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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= an--0113
         (697 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri...   264   1e-69
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ...   201   2e-50
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA...   200   3e-50
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu...   200   3e-50
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p...   181   1e-44
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R...   178   9e-44
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi...   175   1e-42
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve...   172   8e-42
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1...   171   1e-41
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal...   170   2e-41
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ...   170   2e-41
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13...   170   2e-41
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep...   170   3e-41
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ...   169   4e-41
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|...   169   4e-41
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb...   166   4e-40
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons...   166   5e-40
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18...   165   7e-40
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep...   165   9e-40
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi...   165   1e-39
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ...   164   2e-39
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ...   164   2e-39
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ...   164   2e-39
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|...   163   5e-39
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio...   161   1e-38
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ...   161   1e-38
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta...   161   1e-38
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r...   161   1e-38
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica...   159   6e-38
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt...   159   6e-38
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:...   159   8e-38
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E...   159   8e-38
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+...   158   1e-37
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|...   157   2e-37
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R...   157   2e-37
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor...   156   6e-37
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ...   156   6e-37
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta...   155   7e-37
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n...   155   1e-36
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti...   154   2e-36
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium...   154   2e-36
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac...   153   3e-36
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ...   153   3e-36
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct...   153   4e-36
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ...   153   4e-36
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7...   153   4e-36
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re...   153   4e-36
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:...   152   9e-36
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   152   9e-36
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re...   152   9e-36
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org...   152   9e-36
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   152   9e-36
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ...   151   2e-35
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R...   150   3e-35
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ...   150   3e-35
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A...   149   5e-35
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=...   149   6e-35
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d...   149   6e-35
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   148   1e-34
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;...   147   2e-34
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   147   2e-34
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;...   147   2e-34
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ...   147   2e-34
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7...   147   3e-34
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r...   147   3e-34
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam...   146   3e-34
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin...   146   3e-34
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di...   146   3e-34
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re...   146   6e-34
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste...   146   6e-34
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve...   146   6e-34
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   144   1e-33
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str...   144   2e-33
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria...   144   2e-33
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam...   144   2e-33
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy...   144   2e-33
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ...   143   3e-33
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac...   143   3e-33
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   143   4e-33
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota...   143   4e-33
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt...   142   6e-33
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+...   142   6e-33
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald...   142   6e-33
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   142   7e-33
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li...   141   1e-32
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n...   140   2e-32
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ...   140   2e-32
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or...   140   2e-32
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb...   140   2e-32
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ...   140   2e-32
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ...   140   3e-32
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm...   140   4e-32
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4...   139   5e-32
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27...   138   9e-32
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam...   138   2e-31
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase...   138   2e-31
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ...   137   2e-31
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ...   137   2e-31
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam...   137   3e-31
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...   136   4e-31
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea...   136   4e-31
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti...   136   4e-31
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|...   136   4e-31
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ...   136   5e-31
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct...   136   5e-31
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami...   136   5e-31
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ...   136   5e-31
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ...   136   6e-31
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc...   135   8e-31
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep...   135   8e-31
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac...   135   8e-31
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ...   135   8e-31
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ...   135   1e-30
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB...   135   1e-30
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:...   134   1e-30
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=...   134   1e-30
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam...   134   1e-30
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA...   134   3e-30
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct...   134   3e-30
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=...   133   5e-30
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam...   132   6e-30
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str...   132   6e-30
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ...   132   8e-30
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several...   132   8e-30
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop...   132   1e-29
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E...   132   1e-29
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red...   131   2e-29
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct...   131   2e-29
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ...   131   2e-29
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag...   131   2e-29
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh...   131   2e-29
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea...   131   2e-29
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ...   130   2e-29
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno...   130   2e-29
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=...   130   2e-29
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S...   130   2e-29
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ...   130   3e-29
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=...   130   3e-29
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   130   4e-29
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n...   130   4e-29
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ...   130   4e-29
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;...   129   6e-29
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;...   129   7e-29
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;...   128   1e-28
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   128   1e-28
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar...   128   1e-28
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba...   128   2e-28
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct...   127   2e-28
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled...   127   3e-28
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium...   127   3e-28
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10...   126   4e-28
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li...   126   7e-28
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;...   126   7e-28
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:...   126   7e-28
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl...   126   7e-28
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re...   125   9e-28
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ...   125   1e-27
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta...   125   1e-27
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba...   124   2e-27
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ...   124   2e-27
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop...   124   2e-27
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam...   124   2e-27
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ...   124   3e-27
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci...   123   4e-27
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ...   123   4e-27
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li...   123   5e-27
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam...   123   5e-27
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ...   123   5e-27
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal...   123   5e-27
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red...   122   6e-27
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r...   122   1e-26
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ...   122   1e-26
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil...   121   1e-26
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ...   121   2e-26
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re...   121   2e-26
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ...   120   3e-26
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ...   106   3e-26
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep...   120   4e-26
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r...   120   4e-26
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ...   120   4e-26
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;...   119   8e-26
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l...   119   8e-26
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep...   118   1e-25
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom...   118   1e-25
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve...   118   1e-25
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ...   118   1e-25
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...   118   2e-25
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy...   118   2e-25
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O...   117   2e-25
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r...   117   2e-25
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1...   117   3e-25
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;...   117   3e-25
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;...   116   4e-25
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3...   116   4e-25
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:...   116   6e-25
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ...   116   7e-25
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter...   116   7e-25
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam...   115   1e-24
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob...   115   1e-24
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ...   115   1e-24
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri...   102   2e-24
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ...   114   2e-24
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ...   114   2e-24
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,...   113   4e-24
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ...   113   4e-24
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc...   113   4e-24
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas...   113   5e-24
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101...   112   7e-24
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re...   112   7e-24
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l...   112   7e-24
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str...   112   9e-24
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam...   111   2e-23
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ...   110   3e-23
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec...   110   3e-23
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba...   110   4e-23
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami...   109   5e-23
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re...   109   6e-23
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=...   109   6e-23
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n...   109   6e-23
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc...   109   8e-23
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ...   108   1e-22
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter...   108   1e-22
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-22
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct...   108   1e-22
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1...   107   2e-22
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ...   107   3e-22
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ...   107   3e-22
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...   106   6e-22
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ...   106   6e-22
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ...   105   8e-22
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba...   105   8e-22
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ...   105   8e-22
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc...   105   1e-21
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r...   105   1e-21
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ...   105   1e-21
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ...   105   1e-21
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ...   104   2e-21
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam...   104   2e-21
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la...   104   2e-21
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez...   103   3e-21
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=...   103   4e-21
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ...   103   4e-21
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte...   102   7e-21
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1...   102   7e-21
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik...   102   7e-21
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil...   102   1e-20
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace...   102   1e-20
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo...   102   1e-20
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ...   101   2e-20
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ...   100   3e-20
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ...   100   3e-20
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la...   100   3e-20
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try...   100   7e-20
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri...   100   7e-20
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl...    99   9e-20
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra...    99   1e-19
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac...    98   2e-19
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi...    98   2e-19
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini...    97   4e-19
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act...    96   6e-19
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ...    96   6e-19
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami...    96   6e-19
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam...    96   8e-19
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac...    96   8e-19
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    94   3e-18
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ...    93   4e-18
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami...    93   4e-18
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ...    93   6e-18
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ...    93   6e-18
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep...    93   8e-18
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami...    92   1e-17
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,...    91   2e-17
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium...    91   2e-17
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la...    91   2e-17
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet...    91   2e-17
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere...    90   4e-17
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ...    89   1e-16
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac...    89   1e-16
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v...    89   1e-16
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ...    88   2e-16
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica...    63   2e-16
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap...    87   4e-16
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    87   4e-16
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta...    86   7e-16
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;...    86   9e-16
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc...    85   1e-15
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ...    85   2e-15
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve...    84   4e-15
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta...    83   6e-15
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc...    83   6e-15
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;...    83   6e-15
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez...    83   8e-15
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe...    82   1e-14
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ...    81   2e-14
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam...    81   3e-14
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017...    80   6e-14
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom...    78   2e-13
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter...    77   3e-13
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep...    77   4e-13
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei...    77   4e-13
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054...    76   1e-12
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ...    75   1e-12
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D...    75   1e-12
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc...    74   4e-12
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The...    74   4e-12
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;...    73   5e-12
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ...    73   5e-12
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|...    73   5e-12
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto...    73   9e-12
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep...    72   2e-11
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc...    72   2e-11
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ...    71   3e-11
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam...    70   6e-11
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r...    69   8e-11
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n...    69   1e-10
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    69   1e-10
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th...    69   1e-10
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella...    68   3e-10
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ...    68   3e-10
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ...    66   8e-10
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ...    66   1e-09
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy...    65   1e-09
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n...    65   1e-09
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola...    65   2e-09
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep...    64   2e-09
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ...    64   3e-09
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ...    64   3e-09
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata...    64   3e-09
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|...    64   4e-09
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p...    64   4e-09
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    63   5e-09
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria...    63   7e-09
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob...    63   7e-09
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact...    63   7e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul...    63   7e-09
UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri...    62   1e-08
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa...    62   1e-08
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ...    62   1e-08
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=...    62   1e-08
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|...    62   2e-08
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria...    61   2e-08
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia...    61   2e-08
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    61   3e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3....    61   3e-08
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga...    60   4e-08
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac...    60   4e-08
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid...    60   5e-08
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam...    60   5e-08
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000...    60   7e-08
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep...    59   9e-08
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O...    59   9e-08
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:...    59   9e-08
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ...    59   9e-08
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ...    59   9e-08
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel...    59   1e-07
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    59   1e-07
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy...    59   1e-07
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3...    59   1e-07
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt...    58   2e-07
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep...    58   2e-07
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu...    58   2e-07
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r...    58   2e-07
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam...    58   2e-07
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=...    58   2e-07
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel...    58   3e-07
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ...    58   3e-07
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n...    58   3e-07
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez...    58   3e-07
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket...    57   5e-07
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ...    57   5e-07
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669...    57   5e-07
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei...    57   5e-07
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc...    56   6e-07
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba...    56   6e-07
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy...    56   6e-07
UniRef50_A6VSN1 Cluster: Aldo/keto reductase; n=8; Proteobacteri...    56   6e-07
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu...    56   6e-07
UniRef50_Q2UCK9 Cluster: Predicted oxidoreductases; n=16; Pezizo...    56   6e-07
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap...    56   6e-07
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam...    56   8e-07
UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada...    56   8e-07
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal...    56   8e-07
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms...    56   8e-07
UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam...    56   1e-06
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a...    56   1e-06
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org...    56   1e-06
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ...    55   1e-06
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ...    55   1e-06
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri...    55   1e-06
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi...    55   1e-06
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:...    55   2e-06
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re...    55   2e-06
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga...    54   3e-06
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ...    54   3e-06
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh...    54   3e-06
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:...    54   3e-06
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon...    54   3e-06
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia...    54   3e-06
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;...    54   3e-06
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep...    54   3e-06
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative...    54   3e-06
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ...    54   3e-06
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ...    54   3e-06
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|...    54   4e-06
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p...    54   4e-06
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki...    54   4e-06
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ...    54   4e-06
UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta...    54   4e-06
UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=...    54   4e-06
UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ...    53   6e-06
UniRef50_O43488 Cluster: Aflatoxin B1 aldehyde reductase member ...    53   6e-06
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular...    53   8e-06
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P...    53   8e-06
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:...    53   8e-06
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea...    53   8e-06
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe...    53   8e-06
UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep...    52   1e-05
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob...    52   1e-05
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido...    52   1e-05
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll...    52   1e-05
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    52   1e-05
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ...    52   1e-05
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta...    52   1e-05
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R...    52   1e-05
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;...    52   2e-05
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|...    52   2e-05
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter...    52   2e-05
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina...    52   2e-05
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno...    52   2e-05
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R...    51   2e-05
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu...    51   2e-05
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase...    51   3e-05
UniRef50_Q7UL88 Cluster: DTDP-4-keto-L-6-deoxy-hexose 2,3-reduct...    51   3e-05
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep...    51   3e-05
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid...    51   3e-05
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal...    51   3e-05
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ...    51   3e-05
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|...    51   3e-05
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n...    50   4e-05
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea...    50   4e-05
UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc...    50   5e-05
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R...    50   5e-05
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep...    50   5e-05
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep...    50   5e-05
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ...    50   5e-05
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ...    50   5e-05
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ...    50   5e-05
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami...    50   5e-05
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ...    50   5e-05
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma...    50   7e-05
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam...    50   7e-05
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido...    50   7e-05
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De...    49   1e-04
UniRef50_Q4J031 Cluster: Aldo/keto reductase precursor; n=2; Pse...    49   1e-04
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ...    49   1e-04
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|...    49   1e-04
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ...    49   1e-04
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ...    49   1e-04
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob...    49   1e-04
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001...    49   1e-04
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re...    49   1e-04
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis...    49   1e-04
UniRef50_Q3AD20 Cluster: Oxidoreductase, aldo/keto reductase fam...    49   1e-04
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ...    49   1e-04
UniRef50_Q1NH47 Cluster: Rhizopine catabolism protein; n=7; Prot...    49   1e-04
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s...    49   1e-04
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ...    49   1e-04
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac...    49   1e-04
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ...    49   1e-04
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=...    49   1e-04
UniRef50_UPI00005100E5 Cluster: COG0667: Predicted oxidoreductas...    48   2e-04
UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3; Actinomyc...    48   2e-04
UniRef50_Q0RGG9 Cluster: Putative oxidoreductase; n=1; Frankia a...    48   2e-04
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec...    48   2e-04
UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir...    48   2e-04
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba...    48   2e-04
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi...    48   2e-04
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re...    48   2e-04
UniRef50_Q2P313 Cluster: Voltage-gated potassium channel beta su...    48   2e-04
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter...    48   2e-04
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri...    48   2e-04
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam...    48   2e-04
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep...    48   2e-04
UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib...    48   3e-04
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep...    48   3e-04
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte...    48   3e-04
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep...    48   3e-04
UniRef50_A6WDF5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:...    48   3e-04
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=...    48   3e-04
UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St...    47   4e-04
UniRef50_A3K469 Cluster: Aldo/keto reductase; n=3; Rhodobacterac...    47   4e-04
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma...    47   4e-04
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=...    47   4e-04
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p...    47   5e-04
UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ...    47   5e-04

>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
           Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
           Trichoplusia ni (Cabbage looper)
          Length = 308

 Score =  264 bits (648), Expect = 1e-69
 Identities = 136/222 (61%), Positives = 163/222 (73%), Gaps = 3/222 (1%)
 Frame = +2

Query: 41  ITLTCLLNAAMAV--QAPCIQLNDGNTIPIVALGT-GRGTAKESDSIDEVRQAVYWAIEA 211
           + L  L+NA      +AP  QLNDGN IP +ALGT G G       I +VRQAV WAI+A
Sbjct: 8   VALWALVNAISGEPGKAPLKQLNDGNAIPSLALGTFGFG------DIPKVRQAVLWAIQA 61

Query: 212 GYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLK 391
           GYRHIDTAA+Y +EE+VG+GIA+AI  GLV REELFVTTKLWNDKH R QVVPAL+ESL 
Sbjct: 62  GYRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLT 121

Query: 392 KLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 571
           KLGL Y+DLYLIH P AT  +  P +ID L TW GM++A++LGLA+SIGVSNF+   + R
Sbjct: 122 KLGLSYVDLYLIHSPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDR 181

Query: 572 LVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           L++ S   P +NQIEV+P+ TQE LVA     GI VMAYSPF
Sbjct: 182 LIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPF 223


>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 321

 Score =  201 bits (490), Expect = 2e-50
 Identities = 103/213 (48%), Positives = 142/213 (66%), Gaps = 11/213 (5%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I L+DGN +P++ LGT +G     +  DEV  AV  AI+AGYRH D A+ Y +E ++G+ 
Sbjct: 8   ITLSDGNKVPVLGLGTWQG----GNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKA 63

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 436
           I E I  G+V RE+LFV TK+WND+  ++ VV A + SLKKLGL YIDLYL+H+P     
Sbjct: 64  IQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPI 123

Query: 437 ------IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
                 + T    + D +DY+ETW+GM++  +LGL RSIGVSNFN+ Q+TRL+ ++ I+P
Sbjct: 124 LYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           V+NQIE++    Q+ L   C S  IAV  YSPF
Sbjct: 184 VMNQIELHINLNQKKLREFCASKSIAVTGYSPF 216


>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10458-PA - Nasonia vitripennis
          Length = 569

 Score =  200 bits (487), Expect = 3e-50
 Identities = 100/214 (46%), Positives = 141/214 (65%), Gaps = 11/214 (5%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P +  NDG  +P++ LGT            EV +AV +AIE GYRH+DTA  Y++E+++G
Sbjct: 4   PTVTFNDGYKMPMIGLGTFLSKP------GEVAEAVKYAIEVGYRHVDTAFFYENEKEIG 57

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
             I E I +G + RE++FVTTKLW + H  D+VVPA ++SL+ LG DYIDL+L+H+P A 
Sbjct: 58  SAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAF 117

Query: 446 K------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
           K      P D+   I     DYLETW+GM++ ++ GLARSIG+SNFN+ QI RL+S++ I
Sbjct: 118 KSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKI 177

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +PV NQ+EV     Q+PL+  C+   I V  +SP
Sbjct: 178 KPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSP 211



 Score =  166 bits (403), Expect = 5e-40
 Identities = 90/191 (47%), Positives = 122/191 (63%), Gaps = 9/191 (4%)
 Frame = +2

Query: 149 TAKESDSIDEV-RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 325
           T +E  +I+++ +   Y  +   YRHIDTA +Y +E+ +G  I E I +G V RE+LFVT
Sbjct: 278 TPEEVSTIEKMGKHNKYLILLYRYRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVT 337

Query: 326 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA-----TKPDDSP---DNIDYL 481
           TKL    H   +VVPA ++SL  LGLDYIDLYLIH+PI       K         + DYL
Sbjct: 338 TKLSYYAHKESEVVPACKQSLNDLGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYL 397

Query: 482 ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQ 661
           ETW+GM++ ++ GLARSIGVSNFN+ QITRL+  + I+PV NQ+EV+    Q+ L+  C+
Sbjct: 398 ETWKGMEECKRQGLARSIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCK 457

Query: 662 SLGIAVMAYSP 694
              I V  YSP
Sbjct: 458 KHDITVTGYSP 468


>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
           precursor; n=1; Spodoptera littoralis|Rep:
           3-dehydroecdysone 3beta-reductase precursor - Spodoptera
           littoralis (Egyptian cotton leafworm)
          Length = 345

 Score =  200 bits (487), Expect = 3e-50
 Identities = 98/223 (43%), Positives = 140/223 (62%), Gaps = 3/223 (1%)
 Frame = +2

Query: 38  IITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKES--DSID-EVRQAVYWAIE 208
           I+ L C    +  +  P +++ +   +P +ALGT  G  K     S D ++R  V  AI+
Sbjct: 7   ILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAID 66

Query: 209 AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESL 388
            GYRH DTAA+Y  E +VG+ I   I  G++ RE++F+TTKLWN  H R+QV  A++E+L
Sbjct: 67  LGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETL 126

Query: 389 KKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 568
            K GLDY+DL+L+H+PIA   D S  N DYLETW+  ++  +LG  +SIG+SNFN  Q+ 
Sbjct: 127 NKTGLDYVDLFLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVA 186

Query: 569 RLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
            ++    I+PV  QIEV+P   QE L+ + +  GI VM YSPF
Sbjct: 187 TVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPF 229


>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
           Drosophila melanogaster (Fruit fly)
          Length = 311

 Score =  181 bits (441), Expect = 1e-44
 Identities = 98/212 (46%), Positives = 134/212 (63%), Gaps = 8/212 (3%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           AP I+LN+G  +P + LGT +    ESD+    R A    ++ GYRH+DTA VY++E +V
Sbjct: 5   APTIRLNNGREMPTLGLGTWKSF--ESDAYHSTRHA----LDVGYRHLDTAFVYENEAEV 58

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           GQ I+E IA G+VTREE+FVTTKL    H    V  A + SL  LGL+Y+DLYL+H P+ 
Sbjct: 59  GQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVG 118

Query: 443 TK-PDDSP-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
            K  +DS         ++DYL+TW+ M+    LGL RSIG+SNFNA Q  R+++N  IRP
Sbjct: 119 QKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRP 178

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           V+NQ+E +P   Q  L  H +  G+ + AY P
Sbjct: 179 VVNQVECHPGFQQRQLREHAKRHGLVICAYCP 210


>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
           Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
          Length = 321

 Score =  178 bits (434), Expect = 9e-44
 Identities = 90/217 (41%), Positives = 143/217 (65%), Gaps = 10/217 (4%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNT-IPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQ 247
           MA   P + L+ G   +P++ LGT      + ++   VR+AV  A++ GYRH DTAA+Y 
Sbjct: 1   MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPET---VRKAVTEALKLGYRHFDTAALYN 57

Query: 248 DEEQVGQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 424
            E+ +G  IAEA+  GL+ +R+ELF+T+KLW     R+ V PALQ++LK L L+YID+YL
Sbjct: 58  SEQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYL 117

Query: 425 IHFPIATKPDD------SPD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 580
           IH+P+++KP +        D   +DY   W+ M++ ++LGL ++IGVSNF+  +++ +++
Sbjct: 118 IHWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLA 177

Query: 581 NSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
           N+ + P +NQ+EVNP   Q+ L   C+S GI V+AY+
Sbjct: 178 NAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYA 214


>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
           Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
           sapiens (Human)
          Length = 325

 Score =  175 bits (425), Expect = 1e-42
 Identities = 88/216 (40%), Positives = 135/216 (62%), Gaps = 12/216 (5%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           A C+ L+ G  +P++ LGT +          +V+ AV +A+  GYRHID AA+Y +E ++
Sbjct: 3   ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56

Query: 263 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
           G+ + E +  G  V REELFVT+KLWN KH  + V PAL+++L  L L+Y+DLYL+H+P 
Sbjct: 57  GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116

Query: 440 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 586
           A +  D+P           D+  Y ETW+ ++     GL +++G+SNFN+ QI  ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176

Query: 587 YIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +RP + Q+E +P   Q  L+AHCQ+ G+ V AYSP
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSP 212


>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 323

 Score =  172 bits (418), Expect = 8e-42
 Identities = 96/219 (43%), Positives = 130/219 (59%), Gaps = 11/219 (5%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA++    +LN G +IP +ALGT +       S +EV  AV  AIE GYRHID A +Y +
Sbjct: 1   MAMKQIFCKLNTGASIPAMALGTWQS------SKEEVGNAVRLAIELGYRHIDCAEIYGN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E ++G+ ++E +  G V REELFVT+KLW D H  D V+PA Q +LK L LDY+DLYLIH
Sbjct: 55  EGEIGEALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIH 114

Query: 431 FPIATK-----PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
            P+A K     P    + I          TWQ M+     GL ++IGVSNF+  ++ +L+
Sbjct: 115 IPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLL 174

Query: 578 SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
             + I P  NQ+E++P   QE L   C S GI + AYSP
Sbjct: 175 ETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYSP 213


>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
           GA19341-PA - Drosophila pseudoobscura (Fruit fly)
          Length = 315

 Score =  171 bits (416), Expect = 1e-41
 Identities = 96/217 (44%), Positives = 129/217 (59%), Gaps = 12/217 (5%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           +  P   L+ G  +P+V LGT R         + V QAV  AI+ GYRH D A +Y +E 
Sbjct: 1   MSTPSFLLSSGRNMPMVGLGTWRSPP------EVVAQAVKDAIDIGYRHFDCAHIYGNEL 54

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
            VG  I E I  GLVTR+ELF+T+KLWN  H  + V  A + SL+ LG+DY+DLYL+H+P
Sbjct: 55  HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114

Query: 437 IATKPDDS-----PD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 580
           +A K  D+     PD       +IDYL+TW+ M+D    GL  +IGVSNFN  QI RL+ 
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174

Query: 581 NSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
            + ++PV+ QIE +P   Q+ L+  C    I V AYS
Sbjct: 175 LAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYS 211


>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
           Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
           sp. (strain CC9311)
          Length = 336

 Score =  170 bits (414), Expect = 2e-41
 Identities = 85/209 (40%), Positives = 135/209 (64%), Gaps = 10/209 (4%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L++G+ +P++ LGTG+  +++      V ++V  AI+ GYRHID A++Y +EE+VG  I 
Sbjct: 24  LSNGDRMPLLGLGTGKSESRQ------VYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 451
           +AI N  +TR EL++T+KLW++ H ++ V  AL +SL+ LG+DY++LYLIH+P+  +P  
Sbjct: 78  DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEK 137

Query: 452 ------DD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 607
                 DD  +P+     ETW+ M+  R  GL + IGVSNF   ++ +LVS+   +P +N
Sbjct: 138 TFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVN 197

Query: 608 QIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           Q+E +P   Q  L+ +C S  I + AYSP
Sbjct: 198 QVEHHPLLQQPTLIEYCASEEILITAYSP 226


>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 322

 Score =  170 bits (414), Expect = 2e-41
 Identities = 91/218 (41%), Positives = 136/218 (62%), Gaps = 13/218 (5%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           +  P   L++G  +P++ LGT R         + V QAV  AI+ GYRH D A +Y +E 
Sbjct: 1   MSTPNFLLSNGKNMPMLGLGTWRSPP------EVVTQAVKDAIDIGYRHFDCAHIYGNEA 54

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
           QVG  + E +  G+VTR+ELF+T+KLWN  H  D V PA + S++ LG+ Y++LYL+H+P
Sbjct: 55  QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114

Query: 437 IATK----------PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
           +A K          PD +    ++IDY++TW+ M++    GL ++IGVSNFN  Q+ RL+
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174

Query: 578 SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
           S + ++PV+ QIE +P  +Q+PL+  C    IAV AYS
Sbjct: 175 SVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYS 212


>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
           n=11; Theria|Rep: Aldo-keto reductase family 1 member
           C13 - Mus musculus (Mouse)
          Length = 323

 Score =  170 bits (414), Expect = 2e-41
 Identities = 89/219 (40%), Positives = 135/219 (61%), Gaps = 13/219 (5%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+ +  C++LNDG+ IP  ALG G    KE      + +A   A++ GYRH+DTA  YQ 
Sbjct: 1   MSSKQHCVKLNDGHLIP--ALGFGTYKPKEVPKSKSL-EAACLALDVGYRHVDTAYAYQV 57

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           EE++GQ I   I  G+V RE+LF+TTKLW      + V PAL++SLKKL LDY+DLY++H
Sbjct: 58  EEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMH 117

Query: 431 FPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
           +P+  K  D+            D +D+ +TW+ +++ +  GL +SIGVSNFN  Q+ R++
Sbjct: 118 YPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERIL 177

Query: 578 SNSYI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAY 688
           +   +  +PV NQ+E +    Q  L+ +C+S  I ++AY
Sbjct: 178 NKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAY 216


>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
           Aldo-keto reductase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 324

 Score =  170 bits (413), Expect = 3e-41
 Identities = 93/219 (42%), Positives = 129/219 (58%), Gaps = 15/219 (6%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P ++LN+G  +P + LGT           DE  +AV  AI+ G+RHIDTA  Y++E+ VG
Sbjct: 7   PTVKLNNGLEMPAIGLGTSMSKG------DECCKAVMTAIDEGFRHIDTAYNYRNEDVVG 60

