Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= an--0138
(768 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t... 93 1e-18
BC031251-1|AAH31251.1| 375|Homo sapiens EGF-like, fibronectin t... 93 1e-18
AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens ... 93 1e-18
AK092479-1|BAC03900.1| 463|Homo sapiens protein ( Homo sapiens ... 93 1e-18
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 92 2e-18
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 91 3e-18
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 91 3e-18
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 91 3e-18
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 91 3e-18
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 90 7e-18
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 90 7e-18
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 90 7e-18
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 90 7e-18
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 89 2e-17
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 3e-16
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 3e-16
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 85 3e-16
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 85 3e-16
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 85 3e-16
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 85 3e-16
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 85 3e-16
BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein. 83 8e-16
BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein. 75 2e-13
BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein. 75 2e-13
AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein pr... 75 2e-13
AB300051-1|BAF64841.1| 1044|Homo sapiens MEGF11 protein. 75 2e-13
AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA178... 75 2e-13
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 75 4e-13
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 75 4e-13
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 75 4e-13
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 75 4e-13
AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein. 73 1e-12
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 73 1e-12
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 73 1e-12
BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophil... 71 3e-12
AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein. 71 3e-12
AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein. 71 3e-12
AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein. 71 3e-12
AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein. 71 3e-12
AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2 pr... 71 3e-12
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 71 6e-12
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 71 6e-12
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 71 6e-12
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 71 6e-12
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 6e-12
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 6e-12
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 6e-12
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 71 6e-12
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 71 6e-12
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 71 6e-12
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 71 6e-12
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 70 1e-11
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 70 1e-11
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 69 1e-11
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 69 1e-11
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 69 1e-11
U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein. 69 2e-11
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 69 2e-11
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 69 2e-11
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 69 2e-11
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 69 2e-11
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 69 2e-11
BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein. 68 3e-11
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 67 6e-11
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 67 6e-11
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 65 3e-10
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 65 3e-10
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 65 3e-10
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 65 3e-10
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 65 3e-10
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 65 3e-10
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 65 3e-10
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 65 3e-10
U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein ... 64 4e-10
BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and di... 64 4e-10
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 64 5e-10
BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog (D... 64 7e-10
BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF re... 64 7e-10
AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein. 64 7e-10
AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multip... 64 7e-10
BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein. 63 1e-09
AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein. 63 1e-09
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 63 1e-09
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 63 1e-09
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 63 1e-09
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 63 1e-09
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 63 1e-09
AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein pr... 63 1e-09
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 63 1e-09
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 63 1e-09
AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF re... 63 1e-09
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 63 1e-09
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 63 1e-09
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 62 2e-09
BC063620-1|AAH63620.1| 488|Homo sapiens AGRN protein protein. 62 2e-09
BC007649-1|AAH07649.1| 488|Homo sapiens AGRN protein protein. 62 2e-09
AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein. 62 2e-09
AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multip... 62 2e-09
AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophil... 62 2e-09
AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein. 62 2e-09
AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein pr... 62 2e-09
AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein. 62 2e-09
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 62 2e-09
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 62 2e-09
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 62 3e-09
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 61 4e-09
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 61 4e-09
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 61 4e-09
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant... 61 4e-09
AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein. 61 5e-09
U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein ... 60 6e-09
BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein. 60 6e-09
U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged pr... 60 9e-09
U15981-1|AAA75365.1| 310|Homo sapiens dlk protein. 60 9e-09
AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar t... 60 9e-09
AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar t... 60 9e-09
AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein. 60 9e-09
AB018286-1|BAA34463.2| 1205|Homo sapiens KIAA0743 protein protein. 60 1e-08
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 59 1e-08
D86566-1|BAA13116.1| 955|Homo sapiens notch related protein pro... 59 2e-08
DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin... 58 3e-08
DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein. 58 3e-08
DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein. 58 3e-08
BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog (D... 58 3e-08
BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog (D... 58 3e-08
BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog (D... 58 3e-08
AJ316284-1|CAC87720.2| 1392|Homo sapiens neurexin 3-alpha protein. 58 3e-08
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 58 3e-08
Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein... 58 5e-08
U15979-1|AAA75364.1| 382|Homo sapiens dlk protein. 58 5e-08
DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein. 57 8e-08
BC033188-1|AAH33188.1| 152|Homo sapiens EGF-like, fibronectin t... 57 8e-08
BC033177-1|AAH33177.1| 152|Homo sapiens EGF-like, fibronectin t... 57 8e-08
AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multip... 57 8e-08
AK092994-1|BAC04013.1| 152|Homo sapiens protein ( Homo sapiens ... 57 8e-08
BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein. 56 1e-07
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 56 1e-07
AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precurs... 55 2e-07
AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precurso... 55 2e-07
AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 55 2e-07
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 55 2e-07
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 55 2e-07
AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 55 2e-07
AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1 (Droso... 55 2e-07
AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein. 55 2e-07
AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isofor... 55 2e-07
AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 55 3e-07
AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 55 3e-07
AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1 (Droso... 55 3e-07
AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1 (alt... 55 3e-07
AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein. 55 3e-07
BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophil... 54 4e-07
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor ... 54 4e-07
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 54 4e-07
AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2 p... 54 6e-07
AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 54 6e-07
AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 54 6e-07
AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2 (Droso... 54 6e-07
AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2 (Droso... 54 6e-07
AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein. 54 7e-07
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 53 1e-06
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 53 1e-06
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 53 1e-06
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 53 1e-06
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 53 1e-06
Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein. 53 1e-06
BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein. 53 1e-06
AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein. 53 1e-06
AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein. 53 1e-06
AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein. 53 1e-06
AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein. 53 1e-06
AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein. 53 1e-06
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ... 52 2e-06
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ... 52 2e-06
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote... 52 2e-06
J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroit... 52 2e-06
D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) pro... 52 2e-06
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr... 52 2e-06
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro... 52 2e-06
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 52 2e-06
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 52 2e-06
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 52 3e-06
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 52 3e-06
BC150275-1|AAI50276.1| 1642|Homo sapiens neurexin 2 protein. 52 3e-06
AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein. 52 3e-06
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 52 3e-06
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 52 3e-06
AB023138-1|BAA76765.2| 1658|Homo sapiens KIAA0921 protein protein. 52 3e-06
AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein. 51 5e-06
BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein pr... 50 9e-06
BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein. 50 9e-06
BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein. 50 9e-06
BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2 (Drosop... 50 9e-06
BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-termi... 50 9e-06
BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2 (Drosop... 50 9e-06
AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2 (Drosop... 50 9e-06
AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2 (Drosop... 50 9e-06
AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens ... 50 9e-06
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 50 1e-05
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 50 1e-05
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 50 1e-05
AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1 (Droso... 49 2e-05
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 49 2e-05
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 49 2e-05
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 49 2e-05
BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein. 49 2e-05
BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein. 49 2e-05
AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein. 49 2e-05
AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein. 49 2e-05
AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein. 49 2e-05
AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein. 49 2e-05
AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein. 49 2e-05
AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein. 49 2e-05
Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)... 48 3e-05
U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain pro... 48 3e-05
AL050329-2|CAB99359.1| 399|Homo sapiens protein ( Human DNA seq... 48 3e-05
AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens ... 48 3e-05
M59832-1|AAA63215.1| 1130|Homo sapiens merosin protein. 48 4e-05
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 48 4e-05
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 48 4e-05
BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1... 48 4e-05
AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein. 48 4e-05
AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (meros... 48 4e-05
AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (meros... 48 4e-05
AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (meros... 48 4e-05
AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (meros... 48 4e-05
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 48 4e-05
AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (meros... 48 4e-05
AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (meros... 48 4e-05
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 48 4e-05
AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1... 48 4e-05
AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein. 48 4e-05
AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS... 48 4e-05
AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein p... 48 4e-05
AB208922-1|BAD92159.1| 1853|Homo sapiens laminin alpha 2 subunit... 48 4e-05
AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain c... 47 6e-05
X73902-1|CAA52108.1| 1193|Homo sapiens nicein protein. 47 9e-05
U31201-1|AAC50457.1| 1193|Homo sapiens laminin gamma2 chain prot... 47 9e-05
U31200-1|AAC50456.1| 1111|Homo sapiens alternatively spliced lam... 47 9e-05
BC113378-1|AAI13379.1| 1111|Homo sapiens laminin, gamma 2 protein. 47 9e-05
BC112286-1|AAI12287.1| 1111|Homo sapiens laminin, gamma 2 protein. 47 9e-05
BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein. 47 9e-05
AL354953-2|CAH70980.1| 1193|Homo sapiens laminin, gamma 2 protein. 47 9e-05
AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro... 47 9e-05
AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant... 47 9e-05
AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. 47 9e-05
AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein. 47 9e-05
BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein pr... 46 1e-04
BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein pr... 46 1e-04
AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing p... 46 1e-04
AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand f... 46 1e-04
AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AK074051-1|BAB84877.1| 1736|Homo sapiens FLJ00122 protein protein. 46 1e-04
Z15009-1|CAA78729.1| 1111|Homo sapiens Laminin protein. 46 1e-04
Z15008-1|CAA78728.1| 1193|Homo sapiens Laminin protein. 46 1e-04
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 46 1e-04
BX640729-1|CAE45845.1| 674|Homo sapiens hypothetical protein pr... 46 1e-04
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 46 1e-04
AY481573-1|AAS47698.1| 5202|Homo sapiens Usher syndrome 2A isofo... 46 1e-04
AL513305-1|CAH73621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 1e-04
AL445650-4|CAH70621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 1e-04
AL358858-2|CAH71588.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 1e-04
AL358452-1|CAI19189.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 1e-04
AL139259-1|CAI23041.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 1e-04
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 46 1e-04
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 46 1e-04
AB086825-1|BAC45250.1| 788|Homo sapiens receptor protein tyrosi... 46 1e-04
AY311388-1|AAP74958.1| 2551|Homo sapiens FEX2 protein. 46 2e-04
AY227444-1|AAO39681.1| 1416|Homo sapiens hyaluronan receptor for... 46 2e-04
AK024503-1|BAB15793.1| 1192|Homo sapiens FLJ00112 protein protein. 46 2e-04
AJ295695-1|CAC82105.1| 2551|Homo sapiens stabilin-2 protein. 46 2e-04
AF160476-1|AAF82398.1| 897|Homo sapiens CD44-like precursor FEL... 46 2e-04
AB052958-1|BAC15608.1| 2551|Homo sapiens FELE-2 protein. 46 2e-04
BC133013-1|AAI33014.1| 594|Homo sapiens EGF-like-domain, multip... 45 3e-04
BC133011-1|AAI33012.1| 594|Homo sapiens EGF-like-domain, multip... 45 3e-04
AY358133-1|AAQ88500.1| 594|Homo sapiens TDKS9424 protein. 45 3e-04
AL589916-3|CAM13294.1| 594|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL589916-2|CAI12363.2| 619|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL365217-4|CAM23289.1| 594|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL365217-3|CAI16606.1| 619|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL132767-2|CAM28320.1| 594|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL132767-1|CAI22904.1| 619|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL109612-2|CAM27006.1| 594|Homo sapiens EGF-like-domain, multip... 45 3e-04
AL109612-1|CAI18881.1| 619|Homo sapiens EGF-like-domain, multip... 45 3e-04
AB011536-1|BAA32464.1| 1364|Homo sapiens MEGF2 protein. 45 3e-04
M35672-1|AAA51981.1| 291|Homo sapiens F9 protein. 45 3e-04
M11309-1|AAA52023.1| 461|Homo sapiens F9 protein. 45 3e-04
K02402-1|AAB59620.1| 461|Homo sapiens factor IX protein. 45 3e-04
K02053-1|AAA56822.1| 461|Homo sapiens protein ( Human factor IX... 45 3e-04
J00137-1|AAA52763.1| 461|Homo sapiens F9 protein. 45 3e-04
J00136-1|AAA98726.1| 462|Homo sapiens factor IX protein. 45 3e-04
DQ431790-1|ABF68979.1| 37|Homo sapiens coagulation factor IX p... 45 3e-04
BC109215-1|AAI09216.1| 461|Homo sapiens F9 protein protein. 45 3e-04
BC109214-1|AAI09215.1| 461|Homo sapiens F9 protein protein. 45 3e-04
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 45 3e-04
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 45 3e-04
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 45 3e-04
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 45 3e-04
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 45 3e-04
AL033403-1|CAI42103.1| 461|Homo sapiens coagulation factor IX (... 45 3e-04
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 45 3e-04
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 45 3e-04
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 45 3e-04
AF536327-1|AAM96188.1| 461|Homo sapiens coagulation factor IX (... 45 3e-04
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 45 3e-04
AL450324-2|CAI13283.1| 186|Homo sapiens protein ( Human DNA seq... 44 5e-04
S78220-1|AAB21215.1| 599|Homo sapiens prostaglandin endoperoxid... 44 6e-04
S36271-1|AAB22217.1| 599|Homo sapiens prostaglandin G/H synthas... 44 6e-04
S36219-1|AAB22216.1| 562|Homo sapiens prostaglandin G/H synthas... 44 6e-04
M59979-1|AAA03630.1| 599|Homo sapiens prostaglandin endoperoxid... 44 6e-04
M31822-1|AAA36439.1| 599|Homo sapiens prostaglandin-endoperoxid... 44 6e-04
DQ180742-1|ABA60099.1| 630|Homo sapiens cyclooxygenase 1b3 prot... 44 6e-04
DQ180741-1|ABA60098.1| 630|Homo sapiens cyclooxygenase 1b2 prot... 44 6e-04
BC105690-1|AAI05691.1| 195|Homo sapiens Unknown (protein for MG... 44 6e-04
BC078143-1|AAH78143.1| 446|Homo sapiens secretory protein LOC34... 44 6e-04
BC029840-1|AAH29840.1| 599|Homo sapiens prostaglandin-endoperox... 44 6e-04
BC013770-1|AAH13770.1| 530|Homo sapiens netrin G2 protein. 44 6e-04
AY449688-1|AAR08907.1| 599|Homo sapiens prostaglandin-endoperox... 44 6e-04
AL583807-2|CAH69984.3| 1575|Homo sapiens laminin, gamma 3 protein. 44 6e-04
AL583807-1|CAH69983.1| 1587|Homo sapiens laminin, gamma 3 protein. 44 6e-04
AL359636-8|CAM45741.1| 599|Homo sapiens prostaglandin-endoperox... 44 6e-04
AL359636-7|CAM45740.1| 562|Homo sapiens prostaglandin-endoperox... 44 6e-04
AL355872-3|CAI39529.1| 1587|Homo sapiens laminin, gamma 3 protein. 44 6e-04
AL355872-2|CAI39530.2| 1619|Homo sapiens laminin, gamma 3 protein. 44 6e-04
AL353631-2|CAI16125.1| 530|Homo sapiens netrin G2 protein. 44 6e-04
AL353631-1|CAI16126.1| 522|Homo sapiens netrin G2 protein. 44 6e-04
AL162424-14|CAI14715.1| 599|Homo sapiens prostaglandin-endopero... 44 6e-04
AL162424-13|CAI14714.1| 562|Homo sapiens prostaglandin-endopero... 44 6e-04
AL159997-4|CAI40856.1| 530|Homo sapiens netrin G2 protein. 44 6e-04
AL159997-3|CAI40855.1| 522|Homo sapiens netrin G2 protein. 44 6e-04
AF440204-1|AAL33601.1| 599|Homo sapiens prostaglandin-endoperox... 44 6e-04
AF131842-1|AAD20057.1| 260|Homo sapiens Unknown protein. 44 6e-04
AF041835-1|AAD36991.1| 1587|Homo sapiens laminin gamma 3 chain p... 44 6e-04
AC007748-1|AAY24263.1| 162|Homo sapiens unknown protein. 44 6e-04
AB208887-1|BAD92124.1| 1379|Homo sapiens laminin, gamma 3 precur... 44 6e-04
AB058760-1|BAB47486.2| 549|Homo sapiens KIAA1857 protein protein. 44 6e-04
EF539882-1|ABS86974.1| 1547|Homo sapiens NRXN1-alpha protein. 44 8e-04
BC150247-1|AAI50248.1| 1496|Homo sapiens NRXN1 protein protein. 44 8e-04
BC141808-1|AAI41809.1| 446|Homo sapiens MGC34761 protein protein. 44 8e-04
BC039068-1|AAH39068.1| 301|Homo sapiens MGC34761 protein protein. 44 8e-04
AY572973-1|AAT77226.1| 755|Homo sapiens colon cancer secreted p... 44 8e-04
AY572972-1|AAT77225.1| 755|Homo sapiens colon cancer secreted p... 44 8e-04
AY358373-1|AAQ88739.1| 455|Homo sapiens LHPE306 protein. 44 8e-04
AK127756-1|BAC87116.1| 725|Homo sapiens protein ( Homo sapiens ... 44 8e-04
AK122716-1|BAC85505.1| 725|Homo sapiens ember 3 (SULT1A3). pro... 44 8e-04
AK074773-1|BAC11199.1| 446|Homo sapiens protein ( Homo sapiens ... 44 8e-04
AJ536328-1|CAD60276.1| 755|Homo sapiens AMACO protein. 44 8e-04
AF521893-1|AAP80866.1| 446|Homo sapiens unnamed secretory prote... 44 8e-04
AC007462-1|AAF03536.1| 681|Homo sapiens unknown protein. 44 8e-04
AB035356-1|BAA87821.1| 1477|Homo sapiens neurexin I-alpha protei... 44 8e-04
AB011150-1|BAA25504.2| 1542|Homo sapiens KIAA0578 protein protein. 44 8e-04
AY046055-2|AAL04411.1| 2812|Homo sapiens zonadhesin splice varia... 43 0.001
AF332977-1|AAK01433.1| 2812|Homo sapiens zonadhesin variant 3 pr... 43 0.001
AJ295142-1|CAC82720.1| 652|Homo sapiens C1q receptor protein pr... 43 0.001
AF448856-1|AAP41924.1| 303|Homo sapiens hypothetical protein pr... 43 0.001
U94333-1|AAB53110.1| 652|Homo sapiens C1qR(p) protein. 42 0.002
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 42 0.002
U27109-1|AAC52065.1| 1228|Homo sapiens prepromultimerin protein. 42 0.002
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 42 0.002
BC063848-1|AAH63848.1| 1228|Homo sapiens multimerin 1 protein. 42 0.002
BC028075-1|AAH28075.1| 652|Homo sapiens CD93 molecule protein. 42 0.002
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 42 0.002
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 42 0.002
AL118508-1|CAC00597.1| 652|Homo sapiens complement component 1,... 42 0.002
AF428259-1|AAP97299.1| 303|Homo sapiens hypothetical protein pr... 42 0.002
AC093759-2|AAY40957.1| 1228|Homo sapiens unknown protein. 42 0.002
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 42 0.002
AB209895-1|BAD93132.1| 671|Homo sapiens complement component 1,... 42 0.002
DQ431791-1|ABF68980.1| 37|Homo sapiens coagulation factor IX p... 42 0.002
AL355357-1|CAI16435.1| 95|Homo sapiens protein ( Human DNA seq... 42 0.002
AC044790-1|AAK68154.1| 1712|Homo sapiens NRXN2 protein. 42 0.002
AB177862-1|BAD66840.1| 1434|Homo sapiens KIAA0921 splice variant... 42 0.002
AB035266-1|BAA94075.1| 1712|Homo sapiens neurexin II protein. 42 0.002
D50030-1|BAA74450.1| 655|Homo sapiens hepatocyte growth factor ... 42 0.003
D14012-1|BAA03113.1| 655|Homo sapiens HGF activator precursor p... 42 0.003
BC112192-1|AAI12193.1| 655|Homo sapiens HGF activator, prepropr... 42 0.003
BC112190-1|AAI12191.1| 655|Homo sapiens HGF activator, prepropr... 42 0.003
BC068469-1|AAH68469.1| 432|Homo sapiens neurexin 3 protein. 42 0.003
BC062318-1|AAH62318.1| 559|Homo sapiens LAMA1 protein protein. 42 0.003
BC059368-1|AAH59368.1| 432|Homo sapiens neurexin 3 protein. 42 0.003
BC039051-1|AAH39051.1| 747|Homo sapiens LAMA1 protein protein. 42 0.003
AL590235-6|CAM21456.1| 655|Homo sapiens HGF activator protein. 42 0.003
AK126775-1|BAC86684.1| 952|Homo sapiens protein ( Homo sapiens ... 42 0.003
AC093384-1|AAY14680.1| 92|Homo sapiens unknown protein. 42 0.003
S83182-1|AAB46909.1| 560|Homo sapiens hyaluronan-binding protei... 41 0.004
EF025894-1|ABJ98522.1| 2721|Homo sapiens zonadhesin isoform 6 pr... 41 0.004
D49742-1|BAA08576.1| 560|Homo sapiens HGF activator like protei... 41 0.004
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 41 0.004
BC031412-1|AAH31412.1| 560|Homo sapiens hyaluronan binding prot... 41 0.004
AY534754-1|AAS16352.1| 560|Homo sapiens hyaluronan binding prot... 41 0.004
AY046055-1|AAL04413.1| 2721|Homo sapiens zonadhesin splice varia... 41 0.004
AL390197-1|CAH71108.1| 560|Homo sapiens hyaluronan binding prot... 41 0.004
AF332980-1|AAK01436.1| 2721|Homo sapiens zonadhesin variant 6 pr... 41 0.004
AF193046-1|AAG22474.1| 277|Homo sapiens unknown protein. 41 0.004
AY764262-1|AAW47409.1| 108|Homo sapiens netrin G1 isoform G1d p... 41 0.006
AL590427-6|CAH73385.1| 480|Homo sapiens netrin G1 protein. 41 0.006
AL513187-6|CAH73829.1| 480|Homo sapiens netrin G1 protein. 41 0.006
AK125557-1|BAC86201.1| 531|Homo sapiens protein ( Homo sapiens ... 41 0.006
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 41 0.006
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 40 0.007
BC045172-1|AAH45172.2| 749|Homo sapiens LAMB4 protein protein. 40 0.007
AL138836-3|CAC22313.2| 602|Homo sapiens multiple EGF-like-domai... 40 0.007
AF028816-1|AAC95123.1| 1761|Homo sapiens laminin beta-4 chain pr... 40 0.007
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 40 0.007
X13097-1|CAA31489.1| 291|Homo sapiens plasminogen activator pre... 40 0.010
X07393-1|CAA30302.1| 562|Homo sapiens protein ( Human fetal lun... 40 0.010
M18182-1|AAA36800.1| 562|Homo sapiens protein ( Human plasminog... 40 0.010
M15518-1|AAA60111.1| 562|Homo sapiens tissue-type plasminogen a... 40 0.010
K03021-1|AAA98809.1| 562|Homo sapiens plasminogen activator pro... 40 0.010
D01096-1|BAA00881.1| 532|Homo sapiens tissue plasminogen activa... 40 0.010
BT007060-1|AAP35709.1| 562|Homo sapiens plasminogen activator, ... 40 0.010
BC095403-1|AAH95403.1| 562|Homo sapiens plasminogen activator, ... 40 0.010
BC089434-1|AAH89434.1| 737|Homo sapiens regeneration associated... 40 0.010
BC018636-1|AAH18636.3| 562|Homo sapiens plasminogen activator, ... 40 0.010
BC013968-1|AAH13968.3| 562|Homo sapiens plasminogen activator, ... 40 0.010
BC007231-1|AAH07231.1| 562|Homo sapiens plasminogen activator, ... 40 0.010
AY291060-1|AAP34246.1| 291|Homo sapiens plasminogen activator, ... 40 0.010
AY221101-1|AAO34406.1| 562|Homo sapiens tissue plasminogen acti... 40 0.010
AK024477-1|BAB15767.1| 1382|Homo sapiens FLJ00070 protein protein. 40 0.010
AF135960-1|AAF62352.3| 1256|Homo sapiens latent transforming gro... 40 0.010
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 40 0.013
AY781194-1|AAW47415.1| 111|Homo sapiens netrin G1 isoform G1b p... 40 0.013
AY764267-1|AAW47414.1| 153|Homo sapiens netrin G1 isoform G1o p... 40 0.013
AY764266-1|AAW47413.1| 133|Homo sapiens netrin G1 isoform G1n p... 40 0.013
AY764265-1|AAW47412.1| 209|Homo sapiens netrin G1 isoform G1m p... 40 0.013
AY764264-1|AAW47411.1| 57|Homo sapiens netrin G1 isoform G1l p... 40 0.013
AY764260-1|AAW47407.1| 167|Homo sapiens netrin G1 isoform G1a p... 40 0.013
AL590427-3|CAH73381.1| 539|Homo sapiens netrin G1 protein. 40 0.013
AL513187-3|CAH73830.1| 539|Homo sapiens netrin G1 protein. 40 0.013
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 40 0.013
AK057327-1|BAB71429.1| 721|Homo sapiens protein ( Homo sapiens ... 40 0.013
AF463518-1|AAL68839.1| 1311|Homo sapiens cell recognition protei... 40 0.013
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 40 0.013
AC009396-1|AAF21147.1| 351|Homo sapiens neurexin III protein. 40 0.013
AB100094-1|BAC55272.1| 1308|Homo sapiens hypothetical protein pr... 40 0.013
AB051550-1|BAB21854.2| 1322|Homo sapiens KIAA1763 protein protein. 40 0.013
X58531-1|CAA41418.1| 2628|Homo sapiens laminin A chain protein. 39 0.017
BC034009-1|AAH34009.1| 181|Homo sapiens AGRN protein protein. 39 0.017
BC000059-1|AAH00059.2| 771|Homo sapiens CELSR1 protein protein. 39 0.017
AL354836-5|CAC22310.1| 3690|Homo sapiens laminin, alpha 5 protein. 39 0.017
AF522196-1|AAN45861.1| 870|Homo sapiens scavenger receptor type... 39 0.017
AF443072-1|AAM12527.1| 3695|Homo sapiens laminin alpha5 chain pr... 39 0.017
AB024433-1|BAD93345.1| 866|Homo sapiens NSR1 protein. 39 0.017
AB011105-1|BAA25459.1| 1645|Homo sapiens KIAA0533 protein protein. 39 0.017
BC030220-1|AAH30220.1| 438|Homo sapiens netrin G1 protein. 39 0.023
AY764263-1|AAW47410.1| 88|Homo sapiens netrin G1 isoform G1e p... 39 0.023
AY764261-1|AAW47408.1| 66|Homo sapiens netrin G1 isoform G1c p... 39 0.023
AY358365-1|AAQ88731.1| 438|Homo sapiens YLSR571 protein. 39 0.023
AL590427-5|CAH73382.1| 494|Homo sapiens netrin G1 protein. 39 0.023
AL590427-4|CAH73383.1| 438|Homo sapiens netrin G1 protein. 39 0.023
AL590427-2|CAH73384.1| 460|Homo sapiens netrin G1 protein. 39 0.023
AL513187-5|CAH73831.1| 494|Homo sapiens netrin G1 protein. 39 0.023
AL513187-4|CAH73832.1| 438|Homo sapiens netrin G1 protein. 39 0.023
AL513187-2|CAH73833.1| 460|Homo sapiens netrin G1 protein. 39 0.023
AK027841-1|BAB55404.1| 737|Homo sapiens protein ( Homo sapiens ... 39 0.023
X79683-1|CAA56130.1| 1798|Homo sapiens beta2/S laminin chain pro... 38 0.030
U57523-1|AAB06946.1| 446|Homo sapiens protein ( Human nel homol... 38 0.030
D89629-1|BAB46925.1| 815|Homo sapiens cerebral protein-12 protein. 38 0.030
D83018-1|BAA11681.1| 816|Homo sapiens nel-related protein 2 pro... 38 0.030
BC020544-1|AAH20544.1| 816|Homo sapiens NELL2 protein protein. 38 0.030
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 38 0.030
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 38 0.030
M59303-1|AAA36499.1| 320|Homo sapiens protein Z protein. 38 0.040
M55671-1|AAA36501.1| 422|Homo sapiens protein Z protein. 38 0.040
M55670-1|AAA36500.1| 400|Homo sapiens protein Z protein. 38 0.040
M13232-2|AAA88041.1| 444|Homo sapiens protein ( Human factor VI... 38 0.040
M13232-1|AAA88040.1| 466|Homo sapiens coagulation factor VII pr... 38 0.040
J02933-1|AAA51983.1| 466|Homo sapiens protein ( Human blood coa... 38 0.040
D83017-1|BAA11680.1| 810|Homo sapiens nel-related protein protein. 38 0.040
DQ142911-1|ABD17891.1| 466|Homo sapiens cogulation factor VII p... 38 0.040
BC130468-1|AAI30469.1| 444|Homo sapiens coagulation factor VII ... 38 0.040
BC096103-1|AAH96103.1| 763|Homo sapiens NELL1 protein protein. 38 0.040
BC096102-1|AAH96102.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 38 0.040
BC096101-1|AAH96101.1| 810|Homo sapiens NEL-like 1 (chicken) pr... 38 0.040
BC096100-1|AAH96100.1| 763|Homo sapiens NELL1 protein protein. 38 0.040
BC074907-1|AAH74907.1| 400|Homo sapiens protein Z, vitamin K-de... 38 0.040
BC074906-1|AAH74906.1| 400|Homo sapiens protein Z, vitamin K-de... 38 0.040
BC069674-1|AAH69674.1| 810|Homo sapiens nel-like 1, precursor p... 38 0.040
AY212252-1|AAP33841.1| 466|Homo sapiens FVII coagulation protei... 38 0.040
AL137002-16|CAI41388.1| 400|Homo sapiens protein Z, vitamin K-d... 38 0.040
AL137002-15|CAI41389.1| 422|Homo sapiens protein Z, vitamin K-d... 38 0.040
AL137002-10|CAI41381.1| 466|Homo sapiens coagulation factor VII... 38 0.040
AL137002-9|CAI41382.1| 444|Homo sapiens coagulation factor VII ... 38 0.040
AF466933-1|AAL66184.1| 466|Homo sapiens coagulation factor VII ... 38 0.040
AF440358-1|AAL27631.1| 400|Homo sapiens protein Z, vitamin K-de... 38 0.040
AF272774-1|AAK58686.2| 679|Homo sapiens factor VII active site ... 38 0.040
AB052951-1|BAC53753.1| 866|Homo sapiens SRECRP-1 protein. 38 0.040
AB033749-2|BAA85764.1| 422|Homo sapiens protein Z spliced varia... 38 0.040
AB033749-1|BAA85763.1| 400|Homo sapiens protein Z protein. 38 0.040
Z95636-1|CAB09137.1| 953|Homo sapiens laminin alpha 5 chain pro... 38 0.052
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 38 0.052
U04636-1|AAA57317.1| 604|Homo sapiens cyclooxygenase-2 protein. 38 0.052
M90100-1|AAA58433.1| 604|Homo sapiens cyclooxygenase-2 protein. 38 0.052
L15326-1|AAA35803.1| 604|Homo sapiens endoperoxide synthase typ... 38 0.052
L00153-1|AAB59510.1| 562|Homo sapiens plasminogen activator pro... 38 0.052
D28235-1|BAA05698.1| 604|Homo sapiens prostaglandin endoperoxid... 38 0.052
BC013734-1|AAH13734.1| 604|Homo sapiens prostaglandin-endoperox... 38 0.052
AY462100-1|AAR23927.1| 604|Homo sapiens cyclooxygenase 2 protein. 38 0.052
>BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 1009
Score = 92.7 bits (220), Expect = 1e-18
Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYV--EL 339
+PC PC +GG+C+P + + CDCPLG+ G CQ + E + F G Y+ +
Sbjct: 786 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDN 842
Query: 340 PASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDL 519
P L R SN V T DG+L ++ + PN D+ L + G +V ++L
Sbjct: 843 PDILKRVSGSRSN--VFMRFKTTAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNL 899
Query: 520 GGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYI 696
G G++SI+V+ NDG H+V A + + ++VD ++ + G+ +N + +Y+
Sbjct: 900 GSGVASIMVNGSFNDGRWHRVKA-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYV 958
Query: 697 GG---IPSWLNIHGYPGFIGCIEN 759
GG I N G +GCI +
Sbjct: 959 GGMKEIALHTNRQYMRGLVGCISH 982
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/203 (28%), Positives = 85/203 (41%), Gaps = 6/203 (2%)
Frame = +1
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASL 351
PC C C D +W C C LG G SC + + Q F G+ YV
Sbjct: 346 PCDETLCSADSFCVNDY-TWGGSRCQCTLGKGGESCSEDIVI-QYPQFFGHSYVTFEPLK 403
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
Y A A DG+L Y E + GD+ L I R + ++ G G+
Sbjct: 404 NSYQAFQITLEFRAEA----EDGLLLYCGENEH--GRGDFMSLAIIRRSLQFRFNCGTGV 457
Query: 532 SSIVVDVPINDGERHQVAARLHEDG-HAWLSV-DGVDKSAPATGISNVMNADSNIYIGGI 705
+ IV + I G H V L+ DG + L + +G + + G + + + +Y+GG
Sbjct: 458 AIIVSETKIKLGGWHMV--MLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGA 515
Query: 706 PS--WL-NIHG-YPGFIGCIENV 762
PS WL G GF GC++++
Sbjct: 516 PSAYWLVRATGTNRGFQGCVQSL 538
Score = 48.4 bits (110), Expect = 3e-05
Identities = 42/192 (21%), Positives = 79/192 (41%), Gaps = 2/192 (1%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG-QSVGFNGNGYVELPASL 351
C C +GGTC + ++ C CPLG+ G C+ L + Y P L
Sbjct: 569 CDEASCIHGGTCTAIKAD--SYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPL 626
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
L+ I + DGVL Y + D+ + + G V +D G G
Sbjct: 627 EPQHYLSFMEFEITFR-PDSGDGVLLYSYD----TGSKDFLSINLAGGHVEFRFDCGSGT 681
Query: 532 SSIVVDVPINDGERHQV-AARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
+ + P+ G H++ +R ++G + + + G + + +++I+IGG+P
Sbjct: 682 GVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQI-KCNTDIFIGGVP 740
Query: 709 SWLNIHGYPGFI 744
++ ++ G +
Sbjct: 741 NYDDVKKNSGVL 752
Score = 32.7 bits (71), Expect = 1.5
Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Frame = +1
Query: 37 ESCQCENGGSCST---ESTNCICPPGYTGSYCE 126
+ C +GG+C+ +S C+CP G+ G +CE
Sbjct: 570 DEASCIHGGTCTAIKADSYICLCPLGFKGRHCE 602
Score = 32.7 bits (71), Expect = 1.5
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSP 156
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 793 CAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 830
>BC031251-1|AAH31251.1| 375|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 375
Score = 92.7 bits (220), Expect = 1e-18
Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYV--EL 339
+PC PC +GG+C+P + + CDCPLG+ G CQ + E + F G Y+ +
Sbjct: 152 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDN 208
Query: 340 PASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDL 519
P L R SN V T DG+L ++ + PN D+ L + G +V ++L
Sbjct: 209 PDILKRVSGSRSN--VFMRFKTTAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNL 265
Query: 520 GGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYI 696
G G++SI+V+ NDG H+V A + + ++VD ++ + G+ +N + +Y+
Sbjct: 266 GSGVASIMVNGSFNDGRWHRVKA-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYV 324
Query: 697 GG---IPSWLNIHGYPGFIGCIEN 759
GG I N G +GCI +
Sbjct: 325 GGMKEIALHTNRQYMRGLVGCISH 348
Score = 35.5 bits (78), Expect = 0.21
Identities = 23/113 (20%), Positives = 52/113 (46%), Gaps = 1/113 (0%)
Frame = +1
Query: 409 TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQV-A 585
+ DGVL Y + D+ + + G V +D G G + + P+ G H++
Sbjct: 11 SGDGVLLYSYD----TGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRV 66
Query: 586 ARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSWLNIHGYPGFI 744
+R ++G + + + G + + +++I+IGG+P++ ++ G +
Sbjct: 67 SRTAKNGILQVDKQKIVEGMAEGGFTQI-KCNTDIFIGGVPNYDDVKKNSGVL 118
Score = 32.7 bits (71), Expect = 1.5
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSP 156
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 159 CAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 196
>AK097549-1|BAC05096.1| 775|Homo sapiens protein ( Homo sapiens cDNA
FLJ40230 fis, clone TESTI2022960, weakly similar to
Drosophila melanogaster SP2353 mRNA. ).
Length = 775
Score = 92.7 bits (220), Expect = 1e-18
Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYV--EL 339
+PC PC +GG+C+P + + CDCPLG+ G CQ + E + F G Y+ +
Sbjct: 552 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDN 608
Query: 340 PASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDL 519
P L R SN V T DG+L ++ + PN D+ L + G +V ++L
Sbjct: 609 PDILKRVSGSRSN--VFMRFKTTAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNL 665
Query: 520 GGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYI 696
G G++SI+V+ NDG H+V A + + ++VD ++ + G+ +N + +Y+
Sbjct: 666 GSGVASIMVNGSFNDGRWHRVKA-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYV 724
Query: 697 GG---IPSWLNIHGYPGFIGCIEN 759
GG I N G +GCI +
Sbjct: 725 GGMKEIALHTNRQYMRGLVGCISH 748
Score = 54.4 bits (125), Expect = 4e-07
Identities = 57/203 (28%), Positives = 85/203 (41%), Gaps = 6/203 (2%)
Frame = +1
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASL 351
PC C C D +W C C LG G SC + + Q F G+ YV
Sbjct: 112 PCDETLCSADSFCVNDY-TWGGSRCQCTLGKGGESCSEDIVI-QYPQFFGHSYVTFEPLK 169
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
Y A A DG+L Y G+ GD+ L I R + ++ G G+
Sbjct: 170 NSYQAFQITLEFRAEA----EDGLLLYC--GENEHGRGDFMSLAIIRRSLQFRFNCGTGV 223
Query: 532 SSIVVDVPINDGERHQVAARLHEDG-HAWLSV-DGVDKSAPATGISNVMNADSNIYIGGI 705
+ IV + I G H V L+ DG + L + +G + + G + + + +Y+GG
Sbjct: 224 AIIVSETKIKLGGWHTV--MLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGA 281
Query: 706 PS--WL-NIHG-YPGFIGCIENV 762
PS WL G GF GC++++
Sbjct: 282 PSAYWLVRATGTNRGFQGCVQSL 304
Score = 48.4 bits (110), Expect = 3e-05
Identities = 42/192 (21%), Positives = 79/192 (41%), Gaps = 2/192 (1%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG-QSVGFNGNGYVELPASL 351
C C +GGTC + ++ C CPLG+ G C+ L + Y P L
Sbjct: 335 CDEASCIHGGTCTAIKAD--SYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPL 392
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
L+ I + DGVL Y + D+ + + G V +D G G
Sbjct: 393 EPQHYLSFMEFEITFR-PDSGDGVLLYSYD----TGSKDFLSINLAGGHVEFRFDCGSGT 447
Query: 532 SSIVVDVPINDGERHQV-AARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
+ + P+ G H++ +R ++G + + + G + + +++I+IGG+P
Sbjct: 448 GVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQI-KCNTDIFIGGVP 506
Query: 709 SWLNIHGYPGFI 744
++ ++ G +
Sbjct: 507 NYDDVKKNSGVL 518
Score = 32.7 bits (71), Expect = 1.5
Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Frame = +1
Query: 37 ESCQCENGGSCST---ESTNCICPPGYTGSYCE 126
+ C +GG+C+ +S C+CP G+ G +CE
Sbjct: 336 DEASCIHGGTCTAIKADSYICLCPLGFKGRHCE 368
Score = 32.7 bits (71), Expect = 1.5
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSP 156
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 559 CAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 596
>AK092479-1|BAC03900.1| 463|Homo sapiens protein ( Homo sapiens
cDNA FLJ35160 fis, clone PLACE6011334, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 463
Score = 92.7 bits (220), Expect = 1e-18
Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYV--EL 339
+PC PC +GG+C+P + + CDCPLG+ G CQ + E + F G Y+ +
Sbjct: 240 HPCVRAPCAHGGSCRPRKEGY---DCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDN 296
Query: 340 PASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDL 519
P L R SN V T DG+L ++ + PN D+ L + G +V ++L
Sbjct: 297 PDILKRVSGSRSN--VFMRFKTTAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNL 353
Query: 520 GGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYI 696
G G++SI+V+ NDG H+V A + + ++VD ++ + G+ +N + +Y+
Sbjct: 354 GSGVASIMVNGSFNDGRWHRVKA-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYV 412
Query: 697 GG---IPSWLNIHGYPGFIGCIEN 759
GG I N G +GCI +
Sbjct: 413 GGMKEIALHTNRQYMRGLVGCISH 436
Score = 48.4 bits (110), Expect = 3e-05
Identities = 42/192 (21%), Positives = 79/192 (41%), Gaps = 2/192 (1%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG-QSVGFNGNGYVELPASL 351
C C +GGTC + ++ C CPLG+ G C+ L + Y P L
Sbjct: 23 CDEASCIHGGTCTAIKAD--SYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPL 80
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
L+ I + DGVL Y + D+ + + G V +D G G
Sbjct: 81 EPQHYLSFMEFEITFR-PDSGDGVLLYSYD----TGSKDFLSINLAGGHVEFRFDCGSGT 135
Query: 532 SSIVVDVPINDGERHQV-AARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
+ + P+ G H++ +R ++G + + + G + + +++I+IGG+P
Sbjct: 136 GVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQI-KCNTDIFIGGVP 194
Query: 709 SWLNIHGYPGFI 744
++ ++ G +
Sbjct: 195 NYDDVKKNSGVL 206
Score = 32.7 bits (71), Expect = 1.5
Identities = 12/33 (36%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Frame = +1
Query: 37 ESCQCENGGSCST---ESTNCICPPGYTGSYCE 126
+ C +GG+C+ +S C+CP G+ G +CE
Sbjct: 24 DEASCIHGGTCTAIKADSYICLCPLGFKGRHCE 56
Score = 32.7 bits (71), Expect = 1.5
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSP 156
C +GGSC E +C CP G+ G +C+ I + P
Sbjct: 247 CAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIP 284
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 92.3 bits (219), Expect = 2e-18
Identities = 80/269 (29%), Positives = 116/269 (43%), Gaps = 22/269 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-P 189
D E C++G +C C+C G+ G CE NPC L P
Sbjct: 2044 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------ENPCQLREP 2092
Query: 190 CRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQMPLE-------LGQ-SVGFNGNGYV 333
C +GGTC+ R + C G+ A LE GQ F+ +G++
Sbjct: 2093 CLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFL 2152
Query: 334 ELPASLLRYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEG-DYFLLRIERGFVVL 507
P + L P I L V T T G+L +Q +G D+ L ++ G +V
Sbjct: 2153 AFPGHVFSRS-LPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVF 2211
Query: 508 EWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADS 684
+ LG G + +V + PINDGE H+V A L E + VDG + S + G + +NA
Sbjct: 2212 RYQLGSGEARLVSEDPINDGEWHRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKG 2270
Query: 685 NIYIGGIPSWLNIHG---YPGFIGCIENV 762
N+YIGG P + G G GC++N+
Sbjct: 2271 NVYIGGAPDVATLTGGRFSSGITGCVKNL 2299
Score = 83.4 bits (197), Expect = 8e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 1793 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 1841
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 1842 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 1901
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 1902 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHR 1955
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 1956 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 1997
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 1788 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 1821
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila)
protein.
Length = 1529
Score = 91.5 bits (217), Expect = 3e-18
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 18/265 (6%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 183
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1076 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1127
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF-NGNGYVELPASLLRY 360
C+NG C N C C GY G C+ + SV F N Y+++P++ +R
Sbjct: 1128 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCEKLV----SVNFINKESYLQIPSAKVRP 1180
Query: 361 DELASNPAVIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
+N I L + T D G+L Y+ + D+ + + RG V +D G +S
Sbjct: 1181 Q---TN---ITLQIATDEDSGILLYK-------GDKDHIAVELYRGRVRASYDTGSHPAS 1227
Query: 538 IVVDV-PINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGGIPS 711
+ V INDG H + L D LSVDG + K + +N DS +Y+GG+P
Sbjct: 1228 AIYSVETINDGNFH-IVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPG 1286
Query: 712 WLNIHGY---PG-----FIGCIENV 762
N+ PG F GCI N+
Sbjct: 1287 KSNVASLRQAPGQNGTSFHGCIRNL 1311
Score = 50.8 bits (116), Expect = 5e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 975
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
C C G+ G +C++ ++
Sbjct: 976 EGEEDGFWCICADGFEGENCEVNVD 1000
Score = 46.8 bits (106), Expect = 9e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 958
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 998 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1048
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C + CDC GY G C + +
Sbjct: 1049 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1078
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 91.5 bits (217), Expect = 3e-18
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 18/265 (6%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 183
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1072 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1123
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF-NGNGYVELPASLLRY 360
C+NG C N C C GY G C+ + SV F N Y+++P++ +R
Sbjct: 1124 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCEKLV----SVNFINKESYLQIPSAKVRP 1176
Query: 361 DELASNPAVIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
+N I L + T D G+L Y+ + D+ + + RG V +D G +S
Sbjct: 1177 Q---TN---ITLQIATDEDSGILLYK-------GDKDHIAVELYRGRVRASYDTGSHPAS 1223
Query: 538 IVVDV-PINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGGIPS 711
+ V INDG H + L D LSVDG + K + +N DS +Y+GG+P
Sbjct: 1224 AIYSVETINDGNFH-IVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPG 1282
Query: 712 WLNIHGY---PG-----FIGCIENV 762
N+ PG F GCI N+
Sbjct: 1283 KSNVASLRQAPGQNGTSFHGCIRNL 1307
Score = 50.8 bits (116), Expect = 5e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 923 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 971
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
C C G+ G +C++ ++
Sbjct: 972 EGEEDGFWCICADGFEGENCEVNVD 996
Score = 46.8 bits (106), Expect = 9e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 916 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 954
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 994 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1044
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C + CDC GY G C + +
Sbjct: 1045 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1074
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 91.5 bits (217), Expect = 3e-18
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 18/265 (6%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 183
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1068 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1119
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF-NGNGYVELPASLLRY 360
C+NG C N C C GY G C+ + SV F N Y+++P++ +R
Sbjct: 1120 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCEKLV----SVNFINKESYLQIPSAKVRP 1172
Query: 361 DELASNPAVIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
+N I L + T D G+L Y+ + D+ + + RG V +D G +S
Sbjct: 1173 Q---TN---ITLQIATDEDSGILLYK-------GDKDHIAVELYRGRVRASYDTGSHPAS 1219
Query: 538 IVVDV-PINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGGIPS 711
+ V INDG H + L D LSVDG + K + +N DS +Y+GG+P
Sbjct: 1220 AIYSVETINDGNFH-IVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPG 1278
Query: 712 WLNIHGY---PG-----FIGCIENV 762
N+ PG F GCI N+
Sbjct: 1279 KSNVASLRQAPGQNGTSFHGCIRNL 1303
Score = 50.8 bits (116), Expect = 5e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 919 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 967
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
C C G+ G +C++ ++
Sbjct: 968 EGEEDGFWCICADGFEGENCEVNVD 992
Score = 46.8 bits (106), Expect = 9e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 912 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 950
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 990 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1040
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C + CDC GY G C + +
Sbjct: 1041 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1070
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 91.5 bits (217), Expect = 3e-18
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 18/265 (6%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPP---PPVNPCSL 183
D + +C+NG C T++ N CICP GY+G +CE SPP P +PC
Sbjct: 1076 DFDDCQDNKCKNGAHC-TDAVNGYTCICPEGYSGLFCE-------FSPPMVLPRTSPCDN 1127
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF-NGNGYVELPASLLRY 360
C+NG C N C C GY G C+ + SV F N Y+++P++ +R
Sbjct: 1128 FDCQNGAQCIVRIN---EPICQCLPGYQGEKCEKLV----SVNFINKESYLQIPSAKVRP 1180
Query: 361 DELASNPAVIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
+N I L + T D G+L Y+ + D+ + + RG V +D G +S
Sbjct: 1181 Q---TN---ITLQIATDEDSGILLYK-------GDKDHIAVELYRGRVRASYDTGSHPAS 1227
Query: 538 IVVDV-PINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGGIPS 711
+ V INDG H + L D LSVDG + K + +N DS +Y+GG+P
Sbjct: 1228 AIYSVETINDGNFH-IVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPG 1286
Query: 712 WLNIHGY---PG-----FIGCIENV 762
N+ PG F GCI N+
Sbjct: 1287 KSNVASLRQAPGQNGTSFHGCIRNL 1311
Score = 50.8 bits (116), Expect = 5e-06
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+N G+C+++ + C CP G+ G C+ P++ C +PC++GGTC
Sbjct: 927 CKNDGTCNSDPVDFYRCTCPYGFKGQDCDV-----------PIHACISNPCKHGGTCHLK 975
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
C C G+ G +C++ ++
Sbjct: 976 EGEEDGFWCICADGFEGENCEVNVD 1000
Score = 46.8 bits (106), Expect = 9e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NPC +PC+N GTC D + + C CP G+ G C +P+
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDF--YRCTCPYGFKGQDCDVPI 958
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/93 (27%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ E CEN +C N C+CPP YTG CE ++ L+PC+
Sbjct: 998 NVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQ---------DLNPCQ 1048
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C + CDC GY G C + +
Sbjct: 1049 HDSKCILTPKGF---KCDCTPGYVGEHCDIDFD 1078
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 90.2 bits (214), Expect = 7e-18
Identities = 79/269 (29%), Positives = 116/269 (43%), Gaps = 22/269 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-P 189
D E C++G +C C+C G+ G CE NPC L P
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------ENPCQLREP 4152
Query: 190 CRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQMPLE-------LGQ-SVGFNGNGYV 333
C +GGTC+ R + C G+ A LE GQ F+ +G++
Sbjct: 4153 CLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFL 4212
Query: 334 ELPASLLRYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEG-DYFLLRIERGFVVL 507
P + L P I L V T T G+L +Q +G D+ L ++ G +V
Sbjct: 4213 AFPGHVFSRS-LPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVF 4271
Query: 508 EWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADS 684
+ LG G + +V + PINDGE H+V A L E + VDG + S + G + +NA
Sbjct: 4272 RYQLGSGEARLVSEDPINDGEWHRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKG 4330
Query: 685 NIYIGGIPSWLNIHG---YPGFIGCIENV 762
++YIGG P + G G GC++N+
Sbjct: 4331 SVYIGGAPDVATLTGGRFSSGITGCVKNL 4359
Score = 83.4 bits (197), Expect = 8e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 3901
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 3902 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 3961
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 3962 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHR 4015
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 4016 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 4057
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 3848 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 3881
Score = 33.9 bits (74), Expect = 0.64
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +1
Query: 52 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 225
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1114 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1173
Query: 226 S---WMNHT----CD-CPLGYAG 270
+ +HT C+ C GY G
Sbjct: 1174 ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 826 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 869
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1628 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 31.1 bits (67), Expect = 4.5
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 261
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDP----VYGHCLNCQHN 786
Query: 262 YAGASC 279
G C
Sbjct: 787 TEGPQC 792
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 protein.
Length = 4391
Score = 90.2 bits (214), Expect = 7e-18
Identities = 79/269 (29%), Positives = 116/269 (43%), Gaps = 22/269 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-P 189
D E C++G +C C+C G+ G CE NPC L P
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------ENPCQLREP 4152
Query: 190 CRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQMPLE-------LGQ-SVGFNGNGYV 333
C +GGTC+ R + C G+ A LE GQ F+ +G++
Sbjct: 4153 CLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFL 4212
Query: 334 ELPASLLRYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEG-DYFLLRIERGFVVL 507
P + L P I L V T T G+L +Q +G D+ L ++ G +V
Sbjct: 4213 AFPGHVFSRS-LPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVF 4271
Query: 508 EWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADS 684
+ LG G + +V + PINDGE H+V A L E + VDG + S + G + +NA
Sbjct: 4272 RYQLGSGEARLVSEDPINDGEWHRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKG 4330
Query: 685 NIYIGGIPSWLNIHG---YPGFIGCIENV 762
++YIGG P + G G GC++N+
Sbjct: 4331 SVYIGGAPDVATLTGGRFSSGITGCVKNL 4359
Score = 83.4 bits (197), Expect = 8e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 3901
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 3902 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 3961
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 3962 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHR 4015
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 4016 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 4057
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 3848 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 3881
Score = 33.9 bits (74), Expect = 0.64
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +1
Query: 52 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 225
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1114 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1173
Query: 226 S---WMNHT----CD-CPLGYAG 270
+ +HT C+ C GY G
Sbjct: 1174 ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 826 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 869
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1628 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 261
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDP----VYGHCLNCQHN 786
Query: 262 YAGASC 279
G C
Sbjct: 787 TEGPQC 792
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 protein.
