S DM +
Sbjct: 241 AVNPAHIEANTQL-DFAISVADMQAL 265
>UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Bacteroides fragilis|Rep: 2,5-diketo-D-gluconic acid
reductase - Bacteroides fragilis
Length = 298
Score = 92.3 bits (219), Expect = 1e-17
Identities = 47/153 (30%), Positives = 86/153 (56%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y D W M K G + IG+SNF+ ++++ G+ PS+ Q+ V+ + + ++Y
Sbjct: 139 YEDIWDVMMRLKKEGKVRYIGVSNFHINHLEKLKSIGEC-PSINQIYVSPLSIKHEDLEY 197
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
N I +M +SP + H L +D L+ +AEK+ K+ Q++LR+ I +G +P+P
Sbjct: 198 SINNAIQLMTYSPLMDLVHGQL-----NDNILMPLAEKYRKTKHQVILRWNIDRGCMPLP 252
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
++ NR+ N ++FDF L+ E++ I N++
Sbjct: 253 RTTNPNRLLGNFELFDFKLTEEEIEAISAMNRD 285
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 91.9 bits (218), Expect = 1e-17
Identities = 48/152 (31%), Positives = 83/152 (54%), Gaps = 1/152 (0%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQD- 178
++ D WKG+E K G A+SIG+SNF ++ ILE + P++ Q+E + +L +
Sbjct: 121 NLTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLEYHPYLQRSH 180
Query: 179 KLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
I + + GI V +F P+ ++ P D L +IA KH + + +VL ++I +
Sbjct: 181 DFIPWMRERGIEVSSFKTLAPV---TVGKGGPLDEPLASIAAKHNITTSAVVLNWVISQN 237
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
+VPI + K+ R+EE I L E++++I
Sbjct: 238 IVPITTTTKRERMEEYIAAISLQLDREELDEI 269
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 91.9 bits (218), Expect = 1e-17
Identities = 49/156 (31%), Positives = 84/156 (53%), Gaps = 4/156 (2%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVN--LHLGQDKLIDYCK 199
WK ME A GL S+G+SNF ++ +L+ I P V Q+E + ++ L+++C+
Sbjct: 125 WKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQ 184
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
GI+V + P P+ D+ + +L K+ S TQI+L++ KGV+PI +
Sbjct: 185 SKGIIVEGYGPLSPLVRDAQGPVAEFTKSL---ESKYHVSDTQILLKWAYSKGVIPITTT 241
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKE--KRT 481
K R++E ++ F L D++++GT + KRT
Sbjct: 242 SKIERMKECLNFDSFTLDKADIDELGTLGVQHHKRT 277
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 91.5 bits (217), Expect = 2e-17
Identities = 52/148 (35%), Positives = 82/148 (55%), Gaps = 5/148 (3%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ--IKPSVLQVEVNLHLGQDKLIDY 193
+ W +E GL + IG+SNFN Q+ + ++ + I+P+ Q+E + D L+ Y
Sbjct: 135 ECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKY 194
Query: 194 CKRNGIVVMAFSPF---GPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
+ G+ V A+SP G +F + + LV +A+K+G + Q+VLR+ +Q+ VV
Sbjct: 195 SQSKGLTVTAYSPLAQGGELFENEI---------LVGLAKKYGVTPAQVVLRWNVQRDVV 245
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMN 448
IPKS RI N D+F F LS EDM+
Sbjct: 246 VIPKSTSAKRIASNADLFGFELSDEDMD 273
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 91.5 bits (217), Expect = 2e-17
Identities = 51/147 (34%), Positives = 84/147 (57%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
+LDTW+GM +A+ GL +SIG+SNF + +++ + P+V QVE++ + Q L +
Sbjct: 118 WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAF 177
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+GI ++SP + S + L +A +G + TQ+VLR+ +Q G PIP
Sbjct: 178 HDEHGIRTESWSPL------ARRSELLTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIP 231
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
KS +R EN DVF F L+++ ++ I
Sbjct: 232 KSADPDRQRENADVFGFALTADQVDAI 258
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 91.1 bits (216), Expect = 2e-17
Identities = 46/141 (32%), Positives = 82/141 (58%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
DTWK + ++ G+A+++G+ NF + R+ E P+V Q+E++ Q +++ +CK
Sbjct: 131 DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCK 190
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+GI V A+SP + D T+ IA H S Q++LR+ I+ G + IPKS
Sbjct: 191 EHGIAVEAYSPMA-----RGADLNAGDGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKS 245
Query: 380 VKKNRIEENIDVFDFNLSSED 442
V +R +EN+++F F L++++
Sbjct: 246 VHADRQKENLNLFGFALTADE 266
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 91.1 bits (216), Expect = 2e-17
Identities = 57/155 (36%), Positives = 92/155 (59%), Gaps = 6/155 (3%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRI-LENG-QIKPSVLQVEVNLHLGQDK 181
+D L+TWK MEE NLGLAK IG+SNF+ Q++R+ + G +I+P QVE +++L Q
Sbjct: 131 IDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQP 190
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRP--DDPTLVAIAEKHGKSVTQIVLRYLIQK 355
++DY + + +++++ G P P DP L +A++ GK+ Q LR+L++
Sbjct: 191 MLDYLTQRKMYMISYTCLGRATLKG-PYGYPLLQDPVLNEVAKEIGKTPAQTNLRFLLKL 249
Query: 356 G--VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
V IPKS+ I+ NI + DF+L+ E K+
Sbjct: 250 SPYAVVIPKSLNPANIKGNISL-DFDLTQEQFEKL 283
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 90.6 bits (215), Expect = 3e-17
Identities = 52/151 (34%), Positives = 85/151 (56%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TW+ ME+ G K+IG+SN++ +D++L +I P+ QVE++ L Q +L+ YC
Sbjct: 173 TWELMEKLPATGKTKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHD 232
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
GI+ A+SP G L D + +IA+ H Q+V+ + Q+GVV +PKSV
Sbjct: 233 KGILPQAYSPLGSSGGPVL-----QDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSV 287
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
+RIE N + LS E+M ++ +K++
Sbjct: 288 TPSRIETNGKL--IVLSDEEMLELNELHKQE 316
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 90.2 bits (214), Expect = 4e-17
Identities = 53/158 (33%), Positives = 84/158 (53%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
++ + M E + G A SIG+ NF +D + + G P+V Q+E++ Q +
Sbjct: 124 FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAGHT-PAVNQIEIHPGFSQAEQRSD 182
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ GIV A+SP G DPT+ IA +HG SV Q ++R+ IQ+G V IP
Sbjct: 183 NRDRGIVTEAWSPLGQ-------GQNLTDPTIAKIAAEHGVSVAQAIIRWHIQRGDVVIP 235
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