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + I   I  G+VTREELFVTTKLWN  H  D V  A  +SL+ LGLDY+DL+LIH P   
Sbjct: 61  RAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGY 120

Query: 446 K----------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 580
           +          P D   N+     DY++TW+ M+   + G   SIGVSNFN+ Q+ R+++
Sbjct: 121 EFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILA 180

Query: 581 NSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           N  ++PV NQ+E +    Q+ L+  C    I V A+SPF
Sbjct: 181 NCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPF 219


>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
           n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
           protein - Oryza sativa (Rice)
          Length = 337

 Score =  169 bits (412), Expect = 4e-41
 Identities = 96/224 (42%), Positives = 135/224 (60%), Gaps = 14/224 (6%)
 Frame = +2

Query: 65  AAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVY 244
           AA A   PC+ LN G+ +P++  GTG  T        ++   +  A+  GYRH+DTAAVY
Sbjct: 14  AAAATAVPCVTLNSGHAMPVLGFGTGSSTPPA-----DLAATIAHAVRLGYRHLDTAAVY 68

Query: 245 QDEEQVGQGIAEAIANGLV-TREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDL 418
             E  VG  +AEA+  G V +R ELFVTTKL   D H   +VV AL+ESL +LGLDY+DL
Sbjct: 69  GTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHP-PRVVAALRESLSRLGLDYVDL 127

Query: 419 YLIHFPIATKPDDSPDNI------------DYLETWQGMQDARQLGLARSIGVSNFNATQ 562
           +LIH+P+A    D+   +            D    W+GM++  +LGLARSIGVSNF+A +
Sbjct: 128 FLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAK 187

Query: 563 ITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++RL++ + + P +NQ+E+N    QE +   C   G+ V AYSP
Sbjct: 188 MSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSP 231


>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
           Endopterygota|Rep: ENSANGP00000031808 - Anopheles
           gambiae str. PEST
          Length = 316

 Score =  169 bits (412), Expect = 4e-41
 Identities = 95/209 (45%), Positives = 124/209 (59%), Gaps = 12/209 (5%)
 Frame = +2

Query: 104 DGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 283
           +GN+IP+  LGT            +V QAV  AI+ GYRHID A VYQ+E +VG+GIA  
Sbjct: 13  NGNSIPMFGLGTWNSPP------GQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAK 66

Query: 284 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----- 448
           IA G+V RE+LFVT+KLWN  H  D V  A + +L+ L LDY+DLYLIH+P+  +     
Sbjct: 67  IAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTEL 126

Query: 449 ----PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 607
               PD       + DY++TW  M+     GL R+IGVSNFNA Q+ R++  + I P  N
Sbjct: 127 FPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATN 186

Query: 608 QIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           QIE +P   Q  +   C   GI V AYSP
Sbjct: 187 QIECHPYLHQSKITTFCAEKGIIVTAYSP 215


>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
           str. PEST
          Length = 319

 Score =  166 bits (404), Expect = 4e-40
 Identities = 90/224 (40%), Positives = 134/224 (59%), Gaps = 16/224 (7%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+ Q P ++ ++G  IP+  LG G   A++   ++ V++A    I+ GYRHIDTA +Y++
Sbjct: 1   MSTQVPTVRFSNGYEIPV--LGYGTYLAQKGQCVELVKKA----IDLGYRHIDTAFLYEN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E ++GQ I + IA G++ RE++FVTTKLWN  H    V  A + S   L + YIDL+L+H
Sbjct: 55  EVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMH 114

Query: 431 FPIAT----------KPDDSPDN-----IDYLETWQGMQD-ARQLGLARSIGVSNFNATQ 562
            P+            +P D+  N     +DY+ETW+ M+      G  RSIG+SNFN+ Q
Sbjct: 115 SPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQ 174

Query: 563 ITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           I R++  + ++PV NQ+E NP   Q  L+A CQ+ GI V AY P
Sbjct: 175 IERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGP 218


>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
           eudicotyledons|Rep: Chalcone reductase - Sesbania
           rostrata
          Length = 322

 Score =  166 bits (403), Expect = 5e-40
 Identities = 86/214 (40%), Positives = 142/214 (66%), Gaps = 11/214 (5%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYW-AIEAGYRHIDTAAVYQDEEQV 262
           P + LN G+ +P++    G GT+ ES   ++V  +++  AI+ GYRH D+A+VY  EE +
Sbjct: 7   PEVLLNSGHKMPVI----GMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAI 62

Query: 263 GQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
           G  +++AI  GL+ +R+E+F+T+K WN     D +VPAL+ +LKKLG++Y+DLYLIH+P+
Sbjct: 63  GMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPV 122

Query: 440 ATKPD-DSP------DNIDY-LE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
             + D ++P      D + + +E TW+ M++  +LGLA+SIG+ N+   ++T+L+  + I
Sbjct: 123 RLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATI 182

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            P +NQ+E+NP+  Q  L   C+  GI V A+SP
Sbjct: 183 PPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSP 216


>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
           n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
           C18 - Mus musculus (Mouse)
          Length = 323

 Score =  165 bits (402), Expect = 7e-40
 Identities = 85/212 (40%), Positives = 132/212 (62%), Gaps = 13/212 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I+LNDG++IP++  GT    A E     +  ++   AI+ G+ HID + +YQ+EE++GQ 
Sbjct: 8   IELNDGHSIPVLGFGT---YATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQA 64

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I   I +G V RE++F T+KLW+  H  + V P+L+ SL+KL LDY+DLYLIHFP++ KP
Sbjct: 65  ILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP 124

Query: 452 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 592
            +   P         D +D  +TW+ M+  +  GLA+SIGVSNFN  Q+  +++   +  
Sbjct: 125 GNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAY 688
           +PV NQ+E +    Q  L+A+C+   I ++AY
Sbjct: 185 KPVCNQVECHLYLNQSKLLAYCKMNDIVLVAY 216


>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
           GCY protein - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 295

 Score =  165 bits (401), Expect = 9e-40
 Identities = 92/217 (42%), Positives = 140/217 (64%), Gaps = 5/217 (2%)
 Frame = +2

Query: 59  LNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA 238
           +++ +++      LN+G  IP + LGT       +D  D   +A   A++ GY+HIDTAA
Sbjct: 1   MSSQLSINTKTYTLNNGLKIPAIGLGTWL-----ADEEDAAYKATLTALKNGYKHIDTAA 55

Query: 239 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 418
            Y +E+QVG+    AIA+  V+R+E+FVTTKLWND+H   +   AL ESLKKLGL+Y+DL
Sbjct: 56  AYGNEDQVGR----AIADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDL 109

Query: 419 YLIHFPIATKP-DDSP-DNIDYLETWQGMQDARQLG-LARSIGVSNFNATQITRLVSNSY 589
           YLIH+P++  P  + P D+ D+++TW+ +Q   + G   ++IGVSNFN  ++ +L+++  
Sbjct: 110 YLIHWPLSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEG 169

Query: 590 IR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +   PVINQIE +P  TQ  L  + +S  I + AYSP
Sbjct: 170 VNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSP 206


>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
           division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
           candidate division TM7 genomosp. GTL1
          Length = 299

 Score =  165 bits (400), Expect = 1e-39
 Identities = 90/214 (42%), Positives = 132/214 (61%), Gaps = 12/214 (5%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGR-GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 268
           + L +  T+P++  GT    T   +D ++        AI+AGYRHID A +Y +E++VG+
Sbjct: 4   LTLRNKQTLPLLGYGTWELPTGTTADLVET-------AIKAGYRHIDCAMIYGNEKEVGE 56

Query: 269 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 448
           GI   I  G+V RE+LFVT+KLWN  HA+  V  A +++L  LGLDY+DLYLIH+ +A +
Sbjct: 57  GIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFE 116

Query: 449 PDDSPDNID-----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 595
             D+ + +D             ETWQ M++  + GL +S+GV+NF A  +  L+S + I+
Sbjct: 117 HGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIK 176

Query: 596 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           P ++QIE++P   Q  LVA C S  IAV AYSPF
Sbjct: 177 PAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPF 210


>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
           Aldehyde reductase - gamma proteobacterium HTCC2207
          Length = 330

 Score =  164 bits (399), Expect = 2e-39
 Identities = 96/227 (42%), Positives = 133/227 (58%), Gaps = 20/227 (8%)
 Frame = +2

Query: 74  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 253
           A+Q P ++++   ++P V LG  + T       D   QAVY AI+ GYRH+D+AA Y +E
Sbjct: 4   AIQVPGVKVSS-KSMPAVGLGLWKITQ------DSAAQAVYEAIKVGYRHLDSAADYGNE 56

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
           +QVG+GIA AIA GL +REEL++TTKLWN  H  + V  A + S+  LGLDYIDLYL+HF
Sbjct: 57  QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116

Query: 434 PIATK--------------------PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 553
           PIA +                    P    D +   ETW  M+   + GL R IGV N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176

Query: 554 ATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           A  +  L+S + I+P + QIE +P  TQE L+   +S  +AV A+SP
Sbjct: 177 AVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSP 223


>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
           Aldose reductase - Mus musculus (Mouse)
          Length = 316

 Score =  164 bits (399), Expect = 2e-39
 Identities = 89/214 (41%), Positives = 129/214 (60%), Gaps = 13/214 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++LN+G  +P + LGT +          +V +AV  AI+ GYRHID A VYQ+E++VG  
Sbjct: 5   LELNNGTKMPTLGLGTWKSPP------GQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVA 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + E +   +V R++LF+ +KLW   H +  V  A Q++L  L LDY+DLYLIH+P   KP
Sbjct: 59  LQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKP 118

Query: 452 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 592
                  D S    P + D+++TW  M+     GL ++IGVSNFN  QI R+++   +  
Sbjct: 119 GPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKY 178

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +P +NQIE +P  TQE L+ +C S GI V AYSP
Sbjct: 179 KPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSP 212


>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
           Aldose reductase - Homo sapiens (Human)
          Length = 316

 Score =  164 bits (399), Expect = 2e-39
 Identities = 91/212 (42%), Positives = 128/212 (60%), Gaps = 13/212 (6%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  +PI+ LGT +          +V +AV  AI+ GYRHID A VYQ+E +VG  I 
Sbjct: 7   LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 451
           E +   +V REELF+ +KLW   H +  V  A Q++L  L LDY+DLYLIH+P   KP  
Sbjct: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120

Query: 452 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 598
                D+S    P + + L+TW  M++    GL ++IG+SNFN  Q+  +++   +  +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +NQIE +P  TQE L+ +CQS GI V AYSP
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSP 212


>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
           Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
           atlanticus HTCC2559
          Length = 316

 Score =  163 bits (395), Expect = 5e-39
 Identities = 86/212 (40%), Positives = 135/212 (63%), Gaps = 11/212 (5%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++  DG++IP + LGT +     SD  ++V++AV  A+E GY+HID AA Y +E+ VG+ 
Sbjct: 4   LKFRDGDSIPSIGLGTWK-----SDP-EDVKKAVKIALENGYKHIDCAAAYDNEDAVGEA 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
             E+  +G V RE++FVT+KLWN+ H ++ V+PAL+++LK L LDY+DLYL+H+P+A KP
Sbjct: 58  FKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKP 117

Query: 452 --DDSPD-NIDYL--------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
             +  P+ + DYL        ET   M +A++ GL + +GVSNF+  ++  L       P
Sbjct: 118 SVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMP 177

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +NQ+E++P   Q  L ++C   GI +  YSP
Sbjct: 178 EMNQVELHPYLPQNDLYSYCSKEGILLTGYSP 209


>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
           Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
           sativa (Rice)
          Length = 323

 Score =  161 bits (392), Expect = 1e-38
 Identities = 86/212 (40%), Positives = 129/212 (60%), Gaps = 9/212 (4%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + L  G   P+ A+G G   +  + S +  R A   A+E G+RH DTAA+Y  E  +G
Sbjct: 5   PEVALRHGAGRPMPAVGVGTADSAAT-SPETKRGAALAALEVGFRHFDTAALYGTEAPLG 63

Query: 266 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           + IAEA   GLV +REE+FVTTKLW  +     V+P+L+ESL+ L ++Y+DLYL+H+PI+
Sbjct: 64  EAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPIS 123

Query: 443 TKPD--------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
            KP         +     D+   W+ M++  +LGLA++IGVSNF    + +L++ + I P
Sbjct: 124 VKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVATIPP 183

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +NQ+E+NP   Q  +  +C + GI V AYSP
Sbjct: 184 AVNQVEMNPVWQQRTVREYCAAKGIRVAAYSP 215


>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
           Oryza sativa (japonica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. japonica
           (Rice)
          Length = 288

 Score =  161 bits (392), Expect = 1e-38
 Identities = 85/214 (39%), Positives = 131/214 (61%), Gaps = 11/214 (5%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P   L+ G  +P V +GT       +D    V+  V  AIEAGYRH DTAAVYQ E  +G
Sbjct: 2   PEAALSSGKPMPRVGMGTASFPLGATDP-STVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60

Query: 266 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
             +AEA+  GLV +R+EL++T+KLW        V+P+L+ +L+K+ ++Y+DLYLIHFP++
Sbjct: 61  DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120

Query: 443 TKPDDSPDNIDYLE----------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
            +  + P+++ Y +           W+ M++ ++LGL ++IGVSNF+  ++  L+S + I
Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATI 180

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            P  NQ+EV+P   Q  L   C+  GI + AYSP
Sbjct: 181 SPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSP 214


>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
           1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
           oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
          Length = 321

 Score =  161 bits (392), Expect = 1e-38
 Identities = 87/205 (42%), Positives = 131/205 (63%), Gaps = 11/205 (5%)
 Frame = +2

Query: 113 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 292
           T+P V +GT    A    S ++   A+  AIE GYRH DTA +Y  E  VG+ +AEA+  
Sbjct: 15  TMPRVGMGTA---AFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRR 71

Query: 293 GLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--DS 460
           GL+ +R ++FVT+K+W +D HA  +VVPA +E+L+ LG+DY+DL L+H+P++  P   D 
Sbjct: 72  GLIASRADVFVTSKIWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDF 130

Query: 461 P-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
           P        + D    W+GM++  +LGLAR+IGVSNF+A ++ +L+S + +RP +NQ+EV
Sbjct: 131 PFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEV 190

Query: 620 NPTNTQEPLVAHCQSLGIAVMAYSP 694
           NP   Q  L   C+  G+ +  YSP
Sbjct: 191 NPMWQQRTLREVCRREGVQLCGYSP 215


>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 293

 Score =  161 bits (391), Expect = 1e-38
 Identities = 84/203 (41%), Positives = 130/203 (64%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + +N+G+ IP + LG       + D+ ++ + A+ WA+ AGYRHIDTAA Y +E+ VG
Sbjct: 12  PDLPMNNGHQIPQLGLGVF-----QVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVG 66

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + I E+     V R+++FVT+KLWN     D+   A QE+L KLGLDY+DLYLIH+P   
Sbjct: 67  EAIRESD----VPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP--- 119

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
               +P    YL++W+ M+D  + G  ++IGVSNFN TQ+  ++++  ++PV++QIE +P
Sbjct: 120 ----AP---GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHP 172

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  + A+ +S GI   A+SP
Sbjct: 173 YFQQNDMHAYLESQGILHEAWSP 195


>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
           tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 345

 Score =  159 bits (386), Expect = 6e-38
 Identities = 93/234 (39%), Positives = 130/234 (55%), Gaps = 31/234 (13%)
 Frame = +2

Query: 80  QAPCIQLNDGNTIPIVALGT------------------GRGTAKESDSIDEVRQAVYWAI 205
           Q   IQL+DG  +P+VA GT                  G     E   ID+VR A   A+
Sbjct: 5   QGASIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMAL 64

Query: 206 EAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQES 385
           + GYRH+D A +Y  E  VGQ   E  A+G + RE+LF T+KLWN  H    V PAL+++
Sbjct: 65  DLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKT 124

Query: 386 LKKLGLDYIDLYLIHFPIATKPDDS--P---------DNIDYLETWQGMQDARQLGLARS 532
           L  L +DY+DLYLIH P++ KP +   P         D  D L+TWQ +++ R  GL +S
Sbjct: 125 LSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKS 184

Query: 533 IGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAY 688
           IGVSNFN  Q+  +++   +  +PV NQIE +P   Q+ ++  C+S  I V+AY
Sbjct: 185 IGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAY 238


>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
           synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
           6'-deoxychalcone synthase - Glycine max (Soybean)
          Length = 315

 Score =  159 bits (386), Expect = 6e-38
 Identities = 83/217 (38%), Positives = 137/217 (63%), Gaps = 8/217 (3%)
 Frame = +2

Query: 68  AMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQ 247
           A A++ P I   + +    + +  G G+A +     + ++A+  A++ GYRH DTAA Y 
Sbjct: 2   AAAIEIPTIVFPNSSAQQRMPV-VGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYG 60

Query: 248 DEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 427
            E+ +G+ + EAI  GLV+R++LFVT+KLW  ++    V+PAL++SLK L L+Y+DLYLI
Sbjct: 61  SEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLI 120

Query: 428 HFPIATKPD--DSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 583
           H+P++++P     P  +      D    W+ M++ ++LGL ++IGVSNF+  ++  L+S 
Sbjct: 121 HWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSV 180

Query: 584 SYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           + IRPV++Q+E+N    Q+ L   C+  GI V A+SP
Sbjct: 181 ATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSP 217


>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
           Aldehyde reductase - Salinibacter ruber (strain DSM
           13855)
          Length = 321

 Score =  159 bits (385), Expect = 8e-38
 Identities = 81/211 (38%), Positives = 130/211 (61%), Gaps = 10/211 (4%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I   +G+ +P++ LGT +          EV +AV  A+EAGYRH+D A +Y++E +VG  
Sbjct: 4   ISFENGDEMPMIGLGTWKSPP------GEVYEAVTTALEAGYRHVDCAPIYKNETEVGAA 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 448
           ++++   G + R++++VT+KLWN+ H  D V PAL+++L  L LD +DLYLIH+P+A + 
Sbjct: 58  LSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQP 117

Query: 449 -------PDD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 601
                  PDD  SP+ +   ETW  M+  ++ GL R IGVSNF+   +  ++    +RP 
Sbjct: 118 EVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPE 177

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +NQ+E++P   Q  LV+  ++  I + AYSP
Sbjct: 178 MNQVEMHPYLPQPELVSFAEAHNIPITAYSP 208


>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
           1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
           n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
           4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
           5-beta-reductase) - Homo sapiens (Human)
          Length = 326

 Score =  159 bits (385), Expect = 8e-38
 Identities = 88/214 (41%), Positives = 125/214 (58%), Gaps = 13/214 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I L+DGN+IPI+ LGT   +  +S        +V  AI+ GYRHID A +YQ+E +VG+ 
Sbjct: 10  IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I E IA G V RE++F   KLW   H  + V P L+ +L+ L LDY+DLY+I  P+A KP
Sbjct: 68  IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127

Query: 452 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 592
            D      +N  +L        TW+ M+  +  GL +S+GVSNFN  Q+  +++   +  
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +PV NQ+E +P  TQ  L+  CQ   I + AYSP
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSP 221


>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 323

 Score =  158 bits (383), Expect = 1e-37
 Identities = 93/210 (44%), Positives = 126/210 (60%), Gaps = 11/210 (5%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           +N G  IP V  GT +  AK      EV  AV  A+  GYRHID AA+Y++E +VG GI 
Sbjct: 9   INTGAKIPAVGFGTWQ--AKPL----EVENAVEVALREGYRHIDCAAIYRNETEVGNGIR 62

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
           ++   G V REE+F+T KLWN KHA + V PAL ++L+ LG+ Y+DLYL+H+P A K  D
Sbjct: 63  KS---G-VPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGD 118

Query: 458 -----SPD------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI 604
                + D      NIDY+ T++ M+     G  R+IGVSNFN  ++  L+    + P +
Sbjct: 119 KWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAV 178

Query: 605 NQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           NQIE +P   Q  L+  CQS GI + AYSP
Sbjct: 179 NQIEAHPYLQQPDLLQFCQSKGILIEAYSP 208


>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
           Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
           (Mouse)
          Length = 316

 Score =  157 bits (381), Expect = 2e-37
 Identities = 91/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           A  + L  G  +PIV LGT +    +      VR+AV  AI+AGYRHID A VYQ+E +V
Sbjct: 2   AAFVTLLTGAKMPIVGLGTWKSPPAK------VREAVKVAIDAGYRHIDCAYVYQNESEV 55

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           G+ I E I    V RE+LF+ +KLW+    +  V  A Q +L  L LDY+DLYLIH+P  
Sbjct: 56  GEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQG 115

Query: 443 TK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
            +      P D   +I      +L+ W+ M++    GL +++GVSNFN  QI RL++   
Sbjct: 116 FQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPG 175

Query: 590 I--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +  +PV NQ+E +P  TQE L  +C S GI + AYSP
Sbjct: 176 LKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSP 212


>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 286

 Score =  157 bits (381), Expect = 2e-37
 Identities = 89/199 (44%), Positives = 122/199 (61%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IPIV  GT + T     + D V  A    ++AGYRHIDTAA Y +EE VG+   
Sbjct: 13  LNNGTKIPIVGFGTWQ-TPDGQVAYDSVLAA----LKAGYRHIDTAAAYGNEESVGK--- 64

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
            AIA+  V RE+LFVTTKLWN  H  D    AL  SL KLGLDY+DLYLIH+P      D
Sbjct: 65  -AIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRD 123

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 637
           + + ++  +TW+ M++A     AR+IGVSNF    +  L+  + + P +NQI +NP++ +
Sbjct: 124 NWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIFLNPSDME 182

Query: 638 EPLVAHCQSLGIAVMAYSP 694
           + +VA+ +   I   AYSP
Sbjct: 183 DEVVAYNRKHDILSEAYSP 201


>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
           eudicotyledons|Rep: Aldose reductase-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 316

 Score =  156 bits (378), Expect = 6e-37
 Identities = 84/209 (40%), Positives = 123/209 (58%), Gaps = 9/209 (4%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L  G TIP++ +GT         +I  V QA    I+ GYRH DTA +Y  EE +G  +
Sbjct: 7   RLRCGETIPLLGMGTYCPQKDRESTISAVHQA----IKIGYRHFDTAKIYGSEEALGTAL 62

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 451
            +AI+ G V R++LFVT+KLW+  H     + AL ++LK +GLDY+D YL+H+PI  KP 
Sbjct: 63  GQAISYGTVQRDDLFVTSKLWSSDH--HDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG 120

Query: 452 --------DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 607
                   D+   ++   ETWQGM+   ++GL RSIGVSNF++ +I  L+  + + P +N
Sbjct: 121 VSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180

Query: 608 QIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           Q+E++P   Q  L   C+   I V  YSP
Sbjct: 181 QVEMHPLWRQRKLRKVCEENNIHVSGYSP 209


>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 322

 Score =  156 bits (378), Expect = 6e-37
 Identities = 86/218 (39%), Positives = 130/218 (59%)
 Frame = +2

Query: 41  ITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYR 220
           +T + +++  ++ Q   I+LN+G  IP VALG  +     +D   E   A  WA +AGYR
Sbjct: 4   VTASGIISGNISTQR--IKLNNGQEIPQVALGVYKAP---NDGSTE--NACKWAFDAGYR 56

Query: 221 HIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLG 400
           HID+AA Y +EE VG+ +AE      V R E+F+T+KLW+  H  D+   A+++SLKKL 
Sbjct: 57  HIDSAARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLN 114

Query: 401 LDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 580
           +DY+D+YL+H P     +        LE W+ +++A   G  ++IGVSNF+  ++  L++
Sbjct: 115 VDYMDMYLMHSPGTMGAEKR------LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLA 168

Query: 581 NSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           N  I+P +NQIE +P    E L   C S GI + AYSP
Sbjct: 169 NCRIKPAVNQIESHPFFAHEELREACISRGIHIQAYSP 206


>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
           2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
           oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
          Length = 322

 Score =  155 bits (377), Expect = 7e-37
 Identities = 85/205 (41%), Positives = 126/205 (61%), Gaps = 11/205 (5%)
 Frame = +2

Query: 113 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 292
           T+P + +GT    A    S +E   A+  AIE GYRH DTA +Y  E  V + +AEA+  
Sbjct: 17  TMPRIGMGTA---AFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRR 73

Query: 293 GLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP----- 451
           GLV +R ++FVT+KLW +D HA  +VVPA +E+L+ LG+DY+DL L+H+P    P     
Sbjct: 74  GLVASRADVFVTSKLWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDF 132

Query: 452 ----DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
               ++     D    W+GM++  +LGLAR+IGVSNF+A ++ +L+S + +RP  NQ+E+
Sbjct: 133 PFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEM 192

Query: 620 NPTNTQEPLVAHCQSLGIAVMAYSP 694
           NP   Q  L   C+  G+ +  YSP
Sbjct: 193 NPMWQQRTLREVCRREGVQLCGYSP 217


>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
           n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
           dehydrogenase - Xenopus tropicalis (Western clawed frog)
           (Silurana tropicalis)
          Length = 324

 Score =  155 bits (375), Expect = 1e-36
 Identities = 86/213 (40%), Positives = 127/213 (59%), Gaps = 13/213 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++LNDG+ +P++  GT     K   S+ E    V  AI+ GYRHID A +Y +EE+VG+ 
Sbjct: 9   VELNDGHKMPVIGFGT-YAPPKFPKSLAEEGTKV--AIDVGYRHIDCAFLYGNEEEVGRA 65

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I   IA+G V RE++F T KLW+  H  ++V PAL++SLK L LDY+DL++IH P+  KP
Sbjct: 66  IRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKP 125

Query: 452 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 592
            D   P          N D  +TW+ ++  +  GL RSIGVSNFN  Q+  +++   +  
Sbjct: 126 GDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKY 185

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
           +PV NQ+E +    Q  L+  C+S  I ++ YS
Sbjct: 186 KPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYS 218


>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 303

 Score =  154 bits (374), Expect = 2e-36
 Identities = 85/209 (40%), Positives = 127/209 (60%), Gaps = 8/209 (3%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN+G++IP + LGT + T   SD +  ++ AV    E GYR IDTA VY +E+ VGQ 
Sbjct: 2   LALNNGHSIPPIGLGTYKITG--SDGVAAIKSAV----EFGYRLIDTAFVYNNEQVVGQA 55

Query: 272 IAEAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 448
           + E  + G  + RE++F+ +KL    H  + V    + SL++LGLDY+DLYL+H P+A +
Sbjct: 56  LREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAAR 115

Query: 449 PD-------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 607
                    +  D +  LETW+ +++ ++ GL RSIGVSNFN  Q+  +V++  IRPV+N
Sbjct: 116 DSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVN 175

Query: 608 QIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           Q+E +    Q  L   C   GI +MAYSP
Sbjct: 176 QVECSIGFHQVKLRKFCNREGILIMAYSP 204


>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 321

 Score =  154 bits (373), Expect = 2e-36
 Identities = 87/216 (40%), Positives = 127/216 (58%), Gaps = 16/216 (7%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LNDGN IP + LGT       S++  EV  A+  A++ GYRHID AA Y +E+ +G  +
Sbjct: 18  KLNDGNQIPSIGLGT-----YYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSL 72