Length = 4391
Score = 90.2 bits (214), Expect = 7e-18
Identities = 79/269 (29%), Positives = 116/269 (43%), Gaps = 22/269 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-P 189
D E C++G +C C+C G+ G CE NPC L P
Sbjct: 4104 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------ENPCQLREP 4152
Query: 190 CRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQMPLE-------LGQ-SVGFNGNGYV 333
C +GGTC+ R + C G+ A LE GQ F+ +G++
Sbjct: 4153 CLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFL 4212
Query: 334 ELPASLLRYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEG-DYFLLRIERGFVVL 507
P + L P I L V T T G+L +Q +G D+ L ++ G +V
Sbjct: 4213 AFPGHVFSRS-LPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVF 4271
Query: 508 EWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADS 684
+ LG G + +V + PINDGE H+V A L E + VDG + S + G + +NA
Sbjct: 4272 RYQLGSGEARLVSEDPINDGEWHRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKG 4330
Query: 685 NIYIGGIPSWLNIHG---YPGFIGCIENV 762
++YIGG P + G G GC++N+
Sbjct: 4331 SVYIGGAPDVATLTGGRFSSGITGCVKNL 4359
Score = 83.4 bits (197), Expect = 8e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 3901
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 3902 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 3961
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 3962 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHR 4015
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 4016 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 4057
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 3848 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 3881
Score = 33.9 bits (74), Expect = 0.64
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +1
Query: 52 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 225
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1114 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1173
Query: 226 S---WMNHT----CD-CPLGYAG 270
+ +HT C+ C GY G
Sbjct: 1174 ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 826 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 869
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1628 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 261
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDP----VYGHCLNCQHN 786
Query: 262 YAGASC 279
G C
Sbjct: 787 TEGPQC 792
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 90.2 bits (214), Expect = 7e-18
Identities = 79/269 (29%), Positives = 116/269 (43%), Gaps = 22/269 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-P 189
D E C++G +C C+C G+ G CE NPC L P
Sbjct: 4083 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHE-----------ENPCQLREP 4131
Query: 190 CRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQMPLE-------LGQ-SVGFNGNGYV 333
C +GGTC+ R + C G+ A LE GQ F+ +G++
Sbjct: 4132 CLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFL 4191
Query: 334 ELPASLLRYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEG-DYFLLRIERGFVVL 507
P + L P I L V T T G+L +Q +G D+ L ++ G +V
Sbjct: 4192 AFPGHVFSRS-LPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVF 4250
Query: 508 EWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADS 684
+ LG G + +V + PINDGE H+V A L E + VDG + S + G + +NA
Sbjct: 4251 RYQLGSGEARLVSEDPINDGEWHRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKG 4309
Query: 685 NIYIGGIPSWLNIHG---YPGFIGCIENV 762
++YIGG P + G G GC++N+
Sbjct: 4310 SVYIGGAPDVATLTGGRFSSGITGCVKNL 4338
Score = 83.4 bits (197), Expect = 8e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 3832 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 3880
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 3881 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 3940
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 3941 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHR 3994
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 3995 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 4036
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 3827 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 3860
Score = 33.9 bits (74), Expect = 0.64
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +1
Query: 52 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 225
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1093 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1152
Query: 226 S---WMNHT----CD-CPLGYAG 270
+ +HT C+ C GY G
Sbjct: 1153 ACQGCQHHTEGPRCEQCQPGYYG 1175
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 805 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 848
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1607 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1647
Score = 31.1 bits (67), Expect = 4.5
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 2/66 (3%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 261
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 710 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDP----VYGHCLNCQHN 765
Query: 262 YAGASC 279
G C
Sbjct: 766 TEGPQC 771
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 89.0 bits (211), Expect = 2e-17
Identities = 80/269 (29%), Positives = 115/269 (42%), Gaps = 22/269 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-P 189
D E C++G +C C+C G G CE NPC L P
Sbjct: 4106 DSSPCERQPCQHGATCMPAGEYEFQCLCRDGIKGDLCEHE-----------ENPCQLREP 4154
Query: 190 CRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQMPLE-------LGQ-SVGFNGNGYV 333
C +GGTC+ R + C G+ A LE GQ F+ +G++
Sbjct: 4155 CLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFL 4214
Query: 334 ELPASLLRYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEG-DYFLLRIERGFVVL 507
P + L P I L V T T G+L +Q +G D+ L ++ G +V
Sbjct: 4215 AFPGHVFSRS-LPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVF 4273
Query: 508 EWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVD-KSAPATGISNVMNADS 684
+ LG G + +V + PINDGE H+V A L E + VDG + S + G + +NA
Sbjct: 4274 RYQLGSGEARLVSEDPINDGEWHRVTA-LREGRRGSIQVDGEELVSGRSPGPNVAVNAKG 4332
Query: 685 NIYIGGIPSWLNIHG---YPGFIGCIENV 762
+IYIGG P + G G GC++N+
Sbjct: 4333 SIYIGGAPDVATLTGGRFSSGITGCVKNL 4361
Score = 84.2 bits (199), Expect = 5e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 3855 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 3903
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 3904 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 3963
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 3964 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRTAEPLALGRWHR 4017
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 4018 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 4059
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 3850 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 3883
Score = 33.9 bits (74), Expect = 0.64
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Frame = +1
Query: 52 ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPP-PVNPCSLHPCR-NGGTCKPDRN 225
E G + E C CPPGY G C+ Y +P + C C + C+P+
Sbjct: 1116 ETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETG 1175
Query: 226 S---WMNHT----CD-CPLGYAG 270
+ +HT C+ C GY G
Sbjct: 1176 ACQGCQHHTEGPRCEQCQPGYYG 1198
Score = 31.5 bits (68), Expect = 3.4
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCR-NGGTCKPDRNSWMNHTCDCPLG 261
C CP GY+G CE+ A + P P + CS C + +C P H +C
Sbjct: 733 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCSCNGHASSCDP----VYGHCLNCQHN 788
Query: 262 YAGASCQ 282
G C+
Sbjct: 789 TEGPQCK 795
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 23/48 (47%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
S++C + G + ++ C PGYTG CE+ Y +P P C
Sbjct: 828 SDTCFLDTDGQATCDA----CAPGYTGRRCESCAPGYEGNPIQPGGKC 871
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
CE+ G+ T C PGYTG YCE Y+ +P C
Sbjct: 1630 CESLGAGGYRCT--ACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1670
>BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1192
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1193 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1246 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1305 LNG-TGFHGCIRNL 1317
Score = 60.5 bits (140), Expect = 6e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.052
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/70 (30%), Positives = 31/70 (44%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1356 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1402
Query: 250 CPLGYAGASC 279
C GY+GA C
Sbjct: 1403 CQDGYSGALC 1412
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 6.0
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 46 QCENGG--SCSTESTNCICPPGYTGSYCE 126
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1192
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1193 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1246 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1305 LNG-TGFHGCIRNL 1317
Score = 60.5 bits (140), Expect = 6e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.052
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/70 (30%), Positives = 31/70 (44%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1356 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1402
Query: 250 CPLGYAGASC 279
C GY+GA C
Sbjct: 1403 CQDGYSGALC 1412
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 6.0
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 46 QCENGG--SCSTESTNCICPPGYTGSYCE 126
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1192
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1193 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1246 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1305 LNG-TGFHGCIRNL 1317
Score = 60.5 bits (140), Expect = 6e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.052
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/77 (28%), Positives = 32/77 (41%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1356 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1402
Query: 250 CPLGYAGASCQMPLELG 300
C GY+GA C G
Sbjct: 1403 CQDGYSGALCNQSPSAG 1419
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
>AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1534
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1192
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1193 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1246 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1305 LNG-TGFHGCIRNL 1317
Score = 60.5 bits (140), Expect = 6e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.052
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/70 (30%), Positives = 31/70 (44%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1356 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1402
Query: 250 CPLGYAGASC 279
C GY+GA C
Sbjct: 1403 CQDGYSGALC 1412
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 6.0
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 46 QCENGG--SCSTESTNCICPPGYTGSYCE 126
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosophila)
protein.
Length = 1461
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1192
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1193 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1246 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1305 LNG-TGFHGCIRNL 1317
Score = 60.5 bits (140), Expect = 6e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 979
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 37.5 bits (83), Expect = 0.052
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 966
Score = 35.5 bits (78), Expect = 0.21
Identities = 22/77 (28%), Positives = 32/77 (41%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1356 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1402
Query: 250 CPLGYAGASCQMPLELG 300
C GY+GA C G
Sbjct: 1403 CQDGYSGALCNQSPSAG 1419
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1091 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1145
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1146 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1192
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1193 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1246 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1305 LNG-TGFHGCIRNL 1317
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + N CS PC NGGTC
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSL-----------NSCSSGPCENGGTC 979
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 980 HAQEGEDAPFTCSCPTGFEGPTC 1002
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 965 LNSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1013
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1014 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1046
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1045 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1093
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1094 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1124
Score = 36.7 bits (81), Expect = 0.091
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C PC+N GTC D + C CP GY G C++ L
Sbjct: 929 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSL 965
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/70 (30%), Positives = 31/70 (44%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1356 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1402
Query: 250 CPLGYAGASC 279
C GY+GA C
Sbjct: 1403 CQDGYSGALC 1412
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1132 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 30.7 bits (66), Expect = 6.0
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 46 QCENGG--SCSTESTNCICPPGYTGSYCE 126
QC +G + T+ +C+C PG++G CE
Sbjct: 1426 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 84.6 bits (200), Expect = 3e-16
Identities = 77/254 (30%), Positives = 115/254 (45%), Gaps = 15/254 (5%)
Frame = +1
Query: 46 QCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C+NG C E S +C+C GY+G CE I +L P P +PC C+NG C
Sbjct: 1175 RCQNGAQCMDEVNSYSCLCAEGYSGQLCE--IPPHL---PAPKSPCEGTECQNGANCVDQ 1229
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNP-AVIAL 396
N C C G+ G C+ L SV F + L++ +L + P A I L
Sbjct: 1230 GN---RPVCQCLPGFGGPECEKLL----SVNFVDRD------TYLQFTDLQNWPRANITL 1276
Query: 397 AVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PINDGE 570
V T D G+L Y + D+ + + +G V + +D G SS + INDG+
Sbjct: 1277 QVSTAEDNGILLYN-------GDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1329
Query: 571 RHQVAARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIP---------SWLN 720
H V + D LS+D G + G +N+++ +Y+GG+P W
Sbjct: 1330 FHTVEL-VAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQI 1388
Query: 721 IHGYPGFIGCIENV 762
++G GF GCI N+
Sbjct: 1389 LNG-TGFHGCIRNL 1401
Score = 60.5 bits (140), Expect = 6e-09
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Frame = +1
Query: 40 SCQCENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C E C CP GY G CE + S CS PC NGGTC
Sbjct: 1015 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDS-----------CSSGPCENGGTC 1063
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
TC CP G+ G +C
Sbjct: 1064 HAQEGEDAPFTCSCPTGFEGPTC 1086
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 5/96 (5%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
+ + S CENGG+C + C CP G+ G C + C H
Sbjct: 1049 LDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVN-----------TDDCVDHA 1097
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C NGG C N+TC CPL Y G +C+ ++L
Sbjct: 1098 CANGGVCVDGVG---NYTCQCPLQYEGKACEQLVDL 1130
Score = 45.2 bits (102), Expect = 3e-04
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ + + C++ C + + C C PGY G C + C H C+
Sbjct: 1129 DLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSEN-----------QDDCRDHRCQ 1177
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
NG C + NS ++C C GY+G C++P L
Sbjct: 1178 NGAQCMDEVNS---YSCLCAEGYSGQLCEIPPHL 1208
Score = 37.5 bits (83), Expect = 0.052
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC+N GTC D + C CP GY G C++ L+
Sbjct: 1013 CLSSPCQNQGTCHNDPLEV--YRCACPSGYKGRDCEVSLD 1050
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/70 (30%), Positives = 31/70 (44%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
+T C C G+ G +C+ P PC H C +G C P ++++C
Sbjct: 1440 ATPGPMCHCEAGWVGLHCDQ----------PADGPCHGHKCVHG-QCVP--LDALSYSCQ 1486
Query: 250 CPLGYAGASC 279
C GY+GA C
Sbjct: 1487 CQDGYSGALC 1496
Score = 31.5 bits (68), Expect = 3.4
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
E +C+NG +C + C C PG+ G CE
Sbjct: 1216 EGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1247
Score = 30.7 bits (66), Expect = 6.0
Identities = 11/29 (37%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 46 QCENGG--SCSTESTNCICPPGYTGSYCE 126
QC +G + T+ +C+C PG++G CE
Sbjct: 1510 QCLHGHCQASGTKGAHCVCDPGFSGELCE 1538
>BC109204-1|AAI09205.1| 351|Homo sapiens HSPG2 protein protein.
Length = 351
Score = 83.4 bits (197), Expect = 8e-16
Identities = 72/226 (31%), Positives = 111/226 (49%), Gaps = 7/226 (3%)
Frame = +1
Query: 49 CENGGSC-STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG C +ES++ C+CP G+TGS CE A + C C TC +
Sbjct: 88 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH----------CHPEACGPDATC-VN 136
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALA 399
R +TC C LG +G C+ + + Y+ LPA + EL + LA
Sbjct: 137 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLA 196
Query: 400 VHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQ 579
DGVL + G++ P E D+ L + G + ++LG GL+ + P+ G H+
Sbjct: 197 ----PDGVLLFS-GGKSGPVE-DFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHR 250
Query: 580 VAA-RLHEDGHAWLSVDG---VDKSAPATGISNVMNADSNIYIGGI 705
V+A RL++DG L V+G V +S+P G S +N + +Y+GG+
Sbjct: 251 VSAERLNKDGS--LRVNGGRPVLRSSP--GKSQGLNLHTLLYLGGV 292
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC+NGG C +S ++ C CP G+ G+ C+
Sbjct: 83 CRDRPCQNGGQCHDSESS--SYVCVCPAGFTGSRCE 116
>BC126313-1|AAI26314.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/97 (38%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC--------SL 183
Q S+ C C NGG CS + C C PGY G C+ R+ + P PC S
Sbjct: 313 QCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISC 372
Query: 184 HPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 373 HPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 406
Score = 70.9 bits (166), Expect = 5e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 240
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
+ C CP G+ GA C P G
Sbjct: 241 --HHITGECACPPGWTGAVCAQPCPPG 265
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 460
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C +P G + G N N
Sbjct: 461 ---VDGSCTCKEGWQGLDCTLPCPSG-TWGLNCN 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 216
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 232 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 283
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF 315
+ C C GY G CQ G S GF
Sbjct: 284 ---DHVTGQCHCTAGYMGDRCQEECPFG-SFGF 312
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 585
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
+C P+ S C+C G+ G CQ
Sbjct: 586 SCSPEDGS-----CECAPGFRGPLCQ 606
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 576 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 630
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P + ++ C+C G++GA C
Sbjct: 631 PCHH--ISGICECLPGFSGALC 650
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 216
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 709 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 761
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
++ C C G+ G C+
Sbjct: 762 ---DHISGKCTCRTGFTGQHCE 780
Score = 52.0 bits (119), Expect = 2e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 219
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 804
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+ TC C G+ G C
Sbjct: 805 --DHVTGTCYCSPGFKGIRC 822
Score = 50.8 bits (116), Expect = 5e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 197
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P C C GY G C+
Sbjct: 198 DPRAGE-----CLCAPGYTGVYCE 216
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/95 (30%), Positives = 41/95 (43%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 447 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 502
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
P ++ +C C G+ G +C++P G + G N
Sbjct: 503 P-----IDGSCSCTPGWLGDTCELPCPDG-TFGLN 531
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 272 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 326
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + C+C GY G CQ
Sbjct: 327 SPTTGA-----CECEPGYKGPRCQ 345
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 541
Query: 202 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 285
C P W CD CP G G +C +
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 207
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 664 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 717
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C + + C C G+ G C
Sbjct: 718 CSAE-----DGACHCTPGWTGLFC 736
Score = 33.5 bits (73), Expect = 0.85
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
C+C N +C + C C PG+ G C+
Sbjct: 796 CECMNNSTCDHVTGTCYCSPGFKGIRCD 823
>BC117419-1|AAI17420.1| 1044|Homo sapiens MEGF11 protein protein.
Length = 1044
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/97 (38%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC--------SL 183
Q S+ C C NGG CS + C C PGY G C+ R+ + P PC S
Sbjct: 313 QCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISC 372
Query: 184 HPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 373 HPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 406
Score = 70.9 bits (166), Expect = 5e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 240
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
+ C CP G+ GA C P G
Sbjct: 241 --HHITGECACPPGWTGAVCAQPCPPG 265
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 460
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C +P G + G N N
Sbjct: 461 ---VDGSCTCKEGWQGLDCTLPCPSG-TWGLNCN 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 216
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 232 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 283
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF 315
+ C C GY G CQ G S GF
Sbjct: 284 ---DHVTGQCHCTAGYMGDRCQEECPFG-SFGF 312
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 585
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
+C P+ S C+C G+ G CQ
Sbjct: 586 SCSPEDGS-----CECAPGFRGPLCQ 606
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 576 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 630
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P + ++ C+C G++GA C
Sbjct: 631 PCHH--ISGICECLPGFSGALC 650
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 216
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 709 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 761
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
++ C C G+ G C+
Sbjct: 762 ---DHISGKCTCRTGFTGQHCE 780
Score = 52.0 bits (119), Expect = 2e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 219
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 804
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+ TC C G+ G C
Sbjct: 805 --DHVTGTCYCSPGFKGIRC 822
Score = 50.8 bits (116), Expect = 5e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 197
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P C C GY G C+
Sbjct: 198 DPRAGE-----CLCAPGYTGVYCE 216
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/95 (30%), Positives = 41/95 (43%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 447 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 502
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
P ++ +C C G+ G +C++P G + G N
Sbjct: 503 P-----IDGSCSCTPGWLGDTCELPCPDG-TFGLN 531
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 272 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 326
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + C+C GY G CQ
Sbjct: 327 SPTTGA-----CECEPGYKGPRCQ 345
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 541
Query: 202 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 285
C P W CD CP G G +C +
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 207
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 664 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 717
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C + + C C G+ G C
Sbjct: 718 CSAE-----DGACHCTPGWTGLFC 736
Score = 33.5 bits (73), Expect = 0.85
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
C+C N +C + C C PG+ G C+
Sbjct: 796 CECMNNSTCDHVTGTCYCSPGFKGIRCD 823
>AL834326-1|CAD38994.1| 626|Homo sapiens hypothetical protein
protein.
Length = 626
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/97 (38%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC--------SL 183
Q S+ C C NGG CS + C C PGY G C+ R+ + P PC S
Sbjct: 64 QCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISC 123
Query: 184 HPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 124 HPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 157
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 158 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 211
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C +P G + G N N
Sbjct: 212 ---VDGSCTCKEGWQGLDCTLPCPSG-TWGLNCN 241
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 281 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 336
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
+C P+ S C+C G+ G CQ
Sbjct: 337 SCSPEDGS-----CECAPGFRGPLCQ 357
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 327 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 381
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P + ++ C+C G++GA C
Sbjct: 382 PCHH--ISGICECLPGFSGALC 401
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/95 (30%), Positives = 41/95 (43%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 198 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 253
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
P ++ +C C G+ G +C++P G + G N
Sbjct: 254 P-----IDGSCSCTPGWLGDTCELPCPDG-TFGLN 282
Score = 50.4 bits (115), Expect = 7e-06
Identities = 21/48 (43%), Positives = 25/48 (52%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
+C C NG SCS E C C PG+TG +C R L S P + C L
Sbjct: 460 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRKPHLLASQPLRIPCCGL 507
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 23 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 77
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + C+C GY G CQ
Sbjct: 78 SPTTGA-----CECEPGYKGPRCQ 96
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 238 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 292
Query: 202 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 285
C P W CD CP G G +C +
Sbjct: 293 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 328
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 207
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 415 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 468
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C + + C C G+ G C
Sbjct: 469 CSAE-----DGACHCTPGWTGLFC 487
>AB300051-1|BAF64841.1| 1044|Homo sapiens MEGF11 protein.
Length = 1044
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/97 (38%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC--------SL 183
Q S+ C C NGG CS + C C PGY G C+ R+ + P PC S
Sbjct: 313 QCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISC 372
Query: 184 HPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 373 HPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 406
Score = 70.9 bits (166), Expect = 5e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 189 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 240
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
+ C CP G+ GA C P G
Sbjct: 241 --HHITGECACPPGWTGAVCAQPCPPG 265
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 407 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 460
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C +P G + G N N
Sbjct: 461 ---VDGSCTCKEGWQGLDCTLPCPSG-TWGLNCN 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 216
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 232 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 283
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF 315
+ C C GY G CQ G S GF
Sbjct: 284 ---DHVTGQCHCTAGYMGDRCQEECPFG-SFGF 312
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 585
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
+C P+ S C+C G+ G CQ
Sbjct: 586 SCSPEDGS-----CECAPGFRGPLCQ 606
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 576 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 630
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P + ++ C+C G++GA C
Sbjct: 631 PCHH--ISGICECLPGFSGALC 650
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 216
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 709 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 761
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
++ C C G+ G C+
Sbjct: 762 ---DHISGKCTCRTGFTGQHCE 780
Score = 52.0 bits (119), Expect = 2e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 219
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 804
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+ TC C G+ G C
Sbjct: 805 --DHVTGTCYCSPGFKGIRC 822
Score = 50.8 bits (116), Expect = 5e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 197
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P C C GY G C+
Sbjct: 198 DPRAGE-----CLCAPGYTGVYCE 216
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/95 (30%), Positives = 41/95 (43%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 447 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 502
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
P ++ +C C G+ G +C++P G + G N
Sbjct: 503 P-----IDGSCSCTPGWLGDTCELPCPDG-TFGLN 531
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 272 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 326
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + C+C GY G CQ
Sbjct: 327 SPTTGA-----CECEPGYKGPRCQ 345
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 541
Query: 202 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 285
C P W CD CP G G +C +
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 577
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 207
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 664 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 717
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C + + C C G+ G C
Sbjct: 718 CSAE-----DGACHCTPGWTGLFC 736
Score = 33.5 bits (73), Expect = 0.85
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
C+C N +C + C C PG+ G C+
Sbjct: 796 CECMNNSTCDHVTGTCYCSPGFKGIRCD 823
>AB058677-1|BAB47410.1| 969|Homo sapiens MEGF11 protein (KIAA1781)
protein.
Length = 969
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/97 (38%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC--------SL 183
Q S+ C C NGG CS + C C PGY G C+ R+ + P PC S
Sbjct: 238 QCSQRCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISC 297
Query: 184 HPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
HP TC+P W H C+ CP+GY G CQ+P
Sbjct: 298 HPVTGACTCQP---GWSGHHCNESCPVGYYGDGCQLP 331
Score = 70.9 bits (166), Expect = 5e-12
Identities = 36/87 (41%), Positives = 42/87 (48%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
CQC +G SC + C+C PGYTG YCE L P C L PC+NGGTC
Sbjct: 114 CQCRHGASCDPRAGECLCAPGYTGVYCEE-----LCPPGSHGAHCELRCPCQNGGTC--- 165
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
+ C CP G+ GA C P G
Sbjct: 166 --HHITGECACPPGWTGAVCAQPCPPG 190
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/94 (34%), Positives = 44/94 (46%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+NG C + + C C PG+ G C A+ P N S+ C NGGTC P
Sbjct: 332 CTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP----NCSSICSCNNGGTCSP-- 385
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C +P G + G N N
Sbjct: 386 ---VDGSCTCKEGWQGLDCTLPCPSG-TWGLNCN 415
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/93 (36%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKP 216
C C+NGG+C + C CPPG+TG+ C PP CS PC +GG C
Sbjct: 157 CPCQNGGTCHHITGECACPPGWTGAVCAQPC------PPGTFGQNCSQDCPCHHGGQC-- 208
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF 315
+ C C GY G CQ G S GF
Sbjct: 209 ---DHVTGQCHCTAGYMGDRCQEECPFG-SFGF 237
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 40/86 (46%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ SE C C + C + +C C G+TG C++ P V+ CS C NGG
Sbjct: 455 LNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS-CS---CENGG 510
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
+C P+ S C+C G+ G CQ
Sbjct: 511 SCSPEDGS-----CECAPGFRGPLCQ 531
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/82 (37%), Positives = 43/82 (52%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S SC CENGGSCS E +C C PG+ G C+ RI PC L C + + +
Sbjct: 501 SVSCSCENGGSCSPEDGSCECAPGFRGPLCQ-RICPPGFYGHGCAQPCPL--CVH--SSR 555
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P + ++ C+C G++GA C
Sbjct: 556 PCHH--ISGICECLPGFSGALC 575
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS-LHPCRNGGTCKP 216
+C C NG SCS E C C PG+TG +C R + C + C+NG +C
Sbjct: 634 ACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG-----KDCGRVCQCQNGASC-- 686
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
++ C C G+ G C+
Sbjct: 687 ---DHISGKCTCRTGFTGQHCE 705
Score = 52.0 bits (119), Expect = 2e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTCKPD 219
CQC+NG SC S C C G+TG +CE R A P C L C N TC
Sbjct: 678 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-----PGTFGYGCQQLCECMNNSTC--- 729
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+ TC C G+ G C
Sbjct: 730 --DHVTGTCYCSPGFKGIRC 747
Score = 50.8 bits (116), Expect = 5e-06
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S CQC+NG C+ + C+C G+ G CE L +P C L CR+G +C
Sbjct: 68 SNRCQCQNGALCNPITGACVCAAGFRGWRCEE-----LCAPGTHGKGCQLPCQCRHGASC 122
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P C C GY G C+
Sbjct: 123 DPRAGE-----CLCAPGYTGVYCE 141
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/95 (30%), Positives = 41/95 (43%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C C NGG+CS +C C G+ G C S +N C NG C
Sbjct: 372 SSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWG----LNCNESCTCANGAACS 427
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
P ++ +C C G+ G +C++P G + G N
Sbjct: 428 P-----IDGSCSCTPGWLGDTCELPCPDG-TFGLN 456
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTC 210
S+ C C +GG C + C C GY G C+ CS C NGG C
Sbjct: 197 SQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG-----FQCSQRCDCHNGGQC 251
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + C+C GY G CQ
Sbjct: 252 SPTTGA-----CECEPGYKGPRCQ 270
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 9/96 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
+ +ESC C NG +CS +C C PG+ G CE +N CS H C +
Sbjct: 412 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG----LN-CSEHCDCSHA 466
Query: 202 GTCKPDRN------SWMNHTCD--CPLGYAGASCQM 285
C P W CD CP G G +C +
Sbjct: 467 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV 502
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH--PCRNGGT 207
++ C C N G+CS +C C PG+ G C PP P H C NG +
Sbjct: 589 AQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ------ACPPGFWGPACFHACSCHNGAS 642
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C + + C C G+ G C
Sbjct: 643 CSAE-----DGACHCTPGWTGLFC 661
Score = 33.5 bits (73), Expect = 0.85
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
C+C N +C + C C PG+ G C+
Sbjct: 721 CECMNNSTCDHVTGTCYCSPGFKGIRCD 748
>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosophila)
protein.
Length = 1523
Score = 74.5 bits (175), Expect = 4e-13
Identities = 77/258 (29%), Positives = 114/258 (44%), Gaps = 19/258 (7%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 207
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1133
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNG-NGYVELPASLLRYDELASNPA 384
C + TC CP G+AG C+ + +V F G + YVEL ++ +R A
Sbjct: 1134 CIVVQ---QEPTCRCPPGFAGPRCEKLI----TVNFVGKDSYVELASAKVR------PQA 1180
Query: 385 VIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PI 558
I+L V T D G+L Y+ + D L + +G V L +D + V V +
Sbjct: 1181 NISLQVATDKDNGILLYK-------GDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETV 1233
Query: 559 NDGERHQV-AARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIPSWLNIHG- 729
NDG+ H V L++ + L VD G KS + +S +Y+GGIP+ +
Sbjct: 1234 NDGQFHSVELVTLNQTLN--LVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSAL 1291
Query: 730 -------YPGFIGCIENV 762
GF GCI V
Sbjct: 1292 RQGTDRPLGGFHGCIHEV 1309
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 40 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 970
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
+ +C CPLG+ G C++
Sbjct: 971 HLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1045 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1093
Query: 223 NSWMNHTCDCPLGYAGASCQMP 288
N +TC CP G++G C+ P
Sbjct: 1094 N---GYTCTCPQGFSGPFCEHP 1112
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1001 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1051
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + +C+C GY+G C+
Sbjct: 1052 IPLDKGF---SCECVPGYSGKLCE 1072
Score = 39.9 bits (89), Expect = 0.010
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 918 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 956
Score = 37.1 bits (82), Expect = 0.069
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Frame = +1
Query: 37 ESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+SC C++G S +S C C PG+TG C+ +PC H C + G
Sbjct: 1333 KSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGHRCHH-GK 1381
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C S+M C C GY G C
Sbjct: 1382 CVATGTSYM---CKCAEGYGGDLC 1402
Score = 33.9 bits (74), Expect = 0.64
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%)
Frame = +1
Query: 22 DIQASESC---QCENGGSCST-ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
D +A + C +C +G +T S C C GY G C+ + S N CS
Sbjct: 1365 DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS--------ANACSAFK 1416
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSV 309
C +G D+ C C G++G CQ LGQ V
Sbjct: 1417 CHHGQCHISDQG---EPYCLCQPGFSGEHCQQENPCLGQVV 1454
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 74.5 bits (175), Expect = 4e-13
Identities = 77/258 (29%), Positives = 114/258 (44%), Gaps = 19/258 (7%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 207
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1133
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNG-NGYVELPASLLRYDELASNPA 384
C + TC CP G+AG C+ + +V F G + YVEL ++ +R A
Sbjct: 1134 CIVVQ---QEPTCRCPPGFAGPRCEKLI----TVNFVGKDSYVELASAKVR------PQA 1180
Query: 385 VIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PI 558
I+L V T D G+L Y+ + D L + +G V L +D + V V +
Sbjct: 1181 NISLQVATDKDNGILLYK-------GDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETV 1233
Query: 559 NDGERHQV-AARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIPSWLNIHG- 729
NDG+ H V L++ + L VD G KS + +S +Y+GGIP+ +
Sbjct: 1234 NDGQFHSVELVTLNQTLN--LVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSAL 1291
Query: 730 -------YPGFIGCIENV 762
GF GCI V
Sbjct: 1292 RQGTDRPLGGFHGCIHEV 1309
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 40 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 970
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
+ +C CPLG+ G C++
Sbjct: 971 HLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1045 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1093
Query: 223 NSWMNHTCDCPLGYAGASCQMP 288
N +TC CP G++G C+ P
Sbjct: 1094 N---GYTCTCPQGFSGPFCEHP 1112
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1001 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1051
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + +C+C GY+G C+
Sbjct: 1052 IPLDKGF---SCECVPGYSGKLCE 1072
Score = 39.9 bits (89), Expect = 0.010
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 918 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 956
Score = 37.1 bits (82), Expect = 0.069
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Frame = +1
Query: 37 ESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+SC C++G S +S C C PG+TG C+ +PC H C + G
Sbjct: 1333 KSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGHRCHH-GK 1381
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C S+M C C GY G C
Sbjct: 1382 CVATGTSYM---CKCAEGYGGDLC 1402
Score = 33.9 bits (74), Expect = 0.64
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%)
Frame = +1
Query: 22 DIQASESC---QCENGGSCST-ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
D +A + C +C +G +T S C C GY G C+ + S N CS
Sbjct: 1365 DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS--------ANACSAFK 1416
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSV 309
C +G D+ C C G++G CQ LGQ V
Sbjct: 1417 CHHGQCHISDQG---EPYCLCQPGFSGEHCQQENPCLGQVV 1454
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 74.5 bits (175), Expect = 4e-13
Identities = 77/258 (29%), Positives = 114/258 (44%), Gaps = 19/258 (7%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 207
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1082 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1133
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNG-NGYVELPASLLRYDELASNPA 384
C + TC CP G+AG C+ + +V F G + YVEL ++ +R A
Sbjct: 1134 CIVVQ---QEPTCRCPPGFAGPRCEKLI----TVNFVGKDSYVELASAKVR------PQA 1180
Query: 385 VIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PI 558
I+L V T D G+L Y+ + D L + +G V L +D + V V +
Sbjct: 1181 NISLQVATDKDNGILLYK-------GDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETV 1233
Query: 559 NDGERHQV-AARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIPSWLNIHG- 729
NDG+ H V L++ + L VD G KS + +S +Y+GGIP+ +
Sbjct: 1234 NDGQFHSVELVTLNQTLN--LVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSAL 1291
Query: 730 -------YPGFIGCIENV 762
GF GCI V
Sbjct: 1292 RQGTDRPLGGFHGCIHEV 1309
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 40 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 970
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
+ +C CPLG+ G C++
Sbjct: 971 HLSDSHKDGFSCSCPLGFEGQRCEI 995
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1045 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1093
Query: 223 NSWMNHTCDCPLGYAGASCQMP 288
N +TC CP G++G C+ P
Sbjct: 1094 N---GYTCTCPQGFSGPFCEHP 1112
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1001 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1051
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + +C+C GY+G C+
Sbjct: 1052 IPLDKGF---SCECVPGYSGKLCE 1072
Score = 39.9 bits (89), Expect = 0.010
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 918 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 956
Score = 37.1 bits (82), Expect = 0.069
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Frame = +1
Query: 37 ESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+SC C++G S +S C C PG+TG C+ +PC H C + G
Sbjct: 1333 KSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGHRCHH-GK 1381
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C S+M C C GY G C
Sbjct: 1382 CVATGTSYM---CKCAEGYGGDLC 1402
Score = 33.9 bits (74), Expect = 0.64
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%)
Frame = +1
Query: 22 DIQASESC---QCENGGSCST-ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
D +A + C +C +G +T S C C GY G C+ + S N CS
Sbjct: 1365 DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS--------ANACSAFK 1416
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSV 309
C +G D+ C C G++G CQ LGQ V
Sbjct: 1417 CHHGQCHISDQG---EPYCLCQPGFSGEHCQQENPCLGQVV 1454
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 74.5 bits (175), Expect = 4e-13
Identities = 77/258 (29%), Positives = 114/258 (44%), Gaps = 19/258 (7%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPV----NPCSLHPCRNGGT 207
+C +G C + C CP G++G +CE PPP V +PC + C+NG
Sbjct: 1118 KCRHGAQCVDTINGYTCTCPQGFSGPFCE--------HPPPMVLLQTSPCDQYECQNGAQ 1169
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNG-NGYVELPASLLRYDELASNPA 384
C + TC CP G+AG C+ + +V F G + YVEL ++ +R A
Sbjct: 1170 CIVVQ---QEPTCRCPPGFAGPRCEKLI----TVNFVGKDSYVELASAKVR------PQA 1216
Query: 385 VIALAVHTTND-GVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDV-PI 558
I+L V T D G+L Y+ + D L + +G V L +D + V V +
Sbjct: 1217 NISLQVATDKDNGILLYK-------GDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETV 1269
Query: 559 NDGERHQV-AARLHEDGHAWLSVD-GVDKSAPATGISNVMNADSNIYIGGIPSWLNIHG- 729
NDG+ H V L++ + L VD G KS + +S +Y+GGIP+ +
Sbjct: 1270 NDGQFHSVELVTLNQTLN--LVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSAL 1327
Query: 730 -------YPGFIGCIENV 762
GF GCI V
Sbjct: 1328 RQGTDRPLGGFHGCIHEV 1345
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 40 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 958 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 1006
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
+ +C CPLG+ G C++
Sbjct: 1007 HLSDSHKDGFSCSCPLGFEGQRCEI 1031
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 2/82 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ C + +C C PGY+G CET + C H CR+G C
Sbjct: 1081 CQHEAKCIPLDKGFSCECVPGYSGKLCET-----------DNDDCVAHKCRHGAQCVDTI 1129
Query: 223 NSWMNHTCDCPLGYAGASCQMP 288
N +TC CP G++G C+ P
Sbjct: 1130 N---GYTCTCPQGFSGPFCEHP 1148
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E CEN +C N CICPP YTG C+ I + P +N C H + C
Sbjct: 1037 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCV----PELNLCQ-HEAK----C 1087
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
P + +C+C GY+G C+
Sbjct: 1088 IPLDKGF---SCECVPGYSGKLCE 1108
Score = 39.9 bits (89), Expect = 0.010
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 954 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 992
Score = 37.1 bits (82), Expect = 0.069
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Frame = +1
Query: 37 ESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+SC C++G S +S C C PG+TG C+ +PC H C + G
Sbjct: 1369 KSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGHRCHH-GK 1417
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C S+M C C GY G C
Sbjct: 1418 CVATGTSYM---CKCAEGYGGDLC 1438
Score = 33.9 bits (74), Expect = 0.64
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%)
Frame = +1
Query: 22 DIQASESC---QCENGGSCST-ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
D +A + C +C +G +T S C C GY G C+ + S N CS
Sbjct: 1401 DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS--------ANACSAFK 1452
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSV 309
C +G D+ C C G++G CQ LGQ V
Sbjct: 1453 CHHGQCHISDQG---EPYCLCQPGFSGEHCQQENPCLGQVV 1490
>AL645608-13|CAI15575.2| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/192 (30%), Positives = 86/192 (44%), Gaps = 6/192 (3%)
Frame = +1
Query: 151 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSV-GFNGNG 327
+P P PC PC +GGTC+ D TC CP G GA C+ LG V F G
Sbjct: 1325 APQQPPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCEK--VLGAPVPAFEGRS 1381
Query: 328 YVELPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
++ P +L Y L +AL G+L Y + D+ L + G V
Sbjct: 1382 FLAFP-TLRAYHTLR-----LALEFRALEPQGLLLYNGNARGK----DFLALALLDGRVQ 1431
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGIS----NVM 672
L +D G G + + VP+ G+ H++ H LSVDG P G S + +
Sbjct: 1432 LRFDTGSGPAVLTSAVPVEPGQWHRLELSRHW-RRGTLSVDG---ETPVLGESPSGTDGL 1487
Query: 673 NADSNIYIGGIP 708
N D+++++GG+P
Sbjct: 1488 NLDTDLFVGGVP 1499
Score = 62.5 bits (145), Expect = 2e-09
Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 15/215 (6%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL---ELG--QSVGFNGNG 327
P S HPC NG +C P +++ C CP G++G C+ L G ++ F+G
Sbjct: 1817 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 1873
Query: 328 YVELPASLLRYDE-LASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
+VE ++ ++ L SN ++L T VL G+A DY L I G +
Sbjct: 1874 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVL---WSGKA-TERADYVALAIVDGHLQ 1929
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNV----M 672
L ++LG + VP+N +V A E L V AP TG S + +
Sbjct: 1930 LSYNLGSQPVVLRSTVPVNTNRWLRVVAH-REQREGSLQ---VGNEAPVTGSSPLGATQL 1985
Query: 673 NADSNIYIGGIPSWLNIHGYP-----GFIGCIENV 762
+ D +++GG+P P GF+GC+ +V
Sbjct: 1986 DTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDV 2020
Score = 60.9 bits (141), Expect = 5e-09
Identities = 57/231 (24%), Positives = 86/231 (37%), Gaps = 9/231 (3%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-- 213
C G C +C CPPG G C +PC +PC C+
Sbjct: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-----------KSPCQPNPCHGAAPCRVL 1606
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS----VGFNGNGYVELPASLLRYDELASNP 381
P+ + C+CPLG G CQ S FNG ++EL +L
Sbjct: 1607 PEGGA----QCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKM 1662
Query: 382 AVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPIN 561
A+ + + G+L Y GQ +GD+ L + + +DLG G + I P+
Sbjct: 1663 ALEVVFLARGPSGLLLY--NGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVT 1720
Query: 562 DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
G +V+ + A DG + V+N +Y+GG P +
Sbjct: 1721 LGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDF 1771
Score = 34.3 bits (75), Expect = 0.49
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 7/87 (8%)
Frame = +1
Query: 40 SCQCEN----GGSCSTESTNCICPPGYTG---SYCETRIASYLMSPPPPVNPCSLHPCRN 198
+CQC GG+C + C C PG G CE ++ + C+ C
Sbjct: 792 ACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDP 851
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASC 279
G + D M C C G AG C
Sbjct: 852 QGAVRDDCEQ-MTGLCSCKPGVAGPKC 877
Score = 31.9 bits (69), Expect = 2.6
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCE 126
C NG SC C+CP G++G +CE
Sbjct: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
Score = 30.3 bits (65), Expect = 7.9
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC G C+ + + H C CP G G +C
Sbjct: 1551 HPCLPNPCHGGAPCQ-NLEAGRFH-CQCPPGRVGPTC 1585
>AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein.
Length = 2026
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/192 (30%), Positives = 86/192 (44%), Gaps = 6/192 (3%)
Frame = +1
Query: 151 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSV-GFNGNG 327
+P P PC PC +GGTC+ D TC CP G GA C+ LG V F G
Sbjct: 1306 APQQPPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCEK--VLGAPVPAFEGRS 1362
Query: 328 YVELPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
++ P +L Y L +AL G+L Y + D+ L + G V
Sbjct: 1363 FLAFP-TLRAYHTLR-----LALEFRALEPQGLLLYNGNARGK----DFLALALLDGRVQ 1412
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGIS----NVM 672
L +D G G + + VP+ G+ H++ H LSVDG P G S + +
Sbjct: 1413 LRFDTGSGPAVLTSAVPVEPGQWHRLELSRHW-RRGTLSVDG---ETPVLGESPSGTDGL 1468
Query: 673 NADSNIYIGGIP 708
N D+++++GG+P
Sbjct: 1469 NLDTDLFVGGVP 1480
Score = 62.5 bits (145), Expect = 2e-09
Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 15/215 (6%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL---ELG--QSVGFNGNG 327
P S HPC NG +C P +++ C CP G++G C+ L G ++ F+G
Sbjct: 1798 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 1854
Query: 328 YVELPASLLRYDE-LASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
+VE ++ ++ L SN ++L T VL G+A DY L I G +
Sbjct: 1855 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVL---WSGKA-TERADYVALAIVDGHLQ 1910
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNV----M 672
L ++LG + VP+N +V A E L V AP TG S + +
Sbjct: 1911 LSYNLGSQPVVLRSTVPVNTNRWLRVVAH-REQREGSLQ---VGNEAPVTGSSPLGATQL 1966
Query: 673 NADSNIYIGGIPSWLNIHGYP-----GFIGCIENV 762
+ D +++GG+P P GF+GC+ +V
Sbjct: 1967 DTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDV 2001
Score = 60.9 bits (141), Expect = 5e-09
Identities = 57/231 (24%), Positives = 86/231 (37%), Gaps = 9/231 (3%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-- 213
C G C +C CPPG G C +PC +PC C+
Sbjct: 1539 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-----------KSPCQPNPCHGAAPCRVL 1587
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS----VGFNGNGYVELPASLLRYDELASNP 381
P+ + C+CPLG G CQ S FNG ++EL +L
Sbjct: 1588 PEGGA----QCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKM 1643
Query: 382 AVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPIN 561
A+ + + G+L Y GQ +GD+ L + + +DLG G + I P+
Sbjct: 1644 ALEVVFLARGPSGLLLY--NGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVT 1701
Query: 562 DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
G +V+ + A DG + V+N +Y+GG P +
Sbjct: 1702 LGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDF 1752
Score = 34.3 bits (75), Expect = 0.49
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 7/87 (8%)
Frame = +1
Query: 40 SCQCEN----GGSCSTESTNCICPPGYTG---SYCETRIASYLMSPPPPVNPCSLHPCRN 198
+CQC GG+C + C C PG G CE ++ + C+ C
Sbjct: 773 ACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDP 832
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASC 279
G + D M C C G AG C
Sbjct: 833 QGAVRDDCEQ-MTGLCSCKPGVAGPKC 858
Score = 31.9 bits (69), Expect = 2.6
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCE 126
C NG SC C+CP G++G +CE
Sbjct: 1807 CLNGASCVPREAAYVCLCPGGFSGPHCE 1834
Score = 30.3 bits (65), Expect = 7.9
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC G C+ + + H C CP G G +C
Sbjct: 1532 HPCLPNPCHGGAPCQ-NLEAGRFH-CQCPPGRVGPTC 1566
>AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein.
Length = 2045
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/192 (30%), Positives = 86/192 (44%), Gaps = 6/192 (3%)
Frame = +1
Query: 151 SPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSV-GFNGNG 327
+P P PC PC +GGTC+ D TC CP G GA C+ LG V F G
Sbjct: 1325 APQQPPKPCDSQPCFHGGTCQ-DWALGGGFTCSCPAGRGGAVCEK--VLGAPVPAFEGRS 1381
Query: 328 YVELPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
++ P +L Y L +AL G+L Y + D+ L + G V
Sbjct: 1382 FLAFP-TLRAYHTLR-----LALEFRALEPQGLLLYNGNARGK----DFLALALLDGRVQ 1431
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGIS----NVM 672
L +D G G + + VP+ G+ H++ H LSVDG P G S + +
Sbjct: 1432 LRFDTGSGPAVLTSAVPVEPGQWHRLELSRHW-RRGTLSVDG---ETPVLGESPSGTDGL 1487
Query: 673 NADSNIYIGGIP 708
N D+++++GG+P
Sbjct: 1488 NLDTDLFVGGVP 1499
Score = 62.5 bits (145), Expect = 2e-09
Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 15/215 (6%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL---ELG--QSVGFNGNG 327
P S HPC NG +C P +++ C CP G++G C+ L G ++ F+G
Sbjct: 1817 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 1873
Query: 328 YVELPASLLRYDE-LASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
+VE ++ ++ L SN ++L T VL G+A DY L I G +
Sbjct: 1874 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVL---WSGKA-TERADYVALAIVDGHLQ 1929
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNV----M 672
L ++LG + VP+N +V A E L V AP TG S + +
Sbjct: 1930 LSYNLGSQPVVLRSTVPVNTNRWLRVVAH-REQREGSLQ---VGNEAPVTGSSPLGATQL 1985
Query: 673 NADSNIYIGGIPSWLNIHGYP-----GFIGCIENV 762
+ D +++GG+P P GF+GC+ +V
Sbjct: 1986 DTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDV 2020
Score = 60.9 bits (141), Expect = 5e-09
Identities = 57/231 (24%), Positives = 86/231 (37%), Gaps = 9/231 (3%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-- 213
C G C +C CPPG G C +PC +PC C+
Sbjct: 1558 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-----------KSPCQPNPCHGAAPCRVL 1606
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS----VGFNGNGYVELPASLLRYDELASNP 381
P+ + C+CPLG G CQ S FNG ++EL +L
Sbjct: 1607 PEGGA----QCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKM 1662
Query: 382 AVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPIN 561
A+ + + G+L Y GQ +GD+ L + + +DLG G + I P+
Sbjct: 1663 ALEVVFLARGPSGLLLY--NGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVT 1720
Query: 562 DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
G +V+ + A DG + V+N +Y+GG P +
Sbjct: 1721 LGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDF 1771
Score = 34.3 bits (75), Expect = 0.49
Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 7/87 (8%)
Frame = +1
Query: 40 SCQCEN----GGSCSTESTNCICPPGYTG---SYCETRIASYLMSPPPPVNPCSLHPCRN 198
+CQC GG+C + C C PG G CE ++ + C+ C
Sbjct: 792 ACQCNPHGSYGGTCDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDP 851
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASC 279
G + D M C C G AG C
Sbjct: 852 QGAVRDDCEQ-MTGLCSCKPGVAGPKC 877
Score = 31.9 bits (69), Expect = 2.6
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCE 126
C NG SC C+CP G++G +CE
Sbjct: 1826 CLNGASCVPREAAYVCLCPGGFSGPHCE 1853
Score = 30.3 bits (65), Expect = 7.9
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC G C+ + + H C CP G G +C
Sbjct: 1551 HPCLPNPCHGGAPCQ-NLEAGRFH-CQCPPGRVGPTC 1585
>BC106950-1|AAI06951.1| 685|Homo sapiens delta-like 4 (Drosophila)
protein.
Length = 685
Score = 71.3 bits (167), Expect = 3e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 63.7 bits (148), Expect = 7e-10
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 220 RNSWMNHTCDCPLGYAGASCQ-MPLELGQSVGFNG 321
+ + H C CP GY G C+ L S FNG
Sbjct: 343 EDGY--H-CLCPPGYYGLHCEHSTLSCADSPCFNG 374
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 57.2 bits (132), Expect = 6e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATC--SNSGQRS 307
Query: 238 HTCDCPLGYAGASCQMPL 291
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AY358894-1|AAQ89253.1| 685|Homo sapiens DLL4 protein.
Length = 685
Score = 71.3 bits (167), Expect = 3e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 63.7 bits (148), Expect = 7e-10
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 220 RNSWMNHTCDCPLGYAGASCQ-MPLELGQSVGFNG 321
+ + H C CP GY G C+ L S FNG
Sbjct: 343 EDGY--H-CLCPPGYYGLHCEHSTLSCADSPCFNG 374
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 57.2 bits (132), Expect = 6e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATC--SNSGQRS 307
Query: 238 HTCDCPLGYAGASCQMPL 291
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AF279305-1|AAF81912.1| 653|Homo sapiens delta 4 protein.
Length = 653
Score = 71.3 bits (167), Expect = 3e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 292 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 340
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 341 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 372
Score = 63.7 bits (148), Expect = 7e-10
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 262 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 310
Query: 220 RNSWMNHTCDCPLGYAGASCQ-MPLELGQSVGFNG 321
+ + H C CP GY G C+ L S FNG
Sbjct: 311 EDGY--H-CLCPPGYYGLHCEHSTLSCADSPCFNG 342
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 379 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 427
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N M C CP G++G C++
Sbjct: 428 NGLM---CTCPAGFSGRRCEV 445
Score = 57.2 bits (132), Expect = 6e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 417 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 467
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++ C+CP G+ G+ C+ P+ L S
Sbjct: 468 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 494
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 339 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 385
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
N + C C G+ G C++
Sbjct: 386 -LNRGPSRMCRCRPGFTGTYCEL 407
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 230 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATC--SNSGQRS 275
Query: 238 HTCDCPLGYAGASCQMPL 291
+TC C GY G C++ L
Sbjct: 276 YTCTCRPGYTGVDCELEL 293
>AF253468-1|AAF76427.1| 685|Homo sapiens notch ligand DLL4 protein.
Length = 685
Score = 71.3 bits (167), Expect = 3e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 63.7 bits (148), Expect = 7e-10
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 220 RNSWMNHTCDCPLGYAGASCQ-MPLELGQSVGFNG 321
+ + H C CP GY G C+ L S FNG
Sbjct: 343 EDGY--H-CLCPPGYYGLHCEHSTLSCADSPCFNG 374
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 57.2 bits (132), Expect = 6e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATC--SNSGQRS 307
Query: 238 HTCDCPLGYAGASCQMPL 291
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AB043894-1|BAB18581.1| 685|Homo sapiens Delta-4 protein.
Length = 685
Score = 71.3 bits (167), Expect = 3e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 63.7 bits (148), Expect = 7e-10
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 220 RNSWMNHTCDCPLGYAGASCQ-MPLELGQSVGFNG 321
+ + H C CP GY G C+ L S FNG
Sbjct: 343 EDGY--H-CLCPPGYYGLHCEHSTLSCADSPCFNG 374
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 57.2 bits (132), Expect = 6e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATC--SNSGQRS 307
Query: 238 HTCDCPLGYAGASCQMPL 291
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>AB036931-1|BAB16085.1| 685|Homo sapiens notch ligand delta-2
protein.