+S K R+ +N DVF F LS+++++ I + E +G
Sbjct: 236 RSSKVERVRQNFDVFGFELSADEVSAIEALDVEDGRIG 273
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 90.2 bits (214), Expect = 4e-17
Identities = 49/138 (35%), Positives = 82/138 (59%), Gaps = 6/138 (4%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y +TW+ ME+ + G AK+IG+SNFN + RILE +I+P+V QVE + + Q +L+ +
Sbjct: 119 YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAF 178
Query: 194 CKRNGIVVMAFSPFG--PMF----HDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
C++ I +MA P G P+ H +P D + IA + G + Q++L + +Q+
Sbjct: 179 CEKEHIHLMAHQPLGGKPVGVVAPHADIPG-PLFDTKIAQIAAQTGMTPAQVILSWAVQR 237
Query: 356 GVVPIPKSVKKNRIEENI 409
G IPK+ ++R+ EN+
Sbjct: 238 GTSIIPKTSNESRLSENL 255
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 90.2 bits (214), Expect = 4e-17
Identities = 48/151 (31%), Positives = 82/151 (54%), Gaps = 1/151 (0%)
Frame = +2
Query: 5 IVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKL 184
+ D +T+ + + GL IG+SNF+ ++ + + + Q+E + + G ++L
Sbjct: 121 LADMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEEL 180
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLI-QKGV 361
+ +C+ N + V A+SP +D L +I +++GKS Q+ +R+LI Q+ V
Sbjct: 181 VRFCQDNDVTVTAYSPLA-------EGRAVEDDVLRSIGDRYGKSAAQVSIRWLIQQENV 233
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
V IPK+ IE NIDVFDF L+ DM +I
Sbjct: 234 VTIPKAATPKHIEANIDVFDFELTDRDMRRI 264
>UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 274
Score = 89.8 bits (213), Expect = 6e-17
Identities = 50/161 (31%), Positives = 92/161 (57%), Gaps = 2/161 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIK--PSVLQVEVNLHLGQDKL 184
D++DTW+ M++ + +++G+SNF ++R+L + K P+V Q+E++ KL
Sbjct: 105 DFVDTWREMQKLMDTNKIRNLGVSNFGIKNLERLLNDPSCKIVPAVNQIELHPGNPSPKL 164
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
I YC GI +SP G DS P + + T+ +IA+ +SV Q++L + ++KG
Sbjct: 165 IAYCAEKGIHCSGYSPLGSS--DS-PLYKNE--TIASIAKAKNRSVQQVLLMWGVKKGWS 219
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVG 487
+PKSV +R++ N D+ ++L+ E++ KI + + G
Sbjct: 220 VLPKSVNPDRVKANFDLDGWDLTDEEVAKIDSIPDRFKVCG 260
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 89.8 bits (213), Expect = 6e-17
Identities = 47/131 (35%), Positives = 78/131 (59%), Gaps = 2/131 (1%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
DTW +E+ + G +SIG+SNF +I+ +L+ +I P+V Q+E + +L Q L Y K
Sbjct: 160 DTWAALEKLVDAGKVRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLK 219
Query: 200 R--NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
I+ +A+SP G +++ P + DDPT+ IA+K K +++ + +Q+G +P
Sbjct: 220 EKVTNILSVAYSPLGNNIYNA-PRV-VDDPTVKEIAQKLNKDPAALLISWAVQRGTSVLP 277
Query: 374 KSVKKNRIEEN 406
KSV +RIE N
Sbjct: 278 KSVTPSRIESN 288
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 89.4 bits (212), Expect = 7e-17
Identities = 49/152 (32%), Positives = 83/152 (54%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++ W+ + EAK G +SIG+ NF ++R+ + P++ Q+E++ Q+ +
Sbjct: 119 YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKW 178
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ + I ++SP +D L D P L +A H ++V+QI+LR+ Q + IP
Sbjct: 179 HQEHQIATESWSPLART-NDVL-----DHPVLQKLASNHNRTVSQIILRWHYQLDAIAIP 232
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
KS +R ENI +FDF LS E+M+ I +K
Sbjct: 233 KSATPSRQLENISIFDFELSDEEMSIINQLSK 264
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 89.4 bits (212), Expect = 7e-17
Identities = 61/160 (38%), Positives = 83/160 (51%), Gaps = 19/160 (11%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DYLDTW+ ME LG+ +SIG+SNFN QI RI++ KP V QVE+ Q L+
Sbjct: 155 IDYLDTWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLV 214
Query: 188 DYCKRNG-IVVMAFSPFGPMFHDSLPSI----RPDDPTLVAIAEKHGKSVT--------- 325
DYC+ NG F+ + SLPS+ R + L + + K V
Sbjct: 215 DYCRYNGNYCDSLFTSWSTKQKKSLPSVFLFGRCETDWLRSTSALQVKLVAIFGSIFISI 274
Query: 326 ----QIVLRYL-IQKGVVPIPKSVKKNRIEENIDVFDFNL 430
I +R L I GVVPIPK+ I+EN+++FDF L
Sbjct: 275 RLNLNINIRILEIDYGVVPIPKAANPIHIKENLNIFDFKL 314
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 89.0 bits (211), Expect = 1e-16
Identities = 48/147 (32%), Positives = 82/147 (55%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++ W+ + +A+ G +SIG+SNF I+ + + P + QVE++ + Q + Y
Sbjct: 136 YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVELHPYFNQAEQRAY 195
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ I+ MA+SP G +I DD L IA++ ++V Q+VLR+ +Q GV+PIP
Sbjct: 196 DESQQIITMAWSPLG-----RAKAIL-DDAVLKQIAQETSRTVVQVVLRWQVQMGVIPIP 249
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
K+ N +FDF+LS + + +I
Sbjct: 250 KAASDQNQMANQAIFDFSLSDDQVQRI 276
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 89.0 bits (211), Expect = 1e-16
Identities = 57/166 (34%), Positives = 92/166 (55%), Gaps = 25/166 (15%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
WK ME LGL ++IG+SNF QI +L+ +I P+V QV+++ QD+L+ +C+
Sbjct: 149 WKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSK 208
Query: 206 GIVVMAFSPFGPMFHDSLPSIR----PDDP--------------------TLVA-IAEKH 310
GI V A +P G PS D+P ++VA IA++H
Sbjct: 209 GIHVSAHTPLGVPASGPGPSDSGSGGEDEPGTPRISFRRSRSVHGPMLKLSVVAEIADRH 268
Query: 311 GKSVTQIVLRYLIQKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMN 448
K+ Q++LR+ +Q+G +P S+K +RI +NID+F ++LS ++ N
Sbjct: 269 KKTPEQVILRWGLQRGTSVLPCSLKADRIRKNIDIFSWSLSDDECN 314
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 89.0 bits (211), Expect = 1e-16
Identities = 48/155 (30%), Positives = 82/155 (52%)
Frame = +2
Query: 35 MEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 214
+EEAK G +SIG+SN+ ++ + ++ P Q+E + H + L YCK I
Sbjct: 145 LEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIF 204
Query: 215 VMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVKKNR 394
AFS H+ P + +DP +V +A+KH SV ++L + +++ V +PKSV +R
Sbjct: 205 FQAFSSLAR--HE--PKLI-EDPVVVELAKKHNTSVPLVLLAWALRQNVGIVPKSVTPSR 259
Query: 395 IEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
I EN V D L+ ED+ + ++ + + + W