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 445
            E    G + RE++F T+KLWN  H  + VV    ++++ LG+ Y+DLYLIH+PIA   +
Sbjct: 73  KEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENS 132

Query: 446 KP--------DDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 586
            P         D   N     +   ETWQ M+   +LGL +SIGVSNFN   +  L++ +
Sbjct: 133 NPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYA 192

Query: 587 YIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            I+PV+NQ+E++P  TQ  L  +C    I ++AYSP
Sbjct: 193 KIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSP 228


>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
           Corynebacterium|Rep: Putative oxidoreductase -
           Corynebacterium diphtheriae
          Length = 290

 Score =  153 bits (372), Expect = 3e-36
 Identities = 82/203 (40%), Positives = 123/203 (60%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I LNDG  +P +  GT +   +E D+   VR A    IE GYRHIDTA++Y++EE+VG
Sbjct: 12  PTITLNDGTEMPAIGFGTYK--LREQDAYRAVRSA----IEVGYRHIDTASLYKNEEEVG 65

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + +A+AI  G V R+ELF+TTK+WND H       + QESL +LGLDYID  ++H+P   
Sbjct: 66  RAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP--- 122

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    Y+E++  +   + LG  +S+ V+NF    +  +V+ + I PV+NQ+E++P
Sbjct: 123 ----WPQKGLYVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHP 178

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
             +Q    A  + LG+   A+SP
Sbjct: 179 GFSQAEQRAVDRELGVVTEAWSP 201


>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
           discoideum|Rep: Aldehyde reductase - Dictyostelium
           discoideum AX4
          Length = 297

 Score =  153 bits (372), Expect = 3e-36
 Identities = 84/212 (39%), Positives = 127/212 (59%), Gaps = 9/212 (4%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P  +L+ G+ IP+V    G GT K   ++  V +AV  A++AGYRHID AAVY +E++VG
Sbjct: 3   PSFKLSSGHKIPLV----GFGTWKAETTL--VGKAVEVALDAGYRHIDCAAVYLNEKEVG 56

Query: 266 QGIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           +   +       V RE++F+T+KLWN  H ++ V PAL+ +L  LGL Y+DLYL+H+P+A
Sbjct: 57  EAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVA 116

Query: 443 ---TKPD-----DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
              T  D      + + +   ETW+ M+     GL +SIG+SNFN   +  ++S + I+P
Sbjct: 117 FEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKP 176

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
             NQ+E++P  +Q  L   C    I + AYSP
Sbjct: 177 AANQVELHPFLSQPELKKFCDKHNIHLTAYSP 208


>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
           family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 305

 Score =  153 bits (371), Expect = 4e-36
 Identities = 90/203 (44%), Positives = 120/203 (59%), Gaps = 4/203 (1%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IP + LGT            EV +AV  AI+ GYRHID A  Y +E++VG GI 
Sbjct: 7   LNNGYKIPKLGLGTWMSAN------GEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIK 60

Query: 278 EAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 451
            AIA G V REELFVTTKLW+ DKH  D V PA  ESLKKL L+Y+DLY+IH P+     
Sbjct: 61  SAIAKGYVKREELFVTTKLWSTDKHKED-VRPACLESLKKLQLEYLDLYIIHIPLTADKK 119

Query: 452 --DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
             + + + I   ETW+ M+   + GL +SIGVSNFN  ++  L++ + I+P +NQ E + 
Sbjct: 120 TGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHI 179

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              +  L   C+   I +  Y P
Sbjct: 180 YYQRPKLHQFCKKHNIHITGYCP 202


>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
           Aldehyde reductase - Leptospira interrogans
          Length = 278

 Score =  153 bits (371), Expect = 4e-36
 Identities = 84/201 (41%), Positives = 123/201 (61%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I LN+G ++PI+ LG  +     + S  E ++AV  A+EAGYRHIDTA +Y +E  VGQ 
Sbjct: 12  IMLNNGISMPILGLGVWK-----TKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQA 66

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I E+   G + R+E+F+TTKLWN     D+   AL+ SL +LG+D++DLYLIHFP+ +K 
Sbjct: 67  IRES---G-IPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR 122

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
            DS         W+ ++      L ++IGVSN+    +T L+ NS I P +NQ+E +P  
Sbjct: 123 MDS---------WKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFL 173

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  L+ +C+   I + AYSP
Sbjct: 174 NQIHLLEYCKKHKIQLEAYSP 194


>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
           cellular organisms|Rep: Prostaglandin f synthase,
           putative - Leishmania major
          Length = 279

 Score =  153 bits (371), Expect = 4e-36
 Identities = 82/208 (39%), Positives = 127/208 (61%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MAV+   + L++G  +P   LG G   AK+ + +  ++    WA+ AGYRH+DTA  Y++
Sbjct: 1   MAVKCTHVTLSNGVQVP--QLGIGTWEAKDGNEVVNIK----WAVNAGYRHVDTAHYYKN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E+ VGQGI+E    G V R ++FVTTKLWN  H  +  + A ++S + LG++Y+DLYLIH
Sbjct: 55  EKGVGQGISEC---G-VPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIH 110

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
           +P        P N  Y+ETW+  +   ++   R+IGVSNF    +  L++N  + P++NQ
Sbjct: 111 WP-------GP-NRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQ 162

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +E++P   Q+ L A+C    IAV A+ P
Sbjct: 163 VEMHPHFQQKALRAYCAEKNIAVTAWRP 190


>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
           Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
          Length = 312

 Score =  153 bits (371), Expect = 4e-36
 Identities = 92/222 (41%), Positives = 138/222 (62%), Gaps = 21/222 (9%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN G  IP + LGT +  +KE+D+     +AV  A++ GYRHIDTAA+Y++E+QVGQ 
Sbjct: 12  LSLNTGAQIPQIGLGTWQ--SKENDAY----KAVLTALKDGYRHIDTAAIYRNEDQVGQ- 64

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 436
              AI +  V REE+FVTTKLW  +H   +V  AL +SLK+LGLDY+DLYL+H+P     
Sbjct: 65  ---AIKDSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDP 119

Query: 437 ----------IATKPDDSP----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 574
                     + TK D S      N ++++TW+ MQ+  + G  +++GVSNF+   +  L
Sbjct: 120 AYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDL 179

Query: 575 VSN--SYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +++  + + P  NQ+E++P   Q+ L+  C+S GI V AYSP
Sbjct: 180 LASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSP 221


>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
           Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  152 bits (368), Expect = 9e-36
 Identities = 74/177 (41%), Positives = 108/177 (61%), Gaps = 11/177 (6%)
 Frame = +2

Query: 200 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 379
           AI AGYRHIDTA  Y++E  VG  I   I  G++ R+++F+ +KLW   HA + +     
Sbjct: 9   AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68

Query: 380 ESLKKLGLDYIDLYLIHFPIATK-------PDDS----PDNIDYLETWQGMQDARQLGLA 526
           +SL  L LDY+D YL+HFP+  K       P+        +IDY++ W+GM+  +  G  
Sbjct: 69  KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128

Query: 527 RSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           +SIGVSNF   QI RL+S + I P +NQ+E++P   Q  L+ +C+S  IA+ A+SPF
Sbjct: 129 KSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPF 185


>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
           Lactobacillus reuteri 100-23
          Length = 288

 Score =  152 bits (368), Expect = 9e-36
 Identities = 90/200 (45%), Positives = 119/200 (59%), Gaps = 1/200 (0%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IP V  GT R  A      D   QAV  AIE GYRHIDTAAVY +EE VG+GI 
Sbjct: 13  LNNGVKIPCVGYGTFRTPA------DVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGIK 66

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-D 454
           ++   G + RE+LFVT+KLWN     +Q   A QE+L +L +DY+DLYLIH+P   K   
Sbjct: 67  DS---G-IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG 122

Query: 455 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 634
           D    I+  ETW+ M+D    G  R+IGVSNF    I  L+  + + P ++QIEV+P   
Sbjct: 123 DDAAKIN-AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWP 181

Query: 635 QEPLVAHCQSLGIAVMAYSP 694
              +V + Q+  I V A++P
Sbjct: 182 HTEVVKYLQAHNILVEAWAP 201


>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 337

 Score =  152 bits (368), Expect = 9e-36
 Identities = 87/206 (42%), Positives = 118/206 (57%), Gaps = 5/206 (2%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I +ND N + I  +G G   A+ +    EVR AV  A+ AGY H+D AA Y +E +VG+ 
Sbjct: 6   ILVNDANGLRIPRVGLGTWKARPN----EVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + EA   G   RE++FVT+KLWND+     V  AL  +L  LG+ Y+DLYLIH+P+A K 
Sbjct: 62  LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121

Query: 452 DD--SPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN--SYIRPVINQIE 616
                PD      E W  ++     GL R IGVSNFN  Q+  L  +  + I+P  NQIE
Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +P  + + LV + QS G+ V AYSP
Sbjct: 182 SHPLWSNDSLVKYSQSKGLTVTAYSP 207


>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
           organisms|Rep: Probable reductase - Leishmania major
          Length = 284

 Score =  152 bits (368), Expect = 9e-36
 Identities = 83/206 (40%), Positives = 124/206 (60%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           V    + L++G  +P   LG  +  A E         AV WA+ AGYRHIDTAA+Y++EE
Sbjct: 4   VDKAMVTLSNGVKMPQFGLGVWQSPAGEV-----TENAVNWALCAGYRHIDTAAIYKNEE 58

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
            VG G+    A+G V RE++F+TTKLWN +   +  + A +ES +KLG+DYIDLYLIH+P
Sbjct: 59  SVGAGLR---ASG-VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114

Query: 437 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
              K   S +   YL++W+  +   +    R+IGVSNF+   +  +++   + P++NQ+E
Sbjct: 115 -RGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVE 173

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++P N Q  L A C +  I V A+SP
Sbjct: 174 LHPLNNQADLRAFCDAKQIKVEAWSP 199


>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase A - Corynebacterium sp. (strain ATCC 31090)
          Length = 278

 Score =  152 bits (368), Expect = 9e-36
 Identities = 85/203 (41%), Positives = 123/203 (60%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I LNDGN+IP   LG G      +D+    ++AV  A+E GYRHIDTAA+Y +EE VG
Sbjct: 4   PSIVLNDGNSIP--QLGYGVFKVPPADT----QRAVEEALEVGYRHIDTAAIYGNEEGVG 57

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
             IA   A+G + R++LF+TTKLWND+H  D+   A+ ESL KL LD +DLYL+H+P   
Sbjct: 58  AAIA---ASG-IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP--- 110

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
               +P   +Y+  W+ M + R  GL RSIGVSN     + R+V+ + + P +NQIE++P
Sbjct: 111 ----TPAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHP 166

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  +     +  + + ++ P
Sbjct: 167 AYQQREITDWAAAHDVKIESWGP 189


>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 320

 Score =  151 bits (366), Expect = 2e-35
 Identities = 81/208 (38%), Positives = 127/208 (61%), Gaps = 1/208 (0%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+ + P   L++G  +P + LGT + T +E  ++  +R AV     AGYRHIDTA +YQ+
Sbjct: 1   MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTV--IRNAVL----AGYRHIDTATLYQN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E Q+G  +AE  A G++ RE++F+TTK +  + A D V  AL+ SLK+L LDY+DLYL H
Sbjct: 55  EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114

Query: 431 FPIATKPDDS-PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 607
            P +TK D S   ++   + W+G +    LGL ++IGVSNFN +QI R+++   +    +
Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHAS 174

Query: 608 QIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
           Q+E++    Q+     C+   I + AY+
Sbjct: 175 QLELHLYLPQKAHRELCKKHNILITAYA 202


>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
           Aldose reductase - Magnaporthe grisea (Rice blast
           fungus) (Pyricularia grisea)
          Length = 312

 Score =  150 bits (364), Expect = 3e-35
 Identities = 87/213 (40%), Positives = 128/213 (60%), Gaps = 14/213 (6%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN G  IP   LGT +G          +++AV  AI++GYR ID A VY +EE+VGQGI 
Sbjct: 8   LNTGAKIPAFGLGTWQGDK------GVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIR 61

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 451
           EAI++G+V RE+LFV +K W     R ++   L +SLK LGLDY+DLYL+H+PI   P  
Sbjct: 62  EAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMNPEG 119

Query: 452 ---------DDSPDNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 595
                    D S D I   ++++TW+ M+     G  +++GVSN++   + +L+ ++   
Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTV 179

Query: 596 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           P +NQ+E +P   Q+ LV  C+  GI +MAYSP
Sbjct: 180 PAVNQVENHPQLPQQELVDFCKEKGIHIMAYSP 212


>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
           Schizosaccharomyces pombe|Rep: Probable oxidoreductase
           C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
          Length = 321

 Score =  150 bits (364), Expect = 3e-35
 Identities = 86/211 (40%), Positives = 129/211 (61%), Gaps = 11/211 (5%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L DG+ IP + LGT R    ++      + AV  A++ GYRHID AA+Y +E++VG GI 
Sbjct: 18  LADGSKIPGLGLGTWRSEPNQT------KNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK 71

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 448
           E+   G V R++++VT+KLW + HA + V  AL+++LK L LDY+D YLIH+P++ K   
Sbjct: 72  ES---G-VPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGE 127

Query: 449 ---PDDSPDNIDYL-----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI 604
              P D   N+ Y      ETW+ M+   + G  R IG+SNFN T + R++  + ++P +
Sbjct: 128 DKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAV 187

Query: 605 NQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           +Q+E++P   Q   V   + LGI V AYSPF
Sbjct: 188 HQMELHPFLPQTEFVEKHKKLGIHVTAYSPF 218


>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
           Aldehyde reductase 1 - Sporobolomyces salmonicolor
          Length = 323

 Score =  149 bits (362), Expect = 5e-35
 Identities = 86/215 (40%), Positives = 125/215 (58%), Gaps = 16/215 (7%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN G ++ +V  GT +          EV Q V  AIE GYRH+D A VY ++ +VG  I 
Sbjct: 7   LNTGASLELVGYGTWQAAP------GEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK 60

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD- 454
           EA   G V RE+LF+T+KLWN+ H  +QV PAL ++LK+LGL+Y+DLYLIH+P+A  P+ 
Sbjct: 61  EA---G-VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEG 116

Query: 455 DSPDN---------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
           D   N               +  ++TW+ M      G  ++IGVSNF+A  +  ++  + 
Sbjct: 117 DITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATG 176

Query: 590 IRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           + P +NQIE +P   Q  L+AH ++  I + AYSP
Sbjct: 177 VTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSP 211


>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
           Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
           - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
           NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
           DSM 3700 / NRRL 181))
          Length = 321

 Score =  149 bits (361), Expect = 6e-35
 Identities = 90/220 (40%), Positives = 118/220 (53%), Gaps = 16/220 (7%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P  +LN G  +P+V  G  +         D++    Y AI+AGYR  D A  Y +E + G
Sbjct: 4   PSTKLNSGYDMPLVGFGLWK--VNNETCADQI----YHAIKAGYRLFDGACDYGNEVEAG 57

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           +G+A AI  G+V RE+LF+ +KLWN  H  D+V P  ++ L   GLDY DL+++HFPIA 
Sbjct: 58  KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117

Query: 446 KPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
           K  D                   N    ETW  M+      LARSIGVSNF+A  +  L+
Sbjct: 118 KYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLL 177

Query: 578 SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
             + IRP   QIE +P  TQE LV + Q  GIAV AYS F
Sbjct: 178 RYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSF 217


>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
           dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
           D-sorbitol-6-phosphate dehydrogenase - Malus domestica
           (Apple) (Malus sylvestris)
          Length = 310

 Score =  149 bits (361), Expect = 6e-35
 Identities = 82/216 (37%), Positives = 121/216 (56%), Gaps = 15/216 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + L+ G  +P++ LG  R         DE+++ +  AI+ GYRH D AA Y+ E  VG+ 
Sbjct: 4   VTLSSGYEMPVIGLGLWRLEK------DELKEVILNAIKIGYRHFDCAAHYKSEADVGEA 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           +AEA   GLV REELF+TTK+WN  H    VV A + SL+KL +DY+DLYL+H+P+ TK 
Sbjct: 58  LAEAFKTGLVKREELFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLVHYPMPTKH 115

Query: 452 D---------------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 586
           +               D    I   +TW+GM+    LGL RSIG+SN+        ++ S
Sbjct: 116 NAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYS 175

Query: 587 YIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            I+P ++Q E +P   ++ LV  C   G+   A++P
Sbjct: 176 KIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTP 211


>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Exiguobacterium sibiricum 255-15
          Length = 274

 Score =  148 bits (358), Expect = 1e-34
 Identities = 79/201 (39%), Positives = 125/201 (62%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN+G  +P +    G G  K  +   EV +AV  A+  GYR IDTA +Y++E  VG+ 
Sbjct: 4   VTLNNGLVMPQL----GYGVFKVPEQ--EVYEAVREALRVGYRSIDTAMIYENEAGVGR- 56

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
              A+ +  + RE++F+TTK+WN     ++ + A + SL+KLG+DY+DLYLIH+P+    
Sbjct: 57  ---ALKDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---- 109

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
              PD   Y++TW+ ++   + G A++IGVSNF+   +TR++    + P +NQIE++P  
Sbjct: 110 ---PDEDLYMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFL 166

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
           +QE + A CQ  GI V A+SP
Sbjct: 167 SQEAIRAFCQKNGIVVEAWSP 187


>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 333

 Score =  147 bits (357), Expect = 2e-34
 Identities = 79/214 (36%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + L  G+ +P+V LGT +  A      DEV  A+  A++AGYRH D A +Y +E++VG  
Sbjct: 5   VTLPSGHAMPLVGLGTWKLKA------DEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVA 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 442
           + EA+    + RE++F+TTK+WN  HA++ V      SL  L LDYIDLY++H+P+    
Sbjct: 59  LREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQN 118

Query: 443 ---------TKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
                    T+  D    ++ YLETW  M+D  + G  +S+G+SNFN+ Q+  ++ +S +
Sbjct: 119 LGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTV 178

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            P + Q+E +P   Q  L+  C+   + V AYSP
Sbjct: 179 PPSVLQVESHPFLPQVELLNFCRERSVVVSAYSP 212


>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Photorhabdus luminescens subsp. laumondii
          Length = 292

 Score =  147 bits (357), Expect = 2e-34
 Identities = 85/203 (41%), Positives = 123/203 (60%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I+L DGN +P + LG+       SD   ++ + ++ A++ GYR IDTAA+Y +E+ VG
Sbjct: 5   PIIRLADGNHMPQLGLGSWA-----SDD-QQIAETIHAALDIGYRAIDTAAIYNNEKGVG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
             + E      + RE++FVTTKLWND+H   +   AL ESL+KL LDY+DLYLIH+P   
Sbjct: 59  NALQETD----IPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWP--- 109

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
               +P    Y+  WQ + + ++ GL RSIGVSNF    I RL++ + + PVINQIE++P
Sbjct: 110 ----APPQDQYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHP 165

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  L A   +  I   ++SP
Sbjct: 166 LLQQRQLHAWNATHNIVTESWSP 188


>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
           Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
           - Mycobacterium sp. (strain KMS)
          Length = 283

 Score =  147 bits (357), Expect = 2e-34
 Identities = 86/207 (41%), Positives = 123/207 (59%)
 Frame = +2

Query: 74  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 253
           A   P + LNDG++IP++ LG G  +  E++      ++V  A+EAGYR IDTAAVY +E
Sbjct: 8   AAGIPSVSLNDGHSIPVLGLGVGELSEAEAE------RSVAAALEAGYRLIDTAAVYGNE 61

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
             VG+ +    A+G + REE++VTTKL            A + SL++LGLDY+DLYLIH+
Sbjct: 62  AAVGRAVN---ASG-IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW 117

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
           P         D+  Y+++W G+  A+Q G+ARSIGV NFNA  ++ ++  S+  P INQI
Sbjct: 118 PAG-------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           E++P   Q  L       GI   AY P
Sbjct: 171 ELHPLLNQAELREVNAGYGIVTEAYGP 197


>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 316

 Score =  147 bits (357), Expect = 2e-34
 Identities = 82/212 (38%), Positives = 122/212 (57%), Gaps = 11/212 (5%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++LN G +IP + LGT +          EV  A+  A+ AGYRHID A VYQ++++VG+ 
Sbjct: 5   LKLNSGYSIPAIGLGTWQSKP------GEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEA 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IAT 445
           + E +  G V REELF+T+K+WN  H+  +    +   L  L L Y+DL LIH+P   A 
Sbjct: 59  LKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118

Query: 446 KPDDSP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
             +  P          ++DYLETW+  + A++ G  RSIG+SNF  +QI R+   + ++P
Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKP 178

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
              Q+E++P  TQ  L   C+  GI V+ YSP
Sbjct: 179 ACLQVELHPYFTQVKLREFCKEKGIVVVGYSP 210


>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
           700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
          Length = 280

 Score =  147 bits (356), Expect = 3e-34
 Identities = 88/201 (43%), Positives = 119/201 (59%), Gaps = 2/201 (0%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LNDGN IPIV  GT +  A E + I  ++++   A+  GYR IDT A+YQ+EE VG+ I 
Sbjct: 5   LNDGNRIPIVGFGTYK--ANEEEGIKSIQKS---ALTLGYRLIDTVAIYQNEEAVGKAIK 59

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IATKP 451
              A G V REE+FVTTKLW +     Q   AL ESL+KL L+YIDLYLIH+P       
Sbjct: 60  ---ARG-VLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYK 115

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
           D    N D   TW+ M++ +  G  +S+GVSNF    +  L   + + P +NQIE +P  
Sbjct: 116 DWQKTNAD---TWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGY 172

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  +   C++ GIAV ++SP
Sbjct: 173 WQPQVTEFCKNHGIAVESWSP 193


>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=3; Lactobacillales|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Leuconostoc mesenteroides subsp. mesenteroides (strain
           ATCC 8293 /NCDO 523)
          Length = 292

 Score =  147 bits (356), Expect = 3e-34
 Identities = 77/172 (44%), Positives = 106/172 (61%)
 Frame = +2

Query: 182 RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQ 361
           +QAV  AI+ GYR IDTAA Y +E +VG+ I EAI  G+V REELFVT+K+W    +  Q
Sbjct: 29  KQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIVKREELFVTSKMWVQDVSAQQ 88

Query: 362 VVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGV 541
              A+Q SL++L LDY+DLYLIH P            D    W+ M+ A + G  ++IGV
Sbjct: 89  ATAAIQSSLQRLNLDYLDLYLIHQPYN----------DVFGAWRAMESAYRSGQLKAIGV 138

Query: 542 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           SNF+  Q+T L   S I+P++NQIEVNP    +  + +    G+ V A++PF
Sbjct: 139 SNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITYFSQYGVQVEAWAPF 190


>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=2; Tetrahymena thermophila SB210|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 332

 Score =  147 bits (355), Expect = 3e-34
 Identities = 76/201 (37%), Positives = 125/201 (62%), Gaps = 1/201 (0%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN+G  +P+V LGT    +KE     E+   +  A++AGYRHIDTA  YQ+E  +G+ +
Sbjct: 9   KLNNGQIMPLVGLGTYLLNSKE-----EMTNLLRTALDAGYRHIDTAVNYQNEAMIGESL 63

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
                 G  +R++LF+ +K++ +K     ++ ++++SLK+L LDY+DLY +HFP+    +
Sbjct: 64  KTIFKEGKYSRKDLFIVSKVFPNKGIN--MLESVKKSLKELQLDYVDLYYLHFPLGFLSE 121

Query: 455 DSPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                ++     W  +++A +LGLA+SIGVSNFN   +  L+S + ++PV NQ+EV+   
Sbjct: 122 KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFI 181

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q+ L+  CQ  GI V AY+P
Sbjct: 182 QQKNLIKFCQRFGIHVTAYAP 202


>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
           Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
           posadasii
          Length = 314

 Score =  147 bits (355), Expect = 3e-34
 Identities = 85/218 (38%), Positives = 127/218 (58%), Gaps = 11/218 (5%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA +    +LN G  IP +  GT +    + D       AV  A+ AGYRHIDTAAVY  
Sbjct: 1   MASRHTTFRLNTGEDIPAIGFGTWQDENAQED-------AVLTALSAGYRHIDTAAVYGT 53

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E+ +G+    A+A   ++R+ELF+T+KLWN+KH  + V  A+ +SLK L +DY+DLYL+H
Sbjct: 54  EKAIGR----ALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMH 109

Query: 431 FPIATK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
           +P A        P DS  N     IDY++T++ M+   + G  ++IG+SNF+  ++ RL+
Sbjct: 110 WPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLL 169

Query: 578 SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
            +  I P + Q+E++P   Q   V   +S GI V  YS
Sbjct: 170 ESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYS 207


>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
           Dikarya|Rep: Aldo-keto reductase, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 353

 Score =  147 bits (355), Expect = 3e-34
 Identities = 87/231 (37%), Positives = 133/231 (57%), Gaps = 14/231 (6%)
 Frame = +2

Query: 44  TLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRH 223
           T+  + N+ +       +LN G +IP + LGT +  A       EVRQAV  A++AGYRH
Sbjct: 23  TILPIFNSLIMSAPTSFKLNTGASIPAIGLGTWQAKA------GEVRQAVAHALKAGYRH 76

Query: 224 IDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGL 403
           ID A  YQ+E++VG GI ++   G V R E+F+T+K+W+  H  D+V   L  +LK L  
Sbjct: 77  IDGALCYQNEDEVGLGIKDS---G-VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQT 130

Query: 404 DYIDLYLIHFPIATKPDDS-------PD---NIDY----LETWQGMQDARQLGLARSIGV 541
           DY+DLYLIH+P+   P+ +       PD   N+D+     +TW  M+D  + G A++IG+
Sbjct: 131 DYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGL 190

Query: 542 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           SN     I  ++    + P +NQ+E++P   Q  L+ +C+  GI + AYSP
Sbjct: 191 SNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSP 241


>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus acidophilus
          Length = 285

 Score =  146 bits (353), Expect = 6e-34
 Identities = 78/199 (39%), Positives = 119/199 (59%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IPI+  GT      ++   +   ++V  A+  GYRHIDTA+ Y +E+ VG+ I 
Sbjct: 12  LNNGVKIPIIGFGTW-----QTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ 66

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
           ++  N    R ELF+TTKLWN  H  ++   A+ +SL  L LDY+D+YLIH+P  +   D
Sbjct: 67  KSGIN----RHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD 122

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 637
               I+  E+W+ M++A + G  R+IGVSNF    +  L+  + I+PV+NQI +NP++ Q
Sbjct: 123 HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQ 181

Query: 638 EPLVAHCQSLGIAVMAYSP 694
             +V   + L +   AYSP
Sbjct: 182 SEVVTENKKLDLLSEAYSP 200


>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
           melanogaster|Rep: CG40064-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 361

 Score =  146 bits (353), Expect = 6e-34
 Identities = 73/173 (42%), Positives = 108/173 (62%), Gaps = 12/173 (6%)
 Frame = +2

Query: 188 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 367
           AV+ AIE G+RH DTA  Y++E+++G+ +   I  G ++RE +F+TTKLWN  H    V 
Sbjct: 49  AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108

Query: 368 PALQESLKKLGLDYIDLYLIHFPIATK--------PDDSPD----NIDYLETWQGMQDAR 511
              ++ L+ LG  YIDLYL+HFP+  K        P    +     IDYL+TW+ M++  
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168