Length = 685
Score = 71.3 bits (167), Expect = 3e-12
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ +S C NGGSC + +C+CPPGY G +CE S C+ PC
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS-----------CADSPCF 372
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C+ +RN N+ C+CP + G++C+ ++
Sbjct: 373 NGGSCR-ERNQGANYACECPPNFTGSNCEKKVD 404
Score = 63.7 bits (148), Expect = 7e-10
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +CS S C C PGYTG CE ++ C +PCRNGG+CK
Sbjct: 294 CKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE-----------CDSNPCRNGGSCKDQ 342
Query: 220 RNSWMNHTCDCPLGYAGASCQ-MPLELGQSVGFNG 321
+ + H C CP GY G C+ L S FNG
Sbjct: 343 EDGY--H-CLCPPGYYGLHCEHSTLSCADSPCFNG 374
Score = 61.7 bits (143), Expect = 3e-09
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C S C C PG+TG+YCE V+ C+ +PC +GGTC
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELH-----------VSDCARNPCAHGGTCHDLE 459
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N M C CP G++G C++
Sbjct: 460 NGLM---CTCPAGFSGRRCEV 477
Score = 57.2 bits (132), Expect = 6e-08
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C CP G++G CE R + ++ C+ PC N TC D
Sbjct: 449 CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTS---------IDACASSPCFNRATCYTDL 499
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++ C+CP G+ G+ C+ P+ L S
Sbjct: 500 ST-DTFVCNCPYGFVGSRCEFPVGLPPS 526
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGGSC + C CPP +TGS CE + V+ C+ +PC NGG C
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKK-----------VDRCTSNPCANGGQC-- 417
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
N + C C G+ G C++
Sbjct: 418 -LNRGPSRMCRCRPGFTGTYCEL 439
Score = 48.0 bits (109), Expect = 4e-05
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+CST C C G+ G +C+ + N C+ H PC+NG TC + +
Sbjct: 262 GTCSTP-WQCTCDEGWGGLFCDQDL-----------NYCTHHSPCKNGATC--SNSGQRS 307
Query: 238 HTCDCPLGYAGASCQMPL 291
+TC C GY G C++ L
Sbjct: 308 YTCTCRPGYTGVDCELEL 325
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 611 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 659
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 660 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 689
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 444 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 492
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 493 INRFQ---CLCPTGFSGNLCQLDID 514
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 728 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 776
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 777 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 813
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 474 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 522
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 523 NGAQC---YNRASDYFCKCPEDYEGKNC 547
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 586 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 634
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 635 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 666
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 686 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 734
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 735 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 766
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 293 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 339
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 340 -ETSLGFECECSPGWTGPTCSTNID 363
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 332 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 380
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 381 NGF---KCVCPPQWTGKTCQL 398
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 370 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 415
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 416 NLIASYYCDCLPGWMGQNCDININDCLGQ 444
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 778 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 826
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 827 NGYR---CVCPPGHSGAKCQ 843
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 261 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 306
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 307 ---YQCSCPEGYSGPNCEI 322
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 663 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 711
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 712 DAF---KCMCPGGWEGTTCNI 729
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 512 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 571
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 572 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 613
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 805 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 849
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 850 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 880
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 70.5 bits (165), Expect = 6e-12
Identities = 35/80 (43%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S C+CPPG+TGSYC+ VN C PC GGTC+ R
Sbjct: 993 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HVVNECDSRPCLLGGTCQDGR 1041
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
H C CP GY G +CQ
Sbjct: 1042 GL---HRCTCPQGYTGPNCQ 1058
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 908 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 955
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
RNG C +S +TC CP G++G C+ + +S FNG V+
Sbjct: 956 RNGANCTDCVDS---YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1001
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 941 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 989
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 990 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1020
Score = 56.4 bits (130), Expect = 1e-07
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQ 303
S++ C CP + G +C+ + E GQ
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQ 184
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +1
Query: 37 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNI-----------NECASNPCLNKGTC 806
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPL 291
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PCR GTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRLRGTCQDPDNAYL---CFCLKGTTGPNCEINLD 643
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-PD 219
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
GTC D + + C CP G++G SCQ + NG + AS +
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYI 163
Score = 54.4 bits (125), Expect = 4e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C++G +C + C C PGYTGS C + I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNSNI-----------DECAGNPCHNGGTCE 694
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 216
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCPCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + + +S C GG+C C CP GYTG C+ V+ C
Sbjct: 1017 SYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNL-----------VHWCD 1065
Query: 181 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 288
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1066 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1098
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1117 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1162
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G +C ++
Sbjct: 1163 DYLGGYSCKCVAGYHGVNCSEEID 1186
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1267 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1315
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1316 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1347
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPP-GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C ES +C+CP G G CE I N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDI-----------NECVLSPCRHGASC- 885
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+N+ + C C GY+G +C+ ++
Sbjct: 886 --QNTHGXYRCHCQAGYSGRNCETDID 910
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R +I +E S C+N +C + C+C PGY G +CE
Sbjct: 443 GYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVN-----------T 491
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C+ PC + G C N + C+CP G+ G CQ ++
Sbjct: 492 DECASSPCLHNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1155 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1203
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N+ + C CP G G C++ ++
Sbjct: 1204 NT---YKCSCPRGTQGVHCEINVD 1224
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.6 bits (108), Expect = 5e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 870 DINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 918
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N+ CDC G+ G C+
Sbjct: 919 NGGSCTDGINTAF---CDCLPGFRGTFCE 944
Score = 47.2 bits (107), Expect = 6e-05
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G +R + S S C+NGG+C C C PG+TG CE I +
Sbjct: 212 GPNCERPYVPCSPS-PCQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------D 259
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C + C+NGG C N+ + C CP + G C
Sbjct: 260 DCPGNNCKNGGACVDGVNT---YNCPCPPEWTGQYC 292
Score = 47.2 bits (107), Expect = 6e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 192
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1349 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1398
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
N GTC+P S + C CP + G C +
Sbjct: 1399 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1428
Score = 46.8 bits (106), Expect = 9e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQMPL 291
NGG C+ + + + +C CP G G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTAGAKGQTCEVDI 871
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C S C C PG++G+ C+ N C +PC NGGTCK D S +
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTSGI 775
Query: 235 NHTCDCPLGYAGASCQ 282
C C G++G +CQ
Sbjct: 776 --VCTCREGFSGPNCQ 789
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 210
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 5e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C C GY G C++
Sbjct: 472 GEFQ---CMCMPGYEGVHCEV 489
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 34 SESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S S +C N G+C + +C CPPG+ G CE VN C +PC GT
Sbjct: 1234 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------GDVNECLSNPCDARGT 1282
Query: 208 --CKPDRNSWMNHTCDCPLGYAGASCQ 282
C N + H C+C G+ G C+
Sbjct: 1283 QNCVQRVNDF--H-CECRAGHTGRRCE 1306
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +1
Query: 40 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 294
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 32.3 bits (70), Expect = 2.0
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C G+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ GTC + + C C GY G+ C ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNSNID 680
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 34.7 bits (76), Expect = 0.37
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
R +I +S C G +C E C+CPPG++G+ C+
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ 856
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 70.5 bits (165), Expect = 6e-12
Identities = 35/80 (43%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S C+CPPG+TGSYC+ VN C PC GGTC+ R
Sbjct: 993 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HVVNECDSRPCLLGGTCQDGR 1041
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
H C CP GY G +CQ
Sbjct: 1042 GL---HRCTCPQGYTGPNCQ 1058
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 908 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 955
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
RNG C +S +TC CP G++G C+ + +S FNG V+
Sbjct: 956 RNGANCTDCVDS---YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1001
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 941 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 989
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 990 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1020
Score = 56.4 bits (130), Expect = 1e-07
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQ 303
S++ C CP + G +C+ + E GQ
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQ 184
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +1
Query: 37 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGIVCTCREGFSGPNCQTNI-----------NECASNPCLNKGTC 806
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPL 291
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PCR GTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRLRGTCQDPDNAYL---CFCLKGTTGPNCEINLD 643
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-PD 219
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
GTC D + + C CP G++G SCQ + NG + AS +
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYI 163
Score = 54.4 bits (125), Expect = 4e-07
Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C++G +C + C C PGYTGS C + I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNSNI-----------DECAGNPCHNGGTCE 694
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 216
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCPCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + + +S C GG+C C CP GYTG C+ V+ C
Sbjct: 1017 SYCQHVVNECDSRPCLLGGTCQDGRGLHRCTCPQGYTGPNCQNL-----------VHWCD 1065
Query: 181 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 288
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1066 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1098
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1117 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1162
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G +C ++
Sbjct: 1163 DYLGGYSCKCVAGYHGVNCSEEID 1186
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1267 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1315
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1316 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1347
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPP-GYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C ES +C+CP G G CE I N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTAGAKGQTCEVDI-----------NECVLSPCRHGASC- 885
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+N+ + C C GY+G +C+ ++
Sbjct: 886 --QNTHGXYRCHCQAGYSGRNCETDID 910
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R +I +E S C+N +C + C+C PGY G +CE
Sbjct: 443 GYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCMCMPGYEGVHCEVN-----------T 491
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C+ PC + G C N + C+CP G+ G CQ ++
Sbjct: 492 DECASSPCLHNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1155 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1203
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N+ + C CP G G C++ ++
Sbjct: 1204 NT---YKCSCPRGTQGVHCEINVD 1224
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.6 bits (108), Expect = 5e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 870 DINECVLSPCRHGASCQNTHGXYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 918
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N+ CDC G+ G C+
Sbjct: 919 NGGSCTDGINTAF---CDCLPGFRGTFCE 944
Score = 47.2 bits (107), Expect = 6e-05
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G +R + S S C+NGG+C C C PG+TG CE I +
Sbjct: 212 GPNCERPYVPCSPS-PCQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------D 259
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C + C+NGG C N+ + C CP + G C
Sbjct: 260 DCPGNNCKNGGACVDGVNT---YNCPCPPEWTGQYC 292
Score = 47.2 bits (107), Expect = 6e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 192
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1349 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1398
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
N GTC+P S + C CP + G C +
Sbjct: 1399 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1428
Score = 46.8 bits (106), Expect = 9e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNKGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQMPL 291
NGG C+ + + + +C CP G G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTAGAKGQTCEVDI 871
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C S C C PG++G+ C+ N C +PC NGGTCK D S +
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTSGI 775
Query: 235 NHTCDCPLGYAGASCQ 282
C C G++G +CQ
Sbjct: 776 --VCTCREGFSGPNCQ 789
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 210
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 5e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C C GY G C++
Sbjct: 472 GEFQ---CMCMPGYEGVHCEV 489
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 34 SESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S S +C N G+C + +C CPPG+ G CE VN C +PC GT
Sbjct: 1234 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------GDVNECLSNPCDARGT 1282
Query: 208 --CKPDRNSWMNHTCDCPLGYAGASCQ 282
C N + H C+C G+ G C+
Sbjct: 1283 QNCVQRVNDF--H-CECRAGHTGRRCE 1306
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +1
Query: 40 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 294
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 32.3 bits (70), Expect = 2.0
Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C G+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRLRGTCQDPDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ GTC + + C C GY G+ C ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNSNID 680
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 63.3 bits (147), Expect = 9e-10
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC NGG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLNGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C E C+CP G++G+ C+ ++ C +PC+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQL-----------DIDYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/93 (40%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I ES C NGG+C S CIC G+ G+YCET I N CS
Sbjct: 624 TYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-----------NDCS 672
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC NGGTC+ N + CDC G+ G +C
Sbjct: 673 QNPCHNGGTCRDLVNDFY---CDCKNGWKGKTC 702
Score = 61.3 bits (142), Expect = 4e-09
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC+N SC CICPPGY G +CE ++ C+ +PC +GG C+ +
Sbjct: 457 QCQNDASCRDLVNGYRCICPPGYAGDHCER-----------DIDECASNPCLDGGHCQNE 505
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G++G CQ+ ++
Sbjct: 506 INRFQ---CLCPTGFSGNLCQLDID 527
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 22 DIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I + SC C NGG+C + ES C+C G+ G C N CS H
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPH 789
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
PC N GTC D ++W + C+C G+AG C++ + QS
Sbjct: 790 PCYNSGTC-VDGDNW--YRCECAPGFAGPDCRININECQS 826
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++S C C G+TG+YC I N C +PCRNGGTC
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI-----------NDCESNPCRNGGTCIDG 647
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
NS + C C G+ GA C+ + + Q+ NG
Sbjct: 648 VNS---YKCICSDGWEGAYCETNINDCSQNPCHNG 679
Score = 51.6 bits (118), Expect = 3e-06
Identities = 34/95 (35%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T D Q E+ C NGG+C E + C+CP G+ G+ C IA +
Sbjct: 699 GKTCHSRDSQCDEAT-CNNGGTCYDEGDAFKCMCPGGWEGTTC--NIARN--------SS 747
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 748 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 779
Score = 50.4 bits (115), Expect = 7e-06
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +GG C E C+CP G++G+ C+ I + C +PC+
Sbjct: 487 DIDECASNPCLDGGHCQNEINRFQCLCPTGFSGNLCQLDI-----------DYCEPNPCQ 535
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NG C N ++ C CP Y G +C
Sbjct: 536 NGAQC---YNRASDYFCKCPEDYEGKNC 560
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+CS + C CP GY+G CE IA + C PC N G+CK
Sbjct: 306 CLNGGTCSNTGPDKYQCSCPEGYSGPNCE--IAEH---------ACLSDPCHNRGSCK-- 352
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C G+ G +C ++
Sbjct: 353 -ETSLGFECECSPGWTGPTCSTNID 376
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N GSC S C C PG+TG C T I + CS + C +GGTC+
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNI-----------DDCSPNNCSHGGTCQDLV 393
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C CP + G +CQ+
Sbjct: 394 NGF---KCVCPPQWTGKTCQL 411
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C C+CPP +TG C+ N C PC N +CK
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQL-----------DANECEAKPCVNAKSCK--- 428
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE--LGQ 303
N ++ CDC G+ G +C + + LGQ
Sbjct: 429 NLIASYYCDCLPGWMGQNCDININDCLGQ 457
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 791 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 839
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 840 NGYR---CVCPPGHSGAKCQ 856
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK---PDRNS 228
G C+ E C+C + G C+ + N C H PC NGGTC PD+
Sbjct: 274 GICN-EPWQCLCETNWGGQLCDKDL-----------NYCGTHQPCLNGGTCSNTGPDK-- 319
Query: 229 WMNHTCDCPLGYAGASCQM 285
+ C CP GY+G +C++
Sbjct: 320 ---YQCSCPEGYSGPNCEI 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C C C G+ G C +R + C C NGGTC +
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQ-----------CDEATCNNGGTCYDEG 724
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+++ C CP G+ G +C +
Sbjct: 725 DAF---KCMCPGGWEGTTCNI 742
Score = 36.7 bits (81), Expect = 0.091
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 18/104 (17%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTG-------SYCET---------RIASYL 147
DI E C+NG C +++ C CP Y G +C T +A
Sbjct: 525 DIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 148 MSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
P V S + C G CK S TCDC G+ G C
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCK--SQSGGKFTCDCNKGFTGTYC 626
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 818 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 862
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 863 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 893
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 69.7 bits (163), Expect = 1e-11
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 210
+ CQC+NG +C + C CPPGYTG++CE + PP P C PC+NGG C
Sbjct: 193 QRCQCQNGATCDHVTGECRCPPGYTGAFCED------LCPPGKHGPQCEQRCPCQNGGVC 246
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
+ C CP G+ G C P G+
Sbjct: 247 -----HHVTGECSCPSGWMGTVCGQPCPEGR 272
Score = 55.2 bits (127), Expect = 2e-07
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S+ CQC NGG+C + C C PGYTG C E + +Y V C NGG
Sbjct: 278 SQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTY------GVLCAETCQCVNGGK 331
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C ++ C C G+AG C+ L
Sbjct: 332 C-----YHVSGACLCEAGFAGERCEARL 354
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 10/96 (10%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLM--------SPPPPVNPCS 180
+ +E+CQC NGG C S C+C G+ G CE R+ + P N S
Sbjct: 318 VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
Query: 181 LHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQ 282
HP CKP W C+ C G+ G +CQ
Sbjct: 378 CHPMSGECACKP---GWSGLYCNETCSPGFYGEACQ 410
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 1/92 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 204
Q + C C+NGG C + C CP G+ G+ C CS C NGG
Sbjct: 233 QCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG-----KNCSQECQCHNGG 287
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
TC C C GY G CQ +G
Sbjct: 288 TCDAATGQ-----CHCSPGYTGERCQDECPVG 314
Score = 50.4 bits (115), Expect = 7e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
CQC+NG C+ + C C G+ G CE R N C C+NG TC
Sbjct: 152 CQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYG-----NDCHQRCQCQNGATC--- 203
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ C CP GY GA C+
Sbjct: 204 --DHVTGECRCPPGYTGAFCE 222
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
I S C C+N CS +C C G+ G C R S C+L C NG
Sbjct: 450 INCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG-----FGCNLTCQCLNG 504
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
G C + ++ TC C G+ G C++P + G + G N
Sbjct: 505 GAC-----NTLDGTCTCAPGWRGEKCELPCQDG-TYGLN 537
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCET--RIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C C+NG C + + C C PG+ G C T + +Y +N S C+N C P
Sbjct: 413 CSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY------GINCSSRCGCKNDAVCSP 466
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C + G + GF N
Sbjct: 467 -----VDGSCTCKAGWHGVDCSIRCPSG-TWGFGCN 496
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/80 (28%), Positives = 32/80 (40%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNH 240
G C +T C C PG+ G+ C + P + S C+NG C P +
Sbjct: 116 GRCIAPNT-CQCEPGWGGTNCSSACDGDHWGP----HCTSRCQCKNGALCNP-----ITG 165
Query: 241 TCDCPLGYAGASCQMPLELG 300
C C G+ G C+ E G
Sbjct: 166 ACHCAAGFRGWRCEDRCEQG 185
Score = 30.7 bits (66), Expect = 6.0
Identities = 9/32 (28%), Positives = 17/32 (53%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSY 120
+ +E C C + C + +C C PG++G +
Sbjct: 536 LNCAERCDCSHADGCHPTTGHCRCLPGWSGLF 567
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 69.7 bits (163), Expect = 1e-11
Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 210
+ CQC+NG +C + C CPPGYTG++CE + PP P C PC+NGG C
Sbjct: 193 QRCQCQNGATCDHVTGECRCPPGYTGAFCED------LCPPGKHGPQCEQRCPCQNGGVC 246
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
+ C CP G+ G C P G+
Sbjct: 247 -----HHVTGECSCPSGWMGTVCGQPCPEGR 272
Score = 56.8 bits (131), Expect = 8e-08
Identities = 26/86 (30%), Positives = 43/86 (50%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ +E C C + C + +C C PG++G +C++ A P + PC C+NG
Sbjct: 536 LNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSL-PCY---CKNGA 591
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
+C PD + C+C G+ G +CQ
Sbjct: 592 SCSPD-----DGICECAPGFRGTTCQ 612
Score = 55.2 bits (127), Expect = 2e-07
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S+ CQC NGG+C + C C PGYTG C E + +Y V C NGG
Sbjct: 278 SQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTY------GVLCAETCQCVNGGK 331
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C ++ C C G+AG C+ L
Sbjct: 332 C-----YHVSGACLCEAGFAGERCEARL 354
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 10/96 (10%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLM--------SPPPPVNPCS 180
+ +E+CQC NGG C S C+C G+ G CE R+ + P N S
Sbjct: 318 VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
Query: 181 LHPCRNGGTCKPDRNSWMNHTCD--CPLGYAGASCQ 282
HP CKP W C+ C G+ G +CQ
Sbjct: 378 CHPMSGECACKP---GWSGLYCNETCSPGFYGEACQ 410
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 1/92 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 204
Q + C C+NGG C + C CP G+ G+ C CS C NGG
Sbjct: 233 QCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG-----KNCSQECQCHNGG 287
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
TC C C GY G CQ +G
Sbjct: 288 TCDAATGQ-----CHCSPGYTGERCQDECPVG 314
Score = 50.4 bits (115), Expect = 7e-06
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 1/81 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
CQC+NG C+ + C C G+ G CE R N C C+NG TC
Sbjct: 152 CQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYG-----NDCHQRCQCQNGATC--- 203
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ C CP GY GA C+
Sbjct: 204 --DHVTGECRCPPGYTGAFCE 222
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNG 201
I S C C+N CS +C C G+ G C R S C+L C NG
Sbjct: 450 INCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG-----FGCNLTCQCLNG 504
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
G C + ++ TC C G+ G C++P + G + G N
Sbjct: 505 GAC-----NTLDGTCTCAPGWRGEKCELPCQDG-TYGLN 537
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCET--RIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C C+NG C + + C C PG+ G C T + +Y +N S C+N C P
Sbjct: 413 CSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY------GINCSSRCGCKNDAVCSP 466
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ +C C G+ G C + G + GF N
Sbjct: 467 -----VDGSCTCKAGWHGVDCSIRCPSG-TWGFGCN 496
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKP 216
+C C NG CS C C PG+TG YC R C+L C+NG C
Sbjct: 715 TCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG-----KDCALICQCQNGADC-- 767
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELG 300
++ C C G+ G C+ G
Sbjct: 768 ---DHISGQCTCRTGFMGRHCEQKCPSG 792
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCE--TRIASYLMSPPPPVNPCS----LHPCRNG 201
+CQC NGG+C+T C C PG+ G CE + +Y ++ + CS HP
Sbjct: 498 TCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCD-CSHADGCHPTTGH 556
Query: 202 GTCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
C P W CD C G G +C +P
Sbjct: 557 CRCLP---GWSGVHCDSVCAEGRWGPNCSLP 584
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 28 QASESC-QC-ENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ S++C QC + G C + C C PG+TG+ C S N + C N
Sbjct: 623 RCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGK----NCAGICTCTNN 678
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
GTC P ++ +C C G+ G+ C P
Sbjct: 679 GTCNP-----IDRSCQCYPGWIGSDCSQP 702
Score = 46.0 bits (104), Expect = 1e-04
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 216
C C N G+C+ +C C PG+ GS C PP P +H C NG C
Sbjct: 673 CTCTNNGTCNPIDRSCQCYPGWIGSDCSQ------PCPPAHWGPNCIHTCNCHNGAFC-- 724
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELG 300
S + C C G+ G C LG
Sbjct: 725 ---SAYDGECKCTPGWTGLYCTQRCPLG 749
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/79 (31%), Positives = 32/79 (40%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CQC+NG C S C C G+ G +CE + S + C N TC
Sbjct: 759 CQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG----YGCRQICDCLNNSTC---- 810
Query: 223 NSWMNHTCDCPLGYAGASC 279
+ TC C G+ GA C
Sbjct: 811 -DHITGTCYCSPGWKGARC 828
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/79 (32%), Positives = 34/79 (43%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+NG SCS + C C PG+ G+ C+ RI S C + G C
Sbjct: 585 CYCKNGASCSPDDGICECAPGFRGTTCQ-RICSPGFYGHRCSQTCP-QCVHSSGPC---- 638
Query: 223 NSWMNHTCDCPLGYAGASC 279
+ CDC G+ GA C
Sbjct: 639 -HHITGLCDCLPGFTGALC 656
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/80 (28%), Positives = 32/80 (40%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNH 240
G C +T C C PG+ G+ C + P + S C+NG C P +
Sbjct: 116 GRCIAPNT-CQCEPGWGGTNCSSACDGDHWGP----HCTSRCQCKNGALCNP-----ITG 165
Query: 241 TCDCPLGYAGASCQMPLELG 300
C C G+ G C+ E G
Sbjct: 166 ACHCAAGFRGWRCEDRCEQG 185
Score = 32.7 bits (71), Expect = 1.5
Identities = 10/28 (35%), Positives = 15/28 (53%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
C C N +C + C C PG+ G+ C+
Sbjct: 802 CDCLNNSTCDHITGTCYCSPGWKGARCD 829
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 69.3 bits (162), Expect = 1e-11
Identities = 34/80 (42%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S C+CPPG+TGSYC+ VN C PC +GGTC+
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HDVNECDSQPCLHGGTCQDGC 1040
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
S + C CP GY G +CQ
Sbjct: 1041 GS---YRCTCPQGYTGPNCQ 1057
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 907 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 954
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
RNG C +S +TC CP G++G C+ + +S FNG V+
Sbjct: 955 RNGANCTDCVDS---YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + D+ +S C +GG+C S C CP GYTG C+ V+ C
Sbjct: 1016 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL-----------VHWCD 1064
Query: 181 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 288
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1065 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1097
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PCR+GGTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRHGGTCQDRDNAYL---CFCLKGTTGPNCEINLD 643
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGG C ES +C+CP G+ G CE +N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGASC-- 884
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+N+ + C C GY+G +C+ ++
Sbjct: 885 -QNTHGGYRCHCQAGYSGRNCETDID 909
Score = 58.8 bits (136), Expect = 2e-08
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNG 327
S++ C CP + G +C+ + E GQ G +G
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQKPGLCRHG 192
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 940 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 988
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 989 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1019
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +1
Query: 37 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-----------NECASNPCLNQGTC 806
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPL 291
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-PD 219
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
GTC D + + C CP G++G SCQ + NG + AS +
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYI 163
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 216
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1161
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G +C ++
Sbjct: 1162 DYLGGYSCKCVAGYHGVNCSEEID 1185
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1266 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1314
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C++G +C + C C PGYTGS C I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNINI-----------DECAGNPCHNGGTCE 694
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NGG C+ + + + +C CP G+ G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTGWQGQTCEVDI 870
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R +I +E S C+N +C + CIC PGY G +CE
Sbjct: 443 GYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN-----------T 491
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C+ PC + G C N + C+CP G+ G CQ ++
Sbjct: 492 DECASSPCLHNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1202
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N+ + C CP G G C++ ++
Sbjct: 1203 NT---YKCSCPRGTQGVHCEINVD 1223
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 869 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 917
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N+ CDC G+ G C+
Sbjct: 918 NGGSCTDGINTAF---CDCLPGFRGTFCE 943
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C S C C PG++G+ C+ N C +PC NGGTCK D S
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTS-- 773
Query: 235 NHTCDCPLGYAGASCQ 282
+ C C G++G +CQ
Sbjct: 774 GYVCTCREGFSGPNCQ 789
Score = 47.2 bits (107), Expect = 6e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 192
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1397
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
N GTC+P S + C CP + G C +
Sbjct: 1398 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1427
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G +R + S S C+NGG+C C C PG+TG CE I +
Sbjct: 212 GPNCERPYVPCSPS-PCQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------D 259
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C + C+NGG C N+ + C CP + G C
Sbjct: 260 DCPGNNCKNGGACVDGVNT---YNCRCPPEWTGQYC 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 210
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 5e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C C GY G C++
Sbjct: 472 GEFQ---CICMPGYEGVHCEV 489
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 34 SESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S S +C N G+C + +C CPPG+ G CE VN C +PC GT
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------GDVNECLSNPCDARGT 1281
Query: 208 --CKPDRNSWMNHTCDCPLGYAGASCQ 282
C N + H C+C G+ G C+
Sbjct: 1282 QNCVQRVNDF--H-CECRAGHTGRRCE 1305
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +1
Query: 40 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 294
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 38.3 bits (85), Expect = 0.030
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C +GG+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ GTC + + C C GY G+ C + ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNINID 680
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 69.3 bits (162), Expect = 1e-11
Identities = 34/80 (42%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S C+CPPG+TGSYC+ VN C PC +GGTC+
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HDVNECDSQPCLHGGTCQDGC 1040
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
S + C CP GY G +CQ
Sbjct: 1041 GS---YRCTCPQGYTGPNCQ 1057
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 907 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 954
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
RNG C +S +TC CP G++G C+ + +S FNG V+
Sbjct: 955 RNGANCTDCVDS---YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + D+ +S C +GG+C S C CP GYTG C+ V+ C
Sbjct: 1016 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL-----------VHWCD 1064
Query: 181 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 288
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 1065 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 1097
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 609
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PCR+GGTC+ N+++ C C G G +C++ L+
Sbjct: 610 QPCRHGGTCQDRDNAYL---CFCLKGTTGPNCEINLD 643
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/80 (37%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C E S C+C +TG CE P PCS PC+NGGTC+P
Sbjct: 189 CRHGGTCHNEVGSYRCVCRATHTGPNCER-----------PYVPCSPSPCQNGGTCRPTG 237
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + H C C G+ G +C+
Sbjct: 238 D--VTHECACLPGFTGQNCE 255
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGG C ES +C+CP G+ G CE +N C L PCR+G +C
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGASC-- 884
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+N+ + C C GY+G +C+ ++
Sbjct: 885 -QNTHGGYRCHCQAGYSGRNCETDID 909
Score = 58.8 bits (136), Expect = 2e-08
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CPPG++G C+ +PC+ +PC NGG C P
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ------------ADPCASNPCANGGQCLPF 158
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNG 327
S++ C CP + G +C+ + E GQ G +G
Sbjct: 159 EASYI---CHCPPSFHGPTCRQDVNECGQKPGLCRHG 192
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 940 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 988
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 989 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 1019
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +1
Query: 37 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 758 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-----------NECASNPCLNQGTC 806
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPL 291
D + C+C L Y GA+C++ L
Sbjct: 807 IDD---VAGYKCNCLLPYTGATCEVVL 830
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-PD 219
C NGG C + C+C + G C+ P NPC PC+N GTC D
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ--------DP----NPCLSTPCKNAGTCHVVD 78
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
R ++ C C LG++G C PL+
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLD 103
Score = 54.4 bits (125), Expect = 4e-07
Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 6/111 (5%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
S C+N G+C C C G++G C T P N C +PCRNG
Sbjct: 65 STPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----------PLDNACLTNPCRNG 114
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
GTC D + + C CP G++G SCQ + NG + AS +
Sbjct: 115 GTC--DLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYI 163
Score = 54.0 bits (124), Expect = 6e-07
Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCKP 216
C+NGG+C + NC CPP +TG YC V+ C L P C+NGGTC
Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYC-----------TEDVDECQLMPNACQNGGTC-- 312
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N+ + C C G+ G C
Sbjct: 313 -HNTHGGYNCVCVNGWTGEDC 332
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 1161
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G +C ++
Sbjct: 1162 DYLGGYSCKCVAGYHGVNCSEEID 1185
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 1266 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 1314
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 1346
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C++G +C + C C PGYTGS C I + C+ +PC NGGTC+
Sbjct: 647 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNINI-----------DECAGNPCHNGGTCE 694
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
N + TC CP GY +C
Sbjct: 695 DGINGF---TCRCPEGYHDPTC 713
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 791 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 839
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NGG C+ + + + +C CP G+ G +C++ +
Sbjct: 840 NGGECRQSED-YESFSCVCPTGWQGQTCEVDI 870
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R +I +E S C+N +C + CIC PGY G +CE
Sbjct: 443 GYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVN-----------T 491
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C+ PC + G C N + C+CP G+ G CQ ++
Sbjct: 492 DECASSPCLHNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 530
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 1202
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N+ + C CP G G C++ ++
Sbjct: 1203 NT---YKCSCPRGTQGVHCEINVD 1223
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 869 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 917
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N+ CDC G+ G C+
Sbjct: 918 NGGSCTDGINTAF---CDCLPGFRGTFCE 943
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 544
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N+ +TC C GY G C++ ++
Sbjct: 545 DGPNT---YTCVCTEGYTGTHCEVDID 568
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C S C C PG++G+ C+ N C +PC NGGTCK D S
Sbjct: 728 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTS-- 773
Query: 235 NHTCDCPLGYAGASCQ 282
+ C C G++G +CQ
Sbjct: 774 GYVCTCREGFSGPNCQ 789
Score = 47.2 bits (107), Expect = 6e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 192
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 1348 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 1397
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
N GTC+P S + C CP + G C +
Sbjct: 1398 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 1427
Score = 46.8 bits (106), Expect = 9e-05
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G +R + S S C+NGG+C C C PG+TG CE I +
Sbjct: 212 GPNCERPYVPCSPS-PCQNGGTCRPTGDVTHECACLPGFTGQNCEENI-----------D 259
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C + C+NGG C N+ + C CP + G C
Sbjct: 260 DCPGNNCKNGGACVDGVNT---YNCRCPPEWTGQYC 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 528 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 575
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G+CK + TC C GY G C+
Sbjct: 576 HYGSCK---DGVATFTCLCRPGYTGHHCE 601
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 6/85 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTC 210
C G +C T N C CP GYTG C V+ CSL +PC + G C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACS-----------QDVDECSLGANPCEHAGKC 429
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
N+ + C C GY G C++
Sbjct: 430 ---INTLGSFECQCLQGYTGPRCEI 451
Score = 44.4 bits (100), Expect = 5e-04
Identities = 27/81 (33%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C + S C C GYTG CE VN C +PC+N TC
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEI-----------DVNECVSNPCQNDATCLDQI 471
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C C GY G C++
Sbjct: 472 GEFQ---CICMPGYEGVHCEV 489
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 34 SESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S S +C N G+C + +C CPPG+ G CE VN C +PC GT
Sbjct: 1233 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------GDVNECLSNPCDARGT 1281
Query: 208 --CKPDRNSWMNHTCDCPLGYAGASCQ 282
C N + H C+C G+ G C+
Sbjct: 1282 QNCVQRVNDF--H-CECRAGHTGRRCE 1305
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 12/97 (12%)
Frame = +1
Query: 40 SCQCENGGS---CSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
+C C NG + CS +C + G+ C R+AS+ P + C +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISN 379
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLE 294
PC G C D N C CP GY G +C ++
Sbjct: 380 PCNEGSNC--DTNPVNGKAICTCPSGYTGPACSQDVD 414
Score = 38.3 bits (85), Expect = 0.030
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C +GG+C C C G TG CE + + C+ PC
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 650
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ GTC + + C C GY G+ C + ++
Sbjct: 651 DSGTCLDKID---GYECACEPGYTGSMCNINID 680
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein
variant protein.
Length = 2067
Score = 69.3 bits (162), Expect = 1e-11
Identities = 34/80 (42%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S C+CPPG+TGSYC+ VN C PC +GGTC+
Sbjct: 504 CFNGGTCVDGINSFTCLCPPGFTGSYCQ-----------HDVNECDSQPCLHGGTCQDGC 552
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
S + C CP GY G +CQ
Sbjct: 553 GS---YRCTCPQGYTGPNCQ 569
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 52/109 (47%), Gaps = 4/109 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
DI C NGGSC T+ N C C PG+ G++CE +N C+ PC
Sbjct: 419 DIDDCRPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-----------EDINECASDPC 466
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
RNG C +S +TC CP G++G C+ + +S FNG V+
Sbjct: 467 RNGANCTDCVDS---YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 512
Score = 61.3 bits (142), Expect = 4e-09
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + D+ +S C +GG+C S C CP GYTG C+ V+ C
Sbjct: 528 SYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL-----------VHWCD 576
Query: 181 LHPCRNGGTCKPDRNSWMNHT---CDCPLGYAGASCQMP 288
PC+NGG C W HT C+CP G+ G C +P
Sbjct: 577 SSPCKNGGKC------WQTHTQYRCECPSGWTGLYCDVP 609
Score = 60.5 bits (140), Expect = 6e-09
Identities = 34/97 (35%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
T+ DI + C G +T C+C PGYTG +CET I N CS
Sbjct: 73 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNI-----------NECSS 121
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PCR+GGTC+ N+++ C C G G +C++ L+
Sbjct: 122 QPCRHGGTCQDRDNAYL---CFCLKGTTGPNCEINLD 155
Score = 59.7 bits (138), Expect = 1e-08
Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C NGG C ES +C+CP G+ G CE +N C L PCR+G +C
Sbjct: 350 CRNGGECRQSEDYESFSCVCPTGWQGQTCEV-----------DINECVLSPCRHGASC-- 396
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+N+ + C C GY+G +C+ ++
Sbjct: 397 -QNTHGGYRCHCQAGYSGRNCETDID 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ DI S C NG +C+ +S C CP G++G +CE +P C+
Sbjct: 452 TFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENN------TP-----DCT 500
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C NGGTC NS+ TC CP G+ G+ CQ
Sbjct: 501 ESSCFNGGTCVDGINSF---TCLCPPGFTGSYCQ 531
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
Frame = +1
Query: 37 ESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
ES C NGG+C T C C G++G C+T I N C+ +PC N GTC
Sbjct: 270 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI-----------NECASNPCLNQGTC 318
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPL 291
D + C+C L Y GA+C++ L
Sbjct: 319 IDD---VAGYKCNCLLPYTGATCEVVL 342
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + + +C C GYTGSYCE V+ CS PC+NG TC
Sbjct: 628 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDL-----------VDECSPSPCQNGATC---T 673
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G +C ++
Sbjct: 674 DYLGGYSCKCVAGYHGVNCSEEID 697
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGS--C--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ S C+ G+ C +C C G+TG CE+ I N C
Sbjct: 778 GDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVI-----------NGCKGK 826
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC+NGGTC N+ C CP G+ GA+C+
Sbjct: 827 PCKNGGTCAVASNTARGFICKCPAGFEGATCE 858
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C++G +C + C C PGYTGS C I + C+ +PC NGGTC+
Sbjct: 159 SSPCDSG-TCLDKIDGYECACEPGYTGSMCNINI-----------DECAGNPCHNGGTCE 206
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
N + TC CP GY +C
Sbjct: 207 DGINGF---TCRCPEGYHDPTC 225
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C C YTG+ CE +A PC+ PCR
Sbjct: 303 NINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLA-----------PCAPSPCR 351
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
NGG C+ + + + +C CP G+ G +C++ +
Sbjct: 352 NGGECRQSED-YESFSCVCPTGWQGQTCEVDI 382
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C+ +C C GY G C I + C HPC+NGGTC
Sbjct: 666 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI-----------DECLSHPCQNGGTCLDLP 714
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N+ + C CP G G C++ ++
Sbjct: 715 NT---YKCSCPRGTQGVHCEINVD 735
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C +G SC C C GY+G CET I + C +PC
Sbjct: 381 DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDI-----------DDCRPNPCH 429
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N+ CDC G+ G C+
Sbjct: 430 NGGSCTDGINTAF---CDCLPGFRGTFCE 455
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C + G C C CP G+TG C+ V+ C+ PC+NG C
Sbjct: 8 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQY-----------DVDECASTPCKNGAKCL 56
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N+ +TC C GY G C++ ++
Sbjct: 57 DGPNT---YTCVCTEGYTGTHCEVDID 80
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C S C C PG++G+ C+ N C +PC NGGTCK D S
Sbjct: 240 GACRDSLNGYKCDCDPGWSGTNCDINN-----------NECESNPCVNGGTCK-DMTS-- 285
Query: 235 NHTCDCPLGYAGASCQ 282
+ C C G++G +CQ
Sbjct: 286 GYVCTCREGFSGPNCQ 301
Score = 47.2 bits (107), Expect = 6e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPC 192
D + S +C NGG+C + S C+C +TG C+ P +PC +PC
Sbjct: 860 DARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF----------PASSPCLGGNPC 909
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
N GTC+P S + C CP + G C +
Sbjct: 910 YNQGTCEPTSESPF-YRCLCPAKFNGLLCHI 939
Score = 46.8 bits (106), Expect = 9e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NG C + C+C GYTG++CE ++ C PC
Sbjct: 40 DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV-----------DIDECDPDPC- 87
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G+CK + TC C GY G C+
Sbjct: 88 HYGSCK---DGVATFTCLCRPGYTGHHCE 113
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 34 SESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
S S +C N G+C + +C CPPG+ G CE VN C +PC GT
Sbjct: 745 SRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----------GDVNECLSNPCDARGT 793
Query: 208 --CKPDRNSWMNHTCDCPLGYAGASCQ 282
C N + H C+C G+ G C+
Sbjct: 794 QNCVQRVNDF--H-CECRAGHTGRRCE 817
Score = 38.3 bits (85), Expect = 0.030
Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C +GG+C C C G TG CE + + C+ PC
Sbjct: 115 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINL-----------DDCASSPC- 162
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ GTC + + C C GY G+ C + ++
Sbjct: 163 DSGTCLDKID---GYECACEPGYTGSMCNINID 192
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/40 (32%), Positives = 20/40 (50%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C+ PC + G C N + C+CP G+ G CQ ++
Sbjct: 6 CASSPCLHNGRCLDKINEFQ---CECPTGFTGHLCQYDVD 42
>U77493-1|AAB19224.1| 263|Homo sapiens Notch2 protein.
Length = 263
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 24 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLND 71
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 72 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 100
Score = 57.2 bits (132), Expect = 6e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 59 EINECSSHPCLNDGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 107
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + S C CP G+ GA C +P
Sbjct: 108 NKGTCVQKKAS---PQCLCPSGWVGAYCDVP 135
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+N G+C + S C+CP G+ G+YC+ S ++ H C++ G C
Sbjct: 106 CKNKGTCVQKKASPQCLCPSGWVGAYCDVPNVSCDIAASRR-GVLVEHLCQHSGVC---I 161
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N+ H C CP+GY G+ C+ L+
Sbjct: 162 NAGNTHYCQCPVGYTGSYCEEQLD 185
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 154 CQHSGVCINAGNTHYCQCPVGYTGSYCEEQL-----------DECASNPCQHGATCS--- 199
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 200 DFIGGYRCECVPGYQGVNCEYEVD 223
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 178 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 226
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 282
PC+NGGTC +NH C CP G G C+
Sbjct: 227 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 257
Score = 44.0 bits (99), Expect = 6e-04
Identities = 24/67 (35%), Positives = 32/67 (47%)
Frame = +1
Query: 79 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 258
S C C G+ G +CE I N C+ C NGGTC NS+ +C CP+
Sbjct: 4 SYTCKCQAGFDGVHCENNI-----------NECTESSCFNGGTCVDGINSF---SCLCPV 49
Query: 259 GYAGASC 279
G+ G+ C
Sbjct: 50 GFTGSFC 56
Score = 34.7 bits (76), Expect = 0.37
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRI 135
++ ++ C+NGG+C C CPPG G CE I
Sbjct: 221 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI 260
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 68.5 bits (160), Expect = 2e-11
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
NGGTC NS +TC C G+ G C+ + E +S FNG V+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Score = 68.1 bits (159), Expect = 3e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+T +R +I + +C+NGG C + NC CPP +TG +C + L+ P
Sbjct: 254 GSTCER-NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP------ 306
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ C+NGGTC +RN + C C G++G C
Sbjct: 307 ---NACQNGGTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 52.4 bits (120), Expect = 2e-06
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 7e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 282
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 159
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PC+N TC + TC C G+ G C++ + QS NG
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQSNPCVNNG 507
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPL 291
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +1
Query: 43 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 189
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +1
Query: 61 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 235 NHTCDCPLGYAGASCQMPLE 294
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 226 SWMNHTCDCPLGYAGASCQM 285
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 265 AGASC 279
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +1
Query: 40 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 198
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 199 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 291
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.49
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 216
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C G +C CICP G C ++ VN C +PC
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------VNECLSNPCI 730
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ G C + C C G+ G +C++
Sbjct: 731 H-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 68.5 bits (160), Expect = 2e-11
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
NGGTC NS +TC C G+ G C+ + E +S FNG V+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Score = 68.1 bits (159), Expect = 3e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+T +R +I + +C+NGG C + NC CPP +TG +C + L+ P
Sbjct: 254 GSTCER-NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP------ 306
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ C+NGGTC +RN + C C G++G C
Sbjct: 307 ---NACQNGGTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 52.4 bits (120), Expect = 2e-06
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 7e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 282
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 159
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PC+N TC + TC C G+ G C++ + QS NG
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQSNPCVNNG 507
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPL 291
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +1
Query: 43 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 189
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +1
Query: 61 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 235 NHTCDCPLGYAGASCQMPLE 294
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 226 SWMNHTCDCPLGYAGASCQM 285
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 265 AGASC 279
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +1
Query: 40 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 198
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 199 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 291
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.49
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 216
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C G +C CICP G C ++ VN C +PC
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------VNECLSNPCI 730
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ G C + C C G+ G +C++
Sbjct: 731 H-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 68.5 bits (160), Expect = 2e-11
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
NGGTC NS +TC C G+ G C+ + E +S FNG V+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Score = 68.1 bits (159), Expect = 3e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+T +R +I + +C+NGG C + NC CPP +TG +C + L+ P
Sbjct: 254 GSTCER-NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP------ 306
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ C+NGGTC +RN + C C G++G C
Sbjct: 307 ---NACQNGGTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 52.4 bits (120), Expect = 2e-06
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 7e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 282
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 159
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PC+N TC + TC C G+ G C++ + QS NG
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQSNPCVNNG 507
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPL 291
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +1
Query: 43 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 189
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +1
Query: 61 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 235 NHTCDCPLGYAGASCQMPLE 294
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 226 SWMNHTCDCPLGYAGASCQM 285
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 265 AGASC 279
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +1
Query: 40 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 198
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 199 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 291
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.49
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 216
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C G +C CICP G C ++ VN C +PC
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------VNECLSNPCI 730
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ G C + C C G+ G +C++
Sbjct: 731 H-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein.
Length = 2471
Score = 68.5 bits (160), Expect = 2e-11
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
NGGTC NS +TC C G+ G C+ + E +S FNG V+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Score = 68.1 bits (159), Expect = 3e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+T +R +I + +C+NGG C + NC CPP +TG +C + L+ P
Sbjct: 254 GSTCER-NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP------ 306
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ C+NGGTC +RN + C C G++G C
Sbjct: 307 ---NACQNGGTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 52.4 bits (120), Expect = 2e-06
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 50.4 bits (115), Expect = 7e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 282
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 159
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 46.0 bits (104), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PC+N TC + TC C G+ G C++ + QS NG
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQSNPCVNNG 507
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPL 291
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 199 LNLPGSYQCQCLQGFTGQYC 218
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +1
Query: 43 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 189
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +1
Query: 61 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 235 NHTCDCPLGYAGASCQMPLE 294
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 226 SWMNHTCDCPLGYAGASCQM 285
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 265 AGASC 279
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +1
Query: 40 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 198
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 199 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 291
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.49
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 216
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C G +C CICP G C ++ VN C +PC
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------VNECLSNPCI 730
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ G C + C C G+ G +C++
Sbjct: 731 H-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein.
Length = 2471
Score = 68.5 bits (160), Expect = 2e-11
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C+NGGSC + +C+C PG+TG C+T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQT-----------DMNECLSEPCK 959
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
NGGTC NS +TC C G+ G C+ + E +S FNG V+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Score = 68.1 bits (159), Expect = 3e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.0 bits (129), Expect = 1e-07
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NGG+CS S C C G+ G +CE I N C+ C
Sbjct: 949 DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NECTESSCF 997
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC NS+ +C CP+G+ G+ C
Sbjct: 998 NGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+T +R +I + +C+NGG C + NC CPP +TG +C + L+ P
Sbjct: 254 GSTCER-NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP------ 306
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ C+NGGTC +RN + C C G++G C
Sbjct: 307 ---NACQNGGTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/92 (36%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST-ESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GDI S C + GS + TN C+C +TG +CET V+ C
Sbjct: 1263 GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETF-----------VDVCPQM 1311
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC NGGTC N C CP G++GA CQ
Sbjct: 1312 PCLNGGTCAVASNMPDGFICRCPPGFSGARCQ 1343
Score = 52.4 bits (120), Expect = 2e-06
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.4 bits (115), Expect = 7e-06
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N++ +C C G+ G CQ
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKCQ 947
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 3/95 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQ 282
PC+NGGTC +NH C CP G G C+
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGLLCE 1223
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 23/102 (22%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIAS------------------YLMSPP 159
C NGG+C+ S C CPPG++G+ C++ + SP
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ C+ PC++GG+C P R ++C C ++G+ C++
Sbjct: 1373 DCESGCASSPCQHGGSCHPQRQP-PYYSCQCAPPFSGSRCEL 1413
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PC+N TC + TC C G+ G C++ + QS NG
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQSNPCVNNG 507
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ ++ C+NGG+C C CPPG G CE I P H C
Sbjct: 1187 EVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGP---------H-CL 1236
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG C DR ++C C G+AG C+
Sbjct: 1237 NGGQCM-DRIG--GYSCRCLPGFAGERCE 1262
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPL 291
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +1
Query: 43 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 189
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +1
Query: 61 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 235 NHTCDCPLGYAGASCQMPLE 294
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 226 SWMNHTCDCPLGYAGASCQM 285
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 265 AGASC 279
SC
Sbjct: 713 HHPSC 717
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/95 (29%), Positives = 37/95 (38%), Gaps = 11/95 (11%)
Frame = +1
Query: 40 SCQCENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN--- 198
S C++GGSC + +C C P ++GS CE Y P P C C +
Sbjct: 1380 SSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YTAPPSTPPATCLSQYCADKAR 1435
Query: 199 GGTCKPDRNS----WMNHTCDCPLGYAGASCQMPL 291
G C NS W C + A+C PL
Sbjct: 1436 DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Score = 34.3 bits (75), Expect = 0.49
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT--CKP 216
C NGG C +C C PG+ G CE +N C +PC + G+ C
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCE-----------GDINECLSNPCSSEGSLDCIQ 1283
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N ++ C C + G C+
Sbjct: 1284 LTNDYL---CVCRSAFTGRHCE 1302
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C G +C CICP G C ++ VN C +PC
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------VNECLSNPCI 730
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ G C + C C G+ G +C++
Sbjct: 731 H-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>BC071562-1|AAH71562.2| 1235|Homo sapiens NOTCH2 protein protein.
Length = 1235
Score = 68.1 bits (159), Expect = 3e-11
Identities = 37/92 (40%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Frame = +1
Query: 28 QASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ +ES C NGG+C S +C+CP G+TGS+C I N CS HPC N
Sbjct: 990 ECTES-SCFNGGTCVDGINSFSCLCPVGFTGSFCLHEI-----------NECSSHPCLNE 1037
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
GTC + + C CPLGY G +CQ + L
Sbjct: 1038 GTCVDGLGT---YRCSCPLGYTGKNCQTLVNL 1066
Score = 64.1 bits (149), Expect = 5e-10
Identities = 38/108 (35%), Positives = 53/108 (49%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C+NGGSC + +C+C PG+TG +T +N C PC+
Sbjct: 911 DIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKYQT-----------DMNECLSEPCK 959
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
NGGTC NS +TC C G+ G C+ + E +S FNG V+
Sbjct: 960 NGGTCSDYVNS---YTCKCQAGFDGVHCENNINECTESSCFNGGTCVD 1004
Score = 57.6 bits (133), Expect = 5e-08
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + C CP GYTG C+T VN CS PC+
Sbjct: 1025 EINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-----------VNLCSRSPCK 1073
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
N GTC + C CP G+AGA C +P
Sbjct: 1074 NKGTCVQKK---AESQCLCPSGWAGAYCDVP 1101
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+ Y D+ S C+NGG+CS S C C G+ G +CE I N
Sbjct: 943 GDKYQT-DMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNI-----------NE 990
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C+ C NGGTC NS+ +C CP+G+ G+ C
Sbjct: 991 CTESSCFNGGTCVDGINSF---SCLCPVGFTGSFC 1022
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C CP G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
C+C G+ G++C+ ++
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNID 262
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G+T +R +I + +C+NGG C + NC CPP +TG +C + L+ P
Sbjct: 254 GSTCER-NIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP------ 306
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ C+NGGTC +RN + C C G++G C
Sbjct: 307 ---NACQNGGTC-ANRNG--GYGCVCVNGWSGDDC 335
Score = 52.4 bits (120), Expect = 2e-06
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C+N +C + C+C PG+ G +CE I N C +PC
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI-----------NECQSNPCV 504
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N G C N + C CP G+ G CQ+ ++
Sbjct: 505 NNGQCVDKVNRFQ---CLCPPGFTGPVCQIDID 534
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++ G C C CP GYTGSYCE ++ + C+ +PC++G TC
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQL-----------DECASNPCQHGATCS--- 1165
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + C+C GY G +C+ ++
Sbjct: 1166 DFIGGYRCECVPGYQGVNCEYEVD 1189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I +S C N G C C+CPPG+TG C+ ++ CS PC
Sbjct: 494 EINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQI-----------DIDDCSSTPCL 542
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NG C N + C C G+ G C+
Sbjct: 543 NGAKCIDHPN---GYECQCATGFTGVLCE 568
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +1
Query: 49 CENGGSCST----ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
CEN C ES C+C PG+ G C ++ C PC N G C
Sbjct: 842 CENAAVCKESPNFESYTCLCAPGWQGQRCTI-----------DIDECISKPCMNHGLCHN 890
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLE 294
+ S+M C+CP G++G C+ ++
Sbjct: 891 TQGSYM---CECPPGFSGMDCEEDID 913
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C N G+C + + C C YTG C+T +A PCS +PC
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLA-----------PCSPNPCE 843
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
N CK N + ++TC C G+ G C + ++
Sbjct: 844 NAAVCKESPN-FESYTCLCAPGWQGQRCTIDID 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C CP G+ G C
Sbjct: 199 LNLPGSYQCQCPQGFTGQYC 218
Score = 46.0 bits (104), Expect = 1e-04
Identities = 33/109 (30%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC-STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T D + + S CE+ G C +T+ +C C GY G CE I N C
Sbjct: 413 TEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDI-----------NECH 461
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PC+N TC + TC C G+ G C++ + QS NG
Sbjct: 462 SDPCQNDATCLDKIGGF---TCLCMPGFKGVHCELEINECQSNPCVNNG 507
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C N G C +T+ S C CPPG++G CE ++ C +PC+
Sbjct: 873 DIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCE-----------EDIDDCLANPCQ 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGG+C N++ +C C G+ G Q
Sbjct: 922 NGGSCMDGVNTF---SCLCLPGFTGDKYQ 947
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
+Y + S C++G +CS C C PGY G CE V+ C
Sbjct: 1144 SYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYE-----------VDECQ 1192
Query: 181 LHPCRNGGTCKPDRNSWMNH-TCDCPLGYAGASCQMPL 291
PC+NGGTC +NH C CP G G + +
Sbjct: 1193 NQPCQNGGTC----IDLVNHFKCSCPPGTRGMKSSLSI 1226
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Frame = +1
Query: 49 CENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C G C T N C CP GY G+ C + M+ + +PC + G C
Sbjct: 384 CHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMA--------NSNPCEHAGKCVN 435
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPL 291
++ H C+C GYAG C+M +
Sbjct: 436 TDGAF--H-CECLKGYAGPRCEMDI 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 11/90 (12%)
Frame = +1
Query: 43 CQCENGGS---CSTESTNCICPPGYTGSYCETRIASY-LMSPPPPV-------NPCSLHP 189
C C NG S CS +C GS C R+AS+ M P + C +P
Sbjct: 324 CVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNP 383
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C G C + + + C CP GY GA C
Sbjct: 384 CHKGALCDTNPLNGQ-YICTCPQGYKGADC 412
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%)
Frame = +1
Query: 61 GSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ C+C G+ G CE N C +PC+NGGTC N
Sbjct: 732 GNCTGGLSGYKCLCDAGWVGINCEV-----------DKNECLSNPCQNGGTCD---NLVN 777
Query: 235 NHTCDCPLGYAGASCQMPLE 294
+ C C G+ G +CQ+ ++
Sbjct: 778 GYRCTCKKGFKGYNCQVNID 797
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/80 (31%), Positives = 37/80 (46%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
QC++G +S CIC PGY G+ C +I + C PC N G C N
Sbjct: 583 QCQDG----IDSYTCICNPGYMGAICSDQI-----------DECYSSPCLNDGRCIDLVN 627
Query: 226 SWMNHTCDCPLGYAGASCQM 285
+ C+C G +G +C++
Sbjct: 628 GYQ---CNCQPGTSGVNCEI 644
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NG C C C G+TG CE I + C PC
Sbjct: 532 DIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENI-----------DNCDPDPCH 580
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+ G C+ +S +TC C GY GA C
Sbjct: 581 H-GQCQDGIDS---YTCICNPGYMGAIC 604
Score = 39.1 bits (87), Expect = 0.017
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C ++ C+ +PCR G TC N + C CP G
Sbjct: 667 SCVCSPGFTGQRCNI-----------DIDECASNPCRKGATCINGVNGF---RCICPEGP 712
Query: 265 AGASC 279
SC
Sbjct: 713 HHPSC 717
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/90 (26%), Positives = 34/90 (37%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C G +C CICP G C ++ VN C +PC
Sbjct: 682 DIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ-----------VNECLSNPCI 730
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
+ G C + C C G+ G +C++
Sbjct: 731 H-GNC---TGGLSGYKCLCDAGWVGINCEV 756
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N G C C C PG +G CE + C+ +PC + G C
Sbjct: 613 SSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINF-----------DDCASNPCIH-GICM 660
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++C C G+ G C + ++
Sbjct: 661 DGIN---RYSCVCSPGFTGQRCNIDID 684
>AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.