Sbjct: 260 IVENFKVIDIALTPEDIQSLTALDRGQHYIRCTGW 294
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 88.6 bits (210), Expect = 1e-16
Identities = 52/155 (33%), Positives = 77/155 (49%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y D+W+ ME + L KSIG++NF + +L KP + QVE + L Q+ L Y
Sbjct: 119 YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKY 178
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
I A+SP I +P + IA+KH SV Q++L++ + + + P
Sbjct: 179 LAEQNIAHAAWSPLAK-------GILMQNPVITEIAKKHQASVDQVILQWHLNRNTIIFP 231
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS+ +RIEEN + F L + DM KI KR
Sbjct: 232 KSITSSRIEENSRLSYFQLDASDMEKIDRLETGKR 266
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 88.6 bits (210), Expect = 1e-16
Identities = 52/159 (32%), Positives = 87/159 (54%), Gaps = 4/159 (2%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNF---NTTQIDRILENGQIK-PSVLQVEVNLHLGQD 178
D +K + EA+ G KSIGISNF + ++++ + P + Q+E + + +
Sbjct: 115 DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEK 174
Query: 179 KLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
+ G+ + A+ P G + +P+ LV IA KH KSV Q+VLR+++Q
Sbjct: 175 VARQLHDKYGVQIEAWGPLGRTANKYDTFHQPE---LVEIAAKHDKSVGQVVLRWIMQSN 231
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
++ + KSV +R+ ENID+F+F L +DM KI T +K +
Sbjct: 232 IITVAKSVNPSRMAENIDIFNFELDDDDMKKIETLDKNE 270
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 88.2 bits (209), Expect = 2e-16
Identities = 49/148 (33%), Positives = 83/148 (56%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
+W +EE G K+IG+SN+ I +L + ++ P+VLQ+E L Q +L D C
Sbjct: 133 SWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCME 192
Query: 203 NGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSV 382
GI A+S G +L +R +P ++ I G++ Q++LR+ +Q+G+ +P+S
Sbjct: 193 TGIHFQAYSSLGK---GAL--LR--EPEVMDIVRHCGRTPAQVLLRWALQQGISVLPRSS 245
Query: 383 KKNRIEENIDVFDFNLSSEDMNKIGTFN 466
+ +R+ EN VFDF L+ DM ++ N
Sbjct: 246 QPSRVLENAQVFDFKLNETDMKRLDDLN 273
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 88.2 bits (209), Expect = 2e-16
Identities = 48/146 (32%), Positives = 80/146 (54%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
++ + +E+A+ G +SIG+SNF ++ IL+N + KP+ Q+ ++ L+DYC
Sbjct: 135 VEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYC 194
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
K+ I+ A+SP H L DP ++ +A+K+ S QI +RY ++ G+V +PK
Sbjct: 195 KKQNILAEAYSPIA---HGELLK----DPRVIELAKKYNVSPAQICIRYTLELGLVSLPK 247
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKI 454
S I EN V DF S D+ +
Sbjct: 248 SKTPKYIAENAQV-DFTFSKADLQTL 272
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 87.8 bits (208), Expect = 2e-16
Identities = 48/152 (31%), Positives = 85/152 (55%), Gaps = 9/152 (5%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILE---NGQIKPSVLQVEVNLHLGQDK--LID 190
W + +AK G + IG+SNF+ ++R + N P V Q+E + +L +I
Sbjct: 153 WAEVIDAKKAGKVRHIGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSPGIIK 212
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAI----AEKHGKSVTQIVLRYLIQKG 358
+ + N I++ A+ P +F + +D L + AEK+GK+ QI+LRY +QK
Sbjct: 213 FAQENDILIEAYGPLSTLFRIKQNGVDVEDHPLKELIPKLAEKYGKTDAQILLRYTLQKK 272
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
++PI S K +RI ++++V++F +S ED+ +I
Sbjct: 273 ILPITTSSKLDRIRQSLEVYNFEISDEDVAEI 304
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 87.4 bits (207), Expect = 3e-16
Identities = 49/156 (31%), Positives = 83/156 (53%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V +T + A+ +GL + IG+SNF I++ + QVE + +L Q K+
Sbjct: 111 VPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAKVR 170
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
C ++G+ ++A+SP + I+ D TL I H K+ Q+ LR+L+Q+ V
Sbjct: 171 AACDQHGLALVAYSPI------ARGRIKTDQ-TLAGIGRAHRKTPAQVCLRWLVQQNVAA 223
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
IP++ + R+ ENI++FDF LS ++M +I K
Sbjct: 224 IPRTSRIERLSENIEIFDFELSDDEMARIAALANPK 259
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 87.4 bits (207), Expect = 3e-16
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 9/160 (5%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
L+ W+ + E + G A+SIG+SNFN + ++ I G P Q+E++ + L+ Y
Sbjct: 162 LEQWRALLELQANGKARSIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYM 221
Query: 197 KRNGIVVMAFSPFGPMF----HDSLPSIRPDD-----PTLVAIAEKHGKSVTQIVLRYLI 349
++ I +A+S P+ + S + D+ T +AEK+G S Q++LR+ +
Sbjct: 222 DQHAIAPIAYSSLVPLSTWRTKEGQASAKTDEMKAAGTTFRDMAEKYGVSEAQLLLRWGV 281
Query: 350 QKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
Q G +PKS+ +R+ +NID+F F++ DM K+ T ++
Sbjct: 282 QNGYAVLPKSMNPDRMRQNIDLFSFSIDDTDMAKMATMDQ 321
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 86.2 bits (204), Expect = 7e-16
Identities = 50/169 (29%), Positives = 84/169 (49%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V +T K + + G ++IG+SNF + Q++ + + + QVE + +L L
Sbjct: 115 VPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLK 174
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+ G+ + A+SP DP L+ I HGK+ Q+ LR++IQ+G++
Sbjct: 175 AKADQLGVSITAWSPLAQ-------GKVAQDPVLIEIGRAHGKTPGQVTLRWIIQQGIIA 227
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPY 514
IP++ RIEEN D+ DF LS ++M +I + +G W D Y
Sbjct: 228 IPRTSNPKRIEENFDILDFELSEKEMAQIHGLARPDGRIG--DWIDRAY 274
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 86.2 bits (204), Expect = 7e-16
Identities = 45/154 (29%), Positives = 87/154 (56%), Gaps = 3/154 (1%)
Frame = +2
Query: 20 DTWKGMEEA---KNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+TW ME+ + G K+IG+SNF+ ++ + + ++ P+V Q+E + +L + +L+
Sbjct: 145 ETWAKMEDVFLNSHKGKVKAIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVK 204
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
YCK I V A+SP G ++ S+ +D L IA+KH + + L + +Q+G
Sbjct: 205 YCKHKSIHVTAYSPLG-QYNASI----HEDKDLNEIAKKHDVTAATVALSWAVQRGTSVA 259
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
PKS + R+++NI + L+ E+M ++ +++
Sbjct: 260 PKSTNEKRMKQNITL--IKLTDEEMKQVDVISQD 291