Query: 512 QLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLG 670
           +LG+ RSIG+SNFN  QI R++  S  +PV+NQ+E+ P   Q+ LV +C+  G
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221


>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score =  146 bits (353), Expect = 6e-34
 Identities = 84/199 (42%), Positives = 116/199 (58%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L+DG  IP   LG      K +      +QAV WA+E GYR IDTAA Y +E++VG    
Sbjct: 9   LSDGYKIPRFGLGLYDLDEKHT------KQAVLWALENGYRMIDTAASYNNEKRVG---- 58

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
           EA+    V R E+++ TK+++  H  ++ + A   SL  LG+DY+DLYLIHFP+      
Sbjct: 59  EALRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV------ 112

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 637
            P  +  + +W+ M + +  GL RSIGVSNFN   +  L  +S I PV+NQIEV+P    
Sbjct: 113 -PAGV--VGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQM 169

Query: 638 EPLVAHCQSLGIAVMAYSP 694
           E LV  C+   IA+ AYSP
Sbjct: 170 EELVDFCRKHSIAIQAYSP 188


>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Yersinia pestis
          Length = 277

 Score =  144 bits (350), Expect = 1e-33
 Identities = 86/203 (42%), Positives = 117/203 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I+L DG  +P + LG  +       SI E   AV  A+E GYR IDTAA+Y++EE VG
Sbjct: 5   PLIKLYDGRLMPQLGLGVWQA------SIQETELAVSKALEVGYRSIDTAAIYKNEEGVG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + +  A     V R+ELF+TTKLWND     Q   AL+ SL+KL LDY+DLYLIH+P   
Sbjct: 59  KALKAAA----VARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP--- 109

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    Y+  W+ +   ++ GL RSIGV NF+   + RL+  + I P +NQIE++P
Sbjct: 110 ----DPKQDHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHP 165

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  L A   +  IA  ++SP
Sbjct: 166 LLQQRQLHAWNATHHIATESWSP 188


>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
           Yarrowia lipolytica chromosome B of strain CLIB122 of
           Yarrowia lipolytica - Yarrowia lipolytica (Candida
           lipolytica)
          Length = 337

 Score =  144 bits (349), Expect = 2e-33
 Identities = 87/215 (40%), Positives = 127/215 (59%), Gaps = 15/215 (6%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAI-EAGYRHIDTAAVYQDEEQVGQGI 274
           LN+G TIP + LGT + T       +EV  AV  A+ E GYRHIDTA  Y++E+ VG GI
Sbjct: 36  LNNGKTIPAIGLGTWKSTT------EEVAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
             A+  G V RE++FVTTK+W   H  D+V   L  SL++LGLDY+D+ LIH+P+   P+
Sbjct: 90  KRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPN 146

Query: 455 DS-------PD---NIDYL----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
            +       PD   +ID      +TW+ M+   + G  +SIGVSNF+   +  L+  + +
Sbjct: 147 GNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEV 206

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
            P +NQ+E++P   Q  L+  C+   I + A+SPF
Sbjct: 207 VPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPF 241


>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
           Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
           putida
          Length = 296

 Score =  144 bits (349), Expect = 2e-33
 Identities = 86/208 (41%), Positives = 128/208 (61%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA ++P I LN+G  +P + LG    +A+E+ S      A+  AI +GYR IDTA  Y +
Sbjct: 1   MAGKSPLINLNNGVKMPALGLGVFAASAEETAS------AIASAISSGYRLIDTARSYNN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E QVG+GI     N  V R E+FVTTKL+N  +  ++ + A  ESL +LGLDY+DLYL+H
Sbjct: 55  EAQVGEGIR----NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLH 110

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
           +P  TK  ++      +++W+  +     G AR+IGV NF   Q+  L++ S + P +NQ
Sbjct: 111 WP--TKDWNAT-----IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IE++P   Q+PL+A  ++LGI   A+SP
Sbjct: 164 IELHPYFAQKPLLAKNRALGIVTEAWSP 191


>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=10; Trichomonas vaginalis|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 312

 Score =  144 bits (348), Expect = 2e-33
 Identities = 80/200 (40%), Positives = 120/200 (60%), Gaps = 16/200 (8%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 316
           G GT   +D   +++ A+++AIE  G RHIDTA  Y ++  +G+ + E  A G + RE++
Sbjct: 7   GFGTYLANDPA-KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKREDM 65

Query: 317 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----------PDDSP- 463
           F+TTKLW   H +D V P L E+L +L L Y+DL+LIH PIA K          P D   
Sbjct: 66  FITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKG 125

Query: 464 ----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
               + ID LET+  M++ ++ GL R IGVSNF+  Q+ R+  N  I+P  NQ+E N   
Sbjct: 126 KIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECNIYR 185

Query: 632 TQEPLVAHCQSLGIAVMAYS 691
             +PL+++C+S  I +MA++
Sbjct: 186 QFKPLLSYCESHNIYLMAHT 205


>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
           Saccharomycetaceae|Rep: Glycerol dehydrogenase -
           Zygosaccharomyces rouxii (Candida mogii)
          Length = 310

 Score =  144 bits (348), Expect = 2e-33
 Identities = 89/221 (40%), Positives = 130/221 (58%), Gaps = 20/221 (9%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++LN G TIP V LGT R  +KE++      +AV  A++AGYRHID AAVY +E +VG+ 
Sbjct: 11  LKLNTGQTIPQVGLGTWR--SKENEGY----KAVIEALKAGYRHIDGAAVYGNEGEVGK- 63

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI---- 439
              AI +  V R E+F+TTKLW       Q   AL +SL++LGLDY+ LYL+H+P+    
Sbjct: 64  ---AIQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRT 118

Query: 440 -----------ATKPDDSPD---NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
                      A KPD S D     ++++TW+ MQ   + G  ++IGVSNF+   +  L+
Sbjct: 119 ENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLL 178

Query: 578 S--NSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +   + + P +NQ+E +P   QE L+ +C   GI + AYSP
Sbjct: 179 AAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSP 219


>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
           protein; n=6; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to LOC553452 protein -
           Strongylocentrotus purpuratus
          Length = 321

 Score =  143 bits (347), Expect = 3e-33
 Identities = 87/222 (39%), Positives = 122/222 (54%), Gaps = 14/222 (6%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA     I L  G  +P++  GT +         +EV + +  AI+ GYRHID A++Y +
Sbjct: 1   MASSNTHIVLPGGRKLPLLGFGTWQIKP------EEVGRVIETAIDCGYRHIDEASLYGN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLI 427
           E+ VG GI   I +G + RE+LFVT+KLW  D H   +V P+ ++SL  LGL Y+DL+LI
Sbjct: 55  EKGVGDGIKAKIDDGTIKREDLFVTSKLWVTDSHP-SRVEPSCRQSLSDLGLAYLDLFLI 113

Query: 428 HFPIATKPDDSP------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 571
           H P +      P            D IDY++TW+ M+     GL R+IGVSNF   QI R
Sbjct: 114 HCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQR 173

Query: 572 LVSNSYIRPVIN-QIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++      P+ N Q+E +P   Q  L+  C+  GI V AYSP
Sbjct: 174 VLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSP 215


>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
           Corynebacterium jeikeium K411|Rep: Putative
           oxidoreductase - Corynebacterium jeikeium (strain K411)
          Length = 285

 Score =  143 bits (347), Expect = 3e-33
 Identities = 84/203 (41%), Positives = 116/203 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P +++NDG T P   LG G     + D+   VR A    IE GYRHIDTAA+Y +EE VG
Sbjct: 9   PTLEMNDGKTTP--QLGLGVWQLSDEDTYTSVRAA----IETGYRHIDTAAIYGNEEAVG 62

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + +A+A+  G V REELF+TTKLWN   A  +   A  ES KKLG+DY+DLYL+H+P   
Sbjct: 63  RAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP--- 117

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    +++ +  M + +Q G A SIGV NF    +  L    +  P +NQIE++P
Sbjct: 118 ----CPQADSFVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAGH-TPAVNQIEIHP 172

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
             +Q    +  +  GI   A+SP
Sbjct: 173 GFSQAEQRSDNRDRGIVTEAWSP 195


>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Opitutaceae bacterium TAV2
          Length = 347

 Score =  143 bits (346), Expect = 4e-33
 Identities = 79/230 (34%), Positives = 125/230 (54%), Gaps = 13/230 (5%)
 Frame = +2

Query: 44  TLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRH 223
           T T  L      + P   L  G  +P + +GT      +  +  EV  +VY A E GYRH
Sbjct: 3   TETATLAPIDPAKIPQRTLASGARMPAIGMGT---FGSDHAAPGEVAASVYAAAELGYRH 59

Query: 224 IDTAAVYQDEEQVGQGIAEAI-ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLG 400
            D AAVY +E ++G      + +N  + RE+L++T+KLWNDKHA   V+PA ++SL+ LG
Sbjct: 60  FDCAAVYSNEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLG 119

Query: 401 LDYIDLYLIHFPI-----------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVS 544
           LDY+DLYLIH+P            +  PD  P  + ++++TW+ ++     GL R IG S
Sbjct: 120 LDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTS 179

Query: 545 NFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           N    ++  L+ ++ +RP +N++E++P   Q  L  + +   I  + Y P
Sbjct: 180 NMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCP 229


>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
           Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 316

 Score =  143 bits (346), Expect = 4e-33
 Identities = 87/212 (41%), Positives = 119/212 (56%), Gaps = 11/212 (5%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I   +G T+P +  GT R       S +EV +A+  A+EAGYRHIDTA VY +E+ +G+ 
Sbjct: 7   ITFENGTTMPALGFGTWRA------SDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKV 60

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + E +  G VTR+ELF+ TKL         V   L+ SL  L L+Y+DLY +H P     
Sbjct: 61  LKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPE 120

Query: 452 DDSP----DNIDYLET-------WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 598
            D P    D +  LET       W+ M++  + GLAR+IG+SNFN  QI R++ N  I+P
Sbjct: 121 VDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKP 180

Query: 599 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
              QIE +    Q  LV  C++ GI V AYSP
Sbjct: 181 ANLQIENHIYLQQPELVKFCKANGITVTAYSP 212


>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
           Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 315

 Score =  142 bits (345), Expect = 6e-33
 Identities = 81/214 (37%), Positives = 119/214 (55%), Gaps = 6/214 (2%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA      +LN G   P V LGT +       S   V  AV  A++ GYRHID A +Y +
Sbjct: 1   MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E+++G  + +   + +V RE+LF+T+KLW   H    V  AL  +LK L L+Y+DLYLIH
Sbjct: 55  EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114

Query: 431 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
           +P   K       P+N   +D   TW+ M+     G AR+IGVSNF+  ++  L+  + +
Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            P +NQ+E +P+  Q  L   C+S G+ + AYSP
Sbjct: 175 PPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSP 208


>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
           <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
           Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
           + NADPH - Aspergillus niger
          Length = 345

 Score =  142 bits (345), Expect = 6e-33
 Identities = 89/213 (41%), Positives = 120/213 (56%), Gaps = 13/213 (6%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN G  +P V LGT +         DEVR AV  A++ GYRHID AAVY +E++VG G+
Sbjct: 8   KLNTGYDMPAVGLGTWQSKK------DEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
                +G V REE+F+T+KLWN  H  + V  A+ +SL  L  DY+DLYLIH+P+A +  
Sbjct: 62  R---LSG-VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYS 117

Query: 455 DS---PDN-----IDYL-----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 595
            +   P N     ID +     +TW  M+   + G  RSIGVSNF   +I  L+  + I 
Sbjct: 118 TTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKIT 177

Query: 596 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           P +NQIE +P   Q  L+      GI V  YSP
Sbjct: 178 PAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSP 210


>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
           reductase - Hordeum vulgare (Barley)
          Length = 320

 Score =  142 bits (345), Expect = 6e-33
 Identities = 82/206 (39%), Positives = 127/206 (61%), Gaps = 7/206 (3%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L  G+ +P V LGT R     SD+   VR A+    EAGYRH+DTAA Y  E++VG+G+ 
Sbjct: 18  LKSGHAMPAVGLGTWRAG---SDTAHSVRTAI---TEAGYRHVDTAAEYGVEKEVGKGLK 71

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 448
            A+  G + R++LFVT+K+W    A ++V PAL+ +LK L LDYIDLY IH+P   K   
Sbjct: 72  AAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA 130

Query: 449 --PDDSPDNIDY-LE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
             P ++ + +++ +E  W+ M++  + GL + IGV N+  T++ RL+ ++ I P + Q+E
Sbjct: 131 HMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQME 190

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++P    + +   C+  GI V AYSP
Sbjct: 191 MHPGWKNDKIFEACKKHGIHVTAYSP 216


>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinobacteria (class)|Rep: 2,5-didehydrogluconate
           reductase - Arthrobacter sp. (strain FB24)
          Length = 276

 Score =  142 bits (344), Expect = 7e-33
 Identities = 85/204 (41%), Positives = 121/204 (59%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           +P I+LNDG+ IP + LGT        D   +V  AV  A+E GYRHIDTA  Y +E+ V
Sbjct: 4   SPVIELNDGHRIPQIGLGTW-----PLDD-HQVAAAVVNAVEGGYRHIDTAVKYGNEKGV 57

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           G GI    ++GL  R ELF+TTKL  +   +D+ V  L  SLK+LGLDY+DL LIH+P+ 
Sbjct: 58  GNGIR---SSGL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL- 112

Query: 443 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 622
                 P   +++ TW+  +  +  G  RSIGVSNF    + RL++   + P +NQI+V+
Sbjct: 113 ------PRRDEFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQVS 166

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P  T+   +A+ +  GI   +YSP
Sbjct: 167 PAITRIVDIAYNRRHGIVTESYSP 190


>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
           Lin2739 protein - Listeria innocua
          Length = 283

 Score =  141 bits (342), Expect = 1e-32
 Identities = 84/202 (41%), Positives = 117/202 (57%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++LN+G  +PI+  GT + T        E  QAV  AI AGYRHIDTA  Y +EE VG+G
Sbjct: 4   VKLNNGIEVPILGFGTYQIT-----DAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRG 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           IA   A+G V R+ELF+TTK+W +  +   V+ +   SLK+LGLDYIDL LIH P     
Sbjct: 59  IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN--- 111

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                  D    W  M++ +  G  ++IGVSNF   ++  L + + I P +NQIE+NP  
Sbjct: 112 -------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQ 164

Query: 632 TQEPLVAHCQSLGIAVMAYSPF 697
            Q   +   +  G+AV A++PF
Sbjct: 165 QQSKNIEALRKEGVAVEAWAPF 186


>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
           Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
           reductase - Tropheryma whipplei (strain Twist)
           (Whipple's bacillus)
          Length = 283

 Score =  140 bits (340), Expect = 2e-32
 Identities = 81/204 (39%), Positives = 118/204 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + L DG +IP   LGT      E+ S+      V  AIE GYRHIDTA++Y +E +VG
Sbjct: 10  PSVLLGDGVSIPQFGLGTYELPPNEASSV------VQSAIELGYRHIDTASLYANEREVG 63

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           +    AIA+  + REE FVTTKLWN    + +   A + SL  L LDY+DLYLIH+P   
Sbjct: 64  R----AIASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWPC-- 115

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P +  Y+  W+ + + ++ G A+S+GVSNF +  I ++    +  P +NQIE++P
Sbjct: 116 -----PPSELYINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHP 170

Query: 626 TNTQEPLVAHCQSLGIAVMAYSPF 697
              Q  LV  C++ GI + ++ PF
Sbjct: 171 WLQQRELVLSCRNDGIQIESWGPF 194


>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
           Benzil reductase - Bacillus subtilis
          Length = 276

 Score =  140 bits (340), Expect = 2e-32
 Identities = 78/201 (38%), Positives = 127/201 (63%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++L++G  +P   LG  +      ++ +E  ++V  AI+ GYR IDTAA+Y++EE VG G
Sbjct: 9   VKLHNGVEMPWFGLGVFK-----VENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIG 63

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I E+   G V REELF+T+K+WN+    +  + A ++SL++L LDY+DLYLIH+P   K 
Sbjct: 64  IKES---G-VAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK- 118

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                   Y +TW+ ++   + G  R+IGVSNF    +  L+ ++ I+P++NQ+E +P  
Sbjct: 119 --------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRL 170

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
           TQ+ L  +C++ GI + A+SP
Sbjct: 171 TQKELRDYCKAQGIQLEAWSP 191


>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
           Orconectes limosus|Rep: Aldoketoreductase-like protein -
           Orconectes limosus (Spinycheek crayfish)
          Length = 336

 Score =  140 bits (340), Expect = 2e-32
 Identities = 82/220 (37%), Positives = 114/220 (51%), Gaps = 10/220 (4%)
 Frame = +2

Query: 65  AAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVY 244
           A    + P I LN G+ IP++ LGTG        S + V   +  A+E GYRH D+AA Y
Sbjct: 5   AGAMTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYY 64

Query: 245 QDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 424
            +E  +GQ +   I+ G V REELF+TTKL    +    V   LQ+SL  L L Y+DLYL
Sbjct: 65  GNEAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYL 124

Query: 425 IHFPIATKPDD----SPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRL 574
           +H+P      D    S D +      D    W+ M+     G  ++IG+SNFNA Q+ R+
Sbjct: 125 VHYPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRI 184

Query: 575 VSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +    +RP + Q+EV+    Q  L A C    I V A+ P
Sbjct: 185 IKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCP 224


>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
           str. PEST
          Length = 310

 Score =  140 bits (340), Expect = 2e-32
 Identities = 82/214 (38%), Positives = 119/214 (55%), Gaps = 12/214 (5%)
 Frame = +2

Query: 89  CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 268
           CI L+D ++I +  +G G  +   +D     ++A+  AI+ GYR  DTA  Y +E  VG+
Sbjct: 6   CINLSDQHSIALPTIGLGTYSILGADG----KEAIRTAIDVGYRMFDTAVAYGNEAIVGE 61

Query: 269 GIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 442
            I E I     +TR++ F+ +KL    H +D V    + +L +LG+DY+DLYL+H P+A 
Sbjct: 62  AIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVAL 121

Query: 443 ----------TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
                     TK +   D+I   E W G++   Q GL RSIGVSNFN  QI  L+S++ I
Sbjct: 122 QSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASI 181

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            P +NQIE +    Q P+   CQ   I VM Y+P
Sbjct: 182 VPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTP 215


>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
           n=39; cellular organisms|Rep: NADPH-dependent aldose
           reductase GRE3 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 327

 Score =  140 bits (340), Expect = 2e-32
 Identities = 87/223 (39%), Positives = 129/223 (57%), Gaps = 21/223 (9%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN+G  +P+V LG  +   K   +       +Y AI+ GYR  D A  Y +E++VG+G
Sbjct: 5   VTLNNGLKMPLVGLGCWKIDKKVCAN------QIYEAIKLGYRLFDGACDYGNEKEVGEG 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 442
           I +AI+ GLV+R+++FV +KLWN+ H  D V  AL+++L  +GLDY+DLY IHFPIA   
Sbjct: 59  IRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118

Query: 443 ------------TKPDD------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 568
                       T  DD      +  ++  ++T++ +++    GL +SIGVSNF  + I 
Sbjct: 119 VPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQ 178

Query: 569 RLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
            L+    I+PV  QIE +P  TQE LV  C+   I V+AYS F
Sbjct: 179 DLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSF 221


>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG03517.1 - Gibberella zeae PH-1
          Length = 364

 Score =  140 bits (339), Expect = 3e-32
 Identities = 81/222 (36%), Positives = 130/222 (58%), Gaps = 3/222 (1%)
 Frame = +2

Query: 38  IITLTCLLNAAMAVQAPCIQLNDGNTI-PIVALGTGRGTAKESDSIDEVRQAVYWAIEAG 214
           ++T T L  A     A   + N   T+  I A G G   A +      V  AV +A++ G
Sbjct: 31  LVTYTILSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLAGKG----VVVPAVEYALKGG 86

Query: 215 YRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKK 394
           YRHIDTA ++++E++VG+GI    A+G V+R+E++VT KLWN  H  + V  A++ S+  
Sbjct: 87  YRHIDTALIWRNEDEVGKGIK---ASG-VSRDEIWVTGKLWNTDHRPELVRKAIETSIAN 142

Query: 395 LGLDYIDLYLIHFPIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 568
           LG++Y+DLYLIH+P+A  P+  D  +N   ++TW+ M++  + GL R+IG SNF    I 
Sbjct: 143 LGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDIN 202

Query: 569 RLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +++  + I+P  ++ E +P   Q+  V   +   I V+A SP
Sbjct: 203 KILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASP 244


>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
           Lmo2592 protein - Listeria monocytogenes
          Length = 283

 Score =  140 bits (338), Expect = 4e-32
 Identities = 84/202 (41%), Positives = 122/202 (60%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++LN+G  +PI+    G GT + +D+  E   AV  AI+AGYRHIDTA  Y +EE VG+G
Sbjct: 4   VKLNNGVEVPIL----GFGTYQITDAA-EAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRG 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           IA   A+G V R+ELF+TTK+W +  +   V+ +   SLK+LGLDY+DL LIH P     
Sbjct: 59  IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN--- 111

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                  D    W  M++ +  G  R+IGVSNF+  ++  L + + + P +NQIEVNP  
Sbjct: 112 -------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQ 164

Query: 632 TQEPLVAHCQSLGIAVMAYSPF 697
            Q   +A  +  G+A+ A++PF
Sbjct: 165 QQTANLAILRKEGVAIEAWAPF 186


>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
           Bifidobacterium|Rep: Dehydrogenase or reductase protein
           - Bifidobacterium longum
          Length = 289

 Score =  139 bits (337), Expect = 5e-32
 Identities = 83/203 (40%), Positives = 117/203 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I L DG++IP V LG  R    + + +  V ++   A+EAGYRHID AA Y +E  VG
Sbjct: 12  PDIALKDGHSIPQVGLGVLR---IDDEGVVPVVES---ALEAGYRHIDGAAGYNNEAGVG 65

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + +A +  N    RE L+VTTKL + +   D  + A   SLK L LDY+D+Y+IH+P   
Sbjct: 66  RALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWP--- 122

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
               +P +    +TW+     R  G+AR++GV NF    + RL   +   P +NQIE++P
Sbjct: 123 ----TPFDWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHP 178

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
           T  Q  +VA C+  GIAV AYSP
Sbjct: 179 TWQQREVVAFCKEHGIAVEAYSP 201


>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
           CG2767-PA - Drosophila melanogaster (Fruit fly)
          Length = 329

 Score =  138 bits (335), Expect = 9e-32
 Identities = 82/219 (37%), Positives = 120/219 (54%), Gaps = 13/219 (5%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           V    +  N+G  +P++ +GT +       S +E+  A+  A+EAGYRHIDTA VY +E+
Sbjct: 2   VNTKFLTFNNGEKMPVIGIGTWQA------SDEEIETAIDAALEAGYRHIDTAPVYGNEK 55

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
            +G+ +   +  G V REELF+ TK+    +   +V P +++SL+ L LDY+DLYL+H P
Sbjct: 56  AIGRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTP 115

Query: 437 IATK-PDDSPDNID------------YLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
                 +D    +D            +   W  M+   + GL +SIGVSNF+  Q+ RL+
Sbjct: 116 FTININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLL 175

Query: 578 SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            N  IRP  NQIE +    Q  LV  C+S  I V AYSP
Sbjct: 176 KNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSP 214


>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 286

 Score =  138 bits (333), Expect = 2e-31
 Identities = 81/207 (39%), Positives = 118/207 (57%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           +Q P + LN+G  +PI+  G  +   ++++      + VY AI+ GYR IDTAA Y +EE
Sbjct: 1   MQVPKVTLNNGVEMPILGYGVFQIPPEKTE------ECVYEAIKVGYRLIDTAASYMNEE 54

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
            VG+ I  AI  G+V REELFVTTKLW      +    A ++SLKKL L+YIDLYLIH P
Sbjct: 55  GVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114

Query: 437 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
                       D    W+ M++  + GL R+IGVSNF   ++  L+ +  I P +NQIE
Sbjct: 115 FG----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIE 164

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           ++P   ++  +   ++  I   A+ PF
Sbjct: 165 IHPFYQRQEEIEFMRNYNIQPEAWGPF 191


>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
           n=2; Parasitella parasitica|Rep:
           4-dihydromethyltrisporate dehydrogenase - Parasitella
           parasitica
          Length = 321

 Score =  138 bits (333), Expect = 2e-31
 Identities = 82/191 (42%), Positives = 105/191 (54%), Gaps = 17/191 (8%)
 Frame = +2

Query: 176 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 355
           +    +Y AI+ GYR  D A  Y +E +VG+GI +AI  GLV REELF+ TKLWN  H++
Sbjct: 29  DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88

Query: 356 DQVVPALQESLKKLGLDYIDLYLIHFPIATK---------PDDSPDNIDYL--------E 484
             V  A    LK  GL+Y DLYLIHFPI  +         P+    + D L        E
Sbjct: 89  QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148

Query: 485 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQS 664
            W  M+   Q  L R+IGV+NFN   I  L+S + I+P + QIE++P   QE LV   Q 
Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQE 208

Query: 665 LGIAVMAYSPF 697
            GI V AYS F
Sbjct: 209 QGIQVTAYSSF 219


>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
           Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
           Kineococcus radiotolerans SRS30216
          Length = 289

 Score =  137 bits (332), Expect = 2e-31
 Identities = 87/207 (42%), Positives = 120/207 (57%)
 Frame = +2

Query: 74  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 253
           A+  P I LNDG  IP   LG G    +  D+     QAV  A++ GYRHIDTA +Y +E
Sbjct: 9   AMTVPTILLNDGREIP--QLGFGVFQIEPGDTA----QAVKTALDLGYRHIDTAQMYGNE 62

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
            +V QGIA++   G V R+E++VT+KL N  H  D    A+ +S++KL    IDLYLIH+
Sbjct: 63  AEVAQGIADS---G-VPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHW 117

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
           P+ T         D++ TW+ +++AR  G  RSIGVSNF    + RL   + + P +NQI
Sbjct: 118 PLPTLYGG-----DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQI 172

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           EV+P    E +  HC    I V A+SP
Sbjct: 173 EVHPYFGNEEVRRHCGEHQIGVEAWSP 199


>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 360

 Score =  137 bits (332), Expect = 2e-31
 Identities = 77/186 (41%), Positives = 116/186 (62%), Gaps = 1/186 (0%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G GT     S +   +AV +AIE GYR ID AAVY +E  VG+GI E +    + RE+++
Sbjct: 43  GFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIW 102

Query: 320 VTTKLWNDKH-ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 496
           VT+KLWND H + + V   L ++L+ LGL+Y+DLYLIH+PI     +   N+D+++T++ 
Sbjct: 103 VTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFS-SNGAKNLDHVQTYKS 161

Query: 497 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIA 676
           M    +     +IGVSNF+  Q+  +VS   I P ++Q+E++P   Q   VA  ++LGI 
Sbjct: 162 MISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIK 219

Query: 677 VMAYSP 694
           + AYSP
Sbjct: 220 MTAYSP 225


>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
           reductase family - Enterococcus faecalis (Streptococcus
           faecalis)
          Length = 279

 Score =  137 bits (331), Expect = 3e-31
 Identities = 79/204 (38%), Positives = 115/204 (56%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           A  + LN+G  IP    G G G  +  D  +E  + V   I  GYR IDTA +Y +E   
Sbjct: 6   ADTVTLNNGTKIP----GMGLGVFQIPD--EETAKVVEEGIINGYRLIDTAQIYGNESGT 59