Length = 4186
Score = 67.3 bits (157), Expect = 6e-11
Identities = 59/207 (28%), Positives = 90/207 (43%), Gaps = 11/207 (5%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC+N G C W + +CDCP+G+ G CQ L + F GNG +
Sbjct: 1796 CDSGPCKNSGFCS---ERWGSFSCDCPVGFGGKDCQ--LTMAHPHHFRGNGTLSWN---F 1847
Query: 355 RYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
D S P + LA T GVL + QA P+ L +++RG + + G G
Sbjct: 1848 GSDMAVSVPWYLGLAFRTRATQGVL---MQVQAGPH--STLLCQLDRGLLSVTVTRGSGR 1902
Query: 532 SS-IVVD-VPINDGERHQVAARLHED-----GHAWLSVD---GVDKSAPATGISNVMNAD 681
+S +++D V ++DG H + L E+ GH L V + + A G
Sbjct: 1903 ASHLLLDQVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTMAVGSELQGLKV 1962
Query: 682 SNIYIGGIPSWLNIHGYPGFIGCIENV 762
+++GG+P G +GCI+ V
Sbjct: 1963 KQLHVGGLPPGSAEEAPQGLVGCIQGV 1989
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+TG +CET + + C +PCRNGG C +TC C +
Sbjct: 1491 CRCPPGFTGDFCETEL-----------DLCYSNPCRNGGACARREG---GYTCVCRPRFT 1536
Query: 268 GASCQMPLELGQSV-GFNGNG 327
G C++ E G+ V G NG
Sbjct: 1537 GEDCELDTEAGRCVPGVCRNG 1557
Score = 46.4 bits (105), Expect = 1e-04
Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 6/189 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ C+C P +TG CE + C CRNGGTC
Sbjct: 1514 CRNGGACARREGGYTCVCRPRFTGEDCELDTEA---------GRCVPGVCRNGGTCTDAP 1564
Query: 223 NSWMNHTCDCPLG--YAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIAL 396
N C CP G + G C++ F + +V R+ S ++
Sbjct: 1565 NG--GFRCQCPAGGAFEGPRCEVAAR-----SFPPSSFVMFRGLRQRFHLTLS----LSF 1613
Query: 397 AVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVP--INDGE 570
A G+L Y G+ + D+ L + G V L + G + + VP ++DG+
Sbjct: 1614 AT-VQQSGLLFY--NGRL-NEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQ 1669
Query: 571 RHQVAARLH 597
H V R +
Sbjct: 1670 WHTVHLRYY 1678
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/69 (33%), Positives = 34/69 (49%)
Frame = +1
Query: 76 ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
++ +C C PGY G C V+ C L+PC+N G+C+ + +TCDC
Sbjct: 2036 QTFSCTCQPGYYGPGC--------------VDACLLNPCQNQGSCRHLPGAPHGYTCDCV 2081
Query: 256 LGYAGASCQ 282
GY G C+
Sbjct: 2082 GGYFGHHCE 2090
>AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo 1
protein.
Length = 3312
Score = 67.3 bits (157), Expect = 6e-11
Identities = 59/207 (28%), Positives = 90/207 (43%), Gaps = 11/207 (5%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC+N G C W + +CDCP+G+ G CQ L + F GNG +
Sbjct: 1726 CDSGPCKNSGFCS---ERWGSFSCDCPVGFGGKDCQ--LTMAHPHHFRGNGTLSWN---F 1777
Query: 355 RYDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
D S P + LA T GVL + QA P+ L +++RG + + G G
Sbjct: 1778 GSDMAVSVPWYLGLAFRTRATQGVL---MQVQAGPH--STLLCQLDRGLLSVTVTRGSGR 1832
Query: 532 SS-IVVD-VPINDGERHQVAARLHED-----GHAWLSVD---GVDKSAPATGISNVMNAD 681
+S +++D V ++DG H + L E+ GH L V + + A G
Sbjct: 1833 ASHLLLDQVTVSDGRWHDLRLELQEEPGGRRGHHVLMVSLDFSLFQDTMAVGSELQGLKV 1892
Query: 682 SNIYIGGIPSWLNIHGYPGFIGCIENV 762
+++GG+P G +GCI+ V
Sbjct: 1893 KQLHVGGLPPGSAEEAPQGLVGCIQGV 1919
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+TG +CET + + C +PCRNGG C +TC C +
Sbjct: 1421 CRCPPGFTGDFCETEL-----------DLCYSNPCRNGGACARREG---GYTCVCRPRFT 1466
Query: 268 GASCQMPLELGQSV-GFNGNG 327
G C++ E G+ V G NG
Sbjct: 1467 GEDCELDTEAGRCVPGVCRNG 1487
Score = 46.4 bits (105), Expect = 1e-04
Identities = 49/189 (25%), Positives = 74/189 (39%), Gaps = 6/189 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ C+C P +TG CE + C CRNGGTC
Sbjct: 1444 CRNGGACARREGGYTCVCRPRFTGEDCELDTEA---------GRCVPGVCRNGGTCTDAP 1494
Query: 223 NSWMNHTCDCPLG--YAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIAL 396
N C CP G + G C++ F + +V R+ S ++
Sbjct: 1495 NG--GFRCQCPAGGAFEGPRCEVAAR-----SFPPSSFVMFRGLRQRFHLTLS----LSF 1543
Query: 397 AVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVP--INDGE 570
A G+L Y G+ + D+ L + G V L + G + + VP ++DG+
Sbjct: 1544 AT-VQQSGLLFY--NGRL-NEKHDFLALELVAGQVRLTYSTGESNTVVSPTVPGGLSDGQ 1599
Query: 571 RHQVAARLH 597
H V R +
Sbjct: 1600 WHTVHLRYY 1608
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/69 (33%), Positives = 34/69 (49%)
Frame = +1
Query: 76 ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
++ +C C PGY G C V+ C L+PC+N G+C+ + +TCDC
Sbjct: 1966 QTFSCTCQPGYYGPGC--------------VDACLLNPCQNQGSCRHLPGAPHGYTCDCV 2011
Query: 256 LGYAGASCQ 282
GY G C+
Sbjct: 2012 GGYFGHHCE 2020
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 981
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1185
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 897 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 945
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 946 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 980
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 696 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 744
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 745 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 787
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 445 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 490
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 491 DLLATFHCLCPPGLEGQLCEV 511
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 281 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPP-------H-CRNGGTC- 331
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 332 --QNSAGSFHCVCVSGWGGTSCEENLD 356
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1004 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1052
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1053 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1083
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 400 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 451
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 452 -LNTPGSFNCLCPPGYTGSRCE 472
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 772 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 820
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 821 --QDSPQGPRCLCPTGYTGGSCQTLMDL 846
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 204 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 252
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 253 EKDSTF-HLCLCPPGFIGPGCEV 274
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 930 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 978
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 979 HGTCTPKPGGF--H-CACPPGFVGLRCE 1003
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 662 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 707
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 708 QPS---GYNCTCPTGYTGPTC 725
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 242 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVN----------PDN-CVSHQCQNGGTC 290
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 291 QDGLDT---YTCLCPETWTGWDCSEDVDECEAQG 321
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 728 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 776
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 777 NGGTCV---NRPGTFSCLCAMGFQGPRCE 802
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 550 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 598
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 599 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 627
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1045 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1093
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1094 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1127
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 107 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 156
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 157 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 191
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 164 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 211
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 212 NTLGSFQCLCPVGQEGPRCEL 232
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 518 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 566
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 567 DQPGAF--H-CKCLPGFEGPRCQTEVD 590
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 814 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 862
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 863 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 891
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 845 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 902
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 903 GGLCV---DSGPSYFCHCPPGFQGSLCQ 927
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
D + +A C NGG+C S S +C+C G+ G+ CE + + C
Sbjct: 313 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAA 361
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G TC DR + +C CP G G C +
Sbjct: 362 TCAPGSTC-IDRVG--SFSCLCPPGRTGLLCHL 391
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 483 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 531
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 532 NGFQ---CICLPGFSGTRCEEDID 552
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 23 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 72
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 73 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 118
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 347 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 394
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 395 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 433
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 597 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 656
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 657 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 691
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 73 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 122
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 123 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 155
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1095 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1146
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1147 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1184
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 981
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1185
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 981
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1185
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 981
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 50.0 bits (114), Expect = 9e-06
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP Y G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTVYTGGSCQTLMDL 847
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP YTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTVYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1185
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 981
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 50.0 bits (114), Expect = 9e-06
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP Y G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTVYTGGSCQTLMDL 847
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP YTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTVYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1185
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 947 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 981
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1053
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 979
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 980 HGTCTPKPGGF--H-CACPPGFVGLRCE 1004
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1046 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1094
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1095 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1096 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1147
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1148 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1185
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 900 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 948
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
+ ++ C C GY G +C L+ QS + +G
Sbjct: 949 AQPSGYL---CQCAPGYDGQNCSKELDACQSQPCHNHG 983
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 699 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 747
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 748 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 790
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 448 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 493
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 494 DLLATFHCLCPPGLEGQLCEV 514
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 284 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPP-------H-CRNGGTC- 334
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 335 --QNSAGSFHCVCVSGWGGTSCEENLD 359
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 1007 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 1055
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 1056 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1086
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 403 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 454
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 455 -LNTPGSFNCLCPPGYTGSRCE 475
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 775 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 823
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 824 --QDSPQGPRCLCPTGYTGGSCQTLMDL 849
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 207 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 255
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 256 EKDSTF-HLCLCPPGFIGPDCEV 277
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 933 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 981
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 982 HGTCTPKPGGF--H-CACPPGFVGLRCE 1006
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 665 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 710
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 711 QPS---GYNCTCPTGYTGPTC 728
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 245 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 293
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 294 QDGLDT---YTCLCPETWTGWDCSEDVDECEAQG 324
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 731 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 779
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 780 NGGTCV---NRPGTFSCLCAMGFQGPRCE 805
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 553 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 601
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 602 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 630
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 1048 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 1096
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 1097 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1130
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R Q + C C G C +++ C C PG+TG C+ R
Sbjct: 110 GFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 159
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 160 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 194
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 167 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 214
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 215 NTLGSFQCLCPVGQEGPRCEL 235
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 521 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 569
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 570 DQPGAF--H-CKCLPGFEGPRCQTEVD 593
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 817 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQKPCPRNSHCLQTG 865
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 866 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 894
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A + C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 848 DLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 905
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 906 GGLCV---DSGPSYFCHCPPGFQGSLCQ 930
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
D + +A C NGG+C S S +C+C G+ G+ CE + + C
Sbjct: 316 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAA 364
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G TC DR + +C CP G G C +
Sbjct: 365 TCAPGSTC-IDRVG--SFSCLCPPGRTGLLCHL 394
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 486 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 534
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 535 NGFQ---CICLPGFSGTRCEEDID 555
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 26 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 75
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 76 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE 121
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 350 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 397
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 398 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 436
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 600 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 659
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 660 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 694
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 1098 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 1149
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 1150 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 1187
Score = 35.1 bits (77), Expect = 0.28
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 76 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE----------DPCP 125
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 126 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 158
>U70312-1|AAC02648.1| 480|Homo sapiens integrin binding protein
Del-1 protein.
Length = 480
Score = 64.5 bits (150), Expect = 4e-10
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRI-ASYLMSPPPPVNP 174
+ +GDI + CENGG C + S +C CP G+T C + + + P P
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGP 77
Query: 175 CSLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 282
C+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 78 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 117
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +1
Query: 49 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 83 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 131
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQ 282
G C + N++C+CP + G +CQ
Sbjct: 132 GIC---TDLVANYSCECPGEFMGRNCQ 155
Score = 36.7 bits (81), Expect = 0.091
Identities = 14/41 (34%), Positives = 22/41 (53%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C +PC NGG C P + +C+CP G+ +C +E+
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEV 65
>BC030828-1|AAH30828.1| 480|Homo sapiens EGF-like repeats and
discoidin I-like domains 3 protein.
Length = 480
Score = 64.5 bits (150), Expect = 4e-10
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRI-ASYLMSPPPPVNP 174
+ +GDI + CENGG C + S +C CP G+T C + + + P P
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGP 77
Query: 175 CSLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 282
C+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 78 CTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 117
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +1
Query: 49 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 83 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 131
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQ 282
G C + N++C+CP + G +CQ
Sbjct: 132 GIC---TDLVANYSCECPGEFMGRNCQ 155
Score = 36.7 bits (81), Expect = 0.091
Identities = 14/41 (34%), Positives = 22/41 (53%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL 297
C +PC NGG C P + +C+CP G+ +C +E+
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEV 65
>AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive
sequence DNA binding protein-1 protein.
Length = 1008
Score = 64.1 bits (149), Expect = 5e-10
Identities = 37/102 (36%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G + G + S C NGG+C C CPPG++G YCE ++P +P
Sbjct: 227 GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRYCE-------IAP----SP 275
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C PC NGGTC+ DR++ + C C GY G CQ ++ G
Sbjct: 276 CFRSPCVNGGTCE-DRDT--DFFCHCQAGYMGRRCQAEVDCG 314
Score = 59.3 bits (137), Expect = 1e-08
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C +GGSC C+C GY G++CE + C HPCR
Sbjct: 368 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER-----------DECRAHPCR 416
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C RN + C CP G+ G C+ ++
Sbjct: 417 NGGSC---RNLPGAYVCRCPAGFVGVHCETEVD 446
Score = 57.6 bits (133), Expect = 5e-08
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSC +S C CP G+ G +CE + +L CS PCRNGGTCK
Sbjct: 165 CFNGGSCDAHDDSYTCECPRGFHGKHCE-KARPHL---------CSSGPCRNGGTCK--- 211
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ + C CP + G C++
Sbjct: 212 EAGGEYHCSCPYRFTGRHCEI 232
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A +S C++GG C + C+CP G+ G +CET +PC PC
Sbjct: 444 EVDACDSSPCQHGGRCESGGGAYLCVCPEGFFGYHCET-----------VSDPCFSSPCG 492
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G C S H+C C +GY G C L
Sbjct: 493 GRGYCLASNGS---HSCTCKVGYTGEDCAKEL 521
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSC + C CP G+ G +CET V+ C PC++GG C+
Sbjct: 415 CRNGGSCRNLPGAYVCRCPAGFVGVHCETE-----------VDACDSSPCQHGGRCESGG 463
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
+++ C CP G+ G C+ + S G GY
Sbjct: 464 GAYL---CVCPEGFFGYHCETVSDPCFSSPCGGRGY 496
Score = 51.6 bits (118), Expect = 3e-06
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ C NGGSC N C+C + G CET P + C PC
Sbjct: 2 DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCET-------GDHPVPDACLSAPCH 54
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC ++ + C+CP G+ G C+
Sbjct: 55 NGGTCV---DADQGYVCECPEGFMGLDCR 80
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 29/111 (26%)
Frame = +1
Query: 37 ESCQCENGGSC-STESTNCICPPGY---------------------TGSYCETRIASYLM 150
+ C+C NGG C +T C CP G+ G YC SYL
Sbjct: 85 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 144
Query: 151 SPPPPVN-------PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N PC+ PC NGG+C +S +TC+CP G+ G C+
Sbjct: 145 VCHTDHNASHSLPSPCNSDPCFNGGSCDAHDDS---YTCECPRGFHGKHCE 192
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 5/98 (5%)
Frame = +1
Query: 13 DRGDIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
+ GD ++C C NGG+C + + C CP G+ G C R+ + C
Sbjct: 38 ETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP----------DDC 87
Query: 178 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CRNGG C + C CPLG+ G C+ +
Sbjct: 88 E---CRNGGRCLGANTT----LCQCPLGFFGLLCEFEI 118
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 906 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 939
Score = 34.3 bits (75), Expect = 0.49
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 911 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 966
>BC110320-1|AAI10321.1| 383|Homo sapiens delta-like 2 homolog
(Drosophila) protein.
Length = 383
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G D+ + + C+NGG C + +C+C PG+ G CE +
Sbjct: 85 GKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AG 133
Query: 172 PCSL--HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC PCRNGG C+ D+ +N TC C +G+ GA C++ ++
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 176
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 183 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 230
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP GY G +C++ L
Sbjct: 231 VH--DFDCLCPSGYGGKTCELVL 251
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 190
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N + +C CP G+AG C + L+
Sbjct: 191 DGINRF---SCLCPEGFAGRFCTINLD 214
Score = 33.9 bits (74), Expect = 0.64
Identities = 21/78 (26%), Positives = 36/78 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++G +C + CIC G+ G +C+ ++ + + PC+NGG C D
Sbjct: 66 CQHG-TCH-QPWQCICHSGWAGKFCDK--DEHICT--------TQSPCQNGGQCMYDGGG 113
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C C G+ G C+
Sbjct: 114 --EYHCVCLPGFHGRDCE 129
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 257
>BC035009-1|AAH35009.1| 737|Homo sapiens delta/notch-like EGF
repeat containing protein.
Length = 737
Score = 63.7 bits (148), Expect = 7e-10
Identities = 38/107 (35%), Positives = 54/107 (50%), Gaps = 10/107 (9%)
Frame = +1
Query: 37 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 399
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PCRNG TC +S TC CP GY G++C+ ++L S NG
Sbjct: 400 PCRNGATC---ISSLSGFTCQCPEGYFGSACEEKVDLCASSPCQNNG 443
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 600
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G+ GA+C++ L+
Sbjct: 601 N---GYNCHCPHGWVGANCEIHLQ 621
Score = 54.4 bits (125), Expect = 4e-07
Identities = 29/79 (36%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C S C CP GY GS CE + V+ C+ PC+N GTC D
Sbjct: 401 CRNGATCISSLSGFTCQCPEGYFGSACEEK-----------VDLCASSPCQNNGTCYVD- 448
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ TC+C G+ G +C
Sbjct: 449 --GVHFTCNCSPGFTGPTC 465
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
G+ A++ +C G C+T E+T +C C Y G++CE + C
Sbjct: 310 GESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE------------EYDACQRK 356
Query: 187 PCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC+N +C ++ N TC C GY G CQ ++
Sbjct: 357 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
++ D+ AS CQ N G+C + + C C PG+TG C I + C+L
Sbjct: 429 EKVDLCASSPCQ--NNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALS 475
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC + GTC R+ ++ C C GY G C+
Sbjct: 476 PCAH-GTC---RSVGTSYKCLCDPGYHGLYCE 503
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +1
Query: 61 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 525
Query: 235 NHTCDCPLGYAGASCQM 285
+ C C Y G C++
Sbjct: 526 GYECVCLAEYKGTHCEL 542
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 9/54 (16%)
Frame = +1
Query: 151 SPPPPVNPCSLHPCRNGGTC----KPDRN-----SWMNHTCDCPLGYAGASCQM 285
+P PC+ PCRNGG C +PD ++C CP G +GA+CQ+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 559
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
D +N TC C G+ G C + +
Sbjct: 560 SD---GLNGTCICAPGFTGEECDIDI 582
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C CP G +G+ C+ +PC+ +PC +G +S + C C GY
Sbjct: 79 SCTCPAGISGANCQL-----------VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 265 AGASCQMPL 291
G +C+ L
Sbjct: 128 EGPNCEQAL 136
Score = 31.1 bits (67), Expect = 4.5
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Frame = +1
Query: 31 ASESCQ---CENGGSCSTESTNCICPPGYTGSYCETRIAS 141
AS C C + S S++ CIC GY G CE + S
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
>AY358126-1|AAQ88493.1| 383|Homo sapiens PSGC2903 protein.
Length = 383
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G D+ + + C+NGG C + +C+C PG+ G CE +
Sbjct: 85 GKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AG 133
Query: 172 PCSL--HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC PCRNGG C+ D+ +N TC C +G+ GA C++ ++
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 176
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 183 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 230
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP GY G +C++ L
Sbjct: 231 VH--DFDCLCPSGYGGKTCELVL 251
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 190
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N + +C CP G+AG C + L+
Sbjct: 191 DGINRF---SCLCPEGFAGRFCTINLD 214
Score = 33.9 bits (74), Expect = 0.64
Identities = 21/78 (26%), Positives = 36/78 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++G +C + CIC G+ G +C+ ++ + + PC+NGG C D
Sbjct: 66 CQHG-TCH-QPWQCICHSGWAGKFCDK--DEHICT--------TQSPCQNGGQCMYDGGG 113
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C C G+ G C+
Sbjct: 114 --EYHCVCLPGFHGRDCE 129
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 257
>AL359813-9|CAI23224.1| 383|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 383
Score = 63.7 bits (148), Expect = 7e-10
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVN 171
G D+ + + C+NGG C + +C+C PG+ G CE +
Sbjct: 85 GKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AG 133
Query: 172 PCSL--HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC PCRNGG C+ D+ +N TC C +G+ GA C++ ++
Sbjct: 134 PCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVD 176
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 183 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 230
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP GY G +C++ L
Sbjct: 231 VH--DFDCLCPSGYGGKTCELVL 251
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 142 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 190
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N + +C CP G+AG C + L+
Sbjct: 191 DGINRF---SCLCPEGFAGRFCTINLD 214
Score = 33.9 bits (74), Expect = 0.64
Identities = 21/78 (26%), Positives = 36/78 (46%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++G +C + CIC G+ G +C+ ++ + + PC+NGG C D
Sbjct: 66 CQHG-TCH-QPWQCICHSGWAGKFCDK--DEHICT--------TQSPCQNGGQCMYDGGG 113
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C C G+ G C+
Sbjct: 114 --EYHCVCLPGFHGRDCE 129
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 221 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 257
>BC024766-1|AAH24766.2| 454|Homo sapiens DNER protein protein.
Length = 454
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 269 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 317
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G+ GA+C++ L+
Sbjct: 318 N---GYNCHCPHGWVGANCEIHLQ 338
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 10/107 (9%)
Frame = +1
Query: 37 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 68 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 116
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PCRNG TC +S TC CP GY G++C+ ++ S NG
Sbjct: 117 PCRNGATC---ISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNG 160
Score = 58.4 bits (135), Expect = 3e-08
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C S C CP GY GS CE + V+PC+ PC+N GTC D
Sbjct: 118 CRNGATCISSLSGFTCQCPEGYFGSACEEK-----------VDPCASSPCQNNGTCYVD- 165
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ TC+C G+ G +C
Sbjct: 166 --GVHFTCNCSPGFTGPTC 182
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
G+ A++ +C G C+T E+T +C C Y G++CE + C
Sbjct: 27 GESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE------------EYDACQRK 73
Query: 187 PCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC+N +C ++ N TC C GY G CQ ++
Sbjct: 74 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 111
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 153 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 199
Query: 214 PDRNSWMNHTCDCPLGYAGASCQ 282
R+ ++ C C GY G C+
Sbjct: 200 --RSVGTSYKCLCDPGYHGLYCE 220
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +1
Query: 61 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 197 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 242
Query: 235 NHTCDCPLGYAGASCQM 285
+ C C Y G C++
Sbjct: 243 GYECVCLAEYKGTHCEL 259
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 228 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 276
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
D +N TC C G+ G C + +
Sbjct: 277 SD---GLNGTCICAPGFTGEECDIDI 299
>AY358891-1|AAQ89250.1| 737|Homo sapiens QPRR262 protein.
Length = 737
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 600
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G+ GA+C++ L+
Sbjct: 601 N---GYNCHCPHGWVGANCEIHLQ 621
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 10/107 (9%)
Frame = +1
Query: 37 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 399
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PCRNG TC +S TC CP GY G++C+ ++ S NG
Sbjct: 400 PCRNGATC---ISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNG 443
Score = 58.4 bits (135), Expect = 3e-08
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C S C CP GY GS CE + V+PC+ PC+N GTC D
Sbjct: 401 CRNGATCISSLSGFTCQCPEGYFGSACEEK-----------VDPCASSPCQNNGTCYVD- 448
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ TC+C G+ G +C
Sbjct: 449 --GVHFTCNCSPGFTGPTC 465
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
G+ A++ +C G C+T E+T +C C Y G++CE + C
Sbjct: 310 GESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE------------EYDACQRK 356
Query: 187 PCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC+N +C ++ N TC C GY G CQ ++
Sbjct: 357 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 482
Query: 214 PDRNSWMNHTCDCPLGYAGASCQ 282
R+ ++ C C GY G C+
Sbjct: 483 --RSVGTSYKCLCDPGYHGLYCE 503
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +1
Query: 61 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 525
Query: 235 NHTCDCPLGYAGASCQM 285
+ C C Y G C++
Sbjct: 526 GYECVCLAEYKGTHCEL 542
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 9/54 (16%)
Frame = +1
Query: 151 SPPPPVNPCSLHPCRNGGTC----KPDRN-----SWMNHTCDCPLGYAGASCQM 285
+P PC+ PCRNGG C +PD ++C CP G +GA+CQ+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 559
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
D +N TC C G+ G C + +
Sbjct: 560 SD---GLNGTCICAPGFTGEECDIDI 582
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C CP G +G+ C+ +PC+ +PC +G +S + C C GY
Sbjct: 79 SCTCPAGISGANCQL-----------VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 265 AGASCQMPL 291
G +C+ L
Sbjct: 128 EGPNCEQAL 136
Score = 31.1 bits (67), Expect = 4.5
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Frame = +1
Query: 31 ASESCQ---CENGGSCSTESTNCICPPGYTGSYCETRIAS 141
AS C C + S S++ CIC GY G CE + S
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1402
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
NS ++C C G++G C E QS GFN
Sbjct: 1403 NS---YSCKCQPGFSGKRC----ETEQSTGFN 1427
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1250
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
++ C+CP GY G C+
Sbjct: 1251 GEFI---CECPSGYTGQRCE 1267
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Frame = +1
Query: 31 ASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNP 174
A C C G C TE C P + CE ++ +L PP V+
Sbjct: 1289 AGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE 1348
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
C PC+NG TCK NS+ C C G+ G+ C++ + QS
Sbjct: 1349 CLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNINECQS 1389
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1231 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1279
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
N G C + + C C G+ G C+ + QS
Sbjct: 1280 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3479 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3520
Query: 229 WMNHTCDCPLGYAGASC 279
+ CDCP G+ G+ C
Sbjct: 3521 ---YQCDCPPGWTGSRC 3534
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 222
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3511 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3555
Query: 223 ---NSWMNHTC 246
+SW H C
Sbjct: 3556 HCLSSWTGHNC 3566
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C +PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1197 CFFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1233
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3468 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3506
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1331 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1379
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
NS ++C C G++G C E QS GFN
Sbjct: 1380 NS---YSCKCQPGFSGKRC----ETEQSTGFN 1404
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1227
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
++ C+CP GY G C+
Sbjct: 1228 GEFI---CECPSGYTGQRCE 1244
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Frame = +1
Query: 31 ASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNP 174
A C C G C TE C P + CE ++ +L PP V+
Sbjct: 1266 AGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE 1325
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
C PC+NG TCK NS+ C C G+ G+ C++ + QS
Sbjct: 1326 CLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNINECQS 1366
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1208 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1256
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
N G C + + C C G+ G C+ + QS
Sbjct: 1257 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1290
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3453 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3494
Query: 229 WMNHTCDCPLGYAGASC 279
+ CDCP G+ G+ C
Sbjct: 3495 ---YQCDCPPGWTGSRC 3508
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 222
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3485 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3529
Query: 223 ---NSWMNHTC 246
+SW H C
Sbjct: 3530 HCLSSWTGHNC 3540
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C +PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1174 CFFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1210
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3442 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3480
>AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven-pass
G-type receptor 2 (flamingo homolog, Drosophila) protein.
Length = 2923
Score = 62.9 bits (146), Expect = 1e-09
Identities = 68/210 (32%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
P N C + C NGGTC N W +C+CPLG+ G SC E+ F G+ V
Sbjct: 1572 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSCAQ--EMANPQHFLGSSLVA 1626
Query: 337 LPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVVLEW 513
L S P ++L T DGVL QA L++ G V+L
Sbjct: 1627 WHGLSLP----ISQPWYLSLMFRTRQADGVLL-----QAITRGRSTITLQLREGHVMLSV 1677
Query: 514 DLGGGL--SSIVVDV-PINDGERHQVAARLHED---GHAWLSVD-GVDKSAPATGISNVM 672
+ G GL SS+ ++ NDG+ H L GHA LS D G ++ G
Sbjct: 1678 E-GTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHG 1736
Query: 673 NADSNIYIGGIPSWLNIHGYPGFIGCIENV 762
SNI +GGIP GF GC++ V
Sbjct: 1737 LHLSNITVGGIPGPAG-GVARGFRGCLQGV 1765
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1274 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1319
Query: 268 GASCQMPLELGQ 303
G C++ G+
Sbjct: 1320 GEHCEVSARSGR 1331
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
+S C CS + S +C C PGY G C N C L+PC + C
Sbjct: 1798 DSNPCPANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVC 1843
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ +TC+CP Y G C+ ++
Sbjct: 1844 TRKPSAPHGYTCECPPNYLGPYCETRID 1871
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 7/203 (3%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1334
Query: 184 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQMPLELGQSVGFNGNGYVELPASLLR 357
C+NGGTC N + CDCP G + CQ+ F + ++ R
Sbjct: 1335 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQVTTR-----SFPAHSFITFRGLRQR 1386
Query: 358 YDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
+ +AL+ T DG+L Y + D+ L + + V L + G +
Sbjct: 1387 FH------FTLALSFATKERDGLLLYNGRFN---EKHDFVALEVIQEQVQLTFSAGESTT 1437
Query: 535 SIVVDVP--INDGERHQVAARLH 597
++ VP ++DG+ H V + +
Sbjct: 1438 TVSPFVPGGVSDGQWHTVQLKYY 1460
Score = 35.1 bits (77), Expect = 0.28
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC C N W +++C C GY G +C
Sbjct: 1795 DPCDSNPCPANSYCS---NDWDSYSCSCDPGYYGDNC 1828
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1331 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1379
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
NS ++C C G++G C E QS GFN
Sbjct: 1380 NS---YSCKCQPGFSGKRC----ETEQSTGFN 1404
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1227
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
++ C+CP GY G C+
Sbjct: 1228 GEFI---CECPSGYTGQRCE 1244
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Frame = +1
Query: 31 ASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNP 174
A C C G C TE C P + CE ++ +L PP V+
Sbjct: 1266 AGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE 1325
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
C PC+NG TCK NS+ C C G+ G+ C++ + QS
Sbjct: 1326 CLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNINECQS 1366
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1208 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1256
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
N G C + + C C G+ G C+ + QS
Sbjct: 1257 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1290
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3453 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3494
Query: 229 WMNHTCDCPLGYAGASC 279
+ CDCP G+ G+ C
Sbjct: 3495 ---YQCDCPPGWTGSRC 3508
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 222
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3485 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3529
Query: 223 ---NSWMNHTC 246
+SW H C
Sbjct: 3530 HCLSSWTGHNC 3540
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C +PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1174 CFFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1210
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3442 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3480
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1331 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1379
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
NS ++C C G++G C E QS GFN
Sbjct: 1380 NS---YSCKCQPGFSGKRC----ETEQSTGFN 1404
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1179 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1227
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
++ C+CP GY G C+
Sbjct: 1228 GEFI---CECPSGYTGQRCE 1244
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Frame = +1
Query: 31 ASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNP 174
A C C G C TE C P + CE ++ +L PP V+
Sbjct: 1266 AGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE 1325
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
C PC+NG TCK NS+ C C G+ G+ C++ + QS
Sbjct: 1326 CLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNINECQS 1366
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1208 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1256
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
N G C + + C C G+ G C+ + QS
Sbjct: 1257 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1290
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3453 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3494
Query: 229 WMNHTCDCPLGYAGASC 279
+ CDCP G+ G+ C
Sbjct: 3495 ---YQCDCPPGWTGSRC 3508
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 222
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3485 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3529
Query: 223 ---NSWMNHTC 246
+SW H C
Sbjct: 3530 HCLSSWTGHNC 3540
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C +PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1174 CFFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1210
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3442 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3480
>AL137311-1|CAB70690.1| 252|Homo sapiens hypothetical protein
protein.
Length = 252
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 67 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 115
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G+ GA+C++ L+
Sbjct: 116 N---GYNCHCPHGWVGANCEIHLQ 136
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 26 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 74
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
D +N TC C G+ G C + +
Sbjct: 75 SD---GLNGTCICAPGFTGEECDIDI 97
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/69 (33%), Positives = 28/69 (40%)
Frame = +1
Query: 79 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 258
S C+C PGY G YCE N C PC N TC+ N + C C
Sbjct: 3 SYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN---GYECVCLA 48
Query: 259 GYAGASCQM 285
Y G C++
Sbjct: 49 EYKGTHCEL 57
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens cDNA
FLJ14964 fis, clone PLACE4000581, moderately similar to
FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1121 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1169
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
NS ++C C G++G C E QS GFN
Sbjct: 1170 NS---YSCKCQPGFSGKRC----ETEQSTGFN 1194
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 969 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1017
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
++ C+CP GY G C+
Sbjct: 1018 GEFI---CECPSGYTGQRCE 1034
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Frame = +1
Query: 31 ASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNP 174
A C C G C TE C P + CE ++ +L PP V+
Sbjct: 1056 AGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE 1115
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
C PC+NG TCK NS+ C C G+ G+ C++ + QS
Sbjct: 1116 CLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNINECQS 1156
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 998 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1046
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
N G C + + C C G+ G C+ + QS
Sbjct: 1047 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1080
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C +PC N GTC+ + C CPLGY G C+ ++
Sbjct: 964 CFFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1000
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NG +C S C+C G+TGS+CE I N C +PCRN TC +
Sbjct: 1354 CKNGATCKDGANSFRCLCAAGFTGSHCELNI-----------NECQSNPCRNQATCVDEL 1402
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
NS ++C C G++G C E QS GFN
Sbjct: 1403 NS---YSCKCQPGFSGKRC----ETEQSTGFN 1427
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C+CP GYTG CET ++ CS PC N G CK
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCET-----------DIDECSPLPCLNNGVCKDLV 1250
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
++ C+CP GY G C+
Sbjct: 1251 GEFI---CECPSGYTGQRCE 1267
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Frame = +1
Query: 31 ASESCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPP---------VNP 174
A C C G C TE C P + CE ++ +L PP V+
Sbjct: 1289 AGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDE 1348
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
C PC+NG TCK NS+ C C G+ G+ C++ + QS
Sbjct: 1349 CLSQPCKNGATCKDGANSF---RCLCAAGFTGSHCELNINECQS 1389
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C N G C C CP GYTG CE I N CS PC
Sbjct: 1231 DIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI-----------NECSSSPCL 1279
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
N G C + + C C G+ G C+ + QS
Sbjct: 1280 NKGICV---DGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 3479 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 3520
Query: 229 WMNHTCDCPLGYAGASC 279
+ CDCP G+ G+ C
Sbjct: 3521 ---YQCDCPPGWTGSRC 3534
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 222
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 3511 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 3555
Query: 223 ---NSWMNHTC 246
+SW H C
Sbjct: 3556 HCLSSWTGHNC 3566
Score = 39.9 bits (89), Expect = 0.010
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C +PC N GTC+ + C CPLGY G C+ ++
Sbjct: 1197 CFFNPCHNSGTCQ---QLGRGYVCLCPLGYTGLKCETDID 1233
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 3468 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 3506
>AF442487-1|AAM21557.1| 737|Homo sapiens delta-notch-like EGF
repeat-containing transmembrane protein protein.
Length = 737
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C ++ N CIC PG+TG C+ I N C +PC +GG+C
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDI-----------NECDSNPCHHGGSCLDQP 600
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C CP G+ GA+C++ L+
Sbjct: 601 N---GYNCHCPHGWVGANCEIHLQ 621
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 10/107 (9%)
Frame = +1
Query: 37 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 351 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 399
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PCRNG TC +S TC CP GY G++C+ ++ S NG
Sbjct: 400 PCRNGATC---ISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNG 443
Score = 58.4 bits (135), Expect = 3e-08
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C S C CP GY GS CE + V+PC+ PC+N GTC D
Sbjct: 401 CRNGATCISSLSGFTCQCPEGYFGSACEEK-----------VDPCASSPCQNNGTCYVD- 448
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ TC+C G+ G +C
Sbjct: 449 --GVHFTCNCSPGFTGPTC 465
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
G+ A++ +C G C+T E+T +C C Y G++CE + C
Sbjct: 310 GESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE------------EYDACQRK 356
Query: 187 PCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC+N +C ++ N TC C GY G CQ ++
Sbjct: 357 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 436 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 482
Query: 214 PDRNSWMNHTCDCPLGYAGASCQ 282
R+ ++ C C GY G C+
Sbjct: 483 --RSVGTSYKCLCDPGYHGLYCE 503
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +1
Query: 61 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 525
Query: 235 NHTCDCPLGYAGASCQM 285
+ C C Y G C++
Sbjct: 526 GYECVCLAEYKGTHCEL 542
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 9/54 (16%)
Frame = +1
Query: 151 SPPPPVNPCSLHPCRNGGTC----KPDRN-----SWMNHTCDCPLGYAGASCQM 285
+P PC+ PCRNGG C +PD ++C CP G +GA+CQ+
Sbjct: 40 APLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQL 93
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 511 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 559
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
D +N TC C G+ G C + +
Sbjct: 560 SD---GLNGTCICAPGFTGEECDIDI 582
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/69 (27%), Positives = 31/69 (44%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C CP G +G+ C+ +PC+ +PC +G +S + C C GY
Sbjct: 79 SCTCPAGISGANCQL-----------VADPCASNPCHHGNCSSSSSSSSDGYLCICNEGY 127
Query: 265 AGASCQMPL 291
G +C+ L
Sbjct: 128 EGPNCEQAL 136
Score = 31.1 bits (67), Expect = 4.5
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Frame = +1
Query: 31 ASESCQ---CENGGSCSTESTNCICPPGYTGSYCETRIAS 141
AS C C + S S++ CIC GY G CE + S
Sbjct: 99 ASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPS 138
>AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.
Length = 2923
Score = 62.9 bits (146), Expect = 1e-09
Identities = 68/210 (32%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
P N C + C NGGTC N W +C+CPLG+ G SC E+ F G+ V
Sbjct: 1572 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSCAQ--EMANPQHFLGSSLVA 1626
Query: 337 LPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVVLEW 513
L S P ++L T DGVL QA L++ G V+L
Sbjct: 1627 WHGLSLP----ISQPWYLSLMFRTRQADGVLL-----QAITRGRSTITLQLREGHVMLSV 1677
Query: 514 DLGGGL--SSIVVDV-PINDGERHQVAARLHED---GHAWLSVD-GVDKSAPATGISNVM 672
+ G GL SS+ ++ NDG+ H L GHA LS D G ++ G
Sbjct: 1678 E-GTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHG 1736
Query: 673 NADSNIYIGGIPSWLNIHGYPGFIGCIENV 762
SNI +GGIP GF GC++ V
Sbjct: 1737 LHLSNITVGGIPGPAG-GVARGFRGCLQGV 1765
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1274 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1319
Query: 268 GASCQMPLELGQ 303
G C++ G+
Sbjct: 1320 GEHCEVSARSGR 1331
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
+S C CS + S +C C PGY G C N C L+PC + C
Sbjct: 1798 DSNPCPANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVC 1843
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ +TC+CP Y G C+ ++
Sbjct: 1844 TRKPSAPHGYTCECPPNYLGPYCETRID 1871
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 7/203 (3%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1334
Query: 184 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQMPLELGQSVGFNGNGYVELPASLLR 357
C+NGGTC N + CDCP G + CQ+ F + ++ R
Sbjct: 1335 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQVTTR-----SFPAHSFITFRGLRQR 1386
Query: 358 YDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
+ +AL+ T DG+L Y + D+ L + + V L + G +
Sbjct: 1387 FH------FTLALSFATKERDGLLLYNGRFN---EKHDFVALEVIQEQVQLTFSAGESTT 1437
Query: 535 SIVVDVP--INDGERHQVAARLH 597
++ VP ++DG+ H V + +
Sbjct: 1438 TVSPFVPGGVSDGQWHTVQLKYY 1460
Score = 35.1 bits (77), Expect = 0.28
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC C N W +++C C GY G +C
Sbjct: 1795 DPCDSNPCPANSYCS---NDWDSYSCSCDPGYYGDNC 1828
>AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix
receptor protein.
Length = 2923
Score = 62.9 bits (146), Expect = 1e-09
Identities = 68/210 (32%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
P N C + C NGGTC N W +C+CPLG+ G SC E+ F G+ V
Sbjct: 1572 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSCAQ--EMANPQHFLGSSLVA 1626
Query: 337 LPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVVLEW 513
L S P ++L T DGVL QA L++ G V+L
Sbjct: 1627 WHGLSLP----ISQPWYLSLMFRTRQADGVLL-----QAITRGRSTITLQLREGHVMLSV 1677
Query: 514 DLGGGL--SSIVVDV-PINDGERHQVAARLHED---GHAWLSVD-GVDKSAPATGISNVM 672
+ G GL SS+ ++ NDG+ H L GHA LS D G ++ G
Sbjct: 1678 E-GTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHG 1736
Query: 673 NADSNIYIGGIPSWLNIHGYPGFIGCIENV 762
SNI +GGIP GF GC++ V
Sbjct: 1737 LHLSNITVGGIPGPAG-GVARGFRGCLQGV 1765
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1274 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1319
Query: 268 GASCQMPLELGQ 303
G C++ G+
Sbjct: 1320 GEHCEVSARSGR 1331
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
+S C CS + S +C C PGY G C N C L+PC + C
Sbjct: 1798 DSNPCPANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVC 1843
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ +TC+CP Y G C+ ++
Sbjct: 1844 TRKPSAPHGYTCECPPNYLGPYCETRID 1871
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 7/203 (3%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1284 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1334
Query: 184 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQMPLELGQSVGFNGNGYVELPASLLR 357
C+NGGTC N + CDCP G + CQ+ F + ++ R
Sbjct: 1335 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQVTTR-----SFPAHSFITFRGLRQR 1386
Query: 358 YDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
+ +AL+ T DG+L Y + D+ L + + V L + G +
Sbjct: 1387 FH------FTLALSFATKERDGLLLYNGRFN---EKHDFVALEVIQEQVQLTFSAGESTT 1437
Query: 535 SIVVDVP--INDGERHQVAARLH 597
++ VP ++DG+ H V + +
Sbjct: 1438 TVSPFVPGGVSDGQWHTVQLKYY 1460
Score = 35.1 bits (77), Expect = 0.28
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC C N W +++C C GY G +C
Sbjct: 1795 DPCDSNPCPANSYCS---NDWDSYSCSCDPGYYGDNC 1828
>X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat
protein protein.
Length = 4590
Score = 62.5 bits (145), Expect = 2e-09
Identities = 62/211 (29%), Positives = 91/211 (43%), Gaps = 9/211 (4%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSW-MNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYV 333
PP + C PC G C D W HTC CP G G Q P S+ GN YV
Sbjct: 3790 PPVHHGCEDDPCPEGSECVSD--PWEEKHTCVCPSGRFG---QCP--GSSSMTLTGNSYV 3842
Query: 334 ELPASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEW 513
+ L + + L ++T+ V+ Y R DY +L I G + ++
Sbjct: 3843 KY--RLTENENKLEMKLTMRLRTYSTH-AVVMYAR-------GTDYSILEIHHGRLQYKF 3892
Query: 514 DLGGGLSSI-VVDVPINDGERHQVAARLHEDGHAWLSVDGV-DKSAPATGISNVMNADSN 687
D G G + V + +NDG+ H VA ++ +A L +D V S A G +N D+
Sbjct: 3893 DCGSGPGIVSVQSIQVNDGQWHAVALEVN-GNYARLVLDQVHTASGTAPGTLKTLNLDNY 3951
Query: 688 IYIGG-IPSWLNIHGYP-----GFIGCIENV 762
++ GG I HG GF GC++++
Sbjct: 3952 VFFGGHIRQQGTRHGRSPQVGNGFRGCMDSI 3982
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 6/93 (6%)
Frame = +1
Query: 25 IQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+ A+E C C+NGG C+ C C Y G++CE VNPCS +
Sbjct: 4013 LTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEIS-----------VNPCSSN 4061
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC GGTC D ++ C C Y G CQ+
Sbjct: 4062 PCLYGGTCVVDNGGFV---CQCRGLYTGQRCQL 4091
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+NGG+C S + C C G+ G C++ I + CS +PC +G C+
Sbjct: 4100 CKNGGTCFDSLDGAVCQCDSGFRGERCQSDI-----------DECSGNPCLHGALCE--- 4145
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N+ ++ C+C Y G C+
Sbjct: 4146 NTHGSYHCNCSHEYRGRHCE 4165
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C GG+C ++ C C YTG C+ +SP C PC+N
Sbjct: 4055 VNPCSSNPCLYGGTCVVDNGGFVCQCRGLYTGQRCQ-------LSPY-----CKDEPCKN 4102
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
GGTC +S C C G+ G CQ ++
Sbjct: 4103 GGTC---FDSLDGAVCQCDSGFRGERCQSDID 4131
>BC063620-1|AAH63620.1| 488|Homo sapiens AGRN protein protein.
Length = 488
Score = 62.5 bits (145), Expect = 2e-09
Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 15/215 (6%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL---ELG--QSVGFNGNG 327
P S HPC NG +C P +++ C CP G++G C+ L G ++ F+G
Sbjct: 260 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 316
Query: 328 YVELPASLLRYDE-LASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
+VE ++ ++ L SN ++L T VL G+A DY L I G +
Sbjct: 317 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVL---WSGKA-TERADYVALAIVDGHLQ 372
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNV----M 672
L ++LG + VP+N +V A E L V AP TG S + +
Sbjct: 373 LSYNLGSQPVVLRSTVPVNTNRWLRVVAH-REQREGSLQ---VGNEAPVTGSSPLGATQL 428
Query: 673 NADSNIYIGGIPSWLNIHGYP-----GFIGCIENV 762
+ D +++GG+P P GF+GC+ +V
Sbjct: 429 DTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDV 463
Score = 60.9 bits (141), Expect = 5e-09
Identities = 57/231 (24%), Positives = 86/231 (37%), Gaps = 9/231 (3%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-- 213
C G C +C CPPG G C +PC +PC C+
Sbjct: 1 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-----------KSPCQPNPCHGAAPCRVL 49
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS----VGFNGNGYVELPASLLRYDELASNP 381
P+ + C+CPLG G CQ S FNG ++EL +L
Sbjct: 50 PEGGA----QCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKM 105
Query: 382 AVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPIN 561
A+ + + G+L Y GQ +GD+ L + + +DLG G + I P+
Sbjct: 106 ALEVVFLARGPSGLLLY--NGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVT 163
Query: 562 DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
G +V+ + A DG + V+N +Y+GG P +
Sbjct: 164 LGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDF 214
Score = 31.9 bits (69), Expect = 2.6
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCE 126
C NG SC C+CP G++G +CE
Sbjct: 269 CLNGASCVPREAAYVCLCPGGFSGPHCE 296
>BC007649-1|AAH07649.1| 488|Homo sapiens AGRN protein protein.
Length = 488
Score = 62.5 bits (145), Expect = 2e-09
Identities = 61/215 (28%), Positives = 95/215 (44%), Gaps = 15/215 (6%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL---ELG--QSVGFNGNG 327
P S HPC NG +C P +++ C CP G++G C+ L G ++ F+G
Sbjct: 260 PCTRASGHPCLNGASCVPREAAYV---CLCPGGFSGPHCEKGLVEKSAGDVDTLAFDGRT 316
Query: 328 YVELPASLLRYDE-LASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVV 504
+VE ++ ++ L SN ++L T VL G+A DY L I G +
Sbjct: 317 FVEYLNAVTESEKALQSNHFELSLRTEATQGLVL---WSGKA-TERADYVALAIVDGHLQ 372
Query: 505 LEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNV----M 672
L ++LG + VP+N +V A E L V AP TG S + +
Sbjct: 373 LSYNLGSQPVVLRSTVPVNTNRWLRVVAH-REQREGSLQ---VGNEAPVTGSSPLGATQL 428
Query: 673 NADSNIYIGGIPSWLNIHGYP-----GFIGCIENV 762
+ D +++GG+P P GF+GC+ +V
Sbjct: 429 DTDGALWLGGLPELPVGPALPKAYGTGFVGCLRDV 463
Score = 60.9 bits (141), Expect = 5e-09
Identities = 57/231 (24%), Positives = 86/231 (37%), Gaps = 9/231 (3%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK-- 213
C G C +C CPPG G C +PC +PC C+
Sbjct: 1 CHGGAPCQNLEAGRFHCQCPPGRVGPTCADE-----------KSPCQPNPCHGAAPCRVL 49
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQS----VGFNGNGYVELPASLLRYDELASNP 381
P+ + C+CPLG G CQ S FNG ++EL +L
Sbjct: 50 PEGGA----QCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHTFARDLGEKM 105
Query: 382 AVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPIN 561
A+ + + G+L Y GQ +GD+ L + + +DLG G + I P+
Sbjct: 106 ALEVVFLARGPSGLLLY--NGQKTDGKGDFVSLALRDRRLEFRYDLGKGAAVIRSREPVT 163
Query: 562 DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
G +V+ + A DG + V+N +Y+GG P +
Sbjct: 164 LGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDF 214
Score = 31.9 bits (69), Expect = 2.6
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 2/28 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCE 126
C NG SC C+CP G++G +CE
Sbjct: 269 CLNGASCVPREAAYVCLCPGGFSGPHCE 296
>AY358892-1|AAQ89251.1| 723|Homo sapiens DLL1 protein.
Length = 723
Score = 62.5 bits (145), Expect = 2e-09
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + G I + C+NGGSC+ S +C CPPG+ G CE +
Sbjct: 322 GATCELG-IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT----------- 369
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSVGFNGNGYVEL 339
C+ PC NGG C + ++C CP+GY+G +C+ ++ S NG V+L
Sbjct: 370 CADGPCFNGGRCSDSPDG--GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL 423
Score = 62.1 bits (144), Expect = 2e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--RYVCECARGYGGPNCQFLL 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 220 RNSWMNHTCDCPLGYAGASCQM-PLELGQSVGFNGNGYVELP 342
NS ++C CP G+ G C++ + FNG + P
Sbjct: 347 ENS---YSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATC--TNTGQGS 311
Query: 238 HTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELPAS 348
+TC C GY GA+C++ + E S NG +L S
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENS 349
>AL359813-8|CAI23223.1| 377|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 377
Score = 62.5 bits (145), Expect = 2e-09
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTCK 213
C+NGG C + +C+C PG+ G CE + PC PCRNGG C+
Sbjct: 95 CQNGGQCMYDGGGEYHCVCLPGFHGRDCERK-----------AGPCEQAGSPCRNGGQCQ 143
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
D+ +N TC C +G+ GA C++ ++
Sbjct: 144 DDQGFALNFTCRCLVGFVGARCEVNVD 170
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 177 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 224
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP GY G +C++ L
Sbjct: 225 VH--DFDCLCPSGYGGKTCELVL 245
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 136 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 184
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N + +C CP G+AG C + L+
Sbjct: 185 DGINRF---SCLCPEGFAGRFCTINLD 208
Score = 34.7 bits (76), Expect = 0.37
Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 15/96 (15%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP--CSLH--------- 186
S C+ C +C C PG+ G +CE + P C H
Sbjct: 30 SSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWADEHIC 89
Query: 187 ----PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
PC+NGG C D + C C G+ G C+
Sbjct: 90 TTQSPCQNGGQCMYDGGG--EYHCVCLPGFHGRDCE 123
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 215 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 251
>AL078605-2|CAB89569.1| 723|Homo sapiens delta-like 1 (Drosophila)
protein.
Length = 723
Score = 62.5 bits (145), Expect = 2e-09
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + G I + C+NGGSC+ S +C CPPG+ G CE +
Sbjct: 322 GATCELG-IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT----------- 369
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSVGFNGNGYVEL 339
C+ PC NGG C + ++C CP+GY+G +C+ ++ S NG V+L
Sbjct: 370 CADGPCFNGGRCSDSPDG--GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL 423
Score = 62.1 bits (144), Expect = 2e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--RYVCECARGYGGPNCQFLL 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 220 RNSWMNHTCDCPLGYAGASCQM-PLELGQSVGFNGNGYVELP 342
NS ++C CP G+ G C++ + FNG + P
Sbjct: 347 ENS---YSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATC--TNTGQGS 311
Query: 238 HTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELPAS 348
+TC C GY GA+C++ + E S NG +L S
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENS 349
>AF222310-1|AAG09716.1| 723|Homo sapiens Delta1 protein.