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 86.2 bits (204), Expect = 7e-16
Identities = 53/149 (35%), Positives = 82/149 (55%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V +DTWK M + + G K+IG+SNF+ +D I+E + PSV Q+E + L Q +LI
Sbjct: 137 VSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELI 196
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+ K I + A+SP G + + P + IAEK+G + Q+++ + I G
Sbjct: 197 AHHKAKNIHITAYSPLGN--NTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSV 254
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
IPKSV +RI EN +LS ED++ +
Sbjct: 255 IPKSVTPSRIGENFK--QVSLSQEDVDAV 281
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 85.8 bits (203), Expect = 9e-16
Identities = 47/147 (31%), Positives = 85/147 (57%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+D WKG+ + G K+IG+SNF + I++ + P V Q++++ L + +
Sbjct: 127 YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQIQLSPDLARTEPRAV 186
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ GIV A+SP G +R + P ++ IA++ KS Q++LR+ +Q+ +VPIP
Sbjct: 187 HRLLGIVTEAWSPIGRS-----SGLRAN-PLIIEIAQRLDKSPAQVLLRWHVQQDIVPIP 240
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
++ ++EN+ VFDF+L++ +M I
Sbjct: 241 QASDPLWLKENLSVFDFSLTAGEMASI 267
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/155 (34%), Positives = 84/155 (54%), Gaps = 4/155 (2%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRI-LENGQIKPSVLQVEVNLHLGQD 178
D V +DTWK ME+ GL K IG+SN+ Q++R+ + + P QVE NL++ Q
Sbjct: 130 DGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYMQQG 189
Query: 179 KLIDYCKRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYL--I 349
L +Y + GI+V +S G P + + D L IA + GKSV ++ L++L I
Sbjct: 190 PLREYMHKEGIIVTGYSTLGTPDWAKPDEPVVLKDEELNKIAAETGKSVGEVELKFLLTI 249
Query: 350 QKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
+ G + KSV RI +N + DF L+ + + ++
Sbjct: 250 EPGASLLAKSVTPERIYKN-NHLDFELTKDQIQRL 283
>UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 276
Score = 85.0 bits (201), Expect = 2e-15
Identities = 47/152 (30%), Positives = 80/152 (52%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
+++W+ + + + G IG+SN+N ++ I+ G P++ QVE + + + YC
Sbjct: 119 IESWRALLQHQKEGRINKIGVSNYNIHHLEEIISLGLPLPAINQVEFSAFNNRPTFLSYC 178
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
+GI+V AFSP R D L+ ++ K+ K+ I+LRY +QKGV PI K
Sbjct: 179 FNHGILVQAFSPL-------TRGYRLSDIRLLDLSLKYNKTPANILLRYCLQKGVSPIFK 231
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
+ I EN+ F L DM+ + T+++E
Sbjct: 232 ASSFVHIHENVKAEQFMLDPSDMDVMDTWDEE 263
>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
lacusprofundi ATCC 49239
Length = 665
Score = 85.0 bits (201), Expect = 2e-15
Identities = 44/143 (30%), Positives = 82/143 (57%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W+ +E G A+++GI N + Q++ +LE G+I P+++QVE + + ++ L++ C
Sbjct: 520 WRNLEAVHERGWARTLGICNVSRAQLETVLETGEIDPALVQVERHPYRPRNGLVELCHGR 579
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
GI V+A SP S P + D+P L AI + G S ++V+ + +GVVPIP S
Sbjct: 580 GIRVVAHSPL------SAPGLL-DEPVLNAIGTERGLSPAEVVIAWNASQGVVPIPSSTA 632
Query: 386 KNRIEENIDVFDFNLSSEDMNKI 454
++ + N+ L+++++ +I
Sbjct: 633 ESHVVSNLAAGSERLTADEVARI 655
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/177 (27%), Positives = 89/177 (50%), Gaps = 11/177 (6%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
+++ TW+ +E + GL + IG SN ++ +L + +++P+V ++E++ H Q L D
Sbjct: 156 EFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFD 215
Query: 191 YCKRNGIVVMAFSPFG----PMFHDSLPSIRP-DDPTLVAIAEKHGKSVTQIVLRYLIQK 355
Y + IV + + P G P + P +DP + IA HG + L++ +Q+
Sbjct: 216 YVRVRNIVPVGYCPLGSPGRPERDRTAEDTSPLEDPVIQRIAAAHGMHPAAVCLKWAVQR 275
Query: 356 GVVPIPKSVKKNRIEENI----DVFDFNLSSEDMNKIGTFNKEKRTV-GMSF-WQDH 508
G PIP S K+ I N+ V LS ++M I ++ R + G F W+++
Sbjct: 276 GQTPIPFSTKRRNIHANLAAAASVTTAPLSEQEMADIAATDRHCRLIKGQVFLWKEN 332
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 84.6 bits (200), Expect = 2e-15
Identities = 55/167 (32%), Positives = 82/167 (49%), Gaps = 10/167 (5%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V DTW+ ME+ GL K IG+SN+ + +L +IKP V Q+E++ D +
Sbjct: 131 VPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATV 190
Query: 188 DYCKRNGIVVMAFSPFGPMFHD------SLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLI 349
+C NGI V A+SP G + D + ++ + TL AIA+ G S + L + +
Sbjct: 191 KFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKAIADAKGTSPHCVALAWHV 250
Query: 350 QKGVVP----IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
+K IPKS RIE N + LS +DM+ I + KR
Sbjct: 251 KKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKR 297
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 84.6 bits (200), Expect = 2e-15
Identities = 48/155 (30%), Positives = 82/155 (52%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+ W+ + K GL +SIG+ NF+ + R+++ I P+V Q+E++ L Q +L +
Sbjct: 116 YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAW 175
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ I ++SP D + +A+++ K+ QIV+R+ + G++ IP
Sbjct: 176 NATHHIATESWSPLAQGGKGVF-----DQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIP 230
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KSV RI EN +VFDF L E++ I + KR
Sbjct: 231 KSVTPARIRENFEVFDFKLQKEELLAITKLDCGKR 265
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/155 (32%), Positives = 80/155 (51%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D W+ ME A+ G KSIG+SN T + + + P+V QVE N + Q L
Sbjct: 115 DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQ 174
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ + A++P G + +L +P + +A K+ K QI+LR+ Q+GV+
Sbjct: 175 LLAAQDVKLEAWAPLG-QGNQALFK----EPIIQQLAIKYHKDAGQIILRFEHQEGVIVF 229
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEK 475
PKSV RI+ N D+FDF L+S +M ++ + K
Sbjct: 230 PKSVHSARIKSNRDIFDFELTSTEMAQLRALDTGK 264
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 84.2 bits (199), Expect = 3e-15