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           G GI   +A   + RE+LFVT+K+WN   + D+ + A  +SL++LGLDY+DLYLIH+   
Sbjct: 60  GAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHW--- 116

Query: 443 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 622
                 P N  Y E+WQ ++     G  ++IGVSNF    +  L+S + + PVINQ+E++
Sbjct: 117 ------PGNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELH 170

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P   Q+ +   C+   I V A+SP
Sbjct: 171 PKLDQKEVRDFCEKHDIKVQAWSP 194


>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
           Aldo/keto reductase - Kineococcus radiotolerans SRS30216
          Length = 343

 Score =  136 bits (330), Expect = 4e-31
 Identities = 81/215 (37%), Positives = 119/215 (55%), Gaps = 12/215 (5%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P  +L  G T+P + +GT  G+ + S +  EV  AV  A+ AGYR +D AAVY +E QVG
Sbjct: 14  PRRELRGGATVPAIGIGTF-GSDRYSPA--EVAAAVAGAVAAGYRLVDCAAVYGNEAQVG 70

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI-- 439
           + +A A+A G V R+ELFV +K+WND HA    V ++  SL+ L LD++D   +H+P   
Sbjct: 71  EALAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPN 129

Query: 440 ---------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
                    A  P   P D+  YL  W  ++     GL R +G SN    ++  L+ ++ 
Sbjct: 130 HHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDAR 189

Query: 590 IRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           I P +N++E++P   Q  L AHC   GI  + YSP
Sbjct: 190 IPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSP 224


>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
           Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 281

 Score =  136 bits (330), Expect = 4e-31
 Identities = 82/203 (40%), Positives = 117/203 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + LN+G  IP +  G  +   +E+  I E       A+EAGYRHIDTAA Y++E  VG
Sbjct: 10  PQLTLNNGVKIPQLGFGVFQVPPEETQRIVED------ALEAGYRHIDTAAAYRNEAGVG 63

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
             I+   A+G + RE++F+TTKL N +        A Q S K LG++++DLYLIH+P+  
Sbjct: 64  AAIS---ASG-IPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPV-- 115

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    Y E W+ M+        R+IGVSNF    +  L+  + + P +NQ+E++P
Sbjct: 116 -----PSQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHP 170

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
           T  Q+ L A C+ LGIAV AYSP
Sbjct: 171 TFQQQELAAKCRELGIAVEAYSP 193


>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
           aegypti|Rep: Aldo-keto reductase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 284

 Score =  136 bits (330), Expect = 4e-31
 Identities = 80/208 (38%), Positives = 122/208 (58%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+ +AP ++LN+G  +P++ LGT    +KE + ++ ++ A    I+AGYRHIDTA  YQ+
Sbjct: 1   MSPKAPMVKLNNGLEMPVLGLGTW--LSKEGEGVEAIKAA----IDAGYRHIDTAYFYQN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E++VG+ I   I  G+V RE+LFVTTK                       +D+    L+ 
Sbjct: 55  EKEVGEAIRAKIEEGVVCREDLFVTTKF----------------------IDWDTKNLMP 92

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
           +    K   S  ++DY++TW+ M+   + G  +SIGVSNFN+ QITRL++   I+PV NQ
Sbjct: 93  YDADGKLQFS--DVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQ 150

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +E NP+  Q  L   C++L I + AYSP
Sbjct: 151 VECNPSLNQRKLTEFCKNLDITLTAYSP 178


>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
           djamor|Rep: Reductase AKOR2 - Pleurotus djamor
          Length = 306

 Score =  136 bits (330), Expect = 4e-31
 Identities = 84/217 (38%), Positives = 124/217 (57%), Gaps = 14/217 (6%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I LN G  +P +ALG   G  +E  +  + ++    A+++GYRHIDTA +Y  E+ VG
Sbjct: 5   PPIVLNTGARMPALALGGWAGLTEEERT--QAKEWFLTALKSGYRHIDTAQIYYTEKSVG 62

Query: 266 QGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
             I E+   G + REELF+TTKL WN  H+R  V  + Q+SL+ LG +YIDLYL+HFP  
Sbjct: 63  NAIRES---G-IPREELFITTKLPWNH-HSR--VAESFQKSLENLGTEYIDLYLVHFPQR 115

Query: 443 TKPD---DSPDNID----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 583
              D   D P N D            + W  ++     G  ++IGVSN++   +  L+  
Sbjct: 116 VFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKT 175

Query: 584 SYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           + + P +NQ+E++P   Q  L+A+C+  GIAV AY+P
Sbjct: 176 AKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTP 212


>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 310

 Score =  136 bits (329), Expect = 5e-31
 Identities = 76/215 (35%), Positives = 129/215 (60%), Gaps = 4/215 (1%)
 Frame = +2

Query: 59  LNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAA 238
           L AA+      ++LN+G  +P+V +GT +   +E      +++ +  +   G+R IDTA 
Sbjct: 15  LEAALTPTIRDLRLNNGYDMPLVGIGTYKVRGREV-----IKRVIDESFAVGFRSIDTAV 69

Query: 239 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYID 415
           VY++EE +G  + E +    + RE++F+T+KL  +D    D++  ++++SLK L   Y+D
Sbjct: 70  VYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLD 129

Query: 416 LYLIHFPIATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-S 586
           LYLIH+P A++  ++SPDN    + TW  + + +Q GL RSIGVSN+    +  L+ + S
Sbjct: 130 LYLIHWPGASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCS 189

Query: 587 YIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
            ++P +NQ+E +P   Q+ L+  C   GI V AYS
Sbjct: 190 GVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYS 224


>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 295

 Score =  136 bits (329), Expect = 5e-31
 Identities = 74/201 (36%), Positives = 118/201 (58%), Gaps = 1/201 (0%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L +G+ +P+  LGT +  +KE     E+   +  A++ GYRHIDTA +Y++E+Q+G  +
Sbjct: 9   ELCNGSKLPVFGLGTYKVVSKE-----EMVTFLRTALDLGYRHIDTAIMYENEKQIGDAL 63

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
            E    G   RE+LF+ TKL+++K+ +  V   +++SL+ L  +YIDLYL+H+  +   D
Sbjct: 64  QEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121

Query: 455 DSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                +    + W   ++  Q GL R+IG+SNFN   +  L S   I+PV+NQIEVN   
Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYC 181

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  L+  C+ L + V AY P
Sbjct: 182 QQPRLLEFCKKLNLHVTAYCP 202


>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
           n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
           reductase family - Lactobacillus acidophilus
          Length = 289

 Score =  136 bits (329), Expect = 5e-31
 Identities = 83/204 (40%), Positives = 114/204 (55%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I+LNDGN IP +  G       +  + DE  +AV  AI  GYR IDTA  Y ++  VG
Sbjct: 5   PKIKLNDGNEIPQLGFGVF-----QISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVG 59

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
               EAI N  V R+++F+TTKLW      ++   A+ E LK+LG DYID+ L+H     
Sbjct: 60  ----EAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG- 114

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                    D    W+ ++DA++ G  +SIGVSNF   Q+  L   S ++PV+NQIEVNP
Sbjct: 115 ---------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNP 165

Query: 626 TNTQEPLVAHCQSLGIAVMAYSPF 697
              +EP V   Q   +AV A++PF
Sbjct: 166 WFQREPEVKWNQKDDVAVEAWAPF 189


>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
           Ruminococcus obeum ATCC 29174|Rep: Putative
           uncharacterized protein - Ruminococcus obeum ATCC 29174
          Length = 263

 Score =  136 bits (329), Expect = 5e-31
 Identities = 79/185 (42%), Positives = 110/185 (59%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G G  K +D++ E   A+  A++ GYR +DTA+ Y++EE VG GIA+    G V R++LF
Sbjct: 5   GLGLYKTTDAV-EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---G-VPRKDLF 59

Query: 320 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 499
           +TTK+WN+      V  A Q SL +LGLDYIDLYLIH+P+            +L TW+ M
Sbjct: 60  ITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPVPG---------CFLNTWKDM 110

Query: 500 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAV 679
           +   + G A SIGVSNF    +  L   S I P +NQIE +P    + L+ +CQ+  I V
Sbjct: 111 EKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQV 170

Query: 680 MAYSP 694
            AY+P
Sbjct: 171 QAYAP 175


>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 339

 Score =  136 bits (328), Expect = 6e-31
 Identities = 73/218 (33%), Positives = 124/218 (56%), Gaps = 16/218 (7%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           A  + LN G  +P++  GT +    ++ + + VR A    +EAGYRHID+A  ++++E+V
Sbjct: 4   ADTVTLNSGYEMPVIGYGTWQ--LPKNLAAERVRDA----LEAGYRHIDSALSFKNQEEV 57

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
             GI +      V REELF+++K+WN  H+R++ +  + E L+     Y+DL +IH+P  
Sbjct: 58  AAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFG 117

Query: 443 TKPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 574
              D+ P                 ++DYLETW+ ++DA + G  RSIG++NFN  Q+ ++
Sbjct: 118 WAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQV 177

Query: 575 VSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAY 688
            +   I+P + Q+E+NP   QE +   C+  GI + A+
Sbjct: 178 WTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAF 215


>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
           Actinomycetales|Rep: Putative oxidoreductase -
           Streptomyces coelicolor
          Length = 277

 Score =  135 bits (327), Expect = 8e-31
 Identities = 85/208 (40%), Positives = 119/208 (57%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+ + P I LN+G  +P +    G G  +  D  D+ + AV  A+EAGYR IDTAA+Y +
Sbjct: 1   MSSKVPPIILNNGVEMPQL----GFGVWQVPD--DDAQTAVALALEAGYRSIDTAAIYGN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           EE  G+ IA   A+GL  RE+LFVTTKLWN     D  + A   S+ KLGL+Y+DLYLIH
Sbjct: 55  EEGTGRAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIH 110

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
           +P+  K         Y++T++  +     G  R+IGVSNF    + RL + + + P +NQ
Sbjct: 111 WPMPAKE-------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IE++P   Q          GIA  A+SP
Sbjct: 164 IELHPHLQQHAAREVHAEQGIATEAWSP 191


>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
           Oxidoreductase - Xanthomonas campestris pv. campestris
           (strain 8004)
          Length = 267

 Score =  135 bits (327), Expect = 8e-31
 Identities = 89/194 (45%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
 Frame = +2

Query: 113 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 292
           T+P   LGT R   K+   ID VR A    +  GYR IDTA +Y +E QVGQ IA+A   
Sbjct: 2   TVPAFGLGTFR--LKDQVVIDSVRNA----LALGYRAIDTAQIYDNEAQVGQAIADA--- 52

Query: 293 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 472
           G V R++LFVTTK+W D+ +RD + P+LQESL+KLG DY+DL LIH+P    P D     
Sbjct: 53  G-VPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP---SPKDQVPMR 108

Query: 473 DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI--NQIEVNPTNTQEPL 646
           +YLE    + DA+  GL R+IGVSNF    +TR          I  NQIEV+P      L
Sbjct: 109 EYLE---ALADAKAQGLTRAIGVSNFTIA-LTRQAIEILGADAIATNQIEVHPYLQNRTL 164

Query: 647 VAHCQSLGIAVMAY 688
           +A  +  GI V +Y
Sbjct: 165 IAFLREQGIHVTSY 178


>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
           Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
           sp. (strain CCS1)
          Length = 276

 Score =  135 bits (327), Expect = 8e-31
 Identities = 79/203 (38%), Positives = 118/203 (58%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I+ +DG  IP V  G  +         D   + V  AIE GYR ID A +Y +E  +G
Sbjct: 5   PVIKFHDGAQIPQVGFGIWQVPQ------DIAGETVRSAIEIGYRMIDGAYLYMNEAGLG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           +G+    A+GL  R+E+FVTTK+WN++    +   +++ SLK +G++ +DL LIH+P+  
Sbjct: 59  EGLR---ASGL-PRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV-- 112

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    YLETW+  QD R  GL RSIG SNFNA  + R+++ +   PV+NQIE+NP
Sbjct: 113 -----PSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNP 167

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  + A  ++ G+   A++P
Sbjct: 168 MLQQPEMRAVHKAHGVVTQAWTP 190


>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Opitutaceae bacterium TAV2
          Length = 334

 Score =  135 bits (327), Expect = 8e-31
 Identities = 83/203 (40%), Positives = 116/203 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + L+DG +IP + LG  +      D      QA   A  AGYR IDTA +Y +EE VG
Sbjct: 60  PTLPLSDGTSIPQLGLGVWQ---MPDDGAGVPIQA---AFNAGYRAIDTAPIYGNEEGVG 113

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + I    A+GL  R+EL++TTK+WN     D  + A++ESL +L L+Y+DLYLIH+P+  
Sbjct: 114 RAIR---ASGL-PRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV-- 167

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    Y++TW+ +   +  GLARSIGVSNF    + RL   + I PV+NQ+E++P
Sbjct: 168 -----PKIDRYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHP 222

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  L A      I   A+SP
Sbjct: 223 RLQQHELRAFHAKHRIVTEAWSP 245


>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
           Aldehyde reductase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 313

 Score =  135 bits (326), Expect = 1e-30
 Identities = 73/203 (35%), Positives = 113/203 (55%), Gaps = 12/203 (5%)
 Frame = +2

Query: 122 IVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLV 301
           I ALG G   A  + +I   R A    + AG+RH D A  Y++E +VG+ +    A G +
Sbjct: 20  IPALGFGTLIADPALTITATRDA----LAAGFRHFDCAERYRNEREVGEALRAGRAAGNI 75

Query: 302 TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD----- 466
            REE+FVTTKLWN  H  ++V PA + SL +LGLDY+DLYLIH P A +P D  D     
Sbjct: 76  AREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQN 135

Query: 467 -------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                   +   ETW  +++    G  R+IG+S+ +  ++  +   + I+P + Q+E +P
Sbjct: 136 GSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHP 195

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              +  L+  C+  GI ++A++P
Sbjct: 196 YLPETELLEFCKRNGIVLLAFAP 218


>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
           SCB49|Rep: ARA1 - unidentified eubacterium SCB49
          Length = 280

 Score =  135 bits (326), Expect = 1e-30
 Identities = 72/200 (36%), Positives = 118/200 (59%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN+   IP +  GT + T     +I+ ++ A    I+AGY+HID AA+Y++E+ VG GI
Sbjct: 6   KLNNNINIPAIGFGTWQ-TPDGQTAINAIKTA----IDAGYKHIDAAAIYKNEKGVGLGI 60

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
            EA     + R++LFVT+K+WN++   +  + A   ++  L LDY+DLYLIH+P A    
Sbjct: 61  KEAN----IDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQF 116

Query: 455 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 634
           ++   ++  +TW  M+   + G  +++GVSNF    +T L+ ++ I+P +NQIE +P   
Sbjct: 117 ENWKQLNN-DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYM 175

Query: 635 QEPLVAHCQSLGIAVMAYSP 694
           Q+  V  C    I V  +SP
Sbjct: 176 QQDCVQFCNDNNIQVEGWSP 195


>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
           Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 289

 Score =  134 bits (325), Expect = 1e-30
 Identities = 77/207 (37%), Positives = 112/207 (54%)
 Frame = +2

Query: 74  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 253
           A+  P + L++G  IPI+ LGT        +++      +Y   E G RHIDTA  Y  E
Sbjct: 10  ALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAV------LYALQECGIRHIDTAKRYGCE 63

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
           E +G+ + E+   G V REEL+VTTKLW   +       A ++S  +LG+DY+DLYL+H+
Sbjct: 64  EALGKAVTES---G-VQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHW 119

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
           P +  P  S   +  LETW+ +++    GL R+IGVSNF    +  L  +  I P +NQ+
Sbjct: 120 PDSMVPGRSSQEV-RLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQV 178

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           E +P      LV HC+   I    Y P
Sbjct: 179 EFHPFQQPMKLVEHCRKENIVFEGYCP 205


>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
           Arabidopsis thaliana|Rep: Uncharacterized protein
           At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 283

 Score =  134 bits (325), Expect = 1e-30
 Identities = 77/207 (37%), Positives = 114/207 (55%), Gaps = 6/207 (2%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA      +LN G   P V LGT +       S   V  AV  A++ GYRHID A +Y +
Sbjct: 1   MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E+++G  + +   + +V RE+LF+T+KLW   H    V  AL  +LK L L+Y+DLYLIH
Sbjct: 55  EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114

Query: 431 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
           +P   K       P+N   +D   TW+ M+     G AR+IGVSNF+  ++  L+  + +
Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGI 673
            P +NQ+E +P+  Q  L   C+S G+
Sbjct: 175 PPAVNQVECHPSWRQTKLQEFCKSKGV 201


>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
           aldo/keto reductase family protein - Tetrahymena
           thermophila SB210
          Length = 297

 Score =  134 bits (325), Expect = 1e-30
 Identities = 74/208 (35%), Positives = 120/208 (57%), Gaps = 2/208 (0%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           V+ P +   +G +IP +  GT     +++D I  V +A    ++ GY HIDTA+VY++E+
Sbjct: 11  VKVPILNFREGGSIPQIGYGTYE--LRQNDCIIGVTEA----LKIGYTHIDTASVYRNEQ 64

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
            + + I    A G + RE+LF+T+K+   +   +Q   A+Q+ L +L + Y+D  LIH+P
Sbjct: 65  DIAKVIHNP-AYG-IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122

Query: 437 IATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
             +K P + P N    LETW+ + + R+ G+ + IGVSNFN   +  L+  S  +P +NQ
Sbjct: 123 GVSKLPPNDPKNAQIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQ 182

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            E++P    +  +  CQ  GI V AYSP
Sbjct: 183 FEIHPLCFNKKTIEFCQKNGILVEAYSP 210


>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15457-PA - Nasonia vitripennis
          Length = 388

 Score =  134 bits (323), Expect = 3e-30
 Identities = 83/231 (35%), Positives = 130/231 (56%), Gaps = 12/231 (5%)
 Frame = +2

Query: 38  IITLTCLLNAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGY 217
           ++ L  +L  A AV+   ++L+ G+ IP V LGT   T K    +DE+  A+  A+E GY
Sbjct: 10  LVVLAVVLPGAQAVEK--LKLSSGHEIPAVGLGTS--TIK----LDEMDNAISSALENGY 61

Query: 218 RHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKL 397
           RHIDTA  Y +E  +G+ + +    G   RE++F+T+KL +  +    V   L+ SLK L
Sbjct: 62  RHIDTAFSYDNEAAIGKILKKWFDKG-GKREDIFITSKLPSQGNRPQSVETYLKRSLKDL 120

Query: 398 GLDYIDLYLIHFPIATKP------------DDSPDNIDYLETWQGMQDARQLGLARSIGV 541
           GLDY+D+YLIH P A K             +D  D++D+   W+ M+   + G A+SIG+
Sbjct: 121 GLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGL 180

Query: 542 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           SNFN +Q+  + +N+ I+P   Q+E +    Q+ L   C+   I + AY+P
Sbjct: 181 SNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAP 231


>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
           family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
           oxidoreductase, aldo/keto reductase family - Entamoeba
           histolytica HM-1:IMSS
          Length = 307

 Score =  134 bits (323), Expect = 3e-30
 Identities = 86/207 (41%), Positives = 119/207 (57%), Gaps = 8/207 (3%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ-GI 274
           LN+G  +P + LGT            EV +AV  A+E GYR ID A  Y++E+++G+ GI
Sbjct: 8   LNNGKFMPAIGLGTWLAAP------GEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGI 61

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
              + N    REELFVT+KLW D+  R  +  +  ES++ L   Y+DLYLIH+PIA K D
Sbjct: 62  EPFLKNH--PREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVD 117

Query: 455 DS----PDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
            S    P++   +D  E WQ M+     GL +SIG+SNF   QI +++    I+PVINQ+
Sbjct: 118 ASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQV 177

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           E+N    Q  L   C+S  I V AY P
Sbjct: 178 ELNVYLQQNKLREVCKSYNIVVEAYRP 204


>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
           Pezizomycotina|Rep: Aldo/keto reductase family proteins
           - Aspergillus oryzae
          Length = 294

 Score =  133 bits (321), Expect = 5e-30
 Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKES--DSID-EVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           P ++LND  +IPI+  GTG    K++  DS++ E+ +A+  AI  GYRH+D A VY  E 
Sbjct: 10  PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69

Query: 257 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
           ++G  I E+   G + REELFVTTK+  +      +  A+ +SL+KL L+Y+DLYLIH P
Sbjct: 70  ELGVAIKES---G-IPREELFVTTKVITNIA---DIPSAIDQSLRKLQLNYVDLYLIHSP 122

Query: 437 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
              K D      +  + W  M+  +Q G A++IGVSN++ + +   +  + I PVINQIE
Sbjct: 123 FFAKSDG-----ELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +P   QE L+   +   I + +Y P
Sbjct: 178 HHPYLQQEELLRFQREKDIKIASYGP 203


>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=3; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 309

 Score =  132 bits (320), Expect = 6e-30
 Identities = 74/200 (37%), Positives = 124/200 (62%), Gaps = 16/200 (8%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 316
           G GT    D    ++ AV+ AIE +GYRH+D AA Y+++E +G+ ++E  A G V REE+
Sbjct: 8   GLGTFLAEDPA-ALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEV 66

Query: 317 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TKPDDS---------- 460
           ++T+K+WN KH  D +V  ++++LK+L L+Y+DL L+H+  A  ++ DD           
Sbjct: 67  WITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKI 126

Query: 461 -PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--YIRPVINQIEVNPTN 631
             +NID LETW+ M++   LGLA+ IGVSNF+  Q+ R+  +    I+P  NQ+E +   
Sbjct: 127 ITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYL 186

Query: 632 TQEPLVAHCQSLGIAVMAYS 691
            Q+P++ +     + +++Y+
Sbjct: 187 QQQPMLDYLTQRKMYMISYT 206


>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
           CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome F of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 324

 Score =  132 bits (320), Expect = 6e-30
 Identities = 85/217 (39%), Positives = 120/217 (55%), Gaps = 17/217 (7%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LNDG++IP + LGT       SD    V + VY AI+ GYRHIDTA +Y  E  VG+GI
Sbjct: 8   KLNDGHSIPALGLGTA------SDG--NVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
             AI   LV RE LFVTTK+W   + R  V  +L  SLK L LDY+DL L+H+P++   D
Sbjct: 60  KRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLAD 117

Query: 455 -DSPDNI----------------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 583
            D P  I                D++ T++ +++ +  G  +SIGVSN +   + RL+  
Sbjct: 118 SDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQ 177

Query: 584 SYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
               P +NQ E++P   Q+  +   +  GI V A+SP
Sbjct: 178 VKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSP 214


>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
           cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
           cuniculi
          Length = 301

 Score =  132 bits (319), Expect = 8e-30
 Identities = 78/210 (37%), Positives = 119/210 (56%), Gaps = 11/210 (5%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN+G  IP V LGT      E +++ E   A+  A+  GYRHIDTA +Y +E+ +G  +
Sbjct: 7   KLNNGKEIPTVGLGTW---GMEDEAVLE--GAIRNALSLGYRHIDTAFIYGNEKMIGNIL 61

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TK 448
            +    G+V R++LF+T+KLWN  H   +    L+ SL  L +DY+DLYLIH+P+     
Sbjct: 62  KKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTFDPA 119

Query: 449 PDDSPDN---------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 601
           PD + ++          D +  W+ M+    LGLA+SIG+SNF      +++    I P 
Sbjct: 120 PDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPA 179

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
             QIE++P   Q+ LV   +S GI V++YS
Sbjct: 180 AIQIELHPYLNQKELVEFMKSKGIQVISYS 209


>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
           dehydrogenases of different specificities; n=4;
           Pezizomycotina|Rep: Similarity: shows similarity to
           several dehydrogenases of different specificities -
           Aspergillus niger
          Length = 381

 Score =  132 bits (319), Expect = 8e-30
 Identities = 80/221 (36%), Positives = 122/221 (55%), Gaps = 19/221 (8%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN G  IP +  GT +          +V  AVY A++AGYRH+D A +YQ++ +V +G
Sbjct: 7   VTLNSGAQIPQLGFGTWQSAP------GQVGDAVYEALKAGYRHLDLATIYQNQREVAEG 60

Query: 272 IAEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 442
           I  A  +  GL  RE++F+T+KLWN +H    V  AL E L +L LDY+DLYL+H+P++ 
Sbjct: 61  IKRAYKDVPGL-KREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119

Query: 443 -TKPDDSP---------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 574
            T  +  P               D+I  ++TW+ M    +   AR++GVSN     +  +
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178

Query: 575 VSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPF 697
           ++ + + P +NQIE +P      L+ +CQ  GI V AYS F
Sbjct: 179 INATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAF 219


>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
           Mycoplasma gallisepticum
          Length = 289

 Score =  132 bits (318), Expect = 1e-29
 Identities = 72/186 (38%), Positives = 109/186 (58%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G GT K  D    V +AV  A+E GYRH+D A +Y+++  V QGI     +G V R+E+F
Sbjct: 26  GFGTYKLEDGKQTV-EAVKTALEVGYRHLDCAEIYENQLSVSQGIK---LSG-VNRKEIF 80

Query: 320 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 499
           +T+K+WND    +    A  + LK L L+Y+DL LIH+PI     D+   ++  +TW+ M
Sbjct: 81  ITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDNWQEVN-AQTWKAM 139

Query: 500 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAV 679
           ++    G  ++IG+SNF    I  L  ++ I P++NQ+E +P   Q  +V +CQ   I V
Sbjct: 140 EEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVV 199

Query: 680 MAYSPF 697
            A+SPF
Sbjct: 200 QAWSPF 205


>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
           Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
           protein - Erythrobacter sp. SD-21
          Length = 272

 Score =  132 bits (318), Expect = 1e-29
 Identities = 72/203 (35%), Positives = 117/203 (57%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + LNDG  IP   LG G    +E D+     QAV  AI+ GY  IDTAA+Y +E+ VG
Sbjct: 5   PTLNLNDGRQIP--QLGFGTWQMEEEDA----PQAVSTAIDVGYWLIDTAAIYGNEKGVG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           +G+ E          ++F+ TK+WND    D+ + A ++ L++LG +++D+ LIH+P   
Sbjct: 59  KGVGEW--------SDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC-- 108

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P+   +++TW+ + + R  G A+SIGVSNF    + R++  + + P +NQIE++P
Sbjct: 109 -----PEKDQFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHP 163

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
           +  Q  +    + LGI   ++SP
Sbjct: 164 SFQQRDMRKVHEDLGIVTQSWSP 186


>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
           reductase; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to aldose reductase -
           Strongylocentrotus purpuratus
          Length = 274

 Score =  131 bits (316), Expect = 2e-29
 Identities = 69/173 (39%), Positives = 102/173 (58%)
 Frame = +2

Query: 176 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 355
           +V  AV  AI+ GYRHID A VY +E +VG G+ E     +V RE++F+T+KLWN+KH  
Sbjct: 11  QVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHP 70

Query: 356 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 535
           D V  A   +LK L L Y+DLYL+H+P+A               +Q M+     G  ++I
Sbjct: 71  DDVEQACDITLKNLQLSYVDLYLMHWPMA---------------YQAMEKLVTSGKCKAI 115