Length = 723
Score = 62.5 bits (145), Expect = 2e-09
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + G I + C+NGGSC+ S +C CPPG+ G CE +
Sbjct: 322 GATCELG-IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT----------- 369
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSVGFNGNGYVEL 339
C+ PC NGG C + ++C CP+GY+G +C+ ++ S NG V+L
Sbjct: 370 CADGPCFNGGRCSDSPDG--GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL 423
Score = 62.1 bits (144), Expect = 2e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--GYVCECARGYGGPNCQFLL 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 220 RNSWMNHTCDCPLGYAGASCQM-PLELGQSVGFNGNGYVELP 342
NS ++C CP G+ G C++ + FNG + P
Sbjct: 347 ENS---YSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATC--TNTGQGS 311
Query: 238 HTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELPAS 348
+TC C GY GA+C++ + E S NG +L S
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENS 349
>AF196571-1|AAF05834.1| 723|Homo sapiens Delta-like-1 protein
protein.
Length = 723
Score = 62.5 bits (145), Expect = 2e-09
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + G I + C+NGGSC+ S +C CPPG+ G CE +
Sbjct: 322 GATCELG-IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT----------- 369
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSVGFNGNGYVEL 339
C+ PC NGG C + ++C CP+GY+G +C+ ++ S NG V+L
Sbjct: 370 CADGPCFNGGRCSDSPDG--GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL 423
Score = 59.7 bits (138), Expect = 1e-08
Identities = 31/86 (36%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ ++ C+C Y G +CQ L
Sbjct: 498 QRGHGYV---CECARSYGGPNCQFLL 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 220 RNSWMNHTCDCPLGYAGASCQM-PLELGQSVGFNGNGYVELP 342
NS ++C CP G+ G C++ + FNG + P
Sbjct: 347 ENS---YSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATC--TNTGQGS 311
Query: 238 HTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELPAS 348
+TC C GY GA+C++ + E S NG +L S
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENS 349
>AF003522-1|AAB61286.1| 723|Homo sapiens Delta protein.
Length = 723
Score = 62.5 bits (145), Expect = 2e-09
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + G I + C+NGGSC+ S +C CPPG+ G CE +
Sbjct: 322 GATCELG-IDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT----------- 369
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSVGFNGNGYVEL 339
C+ PC NGG C + ++C CP+GY+G +C+ ++ S NG V+L
Sbjct: 370 CADGPCFNGGRCSDSPDG--GYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL 423
Score = 62.1 bits (144), Expect = 2e-09
Identities = 33/86 (38%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C +C CPPGYTG C PV+ C PC NG TC
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA-----------PVSRCEHAPCHNGATCH 497
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+R + C+C GY G +CQ L
Sbjct: 498 -ERGH--GYVCECARGYGGPNCQFLL 520
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NG +C+ S C C PGYTG+ CE I + C PC+NGG+C
Sbjct: 298 CKNGATCTNTGQGSYTCSCRPGYTGATCELGI-----------DECDPSPCKNGGSCTDL 346
Query: 220 RNSWMNHTCDCPLGYAGASCQM-PLELGQSVGFNGNGYVELP 342
NS ++C CP G+ G C++ + FNG + P
Sbjct: 347 ENS---YSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSP 385
Score = 55.6 bits (128), Expect = 2e-07
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
I S C NG C ++ C C G++G +C+ V+ C+ PC N
Sbjct: 406 IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDN-----------VDDCASSPCAN 454
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
GGTC+ N + +C CP GY G +C P+
Sbjct: 455 GGTCRDGVNDF---SCTCPPGYTGRNCSAPV 482
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRNSWMN 237
G+C + C C G+ G +C + N C+ H PC+NG TC +
Sbjct: 266 GTCQ-QPWQCNCQEGWGGLFCNQDL-----------NYCTHHKPCKNGATC--TNTGQGS 311
Query: 238 HTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELPAS 348
+TC C GY GA+C++ + E S NG +L S
Sbjct: 312 YTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENS 349
>D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.
Length = 2854
Score = 62.1 bits (144), Expect = 2e-09
Identities = 68/210 (32%), Positives = 89/210 (42%), Gaps = 8/210 (3%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
P N C + C NGGTC N W +C+CPLG+ G SC E+ F G+ V
Sbjct: 1503 PAKKNVCDSNTCHNGGTCV---NQWDAFSCECPLGFGGKSCAQ--EMANPQHFLGSSLVA 1557
Query: 337 LPASLLRYDELASNPAVIALAVHTTN-DGVLAYQREGQAPPNEGDYFLLRIERGFVVLEW 513
L S P ++L T DGVL QA L++ G V+L
Sbjct: 1558 WHGLSLP----ISQPWHLSLMFRTRQADGVLL-----QAITRGRSTITLQLREGHVMLSV 1608
Query: 514 DLGGGL--SSIVVDV-PINDGERHQVAARLHED---GHAWLSVD-GVDKSAPATGISNVM 672
+ G GL SS+ ++ NDG+ H L GHA LS D G ++ G
Sbjct: 1609 E-GTGLQASSLRLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHG 1667
Query: 673 NADSNIYIGGIPSWLNIHGYPGFIGCIENV 762
SNI +GGIP GF GC++ V
Sbjct: 1668 LHLSNITVGGIPGPAG-GVARGFRGCLQGV 1696
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/72 (36%), Positives = 33/72 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+TG YCET V+ C PC G C R+ +TC C GY
Sbjct: 1205 CRCPPGFTGDYCETE-----------VDLCYSRPCGPHGRC---RSREGGYTCLCRDGYT 1250
Query: 268 GASCQMPLELGQ 303
G C++ G+
Sbjct: 1251 GEHCEVSARSGR 1262
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
+S C CS + S +C C PGY G C N C L+PC + C
Sbjct: 1729 DSNPCPANSYCSNDWDSYSCSCDPGYYGDNC--------------TNVCDLNPCEHQSVC 1774
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ +TC+CP Y G C+ ++
Sbjct: 1775 TRKPSAPHGYTCECPPNYLGPYCETRID 1802
Score = 42.3 bits (95), Expect = 0.002
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 7/203 (3%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
Y ++ S C G C + C+C GYTG +CE S C+
Sbjct: 1215 YCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARS---------GRCTP 1265
Query: 184 HPCRNGGTCKPDRNSWM-NHTCDCPLG-YAGASCQMPLELGQSVGFNGNGYVELPASLLR 357
C+NGGTC N + CDCP G + CQ+ F + ++ R
Sbjct: 1266 GVCKNGGTCV---NLLVGGFKCDCPSGDFEKPYCQVTTR-----SFPAHSFITFRGLRQR 1317
Query: 358 YDELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
+ +AL+ T DG+L Y + D+ L + + V L + G +
Sbjct: 1318 FH------FTLALSFATKERDGLLLYNGRFN---EKHDFVALEVIQEQVQLTFSAGESTT 1368
Query: 535 SIVVDVP--INDGERHQVAARLH 597
++ VP ++DG+ H V + +
Sbjct: 1369 TVSPFVPGGVSDGQWHTVQLKYY 1391
Score = 35.1 bits (77), Expect = 0.28
Identities = 13/37 (35%), Positives = 19/37 (51%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
+PC +PC C N W +++C C GY G +C
Sbjct: 1726 DPCDSNPCPANSYCS---NDWDSYSCSCDPGYYGDNC 1759
>AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein.
Length = 1282
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G + G + S C NGG+C C CPPG++G +CE ++P +P
Sbjct: 481 GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCE-------IAP----SP 529
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C PC NGGTC+ DR++ + C C GY G CQ ++ G
Sbjct: 530 CFRSPCVNGGTCE-DRDT--DFFCHCQAGYMGRRCQAEVDCG 568
Score = 60.5 bits (140), Expect = 6e-09
Identities = 35/109 (32%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C+NGG+C+ S C CP G+ G CET +PC C+
Sbjct: 180 DVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCET-----------AQSPCDTKECQ 228
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVEL 339
+GG C+ + S C C GY GA+C+M + + NG V+L
Sbjct: 229 HGGQCQVENGS---AVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDL 274
Score = 59.3 bits (137), Expect = 1e-08
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C +GGSC C+C GY G++CE + C HPCR
Sbjct: 622 EIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELER-----------DECRAHPCR 670
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG+C RN + C CP G+ G C+ ++
Sbjct: 671 NGGSC---RNLPGAYVCRCPAGFVGVHCETEVD 700
Score = 58.4 bits (135), Expect = 3e-08
Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +1
Query: 37 ESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
+S C NGGSC +S C CP G+ G +CE + +L CS PCRNGGTC
Sbjct: 415 DSDPCFNGGSCDAHDDSYTCECPRGFHGKHCE-KARPHL---------CSSGPCRNGGTC 464
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
K + + C CP + G C++
Sbjct: 465 K---EAGGEYHCSCPYRFTGRHCEI 486
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Frame = +1
Query: 49 CENGGSCSTE------STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG C + S C C G+TG C VN C+ PC+NGGTC
Sbjct: 147 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHL-----------DVNECASQPCQNGGTC 195
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
NS+ C CP G+ G +C+
Sbjct: 196 THGINSF---RCQCPAGFGGPTCE 216
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A +S C++GG C + C+CP + G +CET +PC PC
Sbjct: 698 EVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCET-----------VSDPCFSSPCG 746
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G C S H+C C +GY G C L
Sbjct: 747 GRGYCLASNGS---HSCTCKVGYTGEDCAKEL 775
Score = 51.6 bits (118), Expect = 3e-06
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ C NGGSC N C+C + G CET P + C PC
Sbjct: 256 DVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCET-------GDHPVPDACLSAPCH 308
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC ++ + C+CP G+ G C+
Sbjct: 309 NGGTCV---DADQGYVCECPEGFMGLDCR 334
Score = 51.6 bits (118), Expect = 3e-06
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSC + C CP G+ G +CET V+ C PC++GG C+
Sbjct: 669 CRNGGSCRNLPGAYVCRCPAGFVGVHCETE-----------VDACDSSPCQHGGRCESGG 717
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
+++ C CP + G C+ + S G GY
Sbjct: 718 GAYL---CVCPESFFGYHCETVSDPCFSSPCGGRGY 750
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 29/111 (26%)
Frame = +1
Query: 37 ESCQCENGGSC-STESTNCICPPGY---------------------TGSYCETRIASYLM 150
+ C+C NGG C +T C CP G+ G YC SYL
Sbjct: 339 DDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLC 398
Query: 151 SPPPPVN-------PCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N PC PC NGG+C +S +TC+CP G+ G C+
Sbjct: 399 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDS---YTCECPRGFHGKHCE 446
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 5/98 (5%)
Frame = +1
Query: 13 DRGDIQASESC---QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
+ GD ++C C NGG+C + + C CP G+ G C R+ + C
Sbjct: 292 ETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP----------DDC 341
Query: 178 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CRNGG C + C CPLG+ G C+ +
Sbjct: 342 E---CRNGGRCLGANTT----LCQCPLGFFGLLCEFEI 372
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 1180 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 1213
Score = 34.3 bits (75), Expect = 0.49
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 1185 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 1240
Score = 33.1 bits (72), Expect = 1.1
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Frame = +1
Query: 178 SLHPCRNGGTCKPD-RNSWMNHTCDCPLGYAGASCQM 285
+L PC NGG C D ++TC C G+ G C +
Sbjct: 143 ALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHL 179
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/192 (25%), Positives = 71/192 (36%), Gaps = 2/192 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI C +GG+C +C CP G+TG CE +N C PC+
Sbjct: 2160 DIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACER-----------DINECLQSPCK 2208
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELAS 375
NG C+ S+ C C GY G G+ N G+ EL S + + L
Sbjct: 2209 NGAICQNFPGSF---NCVCKTGYTGV-------FGKHCELNSYGFEEL--SYMEFPSLDP 2256
Query: 376 NPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVP 555
N I + T L + ++ L I + ++LG G +
Sbjct: 2257 NNNYIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYNLGSGTYKLTTMKK 2316
Query: 556 INDGERHQVAAR 591
++DG H V AR
Sbjct: 2317 VSDGHFHTVIAR 2328
Score = 50.4 bits (115), Expect = 7e-06
Identities = 23/66 (34%), Positives = 34/66 (51%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C P + C + +Y PP C+ HPC+NGG+C+P +S TC CP +
Sbjct: 2645 CASNPCWGDLLCINQWYAYRCVPP---GDCASHPCQNGGSCEPGLHS--GFTCSCPDSHT 2699
Query: 268 GASCQM 285
G +C+M
Sbjct: 2700 GRTCEM 2705
Score = 47.2 bits (107), Expect = 6e-05
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PGY GS+CE ++ C PC +GGTC N +C CP G+
Sbjct: 2146 CKCLPGYAGSWCEI-----------DIDECLPSPCHSGGTC---HNLVGGFSCSCPDGFT 2191
Query: 268 GASCQMPL-ELGQSVGFNGNGYVELPAS 348
G +C+ + E QS NG P S
Sbjct: 2192 GRACERDINECLQSPCKNGAICQNFPGS 2219
Score = 33.5 bits (73), Expect = 0.85
Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 3/33 (9%)
Frame = +1
Query: 49 CENGGSCST---ESTNCICPPGYTGSYCETRIA 138
C+NGGSC C CP +TG CE +A
Sbjct: 2676 CQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVA 2708
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 214
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + + C C G+ G +C++ ++
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVD 238
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1103
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+M C+C GY G +C+
Sbjct: 1104 GGYM---CECLPGYNGDNCE 1120
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 431 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 479
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELP 342
NGG CK N + +C CP G++G++CQ+ + E + NG V+ P
Sbjct: 480 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP 526
Score = 57.6 bits (133), Expect = 5e-08
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 784
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C+ C CP G+ G CQ ++
Sbjct: 785 RCESAPGQL--PVCSCPQGWQGPRCQQDVD 812
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 213
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 291
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
N+ H+C C G+ G SC + + +V F+G
Sbjct: 292 --FNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHG 326
Score = 54.4 bits (125), Expect = 4e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1067
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
H C CP G G+ C+ ++
Sbjct: 1068 ---HYCVCPEGRTGSHCEQEVD 1086
Score = 53.2 bits (122), Expect = 1e-06
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 512
Query: 181 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 279
PCRNG C +PD + C C G+ G C
Sbjct: 513 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 542
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 207
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 125 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 173
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMP 288
C N+ + C CP GY G C+ P
Sbjct: 174 C---LNTPGSFRCQCPAGYTGPLCENP 197
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G + D+ C NGG+C S +C+C PGYTG++C+ +P
Sbjct: 917 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADP 965
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC +GG C + C C + G CQ
Sbjct: 966 CLSRPCLHGGVCSAAHPGF---RCTCLESFTGPQCQ 998
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLHPCRNGGTCKP 216
QC G C + C CPPG +G C S+ SPP N C+ PC +GG+C+P
Sbjct: 1297 QCPVGVPCQQTPRGPRCACPPGLSGPSCR----SFPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 217 DRNSWMNHTCDCPLGYAGASCQMP 288
+ C C G+ G C+ P
Sbjct: 1353 APLAPF-FRCACAQGWTGPRCEAP 1375
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +1
Query: 49 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 96
Query: 220 -RNSWMNHTCDCPLGYAGASCQMP 288
+C CP G+ G C +P
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLP 120
Score = 50.4 bits (115), Expect = 7e-06
Identities = 37/108 (34%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C NGGSC S +C C PG+ G C V+ C +PC
Sbjct: 849 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC- 896
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
GTC S+ TC CP GY G C+ L + S FNG V+
Sbjct: 897 GPGTCTDHVASF---TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 941
Score = 50.4 bits (115), Expect = 7e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 899 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 946
Query: 235 NHTCDCPLGYAGASCQ 282
+C C GY GA CQ
Sbjct: 947 --SCLCRPGYTGAHCQ 960
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +1
Query: 79 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 258
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 565 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 610
Query: 259 GYAGASCQMPLE 294
G G +C++ ++
Sbjct: 611 GTTGVNCEVNID 622
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 254
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N+ + C CP + G C
Sbjct: 255 VNT---YNCQCPPEWTGQFC 271
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 449
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
TC C G+ G C++ ++ QS
Sbjct: 450 IG--QFTCICMAGFTGTYCEVDIDECQS 475
Score = 48.0 bits (109), Expect = 4e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 718 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 765
Query: 268 GASCQM 285
G C++
Sbjct: 766 GRQCEL 771
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1177
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ GTC + C CP GY G C+
Sbjct: 1178 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1203
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1138
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ + C CP G G C++
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEI 1159
Score = 44.4 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 192
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 402
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G C + S++ C C GY G C+
Sbjct: 403 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 429
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G C+ S +C C GYTG C+ I N C +PC NGG+C+
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-----------NDCDPNPCLNGGSCQDGV 868
Query: 223 NSWMNHTCDCPLGYAGASC 279
S+ +C C G+AG C
Sbjct: 869 GSF---SCSCLPGFAGPRC 884
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 12/105 (11%)
Frame = +1
Query: 40 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 358
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLELGQSVGFN 318
PC C D N C CP G+ G +C ++ S+G N
Sbjct: 359 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD-ECSIGAN 400
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 261
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1232 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
Query: 262 YAGASCQ 282
+ G C+
Sbjct: 1281 FWGPRCE 1287
Score = 40.7 bits (91), Expect = 0.006
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 140
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
C CP GY G SC+ ++
Sbjct: 141 --RFLCSCPPGYQGRSCRSDVD 160
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 642 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 687
Query: 265 AGASCQMP 288
C P
Sbjct: 688 LPPLCLPP 695
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 1017
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
C CP G++G C +
Sbjct: 1018 ---TGAYCLCPPGWSGRLCDI 1035
Score = 39.9 bits (89), Expect = 0.010
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 705
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ G C + C C G++G C L
Sbjct: 706 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 733
Score = 38.3 bits (85), Expect = 0.030
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R + Q E S C +GG C + C CP G TG CE I
Sbjct: 573 GYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI----------- 621
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C+ +PC G C+ N + C C G+ G C + +
Sbjct: 622 DDCASNPC-TFGVCRDGIN---RYDCVCQPGFTGPLCNVEI 658
Score = 37.1 bits (82), Expect = 0.069
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1223
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
++ C C G++G CQ L
Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVL 1247
Score = 34.7 bits (76), Expect = 0.37
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
CE+GG C + C CP G+ G C+ + + P P P H G C
Sbjct: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPAPCGP---H-----GICTNL 829
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
S+ +C C GY G SC +
Sbjct: 830 AGSF---SCTCHGGYTGPSCDQDI 850
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Frame = +1
Query: 145 LMSPPPPVNPC-SLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM--PLELGQSV 309
L P PC PC NGG C P R + C CP G+ G CQ+ P G
Sbjct: 33 LAGPGAAAPPCLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHSGPCA 88
Query: 310 G 312
G
Sbjct: 89 G 89
Score = 33.1 bits (72), Expect = 1.1
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 8/86 (9%)
Frame = +1
Query: 49 CENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C +GGSC C C G+TG CE A+ +S P + R C
Sbjct: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1403
Query: 217 DRNS----WMNHTCDCPLGYAGASCQ 282
+ NS W C +G C+
Sbjct: 1404 ECNSPGCGWDGGDCSLSVGDPWRQCE 1429
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 214
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + + C C G+ G +C++ ++
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVD 238
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1103
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+M C+C GY G +C+
Sbjct: 1104 GGYM---CECLPGYNGDNCE 1120
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 431 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 479
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELP 342
NGG CK N + +C CP G++G++CQ+ + E + NG V+ P
Sbjct: 480 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP 526
Score = 57.6 bits (133), Expect = 5e-08
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 784
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C+ C CP G+ G CQ ++
Sbjct: 785 RCESAPGQL--PVCSCPQGWQGPRCQQDVD 812
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 213
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 291
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
N+ H+C C G+ G SC + + +V F+G
Sbjct: 292 --FNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHG 326
Score = 54.4 bits (125), Expect = 4e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1067
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
H C CP G G+ C+ ++
Sbjct: 1068 ---HYCVCPEGRTGSHCEQEVD 1086
Score = 53.2 bits (122), Expect = 1e-06
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 512
Query: 181 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 279
PCRNG C +PD + C C G+ G C
Sbjct: 513 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 542
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 207
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 125 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 173
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMP 288
C N+ + C CP GY G C+ P
Sbjct: 174 C---LNTPGSFRCQCPAGYTGPLCENP 197
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G + D+ C NGG+C S +C+C PGYTG++C+ +P
Sbjct: 917 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADP 965
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC +GG C + C C + G CQ
Sbjct: 966 CLSRPCLHGGVCSAAHPGF---RCTCLESFTGPQCQ 998
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLHPCRNGGTCKP 216
QC G C + C CPPG +G C S+ SPP N C+ PC +GG+C+P
Sbjct: 1297 QCPVGVPCQQTPRGPRCACPPGLSGPSCR----SFPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 217 DRNSWMNHTCDCPLGYAGASCQMP 288
+ C C G+ G C+ P
Sbjct: 1353 APLAPF-FRCACAQGWTGPRCEAP 1375
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +1
Query: 49 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 96
Query: 220 -RNSWMNHTCDCPLGYAGASCQMP 288
+C CP G+ G C +P
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLP 120
Score = 50.4 bits (115), Expect = 7e-06
Identities = 37/108 (34%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C NGGSC S +C C PG+ G C V+ C +PC
Sbjct: 849 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC- 896
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
GTC S+ TC CP GY G C+ L + S FNG V+
Sbjct: 897 GPGTCTDHVASF---TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 941
Score = 50.4 bits (115), Expect = 7e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 899 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 946
Query: 235 NHTCDCPLGYAGASCQ 282
+C C GY GA CQ
Sbjct: 947 --SCLCRPGYTGAHCQ 960
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +1
Query: 79 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 258
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 565 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 610
Query: 259 GYAGASCQMPLE 294
G G +C++ ++
Sbjct: 611 GTTGVNCEVNID 622
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 254
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N+ + C CP + G C
Sbjct: 255 VNT---YNCQCPPEWTGQFC 271
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 449
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
TC C G+ G C++ ++ QS
Sbjct: 450 IG--QFTCICMAGFTGTYCEVDIDECQS 475
Score = 48.0 bits (109), Expect = 4e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 718 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 765
Query: 268 GASCQM 285
G C++
Sbjct: 766 GRQCEL 771
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1177
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ GTC + C CP GY G C+
Sbjct: 1178 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1203
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1138
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ + C CP G G C++
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEI 1159
Score = 44.4 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 192
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 402
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G C + S++ C C GY G C+
Sbjct: 403 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 429
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G C+ S +C C GYTG C+ I N C +PC NGG+C+
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-----------NDCDPNPCLNGGSCQDGV 868
Query: 223 NSWMNHTCDCPLGYAGASC 279
S+ +C C G+AG C
Sbjct: 869 GSF---SCSCLPGFAGPRC 884
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 12/105 (11%)
Frame = +1
Query: 40 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 299 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 358
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLELGQSVGFN 318
PC C D N C CP G+ G +C ++ S+G N
Sbjct: 359 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD-ECSIGAN 400
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 261
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1232 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
Query: 262 YAGASCQ 282
+ G C+
Sbjct: 1281 FWGPRCE 1287
Score = 40.7 bits (91), Expect = 0.006
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 140
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
C CP GY G SC+ ++
Sbjct: 141 --RFLCSCPPGYQGRSCRSDVD 160
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 642 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 687
Query: 265 AGASCQMP 288
C P
Sbjct: 688 LPPLCLPP 695
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 1017
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
C CP G++G C +
Sbjct: 1018 ---TGAYCLCPPGWSGRLCDI 1035
Score = 39.9 bits (89), Expect = 0.010
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 705
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ G C + C C G++G C L
Sbjct: 706 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 733
Score = 38.3 bits (85), Expect = 0.030
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R + Q E S C +GG C + C CP G TG CE I
Sbjct: 573 GYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI----------- 621
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C+ +PC G C+ N + C C G+ G C + +
Sbjct: 622 DDCASNPC-TFGVCRDGIN---RYDCVCQPGFTGPLCNVEI 658
Score = 37.1 bits (82), Expect = 0.069
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1223
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
++ C C G++G CQ L
Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVL 1247
Score = 34.7 bits (76), Expect = 0.37
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
CE+GG C + C CP G+ G C+ + + P P P H G C
Sbjct: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPAPCGP---H-----GICTNL 829
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
S+ +C C GY G SC +
Sbjct: 830 AGSF---SCTCHGGYTGPSCDQDI 850
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Frame = +1
Query: 145 LMSPPPPVNPC-SLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM--PLELGQSV 309
L P PC PC NGG C P R + C CP G+ G CQ+ P G
Sbjct: 33 LAGPGAAAPPCLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHSGPCA 88
Query: 310 G 312
G
Sbjct: 89 G 89
Score = 33.1 bits (72), Expect = 1.1
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 8/86 (9%)
Frame = +1
Query: 49 CENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C +GGSC C C G+TG CE A+ +S P + R C
Sbjct: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1403
Query: 217 DRNS----WMNHTCDCPLGYAGASCQ 282
+ NS W C +G C+
Sbjct: 1404 ECNSPGCGWDGGDCSLSVGDPWRQCE 1429
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 128 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 174
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + + C C G+ G +C++ ++
Sbjct: 175 SGDLTYDCACLPGFEGQNCEVNVD 198
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1015 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1063
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+M C+C GY G +C+
Sbjct: 1064 GGYM---CECLPGYNGDNCE 1080
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 391 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 439
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELP 342
NGG CK N + +C CP G++G++CQ+ + E + NG V+ P
Sbjct: 440 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP 486
Score = 57.6 bits (133), Expect = 5e-08
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 697 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 744
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C+ C CP G+ G CQ ++
Sbjct: 745 RCESAPGQL--PVCSCPQGWQGPRCQQDVD 772
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 213
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 204 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 251
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
N+ H+C C G+ G SC + + +V F+G
Sbjct: 252 --FNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHG 286
Score = 54.4 bits (125), Expect = 4e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 969 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1027
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
H C CP G G+ C+ ++
Sbjct: 1028 ---HYCVCPEGRTGSHCEQEVD 1046
Score = 53.2 bits (122), Expect = 1e-06
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 424 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 472
Query: 181 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 279
PCRNG C +PD + C C G+ G C
Sbjct: 473 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 502
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 207
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 85 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 133
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMP 288
C N+ + C CP GY G C+ P
Sbjct: 134 C---LNTPGSFRCQCPAGYTGPLCENP 157
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G + D+ C NGG+C S +C+C PGYTG++C+ +P
Sbjct: 877 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADP 925
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC +GG C + C C + G CQ
Sbjct: 926 CLSRPCLHGGVCSAAHPGF---RCTCLESFTGPQCQ 958
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLHPCRNGGTCKP 216
QC G C + C CPPG +G C S+ SPP N C+ PC +GG+C+P
Sbjct: 1257 QCPVGVPCQQTPRGPRCACPPGLSGPSCR----SFPGSPPGASNASCAAAPCLHGGSCRP 1312
Query: 217 DRNSWMNHTCDCPLGYAGASCQMP 288
+ C C G+ G C+ P
Sbjct: 1313 APLAPF-FRCACAQGWTGPRCEAP 1335
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +1
Query: 49 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 9 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 56
Query: 220 -RNSWMNHTCDCPLGYAGASCQMP 288
+C CP G+ G C +P
Sbjct: 57 VVAGTARFSCRCPRGFRGPDCSLP 80
Score = 50.4 bits (115), Expect = 7e-06
Identities = 37/108 (34%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI + C NGGSC S +C C PG+ G C V+ C +PC
Sbjct: 809 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC- 856
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
GTC S+ TC CP GY G C+ L + S FNG V+
Sbjct: 857 GPGTCTDHVASF---TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 901
Score = 50.4 bits (115), Expect = 7e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 859 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 906
Query: 235 NHTCDCPLGYAGASCQ 282
+C C GY GA CQ
Sbjct: 907 --SCLCRPGYTGAHCQ 920
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +1
Query: 79 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 258
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 525 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 570
Query: 259 GYAGASCQMPLE 294
G G +C++ ++
Sbjct: 571 GTTGVNCEVNID 582
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 166 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 214
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N+ + C CP + G C
Sbjct: 215 VNT---YNCQCPPEWTGQFC 231
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 362 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 409
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
TC C G+ G C++ ++ QS
Sbjct: 410 IG--QFTCICMAGFTGTYCEVDIDECQS 435
Score = 48.0 bits (109), Expect = 4e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 678 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 725
Query: 268 GASCQM 285
G C++
Sbjct: 726 GRQCEL 731
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1082 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1137
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ GTC + C CP GY G C+
Sbjct: 1138 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1163
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1053 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1098
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ + C CP G G C++
Sbjct: 1099 DLVARYLCSCPPGTLGVLCEI 1119
Score = 44.4 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 192
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 314 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 362
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G C + S++ C C GY G C+
Sbjct: 363 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 389
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G C+ S +C C GYTG C+ I N C +PC NGG+C+
Sbjct: 780 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-----------NDCDPNPCLNGGSCQDGV 828
Query: 223 NSWMNHTCDCPLGYAGASC 279
S+ +C C G+AG C
Sbjct: 829 GSF---SCSCLPGFAGPRC 844
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 12/105 (11%)
Frame = +1
Query: 40 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 259 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 318
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLELGQSVGFN 318
PC C D N C CP G+ G +C ++ S+G N
Sbjct: 319 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD-ECSIGAN 360
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 261
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1192 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1240
Query: 262 YAGASCQ 282
+ G C+
Sbjct: 1241 FWGPRCE 1247
Score = 40.7 bits (91), Expect = 0.006
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 53 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 100
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
C CP GY G SC+ ++
Sbjct: 101 --RFLCSCPPGYQGRSCRSDVD 120
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 602 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 647
Query: 265 AGASCQMP 288
C P
Sbjct: 648 LPPLCLPP 655
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 931 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 977
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
C CP G++G C +
Sbjct: 978 ---TGAYCLCPPGWSGRLCDI 995
Score = 39.9 bits (89), Expect = 0.010
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 617 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 665
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ G C + C C G++G C L
Sbjct: 666 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 693
Score = 38.3 bits (85), Expect = 0.030
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R + Q E S C +GG C + C CP G TG CE I
Sbjct: 533 GYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI----------- 581
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C+ +PC G C+ N + C C G+ G C + +
Sbjct: 582 DDCASNPC-TFGVCRDGIN---RYDCVCQPGFTGPLCNVEI 618
Score = 37.1 bits (82), Expect = 0.069
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1135 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1183
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
++ C C G++G CQ L
Sbjct: 1184 QDPGGGFRCLCHAGFSGPRCQTVL 1207
Score = 34.7 bits (76), Expect = 0.37
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
CE+GG C + C CP G+ G C+ + + P P P H G C
Sbjct: 740 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPAPCGP---H-----GICTNL 789
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
S+ +C C GY G SC +
Sbjct: 790 AGSF---SCTCHGGYTGPSCDQDI 810
Score = 33.1 bits (72), Expect = 1.1
Identities = 23/86 (26%), Positives = 31/86 (36%), Gaps = 8/86 (9%)
Frame = +1
Query: 49 CENGGSCSTEST----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C +GGSC C C G+TG CE A+ +S P + R C
Sbjct: 1304 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1363
Query: 217 DRNS----WMNHTCDCPLGYAGASCQ 282
+ NS W C +G C+
Sbjct: 1364 ECNSPGCGWDGGDCSLSVGDPWRQCE 1389
Score = 32.3 bits (70), Expect = 2.0
Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 4/46 (8%)
Frame = +1
Query: 187 PCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM--PLELGQSVG 312
PC NGG C P R + C CP G+ G CQ+ P G G
Sbjct: 8 PCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHSGPCAG 49
>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
protein.
Length = 1289
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG+C + S C CP GYTG CE P PC+ PCRNGGTC+ +
Sbjct: 171 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN-----------PAVPCAPSPCRNGGTCR--Q 217
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ + + C C G+ G +C++ ++
Sbjct: 218 SGDLTYDCACLPGFEGQNCEVNVD 241
Score = 61.3 bits (142), Expect = 4e-09
Identities = 30/80 (37%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C+ GG C E ++ C+CP G TGS+CE V+PC PC++GGTC+
Sbjct: 1006 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQE-----------VDPCLAQPCQHGGTCRGYM 1054
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+M C+C GY G +C+
Sbjct: 1055 GGYM---CECLPGYNGDNCE 1071
Score = 59.7 bits (138), Expect = 1e-08
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C N +C CIC G+TG+YCE ++ C PC
Sbjct: 434 DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-----------DIDECQSSPCV 482
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELP 342
NGG CK N + +C CP G++G++CQ+ + E + NG V+ P
Sbjct: 483 NGGVCKDRVNGF---SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP 529
Score = 56.4 bits (130), Expect = 1e-07
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Frame = +1
Query: 46 QCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 213
+C NGG+C + NC CPP +TG +C V+ C L P C NGGTC
Sbjct: 247 RCLNGGTCVDGVNTYNCQCPPEWTGQFC-----------TEDVDECQLQPNACHNGGTC- 294
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNG 321
N+ H+C C G+ G SC + + +V F+G
Sbjct: 295 --FNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHG 329
Score = 54.4 bits (125), Expect = 4e-07
Identities = 25/82 (30%), Positives = 39/82 (47%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C C+CPPG++G C+ R + + C+ GG C + +S
Sbjct: 960 CQNGGRCVQTGAYCLCPPGWSGRLCDIR-SLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1018
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
H C CP G G+ C+ ++
Sbjct: 1019 ---HYCVCPEGRTGSHCEQEVD 1037
Score = 53.2 bits (122), Expect = 1e-06
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY DI +S C NGG C +C CP G++GS C+ V+ C+
Sbjct: 467 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL-----------DVDECA 515
Query: 181 LHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASC 279
PCRNG C +PD + C C G+ G C
Sbjct: 516 STPCRNGAKCVDQPD-----GYECRCAEGFEGTLC 545
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGT 207
S C +G CS C CPPGY G C + V+ C + PCR+GGT
Sbjct: 128 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-----------DVDECRVGEPCRHGGT 176
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMP 288
C N+ + C CP GY G C+ P
Sbjct: 177 C---LNTPGSFRCQCPAGYTGPLCENP 200
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G + D+ C NGG+C S +C+C PGYTG++C+ +P
Sbjct: 868 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE-----------ADP 916
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
C PC +GG C + C C + G CQ
Sbjct: 917 CLSRPCLHGGVCSAAHPGF---RCTCLESFTGPQCQ 949
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/91 (34%), Positives = 42/91 (46%), Gaps = 7/91 (7%)
Frame = +1
Query: 31 ASESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A ES C GG+CS++ +C CPPG G CE ++PC+ +PC +GG
Sbjct: 740 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL------------LSPCTPNPCEHGG 787
Query: 205 TCKPDRNSWMNHTCDCPLGYA-----GASCQ 282
C+ C CP G+ G SCQ
Sbjct: 788 RCESAPGQL--PVCSCPQGWQDPCLNGGSCQ 816
Score = 50.4 bits (115), Expect = 7e-06
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 4/84 (4%)
Frame = +1
Query: 49 CENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C+ + C+CPPG+ G C+ +PC PC G C+
Sbjct: 52 CANGGRCTQLPSREAACLCPPGWVGERCQLE------------DPCHSGPCAGRGVCQSS 99
Query: 220 -RNSWMNHTCDCPLGYAGASCQMP 288
+C CP G+ G C +P
Sbjct: 100 VVAGTARFSCRCPRGFRGPDCSLP 123
Score = 50.4 bits (115), Expect = 7e-06
Identities = 30/76 (39%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C+ S C CPPGY G +CE + CS C NGGTC NS+
Sbjct: 850 GTCTDHVASFTCTCPPGYGGFHCEQDLPD-----------CSPSSCFNGGTCVDGVNSF- 897
Query: 235 NHTCDCPLGYAGASCQ 282
+C C GY GA CQ
Sbjct: 898 --SCLCRPGYTGAHCQ 911
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +1
Query: 79 STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL 258
S +C C PGYTG+ CE++ V+ C PCR+GG C + ++ C CP
Sbjct: 568 SFSCACAPGYTGTRCESQ-----------VDECRSQPCRHGGKCLDLVDKYL---CRCPS 613
Query: 259 GYAGASCQMPLE 294
G G +C++ ++
Sbjct: 614 GTTGVNCEVNID 625
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSC--STEST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S + T +C C PG+ G CE V+ C H C NGGTC
Sbjct: 209 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVN-----------VDDCPGHRCLNGGTCVDG 257
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N+ + C CP + G C
Sbjct: 258 VNT---YNCQCPPEWTGQFC 274
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/99 (35%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSC S +C C PG+ G C V+ C +PC GTC
Sbjct: 809 CLNGGSCQDGVGSFSCSCLPGFAGPRCAR-----------DVDECLSNPC-GPGTCTDHV 856
Query: 223 NSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
S+ TC CP GY G C+ L + S FNG V+
Sbjct: 857 ASF---TCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 892
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC-STE-STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+ G C +T+ S C C GYTG CET VN C PCRN TC DR
Sbjct: 405 CEHLGRCVNTQGSFLCQCGRGYTGPRCET-----------DVNECLSGPCRNQATCL-DR 452
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
TC C G+ G C++ ++ QS
Sbjct: 453 IG--QFTCICMAGFTGTYCEVDIDECQS 478
Score = 48.0 bits (109), Expect = 4e-05
Identities = 23/66 (34%), Positives = 30/66 (45%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C+C PG++G C +A + C PCR GGTC D M C CP G
Sbjct: 721 CVCEPGWSGPRCSQSLAR---------DACESQPCRAGGTCSSD---GMGFHCTCPPGVQ 768
Query: 268 GASCQM 285
G C++
Sbjct: 769 GRQCEL 774
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ S C++GGSC C CPPG G CE I P PP++ S C
Sbjct: 1073 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGPPLD--SGPRCL 1128
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ GTC + C CP GY G C+
Sbjct: 1129 HNGTCVDLVGGF---RCTCPPGYTGLRCE 1154
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C C C PGY G CE V+ C+ PC++GG+C
Sbjct: 1044 CQHGGTCRGYMGGYMCECLPGYNGDNCE-----------DDVDECASQPCQHGGSC---I 1089
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ + C CP G G C++
Sbjct: 1090 DLVARYLCSCPPGTLGVLCEI 1110
Score = 44.4 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPC 192
A S C C T N C CPPG+TG C+ V+ CS+ +PC
Sbjct: 357 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD-----------QDVDECSIGANPC 405
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ G C + S++ C C GY G C+
Sbjct: 406 EHLGRCVNTQGSFL---CQCGRGYTGPRCE 432
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 12/105 (11%)
Frame = +1
Query: 40 SCQCENGG---SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPV--------NPCSLH 186
SC C NG SCS +C + G+ C R+AS+ + P + C +
Sbjct: 302 SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSN 361
Query: 187 PCRNGGTCKPDRNSWMNHT-CDCPLGYAGASCQMPLELGQSVGFN 318
PC C D N C CP G+ G +C ++ S+G N
Sbjct: 362 PCHEDAIC--DTNPVNGRAICTCPPGFTGGACDQDVD-ECSIGAN 403
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD--RNSWMNHTCDCPLG 261
C+C G++G C+T ++ PC PC++GG C+P + TC C
Sbjct: 1183 CLCHAGFSGPRCQTVLS-----------PCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1231
Query: 262 YAGASCQ 282
+ G C+
Sbjct: 1232 FWGPRCE 1238
Score = 40.7 bits (91), Expect = 0.006
Identities = 24/82 (29%), Positives = 34/82 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C++ T +C CP G+ G C S P +PC PC +G C +
Sbjct: 96 CQSSVVAGTARFSCRCPRGFRGPDC---------SLP---DPCLSSPCAHGARCSVGPDG 143
Query: 229 WMNHTCDCPLGYAGASCQMPLE 294
C CP GY G SC+ ++
Sbjct: 144 --RFLCSCPPGYQGRSCRSDVD 163
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/68 (32%), Positives = 28/68 (41%)
Frame = +1
Query: 85 NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
+C+C PG+TG C I N C+ PC GG+C N + C CP G
Sbjct: 645 DCVCQPGFTGPLCNVEI-----------NECASSPCGEGGSCVDGENGF---RCLCPPGS 690
Query: 265 AGASCQMP 288
C P
Sbjct: 691 LPPLCLPP 698
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C +GG CS C C +TG C+T V+ CS PC+NGG C
Sbjct: 922 CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-----------VDWCSRQPCQNGGRCVQ-- 968
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
C CP G++G C +
Sbjct: 969 ---TGAYCLCPPGWSGRLCDI 986
Score = 39.9 bits (89), Expect = 0.010
Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C GGSC C+CPPG C PP +PC+ PC
Sbjct: 660 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL-----------PPSHPCAHEPCS 708
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ G C + C C G++G C L
Sbjct: 709 H-GICYDAPGGF---RCVCEPGWSGPRCSQSL 736
Score = 38.3 bits (85), Expect = 0.030
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 4/101 (3%)
Frame = +1
Query: 1 GNTYDRGDIQASE--SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPV 168
G T R + Q E S C +GG C + C CP G TG CE I
Sbjct: 576 GYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI----------- 624
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C+ +PC G C+ N + C C G+ G C + +
Sbjct: 625 DDCASNPC-TFGVCRDGIN---RYDCVCQPGFTGPLCNVEI 661
Score = 37.1 bits (82), Expect = 0.069
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
+C + G+C C CPPGYTG CE +N C C T
Sbjct: 1126 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-----------DINECRSGACHAAHTRDCL 1174
Query: 220 RNSWMNHTCDCPLGYAGASCQMPL 291
++ C C G++G CQ L
Sbjct: 1175 QDPGGGFRCLCHAGFSGPRCQTVL 1198
Score = 33.9 bits (74), Expect = 0.64
Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Frame = +1
Query: 145 LMSPPPPVNPC-SLHPCRNGGTCK--PDRNSWMNHTCDCPLGYAGASCQM--PLELGQSV 309
L P PC PC NGG C P R + C CP G+ G CQ+ P G
Sbjct: 36 LAGPGAAAPPCLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHSGPCA 91
Query: 310 G 312
G
Sbjct: 92 G 92
>AC008273-1|AAF19247.2| 291|Homo sapiens unknown protein.
Length = 291
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 10/107 (9%)
Frame = +1
Query: 37 ESCQ---CENGGSC-----STESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
++CQ C+N SC + +N C+C PGYTG C+++I + C L
Sbjct: 68 DACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKI-----------DYCILD 116
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
PCRNG TC +S TC CP GY G++C+ ++ S NG
Sbjct: 117 PCRNGATC---ISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNG 160
Score = 58.4 bits (135), Expect = 3e-08
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C S C CP GY GS CE + V+PC+ PC+N GTC D
Sbjct: 118 CRNGATCISSLSGFTCQCPEGYFGSACEEK-----------VDPCASSPCQNNGTCYVD- 165
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ TC+C G+ G +C
Sbjct: 166 --GVHFTCNCSPGFTGPTC 182
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST---EST-NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
G+ A++ +C G C+T E+T +C C Y G++CE + C
Sbjct: 27 GESHAND-LECSGKGKCTTKPSEATFSCTCEEQYVGTFCE------------EYDACQRK 73
Query: 187 PCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
PC+N +C ++ N TC C GY G CQ ++
Sbjct: 74 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 111
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+N G+C + + C C PG+TG C I + C+L PC + GTC
Sbjct: 153 SSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLI-----------DFCALSPCAH-GTC- 199
Query: 214 PDRNSWMNHTCDCPLGYAGASCQ 282
R+ ++ C C GY G C+
Sbjct: 200 --RSVGTSYKCLCDPGYHGLYCE 220
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%)
Frame = +1
Query: 61 GSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+C + T+ C+C PGY G YCE N C PC N TC+ N
Sbjct: 197 GTCRSVGTSYKCLCDPGYHGLYCEEE-----------YNECLSAPCLNAATCRDLVN--- 242
Query: 235 NHTCDCPLGYAGASCQM 285
+ C C Y G C++
Sbjct: 243 GYECVCLAEYKGTHCEL 259
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 2/77 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N +C C+C Y G++CE +PC+ C NG TC
Sbjct: 228 SAPCLNAATCRDLVNGYECVCLAEYKGTHCELY-----------KDPCANVSCLNGATCD 276
Query: 214 PDRNSWMNHTCDCPLGY 264
D +N TC C G+
Sbjct: 277 SD---GLNGTCICAPGF 290
Score = 30.3 bits (65), Expect = 7.9
Identities = 11/23 (47%), Positives = 15/23 (65%), Gaps = 2/23 (8%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYT 111
C NG +C ++ N CIC PG+T
Sbjct: 269 CLNGATCDSDGLNGTCICAPGFT 291
>U70313-1|AAC02649.1| 125|Homo sapiens integrin binding protein
Del-1 protein.
Length = 125
Score = 60.5 bits (140), Expect = 6e-09
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
+ +GDI + CENGG C + S +C CP G+T C + + V PC
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVE---------VGPC 68
Query: 178 SLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 282
+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 69 TPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 107
Score = 39.1 bits (87), Expect = 0.017
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C +PC NGG C P + +C+CP G+ +C +E+G
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEVG 66
Score = 37.5 bits (83), Expect = 0.052
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 9/63 (14%)
Frame = +1
Query: 49 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 73 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 121
Query: 202 GTC 210
G C
Sbjct: 122 GIC 124
>BC053656-1|AAH53656.1| 470|Homo sapiens EDIL3 protein protein.
Length = 470
Score = 60.5 bits (140), Expect = 6e-09
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Frame = +1
Query: 10 YDRGDIQASESCQCENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC 177
+ +GDI + CENGG C + S +C CP G+T C + + V PC
Sbjct: 20 FGKGDI--CDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVE---------VGPC 68
Query: 178 SLHPCRNGGTCKPDR----NSWMNHTCDCPLGYAGASCQ 282
+ +PC NGGTC+ ++++ + C CP G+ G CQ
Sbjct: 69 TPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQ 107
Score = 50.0 bits (114), Expect = 9e-06
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +1
Query: 49 CENGGSCSTESTN---------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
C NGG+C C CP G+ G +C+ I N C + PC+NG
Sbjct: 73 CHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNI-----------NECEVEPCKNG 121
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQ 282
G C + N++C+CP + G +CQ
Sbjct: 122 GIC---TDLVANYSCECPGEFMGRNCQ 145
Score = 39.1 bits (87), Expect = 0.017
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C +PC NGG C P + +C+CP G+ +C +E+G
Sbjct: 26 CDPNPCENGGICLPGLADG-SFSCECPDGFTDPNCSSVVEVG 66
>U77914-1|AAC50909.1| 263|Homo sapiens soluble protein Jagged
protein.
Length = 263
Score = 60.1 bits (139), Expect = 9e-09
Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C + ES C+C G+ G C N CS HPC N GTC D
Sbjct: 11 CHNGGTCVVNGESFTCVCKEGWEGPICAQN-----------TNDCSPHPCYNSGTC-VDG 58
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
++W + C+C G+AG C++ + QS
Sbjct: 59 DNW--YRCECAPGFAGPDCRININECQS 84
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N G+C C C PG+ G C I N C PC G TC +
Sbjct: 49 CYNSGTCVDGDNWYRCECAPGFAGPDCRINI-----------NECQSSPCAFGATCVDEI 97
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
N + C CP G++GA CQ
Sbjct: 98 NGYR---CVCPPGHSGAKCQ 114
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 4/91 (4%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
R +I +S C G +C E C+CPPG++G+ C+ S P
Sbjct: 76 RININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ---------------EVSGRP 120
Query: 190 CRNGGTCKPDRNSWMN--HTCDCPLGYAGAS 276
C G+ PD W + +TC C G S
Sbjct: 121 CITMGSVIPDGAKWDDDCNTCQCLNGRIACS 151
Score = 33.5 bits (73), Expect = 0.85
Identities = 15/35 (42%), Positives = 19/35 (54%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC + S+ TC C G+ G C
Sbjct: 6 CLPNPCHNGGTCVVNGESF---TCVCKEGWEGPIC 37
>U15981-1|AAA75365.1| 310|Homo sapiens dlk protein.
Length = 310
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 14/164 (8%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM--------PLEL-GQSVGFN 318
PC ++ PC++GGTC D + +C CP G++G C++ P E G
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIG 189
Query: 319 GNGYVELPASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQA 450
G+ PA + D+ S P + N G +GQA
Sbjct: 190 GDFRCRCPAGFI--DKTCSRPVTNCASSPCQNGGTCLQHTQGQA 231
>AL356104-4|CAH72941.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/92 (32%), Positives = 39/92 (42%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ S +C C+NGG+C E+ NC+C PG+ G C+ P C C N
Sbjct: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS-----CQPGRYGKRCVPCKCANHS 628
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C P N TC C G+ G C P G
Sbjct: 629 FCHPS-----NGTCYCLAGWTGPDCSQPCPPG 655
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/87 (31%), Positives = 44/87 (50%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
+++CQC +GG+C + +CICP G+TG +C PC C G C
Sbjct: 662 AQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS-QPCQ---CGPGEKCH 717
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
P+ + C CP G++GA C++ ++
Sbjct: 718 PETGA-----CVCPPGHSGAPCRIGIQ 739
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 12/98 (12%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP----VNPCSLHPCRNGGTC 210
C+C N C + C C G+TG C P PP N C +GGTC
Sbjct: 622 CKCANHSFCHPSNGTCYCLAGWTGPDCS--------QPCPPGHWGENCAQTCQCHHGGTC 673
Query: 211 KPDRNS------WMNHTC--DCPLGYAGASCQMPLELG 300
P S W H C CPLG GA+C P + G
Sbjct: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 711
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/87 (31%), Positives = 37/87 (42%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C++ C C C G+ G+ C L VN + C+NGGTC P+
Sbjct: 537 CDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG----VNCSNTCTCKNGGTCLPE- 591
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQ 303
N C C G+ G SCQ + G+
Sbjct: 592 ----NGNCVCAPGFRGPSCQRSCQPGR 614
Score = 50.4 bits (115), Expect = 7e-06
Identities = 32/96 (33%), Positives = 42/96 (43%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
E C C +GG C S C C PGYTG +C AS VN + C N C P
Sbjct: 406 EHCLCLHGGVCQATSGLCQCAPGYTGPHC----ASLCPPDTYGVNCSARCSCENAIACSP 461
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ C C G+ +C +P G + GF+ N
Sbjct: 462 -----IDGECVCKEGWQRGNCSVPCPPG-TWGFSCN 491
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG T +C CPPG+ G+ C P N C NGG C DR
Sbjct: 235 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGLC--DR-- 286
Query: 229 WMNHTCDCPLGYAGASCQMPLELGQ 303
C C GY G C+ +G+
Sbjct: 287 -FTGQCRCAPGYTGDRCREECPVGR 310
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 5/90 (5%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPC-RNGG 204
S+ C+C NGG C + C C PGYTG C E + + + C G
Sbjct: 273 SQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANG 332
Query: 205 TCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
C + + D CP G+ G SCQ P
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 362
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 4/101 (3%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN---PCSL 183
D + S C CEN +CS C+C G+ C P PP C+
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV--------PCPPGTWGFSCNA 492
Query: 184 H-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
C + C P + C C G+ GA CQ+P GQ
Sbjct: 493 SCQCAHEAVCSPQTGA-----CTCTPGWHGAHCQLPCPKGQ 528
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/82 (26%), Positives = 34/82 (41%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
SCQC + CS ++ C C PG+ G++C+ S C + C P
Sbjct: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE----GCASRCDCDHSDGCDP- 547
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
++ C C G+ GA C +
Sbjct: 548 ----VHGRCQCQAGWMGARCHL 565
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/82 (28%), Positives = 33/82 (40%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
+E+C C C + C+C G+TG C R+ PC+ + +C
Sbjct: 316 AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDR-EHSLSCH 374
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P MN C C G+AG C
Sbjct: 375 P-----MNGECSCLPGWAGLHC 391
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/96 (29%), Positives = 32/96 (33%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
Q + C C N SC +S C CP G C P C H G
Sbjct: 143 QCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR-CQCH----GAP 197
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF 315
C P + C CP G SC + G S GF
Sbjct: 198 CDPQTGA-----CFCPAERTGPSCDVSCSQGTS-GF 227
Score = 39.1 bits (87), Expect = 0.017
Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 204
QA +C E+ SC + C C PG+ G +C P C H C +GG
Sbjct: 360 QAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGP-----GCQEHCLCLHGG 414
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASC 279
C+ + C C GY G C
Sbjct: 415 VCQA-----TSGLCQCAPGYTGPHC 434
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/80 (30%), Positives = 31/80 (38%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNH 240
G C + C C PG+ G C + A + P PCS C N +C P +
Sbjct: 112 GRCVAPN-QCQCVPGWRGDDCSSECAPGMWGPQCD-KPCS---CGNNSSCDP-----KSG 161
Query: 241 TCDCPLGYAGASCQMPLELG 300
C CP G +C P G
Sbjct: 162 VCSCPSGLQPPNCLQPCTPG 181
>AL158169-5|CAH70011.1| 1037|Homo sapiens novel protein similar to
mouse Jedi soluble isoform 736 protein protein.