Identities = 43/159 (27%), Positives = 89/159 (55%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W ME+ + G AK+IG+SN++ + ++ L+ I P + Q+E + +L Q++L+ + +
Sbjct: 135 WAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREK 194
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
I + ++ P P+ P P DP + +A K+ + +++LR+ I +G V + S K
Sbjct: 195 DIKIASYGPLTPILR--APG-GPVDPKVSELAAKYKVTEGEVLLRWSIDRGDVAVTTSSK 251
Query: 386 KNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQ 502
++R++E + V F L+ E++ +I + + +FW+
Sbjct: 252 ESRLQEFLQVLTFQLTPEEVREISQLGQGRHY--RAFWR 288
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 83.8 bits (198), Expect = 4e-15
Identities = 52/145 (35%), Positives = 80/145 (55%), Gaps = 1/145 (0%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVN-LHLGQDKLID 190
Y++ ++G+ + GL ++IG SNF ++ + G + P V Q++++ HL D
Sbjct: 121 YVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQLDPYHLRPDITAI 179
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ + GIV ++SP G + L DP + IAE HGK+ QIVLR+ +Q G VP
Sbjct: 180 HAAK-GIVTESWSPIGRA-GEMLA-----DPAITRIAEAHGKTPAQIVLRWQVQSGFVPA 232
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDM 445
PKS R +N+DVF F L+ DM
Sbjct: 233 PKSADPERQAQNLDVFGFALTESDM 257
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 83.4 bits (197), Expect = 5e-15
Identities = 48/143 (33%), Positives = 73/143 (51%)
Frame = +2
Query: 26 WKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
W +E+A N G A++IG+SN+ ++ + E + P VLQVE + L Y +
Sbjct: 136 WPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQVESHPFFPNADLRAYAQGL 195
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
G+V A+SP DPTLV I + G TQ+ LR+ + +G V PK++
Sbjct: 196 GMVFEAWSPLAR-------GRAVTDPTLVEIGAELGVGPTQVTLRWALDRGHVVFPKTLS 248
Query: 386 KNRIEENIDVFDFNLSSEDMNKI 454
+ R+ N DVF F+L E +I
Sbjct: 249 RERMAANFDVFSFSLDPEQTARI 271
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 83.0 bits (196), Expect = 6e-15
Identities = 53/152 (34%), Positives = 80/152 (52%), Gaps = 2/152 (1%)
Frame = +2
Query: 35 MEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 214
+ E K G AK IGISN+N Q + + + +Q E + L QD ++ + ++
Sbjct: 120 LAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKTARGFDMM 179
Query: 215 VMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG-VVPIPKSVKKN 391
++SP G S P+I +AE+HGK+ QI+LR+ +Q+ V IPK+ K
Sbjct: 180 FTSYSPLGRGEAMSNPAIE-------RLAEQHGKTPAQIILRWHLQQANVAAIPKATSKA 232
Query: 392 RIEENIDVFDFNLSSEDMNKI-GTFNKEKRTV 484
IE+N D+FDF LS+ DM I G + R V
Sbjct: 233 HIEQNFDIFDFELSATDMKTIYGLMKPDGRMV 264
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 83.0 bits (196), Expect = 6e-15
Identities = 47/151 (31%), Positives = 80/151 (52%), Gaps = 1/151 (0%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+T+ +E + G +SIG+SN+ ++ +L +I P++ Q E + H +L +YCK
Sbjct: 135 ETYVELETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHFRNSELAEYCK 194
Query: 200 RNGIVVMAFSPF-GPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
GI A+S GP + ++L D + IA H S I+L + + +G +P+
Sbjct: 195 EKGIHFQAYSSLGGPSYVENLLK----DKIIKKIANAHSTSPAVILLAWGLNQGYSILPR 250
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
+ K RIEEN D LS ++M +IG+ +K
Sbjct: 251 TEKVGRIEENWKAKDIKLSEKEMKEIGSIDK 281
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 83.0 bits (196), Expect = 6e-15
Identities = 48/153 (31%), Positives = 81/153 (52%), Gaps = 4/153 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILEN-GQIKPSVLQVEVNL---HLGQ 175
V +T ME+ + G + IGISNF+ ++ + + + Q+E N+ +
Sbjct: 116 VSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEYNVATREIED 175
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
+ + D+C++NG+ ++A+SP H + TL I +K+GK Q+ L ++I+K
Sbjct: 176 EGIYDFCRKNGMAIIAYSPLS---HGKIFGNEMILETLTDIGKKYGKRPAQVALNWIIRK 232
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
G PIPK+ K + ENI+ DF LS EDM +
Sbjct: 233 GAFPIPKASKPIHMAENIESTDFTLSDEDMKTL 265
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 82.2 bits (194), Expect = 1e-14
Identities = 42/109 (38%), Positives = 64/109 (58%)
Frame = +2
Query: 5 IVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKL 184
++D WK MEE + LGL K+IG+SNF+ +++ +L I P+ QVEV+ + Q+KL
Sbjct: 139 MMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKL 198
Query: 185 IDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQI 331
++CK GI + A+SP G + D P L IA + GK++ QI
Sbjct: 199 REFCKEKGIQLCAYSPLGGKGTPWSNNAVMDCPLLKQIAMERGKTIAQI 247
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 81.8 bits (193), Expect = 1e-14
Identities = 54/182 (29%), Positives = 96/182 (52%), Gaps = 4/182 (2%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLID 190
D++ T+K +EE K G KSIG+SN + + R+L+ + P+V Q E++ +L Q K I+
Sbjct: 141 DWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIE 200
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIR-PDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+ +++GI+V AFSP G S +++ ++P V IA+KH S +++ + + +
Sbjct: 201 FNEKHGILVTAFSPLG----SSTGALKLHENPIAVEIAQKHNTSTGSVLINWHVSQKRAV 256
Query: 368 IPKSVKKNRIEENIDVFDFNLSSED-MNKIGTFNKEKRTVGMSFWQDH--PYYPFEKSDQ 538
+PK+ R+ N + D ++KI +R +G+ W D Y F + D
Sbjct: 257 LPKTRSIERVVANGMKVPLDQGDLDKLDKIWLQTGTQRAIGLR-WLDKNGDYLGFSEDDI 315
Query: 539 VH 544
H
Sbjct: 316 EH 317
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 81.8 bits (193), Expect = 1e-14
Identities = 55/188 (29%), Positives = 95/188 (50%), Gaps = 4/188 (2%)
Frame = +2
Query: 2 DIVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
D + +DTWK M + A+++G+SN ++ I+ + P+V Q+E + L ++
Sbjct: 143 DDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAIINATGVVPAVNQIERHPVLQSNE 201
Query: 182 LIDYCKRNGIVVMAFSPFGPM-FHDSLPSIRPDDPTLVAIAEKH-GKSVT--QIVLRYLI 349
LI+YC++ GI V A+S FG F L RP+ + A K G +VT Q++L +
Sbjct: 202 LIEYCQKKGIHVTAYSAFGNNGFGVPLLVTRPEVKEVAESASKRLGTTVTPAQVILAWSQ 261
Query: 350 QKGVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQDHPYYPFEK 529
G IPKSV +RI EN + L+ E++ K+ K++R + + P + +
Sbjct: 262 VGGHSVIPKSVTPSRIHENFK--EVELTPEEIAKVSELGKDRRRYNTPYVANTPRWDIDI 319
Query: 530 SDQVHDNP 553
+ + P