Query: 536 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           G+SNF+   + R++  + I+P   Q+E++P  TQE L+  C+   + V AYSP
Sbjct: 116 GLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSP 168


>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=3; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 299

 Score =  131 bits (316), Expect = 2e-29
 Identities = 71/203 (34%), Positives = 116/203 (57%), Gaps = 2/203 (0%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I L++G  +P   LG+ R       S++EV   +  A++ GYRHIDTA +Y++E+ +G  
Sbjct: 10  ITLSNGQKMPAFGLGSSR-----VQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAA 64

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           +      G   RE++F+ TK  + K      +  ++E L+KL +DY+DL LIH P+A   
Sbjct: 65  LKTIFGEGKYKREDIFLVTKQASIKGV--SCLEIMKEQLQKLQVDYVDLLLIHVPLAAPS 122

Query: 452 DDSP--DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
           DD    ++    + W   ++   LGLA+ +GVSNFN   I  L++   I+P++NQIE++ 
Sbjct: 123 DDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHV 182

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
            N Q+ LV   + + I  +A+SP
Sbjct: 183 FNQQKNLVEFLKKVNIYPVAFSP 205


>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein -
           Bacteroides capillosus ATCC 29799
          Length = 287

 Score =  131 bits (316), Expect = 2e-29
 Identities = 77/201 (38%), Positives = 118/201 (58%), Gaps = 2/201 (0%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L++G +IP V    G GT K  D    V      AI  GYRH DTA+ Y  E  +GQ +A
Sbjct: 10  LSNGLSIPAV----GFGTYKTGDGDSAVLSN---AIAQGYRHFDTASFYGTETALGQAVA 62

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
           E+     + RE+ F+T+KLW  +   D  + A   +L++LG DY+DLYLIH+P   +PD 
Sbjct: 63  ESD----IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---RPDL 115

Query: 458 SPDNIDYL--ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
             ++   L  ETW+ ++   + GL R+IGVSNF    +  +++++ + P+++Q+E +P  
Sbjct: 116 ELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHPGY 175

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
           TQ+  VA CQ+  I V A+SP
Sbjct: 176 TQDEAVAFCQNHSILVEAWSP 196


>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
           coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
           coagulans 36D1
          Length = 273

 Score =  131 bits (316), Expect = 2e-29
 Identities = 72/199 (36%), Positives = 114/199 (57%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L +G  IP + LGT +    E+        AV +A++ GYRHIDTA  Y +EE VG+   
Sbjct: 10  LENGVAIPKIGLGTWQVPNGET-----TYHAVSFALKNGYRHIDTAYAYHNEESVGK--- 61

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
            A+ +  + R ++FVT+KL  +  + D+ +    E++   GL+ +DLYLIH P       
Sbjct: 62  -AVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKG 120

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 637
           +    + +E W+ M++  + G  R+IGVSNF+ + +  ++ N+ I+P++NQI     +TQ
Sbjct: 121 ADYTKENIEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQ 180

Query: 638 EPLVAHCQSLGIAVMAYSP 694
           E + A CQ  GI V AYSP
Sbjct: 181 EDVTAFCQDNGILVEAYSP 199


>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
           reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
           NADH/NADPH dependent indole-3-acetaldehyde reductase
           AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
          Length = 284

 Score =  131 bits (316), Expect = 2e-29
 Identities = 83/200 (41%), Positives = 109/200 (54%), Gaps = 4/200 (2%)
 Frame = +2

Query: 107 GNTIPIVALGTGRGT-AKESDSIDE-VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAE 280
           G  IP+ A G G     KE   I+  +  +V  A+ AG+ HID A VY +EE+VG  + E
Sbjct: 7   GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKE 66

Query: 281 AIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 460
           A     V R +LF+T+K+    H  D +  AL ESL+KLG DY+DLYL+H PI       
Sbjct: 67  AN----VPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEKKI 119

Query: 461 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT--NT 634
           P +    E W+ M+ A   GL  S+GVSNF    +  L+  S I P +NQIE +P     
Sbjct: 120 PIS----EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKA 175

Query: 635 QEPLVAHCQSLGIAVMAYSP 694
            +PLV  CQS GI V  Y P
Sbjct: 176 AKPLVEFCQSKGIIVEGYGP 195


>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
           chain; n=3; Saccharomycetaceae|Rep: D-arabinose
           dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 344

 Score =  131 bits (316), Expect = 2e-29
 Identities = 86/222 (38%), Positives = 121/222 (54%), Gaps = 23/222 (10%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IP + LGT    A   + + E +QAV  AI+AGYRHIDTA  Y+ E  VG+ I 
Sbjct: 27  LNNGVRIPALGLGT----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP------- 436
           E + +G + RE+LF+TTK+W      D+V  +L ESLK LGL+Y+DL L H+P       
Sbjct: 83  ELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140

Query: 437 --------IATKPDDSPDNI-----DYLETWQGMQDA---RQLGLARSIGVSNFNATQIT 568
                   + T  DDS   +     DYLET++ ++           R+IGVSNF+   + 
Sbjct: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200

Query: 569 RLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           RL+    ++P +NQ+E +P   Q  L   C    I + AYSP
Sbjct: 201 RLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSP 242


>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
           reductase family 1, member B10, partial; n=1; Macaca
           mulatta|Rep: PREDICTED: similar to aldo-keto reductase
           family 1, member B10, partial - Macaca mulatta
          Length = 275

 Score =  130 bits (315), Expect = 2e-29
 Identities = 75/190 (39%), Positives = 111/190 (58%), Gaps = 8/190 (4%)
 Frame = +2

Query: 149 TAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTT 328
           T K    + +V++AV  AI+AGYRHID A VYQ+E +VG+ I E I    V RE+LF+ +
Sbjct: 38  TRKPKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVS 97

Query: 329 K------LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETW 490
           K      LW     R  V  A +++LK L L Y+D+YLIH+P               + +
Sbjct: 98  KVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWP---------------QGF 142

Query: 491 QGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLVAHCQS 664
           + M++    GL +++G+SNFN  QI +L++   +  +PV NQ+E +P  TQE L+ +C S
Sbjct: 143 KAMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS 202

Query: 665 LGIAVMAYSP 694
            GI + AYSP
Sbjct: 203 KGITITAYSP 212


>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_22, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 360

 Score =  130 bits (315), Expect = 2e-29
 Identities = 80/211 (37%), Positives = 125/211 (59%), Gaps = 12/211 (5%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN    IP + LGT +         D   +AV  A+  GYR ID A +Y +E +VG+ +A
Sbjct: 14  LNTKAKIPAIGLGTWQSGG------DLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALA 67

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI------ 439
           EA  NG + RE++F+T+KL+   ++ +++  +++ SLK LG+ Y+DLYL+H+P       
Sbjct: 68  EAF-NGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGD 126

Query: 440 ATKPDDSP--DNIDYL----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 601
           AT P  +   D+  +L    + W+ M+   +LGL R+IGVSNF   QI  L+  + I P 
Sbjct: 127 ATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPA 186

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +NQ++++P   Q+ LV  CQS GI V A++P
Sbjct: 187 VNQVKLHPFWRQDELVKFCQSKGIHVSAHTP 217


>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
           Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
           - Neurospora crassa
          Length = 322

 Score =  130 bits (315), Expect = 2e-29
 Identities = 82/214 (38%), Positives = 116/214 (54%), Gaps = 11/214 (5%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQ----AVYWAIEAGYRHIDTAAVYQDE 253
           P ++L+DGN IP++  G G    K  DS D + +    A   A+ AGY H+D A VY +E
Sbjct: 25  PSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGNE 84

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
            ++G+    AIA   + R  L++TTK      A D V  +   SL+KLGLDY+DLYL+H 
Sbjct: 85  VELGR----AIAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHS 138

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV---SNSYIRPVI 604
           P   K   +P+ +     W+ M+  +  G+A+SIGVSNF  + +  L          PV+
Sbjct: 139 PFFAK---NPEQLQ--AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPPVV 193

Query: 605 NQIEVNP----TNTQEPLVAHCQSLGIAVMAYSP 694
           NQIE +P        E LVA C+   IA+ AYSP
Sbjct: 194 NQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSP 227


>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
           Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 282

 Score =  130 bits (315), Expect = 2e-29
 Identities = 79/205 (38%), Positives = 122/205 (59%), Gaps = 5/205 (2%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L++G  IP +ALGT      ++  I      VY  ++ GYRH DTA +Y +E++VG GI
Sbjct: 7   KLSNGFKIPSIALGTYDIPRSQTAEI------VYEGVKCGYRHFDTAVLYGNEKEVGDGI 60

Query: 275 AEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKL-GLDYIDLYLIHFPIAT 445
            + +    G   REE+F TTKLWN ++   +   A+++ L ++ GL YIDL LIH P+  
Sbjct: 61  IKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-- 118

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEV 619
             + S      LETW+ MQ+A   GL +SIGVSN+    I  L++   +  +PV+NQIE+
Sbjct: 119 --EGSKLR---LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEI 173

Query: 620 NPTNTQEPLVAHCQSLGIAVMAYSP 694
           +P   ++ L  +C+S G+ V A++P
Sbjct: 174 SPWIMRQELADYCKSKGLVVEAFAP 198


>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
           reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to aldo-keto reductase - Nasonia vitripennis
          Length = 353

 Score =  130 bits (314), Expect = 3e-29
 Identities = 87/240 (36%), Positives = 136/240 (56%), Gaps = 17/240 (7%)
 Frame = +2

Query: 26  SLLRIITLTCL-LNAAMAVQAPCI-QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYW 199
           S + + TL C+ ++ +  V+A  + +L+ G+  PIV LGT  G  +     D +   +  
Sbjct: 7   SFVLLATLCCVSISYSQNVEAGTVYRLSSGHNFPIVGLGT-HGLNE-----DVLETVLTG 60

Query: 200 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPAL 376
           A+E G  HIDT+ VY++EE +G+ + +  A G   RE++FVT+KL + D H  + V   +
Sbjct: 61  ALEKGIGHIDTSFVYKNEETIGKVLKDWFAKG-GKREDIFVTSKLPYYDNHP-ESVEKYI 118

Query: 377 QESLKKLGLDYIDLYLIHFP-----------IATKPDDS---PDNIDYLETWQGMQDARQ 514
           + SL+KLGL Y+D+YLIH P           +AT  D S       D +  W+ M+   +
Sbjct: 119 KLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVK 178

Query: 515 LGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            G  +SIG+SNFN TQIT ++  + I+P   Q+EV+  + Q+PL+  CQ  GI V  Y+P
Sbjct: 179 EGRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAP 238


>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
           Ascomycota|Rep: Aldo/keto reductase family proteins -
           Aspergillus oryzae
          Length = 323

 Score =  130 bits (314), Expect = 3e-29
 Identities = 81/213 (38%), Positives = 115/213 (53%), Gaps = 13/213 (6%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN G  IP + LGT      E      V  AV  A+ AGYRHID AA YQ+E +VG G 
Sbjct: 8   KLNSGYNIPAIGLGTWLSKPHE------VENAVEAALRAGYRHIDAAACYQNENEVGNGW 61

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 445
            ++   G V R+++F+T+KLWN  H  + V  A+ ++LK L  DY+DLYLIH+P+A   T
Sbjct: 62  KKS---G-VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHT 117

Query: 446 KPDDSP----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 595
               +P           N+   +TW  ++   +    RSIG+SNF   +I  L+  + I 
Sbjct: 118 NETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIP 177

Query: 596 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           P +NQIE +P   Q  L  + +   I  +AYSP
Sbjct: 178 PAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSP 210


>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
           A - Escherichia coli (strain UTI89 / UPEC)
          Length = 294

 Score =  130 bits (313), Expect = 4e-29
 Identities = 71/186 (38%), Positives = 107/186 (57%), Gaps = 1/186 (0%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G G  + +D  D  +Q+V  AI  GYR IDTAAVY +E+ VG+ + EAI+ GL TREELF
Sbjct: 21  GFGVFQVTDK-DVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELF 79

Query: 320 VTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 496
           +T+KLW  D   +D     ++ SLKK GL+Y DLYL+H  +           DY   W+ 
Sbjct: 80  ITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRA 129

Query: 497 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIA 676
           ++DA + G  ++IGVSNF    +        ++P++NQ+E++P   Q   +A  +   + 
Sbjct: 130 LEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQ 189

Query: 677 VMAYSP 694
             A++P
Sbjct: 190 PEAWAP 195


>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
           Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
           aldo-keto reductase/oxidase - Rhizobium leguminosarum
           bv. viciae (strain 3841)
          Length = 274

 Score =  130 bits (313), Expect = 4e-29
 Identities = 76/177 (42%), Positives = 106/177 (59%), Gaps = 1/177 (0%)
 Frame = +2

Query: 167 SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDK 346
           S DE  Q V WA+EAG RHIDTA  Y +E+ V +GI +A   G V R E+F+TTK+  D 
Sbjct: 21  SADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIKDA---G-VARNEIFITTKVKPDN 76

Query: 347 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLA 526
           +    V+P+++ESL+KL +D +DL L+H+P    P +     DYL  +  + D+   GLA
Sbjct: 77  YGPGAVMPSVRESLEKLRVDQVDLLLLHWP---SPHNKYPLADYLGQFAEVFDS---GLA 130

Query: 527 RSIGVSNFNATQITRLVSNSYIRPV-INQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           R IGVSNF    I   +     R +  NQ+E +      P++ +CQ+LGIAV AYSP
Sbjct: 131 RQIGVSNFTKAMIDESIRLLDSRTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSP 187


>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 700

 Score =  130 bits (313), Expect = 4e-29
 Identities = 81/203 (39%), Positives = 118/203 (58%), Gaps = 17/203 (8%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G GT K S   ++   AV  AI+ GYRHID A  Y++E+ V  GI +A   G V R +L+
Sbjct: 24  GFGTWKMSK--EQATPAVAHAIKTGYRHIDCAWAYRNEDAVAAGIKKA---G-VPRSQLW 77

Query: 320 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----------------TKP 451
           +T+KLWN  H  + V  AL  SLK LG DY+DLYL+H+P+A                  P
Sbjct: 78  LTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHP 137

Query: 452 DDSPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT 628
            +S D + D++ T++ M++  + G  R+IGVSNFN  + + +V  + I+PV+NQ+EVN  
Sbjct: 138 VESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLG 197

Query: 629 NTQEPLVAHCQSLGIAVMAYSPF 697
              E L  +  + G+ + AYSPF
Sbjct: 198 VHNEELRNYAHAHGVTLQAYSPF 220


>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
           n=1; Rhodobacterales bacterium HTCC2150|Rep:
           2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
           bacterium HTCC2150
          Length = 334

 Score =  129 bits (312), Expect = 6e-29
 Identities = 82/214 (38%), Positives = 113/214 (52%), Gaps = 7/214 (3%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M   A    LN   TIP V  GT         S D+ +  +  AI+AGYRHIDTA+ YQ+
Sbjct: 33  MTNTATTFTLNTTTTIPAVGFGT------YLISNDDAKSTISAAIQAGYRHIDTASGYQN 86

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA-------RDQVVPALQESLKKLGLDY 409
           E+ VG GI   + +  +TR++LFVT KLW    A       + Q +     SL +LGLDY
Sbjct: 87  EKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDY 146

Query: 410 IDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
           +DLYLIH P              LE W+ + + +  G ARSIGVSNFN + +  + +   
Sbjct: 147 VDLYLIHAPYGGDM--------RLEQWRALLELQANGKARSIGVSNFNESHLNEIKAAGL 198

Query: 590 IRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
             P  NQIE++P + +  L+A+     IA +AYS
Sbjct: 199 PMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYS 232


>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Corynebacterium sp. (strain SHS752001)
          Length = 277

 Score =  129 bits (311), Expect = 7e-29
 Identities = 79/203 (38%), Positives = 113/203 (55%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I LNDG       LGT           DE   A+  AI++GYR +DTA  Y++E +VG
Sbjct: 5   PTISLNDGRPFAEPGLGTYNLRG------DEGVAAMVAAIDSGYRLLDTAVNYENESEVG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           +    A+    V R+EL V +K+   +H R + V +++ SL +LGLD IDL LIH+P   
Sbjct: 59  R----AVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP--- 111

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
               +P    +L+TW+GM DAR+ GL RSIGVSNF    +  L+  + + P +NQ+E++P
Sbjct: 112 ----NPSVGRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHP 167

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  L A     GI   ++SP
Sbjct: 168 YFPQAALRAFHDEHGIRTESWSP 190


>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Acinetobacter sp. (strain ADP1)
          Length = 297

 Score =  128 bits (310), Expect = 1e-28
 Identities = 79/203 (38%), Positives = 120/203 (59%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + L+DG++IP  ALG G  T K    +D + +A    +  GYR +D+A  Y++E  VG
Sbjct: 23  PDLILHDGHSIP--ALGFGTYTLKGQQGVDTMLRA----LGHGYRMLDSAFNYENEGAVG 76

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
             + ++   GL+ R+E+F+T+KL    HA D+ +  ++ESL ++  DY+DLYLIH+P   
Sbjct: 77  AAVRQS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP--- 129

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
               +P    Y+E WQ + DA++ G  RSIGVSNF    I  L   + + PVINQ+E++P
Sbjct: 130 ----NPQQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVELHP 185

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q    A+ +S  I  MA+SP
Sbjct: 186 YFNQAEQRAYDESQQIITMAWSP 208


>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
           reductase - Lactobacillus reuteri F275
          Length = 300

 Score =  128 bits (310), Expect = 1e-28
 Identities = 78/204 (38%), Positives = 118/204 (57%), Gaps = 1/204 (0%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P I+LN+G+ IP + LG  +       S+ E +Q V  AI   Y  IDTA  Y +E  VG
Sbjct: 11  PKIKLNNGHLIPQLGLGVWKA------SLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVG 64

Query: 266 QGIAEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           QGI +        R+ +F+TTK++N D+   D++  A+ E LKKL  +Y+DL L+H+P+ 
Sbjct: 65  QGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVN 124

Query: 443 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 622
            K         Y E+W+ ++D  + G A++IGV NFN  ++T L+ ++ I+P INQIE N
Sbjct: 125 DK---------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFN 175

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P   Q  +V  C+   I + A+SP
Sbjct: 176 PLIHQPKIVKFCRENDIQLEAWSP 199


>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
           Saccharomycetales|Rep: D-arabinose dehydrogenase -
           Pichia stipitis (Yeast)
          Length = 326

 Score =  128 bits (309), Expect = 1e-28
 Identities = 78/220 (35%), Positives = 122/220 (55%), Gaps = 21/220 (9%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L++G TIP + LGT        +   E+++ V  A++AGYRHIDTA  Y  EE +GQ + 
Sbjct: 12  LSNGKTIPALGLGT-----VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALK 66

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----- 442
           +    G+V RE+LF+TTK+W       +   +L +SL  LGLDY+DL+L H+P+      
Sbjct: 67  QLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGDE 124

Query: 443 ----TKP---------DDSP-DNIDYLETWQGMQDAR-QLGLARSIGVSNFNATQITRLV 577
                +P         DD P   I Y++ +  ++D        +SIGVSN++  ++ +L+
Sbjct: 125 NGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLL 184

Query: 578 SN-SYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +     +PV+NQIE +P   Q+ LV +C   G+ + AYSP
Sbjct: 185 AAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSP 224


>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Pseudoalteromonas atlantica (strain T6c / BAA-1087)
          Length = 273

 Score =  128 bits (308), Expect = 2e-28
 Identities = 71/175 (40%), Positives = 107/175 (61%), Gaps = 1/175 (0%)
 Frame = +2

Query: 173 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 352
           D+ + AV  A++ GYRHIDTA  Y++E +VG    +AI+   ++R ELFVTTK+W D  +
Sbjct: 24  DDAKLAVENALDVGYRHIDTAQAYENEAEVG----DAISASKISRGELFVTTKVWFDNLS 79

Query: 353 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 532
            D+ + ++Q SL +L  DY+DL L+H+P    PD+     +YL+    ++  ++ GL R 
Sbjct: 80  ADKFITSVQNSLTQLNTDYVDLLLVHWP---SPDNKVSMAEYLKE---LKACKERGLTRH 133

Query: 533 IGVSNFNATQITRLVSNSYIRPVI-NQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IGVSNF  +Q+   +S      ++ NQIEV+P    + LVA+CQ   I V AY P
Sbjct: 134 IGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMP 188


>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
           family protein; n=1; Tetrahymena thermophila SB210|Rep:
           oxidoreductase, aldo/keto reductase family protein -
           Tetrahymena thermophila SB210
          Length = 323

 Score =  127 bits (307), Expect = 2e-28
 Identities = 73/206 (35%), Positives = 118/206 (57%), Gaps = 5/206 (2%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           +QLN+G  +P++ LGT         +++E+   +  A++ GYR+ DTA  Y++E ++GQ 
Sbjct: 15  VQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQA 74

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF---PIA 442
                  G   RE++F+TTKL+  K  + ++   +Q SL +L   YIDLYLI +   P+ 
Sbjct: 75  FQNIFQQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQWSFTPVL 133

Query: 443 TKPDDSP--DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
           T  D S   ++    E W+ +++  +LG+ RSIGV+NFN   +  L+S + I+PV+NQIE
Sbjct: 134 TNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
           V P   Q  L+   +   I  +A SP
Sbjct: 194 VTPYLPQIDLINFLKRCKIETVAISP 219


>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
           eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 176

 Score =  127 bits (306), Expect = 3e-28
 Identities = 69/162 (42%), Positives = 102/162 (62%), Gaps = 10/162 (6%)
 Frame = +2

Query: 110 NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA 289
           +++P++  GT      E   + E    V  AI+ GYRH DT+  YQ EE +G+ +AEA++
Sbjct: 19  HSMPVLGFGTAASPLPEPTMLKET---VIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVS 75

Query: 290 NGLV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP---- 451
            GLV +R E FVTTKLW  D H    VVPA++ SLK L LDY+DLY+IH+P+++KP    
Sbjct: 76  LGLVRSRSEFFVTTKLWCADAHG-GLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYK 134

Query: 452 ----DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 565
               +D    +D+   W  M++ ++LGLA+ IGVSNF+  ++
Sbjct: 135 FPIDEDDFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176


>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
           discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
           discoideum AX4
          Length = 305

 Score =  127 bits (306), Expect = 3e-28
 Identities = 77/209 (36%), Positives = 121/209 (57%), Gaps = 10/209 (4%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I LN+ N  PI     G GT K    ++++   +   +E GYR IDTA++Y +EE++G+ 
Sbjct: 15  IILNELNLNPIKMPMLGIGTFK----LNDIENIIKVGLENGYRRIDTASMYNNEERIGKV 70

Query: 272 IAEAIA--NGL----VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
           + E +   +GL    + RE+LF+T+K    +   +  + A + SLKKL LDY+D YLIH+
Sbjct: 71  LNEMVTKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHW 130

Query: 434 PIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS--NSYIRPV 601
           P     D  DS ++I   +TW+ ++   Q    RSIGVSN+    +T L+S  N  I+P 
Sbjct: 131 PGVKGLDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPA 190

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAY 688
           INQ+E +P N Q+ L+  C++  I + +Y
Sbjct: 191 INQVEFHPLNFQKDLLEFCKNNKIILESY 219


>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein T08H10.1 - Caenorhabditis elegans
          Length = 333

 Score =  126 bits (305), Expect = 4e-28
 Identities = 75/213 (35%), Positives = 121/213 (56%), Gaps = 12/213 (5%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I LN G  +P+  LGT +   K+     E+  A+  A++AGYR IDTA +YQ+E  +G+ 
Sbjct: 6   IPLNTGAQLPLFGLGTWQ--VKDEA---ELTVALRAALDAGYRLIDTAHLYQNEHIIGKV 60

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + E I++G + RE++FVT+KL    HA + V   ++  LK L L+YIDLYLIH P   K 
Sbjct: 61  LHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKH 120

Query: 452 DD------------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 595
            +            +   I +++TW+ ++   + G  +++GVSNF+  Q+  L   + ++
Sbjct: 121 QEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVK 180

Query: 596 PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           P   Q+E +    Q+ L A C+ LG+ V AY+P
Sbjct: 181 PANQQVECHIYWPQQELRALCKKLGVTVTAYAP 213


>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
           Lin2349 protein - Listeria innocua
          Length = 294

 Score =  126 bits (303), Expect = 7e-28
 Identities = 78/197 (39%), Positives = 112/197 (56%), Gaps = 1/197 (0%)
 Frame = +2

Query: 107 GN-TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 283
           GN TIP + LG  + T +E      +  AV  AIE GYR  DTAAVY +E  VGQ    A
Sbjct: 13  GNETIPYIGLGVFQVTEQEF-----IAGAVEKAIEVGYRLFDTAAVYNNEAIVGQ----A 63

Query: 284 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 463
           I +  V REELF+++K+WN     D+ + A + +L+ L LDY+DLYLIH+P+A K     
Sbjct: 64  ILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK----- 118

Query: 464 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP 643
               Y ++W+ M+      L +SIGV+NF    ++ L+  +  +PV+NQ+E +P   Q  
Sbjct: 119 ----YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQND 174

Query: 644 LVAHCQSLGIAVMAYSP 694
           L  +     IA  A+SP
Sbjct: 175 LRKYLAEQNIAHAAWSP 191


>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
           Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
           Oceanobacillus iheyensis
          Length = 280

 Score =  126 bits (303), Expect = 7e-28
 Identities = 84/208 (40%), Positives = 112/208 (53%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M  Q P + L+DG TIP V  GT R     +D +    QA+  AI+ GYR IDTA  Y++
Sbjct: 1   MVNQIPNVTLHDGLTIPKVGFGTYR--LNGNDGV----QAINNAIDHGYRLIDTAYNYEN 54

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E  VG    EA+      RE+L +T+KL    H  D+ V  +QESL +  LDY DLYLIH
Sbjct: 55  EGTVG----EAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIH 110

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
           +P       +P    Y+E WQ + +A++ G  RSIGV NF    + RL   +   P INQ
Sbjct: 111 WP-------NPIQDIYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQ 163

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IE++P   QE      Q   IA  ++SP
Sbjct: 164 IELHPFFNQEDQRKWHQEHQIATESWSP 191


>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 288

 Score =  126 bits (303), Expect = 7e-28
 Identities = 79/205 (38%), Positives = 108/205 (52%)
 Frame = +2

Query: 80  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 259
           + P I LNDG  IP +    G GT +  D      QAV  A+  GYRHIDTA  Y +E++
Sbjct: 3   KTPTITLNDGRAIPAI----GFGTFQIPDD-GSTYQAVKEALVIGYRHIDTAVAYFNEDE 57

Query: 260 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
           VGQ    AI +  + R++++VT+KLW   +  D    A+  SL KL LDYIDLYLIH P 
Sbjct: 58  VGQ----AIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPY 113

Query: 440 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
              P            WQ M+ A++ G  +SIGVSN   T   + V      P +NQ+E 
Sbjct: 114 GDVPG----------AWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVEF 163

Query: 620 NPTNTQEPLVAHCQSLGIAVMAYSP 694
           NP   Q+PL     +  + + A++P
Sbjct: 164 NPYFQQQPLRQLLAAQDVKLEAWAP 188


>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
           ATCC 50803
          Length = 313

 Score =  126 bits (303), Expect = 7e-28
 Identities = 65/189 (34%), Positives = 109/189 (57%), Gaps = 15/189 (7%)
 Frame = +2