Length = 1037
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/92 (32%), Positives = 39/92 (42%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ S +C C+NGG+C E+ NC+C PG+ G C+ P C C N
Sbjct: 574 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS-----CQPGRYGKRCVPCKCANHS 628
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C P N TC C G+ G C P G
Sbjct: 629 FCHPS-----NGTCYCLAGWTGPDCSQPCPPG 655
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/87 (31%), Positives = 44/87 (50%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
+++CQC +GG+C + +CICP G+TG +C PC C G C
Sbjct: 662 AQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS-QPCQ---CGPGEKCH 717
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
P+ + C CP G++GA C++ ++
Sbjct: 718 PETGA-----CVCPPGHSGAPCRIGIQ 739
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 12/98 (12%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP----VNPCSLHPCRNGGTC 210
C+C N C + C C G+TG C P PP N C +GGTC
Sbjct: 622 CKCANHSFCHPSNGTCYCLAGWTGPDCS--------QPCPPGHWGENCAQTCQCHHGGTC 673
Query: 211 KPDRNS------WMNHTC--DCPLGYAGASCQMPLELG 300
P S W H C CPLG GA+C P + G
Sbjct: 674 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 711
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/87 (31%), Positives = 37/87 (42%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C++ C C C G+ G+ C L VN + C+NGGTC P+
Sbjct: 537 CDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWG----VNCSNTCTCKNGGTCLPE- 591
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQ 303
N C C G+ G SCQ + G+
Sbjct: 592 ----NGNCVCAPGFRGPSCQRSCQPGR 614
Score = 50.4 bits (115), Expect = 7e-06
Identities = 32/96 (33%), Positives = 42/96 (43%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
E C C +GG C S C C PGYTG +C AS VN + C N C P
Sbjct: 406 EHCLCLHGGVCQATSGLCQCAPGYTGPHC----ASLCPPDTYGVNCSARCSCENAIACSP 461
Query: 217 DRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
++ C C G+ +C +P G + GF+ N
Sbjct: 462 -----IDGECVCKEGWQRGNCSVPCPPG-TWGFSCN 491
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG T +C CPPG+ G+ C P N C NGG C DR
Sbjct: 235 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGLC--DR-- 286
Query: 229 WMNHTCDCPLGYAGASCQMPLELGQ 303
C C GY G C+ +G+
Sbjct: 287 -FTGQCRCAPGYTGDRCREECPVGR 310
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 5/90 (5%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYC--ETRIASYLMSPPPPVNPCSLHPC-RNGG 204
S+ C+C NGG C + C C PGYTG C E + + + C G
Sbjct: 273 SQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANG 332
Query: 205 TCKPDRNSWMNHTCD--CPLGYAGASCQMP 288
C + + D CP G+ G SCQ P
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAP 362
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 4/101 (3%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN---PCSL 183
D + S C CEN +CS C+C G+ C P PP C+
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV--------PCPPGTWGFSCNA 492
Query: 184 H-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
C + C P + C C G+ GA CQ+P GQ
Sbjct: 493 SCQCAHEAVCSPQTGA-----CTCTPGWHGAHCQLPCPKGQ 528
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/82 (26%), Positives = 34/82 (41%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
SCQC + CS ++ C C PG+ G++C+ S C + C P
Sbjct: 493 SCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE----GCASRCDCDHSDGCDP- 547
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
++ C C G+ GA C +
Sbjct: 548 ----VHGRCQCQAGWMGARCHL 565
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/82 (28%), Positives = 33/82 (40%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
+E+C C C + C+C G+TG C R+ PC+ + +C
Sbjct: 316 AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDR-EHSLSCH 374
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P MN C C G+AG C
Sbjct: 375 P-----MNGECSCLPGWAGLHC 391
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/96 (29%), Positives = 32/96 (33%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
Q + C C N SC +S C CP G C P C H G
Sbjct: 143 QCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR-CQCH----GAP 197
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGF 315
C P + C CP G SC + G S GF
Sbjct: 198 CDPQTGA-----CFCPAERTGPSCDVSCSQGTS-GF 227
Score = 39.1 bits (87), Expect = 0.017
Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 204
QA +C E+ SC + C C PG+ G +C P C H C +GG
Sbjct: 360 QAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGP-----GCQEHCLCLHGG 414
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASC 279
C+ + C C GY G C
Sbjct: 415 VCQA-----TSGLCQCAPGYTGPHC 434
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/80 (30%), Positives = 31/80 (38%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNH 240
G C + C C PG+ G C + A + P PCS C N +C P +
Sbjct: 112 GRCVAPN-QCQCVPGWRGDDCSSECAPGMWGPQCD-KPCS---CGNNSSCDP-----KSG 161
Query: 241 TCDCPLGYAGASCQMPLELG 300
C CP G +C P G
Sbjct: 162 VCSCPSGLQPPNCLQPCTPG 181
>AK074121-1|BAB84947.1| 491|Homo sapiens FLJ00193 protein protein.
Length = 491
Score = 60.1 bits (139), Expect = 9e-09
Identities = 30/92 (32%), Positives = 39/92 (42%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ S +C C+NGG+C E+ NC+C PG+ G C+ P C C N
Sbjct: 28 VNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS-----CQPGRYGKRCVPCKCANHS 82
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C P N TC C G+ G C P G
Sbjct: 83 FCHPS-----NGTCYCLAGWTGPDCSQPCPPG 109
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/87 (31%), Positives = 44/87 (50%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
+++CQC +GG+C + +CICP G+TG +C PC C G C
Sbjct: 116 AQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCS-QPCQ---CGPGEKCH 171
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
P+ + C CP G++GA C++ ++
Sbjct: 172 PETGA-----CVCPPGHSGAPCRIGIQ 193
Score = 54.0 bits (124), Expect = 6e-07
Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 12/98 (12%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPP----VNPCSLHPCRNGGTC 210
C+C N C + C C G+TG C P PP N C +GGTC
Sbjct: 76 CKCANHSFCHPSNGTCYCLAGWTGPDCS--------QPCPPGHWGENCAQTCQCHHGGTC 127
Query: 211 KPDRNS------WMNHTC--DCPLGYAGASCQMPLELG 300
P S W H C CPLG GA+C P + G
Sbjct: 128 HPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCG 165
Score = 37.1 bits (82), Expect = 0.069
Identities = 18/46 (39%), Positives = 24/46 (52%)
Frame = +1
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
VN + C+NGGTC P+ N C C G+ G SCQ + G+
Sbjct: 28 VNCSNTCTCKNGGTCLPE-----NGNCVCAPGFRGPSCQRSCQPGR 68
>AB018286-1|BAA34463.2| 1205|Homo sapiens KIAA0743 protein protein.
Length = 1205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/185 (29%), Positives = 81/185 (43%), Gaps = 5/185 (2%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL-GYAGASCQMPLELGQSVGFNGNGYVEL 339
P C C N G C W TCDC + Y+G C P G + F +G + L
Sbjct: 820 PSTTCQEDSCANQGVCM---QQWEGFTCDCSMTSYSGNQCNDP---GATYIFGKSGGLIL 873
Query: 340 PASLLRYDELASNPAVIALAVHTT-NDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWD 516
+ D ++ +A+ TT DG+L + P GD+ L IE+G + + ++
Sbjct: 874 -YTWPANDRPSTRSDRLAVGFSTTVKDGILV---RIDSAPGLGDFLQLHIEQGKIGVVFN 929
Query: 517 LGGGLSSIVVD-VPINDGERHQVAARLHEDGHAWLSVDG--VDKSAPATGISNVMNADSN 687
+G SI + P+NDG+ H V G+A L VD V++ P + N +
Sbjct: 930 IGTVDISIKEERTPVNDGKYH-VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQ 988
Query: 688 IYIGG 702
I IGG
Sbjct: 989 IAIGG 993
Score = 39.5 bits (88), Expect = 0.013
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 13/112 (11%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSI-VVDVPINDGERHQVAARLHEDGHAW-LSVDGVDK 639
D+F + + G + L D+G G + NDGE + V + DG + +SV+
Sbjct: 277 DFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVD--IQRDGRSGTISVNSRRT 334
Query: 640 SAPATGISNVMNADSNIYIGGIPS-----------WLNIHGYPGFIGCIENV 762
A+G S +++ + ++Y+GG+P W + Y G++GCI ++
Sbjct: 335 PFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNY-GYVGCIRDL 385
Score = 38.3 bits (85), Expect = 0.030
Identities = 17/65 (26%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCP-LGYAGASCQMPLELGQSVGFNGNGYVELPASL 351
C +PC+N CK + W CDC GY G +C+ + + ++G+ Y+++ +
Sbjct: 418 CDSYPCKNNAVCK---DGWNRFICDCTGTGYWGRTCEREASI---LSYDGSMYMKIIMPM 471
Query: 352 LRYDE 366
+ + E
Sbjct: 472 VMHTE 476
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 59.3 bits (137), Expect = 1e-08
Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRNGGTCK 213
SC C+NGG+C S +C CP G+ G CE P V H C NGG C
Sbjct: 1120 SCLCQNGGTCDPVSGHCACPEGWAGLACEKECL------PRDVRAGCRHSGGCLNGGLCD 1173
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMP 288
P C CP G+ G CQ P
Sbjct: 1174 PHTG-----RCLCPAGWTGDKCQSP 1193
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/111 (32%), Positives = 48/111 (43%), Gaps = 2/111 (1%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PC 177
G +R + +C C NGG C + +C C G+TG +CE L PP C
Sbjct: 1366 GCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAAC 1419
Query: 178 SLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
L C N TC+P TC C G+ G +C+ P GF+G G
Sbjct: 1420 HLECSCHNNSTCEP-----ATGTCRCGPGFYGQACEHPC----PPGFHGAG 1461
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/83 (34%), Positives = 39/83 (46%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S++C C NG SC C C PG+ G C + L N C+NGGTC
Sbjct: 1075 SQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGD----NCRHSCLCQNGGTCD 1130
Query: 214 PDRNSWMNHTCDCPLGYAGASCQ 282
P ++ C CP G+AG +C+
Sbjct: 1131 P-----VSGHCACPEGWAGLACE 1148
Score = 50.4 bits (115), Expect = 7e-06
Identities = 27/80 (33%), Positives = 33/80 (41%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C NGGSC + C CP G+ G+ C P N + C G C P
Sbjct: 1294 CGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGP----NCTHVCGCGQGAACDP-- 1347
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ TC CP G AG C+
Sbjct: 1348 ---VTGTCLCPPGRAGVRCE 1364
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 222
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 602 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 653
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G +G +C+
Sbjct: 654 ---VTGACRCPPGVSGTNCE 670
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCK 213
+ C C+ G C + C+CPPG +G+ C P C+LH C G C
Sbjct: 1507 QRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP-----SCTLHCDCGGGADCD 1561
Query: 214 PDRNSWMNHTCDCPLGYAGASCQM--PLELGQS 306
P ++ C C GY G +C+ PL L ++
Sbjct: 1562 P-----VSGQCHCVDGYMGPTCREGGPLRLPEN 1589
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +1
Query: 16 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 852 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 907
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
N G C P C C G+ G SCQ + G
Sbjct: 908 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 938
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/88 (30%), Positives = 36/88 (40%), Gaps = 1/88 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPD 219
C C++G C S C+CP G+ G +CE P C C G C P
Sbjct: 1466 CWCQHGAPCDPISGRCLCPAGFHGHFCERG-----CEPGSFGEGCHQRCDCDGGAPCDP- 1519
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQ 303
+ C CP G +GA+C + GQ
Sbjct: 1520 ----VTGLCLCPPGRSGATCNLDCRRGQ 1543
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG--- 204
++ C C +C + C CPPG+TGS CE PP C+ G
Sbjct: 1204 AQRCSCPPAAACHHVTGACRCPPGFTGSGCEQ------ACPPGSFGEDCAQMCQCPGENP 1257
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
C P TC C GY G SCQ
Sbjct: 1258 ACHP-----ATGTCSCAAGYHGPSCQ 1278
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 210
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 684 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 737
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
D+ + +C C G+ G CQ ELG
Sbjct: 738 SCDKR---DGSCSCKAGFRGERCQAECELG 764
Score = 46.0 bits (104), Expect = 1e-04
Identities = 24/79 (30%), Positives = 35/79 (44%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 992 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA-- 1045
Query: 223 NSWMNHTCDCPLGYAGASC 279
+N +C CP G G C
Sbjct: 1046 ---VNGSCLCPAGRRGPRC 1061
Score = 45.6 bits (103), Expect = 2e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCE 126
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 640 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 670
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 219
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 905 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 958
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
S + C C GY G C+ G
Sbjct: 959 AISGL---CLCEAGYVGPRCEQQCPQG 982
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C C G GSC S C+C GY G CE + P L C++G C
Sbjct: 945 SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE----QLCQCQHGAAC 1000
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
++ C CP G+ G C+
Sbjct: 1001 -----DHVSGACTCPAGWRGTFCE 1019
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Frame = +1
Query: 34 SESCQCENGG-SCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGG 204
++ CQC +C + C C GY G C+ R PP P C L C NGG
Sbjct: 1247 AQMCQCPGENPACHPATGTCSCAAGYHGPSCQQR------CPPGRYGPGCEQLCGCLNGG 1300
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
+C + C CP G+ G C + G+
Sbjct: 1301 SCDAATGA-----CRCPTGFLGTDCNLTCPQGR 1328
Score = 43.6 bits (98), Expect = 8e-04
Identities = 22/85 (25%), Positives = 34/85 (40%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+ +C C G +C + +C+CP G G C ++ N C NG
Sbjct: 1029 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGH----NCSQACACFNGA 1084
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASC 279
+C P ++ C C G+ G SC
Sbjct: 1085 SCDP-----VHGQCHCAPGWMGPSC 1104
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-CRNG 201
+ S SC C G C + C CPPG TG CE + + P C++
Sbjct: 813 VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHA 867
Query: 202 GTCKPDRNS------WMNHTCD--CPLGYAGASCQ 282
C P+ + ++ C CP G+ G SCQ
Sbjct: 868 ARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 902
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/60 (31%), Positives = 20/60 (33%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C G C S C C GY G C L P S H R T P+R
Sbjct: 1552 CDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGLSGHTARLQQTHIPER 1611
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Frame = +1
Query: 49 CENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
C +GG C S C CPPG+ G C+ V+ C H NGG N
Sbjct: 208 CFHGGRCVPGSAQPCHCPPGFQGPRCQY-----------DVDECRTH---NGGCQHRCVN 253
Query: 226 SWMNHTCDCPLGY 264
+ ++ C+C G+
Sbjct: 254 TPGSYLCECKPGF 266
Score = 30.3 bits (65), Expect = 7.9
Identities = 14/40 (35%), Positives = 18/40 (45%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
CS C +GG C P C CP G+ G CQ ++
Sbjct: 203 CSAGLCFHGGRCVPGSAQ----PCHCPPGFQGPRCQYDVD 238
>D86566-1|BAA13116.1| 955|Homo sapiens notch related protein
protein.
Length = 955
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG+C + + NC CP GYTG C + + C PC NGG+C
Sbjct: 697 SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----------CHSGPCLNGGSCN 745
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG-FNGNGYVELPAS 348
P + C CP + G CQ + S FNG V P +
Sbjct: 746 PSPGGYY---CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.6 bits (123), Expect = 7e-07
Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 40 SCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG+C + +C+C G+ G CE ++ C+ PCRN TC
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP----------SCADSPCRNRATC- 821
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLEL 297
++S C CP GY G SCQ ++L
Sbjct: 822 --QDSPQGPRCLCPTGYTGGSCQTLMDL 847
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 52.4 bits (120), Expect = 2e-06
Identities = 27/81 (33%), Positives = 37/81 (45%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
++C C +G C S C+C G+TG CE + C PC +GGTC P
Sbjct: 663 DNCTCHHG-HCQRSS--CVCDVGWTGPECEAELGG-----------CISAPCAHGGTCYP 708
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ + C CP GY G +C
Sbjct: 709 QPS---GYNCTCPTGYTGPTC 726
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 51.2 bits (117), Expect = 4e-06
Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 2/89 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A S C NGGSC S C CPP +TG C+T + C PC
Sbjct: 729 EMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT-----------STDYCVSAPCF 777
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
NGGTC N +C C +G+ G C+
Sbjct: 778 NGGTCV---NRPGTFSCLCAMGFQGPRCE 803
Score = 50.4 bits (115), Expect = 7e-06
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G +C ++ C CP G+ G C++PL
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGQLCEVPL 628
Score = 50.4 bits (115), Expect = 7e-06
Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Frame = +1
Query: 40 SCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C NGG C S S C CPPG+ GS C+ VNPC PC+NG TC
Sbjct: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCM 946
Query: 214 PDRNSWM 234
+ ++
Sbjct: 947 AQPSGYL 953
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R Q + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C N +C S + C+CP GYTG C+T LM + C+ PC C
Sbjct: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQT-----LM------DLCAQRPCPRNSHCLQTG 863
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFN 318
S+ H C C G+ G C +PL Q +
Sbjct: 864 PSF--H-CLCLQGWTGPLCNLPLSSCQKAALS 892
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSP-PPPVNPCSLHPCRN 198
D+ A C + + S +C+C G+TG C ++S + ++ SL C N
Sbjct: 846 DLCAQRPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL--CHN 903
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GG C +S ++ C CP G+ G+ CQ
Sbjct: 904 GGLCV---DSGPSYFCHCPPGFQGSLCQ 928
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 14/95 (14%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPV------NPCSLHPCRNGG 204
C G SC + C+CP G+TG CE + + + P + L P + G
Sbjct: 598 CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 205 TCKPDRNSWMNH------TCDCPLGYAGASCQMPL 291
P+ N +H +C C +G+ G C+ L
Sbjct: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Score = 35.1 bits (77), Expect = 0.28
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
>DQ138965-1|AAZ66768.1| 203|Homo sapiens truncated brevideltinin
protein.
Length = 203
Score = 58.0 bits (134), Expect = 3e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 43.6 bits (98), Expect = 8e-04
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVC 185
>DQ126100-1|AAZ38943.1| 212|Homo sapiens brevideltin protein.
Length = 212
Score = 58.0 bits (134), Expect = 3e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 50.0 bits (114), Expect = 9e-06
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 5/82 (6%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
+ C CP G+ +C
Sbjct: 187 DIGGDF---RCRCPAGFIDKTC 205
>DQ017081-1|AAY40461.1| 315|Homo sapiens secredeltin protein.
Length = 315
Score = 58.0 bits (134), Expect = 3e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 53.6 bits (123), Expect = 7e-07
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ C CP G+ +C P++
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPVQ 210
>BC014015-1|AAH14015.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 58.0 bits (134), Expect = 3e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 1e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELG-QSVGFNGNGY 330
++ +++ C C + G +C L Q V NGY
Sbjct: 226 HTQVSYECLCKPEFTGLTCVKKRALSPQQVTRLPNGY 262
Score = 31.9 bits (69), Expect = 2.6
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +1
Query: 40 SCQCENGGSC---STESTNCICPPGYTGSYC 123
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>BC013197-1|AAH13197.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 58.0 bits (134), Expect = 3e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 1e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 2.6
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +1
Query: 40 SCQCENGGSC---STESTNCICPPGYTGSYC 123
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>BC007741-1|AAH07741.1| 383|Homo sapiens delta-like 1 homolog
(Drosophila) protein.
Length = 383
Score = 58.0 bits (134), Expect = 3e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 1e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELG-QSVGFNGNGY 330
++ +++ C C + G +C L Q V NGY
Sbjct: 226 HTQVSYECLCKPEFTGLTCVKKRALSPQQVTRLPNGY 262
Score = 31.9 bits (69), Expect = 2.6
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +1
Query: 40 SCQCENGGSC---STESTNCICPPGYTGSYC 123
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>AJ316284-1|CAC87720.2| 1392|Homo sapiens neurexin 3-alpha protein.
Length = 1392
Score = 58.0 bits (134), Expect = 3e-08
Identities = 62/213 (29%), Positives = 85/213 (39%), Gaps = 16/213 (7%)
Frame = +1
Query: 172 PCSLHPCRNGGTCKPDRNSWMNHTCDC-PLGYAGASCQ------MPLELGQSVGFNGNGY 330
PC PC NGG C + TCDC GY G C M E G+S N
Sbjct: 201 PCGERPCENGGICFLLDG---HPTCDCSTTGYGGKLCSEGLSHLMMSEQGRSKAREENVA 257
Query: 331 VELPASLLRYDELASNPAVIALAVHTTNDGVLAYQREGQA--PPNEGDYFLLRIERGFVV 504
+ L YD L+ NP I + +QR G DY L ++ G V
Sbjct: 258 TFRGSEYLCYD-LSQNP--IQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVS 314
Query: 505 LEWDLGGGLSSIVVDV---PINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGIS-NVM 672
L +LG G +V+ ND H V +SVDG+ + T ++
Sbjct: 315 LVINLGSGAFEAIVEPVNGKFNDNAWHDVKV-TRNLRQVTISVDGILTTTGYTQEDYTML 373
Query: 673 NADSNIYIGGIPSWLNIHGYP---GFIGCIENV 762
+D Y+GG PS ++ G P F+GC++ V
Sbjct: 374 GSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEV 406
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/158 (29%), Positives = 70/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPL-GYAGASCQMPLELGQSVGFNGNGYVEL 339
P C C N G C W TCDC + Y+G C P G + F +G + L
Sbjct: 1038 PSTTCQEDSCANQGVCM---QQWEGFTCDCSMTSYSGNQCNDP---GATYIFGKSGGLIL 1091
Query: 340 PASLLRYDELASNPAVIALAVHTT-NDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWD 516
+ D ++ +A+ TT DG+L + P GD+ L IE+G + + ++
Sbjct: 1092 -YTWPANDRPSTRSDRLAVGFSTTVKDGILV---RIDSAPGLGDFLQLHIEQGKIGVVFN 1147
Query: 517 LGGGLSSIVVD-VPINDGERHQVAARLHEDGHAWLSVD 627
+G SI + P+NDG+ H V G+A L VD
Sbjct: 1148 IGTVDISIKEERTPVNDGKYH-VVRFTRNGGNATLQVD 1184
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 1/137 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCP-LGYAGASCQMPLELGQSVGFNGNGYVELPASL 351
C +PC+N CK + W CDC GY G +C+ + + ++G+ Y+++ +
Sbjct: 645 CDSYPCKNNAVCK---DGWNRFICDCTGTGYWGRTCEREASI---LSYDGSMYMKIIMPM 698
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
+ + E A + + ++ V R+ D L ++ G V L +LG G
Sbjct: 699 VMHTE-AEDVSFRFMSQRAYGLLVATTSRD------SADTLRLELDGGRVKLMVNLGKGP 751
Query: 532 SSIVVDVPINDGERHQV 582
++ +ND E H V
Sbjct: 752 ETLYAGQKLNDNEWHTV 768
Score = 39.5 bits (88), Expect = 0.013
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 13/112 (11%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSI-VVDVPINDGERHQVAARLHEDGHAW-LSVDGVDK 639
D+F + + G + L D+G G + NDGE + V + DG + +SV+
Sbjct: 504 DFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVD--IQRDGRSGTISVNSRRT 561
Query: 640 SAPATGISNVMNADSNIYIGGIPS-----------WLNIHGYPGFIGCIENV 762
A+G S +++ + ++Y+GG+P W + Y G++GCI ++
Sbjct: 562 PFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNY-GYVGCIRDL 612
Score = 31.5 bits (68), Expect = 3.4
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 9/162 (5%)
Frame = +1
Query: 295 LGQSVGFNGNGYVELPASLLRYDELASNPAVIALAVHTT-NDGVLAYQREGQAPPNEGDY 471
LG +G G A LR+D AS + ++ T + G+L Y +G D+
Sbjct: 22 LGLCLGLEFMGLPNQWARYLRWD--ASTRSDLSFQFKTNVSTGLLLYLDDGGVC----DF 75
Query: 472 FLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPA 651
L + G V L + + ++++ + +ND H + + L +DG +S
Sbjct: 76 LCLSLVDGRVQLRFSMDCAETAVLSNKQVNDSSWHFLMVS-RDRLRTVLMLDGEGQSGEL 134
Query: 652 TGISNVMNADSNIYIGGI-----PSWLNIHG---YPGFIGCI 753
M+ S++++GG+ PS L + G PGF G I
Sbjct: 135 QPQRPYMDVVSDLFLGGVPTDIRPSALTLDGVQAMPGFKGLI 176
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 58.0 bits (134), Expect = 3e-08
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Frame = +1
Query: 40 SCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C+N G+C+ E C CP Y G C P+N C +PC++GGTC
Sbjct: 349 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTV-----------PINTCIQNPCQHGGTC 397
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQM 285
+ +C CPLG+ G C++
Sbjct: 398 HLSDSHKDGFSCSCPLGFEGQRCEI 422
Score = 48.4 bits (110), Expect = 3e-05
Identities = 43/145 (29%), Positives = 58/145 (40%), Gaps = 17/145 (11%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMS-----------PPPPVNPC 177
E CEN +C N CICPP YTG C+ I + P C
Sbjct: 428 EDNDCENNATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSC 487
Query: 178 SLHPCRNGGTCKPDRNSWMNHTC----DCPLGYAGASCQMPLELGQSVGFNGNGYVELPA 345
P +G C+ D + + H C C G +C P GF+G + E P
Sbjct: 488 ECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP------QGFSG-PFCEHPP 540
Query: 346 SLLRYDELASNPAVIALAVHTTNDG 420
++ YD L+S P + +V T NDG
Sbjct: 541 PMV-YDSLSSPPTTV-YSVETVNDG 563
Score = 39.9 bits (89), Expect = 0.010
Identities = 16/41 (39%), Positives = 20/41 (48%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
N C PC+N GTC D + C CP Y G C +P+
Sbjct: 345 NACLSSPCKNNGTCTQDPVEL--YRCACPYSYKGKDCTVPI 383
Score = 37.1 bits (82), Expect = 0.069
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Frame = +1
Query: 37 ESCQ-CENG--GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+SC C++G S +S C C PG+TG C+ +PC H C + G
Sbjct: 660 KSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR----------DPCLGHRCHH-GK 708
Query: 208 CKPDRNSWMNHTCDCPLGYAGASC 279
C S+M C C GY G C
Sbjct: 709 CVATGTSYM---CKCAEGYGGDLC 729
Score = 33.9 bits (74), Expect = 0.64
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 5/101 (4%)
Frame = +1
Query: 22 DIQASESC---QCENGGSCST-ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
D +A + C +C +G +T S C C GY G C+ + S N CS
Sbjct: 692 DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDS--------ANACSAFK 743
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE-LGQSV 309
C +G D+ C C G++G CQ LGQ V
Sbjct: 744 CHHGQCHISDQG---EPYCLCQPGFSGEHCQQENPCLGQVV 781
>Z12172-1|CAA78163.1| 383|Homo sapiens putative homeotic protein
protein.
Length = 383
Score = 57.6 bits (133), Expect = 5e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 1e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 2.6
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +1
Query: 40 SCQCENGGSC---STESTNCICPPGYTGSYC 123
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>U15979-1|AAA75364.1| 382|Homo sapiens dlk protein.
Length = 382
Score = 57.6 bits (133), Expect = 5e-08
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVN 171
G DR D++A S C N G+C + C C PGY+G C+ +
Sbjct: 82 GELCDR-DVRACSSAPCANNGTCVSLDGGLYECSCAPGYSGKDCQKKDG----------- 129
Query: 172 PCSLH--PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC ++ PC++GGTC D + +C CP G++G C++
Sbjct: 130 PCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 169
Score = 52.8 bits (121), Expect = 1e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 186
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ +C P+
Sbjct: 187 DIGGDF---RCRCPAGFIDKTCSRPV 209
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 179 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 225
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ +++ C C + G +C
Sbjct: 226 HTQVSYECLCKPEFTGLTC 244
Score = 31.9 bits (69), Expect = 2.6
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +1
Query: 40 SCQCENGGSC---STESTNCICPPGYTGSYC 123
S C+NGG+C + S C+C P +TG C
Sbjct: 214 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 244
>DQ309460-1|ABC26875.1| 231|Homo sapiens delta-like 1 protein.
Length = 231
Score = 56.8 bits (131), Expect = 8e-08
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-- 186
D++A S C N G+C + C C PGY+G C+ + PC ++
Sbjct: 1 DVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDG-----------PCVINGS 49
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC++GGTC D + +C CP G++G C++
Sbjct: 50 PCQHGGTCVDDEGRASHASCLCPPGFSGNFCEI 82
Score = 52.8 bits (121), Expect = 1e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Frame = +1
Query: 49 CENGGSCSTES-----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C++GG+C + +C+CPPG++G++CE N C+ +PC N G C
Sbjct: 51 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEI-----------VANSCTPNPCENDGVCT 99
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ +C P+
Sbjct: 100 DIGGDF---RCRCPAGFIDKTCSRPV 122
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CEN G C+ + C CP G+ C PV C+ PC+NGGTC +
Sbjct: 92 CENDGVCTDIGGDFRCRCPAGFIDKTCSR-----------PVTNCASSPCQNGGTCL--Q 138
Query: 223 NSWMNHTCDCPLGYAGASC 279
++ +++ C C + G +C
Sbjct: 139 HTQVSYECLCKPEFTGLTC 157
Score = 31.9 bits (69), Expect = 2.6
Identities = 13/31 (41%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Frame = +1
Query: 40 SCQCENGGSC---STESTNCICPPGYTGSYC 123
S C+NGG+C + S C+C P +TG C
Sbjct: 127 SSPCQNGGTCLQHTQVSYECLCKPEFTGLTC 157
>BC033188-1|AAH33188.1| 152|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 152
Score = 56.8 bits (131), Expect = 8e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +1
Query: 406 TTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQVA 585
T DG+L ++ + PN D+ L + G +V ++LG G++SI+V+ NDG H+V
Sbjct: 6 TAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVK 64
Query: 586 ARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGG---IPSWLNIHGYPGFIGCI 753
A + + ++VD ++ + G+ +N + +Y+GG I N G +GCI
Sbjct: 65 A-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCI 123
Query: 754 EN 759
+
Sbjct: 124 SH 125
>BC033177-1|AAH33177.1| 152|Homo sapiens EGF-like, fibronectin type
III and laminin G domains protein.
Length = 152
Score = 56.8 bits (131), Expect = 8e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +1
Query: 406 TTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQVA 585
T DG+L ++ + PN D+ L + G +V ++LG G++SI+V+ NDG H+V
Sbjct: 6 TAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVK 64
Query: 586 ARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGG---IPSWLNIHGYPGFIGCI 753
A + + ++VD ++ + G+ +N + +Y+GG I N G +GCI
Sbjct: 65 A-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCI 123
Query: 754 EN 759
+
Sbjct: 124 SH 125
>AL359813-6|CAI23221.1| 288|Homo sapiens EGF-like-domain, multiple
9 protein.
Length = 288
Score = 56.8 bits (131), Expect = 8e-08
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSL--HPCRNGGTCKPDR 222
C++G +C + CIC G+ G +C+ PC PCRNGG C+ D+
Sbjct: 2 CQHG-TCH-QPWQCICHSGWAGKFCDKGFHG--RDCERKAGPCEQAGSPCRNGGQCQDDQ 57
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+N TC C +G+ GA C++ ++
Sbjct: 58 GFALNFTCRCLVGFVGARCEVNVD 81
Score = 48.8 bits (111), Expect = 2e-05
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C+ DR
Sbjct: 88 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARCR-DR 135
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP GY G +C++ L
Sbjct: 136 VH--DFDCLCPSGYGGKTCELVL 156
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTE-----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + + C C G+ G+ CE V+ C + PC NG TC
Sbjct: 47 CRNGGQCQDDQGFALNFTCRCLVGFVGARCEVN-----------VDDCLMRPCANGATCL 95
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N + +C CP G+AG C + L+
Sbjct: 96 DGINRF---SCLCPEGFAGRFCTINLD 119
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 126 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 162
>AK092994-1|BAC04013.1| 152|Homo sapiens protein ( Homo sapiens
cDNA FLJ35675 fis, clone SPLEN2018302, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 152
Score = 56.8 bits (131), Expect = 8e-08
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Frame = +1
Query: 406 TTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGERHQVA 585
T DG+L ++ + PN D+ L + G +V ++LG G++SI+V+ NDG H+V
Sbjct: 6 TAKDGLLLWRGDSPMRPNS-DFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVK 64
Query: 586 ARLHEDGHAWLSVDGVD-KSAPATGISNVMNADSNIYIGG---IPSWLNIHGYPGFIGCI 753
A + + ++VD ++ + G+ +N + +Y+GG I N G +GCI
Sbjct: 65 A-VRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCI 123
Query: 754 EN 759
+
Sbjct: 124 SH 125
>BC063815-1|AAH63815.1| 647|Homo sapiens NOTCH4 protein protein.
Length = 647
Score = 56.4 bits (130), Expect = 1e-07
Identities = 33/81 (40%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC---L 491
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ C CP G G C++
Sbjct: 492 DLLATFHCLCPPGLEGQLCEV 512
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-------H-CRNGGTC- 332
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 333 --QNSAGSFHCVCVSGWGGTSCEENLD 357
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 452
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 453 -LNTPGSFNCLCPPGYTGSRCE 473
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 253
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 254 EKDSTF-HLCLCPPGFIGPDCEV 275
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----------PDN-CVSHQCQNGGTC 291
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 292 QDGLDT---YTCLCPETWTGWDCSEDVDECETQG 322
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 157
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 158 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 192
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 212
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 213 NTLGSFQCLCPVGQEGPRCEL 233
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C N C CIC PG++G+ CE ++ C PC NGG C+
Sbjct: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQCQ 567
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
++ H C C G+ G CQ ++
Sbjct: 568 DQPGAF--H-CKCLPGFEGPRCQTEVD 591
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C NGG C + + +C C PG+ G C+T V+ C PC
Sbjct: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE-----------VDECLSDPCP 599
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
G +C ++ C CP G+ G+ + EL +
Sbjct: 600 VGASCLDLPGAFF---CLCPSGFTGSQGRHWKELAE 632
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +C+C G+ G+ CE + + C C G TC DR
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAATCAPGSTC-IDR 373
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +C CP G G C +
Sbjct: 374 VG--SFSCLCPPGRTGLLCHL 392
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C G +C + +C+CPPG G CE N C+ PC N C
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVE-----------TNECASAPCLNHADCHDLL 532
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N + C C G++G C+ ++
Sbjct: 533 NGFQ---CICLPGFSGTRCEEDID 553
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 73
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 74 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 395
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 396 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 434
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 123
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 124 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 156
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
protein.
Length = 1095
Score = 56.0 bits (129), Expect = 1e-07
Identities = 28/80 (35%), Positives = 38/80 (47%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ GS C+ VNPC PC+NG TC + ++ C C GY
Sbjct: 8 CHCPPGFQGSLCQDH-----------VNPCESRPCQNGATCMAQPSGYL---CQCAPGYD 53
Query: 268 GASCQMPLELGQSVGFNGNG 327
G +C L+ QS + +G
Sbjct: 54 GQNCSKELDACQSQPCHNHG 73
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCSTESTN----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
GD+ C G+ + S C C PG+TG +CE I +PC
Sbjct: 97 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-----------DPCHSQ 145
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC +GGTC+ S + C CP G+ G +C
Sbjct: 146 PCFHGGTCEATAGSPLGFICHCPKGFEGPTC 176
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ ES C+NG +C + + C C PGY G C + + C PC N
Sbjct: 23 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-----------DACQSQPCHN 71
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
GTC P + H C CP G+ G C+
Sbjct: 72 HGTCTPKPGGF--H-CACPPGFVGLRCE 96
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
+I S C +GG+C + + C CP G+ G C R S C H
Sbjct: 138 EIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-----------CGFH 186
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
C +GG C P C C GY G C P
Sbjct: 187 HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 220
Score = 35.5 bits (78), Expect = 0.21
Identities = 28/99 (28%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Frame = +1
Query: 49 CENGGSCSTEST-----NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +GG C C C GY G C ++PP P PC G+C
Sbjct: 188 CHHGGLCLPSPKPGFPPRCACLSGYGGPDC--------LTPPAPKGCGPPSPCLYNGSCS 239
Query: 214 PDRN-SWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNG 327
C CP G CQ P G G +G+G
Sbjct: 240 ETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDG 277
>AY043325-1|AAL10682.1| 1406|Homo sapiens CRB1 isoform II precursor
protein.
Length = 1406
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 506
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 507 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 557
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 558 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 617
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 618 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 647
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 727
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 728 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 780
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 781 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 838
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 839 QETELNGGFFKGCIQDV 855
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 887 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 933
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 934 PHGAQCQP 941
>AY043324-1|AAL10681.1| 1376|Homo sapiens CRB1 isoform I precursor
protein.
Length = 1376
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 506
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 507 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 557
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 558 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 617
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 618 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 647
Score = 53.6 bits (123), Expect = 7e-07
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C C + +AG C++
Sbjct: 1317 NKFQ---CLCDVAFAGERCEV 1334
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 727
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 728 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 780
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 781 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 838
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 839 QETELNGGFFKGCIQDV 855
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 887 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 933
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 934 PHGAQCQP 941
Score = 31.1 bits (67), Expect = 4.5
Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIAS 141
DI S C NGG C C+C + G CE ++S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSS 1338
>AL513325-2|CAH72584.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 506
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 507 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 557
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 558 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 617
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 618 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 647
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 727
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 728 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 780
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 781 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 838
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 839 QETELNGGFFKGCIQDV 855
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 887 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 933
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 934 PHGAQCQP 941
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 55.2 bits (127), Expect = 2e-07
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGGT 207
++ C C G +C + C CPPG+TGS CE PP P C L C NGG+
Sbjct: 938 AQRCSCPPGAACHHVTGACRCPPGFTGSGCEQG------CPPGRYGPGCEQLCGCLNGGS 991
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
C + C CP G+ G C + G+
Sbjct: 992 CDAATGA-----CRCPTGFLGTDCNLTCPQGR 1018
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PC 177
G +R + +C C NGG C + +C C G+TG +CE L PP C
Sbjct: 1056 GCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAAC 1109
Query: 178 SLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
L C N TC+P TC C G+ G +C+
Sbjct: 1110 HLECSCHNNSTCEP-----ATGTCRCGPGFYGQACE 1140
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1027 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1081
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQ 303
N +C C LG+ G C++ G+
Sbjct: 1082 ----NGSCSCGLGWTGRHCELACPPGR 1104
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 222
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 422 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 473
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G +G +C+
Sbjct: 474 ---VTGACRCPPGVSGTNCE 490
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 2/90 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRN 198
+ +C C G +C + +C+CP G G C + P V H C N
Sbjct: 849 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCL------PRDVRAGCRHSGGCLN 902
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
GG C P C CP G+ G CQ P
Sbjct: 903 GGLCDPHTG-----RCLCPAGWTGDKCQSP 927
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 7/109 (6%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETR---IASYLMSPPPPVNP-CSLH-PCRNGGT 207
C C N +C + C C PG+ G CE R L P C+LH C G
Sbjct: 1113 CSCHNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1172
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQM--PLELGQSVGFNGNGYVELPAS 348
C P ++ C C GY G +C+ PL L ++ LPAS
Sbjct: 1173 CDP-----VSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPAS 1216
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +1
Query: 16 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 672 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 727
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
N G C P C C G+ G SCQ + G
Sbjct: 728 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 758
Score = 46.4 bits (105), Expect = 1e-04
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+ CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 810 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA 865
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+N +C CP G G C
Sbjct: 866 -----VNGSCLCPAGRRGPRC 881
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 210
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 504 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 557
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
D+ + +C C G+ G CQ ELG
Sbjct: 558 SCDKR---DGSCSCKAGFRGERCQAECELG 584
Score = 45.6 bits (103), Expect = 2e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCE 126
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 460 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 490
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 219
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 725 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 778
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
S + C C GY G C+ G
Sbjct: 779 AISGL---CLCEAGYVGPRCEQQCPQG 802
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C C G GSC S C+C GY G CE + P C C++G C
Sbjct: 765 SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR-CQ---CQHGAAC 820
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
++ C CP G+ G C+
Sbjct: 821 -----DHVSGACTCPAGWRGTFCE 839
Score = 43.6 bits (98), Expect = 8e-04
Identities = 23/78 (29%), Positives = 32/78 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C NGG C + C+CP G+TG C++ CS C G C
Sbjct: 900 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG-EACAQRCS---CPPGAAC-----H 950
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP G+ G+ C+
Sbjct: 951 HVTGACRCPPGFTGSGCE 968
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-CRNG 201
+ S SC C G C + C CPPG TG CE + + P C++
Sbjct: 633 VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHA 687
Query: 202 GTCKPDRNS------WMNHTCD--CPLGYAGASCQ 282
C P+ + ++ C CP G+ G SCQ
Sbjct: 688 ARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 722
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains 6
protein.
Length = 1229
Score = 55.2 bits (127), Expect = 2e-07
Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGGT 207
++ C C G +C + C CPPG+TGS CE PP P C L C NGG+
Sbjct: 938 AQRCSCPPGAACHHVTGACRCPPGFTGSGCEQG------CPPGRYGPGCEQLCGCLNGGS 991
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
C + C CP G+ G C + G+
Sbjct: 992 CDAATGA-----CRCPTGFLGTDCNLTCPQGR 1018
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PC 177
G +R + +C C NGG C + +C C G+TG +CE L PP C
Sbjct: 1056 GCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAAC 1109
Query: 178 SLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
L C N TC+P TC C G+ G +C+
Sbjct: 1110 HLECSCHNNSTCEP-----ATGTCRCGPGFYGQACE 1140
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1027 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1081
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQ 303
N +C C LG+ G C++ G+
Sbjct: 1082 ----NGSCSCGLGWTGRHCELACPPGR 1104
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 222
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 422 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 473
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G +G +C+
Sbjct: 474 ---VTGACRCPPGVSGTNCE 490
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 2/90 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRN 198
+ +C C G +C + +C+CP G G C + P V H C N
Sbjct: 849 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCL------PRDVRAGCRHSGGCLN 902
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
GG C P C CP G+ G CQ P
Sbjct: 903 GGLCDPHTG-----RCLCPAGWTGDKCQSP 927
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 7/109 (6%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETR---IASYLMSPPPPVNP-CSLH-PCRNGGT 207
C C N +C + C C PG+ G CE R L P C+LH C G
Sbjct: 1113 CSCHNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1172
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQM--PLELGQSVGFNGNGYVELPAS 348
C P ++ C C GY G +C+ PL L ++ LPAS
Sbjct: 1173 CDP-----VSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPAS 1216
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +1
Query: 16 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 672 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 727
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
N G C P C C G+ G SCQ + G
Sbjct: 728 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 758
Score = 46.4 bits (105), Expect = 1e-04
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+ CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 810 QRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA 865
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+N +C CP G G C
Sbjct: 866 -----VNGSCLCPAGRRGPRC 881
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 210
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 504 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 557
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
D+ + +C C G+ G CQ ELG
Sbjct: 558 SCDKR---DGSCSCKAGFRGERCQAECELG 584
Score = 45.6 bits (103), Expect = 2e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCE 126
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 460 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 490
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 219
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 725 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 778
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
S + C C GY G C+ G
Sbjct: 779 AISGL---CLCEAGYVGPRCEQQCPQG 802
Score = 44.8 bits (101), Expect = 3e-04
Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C C G GSC S C+C GY G CE + P C C++G C
Sbjct: 765 SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQR-CQ---CQHGAAC 820
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
++ C CP G+ G C+
Sbjct: 821 -----DHVSGACTCPAGWRGTFCE 839
Score = 43.6 bits (98), Expect = 8e-04
Identities = 23/78 (29%), Positives = 32/78 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C NGG C + C+CP G+TG C++ CS C G C
Sbjct: 900 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFG-EACAQRCS---CPPGAAC-----H 950
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP G+ G+ C+
Sbjct: 951 HVTGACRCPPGFTGSGCE 968
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-CRNG 201
+ S SC C G C + C CPPG TG CE + + P C++
Sbjct: 633 VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHA 687
Query: 202 GTCKPDRNS------WMNHTCD--CPLGYAGASCQ 282
C P+ + ++ C CP G+ G SCQ
Sbjct: 688 ARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 722
>AL139136-2|CAI15311.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 506
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 507 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 557
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 558 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 617
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 618 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 647
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 727
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 728 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 780
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 781 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 838
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 839 QETELNGGFFKGCIQDV 855
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 887 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 933
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 934 PHGAQCQP 941
>AL136322-3|CAI16646.1| 1406|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1406
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1317 NKFQ---CLCDVAFAGERCEVDL 1336
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 506
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 507 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 557
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 558 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 617
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 618 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 647
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 727
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 728 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 780
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 781 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 838
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 839 QETELNGGFFKGCIQDV 855
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 887 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 933
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 934 PHGAQCQP 941
>AF154671-1|AAF01361.1| 1376|Homo sapiens CRB1 protein.
Length = 1376
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 202 --LNEIGRYTCICPHNYSGVNCELEID 226
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 397 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 450
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 506
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 507 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 557
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 558 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 617
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 618 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 647
Score = 53.6 bits (123), Expect = 7e-07
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1268 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1316
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N + C C + +AG C++
Sbjct: 1317 NKFQ---CLCDVAFAGERCEV 1334
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 383 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 424
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 317
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 318 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 371
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 676 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 727
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 728 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 780
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 781 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 838
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 839 QETELNGGFFKGCIQDV 855
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1188
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1189 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1220
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1214 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1268
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1269 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1299
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 224 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 272
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 273 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1189 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1234
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1235 GYSCLCFGNFTGKFCR 1250
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 889 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 923
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 887 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 933
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 934 PHGAQCQP 941
Score = 31.1 bits (67), Expect = 4.5
Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIAS 141
DI S C NGG C C+C + G CE ++S
Sbjct: 1297 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDVSS 1338
>AB208923-1|BAD92160.1| 441|Homo sapiens crumbs homolog 1 isoform
II precursor variant protein.
Length = 441
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 179 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 226
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N +TC CP Y+G +C++ ++
Sbjct: 227 --LNEIGRYTCICPHNYSGVNCELEID 251
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 104 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 152
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 153 DP---IYPVCICPAGYAGRFCEI 172
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/115 (33%), Positives = 53/115 (46%), Gaps = 3/115 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C +GG C +C C G+TG++CET LM P+ C PC N TC+
Sbjct: 296 CLHGGLCVDGENRYSCNCTGSGFTGTHCET-----LM----PL--CWSKPCHNNATCE-- 342
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
+S N+TC C GY GA C++ L S NG +S +Y + P+
Sbjct: 343 -DSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 396
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 144 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 192
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 193 D---GYSCFCVPGYQGRHCDLEVD 213
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+I S C NG +C + C C PG+ G +CE + C+ PC
Sbjct: 249 EIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN-----------TDECASQPCL 297
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ--MPL 291
+GG C N ++C+C G+ G C+ MPL
Sbjct: 298 HGGLCVDGEN---RYSCNCTGSGFTGTHCETLMPL 329
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 97 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 133
>AL513325-3|CAM17208.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 54.8 bits (126), Expect = 3e-07
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCP---LGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
N +TC CP GY GA C++ L S NG +S +Y + P+
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 259
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 394
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 395 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 445
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 446 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 505
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 506 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 535
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 615
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 616 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 668
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 669 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 726
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 727 QETELNGGFFKGCIQDV 743
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 775 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 821
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 822 PHGAQCQP 829
>AL139136-3|CAM21656.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 54.8 bits (126), Expect = 3e-07
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCP---LGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
N +TC CP GY GA C++ L S NG +S +Y + P+
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 259
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 394
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 395 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 445
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 446 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 505
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 506 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 535
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 615
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 616 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 668
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 669 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 726
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 727 QETELNGGFFKGCIQDV 743
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 775 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 821
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 822 PHGAQCQP 829
>AL136322-4|CAM23328.1| 1294|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 1294
Score = 54.8 bits (126), Expect = 3e-07
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCP---LGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
N +TC CP GY GA C++ L S NG +S +Y + P+
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 259
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 394
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 395 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 445
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 446 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 505
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 506 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 535
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 615
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 616 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 668
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 669 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 726
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 727 QETELNGGFFKGCIQDV 743
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 775 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 821
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 822 PHGAQCQP 829
>AJ748821-1|CAG38658.1| 1294|Homo sapiens crumbs homologue 1
(alternative protein) protein.
Length = 1294
Score = 54.8 bits (126), Expect = 3e-07
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 5/120 (4%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C+NG C + +C C PGY G +C+ V+ C+ PC+N TC
Sbjct: 154 SSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLE-----------VDECASDPCKNEATC- 201
Query: 214 PDRNSWMNHTCDCP---LGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPA 384
N +TC CP GY GA C++ L S NG +S +Y + P+
Sbjct: 202 --LNEIGRYTCICPHNYSGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPS 259
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C+ T C+C PG+TG +CE ++ C+ PC NGG C+
Sbjct: 1156 CYNGGNCTEFQTELKCMCRPGFTGEWCE-----------KDIDECASDPCVNGGLCQDLL 1204
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
N + C C + +AG C++ L
Sbjct: 1205 NKFQ---CLCDVAFAGERCEVDL 1224
Score = 53.6 bits (123), Expect = 7e-07
Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 22/270 (8%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICP-PGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
D+ S C+NGG+C N C CP + ++ R S ++ C+ C
Sbjct: 285 DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL------GCTHQQC 338
Query: 193 RNGGTCKPD-RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDEL 369
N GTC P ++ +C CP GY G+ C E+ ++ F G+G++ + + +
Sbjct: 339 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLC----EIATTLSFEGDGFLWVKSGSVTTKGS 394
Query: 370 ASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSIVVD 549
N IAL T L R N + L + G++ L + S +++
Sbjct: 395 VCN---IALRFQTVQPMALLLFRS-----NRDVFVKLELLSGYIHLSIQV-NNQSKVLLF 445
Query: 550 VPIN--DGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADS-----NIYIGGIP 708
+ N DGE H V E L D + A + + + S N ++GG+P
Sbjct: 446 ISHNTSDGEWHFVEVIFAEAVTLTLIDDSCKEKCIAKAPTPLESDQSICAFQNSFLGGLP 505
Query: 709 -----------SWLNIHGYPGFIGCIENVE 765
++ N+ P F+GC+++++
Sbjct: 506 VGMTSNGVALLNFYNMPSTPSFVGCLQDIK 535
Score = 52.8 bits (121), Expect = 1e-06
Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSC----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C+ +C S C CPPGY+G+ CET I S C + C++GG C
Sbjct: 79 CQGSATCVNTPGERSFLCKCPPGYSGTICETTIGS-----------CGKNSCQHGGICHQ 127
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
D + C CP GYAG C++
Sbjct: 128 DP---IYPVCICPAGYAGRFCEI 147
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/56 (46%), Positives = 32/56 (57%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCP 255
CIC PG+TG +CE VN CS +PC+NGGTC+ N N+TC CP
Sbjct: 271 CICQPGFTGIHCEE-----------DVNECSSNPCQNGGTCE---NLPGNYTCHCP 312
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 564 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 615
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 616 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 668
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 669 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 726
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 727 QETELNGGFFKGCIQDV 743
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C + CICP GY G +CE + C+ PC+NG C+
Sbjct: 119 CQHGGICHQDPIYPVCICPAGYAGRFCEI-----------DHDECASSPCQNGAVCQDGI 167
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
+ ++C C GY G C + ++
Sbjct: 168 D---GYSCFCVPGYQGRHCDLEVD 188
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 1028 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 1076
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 1077 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 1108
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 1102 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 1156
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
NGG C + C C G+ G C+ ++
Sbjct: 1157 YNGGNCTEFQTEL---KCMCRPGFTGEWCEKDID 1187
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 1077 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 1122
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 1123 GYSCLCFGNFTGKFCR 1138
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 777 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 811
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Frame = +1
Query: 169 NPCSLHPCRNGGTC--KPDRNSWMNHTCDCPLGYAGASCQ 282
+PC +PC+ TC P S++ C CP GY+G C+
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFL---CKCPPGYSGTICE 108
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 2/46 (4%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMS 153
DI S C NGG C C+C + G CE +A L+S
Sbjct: 1185 DIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1230
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 775 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 821
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 822 PHGAQCQP 829
>AB023961-1|BAB20317.1| 502|Homo sapiens notch4 protein.