Sbjct: 320 FGEEEEKP 327
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 81.8 bits (193), Expect = 1e-14
Identities = 46/157 (29%), Positives = 96/157 (61%), Gaps = 3/157 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEA---KNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDK 181
DYL+T+K +E+ N ++IG+SNF+ ++R+++ ++KP+V QVE + HL Q +
Sbjct: 166 DYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQME 225
Query: 182 LIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
L +C + I++ A+SP G H + P+++ P + +AEK+ + +++ Y I++G
Sbjct: 226 LRKFCFMHDILLTAYSPLGS--HGA-PNLK--IPLVKKLAEKYNVTGNDLLISYHIRQGT 280
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
+ IP+S+ RI +I+ +L+ +++ ++ F ++
Sbjct: 281 IVIPRSLNPVRISSSIEF--ASLTKDELQELNDFGEK 315
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 80.6 bits (190), Expect = 3e-14
Identities = 46/147 (31%), Positives = 79/147 (53%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y+D ++GM E K GLAK+IG+SNF +D ++ G + P V Q++++ + ++ D+
Sbjct: 122 YVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQIQLDPSRPRLEVRDF 180
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ IV A+SP G L + P ++ A+KHG + VL + + +G+V IP
Sbjct: 181 LDNHDIVTEAWSPLGRGADGVL-----NAPAVLDAAKKHGITPAAAVLAWELNQGIVTIP 235
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
KS N++ LS+++M I
Sbjct: 236 KSANPEHQRTNLEAIGVELSAQEMKAI 262
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 80.6 bits (190), Expect = 3e-14
Identities = 50/154 (32%), Positives = 76/154 (49%), Gaps = 3/154 (1%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
V +T K M E K G + IG+SNF +D + QVE + +L Q+ ++
Sbjct: 112 VPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVL 171
Query: 188 DYCKRNGIVVMAFSPF--GPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLI-QKG 358
C+ G+ + A+SP G +F DD + IA+ H S QIVLR+LI Q
Sbjct: 172 TACRAAGMAMTAYSPIAQGKVF---------DDEVITEIAKAHNVSPAQIVLRWLIDQDS 222
Query: 359 VVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGT 460
V+ IP+S I+ N ++ D LS E+ +I +
Sbjct: 223 VIAIPRSSSDKHIKSNFEIADLKLSQEETGRINS 256
>UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1;
Bacillus coagulans 36D1|Rep: Plant-metabolite
dehydrogenase - Bacillus coagulans 36D1
Length = 113
Score = 80.6 bits (190), Expect = 3e-14
Identities = 40/97 (41%), Positives = 65/97 (67%)
Frame = +2
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
++ K++ I+ A+ P G ++ L + P LV + +K+GK+ QIVLR+ +++G+V
Sbjct: 3 EFLKQHNILHDAWGPLGQGKNNLL-----EQPVLVELGKKYGKTPAQIVLRWHVERGIVV 57
Query: 368 IPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
IPKSV +RI+EN ++FDF+L+ EDM KI + N KR
Sbjct: 58 IPKSVTPSRIKENSEIFDFSLTPEDMEKIASLNTGKR 94
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 80.6 bits (190), Expect = 3e-14
Identities = 41/136 (30%), Positives = 76/136 (55%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
+DY+ T++ ME+ G ++IG+SNFN +++ +L + P+V Q+E + +L Q L+
Sbjct: 134 IDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLL 193
Query: 188 DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVP 367
+C+ GI++ A+SP G ++ DDP + +A + ++ + +Q+G V
Sbjct: 194 QFCQSKGILIEAYSPLGNNQTGEPRTV--DDPLVHRVAGELSLDPGPLLASWGVQRGTVV 251
Query: 368 IPKSVKKNRIEENIDV 415
+ KSV RI N+ V
Sbjct: 252 LSKSVTPARIAANLRV 267
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 80.6 bits (190), Expect = 3e-14
Identities = 44/167 (26%), Positives = 85/167 (50%), Gaps = 2/167 (1%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
+T M + G +++G+SNF+ Q+ + +V Q+E + QD+++++C+
Sbjct: 101 ETMNAMATLHDQGKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCR 160
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
VV A +P G + DD + ++EK+ +S QIVL++ ++ VV +PKS
Sbjct: 161 DTDTVVEAAAPLGRT------KVFADD-IIQDLSEKYDRSPAQIVLKWAVENNVVVLPKS 213
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT--VGMSFWQDHPY 514
+ +N D+FD+ L + D +I +E+ G++ W + Y
Sbjct: 214 SSPEHVRQNFDLFDWELDATDRERIDAIEREQAVYDTGINDWDNDTY 260
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 79.8 bits (188), Expect = 6e-14
Identities = 45/163 (27%), Positives = 87/163 (53%), Gaps = 6/163 (3%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
YL W +E + GL + +G SN ++D +L + +I P++ ++E++ Q +L +
Sbjct: 152 YLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARIPPALNEMELHPCFQQPELFAH 211
Query: 194 CKRNGIVVMAFSPFGPMF---HDSLPS--IRPDDPTLVAIAEKHGKSVTQIVLRYLIQKG 358
C R+GI + +SP G D P + +DP +V IA +HG + L++ + +G
Sbjct: 212 CVRHGIQPVGYSPLGSPSRPERDRTPGDVVDTEDPVVVRIAREHGVHPALVCLKWAVARG 271
Query: 359 VVPIPKSVKKNRIEENI-DVFDFNLSSEDMNKIGTFNKEKRTV 484
VPIP SVK + N+ V + L+++++ + ++ +R +
Sbjct: 272 QVPIPFSVKPAQYTANLRAVVEDPLTAQEVADLAAADRGERLI 314
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 79.8 bits (188), Expect = 6e-14
Identities = 39/156 (25%), Positives = 79/156 (50%), Gaps = 1/156 (0%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYC 196
+++W M E G +S+G+SNF ++ + ++ + P+V QVE + H QD L+ YC
Sbjct: 128 VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYC 187
Query: 197 KRNGIVVMAFSPFG-PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
N I A+S G P + L ++P + +A+K+ + ++L + +G+ +P
Sbjct: 188 NENNIHFQAYSSLGSPTYRKQL----SEEPLIKELAQKYNVEIPVLLLGFAYCQGISVLP 243
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRT 481
++ + N V ++ ED++++ E +T
Sbjct: 244 RTTNPEHVATNFKVTKLAITQEDIDRLLALTVEHKT 279
>UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 315
Score = 79.4 bits (187), Expect = 8e-14
Identities = 44/157 (28%), Positives = 91/157 (57%), Gaps = 4/157 (2%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
+++T+K ME+ +S+G+ + + +D +L+ +KP + Q+EV+ KL+ Y
Sbjct: 98 FVETYKKMEKLVG-PKCRSLGVCSLSQKSMDVLLKECTVKPVINQIEVHPFNPSLKLVPY 156
Query: 194 CKRNGIVVMAFSPFG----PMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGV 361
C GI V+++ P G ++ D+ S + TL ++A ++ S+ I++ +L+Q+G+
Sbjct: 157 CLDKGIQVISWGPLGGGPKSLYFDT--SSMYNHKTLTSLASRYNVSIELIMISWLVQRGI 214
Query: 362 VPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
VPIP S + R+++N+ +L+ E++ +I +KE