Query: 173 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI--ANGLVTREELFVTTKLWNDK 346
           + V+ AV  A+  GYRHID A VYQ+EE +G+   +    A+  + RE++++T+KLWN  
Sbjct: 17  EAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYN 76

Query: 347 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD-------------NIDYLET 487
           H  + V    ++++  L +DY+DL+L+H+P+A   +D  D              +   +T
Sbjct: 77  HRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADT 136

Query: 488 WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSL 667
           W+ M+   + GL + IGVSN+    +  L++ + I+P++NQIE++P +  +  V  C   
Sbjct: 137 WRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDN 196

Query: 668 GIAVMAYSP 694
           GI V AYSP
Sbjct: 197 GIGVTAYSP 205


>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
           Oxidoreductase - Lactobacillus plantarum
          Length = 282

 Score =  125 bits (302), Expect = 9e-28
 Identities = 79/208 (37%), Positives = 110/208 (52%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M V     QL +G  IP VA GT +    E+       QAV  A+ AGYRHIDTA  YQ+
Sbjct: 1   MTVLTTMYQLANGVNIPKVAFGTWQIPGGEA-----TYQAVRAALAAGYRHIDTALAYQN 55

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E  VGQ    AI +  + RE++FVTTKL  +  +    +     SLK LGLDY+DLYL+H
Sbjct: 56  EASVGQ----AIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVH 111

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
            P          +   L+ WQ M+   Q G A++IGVSNF    +  +++ + I P++NQ
Sbjct: 112 APWPWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQ 171

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           I+     T+  +    +   + V AYSP
Sbjct: 172 IQYYLGFTEPKITKFSEEHAMLVEAYSP 199


>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
           n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
           Apis mellifera
          Length = 292

 Score =  125 bits (301), Expect = 1e-27
 Identities = 72/202 (35%), Positives = 112/202 (55%), Gaps = 4/202 (1%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L+ G  +P++  GT +   +E      V Q V  ++  G+R IDTA  Y++EE +G  + 
Sbjct: 10  LSSGYDMPLIGFGTYKIQGREL-----VYQVVDESLNVGFRSIDTAVGYRNEEDIGYALK 64

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQ-VVPALQESLKKLGLDYIDLYLIHFPIATK-P 451
             +    + R ++F+TTKL    +   + +   +Q+SLK     YIDLYLIH+P AT+ P
Sbjct: 65  NLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIP 124

Query: 452 DDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYIRPVINQIEVNP 625
           + S +N     +TW  + D ++ G  RSIGVSNF    +  L+ N   I P +NQ+E++P
Sbjct: 125 ETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHP 184

Query: 626 TNTQEPLVAHCQSLGIAVMAYS 691
              QE L+ +C   GI + AYS
Sbjct: 185 HYRQEELIKYCNEKGIHIQAYS 206


>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
           n=1; Rhodococcus sp. RHA1|Rep: Probable
           2,5-didehydrogluconate reductase - Rhodococcus sp.
           (strain RHA1)
          Length = 265

 Score =  125 bits (301), Expect = 1e-27
 Identities = 70/173 (40%), Positives = 103/173 (59%)
 Frame = +2

Query: 176 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 355
           +  +AV   IEAGYR IDTA +Y +E+ VG  +AE    G V REELFVTTKL    H  
Sbjct: 18  DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC---G-VPREELFVTTKLRGSDHVS 73

Query: 356 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 535
             +  A++ SLK LGLD +DL+LIH+P+       P +  Y+  ++ M   R  GL R +
Sbjct: 74  GDIRGAVERSLKNLGLDRLDLFLIHWPL-------PRHNRYVAAFEAMLACRDAGLVRHV 126

Query: 536 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           GVSNF  T + R+V+ +   P +NQI+++P+  + P+      LG++  ++SP
Sbjct: 127 GVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLPVRRADDELGVSTQSWSP 179


>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
           bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
           bacterium HTCC2654
          Length = 278

 Score =  124 bits (300), Expect = 2e-27
 Identities = 80/204 (39%), Positives = 118/204 (57%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           AP + L +G  +P + LGT   T       DE  +AV  AIE GYR IDTA  Y++E  V
Sbjct: 7   APTVTLANGVEMPQLGLGTWPMTD------DEAAKAVATAIETGYRLIDTAENYKNETGV 60

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 442
           GQGI +A   G V R+E+F+TTK+    H+ D    A + SL++LGLDYIDL+LIH+P  
Sbjct: 61  GQGIRDA---G-VARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP-- 114

Query: 443 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 622
                +PD   Y+E ++G+      GL R+IG SNF    +  L +  ++ P +NQI+++
Sbjct: 115 -----NPDQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQLD 168

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P + +  + A   + GI   ++SP
Sbjct: 169 PYHLRPDITAIHAAKGIVTESWSP 192


>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 339

 Score =  124 bits (300), Expect = 2e-27
 Identities = 84/225 (37%), Positives = 117/225 (52%), Gaps = 17/225 (7%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA   P   LN G  +P V +G  +G        +E+  A+  AI+ GYRH+DTA  Y++
Sbjct: 1   MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRD-NELVDALVRAIKVGYRHLDTATGYRN 59

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E +VGQ    A+    V R E+FVTTKL       D VV  L+ SL +LG+DYIDL+L+H
Sbjct: 60  EAEVGQ----AVRQSGVARSEIFVTTKL-RPGGVHD-VVQELENSLNELGIDYIDLWLLH 113

Query: 431 FPIATKPDDSP---------DNIDYL-----ETWQGMQDA---RQLGLARSIGVSNFNAT 559
           +P     DD           ++  +L     ETW  M+D       G  ++IGVSNF+  
Sbjct: 114 WPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIK 173

Query: 560 QITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +  L   S + P +NQIE +P   +  LV +C+   I V AYSP
Sbjct: 174 NLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSP 218


>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
           Propionibacterium freudenreichii subsp. shermanii|Rep:
           Putative aldo-keto reductase - Propionibacterium
           freudenreichii subsp. shermanii
          Length = 280

 Score =  124 bits (299), Expect = 2e-27
 Identities = 73/203 (35%), Positives = 118/203 (58%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P ++L+ G  +P++ +GT           +E R AV  AIE GYR +DTA  Y +EE VG
Sbjct: 9   PTVELSGGTRMPMLGMGTWPLKG------EECRAAVASAIEQGYRLVDTAEAYGNEEAVG 62

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
           + + EA  +    R E+FVTTK     H+R  V  AL+ SL++LGLDY+DL+L+H+P+  
Sbjct: 63  KAVREAGPD----RAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM-- 116

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
                P    Y++ ++GM + ++ GLA++IGVSNF    +  L++   + P +NQI+++P
Sbjct: 117 -----PGEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQIQLDP 170

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
           +  +  +     +  I   A+SP
Sbjct: 171 SRPRLEVRDFLDNHDIVTEAWSP 193


>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
           protein; n=9; Trichomonas vaginalis G3|Rep:
           Oxidoreductase, aldo/keto reductase family protein -
           Trichomonas vaginalis G3
          Length = 308

 Score =  124 bits (299), Expect = 2e-27
 Identities = 77/210 (36%), Positives = 110/210 (52%), Gaps = 16/210 (7%)
 Frame = +2

Query: 110 NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA 289
           N IP + LGT +    E    D V    Y   EAGY HID A  Y++E+ VGQ + +   
Sbjct: 2   NRIPTIGLGTWKSPRSE----DLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWD 57

Query: 290 NGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--------- 442
           +G + RE +++T+KLWN  H  + V  A +++LK L LDY+DLYL+H+P A         
Sbjct: 58  SG-IKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGS 116

Query: 443 TKPDDS------PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL-VSNSYIRPV 601
             P D        D +  ++TW+ M+   + GL + IGVSN+   Q+ RL  S++   P 
Sbjct: 117 LNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPY 176

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
            NQ+E N    Q PL  +    GI V  YS
Sbjct: 177 TNQVEFNLYMQQGPLREYMHKEGIIVTGYS 206


>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
           Aldehyde reductase - Lactobacillus acidophilus
          Length = 278

 Score =  124 bits (298), Expect = 3e-27
 Identities = 70/202 (34%), Positives = 113/202 (55%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN+G  +P +  G       + D + + +Q V   +E GYR +DTA +Y +E+ VG  
Sbjct: 5   VTLNNGIKMPRLGFGV-----YQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG-- 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
             +AI +  V RE++F+T+K+W D +  D  + A  +S+KKL LDYIDLYLIH P     
Sbjct: 58  --DAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN--- 112

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                  DY  TW+ ++   Q G  R+IGVS+F   ++  L++ + ++P +NQIE N  N
Sbjct: 113 -------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWN 165

Query: 632 TQEPLVAHCQSLGIAVMAYSPF 697
            +     + +  G+   A++PF
Sbjct: 166 QEWKSQQYMEKEGVQPEAWAPF 187


>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
           Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
           Lactobacillus acidophilus
          Length = 271

 Score =  123 bits (297), Expect = 4e-27
 Identities = 79/202 (39%), Positives = 107/202 (52%), Gaps = 3/202 (1%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IP + LGT         + DEV + V  A+  GYR  DTA  Y +E  VG+GI 
Sbjct: 9   LNNGEKIPQIQLGTWL------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIW 62

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP---IATK 448
               N  + R ++F+TTKL       +    A+  +L K GL+YIDL LIH P   I   
Sbjct: 63  ----NSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVN 118

Query: 449 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT 628
             +       LE W+ M++A + G  RSIGVSNF    I  +V+N  I P +NQIEV+  
Sbjct: 119 RTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIG 178

Query: 629 NTQEPLVAHCQSLGIAVMAYSP 694
                L+ +C+ LGI + AYSP
Sbjct: 179 KVPVELMDYCKKLGIKIEAYSP 200


>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
           Klebsiella pneumoniae|Rep: Putative uncharacterized
           protein - Klebsiella pneumoniae
          Length = 279

 Score =  123 bits (297), Expect = 4e-27
 Identities = 74/202 (36%), Positives = 118/202 (58%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I LNDG  +P    G      ++ DS+  +RQA    ++AG+RH DTA  Y +E+ VG+ 
Sbjct: 6   ILLNDGYYMPRPGCGLWLIDNRDVDSL--IRQA----LKAGFRHFDTAQAYFNEDGVGR- 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
              A+    V RE+LF+T+K+        + + +  E+L++LG++Y++L+LIH+PI  K 
Sbjct: 59  ---ALRYTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAK- 114

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                N+ Y+ETW+   +    GL RSIGVSNF    I RL+ ++ + P +NQ+E++P  
Sbjct: 115 -----NL-YVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHF 168

Query: 632 TQEPLVAHCQSLGIAVMAYSPF 697
            Q  +  +    GIA+ +YSPF
Sbjct: 169 QQCDVRDYHHEAGIAIQSYSPF 190


>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
           Lin2848 protein - Listeria innocua
          Length = 280

 Score =  123 bits (296), Expect = 5e-27
 Identities = 74/200 (37%), Positives = 117/200 (58%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN+G  +P      G G  K +D    +R A+  A++ GYR  DTA+ Y +E+++G   
Sbjct: 10  RLNNGIEMP----RHGFGVYKLTDE-QRMRTALETAVDVGYRLFDTASFYHNEKELGDFF 64

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
           A   ++GL  R+E FVTTK+WN +   D+ + A ++S KKL LD +DLYL+H+P   K D
Sbjct: 65  A---SSGL-KRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD 117

Query: 455 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 634
                  + ETW+ ++     GL R+IGVSNF A  + RL +++ + PV++Q+E +P   
Sbjct: 118 ------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFP 171

Query: 635 QEPLVAHCQSLGIAVMAYSP 694
            + L  + + L I   A+SP
Sbjct: 172 NQLLHRYLEELHIVHQAWSP 191


>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Staphylococcus|Rep: Oxidoreductase,
           aldo/keto reductase family - Staphylococcus epidermidis
           (strain ATCC 35984 / RP62A)
          Length = 279

 Score =  123 bits (296), Expect = 5e-27
 Identities = 71/199 (35%), Positives = 113/199 (56%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  +P V LG      K +D  +++ + V  A++AGYR  DTA  Y +E+ +G    
Sbjct: 8   LNNGYPMPAVGLGV----YKIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS--- 58

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
            A+ +  V R+ELF+T+KLWND    DQ +    +SL  LGLDY+DL+LIH+P       
Sbjct: 59  -ALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCEN---- 113

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 637
             D + Y+E+++ ++   + G  ++IGV NF    + +L+  + I P +NQIE++P   Q
Sbjct: 114 --DQL-YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQ 170

Query: 638 EPLVAHCQSLGIAVMAYSP 694
           + +   C    I V A+ P
Sbjct: 171 QDVQDFCDEHDIKVTAWMP 189


>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
           Parabacteroides merdae ATCC 43184|Rep: Putative
           uncharacterized protein - Parabacteroides merdae ATCC
           43184
          Length = 301

 Score =  123 bits (296), Expect = 5e-27
 Identities = 82/211 (38%), Positives = 114/211 (54%)
 Frame = +2

Query: 62  NAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAV 241
           NA    + P ++LN+G  +P   LG G    K     D   + V  AI+ G+R IDTA  
Sbjct: 22  NAQEMNKVPTVKLNNGMEMP--QLGVGTFLVK-----DNAAERVCHAIKVGFRLIDTAQG 74

Query: 242 YQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLY 421
           Y +E++VG+GI  +   G + R ELF+TTK+   +     V  +L +SL  LG DYIDL 
Sbjct: 75  YGNEKEVGEGICRS---G-IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLV 130

Query: 422 LIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 601
           LIH+P+              ETWQ +++    G  RSIGVSNFN   +  L+  + IRPV
Sbjct: 131 LIHWPVKGH---------IKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPV 181

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +NQIE+ P  TQ  +V +    GI V A+ P
Sbjct: 182 VNQIEIEPYMTQHDVVGYTFRKGIQVEAWGP 212


>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
           Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
           sp. (strain FB24)
          Length = 287

 Score =  123 bits (296), Expect = 5e-27
 Identities = 76/208 (36%), Positives = 120/208 (57%), Gaps = 1/208 (0%)
 Frame = +2

Query: 74  AVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDE 253
           A   P ++L  G+TIP + LGT           DE   AV +A+++GYR +DTA  Y++E
Sbjct: 10  ASDIPRLKLPHGHTIPRLGLGTWPMLE------DECETAVRFALQSGYRLVDTAFQYRNE 63

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
           E VG+GI  A   G V R ELF+++K   + H+ D V  A  ESL+KLGLD++D+++ H+
Sbjct: 64  EAVGRGIRTA---G-VPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW 119

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
           P+       P    Y++ W+G+    + G  ++IGVSNF    +  ++  + + P +NQI
Sbjct: 120 PV-------PALGKYVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172

Query: 614 EVNPTNTQ-EPLVAHCQSLGIAVMAYSP 694
           +++P   + EP   H + LGI   A+SP
Sbjct: 173 QLSPDLARTEPRAVH-RLLGIVTEAWSP 199


>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
           reductase; n=1; Gluconobacter oxydans|Rep: Putative
           2,5-diketo-D-gluconic acid reductase - Gluconobacter
           oxydans (Gluconobacter suboxydans)
          Length = 279

 Score =  122 bits (295), Expect = 6e-27
 Identities = 69/201 (34%), Positives = 111/201 (55%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I  +DG+T+P + LG            DE  + V  A++ GYR +DTA +Y++EE VG+G
Sbjct: 14  ISFHDGHTMPQIGLGVWETPP------DETAEVVKEAVKLGYRSVDTARLYKNEEGVGKG 67

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + +          E+F+TTKLWND+   D  + A +ES + L    +DLYLIH+P+    
Sbjct: 68  LED--------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPM---- 115

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
              P    Y+ETW+ + + ++ G  +SIGVSNF +  + R++  + + PV+NQIE++P  
Sbjct: 116 ---PAQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELHPDF 172

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  L    +   I   ++ P
Sbjct: 173 QQRALREFHEKHNIRTESWRP 193


>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Lactobacillus brevis ATCC
           367|Rep: Aldo/keto reductase of diketogulonate reductase
           family - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 268

 Score =  122 bits (293), Expect = 1e-26
 Identities = 74/200 (37%), Positives = 113/200 (56%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           QL++G TIP++  GT    +K+      V  A+  A++AGYRH+D A +Y +E  VG+ I
Sbjct: 5   QLSNGVTIPMLGFGTYLIDSKD------VPAAIKTALDAGYRHLDCAHIYGNEPAVGEAI 58

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
               A+G + R +LF+T+K+WN     D+ + A  ++L  L LDY+DLYLIH+P     D
Sbjct: 59  K---ASG-IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NED 111

Query: 455 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 634
           D    +D   TW+ ++   Q    R+IGVSNF+  Q+ ++   + ++P+INQIE +P   
Sbjct: 112 DFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKV 168

Query: 635 QEPLVAHCQSLGIAVMAYSP 694
           Q  L        I    YSP
Sbjct: 169 QADLGQFDTDNDIVNEGYSP 188


>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
           Bacteria|Rep: 2,5-didehydrogluconate reductase -
           Arthrobacter sp. (strain FB24)
          Length = 291

 Score =  122 bits (293), Expect = 1e-26
 Identities = 79/217 (36%), Positives = 116/217 (53%), Gaps = 13/217 (5%)
 Frame = +2

Query: 83  APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 262
           +P + LN+G  + I  LG G      +D+   V  A    +EAGYRH DTAA+Y +E  V
Sbjct: 4   SPRLSLNNG--VLIDQLGFGLYKVPPADAAGLVTMA----LEAGYRHFDTAAMYGNETGV 57

Query: 263 GQGIAE--AIANG-----------LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGL 403
           G+ I      A G            ++RE+LFVTTK+WND H  D  + A   S+  LG+
Sbjct: 58  GKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGM 117

Query: 404 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 583
           +Y+DLYLIH+P A +         + E+++ M+   + G  R+IGVSNF    +  L+  
Sbjct: 118 EYVDLYLIHWPCARRG-------LFTESYRAMETLYREGRIRAIGVSNFQPAHLEHLLET 170

Query: 584 SYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           + + P +NQIE++P   Q+ L      LGI   A+SP
Sbjct: 171 AEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSP 207


>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
           Filobasidiella neoformans|Rep: Aldo-keto reductase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 303

 Score =  121 bits (292), Expect = 1e-26
 Identities = 70/201 (34%), Positives = 109/201 (54%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++++DGN IP   LG      KE+         V WA+EAGYRH+DTA  Y++E   G+ 
Sbjct: 33  LKMHDGNAIPQFGLGVYEMNDKET------YDCVKWALEAGYRHVDTAEWYENEAPCGKA 86

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           IA+ +     +REE+F+T+KL N+  + +Q    L+ SLK+ G++Y DLYL+H  I    
Sbjct: 87  IADFLKATGTSREEIFLTSKLKNNS-SYEQAFVDLKGSLKRSGVEYFDLYLMHSAIG--- 142

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
              P  +     W+ + DA+  GL +SIGVSNF    I   +      P +NQ++++P  
Sbjct: 143 --GP--VIRKNVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFM 198

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
               +V  C+   I + A+ P
Sbjct: 199 RHPEIVEICEQNEILLEAWGP 219


>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 292

 Score =  121 bits (291), Expect = 2e-26
 Identities = 74/211 (35%), Positives = 115/211 (54%)
 Frame = +2

Query: 62  NAAMAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAV 241
           NA  +   P   L  G+ IP++  GT +  A E D+ D V +A    +E GYRHIDTA +
Sbjct: 9   NAPASSPIPTFMLPTGSPIPVLGFGTYK-VAPE-DTYDAVSRA----LEVGYRHIDTAQM 62

Query: 242 YQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLY 421
           Y +E +VG  +    A+G + RE+LF+TTK+ N  H  D+   +++ SL+ L  DY+DL 
Sbjct: 63  YGNEAEVGAALE---ASG-IAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLL 118

Query: 422 LIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 601
           L+H+P+ T         D    W  ++DA   G AR+IG+SN+    +  +   + + P 
Sbjct: 119 LVHWPLPTLYGG-----DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPH 173

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           + Q+E +P      L A+ Q LG+   A+SP
Sbjct: 174 VLQVESHPFFPNADLRAYAQGLGMVFEAWSP 204


>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
           ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 310

 Score =  121 bits (291), Expect = 2e-26
 Identities = 75/204 (36%), Positives = 114/204 (55%), Gaps = 4/204 (1%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L+DG  IP V LG  + + +       V+  VY A+E GYR  D+A  Y +E+ V +GI
Sbjct: 14  RLSDGTQIPSVGLGVYQVSEQT------VQDLVYEALEVGYRLFDSAQAYHNEDGVARGI 67

Query: 275 AEAIANGLVTR-EELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIATK 448
           A  + +    R E+++ TTK+    H  +    +L++SL   G L YIDL L+H P++  
Sbjct: 68  AAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS-- 125

Query: 449 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS--NSYIRPVINQIEVN 622
                D    L TWQ +++A   G  RSIGVSN+    ++ L+      IRPV+NQ+E+N
Sbjct: 126 -----DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEIN 180

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P   ++ LV +C+   IAV A+SP
Sbjct: 181 PWLCRQELVQYCRENNIAVQAFSP 204


>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
           Trichoderma atroviride (Hypocrea atroviridis)
          Length = 327

 Score =  120 bits (290), Expect = 3e-26
 Identities = 75/215 (34%), Positives = 114/215 (53%), Gaps = 16/215 (7%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN G  IP V    G GT     +  E   AV  A++ GYRH+D A  Y +E++VG  I 
Sbjct: 17  LNTGAKIPAV----GFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVGDAIR 72

Query: 278 EAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
           + +A    VTR++LF+ TK+WN  H  + V  + + S + L +DYIDL+L+H+PIA + +
Sbjct: 73  DFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKN 132

Query: 455 D------SPDNIDYLE---------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
                   PD    +          TW+ M++    G+ ++IGVSN+    + +L+  + 
Sbjct: 133 ADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFAR 192

Query: 590 IRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           I+P +NQIE++P      LV  C    I   AYSP
Sbjct: 193 IKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSP 227


>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 355

 Score =  106 bits (255), Expect(2) = 3e-26
 Identities = 67/169 (39%), Positives = 96/169 (56%), Gaps = 13/169 (7%)
 Frame = +2

Query: 227 DTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLD 406
           D A +Y +E +VGQGI    A+G V R ELFVTTK+W   H + +    L ESL++LGLD
Sbjct: 80  DAAWIYGNENEVGQGIK---ASG-VPRSELFVTTKIWCTYHRQPEA--CLDESLQRLGLD 133

Query: 407 YIDLYLIHFPIA-TKPDDS--PDNIDYL----------ETWQGMQDARQLGLARSIGVSN 547
           Y+DL L+H+P+   K  D   P N D            +TW+ M+     G  ++IGVSN
Sbjct: 134 YVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAIGVSN 193

Query: 548 FNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++   + +L++ + I P  NQ+E++P   Q  LV +C   GI   AYSP
Sbjct: 194 WSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSP 242



 Score = 34.7 bits (76), Expect(2) = 3e-26
 Identities = 20/44 (45%), Positives = 26/44 (59%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHI 226
           +LN G  IP++ LGT +          EV +AV  AI+AGYRHI
Sbjct: 15  KLNTGAEIPVIGLGTWQSAP------GEVAKAVESAIKAGYRHI 52


>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
           Aldo-keto reductase - Helicobacter hepaticus
          Length = 292

 Score =  120 bits (288), Expect = 4e-26
 Identities = 77/203 (37%), Positives = 111/203 (54%), Gaps = 4/203 (1%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+GN IP + LGT R      D++  V  AV  A + GYRHIDTA  Y +E    +G+ 
Sbjct: 17  LNNGNKIPKLGLGTWR----IDDNV--VEAAVREAFKVGYRHIDTAQAYGNE----RGVG 66

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
           EA+    + REELF+T+K+  +         ++  SLK + LD+IDL LIH P   +P +
Sbjct: 67  EAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSP---QPWN 123

Query: 458 SPDNIDY----LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
           S    DY    +E +  ++DA++ G  RSIGVSNF    +  ++ N   +P  NQI  + 
Sbjct: 124 SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILCHI 183

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
            NT   L+ +C+   I   AYSP
Sbjct: 184 GNTPFTLLDYCKKQNILAEAYSP 206


>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=2; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
          Length = 273

 Score =  120 bits (288), Expect = 4e-26
 Identities = 75/201 (37%), Positives = 112/201 (55%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN+   IPI   GT         S D+ +QAV  A E GYR IDTA  YQ+E+QVG+ 
Sbjct: 4   LTLNNDVKIPIFGFGT------YEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           +    A+GL  R+E+F+TTK   D +   ++   L ESL+++GLDY DL LIH+P+    
Sbjct: 58  VK---ASGL-NRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD- 110

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                    ++TW  ++ A + G  R+IG+SNFN+ Q   L+  S +RP+++QIE +   
Sbjct: 111 ---------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFL 161

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  +    +   I   +YSP
Sbjct: 162 QQWKMHEFLEKENIVHESYSP 182


>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 286

 Score =  120 bits (288), Expect = 4e-26
 Identities = 81/214 (37%), Positives = 118/214 (55%), Gaps = 6/214 (2%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           MA      +L +G+T+P + LGT +G     D  ++V+  V  AI+AGYRHID AA Y +
Sbjct: 1   MATPTASFRLVNGSTLPAIGLGTFQG----DDGNEKVKNIVKAAIQAGYRHIDGAAAYGN 56

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           EE +G  I E+   G ++R+EL    + W   H    V  AL  SL+ LGL+Y+      
Sbjct: 57  EEAIGDAIKES---G-ISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV------ 100

Query: 431 FPIATKPDDSPDNIDY------LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
            P A  P   P+N+DY       ETWQ M+     G A++IG+SNFN  +  R++  + I
Sbjct: 101 -PHAYLP--GPNNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARI 157

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           RP +NQ+E +P   Q  L+A C+   I +MA+ P
Sbjct: 158 RPAVNQVEAHPYFPQHELLAFCEKEHIHLMAHQP 191


>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG2767-PA - Nasonia vitripennis
          Length = 356

 Score =  119 bits (286), Expect = 8e-26
 Identities = 76/214 (35%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I+L+ G+ +P++ LGT +         + +  AV  A+E+GYRHIDTA  Y +EE +G+ 
Sbjct: 28  IKLSSGHDMPMIGLGTWQMPP------EAIEVAVTAALESGYRHIDTAFTYGNEEAIGKT 81

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + +    G   RE+LF+TTKL       + V   L+ SL+KLGL+Y+++YLIH P A   
Sbjct: 82  LKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVK 140

Query: 452 DD-------SPD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
           D        +PD       + D++  W+ M+   + G  RSIG+SNFN +Q+  +  ++ 
Sbjct: 141 DKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAE 200

Query: 590 IRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
           I+P   QIE+   N Q P+   C    I V A+S
Sbjct: 201 IKPSNLQIELQAYNQQRPMRELCAERNITVTAFS 234


>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
           protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
           family 1 member C-like protein 1 - Homo sapiens (Human)
          Length = 302

 Score =  119 bits (286), Expect = 8e-26
 Identities = 74/205 (36%), Positives = 112/205 (54%), Gaps = 1/205 (0%)
 Frame = +2