Length = 502
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S QC+NGG+C ++ C+CP +TG C + PP H CRNGGTC
Sbjct: 281 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECEAQGPP-------H-CRNGGTC- 331
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
+NS + C C G+ G SC+ L+
Sbjct: 332 --QNSAGSFHCVCVSGWGGTSCEENLD 356
Score = 53.6 bits (123), Expect = 7e-07
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Frame = +1
Query: 49 CENGGSCSTE----STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
C CST ST C+C PGY+G C + LM+ P PC +GG+C
Sbjct: 400 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP------SPCEHGGSC-- 451
Query: 217 DRNSWMNHTCDCPLGYAGASCQ 282
N+ + C CP GY G+ C+
Sbjct: 452 -LNTPGSFNCLCPPGYTGSRCE 472
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/83 (36%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Frame = +1
Query: 49 CENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK--P 216
C G SC S C+CP G G CE R PC C NGGTC+ P
Sbjct: 204 CPKGTSCHNTLGSFQCLCPVGQEGPRCELR-----------AGPCPPRGCSNGGTCQLMP 252
Query: 217 DRNSWMNHTCDCPLGYAGASCQM 285
+++S H C CP G+ G C++
Sbjct: 253 EKDSTF-HLCLCPPGFIGPGCEV 274
Score = 51.6 bits (118), Expect = 3e-06
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 49 CENGGSCST----ESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C NGG+C +ST C+CPPG+ G CE P N C H C+NGGTC
Sbjct: 242 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPGCEVN----------PDN-CVSHQCQNGGTC 290
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVG 312
+ ++ +TC CP + G C ++ ++ G
Sbjct: 291 QDGLDT---YTCLCPETWTGWDCSEDVDECEAQG 321
Score = 51.2 bits (117), Expect = 4e-06
Identities = 27/56 (48%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
CE+GGSC + S NC+CPPGYTGS CE A + N C PC G TC
Sbjct: 445 CEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADH--------NECLSQPCHPGSTC 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 6/100 (6%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQ---CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPP 162
G T +R + + C C G C +++ C C PG+TG C+ R
Sbjct: 107 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR---------- 156
Query: 163 PVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ CS +PC NGG C ++ C CP G+ G +C+
Sbjct: 157 --DFCSANPCVNGGVCLA---TYPQIQCHCPPGFEGHACE 191
Score = 44.8 bits (101), Expect = 3e-04
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C CPPG+ G CE + P PC G +C
Sbjct: 164 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP---------GPCPKGTSC---H 211
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
N+ + C CP+G G C++
Sbjct: 212 NTLGSFQCLCPVGQEGPRCEL 232
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
D + +A C NGG+C S S +C+C G+ G+ CE + + C
Sbjct: 313 DVDECEAQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL-----------DDCIAA 361
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G TC DR + +C CP G G C +
Sbjct: 362 TCAPGSTC-IDRVG--SFSCLCPPGRTGLLCHL 391
Score = 38.7 bits (86), Expect = 0.023
Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 14/107 (13%)
Frame = +1
Query: 16 RGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
RG + S C NGG+C + S C C PG+ G C+ P P L
Sbjct: 23 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF---------PDPCQNAQL- 72
Query: 187 PCRNGGTCK---------PDRNSWM--NHTCDCPLGYAGASCQMPLE 294
C+NGG+C+ P S + + C C G+ G CQ LE
Sbjct: 73 -CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 118
Score = 37.5 bits (83), Expect = 0.052
Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 2/100 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T ++ + C G +C S +C+CPPG TG C +
Sbjct: 347 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE------------DM 394
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C PC C + + C C GY+G +C L+
Sbjct: 395 CLSQPCHGDAQCSTNPLTGST-LCLCQPGYSGPTCHQDLD 433
Score = 35.5 bits (78), Expect = 0.21
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 16/95 (16%)
Frame = +1
Query: 49 CENGGSCS----------------TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
C+NGGSC T S C C PG+TG C+ ++ +PC
Sbjct: 73 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE----------DPCP 122
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C G C + C C G+ G CQ+
Sbjct: 123 PSFCSKRGRCHIQASG--RPQCSCMPGWTGEQCQL 155
>BC000218-1|AAH00218.1| 618|Homo sapiens delta-like 3 (Drosophila)
protein.
Length = 618
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSC-----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + C CPPG+ GS CE R V+ CSL PCRNGG C
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR-----------VDRCSLQPCRNGGLCL 369
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
D + C C G+AG C+ L+
Sbjct: 370 -DLGHALR--CRCRAGFAGPRCEHDLD 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSCS S C CP G+ G CE + C+ PC NGG C
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVT-----------CADGPCFNGGLCVGGA 331
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + C CP G+ G++C+
Sbjct: 332 DPDSAYICHCPPGFQGSNCE 351
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C + C C G+ G C R +PC+ PC +GG C
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRER-----------ADPCAARPCAHGGRCYA-- 446
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C C GY GA C+ P+
Sbjct: 447 -HFSGLVCACAPGYMGARCEFPV 468
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIA-SYLMSPPPPVN-----------PCSLH 186
C E+G C + C C G+TG C ++ S +SP P + PC +
Sbjct: 224 CSPEHG-FCE-QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGN 281
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC NGG+C S+ C CP G+ G C++
Sbjct: 282 PCANGGSCSETPRSF---ECTCPRGFYGLRCEV 311
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C C G+ G CE + + C+ C NGGTC
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-----------DDCAGRACANGGTCVEGG 410
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ H C C LG+ G C+
Sbjct: 411 GA---HRCSCALGFGGRDCR 427
Score = 35.1 bits (77), Expect = 0.28
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRI----ASYLMSPPPPVNP 174
C +GG C + C C PGY G+ CE + AS L + PP + P
Sbjct: 438 CAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLRP 485
>AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens
cDNA FLJ90821 fis, clone Y79AA1001328, highly similar to
Delta-like protein 3 precursor. ).
Length = 587
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSC-----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + C CPPG+ GS CE R V+ CSL PCRNGG C
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR-----------VDRCSLQPCRNGGLCL 369
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
D + C C G+AG C+ L+
Sbjct: 370 -DLGHALR--CRCRAGFAGPRCEHDLD 393
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSCS S C CP G+ G CE + C+ PC NGG C
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVT-----------CANGPCFNGGLCVGGA 331
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + C CP G+ G++C+
Sbjct: 332 DPDSAYICHCPPGFQGSNCE 351
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C + C C G+ G C R +PC++ PC +GG C
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRER-----------ADPCAVRPCAHGGRCYA-- 446
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C C GY GA C+ P+
Sbjct: 447 -HFSGLVCACAPGYMGARCEFPV 468
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIA-SYLMSPPPPVN-----------PCSLH 186
C E+G C + C C G+TG C ++ S +SP P + PC +
Sbjct: 224 CSPEHG-FCE-QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGN 281
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC NGG+C S+ C CP G+ G C++
Sbjct: 282 PCANGGSCSETPRSF---ECTCPRGFYGLRCEV 311
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C C G+ G CE + + C+ C NGGTC
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-----------DDCAGRACANGGTCVEGG 410
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ H C C LG+ G C+
Sbjct: 411 GA---HRCSCALGFGGRDCR 427
>AF241373-1|AAF62542.1| 618|Homo sapiens DLL3 protein precursor
protein.
Length = 618
Score = 54.4 bits (125), Expect = 4e-07
Identities = 34/87 (39%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSC-----STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C NGG C + C CPPG+ GS CE R V+ CSL PCRNGG C
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKR-----------VDRCSLQPCRNGGLCL 369
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
D + C C G+AG C+ L+
Sbjct: 370 -DLGHALR--CRCRAGFAGPRCEHDLD 393
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSCS S C CP G+ G CE + C+ PC NGG C
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVT-----------CADGPCFNGGLCVGGA 331
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ + C CP G+ G++C+
Sbjct: 332 DPDSAYICHCPPGFQGSNCE 351
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C + C C G+ G C R +PC+ PC +GG C
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRER-----------ADPCAARPCAHGGRCYA-- 446
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C C GY GA C+ P+
Sbjct: 447 -HFSGLVCACAPGYMGARCEFPV 468
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 12/93 (12%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIA-SYLMSPPPPVN-----------PCSLH 186
C E+G C + C C G+TG C ++ S +SP P + PC +
Sbjct: 224 CSPEHG-FCE-QPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGN 281
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
PC NGG+C S+ C CP G+ G C++
Sbjct: 282 PCANGGSCSETPRSF---ECTCPRGFYGLRCEV 311
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C + C C G+ G CE + + C+ C NGGTC
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL-----------DDCAGRACANGGTCVEGG 410
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ H C C LG+ G C+
Sbjct: 411 GA---HRCSCALGFGGRDCR 427
Score = 35.1 bits (77), Expect = 0.28
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRI----ASYLMSPPPPVNP 174
C +GG C + C C PGY G+ CE + AS L + PP + P
Sbjct: 438 CAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLRP 485
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVN-PC 177
G +R + +C C NGG C + +C C G+TG +CE L PP C
Sbjct: 1073 GCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE------LACPPGRYGAAC 1126
Query: 178 SLH-PCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
L C N TC+P TC C G+ G +C+
Sbjct: 1127 HLECSCHNNSTCEP-----ATGTCRCGPGFYGQACE 1157
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-C-SLHPCRNGGT 207
++ C C +C + C CPPG+TGS CE PP P C L C NGG+
Sbjct: 955 AQRCSCPPAAACHHVTGACRCPPGFTGSGCEQG------CPPGRYGPGCEQLCGCLNGGS 1008
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPLELGQ 303
C + C CP G+ G C + G+
Sbjct: 1009 CDAATGA-----CRCPTGFLGTDCNLTCPQGR 1035
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/87 (32%), Positives = 37/87 (42%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C G +C + C+CPPG G CE + CS CRNGG C
Sbjct: 1044 CGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCE-HTCS---CRNGGLCHAS- 1098
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQ 303
N +C C LG+ G C++ G+
Sbjct: 1099 ----NGSCSCGLGWTGRHCELACPPGR 1121
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTCKPDR 222
C NGG+C C CP G+TG C PP CS C+NGGTC
Sbjct: 439 CRNGGTCLLGLDGCDCPEGWTGLICNE------TCPPDTFGKNCSFSCSCQNGGTCDS-- 490
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G +G +C+
Sbjct: 491 ---VTGACRCPPGVSGTNCE 507
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 2/90 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP--CRN 198
+ +C C G +C + +C+CP G G C + P V H C N
Sbjct: 866 LDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAEKCL------PRDVRAGCRHSGGCLN 919
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
GG C P C CP G+ G CQ P
Sbjct: 920 GGLCDPHTG-----RCLCPAGWTGDKCQSP 944
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 7/109 (6%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETR---IASYLMSPPPPVNP-CSLH-PCRNGGT 207
C C N +C + C C PG+ G CE R L P C+LH C G
Sbjct: 1130 CSCHNNSTCEPATGTCRCGPGFYGQACEHRRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1189
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQM--PLELGQSVGFNGNGYVELPAS 348
C P ++ C C GY G +C+ PL L ++ LPAS
Sbjct: 1190 CDP-----VSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPAS 1233
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/96 (30%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Frame = +1
Query: 16 RGDIQASESCQ-CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
R + E C C++ C E+ C+C PG+ GS C+ + P CS C
Sbjct: 689 RWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTR-CS---C 744
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
N G C P C C G+ G SCQ + G
Sbjct: 745 ANDGHCHPATGH-----CSCAPGWTGFSCQRACDTG 775
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNP-CSLH-PCRNGGTC 210
+ C C N G C C+C PG G +C +L PP P CS C T
Sbjct: 521 KKCNCANRGRCHRLYGACLCDPGLYGRFC------HLTCPPWAFGPGCSEECQCVQPHTQ 574
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
D+ + +C C G+ G CQ ELG
Sbjct: 575 SCDKR---DGSCSCKAGFRGERCQAECELG 601
Score = 46.0 bits (104), Expect = 1e-04
Identities = 24/79 (30%), Positives = 35/79 (44%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
CQC++G +C S C CP G+ G++CE + ++ S C G C
Sbjct: 829 CQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFG----LDCRSACNCTAGAACDA-- 882
Query: 223 NSWMNHTCDCPLGYAGASC 279
+N +C CP G G C
Sbjct: 883 ---VNGSCLCPAGRRGPRC 898
Score = 45.6 bits (103), Expect = 2e-04
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCE 126
S SC C+NGG+C + + C CPPG +G+ CE
Sbjct: 477 SFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 507
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPD 219
C C N G C + +C C PG+TG C+ + P CS HPC + G D
Sbjct: 742 CSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP-----DCS-HPCNCSAGHGSCD 795
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELG 300
S + C C GY G C+ G
Sbjct: 796 AISGL---CLCEAGYVGPRCEQQCPQG 819
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
Frame = +1
Query: 34 SESCQCENG-GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
S C C G GSC S C+C GY G CE + P L C++G C
Sbjct: 782 SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCE----QLCQCQHGAAC 837
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQ 282
++ C CP G+ G C+
Sbjct: 838 -----DHVSGACTCPAGWRGTFCE 856
Score = 42.3 bits (95), Expect = 0.002
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN- 225
C NGG C + C+CP G+TG C++ P + C +C P
Sbjct: 917 CLNGGLCDPHTGRCLCPAGWTGDKCQS----------PCLRGWFGEACAQRCSCPPAAAC 966
Query: 226 SWMNHTCDCPLGYAGASCQ 282
+ C CP G+ G+ C+
Sbjct: 967 HHVTGACRCPPGFTGSGCE 985
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-CRNG 201
+ S SC C G C + C CPPG TG CE + + P C++
Sbjct: 650 VNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG----LGCQEICPACQHA 704
Query: 202 GTCKPDRNS------WMNHTCD--CPLGYAGASCQ 282
C P+ + ++ C CP G+ G SCQ
Sbjct: 705 ARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQ 739
>AY720432-1|AAU14134.1| 1285|Homo sapiens crumbs-like protein 2
precursor protein.
Length = 1285
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 282
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 268 GASCQ 282
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 181 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
P GG P S+ + C CP G+ GA C + + E NG +
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 337 LP 342
LP
Sbjct: 338 LP 339
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 28 QASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ S + C +G C + + NC C G G C+ P PC +PC NG
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-----------PTLPCEANPCLNG 1185
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQM 285
GTC R + C C ++G C++
Sbjct: 1186 GTC---RAAGGVSECICNARFSGQFCEV 1210
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 265 AGASCQMPLE 294
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 39.9 bits (89), Expect = 0.010
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCARG-RCHTHP 1112
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ G C++P+
Sbjct: 1113 DG--RFECRCPPGFGGPRCRLPV 1133
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 38.3 bits (85), Expect = 0.030
Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 4/92 (4%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PC 192
+ S C G C T C CPPG+ G C P P CSL+ C
Sbjct: 1095 VDPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRL---------PVPSKECSLNVTC 1144
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
+G C+ + C C G AG CQ+P
Sbjct: 1145 LDGSPCEGGSPA---ANCSCLEGLAGQRCQVP 1173
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES--TNCICPPGYTGSYCETRIASYLMSPPP 162
E+ C NGG+C + CIC ++G +CE +A L P P
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE--VAKGLPLPLP 1219
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 210
C NGG+C + +C CP +TG C A L P P + P + +G C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL445489-4|CAI39793.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 282
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 268 GASCQ 282
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 181 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
P GG P S+ + C CP G+ GA C + + E NG +
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 337 LP 342
LP
Sbjct: 338 LP 339
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 28 QASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ S + C +G C + + NC C G G C+ P PC +PC NG
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-----------PTLPCEANPCLNG 1185
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQM 285
GTC R + C C ++G C++
Sbjct: 1186 GTC---RAAGGVSECICNARFSGQFCEV 1210
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 265 AGASCQMPLE 294
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 39.9 bits (89), Expect = 0.010
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCARG-RCHTHP 1112
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ G C++P+
Sbjct: 1113 DG--RFECRCPPGFGGPRCRLPV 1133
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 38.3 bits (85), Expect = 0.030
Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 4/92 (4%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PC 192
+ S C G C T C CPPG+ G C P P CSL+ C
Sbjct: 1095 VDPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRL---------PVPSKECSLNVTC 1144
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
+G C+ + C C G AG CQ+P
Sbjct: 1145 LDGSPCEGGSPA---ANCSCLEGLAGQRCQVP 1173
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES--TNCICPPGYTGSYCETRIASYLMSPPP 162
E+ C NGG+C + CIC ++G +CE +A L P P
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE--VAKGLPLPLP 1219
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 210
C NGG+C + +C CP +TG C A L P P + P + +G C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL445489-3|CAM14433.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 282
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 268 GASCQ 282
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 181 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
P GG P S+ + C CP G+ GA C + + E NG +
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 337 LP 342
LP
Sbjct: 338 LP 339
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 265 AGASCQMPLE 294
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCAR-GRCHTHP 1112
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G+ G C+
Sbjct: 1113 DG--RFECRCPPGFGGPRCR 1130
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 210
C NGG+C + +C CP +TG C A L P P + P + +G C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL365504-3|CAI41011.1| 1285|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1285
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 282
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 268 GASCQ 282
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 181 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
P GG P S+ + C CP G+ GA C + + E NG +
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 337 LP 342
LP
Sbjct: 338 LP 339
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Frame = +1
Query: 28 QASESCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
+ S + C +G C + + NC C G G C+ P PC +PC NG
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQV-----------PTLPCEANPCLNG 1185
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQM 285
GTC R + C C ++G C++
Sbjct: 1186 GTC---RAAGGVSECICNARFSGQFCEV 1210
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 265 AGASCQMPLE 294
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 39.9 bits (89), Expect = 0.010
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCARG-RCHTHP 1112
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ C CP G+ G C++P+
Sbjct: 1113 DG--RFECRCPPGFGGPRCRLPV 1133
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 38.3 bits (85), Expect = 0.030
Identities = 28/92 (30%), Positives = 35/92 (38%), Gaps = 4/92 (4%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PC 192
+ S C G C T C CPPG+ G C P P CSL+ C
Sbjct: 1095 VDPCHSAPCARG-RCHTHPDGRFECRCPPGFGGPRCRL---------PVPSKECSLNVTC 1144
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAGASCQMP 288
+G C+ + C C G AG CQ+P
Sbjct: 1145 LDGSPCEGGSPA---ANCSCLEGLAGQRCQVP 1173
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES--TNCICPPGYTGSYCETRIASYLMSPPP 162
E+ C NGG+C + CIC ++G +CE +A L P P
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCE--VAKGLPLPLP 1219
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 210
C NGG+C + +C CP +TG C A L P P + P + +G C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AL365504-2|CAM21391.1| 1176|Homo sapiens crumbs homolog 2
(Drosophila) protein.
Length = 1176
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
RN + C CPLGYAG +C+M ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCEMEVD 148
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +G +C + C CP GY G CE V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME-----------VDECASAPCL 156
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
+GG+C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGGSCLDGVGSFR---CVCAPGYGGTRCQLDLDECQS 190
Score = 50.8 bits (116), Expect = 5e-06
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C +GGSC S C+C PGY G+ C+ ++ C PC
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQL-----------DLDECQSQPCA 194
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 282
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 268 GASCQ 282
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 181 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
P GG P S+ + C CP G+ GA C + + E NG +
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 337 LP 342
LP
Sbjct: 338 LP 339
Score = 40.3 bits (90), Expect = 0.007
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPTGFRCYCVPGF 100
Query: 265 AGASCQMPLE 294
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCAR-GRCHTHP 1112
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G+ G C+
Sbjct: 1113 DG--RFECRCPPGFGGPRCR 1130
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 210
C NGG+C + +C CP +TG C A L P P + P + +G C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AB076400-1|BAB86868.1| 1097|Homo sapiens fat3 protein.
Length = 1097
Score = 53.6 bits (123), Expect = 7e-07
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 4/112 (3%)
Frame = +1
Query: 31 ASESCQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
A + C++GGSC+ + C C +TG CE+ I + C +PCRNG
Sbjct: 532 ACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITA-----------CFPNPCRNG 580
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPL-ELGQSVGFNGNGYVELPASLL 354
G+C P N+++ C+C G G +C+ + E + NG V + S L
Sbjct: 581 GSCDPIGNTFI---CNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFL 629
Score = 46.0 bits (104), Expect = 1e-04
Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSC C C G TG CE I N C C NGG+C
Sbjct: 577 CRNGGSCDPIGNTFICNCKAGLTGVTCEEDI-----------NECEREECENGGSCV--- 622
Query: 223 NSWMNHTCDCPLGYAGASC 279
N + + C+C GY G C
Sbjct: 623 NVFGSFLCNCTPGYVGQYC 641
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETR 132
DI E +CENGGSC S C C PGY G YC R
Sbjct: 606 DINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLR 644
Score = 41.5 bits (93), Expect = 0.003
Identities = 58/242 (23%), Positives = 90/242 (37%), Gaps = 11/242 (4%)
Frame = +1
Query: 70 STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCD 249
ST + +CP Y C P +PC PC C S C
Sbjct: 276 STARISFVCPRFYRNVRCTCNGGLC----PGSNDPCVEKPCPGDMQCVGYEASRRPFLCQ 331
Query: 250 CPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALAVHT-TNDGVL 426
CP G G C S+ F GN Y++ S + +AL + T ++G++
Sbjct: 332 CPPGKLG-ECSG----HTSLSFAGNSYIKYRLS----ENSKEEDFKLALRLRTLQSNGII 382
Query: 427 AYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSSI-VVDVPINDGERHQVAARLHED 603
Y R A P +L+I G + + D G G + + +NDG H V L+ +
Sbjct: 383 MYTR---ANP----CIILKIVDGKLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRN 435
Query: 604 GHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSWLNIHG---------YPGFIGCIE 756
+ D + A ++ +S+IY G + NI GF GC++
Sbjct: 436 FTSLSLDDSYVERRRAPLYFQTLSTESSIYFGALVQADNIRSLTDTRVTQVLSGFQGCLD 495
Query: 757 NV 762
+V
Sbjct: 496 SV 497
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/115 (35%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Frame = +1
Query: 1 GNTYD-RGDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPP 165
GN Y G +Q S C C NG T S C C G+TG C I
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI---------- 433
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQSV-GFNGN 324
N C +PC NGGTC +S+ +C+C + GA CQ+P ++ G+S+ G NG+
Sbjct: 434 -NECLSNPCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGESLSGINGS 484
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D + S C+NGG+C +S CICPP + G C + + P++ C+
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS------CQ 185
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC N+ +++C CP G C
Sbjct: 186 NGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 35.1 bits (77), Expect = 0.28
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Frame = +1
Query: 34 SESCQCENGG-----SCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
++ C NGG SCS+ + C C PGYTG+ L N C HP
Sbjct: 350 TDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS------NICLSHP 403
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C N G C ++ + C C G+ G +C
Sbjct: 404 CLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 132
+I + C+NGG+C + S +C CPP G C ++
Sbjct: 175 EIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/115 (35%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Frame = +1
Query: 1 GNTYD-RGDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPP 165
GN Y G +Q S C C NG T S C C G+TG C I
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI---------- 433
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQSV-GFNGN 324
N C +PC NGGTC +S+ +C+C + GA CQ+P ++ G+S+ G NG+
Sbjct: 434 -NECLSNPCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGESLSGINGS 484
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D + S C+NGG+C +S CICPP + G C + + P++ C+
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS------CQ 185
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC N+ +++C CP G C
Sbjct: 186 NGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 35.1 bits (77), Expect = 0.28
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Frame = +1
Query: 34 SESCQCENGG-----SCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
++ C NGG SCS+ + C C PGYTG+ L N C HP
Sbjct: 350 TDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS------NICLSHP 403
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C N G C ++ + C C G+ G +C
Sbjct: 404 CLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 132
+I + C+NGG+C + S +C CPP G C ++
Sbjct: 175 EIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/115 (35%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Frame = +1
Query: 1 GNTYD-RGDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPP 165
GN Y G +Q S C C NG T S C C G+TG C I
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI---------- 433
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQSV-GFNGN 324
N C +PC NGGTC +S+ +C+C + GA CQ+P ++ G+S+ G NG+
Sbjct: 434 -NECLSNPCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGESLSGINGS 484
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D + S C+NGG+C +S CICPP + G C + + P++ C+
Sbjct: 132 DKKVCSSNPCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS------CQ 185
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC N+ +++C CP G C
Sbjct: 186 NGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 35.1 bits (77), Expect = 0.28
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Frame = +1
Query: 34 SESCQCENGG-----SCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
++ C NGG SCS+ + C C PGYTG+ L N C HP
Sbjct: 350 TDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS------NICLSHP 403
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C N G C ++ + C C G+ G +C
Sbjct: 404 CLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 132
+I + C+NGG+C + S +C CPP G C ++
Sbjct: 175 EIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin
B12 receptor protein.
Length = 3494
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/115 (35%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Frame = +1
Query: 1 GNTYD-RGDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPP 165
GN Y G +Q S C C NG T S C C G+TG C I
Sbjct: 255 GNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI---------- 304
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQSV-GFNGN 324
N C +PC NGGTC +S+ +C+C + GA CQ+P ++ G+S+ G NG+
Sbjct: 305 -NECLSNPCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGESLSGINGS 355
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D + S C+NGG+C +S CICPP + G C + + P++ C+
Sbjct: 3 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS------CQ 56
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC N+ +++C CP G C
Sbjct: 57 NGGTCV---NTMGSYSCHCPPETYGPQC 81
Score = 35.1 bits (77), Expect = 0.28
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Frame = +1
Query: 34 SESCQCENGG-----SCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
++ C NGG SCS+ + C C PGYTG+ L N C HP
Sbjct: 221 TDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS------NICLSHP 274
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C N G C ++ + C C G+ G +C
Sbjct: 275 CLN-GQC---IDTVSGYFCKCDSGWTGVNC 300
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 132
+I + C+NGG+C + S +C CPP G C ++
Sbjct: 46 EIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 84
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/115 (35%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Frame = +1
Query: 1 GNTYD-RGDIQASESC---QCENGGSCSTESTN-CICPPGYTGSYCETRIASYLMSPPPP 165
GN Y G +Q S C C NG T S C C G+TG C I
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENI---------- 433
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLEL-GQSV-GFNGN 324
N C +PC NGGTC +S+ +C+C + GA CQ+P ++ G+S+ G NG+
Sbjct: 434 -NECLSNPCLNGGTCVDGVDSF---SCECTRLWTGALCQVPQQVCGESLSGINGS 484
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D + S C+NGG+C +S CICPP + G C + + P++ C+
Sbjct: 132 DKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLS------CQ 185
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
NGGTC N+ +++C CP G C
Sbjct: 186 NGGTCV---NTMGSYSCHCPPETYGPQC 210
Score = 35.1 bits (77), Expect = 0.28
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Frame = +1
Query: 34 SESCQCENGG-----SCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP 189
++ C NGG SCS+ + C C PGYTG+ L N C HP
Sbjct: 350 TDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLS------NICLSHP 403
Query: 190 CRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C N G C ++ + C C G+ G +C
Sbjct: 404 CLN-GQC---IDTVSGYFCKCDSGWTGVNC 429
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETR 132
+I + C+NGG+C + S +C CPP G C ++
Sbjct: 175 EIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
>Y14330-1|CAA74706.1| 1223|Homo sapiens jagged2 protein protein.
Length = 1223
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 453 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDECASSPCHSGGLCEDL 501
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLEL 297
+ + H C CP G++G C++ ++L
Sbjct: 502 ADGF--H-CHCPQGFSGPLCEVDVDL 524
Score = 50.8 bits (116), Expect = 5e-06
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 301 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 349
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+ + C CP G++G +C
Sbjct: 350 PSGF---ECHCPSGWSGPTC 366
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + Q ++ C NGG+C S ++ C CPPG+ GS C S
Sbjct: 691 GKTCHSREFQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------S 739
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC S + +C C G+ G +C
Sbjct: 740 CLPNPCVNGGTCV---GSGASFSCICRDGWEGRTC 771
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 745 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 792
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
+W C+C G+AG C++ ++ QS
Sbjct: 793 VNWFR--CECAPGFAGPDCRINIDECQS 818
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 489 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 536
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++ C CP + G +C +P E
Sbjct: 537 --YNLEGDYYCACPDDFGGKNCSVPRE 561
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A S C NGGSC + C CP G++G C + ++ C+ +PC GG
Sbjct: 334 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCASA----------DIDECASNPCAAGG 383
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQM 285
TC + + C CP + GA+CQ+
Sbjct: 384 TCVDQVDGF---ECICPEQWVGATCQL 407
Score = 48.8 bits (111), Expect = 2e-05
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 783 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 830
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
N + C CP G AG CQ + G+S G +
Sbjct: 831 INGYR---CSCPPGRAGPRCQEVIGFGRSCWSRGTPF 864
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 591 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 639
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+++ C CP G+ G C
Sbjct: 640 VDAF---RCFCPSGWEGELC 656
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/97 (29%), Positives = 39/97 (40%), Gaps = 2/97 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T DI S C GG+C + CICP + G+ C+ N
Sbjct: 363 GPTCASADIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DANE 411
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
C PC N +CK N + CDC G+ G +C +
Sbjct: 412 CEGKPCLNAFSCK---NLIGGYYCDCIPGWKGINCHI 445
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 616 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 664
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC + G C N + C C G+ G +C
Sbjct: 665 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 694
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 228
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 269 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 314
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP GY+G +C+
Sbjct: 315 ---YRCTCPDGYSGRNCE 329
>BC027939-1|AAH27939.1| 600|Homo sapiens SNED1 protein protein.
Length = 600
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ A +S C++GG C + C+CP + G +CET +PC PC
Sbjct: 64 EVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCET-----------VSDPCFSSPCG 112
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
G C S H+C C +GY G C L
Sbjct: 113 GRGYCLASNGS---HSCTCKVGYTGEDCAKEL 141
Score = 51.6 bits (118), Expect = 3e-06
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGGSC + C CP G+ G +CET V+ C PC++GG C+
Sbjct: 35 CRNGGSCRNLPGAYVCRCPAGFVGVHCETE-----------VDACDSSPCQHGGRCESGG 83
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
+++ C CP + G C+ + S G GY
Sbjct: 84 GAYL---CVCPESFFGYHCETVSDPCFSSPCGGRGY 116
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 513 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 546
Score = 44.0 bits (99), Expect = 6e-04
Identities = 17/40 (42%), Positives = 23/40 (57%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C HPCRNGG+C RN + C CP G+ G C+ ++
Sbjct: 30 CRAHPCRNGGSC---RNLPGAYVCRCPAGFVGVHCETEVD 66
Score = 33.9 bits (74), Expect = 0.64
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 518 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKSFPVWEGGVC 573
>AF111170-2|AAD15562.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDECASSPCHSGGLCEDL 516
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLEL 297
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + Q ++ C NGG+C S ++ C CPPG+ GS C S
Sbjct: 706 GKTCHSREFQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------S 754
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC S + +C C G+ G +C
Sbjct: 755 CLPNPCVNGGTCV---GSGASFSCICRDGWEGRTC 786
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.8 bits (111), Expect = 2e-05
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
N + C CP G AG CQ + G+S G +
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRSCWSRGTPF 879
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQM 285
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C GG+C + CICP + G+ C+ N C PC
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DANECEGKPCL 433
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
N +CK N + CDC G+ G +C +
Sbjct: 434 NAFSCK---NLIGGYYCDCIPGWKGINCHI 460
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 228
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
>AF029779-1|AAB84216.1| 1200|Homo sapiens hJAG2.del-E6 protein.
Length = 1200
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 430 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 478
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLEL 297
+ + H C CP G++G C++ ++L
Sbjct: 479 ADGF--H-CHCPQGFSGPLCEVDVDL 501
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + Q ++ C NGG+C S ++ C CPPG+ GS C S
Sbjct: 668 GKTCHSREFQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------S 716
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC S + +C C G+ G +C
Sbjct: 717 CLPNPCVNGGTCV---GSGASFSCICRDGWEGRTC 748
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 769
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
+W C+C G+AG C++ ++ QS
Sbjct: 770 VNWFR--CECAPGFAGPDCRINIDECQS 795
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 466 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 513
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++ C CP + G +C +P E
Sbjct: 514 --YNLEGDYYCACPDDFGGKNCSVPRE 538
Score = 48.8 bits (111), Expect = 2e-05
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 760 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 807
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
N + C CP G AG CQ + G+S G +
Sbjct: 808 INGYR---CSCPPGRAGPRCQEVIGFGRSCWSRGTPF 841
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 2/107 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C GG+C + CICP + G+ C+ VN C C+
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQL-----------DVNDCR-GQCQ 432
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
+GGTCK N + C CP G+ G C++ + S + G E
Sbjct: 433 HGGTCKDLVNGYQ---CVCPRGFGGRHCELERDKCASSPCHSGGLCE 476
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQM 285
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 568 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 616
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+++ C CP G+ G C
Sbjct: 617 VDAF---RCFCPSGWEGELC 633
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 593 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 641
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC + G C N + C C G+ G +C
Sbjct: 642 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 671
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 228
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
>AF029778-1|AAB84215.1| 1238|Homo sapiens Jagged2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 516
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLEL 297
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + Q ++ C NGG+C S ++ C CPPG+ GS C S
Sbjct: 706 GKTCHSREFQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------S 754
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC S + +C C G+ G +C
Sbjct: 755 CLPNPCVNGGTCV---GSGASFSCICRDGWEGRTC 786
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.8 bits (111), Expect = 2e-05
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
N + C CP G AG CQ + G+S G +
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRSCWSRGTPF 879
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQM 285
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 228
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 39.9 bits (89), Expect = 0.010
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 2/107 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D E C N SC C C PG+ G C VN C C+
Sbjct: 423 DANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHIN-----------VNDCR-GQCQ 470
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
+GGTCK N + C CP G+ G C++ + S + G E
Sbjct: 471 HGGTCKDLVNGYQ---CVCPRGFGGRHCELERDKCASSPCHSGGLCE 514
>AF020201-1|AAB71189.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 516
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLEL 297
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + Q ++ C NGG+C S ++ C CPPG+ GS C S
Sbjct: 706 GKTCHSREFQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------S 754
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC S + +C C G+ G +C
Sbjct: 755 CLPNPCVNGGTCV---GSGASFSCICRDGWEGRTC 786
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.8 bits (111), Expect = 2e-05
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
N + C CP G AG CQ + G+S G +
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRSCWSRGTPF 879
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQM 285
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 228
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/107 (28%), Positives = 41/107 (38%), Gaps = 2/107 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D+ E C N SC C C PG+ G C VN C C+
Sbjct: 423 DVNDCEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHIN-----------VNDCR-GQCQ 470
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
+GGTCK N + C CP G+ G C++ + S + G E
Sbjct: 471 HGGTCKDLVNGYQ---CVCPRGFGGRHCELERDKCASSPCHSGGLCE 514
>AF003521-1|AAB61285.1| 1238|Homo sapiens Jagged 2 protein.
Length = 1238
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 46 QCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
QC++GG+C C+CP G+ G +CE + C+ PC +GG C+
Sbjct: 468 QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-----------RDKCASSPCHSGGLCEDL 516
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLEL 297
+ + H C CP G++G C++ ++L
Sbjct: 517 ADGF--H-CHCPQGFSGPLCEVDVDL 539
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C + C CP GY+G CE + C+ +PC NGG+C
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKA-----------EHACTSNPCANGGSCHEV 365
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLE 294
+ + C CP G++G +C + ++
Sbjct: 366 PSGF---ECHCPSGWSGPTCALDID 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Frame = +1
Query: 1 GNTYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNP 174
G T + Q ++ C NGG+C S ++ C CPPG+ GS C S
Sbjct: 706 GKTCHSREFQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNS----------S 754
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C +PC NGGTC S + +C C G+ G +C
Sbjct: 755 CLPNPCVNGGTCV---GSGASFSCICRDGWEGRTC 786
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C S S +CIC G+ G C N C+ PC NGG C D
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHN-----------TNDCNPLPCYNGGIC-VDG 807
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQS 306
+W C+C G+AG C++ ++ QS
Sbjct: 808 VNWFR--CECAPGFAGPDCRINIDECQS 833
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Frame = +1
Query: 40 SCQCENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S C +GG C + +C CP G++G CE V+ C PCRNG C
Sbjct: 504 SSPCHSGGLCEDLADGFHCHCPQGFSGPLCEV-----------DVDLCEPSPCRNGARC- 551
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
N ++ C CP + G +C +P E
Sbjct: 552 --YNLEGDYYCACPDDFGGKNCSVPRE 576
Score = 48.8 bits (111), Expect = 2e-05
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 3/97 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG C + N C C PG+ G C I + C PC G TC +
Sbjct: 798 CYNGGIC-VDGVNWFRCECAPGFAGPDCRINI-----------DECQSSPCAYGATCVDE 845
Query: 220 RNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGY 330
N + C CP G AG CQ + G+S G +
Sbjct: 846 INGYR---CSCPPGRAGPRCQEVIGFGRSCWSRGTPF 879
Score = 48.0 bits (109), Expect = 4e-05
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A S C NGGSC + C CP G++G C I + C+ +PC GG
Sbjct: 350 ACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDI-----------DECASNPCAAGG 398
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQM 285
TC + + C CP + GA+CQ+
Sbjct: 399 TCVDQVDGF---ECICPEQWVGATCQL 422
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTE---STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C G C ++ + +CIC G+TG+YC I + C PCRNGGTC +
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFTGTYCHENI-----------DDCLGQPCRNGGTCIDE 654
Query: 220 RNSWMNHTCDCPLGYAGASC 279
+++ C CP G+ G C
Sbjct: 655 VDAF---RCFCPSGWEGELC 671
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
TY +I C NGG+C E + C CP G+ G C+T +P N C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDT-------NP----NDCL 679
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
PC + G C N + C C G+ G +C
Sbjct: 680 PDPCHSRGRCYDLVNDFY---CACDDGWKGKTC 709
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 4/78 (5%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPC-SLHPCRNGGTC---KPDRNS 228
GSC E C C + G C+ + N C S HPC NGGTC +PD+
Sbjct: 285 GSC-VEPWQCNCETNWGGLLCDKDL-----------NYCGSHHPCTNGGTCINAEPDQ-- 330
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C CP GY+G +C+
Sbjct: 331 ---YRCTCPDGYSGRNCE 345
Score = 39.9 bits (89), Expect = 0.010
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 2/107 (1%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
D E C N SC C C PG+ G C VN C C+
Sbjct: 423 DANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHIN-----------VNDCR-GQCQ 470
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVE 336
+GGTCK N + C CP G+ G C++ + S + G E
Sbjct: 471 HGGTCKDLVNGYQ---CVCPRGFGGRHCELERDKCASSPCHSGGLCE 514
>X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA for
the chondroitin sulphate proteoglycan versican, V1
splice-variant; precursor peptide. ).
Length = 2409
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 2111 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 2159
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 2160 NTF---RCLCLPSYVGALCEQDTE 2180
Score = 44.4 bits (100), Expect = 5e-04
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 2101 PGPDRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 2142
>U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein
precursor protein.
Length = 1642
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 1344 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 1392
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 1393 NTF---RCLCLPSYVGALCEQDTE 1413
Score = 43.6 bits (98), Expect = 8e-04
Identities = 16/40 (40%), Positives = 24/40 (60%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 1339 CKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 1375
>U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate
proteoglycan versican V0 splice-variant precursor peptide
protein.
Length = 3396
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 3098 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 3146
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 3147 NTF---RCLCLPSYVGALCEQDTE 3167
Score = 44.4 bits (100), Expect = 5e-04
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 3088 PGPDRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 3129
>J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroitin
sulfate proteoglycan core protein mRNA, 3' end. ).
Length = 688
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 390 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 438
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 439 NTF---RCLCLPSYVGALCEQDTE 459
Score = 44.4 bits (100), Expect = 5e-04
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 380 PGPDRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 421
>D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3)
protein.
Length = 655
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 357 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 405
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 406 NTF---RCLCLPSYVGALCEQDTE 426
Score = 44.4 bits (100), Expect = 5e-04
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +1
Query: 124 ETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
++R +Y P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 338 DSRFDAYCFKRP---DRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 388
>BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein
protein.
Length = 2060
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 1762 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 1810
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 1811 NTF---RCLCLPSYVGALCEQDTE 1831
Score = 44.4 bits (100), Expect = 5e-04
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 1752 PGPDRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 1793
>AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate
proteoglycan 2 (versican) variant protein.
Length = 3410
Score = 52.4 bits (120), Expect = 2e-06
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG+C T+ C C PGY+G CE + C +PCRNG TC
Sbjct: 3112 CLNGGTCYPTETSYVCTCVPGYSGDQCEL-----------DFDECHSNPCRNGATCVDGF 3160
Query: 223 NSWMNHTCDCPLGYAGASCQMPLE 294
N++ C C Y GA C+ E
Sbjct: 3161 NTF---RCLCLPSYVGALCEQDTE 3181
Score = 44.4 bits (100), Expect = 5e-04
Identities = 17/45 (37%), Positives = 26/45 (57%)
Frame = +1
Query: 160 PPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
P + C ++PC NGGTC P S++ C C GY+G C++ +
Sbjct: 3102 PGPDRCKMNPCLNGGTCYPTETSYV---CTCVPGYSGDQCELDFD 3143
>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
receptor related protein-deleted in tumor protein.
Length = 4599
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Frame = +1
Query: 22 DIQASESCQ--CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
D +SC+ CENGG C C C P Y+G CE VN CS +
Sbjct: 4210 DSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCE-------------VNHCSNY 4256
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C+NGGTC P + TC C LG+ G +C
Sbjct: 4257 -CQNGGTCVP--SVLGRPTCSCALGFTGPNC 4284
Score = 36.3 bits (80), Expect = 0.12
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG+C + N C C P YTG C+ + H C N +C
Sbjct: 4293 CQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCH--------------HYCVNSESCTIG 4338
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
+ + C CP Y G C++
Sbjct: 4339 DDG--SXECVCPTRYEGPKCEV 4358
>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
lipoprotein-related protein 1B variant protein.
Length = 1720
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Frame = +1
Query: 22 DIQASESCQ--CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH 186
D +SC+ CENGG C C C P Y+G CE VN CS +
Sbjct: 1331 DSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCE-------------VNHCSNY 1377
Query: 187 PCRNGGTCKPDRNSWMNHTCDCPLGYAGASC 279
C+NGGTC P + TC C LG+ G +C
Sbjct: 1378 -CQNGGTCLP--SVLGRPTCSCALGFTGPNC 1405
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C+NGG+C + N C C P YTG C+ + H C N +C
Sbjct: 1414 CQNGGTCIVTAGNQPYCHCQPEYTGDRCQYYVCH--------------HYCVNSESCTIG 1459
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
+ + C CP Y G C++
Sbjct: 1460 DDGSVE--CVCPTRYEGPKCEV 1479
>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related precursor
(AA -19 to 4525) protein.
Length = 4544
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 46 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 4203 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 4248
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ TC CP G+ G C
Sbjct: 4249 SPSGMP--TCRCPTGFTGPKC 4267
Score = 37.1 bits (82), Expect = 0.069
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Frame = +1
Query: 19 GDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
GD + C C NGG+C+ + C CP G+TG C ++ C+
Sbjct: 4228 GDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV-------------CAG 4274
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C N TC ++ + C C G+ G CQ
Sbjct: 4275 Y-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 4304
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIAS 141
C NGGSC+ S C CPP TG CE + S
Sbjct: 4381 CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 4414
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 4276 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 4321
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
+ + C C + G+ C++
Sbjct: 4322 ADG--SRQCRCTAYFEGSRCEV 4341
>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
lipoprotein-related protein 1 (alpha-2-macroglobulin
receptor) protein.
Length = 4544
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 46 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 4203 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 4248
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ TC CP G+ G C
Sbjct: 4249 SPSGMP--TCRCPTGFTGPKC 4267
Score = 37.1 bits (82), Expect = 0.069
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Frame = +1
Query: 19 GDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
GD + C C NGG+C+ + C CP G+TG C ++ C+
Sbjct: 4228 GDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV-------------CAG 4274
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C N TC ++ + C C G+ G CQ
Sbjct: 4275 Y-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 4304
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIAS 141
C NGGSC+ S C CPP TG CE + S
Sbjct: 4381 CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 4414
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 4276 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 4321
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
+ + C C + G+ C++
Sbjct: 4322 ADG--SRQCRCTAYFEGSRCEV 4341
>BC150275-1|AAI50276.1| 1642|Homo sapiens neurexin 2 protein.
Length = 1642
Score = 51.6 bits (118), Expect = 3e-06
Identities = 61/217 (28%), Positives = 90/217 (41%), Gaps = 24/217 (11%)
Frame = +1
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCP-LGYAGASC---QMPLELGQSVGFNGNGYVELPASL 351
+PC NGG C + CDC G+ G C + P+E + N G E A+
Sbjct: 211 NPCANGGLCTVLAPGEVG--CDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATF 268
Query: 352 LRYD----ELASNPAVIALAVHTTNDGVLAYQREGQA--PPNEGDYFLLRIERGFVVLEW 513
+ +L+ NP I + QR G DY L ++ G V L
Sbjct: 269 KGNEFFCYDLSHNP--IQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVI 326
Query: 514 DLGGGLSSIVVDV---PINDGERHQVAA----RLHED-GHAW--LSVDGVDKSAPATGIS 663
+LG G +V+ ND H V R H GHA +SVDG+ + T
Sbjct: 327 NLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQED 386
Query: 664 -NVMNADSNIYIGGIPSWLNIHGYP---GFIGCIENV 762
++ +D YIGG P+ ++ G P F+GC+++V
Sbjct: 387 YTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDV 423
Score = 44.8 bits (101), Expect = 3e-04
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 1/162 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDC-PLGYAGASCQMPLELGQSVGFNGNGYVELPASL 351
C+ PCRNGG C R W CDC G+ G C+ + + ++G+ Y+++
Sbjct: 663 CASAPCRNGGVC---REGWNRFICDCIGTGFLGRVCEREATV---LSYDGSMYMKIMLPN 716
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
+ E A + ++ ++ + RE D L ++ G + L +LG G
Sbjct: 717 AMHTE-AEDVSLRFMSQRAYGLMMATTSRE------SADTLRLELDGGQMKLTVNLGKGP 769
Query: 532 SSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATG 657
++ +ND E H V + LSVD V G
Sbjct: 770 ETLFAGHKLNDNEWHTVRV-VRRGKSLQLSVDNVTVEGQMAG 810
Score = 41.9 bits (94), Expect = 0.002
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLG-GGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKS 642
DYF + + G + L D+G GG+ +NDGE V DG S+ +S
Sbjct: 521 DYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVD--FQRDGRKG-SISVNSRS 577
Query: 643 AP--ATGISNVMNADSNIYIGGIP 708
P ATG S +++ +S +Y+GG+P
Sbjct: 578 TPFLATGDSEILDLESELYLGGLP 601
Score = 40.7 bits (91), Expect = 0.006
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Frame = +1
Query: 457 NEGDYFLLRIERGFVVLEWDLGGGLSSIV--VDVPINDGERHQVAARLHEDGHAWLSVDG 630
N D+ ++ + +G++ +DLG G S + D P+ND + H V L +D
Sbjct: 921 NGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS 980
Query: 631 VDKSAPATGISNVMNADSNIYIGGIPS--WLN----IHGYPGFIGCIENVE 765
+ + G N ++ +YIGG+ + N + GF GC+ +V+
Sbjct: 981 RTVTQHSNGARN-LDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVD 1030
Score = 31.1 bits (67), Expect = 4.5
Identities = 16/59 (27%), Positives = 29/59 (49%)
Frame = +1
Query: 532 SSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
+++ +D P+ D H V + L+VDG ++A M S++++GGIP
Sbjct: 99 ATLQLDTPVADDRWHMVLLT-RDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIP 156
>AK123000-1|BAC85516.1| 1176|Homo sapiens 3 (HIVEP3). protein.
Length = 1176
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Frame = +1
Query: 49 CENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
C +G C + + C C PG+ G CE I + C+ PC +G TC
Sbjct: 76 CHHGALCVPQGPDPNGFRCYCVPGFQGPRCELDI-----------DECASRPCHHGATC- 123
Query: 214 PDRNSWMNHTCDCPLGYAGASCQMPLE 294
RN + C CPLGYAG +C+ ++
Sbjct: 124 --RNLADRYECHCPLGYAGVTCETEVD 148
Score = 50.8 bits (116), Expect = 5e-06
Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
DI S C +G +C + C CP GY G CET V+ C+ PC
Sbjct: 108 DIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCETE-----------VDECASAPCL 156
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
+G +C S+ C C GY G CQ+ L+ QS
Sbjct: 157 HGASCLDGVGSF---RCVCAPGYGGTRCQLDLDECQS 190
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 3/90 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C +G SC S C+C PGY G+ C+ + + C PC
Sbjct: 146 EVDECASAPCLHGASCLDGVGSFRCVCAPGYGGTRCQLDL-----------DECQSQPCA 194
Query: 196 NGGTCKPDRNSWMNHTCDCP-LGYAGASCQ 282
+GGTC N + CDC GY G C+
Sbjct: 195 HGGTCHDLVNGF---RCDCAGTGYEGTHCE 221
Score = 47.6 bits (108), Expect = 5e-05
Identities = 24/65 (36%), Positives = 32/65 (49%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CPPG+ G+ C V+ C+ PC NGG C+ N + C CP GYA
Sbjct: 306 CHCPPGFEGADCGVE-----------VDECASRPCLNGGHCQDLPNGFQ---CHCPDGYA 351
Query: 268 GASCQ 282
G +C+
Sbjct: 352 GPTCE 356
Score = 47.2 bits (107), Expect = 6e-05
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 2/92 (2%)
Frame = +1
Query: 22 DIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
++ S C NGG C C CP GY G CE V+ C PC
Sbjct: 320 EVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCE-----------EDVDECLSDPCL 368
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
+GGTC ++ + C CP + G C + L
Sbjct: 369 HGGTCS---DTVAGYICRCPETWGGRDCSVQL 397
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 10/122 (8%)
Frame = +1
Query: 7 TYDRGDIQASESCQCENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCS 180
T+ ++ S CE+ SC S C+C PGY+G CE SP C
Sbjct: 218 THCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 181 LH--PCRNGGT--CKPDRNSWMNHT---CDCPLGYAGASCQMPL-ELGQSVGFNGNGYVE 336
P GG P S+ + C CP G+ GA C + + E NG +
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPCLNGGHCQD 337
Query: 337 LP 342
LP
Sbjct: 338 LP 339
Score = 39.9 bits (89), Expect = 0.010
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Frame = +1
Query: 88 CICPPGYTGSYCE-TRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGY 264
C P G+ C+ T Y P P C+ PC +G C P C C G+
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEP-RGCATQPCHHGALCVPQGPDPNGFRCYCVPGF 100
Query: 265 AGASCQMPLE 294
G C++ ++
Sbjct: 101 QGPRCELDID 110
Score = 38.7 bits (86), Expect = 0.023
Identities = 16/39 (41%), Positives = 20/39 (51%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
CS PC NGGTC +W + C CP + G +C L
Sbjct: 811 CSPDPCFNGGTCLV---TWNDFHCTCPANFTGPTCAQQL 846
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 2/80 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C + G+C ++ C C PG+ G CE V+PC PC G C
Sbjct: 1065 CLHDGACRDLFDAFACACGPGWEGPRCEAH-----------VDPCHSAPCAR-GRCHTHP 1112
Query: 223 NSWMNHTCDCPLGYAGASCQ 282
+ C CP G+ G C+
Sbjct: 1113 DG--RFECRCPPGFGGPRCR 1130
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPP-VNPCSLHPCRNGGTC 210
C NGG+C + +C CP +TG C A L P P + P + +G C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTC----AQQLWCPGQPCLPPATCEEVPDGFVC 868
>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-related
protein protein.
Length = 4544
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 46 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 4203 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 4248
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ TC CP G+ G C
Sbjct: 4249 SPSGMP--TCRCPTGFTGPKC 4267
Score = 37.1 bits (82), Expect = 0.069
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Frame = +1
Query: 19 GDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
GD + C C NGG+C+ + C CP G+TG C ++ C+
Sbjct: 4228 GDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV-------------CAG 4274
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C N TC ++ + C C G+ G CQ
Sbjct: 4275 Y-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 4304
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIAS 141
C NGGSC+ S C CPP TG CE + S
Sbjct: 4381 CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 4414
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 4276 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 4321
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
+ + C C + G+ C++
Sbjct: 4322 ADG--SRQCRCTAYFEGSRCEV 4341
>AB209498-1|BAD92735.1| 2359|Homo sapiens low density
lipoprotein-related protein 1 variant protein.
Length = 2359
Score = 51.6 bits (118), Expect = 3e-06
Identities = 31/81 (38%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 46 QCENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
QC NGGSC + C C P YTG CE ++ C H CRNGGTC
Sbjct: 2018 QCFNGGSCFLNARRQPKCRCQPRYTGDKCE-------------LDQCWEH-CRNGGTCAA 2063
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
+ TC CP G+ G C
Sbjct: 2064 SPSGMP--TCRCPTGFTGPKC 2082
Score = 37.1 bits (82), Expect = 0.069
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Frame = +1
Query: 19 GDIQASESC--QCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSL 183
GD + C C NGG+C+ + C CP G+TG C ++ C+
Sbjct: 2043 GDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQV-------------CAG 2089
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C N TC ++ + C C G+ G CQ
Sbjct: 2090 Y-CANNSTCTVNQGN--QPQCRCLPGFLGDRCQ 2119
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 3/34 (8%)
Frame = +1
Query: 49 CENGGSCSTEST---NCICPPGYTGSYCETRIAS 141
C NGGSC+ S C CPP TG CE + S
Sbjct: 2196 CSNGGSCTMNSKMMPECQCPPHMTGPRCEEHVFS 2229
Score = 32.3 bits (70), Expect = 2.0
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N +C+ N C C PG+ G C+ R CS + C N GTC+
Sbjct: 2091 CANNSTCTVNQGNQPQCRCLPGFLGDRCQYR-------------QCSGY-CENFGTCQMA 2136
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
+ + C C + G+ C++
Sbjct: 2137 ADG--SRQCRCTAYFEGSRCEV 2156
>AB023138-1|BAA76765.2| 1658|Homo sapiens KIAA0921 protein protein.