Sbjct: 215 VPIPHSASRARMDDNLS--PVSLTDEEVGQINDVHKE 249
>UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid
reductase - Picrophilus torridus
Length = 283
Score = 79.4 bits (187), Expect = 8e-14
Identities = 46/153 (30%), Positives = 81/153 (52%), Gaps = 4/153 (2%)
Frame = +2
Query: 8 VDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVL--QVEVN--LHLGQ 175
VD +T K ME + G+ + IG+SNFN ++ + + K ++ QVE N + +
Sbjct: 108 VDIKETMKAMEHLVDTGMIRYIGVSNFNVNELKSAM-SAMSKYEIVSNQVEYNPLVRYIE 166
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
++ ++C++N I ++A+SP M + I D+ IA K +V Q++L +++ K
Sbjct: 167 PEISEFCRKNSISIIAYSPL--MHGHDIDPISKDESPFNIIANKRNATVRQVILAWILSK 224
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKI 454
IPKS + EN+ + NLSSE+ + I
Sbjct: 225 NFFAIPKSNVPEHVIENVKSMNINLSSEETSMI 257
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 79.0 bits (186), Expect = 1e-13
Identities = 55/163 (33%), Positives = 81/163 (49%), Gaps = 3/163 (1%)
Frame = +2
Query: 5 IVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQID---RILENGQIKPSVLQVEVNLHLGQ 175
+ DYL + E + GLA+ IG+SNF ID R+L++ I + QVE ++++
Sbjct: 114 LADYLGQFA---EVFDSGLARQIGVSNFTKAMIDESIRLLDSRTITTN--QVECHVYMQN 168
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
+IDYC+ GI V A+SP DP L I + G + QI L +LI K
Sbjct: 169 RPIIDYCQNLGIAVTAYSPLA-------RGAVVGDPVLEEIGKARGATSDQIALAFLIAK 221
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTV 484
G V IP S K+ RI +N + L+ ++ +I K R V
Sbjct: 222 GHVVIPSSSKRGRIMQNFEARKITLTPAEIKRIEGLEKGMRLV 264
>UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces
cerevisiae Probable oxidoreductase YJR096W; n=2;
Yarrowia lipolytica|Rep: Similar to sp|P47137
Saccharomyces cerevisiae Probable oxidoreductase YJR096W
- Yarrowia lipolytica (Candida lipolytica)
Length = 287
Score = 79.0 bits (186), Expect = 1e-13
Identities = 42/147 (28%), Positives = 81/147 (55%), Gaps = 1/147 (0%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILE-NGQIKPSVLQVEVNLHLGQDKLIDY 193
+ WK + E + G +++ +SN+ + + + + KP + Q+E + + DY
Sbjct: 131 MKVWKALSEFVDDGKIRTLAVSNYGVKHLKEFWDADTKYKPVLNQIESSPWNVHQDIHDY 190
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C + IVV +SP + + D+P + ++A+K+ K+ QI++R+ I KG++PIP
Sbjct: 191 CNEHDIVVEQYSPL-------IRGKKFDEPGVQSLAKKYNKTPAQILIRWGIDKGMLPIP 243
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKI 454
KS + R + N DVFDF L+ +++ +
Sbjct: 244 KSDQPQRQKSNADVFDFKLTPDEVTAL 270
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 78.6 bits (185), Expect = 1e-13
Identities = 46/153 (30%), Positives = 83/153 (54%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y++++ + + + LG +S+ ++NF + I+ I P + QVE++ Q +
Sbjct: 129 YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAV 188
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ G+V A+SP G DSL + + IA+ + K+ Q+ LR++ Q G +P
Sbjct: 189 DRELGVVTEAWSPLGR--GDSLNA-----EAITLIAQCYEKTPAQVTLRWIHQLGCSVVP 241
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKE 472
KS R EN+D+FDF L++EDMN I + +++
Sbjct: 242 KSANPQRQRENLDIFDFELNTEDMNSITSLDEQ 274
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 78.6 bits (185), Expect = 1e-13
Identities = 45/159 (28%), Positives = 94/159 (59%), Gaps = 1/159 (0%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQ-IKPSVLQVEVNLHLGQDKLIDYCK 199
+W + + + G +SIG+SN+ + +L + + I P+V QVE + + Q +L++YC+
Sbjct: 173 SWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCR 232
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
++GI + A+S G + +R +D T+ ++A+ K+ Q++LR+ I++ V +PK+
Sbjct: 233 QHGIFLQAYSSLG---SSNTAELR-EDETVQSVAKSLQKTPVQVLLRWAIEQEVGILPKA 288
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSF 496
++ I+EN+ + +F + +E M ++ N + +VG F
Sbjct: 289 RSRDHIQENVGL-EFEIPAEQMKQL---NGLRDSVGHKF 323
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 78.6 bits (185), Expect = 1e-13
Identities = 46/154 (29%), Positives = 86/154 (55%), Gaps = 2/154 (1%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILE--NGQIKPSVLQVEVNLHLGQDKLIDYC 196
TW+ +E+ +SIG+SN+ + +L N QIKP++ QVE + Q L+++C
Sbjct: 150 TWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFC 209
Query: 197 KRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
K N I++ ++ G + L + + ++ A+K G++ +Q++LRY ++ IPK
Sbjct: 210 KNNKIILESY---GSLAGGRLLN----NESVKEFAKKVGRTPSQLLLRYCLEHNCPVIPK 262
Query: 377 SVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
+ +R+ EN + DF LS + +N + NK++R
Sbjct: 263 TENVHRLIENQMILDFTLSDDIVNSLDKLNKDQR 296
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/160 (30%), Positives = 75/160 (46%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCK 199
DTW +E+ G +SIG+SN+ I+ + I+P V Q+E + H + L YC
Sbjct: 130 DTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYHPHFQRKVLRAYCN 189
Query: 200 RNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKS 379
+N I+ AFSP G L D T+ IA H +V ++L ++++ + KS
Sbjct: 190 KNEILFQAFSPLGRGNKTLL-----GDSTMERIALCHKTTVANVILAWIMKGKYGVVAKS 244
Query: 380 VKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFW 499
V +R+ EN LS ++ KI N E V W
Sbjct: 245 VTPSRVAENYTSLSLELSDDEFEKINGLNLETPYVEDRGW 284
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/155 (29%), Positives = 76/155 (49%)
Frame = +2
Query: 14 YLDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDY 193
Y + WK ME+ ++IG+SNF +D +L + P+V QVE++ Q +L
Sbjct: 121 YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAK 180
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
C+ GI V A+SP G + +++ +A K+ + QIVL + + +G + IP
Sbjct: 181 CRELGIAVEAYSPLGQGADLNATAVKD-------LAGKYDATPAQIVLAWHLAQGTIVIP 233
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKR 478
KS R+ EN+ LS ++++I R
Sbjct: 234 KSADSKRMRENLGAVAVELSPAELSEISALESGAR 268
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 77.8 bits (183), Expect = 2e-13
Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 1/152 (0%)
Frame = +2
Query: 17 LDTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG-QIKPSVLQVEVNLHLGQDKLIDY 193
LD+W + E G +S+G+SNF I ++++ ++ P Q+E + Q ++