Length = 1658
Score = 51.6 bits (118), Expect = 3e-06
Identities = 61/217 (28%), Positives = 90/217 (41%), Gaps = 24/217 (11%)
Frame = +1
Query: 184 HPCRNGGTCKPDRNSWMNHTCDCP-LGYAGASC---QMPLELGQSVGFNGNGYVELPASL 351
+PC NGG C + CDC G+ G C + P+E + N G E A+
Sbjct: 227 NPCANGGLCTVLAPGEVG--CDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATF 284
Query: 352 LRYD----ELASNPAVIALAVHTTNDGVLAYQREGQA--PPNEGDYFLLRIERGFVVLEW 513
+ +L+ NP I + QR G DY L ++ G V L
Sbjct: 285 KGNEFFCYDLSHNP--IQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVI 342
Query: 514 DLGGGLSSIVVDV---PINDGERHQVAA----RLHED-GHAW--LSVDGVDKSAPATGIS 663
+LG G +V+ ND H V R H GHA +SVDG+ + T
Sbjct: 343 NLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQED 402
Query: 664 -NVMNADSNIYIGGIPSWLNIHGYP---GFIGCIENV 762
++ +D YIGG P+ ++ G P F+GC+++V
Sbjct: 403 YTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDV 439
Score = 44.8 bits (101), Expect = 3e-04
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 1/162 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDC-PLGYAGASCQMPLELGQSVGFNGNGYVELPASL 351
C+ PCRNGG C R W CDC G+ G C+ + + ++G+ Y+++
Sbjct: 679 CASAPCRNGGVC---REGWNRFICDCIGTGFLGRVCEREATV---LSYDGSMYMKIMLPN 732
Query: 352 LRYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGL 531
+ E A + ++ ++ + RE D L ++ G + L +LG G
Sbjct: 733 AMHTE-AEDVSLRFMSQRAYGLMMATTSRE------SADTLRLELDGGQMKLTVNLGKGP 785
Query: 532 SSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATG 657
++ +ND E H V + LSVD V G
Sbjct: 786 ETLFAGHKLNDNEWHTVRV-VRRGKSLQLSVDNVTVEGQMAG 826
Score = 41.9 bits (94), Expect = 0.002
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLG-GGLSSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKS 642
DYF + + G + L D+G GG+ +NDGE V DG S+ +S
Sbjct: 537 DYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVD--FQRDGRKG-SISVNSRS 593
Query: 643 AP--ATGISNVMNADSNIYIGGIP 708
P ATG S +++ +S +Y+GG+P
Sbjct: 594 TPFLATGDSEILDLESELYLGGLP 617
Score = 40.7 bits (91), Expect = 0.006
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 8/111 (7%)
Frame = +1
Query: 457 NEGDYFLLRIERGFVVLEWDLGGGLSSIV--VDVPINDGERHQVAARLHEDGHAWLSVDG 630
N D+ ++ + +G++ +DLG G S + D P+ND + H V L +D
Sbjct: 937 NGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS 996
Query: 631 VDKSAPATGISNVMNADSNIYIGGIPS--WLN----IHGYPGFIGCIENVE 765
+ + G N ++ +YIGG+ + N + GF GC+ +V+
Sbjct: 997 RTVTQHSNGARN-LDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVD 1046
Score = 31.1 bits (67), Expect = 4.5
Identities = 16/59 (27%), Positives = 29/59 (49%)
Frame = +1
Query: 532 SSIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
+++ +D P+ D H V + L+VDG ++A M S++++GGIP
Sbjct: 115 ATLQLDTPVADDRWHMVLLT-RDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIP 172
>AK074075-1|BAB84901.1| 522|Homo sapiens FLJ00146 protein protein.
Length = 522
Score = 50.8 bits (116), Expect = 5e-06
Identities = 28/89 (31%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Frame = +1
Query: 31 ASESCQCENGGSCSTESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
A +S C++GG C + C+CP + G +CET +PC PC G
Sbjct: 2 ACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCET-----------VSDPCFSSPCGGRG 50
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C S H+C C +GY G C L
Sbjct: 51 YCLASNGS---HSCTCKVGYTGEDCAKEL 76
Score = 45.6 bits (103), Expect = 2e-04
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQM 285
CS +PC+NGGTC P ++ H+CDC G+ G C++
Sbjct: 448 CSENPCQNGGTCVPGADA---HSCDCGPGFKGRRCEL 481
Score = 34.3 bits (75), Expect = 0.49
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
C+NGG+C ++ +C C PG+ G CE + P GG C
Sbjct: 453 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 508
>BX537434-1|CAD97676.1| 236|Homo sapiens hypothetical protein
protein.
Length = 236
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 268 GASCQ 282
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 200 TGDFTFECNC 209
>BC090943-1|AAH90943.1| 249|Homo sapiens NOTCH2NL protein protein.
Length = 249
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 43 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 93
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 94 TC--HMLSRDTYECTCQVGFTGKECQ 117
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 9 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 55
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 56 QAMLGKATCRCASGFTGEDCQ 76
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 89 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 136
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 137 ANQF---SCKCLTGFTGQKCE 154
Score = 41.5 bits (93), Expect = 0.003
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 166 CQHGGICLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 212
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 213 TGDFTFECNC 222
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GG C
Sbjct: 127 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGIC--- 172
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 173 LNLPGSYQCQCLQGFTGQYC 192
>BC084572-1|AAH84572.1| 343|Homo sapiens NOTCH2NL protein protein.
Length = 343
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 137 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 187
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 188 TC--HMLSRDTYECTCQVGFTGKECQ 211
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G+ G YC+ R +PC + C+NGGTC
Sbjct: 103 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA- 149
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 150 QAMLGKATCRCASGFTGEDCQ 170
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 183 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 230
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 231 ANQF---SCKCLTGFTGQKCE 248
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 221 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 266
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 267 LNLPGSYQCQCLQGFTGQYC 286
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 260 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 306
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 307 TGDFTFECNC 316
>BC065219-1|AAH65219.2| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 268 GASCQ 282
G CQ
Sbjct: 59 GEDCQ 63
Score = 41.5 bits (93), Expect = 0.003
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGICLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 200 TGDFTFECNC 209
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GG C
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGIC--- 159
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
>BC019835-1|AAH19835.1| 236|Homo sapiens Notch homolog 2 N-terminal
like protein protein.
Length = 236
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 268 GASCQ 282
G CQ
Sbjct: 59 GEDCQ 63
Score = 41.5 bits (93), Expect = 0.003
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGICLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 200 TGDFTFECNC 209
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GG C
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGIC--- 159
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
>BC010154-1|AAH10154.3| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 268 GASCQ 282
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 200 TGDFTFECNC 209
>AL592307-2|CAH73994.1| 230|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 230
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 268 GASCQ 282
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 200 TGDFTFECNC 209
>AL592307-1|CAH73993.1| 236|Homo sapiens Notch homolog 2
(Drosophila) N-terminal like protein.
Length = 236
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 30 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 80
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 81 TC--HMLSRDTYECTCQVGFTGKECQ 104
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 76 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 123
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 124 ANQF---SCKCLTGFTGQKCE 141
Score = 45.2 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 30/65 (46%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C CP G+ G YC+ R +PC + C+NGGTC + TC C G+
Sbjct: 12 CKCPEGFLGEYCQHR------------DPCEKNRCQNGGTCVA-QAMLGKATCRCASGFT 58
Query: 268 GASCQ 282
G CQ
Sbjct: 59 GEDCQ 63
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 114 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 159
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 160 LNLPGSYQCQCLQGFTGQYC 179
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 153 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 199
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 200 TGDFTFECNC 209
>AK075065-1|BAC11381.1| 269|Homo sapiens protein ( Homo sapiens
cDNA FLJ90584 fis, clone PLACE1000740, highly similar to
Neurogenic locus notch homolog protein 2 precursor. ).
Length = 269
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C N G C T C CP G++G YC+ R +PC + C+NGGTC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFSGEYCQHR------------DPCEKNRCQNGGTCVA- 81
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
+ TC C G+ G CQ
Sbjct: 82 QAMLGKATCRCASGFTGEDCQ 102
Score = 50.0 bits (114), Expect = 9e-06
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 37 ESCQCENGGSCSTES----TNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
E +C+NGG+C ++ C C G+TG C+ Y S P V+ PC NGG
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQ-----YSTSHPCFVS----RPCLNGG 119
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASCQ 282
TC S + C C +G+ G CQ
Sbjct: 120 TC--HMLSRDTYECTCQVGFTGKECQ 143
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Frame = +1
Query: 49 CENGGSC---STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG+C S ++ C C G+TG C+ A C HPC NG TC
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA------------CLSHPCANGSTCTTV 162
Query: 220 RNSWMNHTCDCPLGYAGASCQ 282
N + +C C G+ G C+
Sbjct: 163 ANQF---SCKCLTGFTGQKCE 180
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSL-HPCRNGGTCKPD 219
C NG +C+T + +C C G+TG CET VN C + C++GGTC
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCET-----------DVNECDIPGHCQHGGTC--- 198
Query: 220 RNSWMNHTCDCPLGYAGASC 279
N ++ C C G+ G C
Sbjct: 199 LNLPGSYQCQCLQGFTGQYC 218
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +1
Query: 49 CENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C++GG+C S C C G+TG YC++ PC+ PC NGGTC+ +
Sbjct: 192 CQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYV-----------PCAPSPCVNGGTCR--Q 238
Query: 223 NSWMNHTCDC 252
C+C
Sbjct: 239 TGDFTFECNC 248
>X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase
protein.
Length = 1138
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/78 (30%), Positives = 32/78 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C +GG C C+CPPG+TG+ CE + CR C PD
Sbjct: 231 CLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPD--- 287
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C C G+ G+ CQ
Sbjct: 288 --PYGCSCGSGWRGSQCQ 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/28 (53%), Positives = 20/28 (71%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
CQC+NGG+C S C+CP G+ G +CE
Sbjct: 319 CQCQNGGTCDRFS-GCVCPSGWHGVHCE 345
Score = 38.3 bits (85), Expect = 0.030
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRN 225
C C + C C G+ GS C+ A P C L C+NGGTC DR
Sbjct: 278 CRGLTFCLPDPYGCSCGSGWRGSQCQEACA-----PGHFGADCRLQCQCQNGGTC--DRF 330
Query: 226 SWMNHTCDCPLGYAGASCQ 282
S C CP G+ G C+
Sbjct: 331 S----GCVCPSGWHGVHCE 345
>BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/78 (30%), Positives = 32/78 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C +GG C C+CPPG+TG+ CE + CR C PD
Sbjct: 231 CLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPD--- 287
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C C G+ G+ CQ
Sbjct: 288 --PYGCSCGSGWRGSQCQ 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/28 (53%), Positives = 20/28 (71%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
CQC+NGG+C S C+CP G+ G +CE
Sbjct: 319 CQCQNGGTCDRFS-GCVCPSGWHGVHCE 345
Score = 38.3 bits (85), Expect = 0.030
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRN 225
C C + C C G+ GS C+ A P C L C+NGGTC DR
Sbjct: 278 CRGLTFCLPDPYGCSCGSGWRGSQCQEACA-----PGHFGADCRLQCQCQNGGTC--DRF 330
Query: 226 SWMNHTCDCPLGYAGASCQ 282
S C CP G+ G C+
Sbjct: 331 S----GCVCPSGWHGVHCE 345
>AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/78 (30%), Positives = 32/78 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C +GG C C+CPPG+TG+ CE + CR C PD
Sbjct: 231 CLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPD--- 287
Query: 229 WMNHTCDCPLGYAGASCQ 282
+ C C G+ G+ CQ
Sbjct: 288 --PYGCSCGSGWRGSQCQ 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 15/28 (53%), Positives = 20/28 (71%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCE 126
CQC+NGG+C S C+CP G+ G +CE
Sbjct: 319 CQCQNGGTCDRFS-GCVCPSGWHGVHCE 345
Score = 38.3 bits (85), Expect = 0.030
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGGTCKPDRN 225
C C + C C G+ GS C+ A P C L C+NGGTC DR
Sbjct: 278 CRGLTFCLPDPYGCSCGSGWRGSQCQEACA-----PGHFGADCRLQCQCQNGGTC--DRF 330
Query: 226 SWMNHTCDCPLGYAGASCQ 282
S C CP G+ G C+
Sbjct: 331 S----GCVCPSGWHGVHCE 345
>AL136322-1|CAI16644.1| 674|Homo sapiens crumbs homolog 1
(Drosophila) protein.
Length = 674
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 1/197 (0%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLL 354
C PC++ G C N W+++ CDC Y G +C G+ + GYV +
Sbjct: 57 CESQPCQSRGRCI---NLWLSYQCDCHRPYEGPNCLREYVAGRFGQDDSTGYV-----IF 108
Query: 355 RYDELASNPAVIALAVHTTNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
DE + +++ V T L E + Y + +ERG + + L
Sbjct: 109 TLDESYGDTISLSMFVRTLQPSGLLLALEN----STYQYIRVWLERGRLAM---LTPNSP 161
Query: 535 SIVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIPSW 714
+VV +NDG H ++ ++ + L + + + D IYIGG+P
Sbjct: 162 KLVVKFVLNDGNVHLISLKI-KPYKIELYQSSQNLGFISASTWKIEKGDV-IYIGGLPDK 219
Query: 715 LNIHGYPGFI-GCIENV 762
GF GCI++V
Sbjct: 220 QETELNGGFFKGCIQDV 236
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 2/96 (2%)
Frame = +1
Query: 25 IQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+ S C +GG+C S +C CP G++G +CE I + C +PC +
Sbjct: 521 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI-----------DECFSNPCIH 569
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQS 306
G C DR + + C C GY G +C++ ++ QS
Sbjct: 570 -GNCS-DRVA--AYHCTCEPGYTGVNCEVDIDNCQS 601
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Frame = +1
Query: 61 GSCSTE--STNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWM 234
G+CS + +C C PGYTG CE I + C H C NG TC N
Sbjct: 570 GNCSDRVAAYHCTCEPGYTGVNCEVDIDN-----------CQSHQCANGATCISHTN--- 615
Query: 235 NHTCDCPLGYAGASCQ 282
++C C + G C+
Sbjct: 616 GYSCLCFGNFTGKFCR 631
Score = 39.9 bits (89), Expect = 0.010
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSC--STESTNCICPPGYTGSYC-ETRIASYLMSPPPPVNPCSLHPC 192
DI +S QC NG +C T +C+C +TG +C ++R+ S + N + C
Sbjct: 595 DIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCG-----NEKTNLTC 649
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGYAG 270
NGG C + C C G+ G
Sbjct: 650 YNGGNCTEFQTEL---KCMCRPGFTG 672
Score = 38.7 bits (86), Expect = 0.023
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
N C +PC NGG C + W + +C CP +G +C+
Sbjct: 270 NSCKSNPCHNGGVC---HSRWDDFSCSCPALTSGKACE 304
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 GDIQASESCQCENGGSCST--ESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
GD + +S C NGG C + + +C CP +G CE V C PC
Sbjct: 268 GD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE------------VQWCGFSPC 314
Query: 193 RNGGTCKP 216
+G C+P
Sbjct: 315 PHGAQCQP 322
Score = 32.3 bits (70), Expect = 2.0
Identities = 12/26 (46%), Positives = 17/26 (65%), Gaps = 2/26 (7%)
Frame = +1
Query: 49 CENGGSCSTESTN--CICPPGYTGSY 120
C NGG+C+ T C+C PG+TG +
Sbjct: 649 CYNGGNCTEFQTELKCMCRPGFTGEW 674
>D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein.
Length = 830
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Frame = +1
Query: 37 ESCQ-----CENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
ESC+ C +G +C ++ +C C PG+ G CE P P
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTGTFGEDCGST 354
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
TC + C C GY G SC GF+GN
Sbjct: 355 CPTCVQGSCDTVTGDCVCSAGYWGPSCNASC----PAGFHGN 392
Score = 30.7 bits (66), Expect = 6.0
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKP 216
GSC T + +C+C GY G C + N CS+ PC G C P
Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCSV-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein.
Length = 830
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Frame = +1
Query: 37 ESCQ-----CENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
ESC+ C +G +C ++ +C C PG+ G CE P P
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTGTFGEDCGST 354
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
TC + C C GY G SC GF+GN
Sbjct: 355 CPTCVQGSCDTVTGDCVCSAGYWGPSCNASC----PAGFHGN 392
Score = 30.7 bits (66), Expect = 6.0
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKP 216
GSC T + +C+C GY G C + N CS+ PC G C P
Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCSV-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor class
F, member 1 protein.
Length = 830
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Frame = +1
Query: 37 ESCQ-----CENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
ESC+ C +G +C ++ +C C PG+ G CE P P
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTGTFGEDCGST 354
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
TC + C C GY G SC GF+GN
Sbjct: 355 CPTCVQGSCDTVTGDCVCSAGYWGPSCNASC----PAGFHGN 392
Score = 30.7 bits (66), Expect = 6.0
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKP 216
GSC T + +C+C GY G C + N CS+ PC G C P
Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCSV-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>BC006425-1|AAH06425.1| 204|Homo sapiens EGFL9 protein protein.
Length = 204
Score = 48.8 bits (111), Expect = 2e-05
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C R
Sbjct: 4 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARC---R 49
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ + C CP GY G +C++ L
Sbjct: 50 DRVHDFDCLCPSGYGGKTCELVL 72
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/38 (39%), Positives = 21/38 (55%)
Frame = +1
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ PC NG TC N + +C CP G+AG C + L+
Sbjct: 1 MRPCANGATCLDGINRF---SCLCPEGFAGRFCTINLD 35
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 42 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 78
>BC000230-1|AAH00230.1| 204|Homo sapiens EGFL9 protein protein.
Length = 204
Score = 48.8 bits (111), Expect = 2e-05
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Frame = +1
Query: 49 CENGGSC--STESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NG +C +C+CP G+ G +C + + C+ PC+ G C R
Sbjct: 4 CANGATCLDGINRFSCLCPEGFAGRFCTINL-----------DDCASRPCQRGARC---R 49
Query: 223 NSWMNHTCDCPLGYAGASCQMPL 291
+ + C CP GY G +C++ L
Sbjct: 50 DRVHDFDCLCPSGYGGKTCELVL 72
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/38 (39%), Positives = 21/38 (55%)
Frame = +1
Query: 181 LHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ PC NG TC N + +C CP G+AG C + L+
Sbjct: 1 MRPCANGATCLDGINRF---SCLCPEGFAGRFCTINLD 35
Score = 30.7 bits (66), Expect = 6.0
Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)
Frame = +1
Query: 49 CENGGSCS--TESTNCICPPGYTGSYCETRIASYLMSPPPP 165
C+ G C +C+CP GY G CE L P PP
Sbjct: 42 CQRGARCRDRVHDFDCLCPSGYGGKTCEL----VLPVPDPP 78
>AK027618-1|BAB55237.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ14712 fis, clone NT2RP3000825, weakly similar to
NEUROGENIC LOCUS NOTCH 3 PROTEIN. ).
Length = 849
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/78 (35%), Positives = 37/78 (47%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C NGGSC+ +T C+CP G+ G +C+ +P PC+NGG C
Sbjct: 689 CLNGGSCNKPNT-CLCPNGFFGEHCQNAFC----------HP----PCKNGGHC------ 727
Query: 229 WMNHTCDCPLGYAGASCQ 282
N+ C C GY G CQ
Sbjct: 728 MRNNVCVCREGYTGRRCQ 745
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/81 (34%), Positives = 34/81 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C NGG C ST C CP G++G C T P L C+NGG C
Sbjct: 753 CMNGGKCVGPST-CSCPSGWSGKRCNT--------------PICLQKCKNGGECIAPS-- 795
Query: 229 WMNHTCDCPLGYAGASCQMPL 291
C CP + G CQ+P+
Sbjct: 796 ----ICHCPSSWEGVRCQIPI 812
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/81 (33%), Positives = 34/81 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C+C GYTG C+ I P C NGG C
Sbjct: 721 CKNGGHCMRNNV-CVCREGYTGRRCQKSICD-------PT-------CMNGGKCVGPS-- 763
Query: 229 WMNHTCDCPLGYAGASCQMPL 291
TC CP G++G C P+
Sbjct: 764 ----TCSCPSGWSGKRCNTPI 780
Score = 40.7 bits (91), Expect = 0.006
Identities = 30/89 (33%), Positives = 38/89 (42%), Gaps = 9/89 (10%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPD-- 219
C++GG C + C CP G+ G CET + C+ H C NGG C PD
Sbjct: 625 CQHGGICLAGNL-CTCPYGFVGPRCETMV-------------CNRH-CENGGQCLTPDIC 669
Query: 220 --RNSWMNHTCD---C-PLGYAGASCQMP 288
+ W TC C P+ G SC P
Sbjct: 670 QCKPGWYGPTCSTALCDPVCLNGGSCNKP 698
Score = 40.3 bits (90), Expect = 0.007
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 8/81 (9%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTN--------CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
+SC C NGGSC ++ C+C PG+ GS CE I+ C +PC
Sbjct: 438 KSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISG-----------CQSNPC 486
Query: 193 RNGGTCKPDRNSWMNHTCDCP 255
G + + +++CDCP
Sbjct: 487 GLGSYI----SGFHSYSCDCP 503
Score = 36.3 bits (80), Expect = 0.12
Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 13/93 (13%)
Frame = +1
Query: 43 CQCENGGSCSTESTN-CICPPGYTGSYCETRIAS-YLMSPPPPVNP--CSLHPCRNGGTC 210
C+ G S + N C C PGY GS C+T + + + P C P G TC
Sbjct: 557 CKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATC 616
Query: 211 KPDR-NSWMNH--------TCDCPLGYAGASCQ 282
+ N H C CP G+ G C+
Sbjct: 617 DEEHCNPPCQHGGICLAGNLCTCPYGFVGPRCE 649
>AB052950-1|BAC02696.1| 744|Homo sapiens SREC-5 protein.
Length = 744
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 35.5 bits (78), Expect = 0.21
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Frame = +1
Query: 25 IQASESC-QCENGGSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+Q + SC +C++ CS ++ +C C PG+ G+ C+ C H CR+
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCP-H-CRH 315
Query: 199 GGTCKPD 219
G C+PD
Sbjct: 316 GEACEPD 322
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052949-1|BAC02695.1| 337|Homo sapiens SREC-4 protein.
Length = 337
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 36.3 bits (80), Expect = 0.12
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 25 IQASESC-QCENGGSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+Q + SC +C++ CS ++ +C C PG+ G+ C+ C H CR+
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCP-H-CRH 315
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAG 270
G C+PD H C G+ G
Sbjct: 316 GEACEPD----TGHCQRCDPGWLG 335
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein.
Length = 569
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Frame = +1
Query: 37 ESCQ-----CENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
ESC+ C +G +C ++ +C C PG+ G CE P P
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTGTFGEDCGST 354
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
TC + C C GY G SC GF+GN
Sbjct: 355 CPTCVQGSCDTVTGDCVCSAGYWGPSCNASC----PAGFHGN 392
Score = 30.7 bits (66), Expect = 6.0
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKP 216
GSC T + +C+C GY G C + N CS+ PC G C P
Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCSV-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052947-1|BAC02693.1| 342|Homo sapiens SREC-2 protein.
Length = 342
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 36.3 bits (80), Expect = 0.12
Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Frame = +1
Query: 25 IQASESC-QCENGGSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
+Q + SC +C++ CS ++ +C C PG+ G+ C+ C H CR+
Sbjct: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCE-QQCP-H-CRH 315
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAG 270
G C+PD H C G+ G
Sbjct: 316 GEACEPD----TGHCQRCDPGWLG 335
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein.
Length = 830
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 7/93 (7%)
Frame = +1
Query: 43 CQCENGGS-CSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP------CRNG 201
CQC + C + C+C PG+ G C R + C+ P C+
Sbjct: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ 222
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
C R S + C CP G+ GA C++P G
Sbjct: 223 CECVRGRCSAASGECTCPPGFRGARCELPCPAG 255
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+ + C+C G CS S C CPPG+ G+ CE + + C C++
Sbjct: 218 ECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAG-SHGVQCAHSCG--RCKHNEP 273
Query: 208 CKPDRNSWMNHTCD-CPLGYAGASCQMP 288
C PD S C+ C G+ G CQ P
Sbjct: 274 CSPDTGS-----CESCEPGWNGTQCQQP 296
Score = 37.5 bits (83), Expect = 0.052
Identities = 21/71 (29%), Positives = 28/71 (39%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C PG+ G++C +R P C PC G C+P + C C
Sbjct: 75 CRCKPGFFGAHCSSRCPGQYWGPDCR-ESC---PCHPHGQCEPATGA-----CQCQADRW 125
Query: 268 GASCQMPLELG 300
GA C+ P G
Sbjct: 126 GARCEFPCACG 136
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 6/102 (5%)
Frame = +1
Query: 37 ESCQ-----CENGGSCSTESTNCI-CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN 198
ESC+ C +G +C ++ +C C PG+ G CE P P
Sbjct: 304 ESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCED---------PCPTGTFGEDCGST 354
Query: 199 GGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGN 324
TC + C C GY G SC GF+GN
Sbjct: 355 CPTCVQGSCDTVTGDCVCSAGYWGPSCNASC----PAGFHGN 392
Score = 30.7 bits (66), Expect = 6.0
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKP 216
GSC T + +C+C GY G C + N CS+ PC G C P
Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHG-----NNCSV-PCECPEGLCHP 407
Score = 30.3 bits (65), Expect = 7.9
Identities = 24/84 (28%), Positives = 29/84 (34%), Gaps = 2/84 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
ESC C G C + C C G+ CE A P C P C+P
Sbjct: 101 ESCPCHPHGQCEPATGACQCQADRWGARCEFPCAC------GPHGRCD--PATGVCHCEP 152
Query: 217 DRNSWMNHTC--DCPLGYAGASCQ 282
W + TC C A A C+
Sbjct: 153 ---GWWSSTCRRPCQCNTAAARCE 173
>AB037723-1|BAA92540.3| 2016|Homo sapiens KIAA1302 protein protein.
Length = 2016
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/99 (34%), Positives = 43/99 (43%), Gaps = 2/99 (2%)
Frame = +1
Query: 46 QCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRN 225
+C G+C C C PG+ G +C IA YL P C G C D N
Sbjct: 10 RCAEHGTC--RDGKCECSPGWNGEHCT--IAHYLDRVVKEGCPGL---CNGNGRCTLDLN 62
Query: 226 SWMNHTCDCPLGYAGASCQMPLE--LGQSVGFNGNGYVE 336
W H C C LG+ GA C +E G S +G+G V+
Sbjct: 63 GW--H-CVCQLGWRGAGCDTSMETACGDSKDNDGDGLVD 98
>Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)
protein.
Length = 3110
Score = 48.4 bits (110), Expect = 3e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----AAINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain protein.
Length = 3110
Score = 48.4 bits (110), Expect = 3e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----AAINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 39.9 bits (89), Expect = 0.010
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGHAWL-SVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + ++ +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANIYIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL050329-2|CAB99359.1| 399|Homo sapiens protein ( Human DNA
sequence from clone RP1-22I17 on chromosome 6q11.1-12
Contains the 3' end of the PHF3 gene for PHD finger
protein 3. ).
Length = 399
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/165 (24%), Positives = 70/165 (42%), Gaps = 3/165 (1%)
Frame = +1
Query: 49 CENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C NGG C+ T +C C P + G+ C ++ C + C + C PD+
Sbjct: 139 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS------------CLNNLCLHQSLCIPDQ 186
Query: 223 NSWMNHTCDCPLGYAGASCQMPLELGQSVGFNGNGYVELPASLLRYDELASNPAVIALAV 402
+ +++C C LG+ G C+ + F GN Y++ R L I+L
Sbjct: 187 S--FSYSCLCTLGWVGRYCENKTSF-STAKFMGNSYIKYIDPNYRMRNLQF--TTISLNF 241
Query: 403 HTT-NDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLS 534
TT +G++ + G A E D+ + + + + +LG +S
Sbjct: 242 STTKTEGLIVWM--GIAQNEENDFLAIGLHNQTLKIAVNLGERIS 284
Score = 34.7 bits (76), Expect = 0.37
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 9/108 (8%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGG--LSSIVVDVPINDGERHQV-AARLHEDGHAWLSVDGVD 636
D+ + + V L ++LG + + V IN H + A R+ +G+ L +DG++
Sbjct: 1 DFLCISLVNSSVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGY--LDLDGIN 58
Query: 637 KSAPATGISNVMNADSNIYIGGIPSW-----LNIHGYP-GFIGCIENV 762
+ A+ + ++ +++ YIGG+ S + I P GF GCI V
Sbjct: 59 VTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQV 106
>AK098809-1|BAC05419.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ25943 fis, clone JTH10559. ).
Length = 320
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG T +C CPPG+ G+ C P N C NGG C DR
Sbjct: 36 CQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGP----NCSQECRCHNGGLC--DR-- 87
Query: 229 WMNHTCDCPLGYAGASCQMPLELGQ 303
C C GY G C+ +G+
Sbjct: 88 -FTGQCRCAPGYTGDRCREECPVGR 111
Score = 47.6 bits (108), Expect = 5e-05
Identities = 27/83 (32%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
S+ C+C NGG C + C C PGYTG C PV C C
Sbjct: 74 SQECRCHNGGLCDRFTGQCRCAPGYTGDRCREEC---------PVGRFG-QDCAETCDCA 123
Query: 214 PDRNSW-MNHTCDCPLGYAGASC 279
PD + N C C G+ G C
Sbjct: 124 PDARCFPANGACLCEHGFTGDRC 146
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/57 (38%), Positives = 25/57 (43%)
Frame = +1
Query: 37 ESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
E C C +GG C S C C PGYTG +C + PPP P P G T
Sbjct: 207 EHCLCLHGGVCQATSGLCQCAPGYTGPHCASLC-------PPPRRPRRFLPQAAGET 256
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/82 (28%), Positives = 33/82 (40%)
Frame = +1
Query: 34 SESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCK 213
+E+C C C + C+C G+TG C R+ PC+ + +C
Sbjct: 117 AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDR-EHSLSCH 175
Query: 214 PDRNSWMNHTCDCPLGYAGASC 279
P MN C C G+AG C
Sbjct: 176 P-----MNGECSCLPGWAGLHC 192
Score = 39.1 bits (87), Expect = 0.017
Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLH-PCRNGG 204
QA +C E+ SC + C C PG+ G +C P C H C +GG
Sbjct: 161 QAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGP-----GCQEHCLCLHGG 215
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASC 279
C+ + C C GY G C
Sbjct: 216 VCQA-----TSGLCQCAPGYTGPHC 235
Score = 36.7 bits (81), Expect = 0.091
Identities = 16/41 (39%), Positives = 21/41 (51%)
Frame = +1
Query: 178 SLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLELG 300
S HPC+NGG + + S C CP G+ G C +P G
Sbjct: 32 STHPCQNGGVFQTPQGS-----CSCPPGWMGTICSLPCPEG 67
>M59832-1|AAA63215.1| 1130|Homo sapiens merosin protein.
Length = 1130
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 800 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 855
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 856 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 911
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 407 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 466
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 467 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 499
>M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.
Length = 1609
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Frame = +1
Query: 28 QASESCQCE----NGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-- 189
Q E C C G C + C C PG TG +CE ++ P PC HP
Sbjct: 930 QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEG 989
Query: 190 -----CRNGGTCKPDRNSWMNHTCD-CPLGY 264
C++ G C+ R ++ + CD C Y
Sbjct: 990 SLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 231
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 232 MNHTCDCPLGYAGASCQ 282
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.7 bits (86), Expect = 0.023
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +1
Query: 4 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 174
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNVETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +1
Query: 37 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 192
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.
Length = 1609
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Frame = +1
Query: 28 QASESCQCE----NGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-- 189
Q E C C G C + C C PG TG +CE ++ P PC HP
Sbjct: 930 QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEG 989
Query: 190 -----CRNGGTCKPDRNSWMNHTCD-CPLGY 264
C++ G C+ R ++ + CD C Y
Sbjct: 990 SLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 231
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 232 MNHTCDCPLGYAGASCQ 282
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.7 bits (86), Expect = 0.023
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +1
Query: 4 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 174
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNVETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +1
Query: 37 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 192
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>BC018037-1|AAH18037.1| 379|Homo sapiens WNT inhibitory factor 1
protein.
Length = 379
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/88 (35%), Positives = 37/88 (42%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+A+ S C NGG+C CICPPG G CE ++ C PCRNGG
Sbjct: 243 KANCSTTCFNGGTCFYPG-KCICPPGLEGEQCE-------------ISKCP-QPCRNGGK 287
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C C C GY G C P+
Sbjct: 288 CIG------KSKCKCSKGYQGDLCSKPV 309
Score = 36.7 bits (81), Expect = 0.091
Identities = 26/77 (33%), Positives = 32/77 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C NGG C+ E C CP G+ G +CE L +P C NGG C
Sbjct: 186 CRNGGFCN-ERRICECPDGFHGPHCE----KALCTP----------RCMNGGLCVTP--- 227
Query: 229 WMNHTCDCPLGYAGASC 279
C CP G+ G +C
Sbjct: 228 ---GFCICPPGFYGVNC 241
>AY358344-1|AAQ88710.1| 379|Homo sapiens WIF-1 protein.
Length = 379
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/88 (35%), Positives = 37/88 (42%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+A+ S C NGG+C CICPPG G CE ++ C PCRNGG
Sbjct: 243 KANCSTTCFNGGTCFYPG-KCICPPGLEGEQCE-------------ISKCP-QPCRNGGK 287
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C C C GY G C P+
Sbjct: 288 CIG------KSKCKCSKGYQGDLCSKPV 309
Score = 36.7 bits (81), Expect = 0.091
Identities = 26/77 (33%), Positives = 32/77 (41%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C NGG C+ E C CP G+ G +CE L +P C NGG C
Sbjct: 186 CRNGGFCN-ERRICECPDGFHGPHCE----KALCTP----------RCMNGGLCVTP--- 227
Query: 229 WMNHTCDCPLGYAGASC 279
C CP G+ G +C
Sbjct: 228 ---GFCICPPGFYGVNC 241
>AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Frame = +1
Query: 28 QASESCQCE----NGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-- 189
Q E C C G C + C C PG TG +CE ++ P PC HP
Sbjct: 930 QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEG 989
Query: 190 -----CRNGGTCKPDRNSWMNHTCD-CPLGY 264
C++ G C+ R ++ + CD C Y
Sbjct: 990 SLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 231
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 232 MNHTCDCPLGYAGASCQ 282
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.3 bits (85), Expect = 0.030
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +1
Query: 4 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 174
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNIETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +1
Query: 37 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 192
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (merosin,
congenital muscular dystrophy) protein.
Length = 3122
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 2780 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 2835
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 2836 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 2891
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Frame = +1
Query: 37 ESCQCENG------GSCSTESTNC-ICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR 195
+ CQC + GSC + S +C IC PG TG YCE Y N C C
Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKN-CQPCRCN 921
Query: 196 NGGTCKPDRNSWMNHTCDCPLGYAGASC 279
GG+ +S C+C G C
Sbjct: 922 AGGSFSEVCHS-QTGQCECRANVQGQRC 948
Score = 38.3 bits (85), Expect = 0.030
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 2387 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 2446
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNI 723
AT S + AD IY GG+P+ N+
Sbjct: 2447 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNL 2479
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 1555
Query: 274 SC 279
C
Sbjct: 1556 KC 1557
Score = 33.5 bits (73), Expect = 0.85
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCET 129
GS + C CPPGYTGS CE+
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCES 737
Score = 33.5 bits (73), Expect = 0.85
Identities = 25/83 (30%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Frame = +1
Query: 43 CQCENGGSCS---TESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRN-GGTC 210
C C + GS S ES C C PG TG C+ Y C+ C + G C
Sbjct: 967 CNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQE---GGCTACECSHLGNNC 1023
Query: 211 KPDRNSWMNHTCDCPLGYAGASC 279
P C CP G C
Sbjct: 1024 DPKTG-----RCICPPNTIGEKC 1041
Score = 33.5 bits (73), Expect = 0.85
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Frame = +1
Query: 40 SCQCEN-GGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKP 216
+C+C + G +C ++ CICPP G C ++ A C C G+
Sbjct: 1013 ACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTG-CKACNCSTVGSLDF 1070
Query: 217 DRNSWMNHTCDCPLGYAGASC 279
N C+C ++GA C
Sbjct: 1071 QCNV-NTGQCNCHPKFSGAKC 1090
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 2/66 (3%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCR-NGGTCKPDRNSWMNHTC-DCPLGYA 267
CP GYTG CE Y P P C C N P ++ +C C G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 268 GASCQM 285
G C++
Sbjct: 895 GRYCEL 900
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 1380 CDCPLGYSGLSCE 1392
>AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 48.0 bits (109), Expect = 4e-05
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 12/91 (13%)
Frame = +1
Query: 28 QASESCQCE----NGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHP-- 189
Q E C C G C + C C PG TG +CE ++ P PC HP
Sbjct: 930 QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEG 989
Query: 190 -----CRNGGTCKPDRNSWMNHTCD-CPLGY 264
C++ G C+ R ++ + CD C Y
Sbjct: 990 SLSLQCKDDGRCE-CREGFVGNRCDQCEENY 1019
Score = 45.2 bits (102), Expect = 3e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Frame = +1
Query: 61 GSCSTESTNCICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCR-NGGTCKPDRNSW 231
G +T +C CP GY G +CE ++ Y P P +PC L C + TC P+
Sbjct: 681 GVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETG-- 738
Query: 232 MNHTCDCPLGYAGASCQ 282
C+C AG C+
Sbjct: 739 ---VCNCRDNTAGPHCE 752
Score = 38.3 bits (85), Expect = 0.030
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 3/96 (3%)
Frame = +1
Query: 4 NTYDRGDIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNP 174
N + G+ +A SC C GS ST+ + C C PG G C+ + P
Sbjct: 385 NFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
CS P + C + C C G +C+
Sbjct: 445 CSCDPSGSIDECNIETG-----RCVCKDNVEGFNCE 475
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Frame = +1
Query: 37 ESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPVNPCSLHPC 192
+ C C G SC+ T+ C CP G TG CE Y P PV C L C
Sbjct: 771 QPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQC 830
>AF122922-1|AAD25402.1| 379|Homo sapiens Wnt inhibitory factor-1
protein.
Length = 379
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/88 (35%), Positives = 37/88 (42%)
Frame = +1
Query: 28 QASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGT 207
+A+ S C NGG+C CICPPG G CE ++ C PCRNGG
Sbjct: 243 KANCSTTCFNGGTCFYPG-KCICPPGLEGEQCE-------------ISKCP-QPCRNGGK 287
Query: 208 CKPDRNSWMNHTCDCPLGYAGASCQMPL 291
C C C GY G C P+
Sbjct: 288 CIG------KSKCKCSKGYQGDLCSKPV 309
Score = 37.1 bits (82), Expect = 0.069
Identities = 28/85 (32%), Positives = 35/85 (41%)
Frame = +1
Query: 25 IQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGG 204
+QA C NGG C+ E C CP G+ G +CE L +P C NGG
Sbjct: 178 LQAECPGGCRNGGFCN-ERRICECPDGFHGPHCE----KALCTP----------RCMNGG 222
Query: 205 TCKPDRNSWMNHTCDCPLGYAGASC 279
C C CP G+ G +C
Sbjct: 223 LCVTP------GFCICPPGFYGVNC 241
>AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein.
Length = 1321
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E+ C +GG+C+ T C C G+ G CE I + C PC NGGTC
Sbjct: 1013 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDI-----------DDCLCSPCENGGTC 1061
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ N ++ C C Y G+ C+ E
Sbjct: 1062 IDEVNGFV---CLCLPSYGGSFCEKDTE 1086
Score = 40.3 bits (90), Expect = 0.007
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+PC +PC +GGTC + N M + C C G+AG +C++ ++
Sbjct: 1010 DPCENNPCLHGGTC--NANGTM-YGCSCDQGFAGENCEIDID 1048
Score = 38.7 bits (86), Expect = 0.023
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
DI CENGG+C E C+C P Y GS+CE
Sbjct: 1046 DIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCE 1082
>AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS
protein.
Length = 315
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E+ C +GG+C+ T C C G+ G CE I + C PC NGGTC
Sbjct: 7 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDI-----------DDCLCSPCENGGTC 55
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ N ++ C C Y G+ C+ E
Sbjct: 56 IDEVNGFV---CLCLPSYGGSFCEKDTE 80
Score = 40.3 bits (90), Expect = 0.007
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+PC +PC +GGTC + N M + C C G+AG +C++ ++
Sbjct: 4 DPCENNPCLHGGTC--NANGTM-YGCSCDQGFAGENCEIDID 42
Score = 38.7 bits (86), Expect = 0.023
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
DI CENGG+C E C+C P Y GS+CE
Sbjct: 40 DIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCE 76
>AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein
protein.
Length = 1335
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Frame = +1
Query: 37 ESCQCENGGSCSTEST--NCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC 210
E+ C +GG+C+ T C C G+ G CE I + C PC NGGTC
Sbjct: 1027 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDI-----------DDCLCSPCENGGTC 1075
Query: 211 KPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+ N ++ C C Y G+ C+ E
Sbjct: 1076 IDEVNGFV---CLCLPSYGGSFCEKDTE 1100
Score = 40.3 bits (90), Expect = 0.007
Identities = 16/42 (38%), Positives = 27/42 (64%)
Frame = +1
Query: 169 NPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+PC +PC +GGTC + N M + C C G+AG +C++ ++
Sbjct: 1024 DPCENNPCLHGGTC--NANGTM-YGCSCDQGFAGENCEIDID 1062
Score = 38.7 bits (86), Expect = 0.023
Identities = 17/37 (45%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN--CICPPGYTGSYCE 126
DI CENGG+C E C+C P Y GS+CE
Sbjct: 1060 DIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCE 1096
>AB208922-1|BAD92159.1| 1853|Homo sapiens laminin alpha 2 subunit
precursor variant protein.
Length = 1853
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Frame = +1
Query: 361 DELASNPAVIALAVHT-TNDGVLAYQREGQAPPNEGDYFLLRIERGFVVLEWDLGGGLSS 537
D N I L V T G+L Y A N D+ +++ G +DLG G +
Sbjct: 1511 DTKVKNRLTIELEVRTEAESGLLFYM----ARINHADFATVQLRNGLPYFSYDLGSGDTH 1566
Query: 538 IVVDVPINDGERHQVAARLHEDGHAWLSVDGVDKSAPATGISNVMNADSNIYIGGIP 708
++ INDG+ H++ + L VDG + +++++ +Y+GG+P
Sbjct: 1567 TMIPTKINDGQWHKIKI-MRSKQEGILYVDGASNRTISPKKADILDVVGMLYVGGLP 1622
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Frame = +1
Query: 466 DYFLLRIERGFVVLEWDLGGGLSSIVVDVPINDGE-RHQVAARLHEDGH-AWLSVDGVDK 639
D+ + + G + + +DLG G++S+V + NDG+ + +R+ + + + + +D +
Sbjct: 1122 DFMSVELTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQE 1181
Query: 640 SAPATGISN-----VMNADSNIYIGGIPSWLNIH---GYPGFIGCIENVE 765
AT S + AD IY GG+P+ N+ + GC++++E
Sbjct: 1182 ENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLRPEVNLKKYSGCLKDIE 1231
Score = 36.7 bits (81), Expect = 0.091
Identities = 21/62 (33%), Positives = 23/62 (37%)
Frame = +1
Query: 94 CPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGA 273
CP GY G YCE Y SP P C C G+ P + C C G G
Sbjct: 232 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL-PVPCDPVTGFCTCRPGATGR 290
Query: 274 SC 279
C
Sbjct: 291 KC 292
Score = 31.9 bits (69), Expect = 2.6
Identities = 10/13 (76%), Positives = 12/13 (92%)
Frame = +1
Query: 244 CDCPLGYAGASCQ 282
CDCPLGY+G SC+
Sbjct: 115 CDCPLGYSGLSCE 127
>AL137007-1|CAC10575.2| 199|Homo sapiens novel EGF-like domain
containing protein protein.
Length = 199
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 7/98 (7%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN-----CICPPGYTGSYCETRIASYLMSPPPPVNPCSL- 183
+I +S C NGG C EST C+CPP YTG +C R N C L
Sbjct: 15 EINECDSDPCMNGGLCH-ESTIPGQFVCLCPPLYTGQFCHQR-----------YNLCDLL 62
Query: 184 -HPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
+PCRN TC ++ N C C + G +C++ ++
Sbjct: 63 HNPCRNNSTCLALVDA--NQHCICREEFEGKNCEIDVK 98
Score = 43.6 bits (98), Expect = 8e-04
Identities = 27/88 (30%), Positives = 38/88 (43%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNG 201
D++ C++ G C N PG++GS CE I N CS PC+N
Sbjct: 96 DVKDCLFLSCQDYGDCEDMVNNF--RPGFSGSLCEIEI-----------NECSSEPCKNN 142
Query: 202 GTCKPDRNSWMNHTCDCPLGYAGASCQM 285
GTC N + C+C Y G C++
Sbjct: 143 GTCVDLTNRFF---CNCEPEYHGPFCEL 167
Score = 34.7 bits (76), Expect = 0.37
Identities = 22/70 (31%), Positives = 24/70 (34%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYA 267
C C G+TG C I N C PC NGG C + C CP Y
Sbjct: 1 CECTSGWTGQNCSEEI-----------NECDSDPCMNGGLCH-ESTIPGQFVCLCPPLYT 48
Query: 268 GASCQMPLEL 297
G C L
Sbjct: 49 GQFCHQRYNL 58
Score = 34.3 bits (75), Expect = 0.49
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Frame = +1
Query: 22 DIQASESCQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPC 192
+I S C+N G+C + TN C C P Y G +CE VN C + PC
Sbjct: 130 EINECSSEPCKNNGTC-VDLTNRFFCNCEPEYHGPFCEL-----------DVNKCKISPC 177
Query: 193 RNGGTCKPDRNSWMNHTCDCPLGY 264
+ C + + C C GY
Sbjct: 178 LDEENCVYRTD---GYNCLCAPGY 198
>X73902-1|CAA52108.1| 1193|Homo sapiens nicein protein.
Length = 1193
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 168
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 169 NPCSLHPCRN 198
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 240
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 241 TCDCPLGY 264
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +1
Query: 13 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 165
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 2.6
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +1
Query: 43 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 150
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>U31201-1|AAC50457.1| 1193|Homo sapiens laminin gamma2 chain
protein.
Length = 1193
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 168
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 169 NPCSLHPCRN 198
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 240
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 241 TCDCPLGY 264
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +1
Query: 13 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 165
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 2.6
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +1
Query: 43 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 150
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>U31200-1|AAC50456.1| 1111|Homo sapiens alternatively spliced
laminin gamma2 chain protein.
Length = 1111
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 168
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 169 NPCSLHPCRN 198
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 240
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 241 TCDCPLGY 264
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +1
Query: 13 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 165
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 2.6
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +1
Query: 43 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 150
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>BC113378-1|AAI13379.1| 1111|Homo sapiens laminin, gamma 2 protein.
Length = 1111
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 168
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 169 NPCSLHPCRN 198
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 240
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 241 TCDCPLGY 264
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +1
Query: 13 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 165
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 2.6
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +1
Query: 43 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 150
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>BC112286-1|AAI12287.1| 1111|Homo sapiens laminin, gamma 2 protein.
Length = 1111
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 168
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 169 NPCSLHPCRN 198
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 240
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 241 TCDCPLGY 264
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +1
Query: 13 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 165
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 2.6
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +1
Query: 43 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 150
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>BC039143-1|AAH39143.1| 740|Homo sapiens FAT2 protein protein.
Length = 740
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG CS T C CPP ++G +CE + C+ PC GGTC
Sbjct: 347 CLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN-----------CTFAPCLEGGTC--- 392
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
S +C+CP Y G C+M
Sbjct: 393 ILSPKGASCNCPHPYTGDRCEM 414
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/40 (32%), Positives = 19/40 (47%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
CS + C NGG C + + C CP ++G C+ E
Sbjct: 342 CSQNTCLNGGKCSWTHGA--GYVCKCPPQFSGKHCEQGRE 379
>AL354953-2|CAH70980.1| 1193|Homo sapiens laminin, gamma 2 protein.
Length = 1193
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Frame = +1
Query: 13 DRGDIQASESCQCENGGSCS----TESTNCI-CPPGYTGSYCETRIASYLMSP---PPPV 168
D D ++ + C C NG SCS TE C CPPG TG+ CE Y P PV
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 169 NPCSLHPCRN 198
PC C N
Sbjct: 512 RPCQPCQCNN 521
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Frame = +1
Query: 88 CICPPGYTGSYCETRIASYLMSPP--PPVNPCSLHPCRNGGTCKPDRNSWMN-------H 240
CICP GY G +C+ + Y P C C+ GG C PD +
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDPDTGDCYSGDENPDIE 441
Query: 241 TCDCPLGY 264
DCP+G+
Sbjct: 442 CADCPIGF 449
Score = 41.9 bits (94), Expect = 0.002
Identities = 21/81 (25%), Positives = 32/81 (39%)
Frame = +1
Query: 43 CQCENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDR 222
C C+ GG+C ++ +C C + P P C PC NG +C
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDP-RSCKPCPCHNGFSCSVMP 474
Query: 223 NSWMNHTCDCPLGYAGASCQM 285
+ +CP G GA C++
Sbjct: 475 ETEEVVCNNCPPGVTGARCEL 495
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 9/99 (9%)
Frame = +1
Query: 13 DRGDIQASESCQCENG------GSCSTESTNCI-CPPGYTGSYCETRIASYLMSP--PPP 165
+ G ++ + CQC N G+C + C+ C G YC+ A Y P P P
Sbjct: 507 EHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNP 566
Query: 166 VNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQ 282
+ C C G+ S + TC C G+ G +C+
Sbjct: 567 ADKCRACNCNPMGSEPVGCRS--DGTCVCKPGFGGPNCE 603
Score = 31.9 bits (69), Expect = 2.6
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Frame = +1
Query: 43 CQCENGGSCSTESTN---CICPPGYTGSYCETRIASYLM 150
C C + GS S N C C PG TG+ C+ + + M
Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHM 122
>AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 protein.
Length = 4349
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG CS T C CPP ++G +CE + C+ PC GGTC
Sbjct: 3956 CLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN-----------CTFAPCLEGGTC--- 4001
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
S +C+CP Y G C+M
Sbjct: 4002 ILSPKGASCNCPHPYTGDRCEM 4023
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/40 (32%), Positives = 19/40 (47%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
CS + C NGG C + + C CP ++G C+ E
Sbjct: 3951 CSQNTCLNGGKCSWTHGA--GYVCKCPPQFSGKHCEQGRE 3988
>AB177851-1|BAD66829.1| 573|Homo sapiens KIAA0811 splice variant 1
protein.
Length = 573
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG CS T C CPP ++G +CE + C+ PC GGTC
Sbjct: 180 CLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN-----------CTFAPCLEGGTC--- 225
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
S +C+CP Y G C+M
Sbjct: 226 ILSPKGASCNCPHPYTGDRCEM 247
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/40 (32%), Positives = 19/40 (47%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
CS + C NGG C + + C CP ++G C+ E
Sbjct: 175 CSQNTCLNGGKCSWTHGA--GYVCKCPPQFSGKHCEQGRE 212
>AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein.
Length = 1123
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG CS T C CPP ++G +CE + C+ PC GGTC
Sbjct: 730 CLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN-----------CTFAPCLEGGTC--- 775
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
S +C+CP Y G C+M
Sbjct: 776 ILSPKGASCNCPHPYTGDRCEM 797
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/40 (32%), Positives = 19/40 (47%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
CS + C NGG C + + C CP ++G C+ E
Sbjct: 725 CSQNTCLNGGKCSWTHGA--GYVCKCPPQFSGKHCEQGRE 762
>AB011535-1|BAA32463.1| 573|Homo sapiens MEGF1 protein.
Length = 573
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Frame = +1
Query: 49 CENGGSCS-TESTN--CICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPD 219
C NGG CS T C CPP ++G +CE + C+ PC GGTC
Sbjct: 180 CLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGREN-----------CTFAPCLEGGTC--- 225
Query: 220 RNSWMNHTCDCPLGYAGASCQM 285
S +C+CP Y G C+M
Sbjct: 226 ILSPKGASCNCPHPYTGDRCEM 247
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/40 (32%), Positives = 19/40 (47%)
Frame = +1
Query: 175 CSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPLE 294
CS + C NGG C + + C CP ++G C+ E
Sbjct: 175 CSQNTCLNGGKCSWTHGA--GYVCKCPPQFSGKHCEQGRE 212
>BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein
protein.
Length = 1323
Score = 46.4 bits (105), Expect = 1e-04
Identities = 26/77 (33%), Positives = 33/77 (42%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTCKPDRNS 228
C+NGG C + C CP G+ G CE P + PC NGG C
Sbjct: 1228 CQNGGICQRPNA-CSCPEGWMGRLCE--------------EPICILPCLNGGRCVAP--- 1269
Query: 229 WMNHTCDCPLGYAGASC 279
+ CDCP G+ G+ C
Sbjct: 1270 ---YQCDCPPGWTGSRC 1283
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Frame = +1
Query: 49 CENGGSCSTESTNCICPPGYTGSYCETRIASYLMSPPPPVNPCSLHPCRNGGTC-KPDR- 222
C NGG C C CPPG+TGS C T + PC NGG C +P+R
Sbjct: 1260 CLNGGRC-VAPYQCDCPPGWTGSRCHTAVCQ--------------SPCLNGGKCVRPNRC 1304
Query: 223 ---NSWMNHTC 246
+SW H C
Sbjct: 1305 HCLSSWTGHNC 1315
Score = 34.3 bits (75), Expect = 0.49
Identities = 15/45 (33%), Positives = 21/45 (46%)
Frame = +1
Query: 157 PPPVNPCSLHPCRNGGTCKPDRNSWMNHTCDCPLGYAGASCQMPL 291
PP PC+NGG C+ + C CP G+ G C+ P+
Sbjct: 1217 PPICRAVCRFPCQNGGICQ------RPNACSCPEGWMGRLCEEPI 1255
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.317 0.137 0.445
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,964,287
Number of Sequences: 237096
Number of extensions: 3170062
Number of successful extensions: 18797
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 9734
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 15112
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9255747988
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
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