Sbjct: 133 LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAA 192
Query: 194 CKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIP 373
+ + I+V A+ P + DPTL +A + GK+ Q++LR+L+Q G+V +P
Sbjct: 193 SEAHSIIVQAYCPLARGHYYG-------DPTLKKVAAETGKTEAQVMLRWLVQHGIVALP 245
Query: 374 KSVKKNRIEENIDVFDFNLSSEDMNKIGTFNK 469
KS R EN + F LS E M ++ ++
Sbjct: 246 KSSNLQRQVENAECLTFVLSDEQMKELDALDR 277
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 77.0 bits (181), Expect = 4e-13
Identities = 48/154 (31%), Positives = 71/154 (46%), Gaps = 1/154 (0%)
Frame = +2
Query: 47 KNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIVVMAF 226
K G ++IG++NF + + +E+ Q + QVE ++ L Q KL+ Y K I ++A+
Sbjct: 124 KQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKLMAYMKSRSIPLVAY 183
Query: 227 SPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLI-QKGVVPIPKSVKKNRIEE 403
P D TL I KHG Q+ L++L+ Q GV IPK+ + +
Sbjct: 184 CPLA-------QGRAAGDETLAGIGRKHGAGAAQVALKWLLDQDGVAAIPKAARPESQQA 236
Query: 404 NIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQD 505
N D L ED I K+KR V F D
Sbjct: 237 NWDAMKVQLDDEDRATIAALPKDKRFVNPGFAPD 270
>UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A
- Sulfolobus acidocaldarius
Length = 267
Score = 77.0 bits (181), Expect = 4e-13
Identities = 46/148 (31%), Positives = 84/148 (56%), Gaps = 3/148 (2%)
Frame = +2
Query: 20 DTWKGMEEAKNLGLAKSIGISNFNTTQIDRILENG---QIKPSVLQVEVNLHLGQDKLID 190
+T ME+ ++G+ + IG+SNF+ +D+ + + +I + +Q + + +I
Sbjct: 123 ETISAMEKLIDMGVVRCIGVSNFDVKLLDQAIHSTKKYEIVANQIQYSIYRLTPERDVIP 182
Query: 191 YCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPI 370
+ ++N + ++A+SP G S+ S + L IA K+GK+ Q+ L YL ++ + PI
Sbjct: 183 FAEKNKVTIIAYSPLG---QGSISS----ESRLKDIALKYGKTQAQVALAYLKRRSI-PI 234
Query: 371 PKSVKKNRIEENIDVFDFNLSSEDMNKI 454
PK+V+K I+E DV F+L ED N+I
Sbjct: 235 PKAVQKTHIDEIADVMKFDLRDEDYNEI 262
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 76.2 bits (179), Expect = 7e-13
Identities = 48/160 (30%), Positives = 79/160 (49%), Gaps = 1/160 (0%)
Frame = +2
Query: 29 KGMEEAKNLGLAKSIGISNFNTTQIDRILEN-GQIKPSVLQVEVNLHLGQDKLIDYCKRN 205
K ++ K GL + IG+SNF +Q+D L G+ Q+EV+ + +L+ YC+RN
Sbjct: 120 KELKACKERGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRN 179
Query: 206 GIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVK 385
I V A+ P G + + +D L IA H + + + L +L K +V IP S
Sbjct: 180 NIQVTAYMPLG------VGKVMEND-ILNDIASAHDTTPSAVALAWLSHKKIVAIPSSTN 232
Query: 386 KNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSFWQD 505
N + +N+ L++E++ KI ++R V F D
Sbjct: 233 VNHMRDNLTAKQMMLTAEEIEKIDGIEPQERIVDPDFAPD 272
>UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os05g0456200 protein -
Oryza sativa subsp. japonica (Rice)
Length = 229
Score = 76.2 bits (179), Expect = 7e-13
Identities = 43/127 (33%), Positives = 75/127 (59%), Gaps = 2/127 (1%)
Frame = +2
Query: 23 TWKGMEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKR 202
TW+ ME+ + G A++IG+SNF+ +++ +L ++ P+V QVE + Q KL C+
Sbjct: 80 TWQAMEKLYDSGKARAIGVSNFSCKKLEDLLNVARVPPAVNQVECHPVWQQGKLRKLCQS 139
Query: 203 NGIVVMAFSPFGPMFH--DSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPK 376
G+ + A++P G + P++ PT+++IA+K KS Q+ LR+ IQ G +PK
Sbjct: 140 KGVHLSAYAPLGSPGSPGNDGPNVL-SHPTVISIAKKLQKSPAQVALRWGIQMGQSVLPK 198
Query: 377 SVKKNRI 397
S + R+
Sbjct: 199 SDNEVRL 205
>UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Proteobacteria|Rep: Oxidoreductase,
aldo/keto reductase family - Methylococcus capsulatus
Length = 283
Score = 75.4 bits (177), Expect = 1e-12
Identities = 46/145 (31%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +2
Query: 11 DYLDTWKGMEEAKNLGLAKSIGISN-FNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLI 187
D LD W+ ME + G A+ +GISN + ++R+ ++KP+V+Q D+ I
Sbjct: 134 DTLDVWRAMETVFDGGGARQLGISNCYRPELLERLYRWSRVKPAVVQNRFYAETRYDREI 193
Query: 188 -DYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVV 364
++C++N IV +F + PSI T+ A+A HG++ QI RYL Q GVV
Sbjct: 194 REFCRQNRIVYQSFWTL-----TANPSILAH-ATVRALAATHGRTPAQIFFRYLTQIGVV 247
Query: 365 PIPKSVKKNRIEENIDVFDFNLSSE 439
P+ + + + E++ +F+F L+ +
Sbjct: 248 PLTGTASEAHMREDLAIFEFELTPD 272
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 74.1 bits (174), Expect = 3e-12
Identities = 45/140 (32%), Positives = 72/140 (51%)
Frame = +2
Query: 35 MEEAKNLGLAKSIGISNFNTTQIDRILENGQIKPSVLQVEVNLHLGQDKLIDYCKRNGIV 214
+ K+ G + IG+SN N Q+ + QVE++ +L Q L+ + + +
Sbjct: 120 LNAVKDAGKTRFIGVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHSLVAAARDSAVA 179
Query: 215 VMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQKGVVPIPKSVKKNR 394
V A+ +G M ++P DP L I ++GKS Q+ LR+L+Q+G V + K+ R
Sbjct: 180 VTAY--YG-MADGAVPK----DPVLQQIGARYGKSAAQVGLRWLVQQGYVALSKTANPAR 232
Query: 395 IEENIDVFDFNLSSEDMNKI 454
+ ENI +FDF L DM I
Sbjct: 233 VAENIAIFDFALDETDMAAI 252
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 74.1 bits (174), Expect = 3e-12
Identities = 49/167 (29%), Positives = 86/167 (51%), Gaps = 3/167 (1%)
Frame = +2
Query: 5 IVDYLDTWKGMEEAKNLGLAKSIGISNFNTTQIDR---ILENGQIKPSVLQVEVNLHLGQ 175
+V+YL K + + GL + IG+SNF Q+ + IL G I + QVEV+ +L
Sbjct: 121 MVEYLSELKAVLDK---GLTRRIGVSNFTNAQLAQAIAILGEGVIYTN--QVEVHPYLIN 175
Query: 176 DKLIDYCKRNGIVVMAFSPFGPMFHDSLPSIRPDDPTLVAIAEKHGKSVTQIVLRYLIQK 355
K+ D+C+++ ++V + PF + ++ D+ T+V +A H + QIVL +L Q
Sbjct: 176 RKVTDFCRQHNVLVTGYMPF------AYGAVLQDE-TIVNLASVHQATPAQIVLAWLRQL 228
Query: 356 GVVPIPKSVKKNRIEENIDVFDFNLSSEDMNKIGTFNKEKRTVGMSF 496
G IP S K++ + N+ NL+ ++ +I ++ R F
Sbjct: 229 GFATIPSSTKRDNVRSNLAAASINLTPAEIEQINQLDRNHRVANPDF 275
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 696,934,776
Number of Sequences: 1657284
Number of extensions: 13494172
Number of successful extensions: 38479
Number of sequences better than 10.0: 453
Number of HSP's better than 10.0 without gapping: 36848
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38103
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55785129165
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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