Query: 80  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 259
           Q+  ++LNDG  +P++  GT    A +     +  +A   AI+ G+RHID+A +YQ+EE+
Sbjct: 7   QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63

Query: 260 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
           VGQ I E IA+G V REE+F T KLW      + V PAL+ SLKKLG DY+DL++IH P 
Sbjct: 64  VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123

Query: 440 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ-IE 616
           A K        + L      +DA    +  ++ + +    ++         +P  NQ +E
Sbjct: 124 AMKQPGK----ELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVE 174

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYS 691
            +P   Q  L+  C+S  I ++AYS
Sbjct: 175 CHPYLNQSKLLEFCKSKDIVLVAYS 199


>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
           Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
          Length = 308

 Score =  118 bits (284), Expect = 1e-25
 Identities = 69/174 (39%), Positives = 99/174 (56%)
 Frame = +2

Query: 173 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 352
           DE   AV  A+  GYRHIDTAA Y +E +VG+GI  A   G + R+E+F+ TK+W   + 
Sbjct: 42  DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---G-IARDEVFIETKIWISDYG 97

Query: 353 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 532
            D+ + A  +S  KLG+D IDL L+H P+ +  D +      L  ++ ++     G  R+
Sbjct: 98  YDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT------LGAYRALEKLLADGKVRA 151

Query: 533 IGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IGVSNF    +TRL++ + I P +NQIEV+P   Q  L       GI   A+SP
Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWSP 205


>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr1 scaffold_5, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 247

 Score =  118 bits (284), Expect = 1e-25
 Identities = 71/189 (37%), Positives = 107/189 (56%), Gaps = 11/189 (5%)
 Frame = +2

Query: 107 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 286
           G  IP+V + T       S+++ +   ++  AIE GYRH D  A Y  E+ +G+ I +A+
Sbjct: 13  GKAIPLVGMVTTVYPFAPSETMID---SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAV 69

Query: 287 ANGLV-TREELFVTTKLWNDKHARDQVVPALQESLK---------KLGLDYIDLYLIHFP 436
             GL+ +R+ELF+T+KLW      D+V+PALQ +LK          L LDY+DLYLIH+ 
Sbjct: 70  KLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDLYLIHWS 129

Query: 437 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
               P      ID    W+ M+D ++L L ++IGVSNF+  ++  L+  + I P +NQ+ 
Sbjct: 130 DGHLP------IDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEELLQTASILPAVNQVS 183

Query: 617 VN-PTNTQE 640
            N PT   E
Sbjct: 184 ENEPTLAAE 192


>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 264

 Score =  118 bits (284), Expect = 1e-25
 Identities = 72/201 (35%), Positives = 109/201 (54%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LNDG  +P+  LG  R    E+   D       +A++ GYR +DTA +YQ+E++VG  
Sbjct: 13  VTLNDGRKMPLFGLGVFR---LETGCED----VCLFALKNGYRMLDTADIYQNEKEVGSA 65

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           + ++   GL  RE+++VTTKL   +      +   +ES+KKL + Y+DL+LIH P     
Sbjct: 66  VRKS---GL-KREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP----- 116

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
              P NI  +  +  +   ++ GL RS+GVSNF    +  L       P INQIE+NP  
Sbjct: 117 --RPGNI--IAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFW 172

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            QE ++ +C   GI V  Y+P
Sbjct: 173 RQEEIIKYCNKHGITVEGYAP 193


>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 287

 Score =  118 bits (284), Expect = 1e-25
 Identities = 75/206 (36%), Positives = 114/206 (55%), Gaps = 4/206 (1%)
 Frame = +2

Query: 89  CIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 268
           C  L +G+ IP   +G     A ++  I E       A++ GYR IDTA  Y++E + G+
Sbjct: 9   CFPLLNGSRIPACGVGVYLLPASQTAGIVEK------ALDVGYRLIDTAQEYENERETGE 62

Query: 269 GIAEAIANGLVT-REELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIA 442
           GI   +       RE++  TTK+ N     D+   +L+ESL K+  L+YIDL LIH P++
Sbjct: 63  GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS 122

Query: 443 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIE 616
            K          +ETW+ +Q+A   G+ +SIGVSNF    I  L     ++  P++NQIE
Sbjct: 123 DKKTR-------IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++P   ++ LV +CQ+LGI + AY P
Sbjct: 176 LSPWLMRKDLVDYCQNLGIVLEAYCP 201


>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
           Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
           alexandrii HTCC2633
          Length = 275

 Score =  118 bits (283), Expect = 2e-25
 Identities = 68/185 (36%), Positives = 104/185 (56%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G GT +  D  ++  + V  A++ GYRHIDTA +Y +E  VG G  ++   G V RE+ F
Sbjct: 16  GFGTWQLED--EDAARGVATALKTGYRHIDTAQIYGNEAAVGDGWKQS---G-VKREDFF 69

Query: 320 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 499
           +TTK+W DK     +  +++ESL KL  DY+DL L+H+P+   P          ET + M
Sbjct: 70  LTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPVPEVP--------IAETMKAM 121

Query: 500 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAV 679
            + ++ G  R IGVSNF    +    ++S    V NQ+E +P   Q  ++  C++ G+A+
Sbjct: 122 NEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAM 181

Query: 680 MAYSP 694
            AYSP
Sbjct: 182 TAYSP 186


>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
           Phytophthora infestans|Rep: Aldo-keto reductase,
           putative - Phytophthora infestans (Potato late blight
           fungus)
          Length = 255

 Score =  118 bits (283), Expect = 2e-25
 Identities = 69/193 (35%), Positives = 108/193 (55%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+V  P   L  G  IP++ LG       +S+   E   A+  +++ GYRHIDTA +Y +
Sbjct: 1   MSVNVPTKILPSGARIPMIGLGV-----YQSEPGPETYNAILTSLKLGYRHIDTAEIYGN 55

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           EE VG+    A+ +  + REE+FVTTKL+       + + A + S  +LG+ YI LYL+H
Sbjct: 56  EEDVGR----AVRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLH 111

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
            P   K        +  +TW+ ++D R+    R IGVSNFN T +  L   ++I+P +NQ
Sbjct: 112 APGPPK--------ERADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQ 163

Query: 611 IEVNPTNTQEPLV 649
           +E++P   ++ LV
Sbjct: 164 VELHPWMMRQSLV 176


>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
           Oxidoreductase - Bradyrhizobium japonicum
          Length = 272

 Score =  117 bits (282), Expect = 2e-25
 Identities = 74/197 (37%), Positives = 110/197 (55%)
 Frame = +2

Query: 104 DGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEA 283
           +G  IP + LGT   + +    + E       A+  GYRHIDTA VY +E +VG G+   
Sbjct: 7   NGARIPAIGLGTWELSGRPCARVVEQ------ALRLGYRHIDTAQVYDNEREVGDGVR-- 58

Query: 284 IANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 463
            A+G V R+++F+TTK+W +  A + +  +++ESL +L L  +DL L+H+P +  P    
Sbjct: 59  -ASG-VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSHVP---- 112

Query: 464 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP 643
                 ET   +  ARQ+GL R IGVSNF    I + V+ S    V NQ+E +P   Q  
Sbjct: 113 ----LAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAK 168

Query: 644 LVAHCQSLGIAVMAYSP 694
           + A C   G+A++AYSP
Sbjct: 169 VRAACDQHGLALVAYSP 185


>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=1; Leuconostoc mesenteroides subsp.
           mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
           diketogulonate reductase family - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 288

 Score =  117 bits (282), Expect = 2e-25
 Identities = 74/203 (36%), Positives = 110/203 (54%), Gaps = 4/203 (1%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  +P +  G  +  A+E+      +QAV  AI AGYR IDTA VY +E + GQG+ 
Sbjct: 6   LNNGAQMPQLGFGVFQIPAEET------KQAVVDAINAGYRSIDTARVYGNEAETGQGVN 59

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
           EAIAN +V REELF+TTKLW  + + +    A+ +SLKKLG DY DL L+H P       
Sbjct: 60  EAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG----- 114

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNP 625
                D    ++ + +A+  G  +SIG+SNF   +    +    + +   P I+QIE +P
Sbjct: 115 -----DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHP 169

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              ++         G+ + A+ P
Sbjct: 170 YYQEKVARQLHDKYGVQIEAWGP 192


>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
           Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 287

 Score =  117 bits (281), Expect = 3e-25
 Identities = 71/204 (34%), Positives = 112/204 (54%), Gaps = 2/204 (0%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P ++L  G  +P++ LGT     K  D  ++++Q+V  A++AGYR  DTAAVY +E  +G
Sbjct: 4   PSVRLMSGTQMPLLGLGT----YKLQDH-EQLKQSVSCALQAGYRAFDTAAVYGNEAHLG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--I 439
           Q + E +    + RE++F+ +KL    H        L+ SL++L  +YIDLYLIH+P   
Sbjct: 59  QVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGME 117

Query: 440 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
              P+DS  +    ++W  +++    G  ++IGVSN+ A  I  L+++  + P + QIE 
Sbjct: 118 GLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIEC 177

Query: 620 NPTNTQEPLVAHCQSLGIAVMAYS 691
            P   Q  L   C   GI   AYS
Sbjct: 178 QPKLIQRELRDLCMETGIHFQAYS 201


>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
           n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
           reductase B - Yersinia pestis
          Length = 267

 Score =  117 bits (281), Expect = 3e-25
 Identities = 73/193 (37%), Positives = 111/193 (57%), Gaps = 1/193 (0%)
 Frame = +2

Query: 113 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 292
           +IP+  LGT R   ++   ID V QA    +  GYR IDTA +Y++E  VGQ I E+  N
Sbjct: 2   SIPVFGLGTFR--LQDQIVIDSVSQA----LTLGYRAIDTAQIYENEAPVGQAIQESGIN 55

Query: 293 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 472
               R+ELF+TTK+W    ++D+++P+L+ES++KL  DY+DL LIH+P    P+   D +
Sbjct: 56  ----RDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP---SPN---DEV 105

Query: 473 DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV-INQIEVNPTNTQEPLV 649
              E    +  A+ LGL R IG+SNF    + + ++      +  NQIE++P      +V
Sbjct: 106 SVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVV 165

Query: 650 AHCQSLGIAVMAY 688
              +  GIAV +Y
Sbjct: 166 DFAKQNGIAVTSY 178


>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
           - Apis mellifera
          Length = 321

 Score =  116 bits (280), Expect = 4e-25
 Identities = 72/214 (33%), Positives = 118/214 (55%), Gaps = 13/214 (6%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I L +G  +PI+  GT +   KE      +  A+  A+EAGYRHIDTA  Y++E+ +G  
Sbjct: 6   ILLPNGELMPIIGFGTWQAQEKE------LEDALNIALEAGYRHIDTATSYENEKVIGDV 59

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 448
           +     +  + R ++F+ TKL    +  + V   ++ SL+ L L+Y+DLYLIH PI  + 
Sbjct: 60  LKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEK 119

Query: 449 ------PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
                 P D   +I      +++E W  M+   + G  ++IG+SNFN +QI R++ N+ +
Sbjct: 120 VGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKM 179

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +  + QIE++    Q+ LV  C+   I + AYSP
Sbjct: 180 KISMLQIELHVYFQQKELVKFCKQENIPITAYSP 213


>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
           Saccharomycetales|Rep: Conjugated polyketone reductase
           C1 - Candida parapsilosis (Yeast)
          Length = 304

 Score =  116 bits (280), Expect = 4e-25
 Identities = 76/220 (34%), Positives = 124/220 (56%), Gaps = 12/220 (5%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKE--SDSIDEVRQAVYWAIEAGYRHIDTAAVY 244
           M++     +L++GN IP VA GTG    K   +D   ++   +  A+ +G+RHID A +Y
Sbjct: 1   MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 60

Query: 245 QDEEQVGQGIAEAIANGLVTREELFVTTKL------WNDKHARDQ-VVPALQESLKKLGL 403
              +++G     A+ N  + R+++F+T K       ++ KH++ Q    AL+  L+ LGL
Sbjct: 61  GTNKEIGI----ALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 116

Query: 404 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV-S 580
           +Y+DLYLIHFP  +   +     D +E W+ ++ A+  GLAR+IGVSNF    +  ++ +
Sbjct: 117 EYVDLYLIHFPYIS---EKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDA 173

Query: 581 NSYIRPVINQIEVNP-TNTQEP-LVAHCQSLGIAVMAYSP 694
           N+   PV+NQIE +     Q P +V + Q  GI + AY P
Sbjct: 174 NTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGP 213


>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
           ENSANGP00000029046 - Anopheles gambiae str. PEST
          Length = 331

 Score =  116 bits (279), Expect = 6e-25
 Identities = 72/213 (33%), Positives = 116/213 (54%), Gaps = 14/213 (6%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN G  IP+   GT +   +E      + Q + +A+EAGYRHIDTA VY++EE +G  +
Sbjct: 35  KLNTGFDIPLAGFGTYQIHGQEL-----IYQVLDYALEAGYRHIDTAVVYRNEEYIGTAL 89

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPAL-QESLKKLGLDYIDLYLIHFP-IATK 448
              +    + RE++F+T+KL +     +  V  + ++SL  L  DY+DLYLIH+P ++ K
Sbjct: 90  KTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGK 149

Query: 449 ----------PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYI 592
                         PDN+ Y   +W  +    + G  RSIGVSN+    +  ++++   I
Sbjct: 150 CGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGI 209

Query: 593 RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
            P +NQ+E +P   Q  L+ +C+  GI + AYS
Sbjct: 210 VPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYS 242


>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 287

 Score =  116 bits (278), Expect = 7e-25
 Identities = 66/196 (33%), Positives = 111/196 (56%), Gaps = 2/196 (1%)
 Frame = +2

Query: 110 NTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI- 286
           N +P++ +GT +   +E      +RQ +    + GYR IDTA VY +E ++G+ + + + 
Sbjct: 9   NNMPLIGIGTWQVQKEEI-----LRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLP 63

Query: 287 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 466
           ANGL  RE++++T+KL        +   +++ESL  L ++Y+DL LIH+P ++   ++P 
Sbjct: 64  ANGL-KREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPA 122

Query: 467 NIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP 643
           N    +E+W  M +    G  RS+GVSNF    +  L  +S + P +NQ+E +P   Q+ 
Sbjct: 123 NKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDD 182

Query: 644 LVAHCQSLGIAVMAYS 691
           LV +C    I   AYS
Sbjct: 183 LVKYCNENNIHFQAYS 198


>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
           terreus NIH2624|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 292

 Score =  116 bits (278), Expect = 7e-25
 Identities = 71/186 (38%), Positives = 103/186 (55%), Gaps = 6/186 (3%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKE--SDSID-EVRQAVYWAIEAGYRHIDTAAVYQDEE 256
           P + L DGN +PI+  GTG    K+  +D  + E+ + +  A+E G+ HID A  Y  E 
Sbjct: 4   PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63

Query: 257 QVGQGIAEAIANGLVTREELFVTTKL---WNDKHARDQVVPALQESLKKLGLDYIDLYLI 427
           +VG  I E+   G + RE+LF+TTK+   W D      V  AL  SL++L LDY+DLYL+
Sbjct: 64  EVGIAIRES---G-IPREQLFITTKVLEGWKD------VPGALDASLERLQLDYVDLYLL 113

Query: 428 HFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 607
           H P        P+  D    W+G++  +  G ARSIGVSNF    +  ++    + P IN
Sbjct: 114 HNPYVI-----PNLTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAIN 168

Query: 608 QIEVNP 625
           Q+E +P
Sbjct: 169 QLEYHP 174


>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Streptococcus agalactiae|Rep:
           Oxidoreductase, aldo/keto reductase family -
           Streptococcus agalactiae H36B
          Length = 245

 Score =  115 bits (277), Expect = 1e-24
 Identities = 74/200 (37%), Positives = 112/200 (56%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN+G  IP +    G G  +  D + E  Q+V  A++ GYR IDTA+ Y +EE VG+   
Sbjct: 9   LNNGVKIPSL----GFGVFQIDDPL-ECEQSVLDALQVGYRLIDTASGYLNEEAVGR--- 60

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 457
            AI    + R+E+FV TKLW    + ++  PA+  +LK+L LDYI+LYLIH P+      
Sbjct: 61  -AIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG----- 114

Query: 458 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 637
                DY    + ++ A +   A +IGVSNF+  ++  L+ ++ I P +NQI++NP +  
Sbjct: 115 -----DYYGACRALEKAYEERKALAIGVSNFSNGRVQDLILHNKIIPAVNQIQMNPFHPA 169

Query: 638 EPLVAHCQSLGIAVMAYSPF 697
           +  V      GI  MA+ PF
Sbjct: 170 KDQVEWLSKKGIHTMAWGPF 189


>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
           Alphaproteobacteria|Rep: Aldo/keto reductase -
           Mesorhizobium sp. (strain BNC1)
          Length = 274

 Score =  115 bits (276), Expect = 1e-24
 Identities = 73/194 (37%), Positives = 110/194 (56%)
 Frame = +2

Query: 107 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 286
           G TIP +    G G  + SD+  EV + +  A+EAG+RH DTA +YQ+E  +G+ +  A 
Sbjct: 8   GATIPAL----GFGVFRMSDA--EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERAG 61

Query: 287 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 466
           A     RE+LF+TTK+W D ++ D+   ++ ESL+KL +D +DL L+H+P    P  +  
Sbjct: 62  AR----REDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWPAHEVPVAA-- 115

Query: 467 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 646
               +E    ++DA   G  R IGVSN N  Q+   ++ S    V NQ+E++P   Q  L
Sbjct: 116 ---QIERLNAVKDA---GKTRFIGVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHSL 169

Query: 647 VAHCQSLGIAVMAY 688
           VA  +   +AV AY
Sbjct: 170 VAAARDSAVAVTAY 183


>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 297

 Score =  115 bits (276), Expect = 1e-24
 Identities = 65/202 (32%), Positives = 113/202 (55%), Gaps = 3/202 (1%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +LN G  IP V  GT + T       + V  A+  A+ AGYR  DTA  Y +E+++G+ +
Sbjct: 14  KLNSGYNIPFVGFGTYKVTG------ENVPPAIDAALTAGYRMFDTAKYYLNEKELGEAL 67

Query: 275 AEAIANGLVTREELFVTTKLWND-KHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
              +    ++R ++F+T+K + + K+ R+     ++ESL+ L  DYID+YL+H+P     
Sbjct: 68  KILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDS 127

Query: 452 D-DSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
           D D  +N +Y +  ++ +++A+  G  RSIGVSN+    +  L + + + P  NQ+E +P
Sbjct: 128 DNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHP 187

Query: 626 TNTQEPLVAHCQSLGIAVMAYS 691
              + PL  +C+   I   A+S
Sbjct: 188 HFARIPLQKYCKEKNIFFQAFS 209


>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
           Griffithsia japonica|Rep: Mannose 6-phosphate reductase
           - Griffithsia japonica (Red alga)
          Length = 174

 Score =  102 bits (245), Expect(2) = 2e-24
 Identities = 51/110 (46%), Positives = 73/110 (66%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           L  G  +P+   GT +       S++E  QAV  A+ AGYRHID AAVY +E  VG  I+
Sbjct: 8   LQSGAKMPLNGFGTWKA------SVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61

Query: 278 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 427
           +AI+ G+V RE+LF+T+K+WN  HA D+VV + ++SLK   +DY DL+L+
Sbjct: 62  KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111



 Score = 33.1 bits (72), Expect(2) = 2e-24
 Identities = 17/57 (29%), Positives = 29/57 (50%)
 Frame = +2

Query: 503 DARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGI 673
           D   L L R IGVSN++   +   ++ + I+P +NQ E +    +  L   C+  G+
Sbjct: 104 DYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCREFGV 160


>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
           Clostridium beijerinckii NCIMB 8052|Rep:
           2,5-didehydrogluconate reductase - Clostridium
           beijerinckii NCIMB 8052
          Length = 289

 Score =  114 bits (275), Expect = 2e-24
 Identities = 63/174 (36%), Positives = 95/174 (54%)
 Frame = +2

Query: 173 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 352
           ++   AV  AI+ GYRH DTA +Y +E+ +G     AI    + REE F+T+K+WN  H 
Sbjct: 30  EDFETAVGEAIKIGYRHFDTAKIYGNEKDLGL----AIEKSQIPREEFFITSKVWNTDHG 85

Query: 353 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 532
            +    A +++ KKL ++Y+D+YLIHF  +           YLETW  M++    G  + 
Sbjct: 86  YEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------YLETWHAMEELYLQGKIKV 135

Query: 533 IGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IGV+NF    +  L+ +S I P+INQIE +P   Q  L  +     I   A++P
Sbjct: 136 IGVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAP 189


>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
           Parvularcula bermudensis HTCC2503|Rep: Putative
           uncharacterized protein - Parvularcula bermudensis
           HTCC2503
          Length = 278

 Score =  114 bits (275), Expect = 2e-24
 Identities = 71/192 (36%), Positives = 108/192 (56%)
 Frame = +2

Query: 119 PIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 298
           PI  LG G    +  D+    R +   AIE GYRHID AA+Y++E++VG+GI ++   G 
Sbjct: 10  PIPRLGFGTWQLEGEDA----RTSTRTAIETGYRHIDGAAIYKNEKKVGEGIKDS---G- 61

Query: 299 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 478
           + R+ELFVTTK+WN+   + +   A+ ESL +LGLDY++L L+H+PI   P    D +  
Sbjct: 62  IPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPINDMP--IADQVGP 119

Query: 479 LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHC 658
           L       + ++ G A+ IG+SN+N  Q    VS S       Q E +P   Q+P++   
Sbjct: 120 L------AEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKTA 173

Query: 659 QSLGIAVMAYSP 694
           +   +   +YSP
Sbjct: 174 RGFDMMFTSYSP 185


>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG6084-PA, isoform A - Tribolium castaneum
          Length = 493

 Score =  113 bits (272), Expect = 4e-24
 Identities = 70/203 (34%), Positives = 114/203 (56%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P  +LN+G  IP+       G A   D  +   + V   + + YR +D  +++++E++ G
Sbjct: 9   PIAKLNNGIEIPVF------GLAAPQDFFEV--ENVQLVVSSNYRLMD-CSIFENEKRFG 59

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
             + + I  G + R++LF+ +K     +  + V  AL ++LKKL + Y+DLYLI  P A 
Sbjct: 60  VALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPAC 118

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 625
           K  +       +ETW+ M+      L R+IG+SNFN+ QI R++ N  IRP +NQI+ +P
Sbjct: 119 KDHN------LIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVNQIQCHP 172

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
              Q  L  +C + GIAV++YSP
Sbjct: 173 YLNQAKLRKYCSNNGIAVISYSP 195



 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 51/117 (43%), Positives = 71/117 (60%), Gaps = 12/117 (10%)
 Frame = +2

Query: 380 ESLKKLGLDYIDLYLIHFPIATKPDDS------------PDNIDYLETWQGMQDARQLGL 523
           ESLK L LDY+D+YL+H+P A K   S            P ++D+++TW+ M+   +  L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330

Query: 524 ARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            +SIG+SNFN+ QI RL+ ++ I PVINQIE +P   Q  L   C   GI V +YSP
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSP 387


>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
           reductase; n=5; Pezizomycotina|Rep: Related to 2,
           5-diketo-D-gluconic acid reductase - Neurospora crassa
          Length = 289

 Score =  113 bits (272), Expect = 4e-24
 Identities = 69/207 (33%), Positives = 117/207 (56%), Gaps = 6/207 (2%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           ++L++G +IP + LG    +  E+       +AV WA+ AGYR  D+A  Y +E + GQ 
Sbjct: 13  VKLSNGLSIPQIQLGLYMMSGPETT------RAVRWALGAGYRGFDSAQWYYNEREAGQA 66

Query: 272 IAEAIAN-----GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 436
           I   +++     GL TR+++  T+KL ++    D V  ++ +S+K  GL YIDL+L+H P
Sbjct: 67  ILSFLSSPENTAGL-TRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSP 125

Query: 437 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY-IRPVINQI 613
           +  +          L +W+ ++DA   G  +  GVSN+    +  ++S  + I+P++NQI
Sbjct: 126 LGGREAR-------LTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPLVNQI 178

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           E +P NTQ  + A C+  GI + AY+P
Sbjct: 179 ECHPFNTQPEIRAACEKYGIVIEAYAP 205


>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 275

 Score =  113 bits (272), Expect = 4e-24
 Identities = 62/170 (36%), Positives = 100/170 (58%), Gaps = 1/170 (0%)
 Frame = +2

Query: 188 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 367
           +VY A++ GYRHID+A +Y +E   G+ I + +      RE+++ T+KL ND       +
Sbjct: 32  SVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTL 90

Query: 368 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 547
            ++  S+K  GL YIDL+L+H P            D +E+W+ ++   + G  R+IGVSN
Sbjct: 91  SSIDASVKACGLGYIDLFLLHSPYG----------DRIESWKALEKGVEEGKLRAIGVSN 140

Query: 548 FNATQITRLV-SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           F    I  L+ S+  I P +NQIE++P  +Q+ +V +C+S GI + AY+P
Sbjct: 141 FGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAP 190


>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
           mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
          Length = 273

 Score =  113 bits (271), Expect = 5e-24
 Identities = 69/201 (34%), Positives = 108/201 (53%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LNDG+++P +  G  +    +++S+      V    + GYR +DTAA Y++EE VG+G
Sbjct: 7   VVLNDGHSMPAIGQGVYQLNPAQAESM------VALGYDLGYRAVDTAAWYENEEGVGEG 60

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           +    A         F+TTKL      R     AL +S++ LG+  ++LYLIH+P     
Sbjct: 61  LRSRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP----- 108

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
               D   Y ETWQ +   R +G A SIGVSNF    +  ++++S + P +NQIE++P  
Sbjct: 109 --GQDRKRYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYF 166

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q+ L A+    GI   ++SP
Sbjct: 167 QQKELRAYHAERGIVTTSWSP 187


>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 288

 Score =  112 bits (270), Expect = 7e-24
 Identities = 68/206 (33%), Positives = 113/206 (54%), Gaps = 4/206 (1%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + LN+   +P++ LGT R   +E     +   AV  A++AGYR  DTAAVY++E  +G
Sbjct: 6   PSVLLNNDIQMPLLGLGTFRLQGQE-----DTYSAVDAALKAGYRAFDTAAVYRNEAHLG 60

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--- 436
             +   +    ++RE++F+T+KL   K    +     Q+SL++LGL YIDLYLIH+P   
Sbjct: 61  HALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQ 119

Query: 437 -IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
            +      +P+N    ++W+ +++    G  R+IGVSN+    +  L+ +  + P + Q+
Sbjct: 120 GLPVGDKRNPEN--RAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQV 177

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYS 691
           E +P   Q  L   C+  G+   AYS
Sbjct: 178 EFHPKLLQNDLRGLCKIRGVCFQAYS 203


>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
           AkrI - Butyrivibrio fibrisolvens
          Length = 172

 Score =  112 bits (270), Expect = 7e-24
 Identities = 57/153 (37%), Positives = 94/153 (61%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I+LN+G  IP+     G GT K  D  +E   +V  A++ GYRHIDTAA Y++E+ V   
Sbjct: 8   IKLNNGTAIPMF----GYGTYKIKDQ-NEAYNSVRLALKNGYRHIDTAAFYENEKFVANA 62

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I + +      RE++FVT+K W  +   D+ + A ++++ ++ +DY+DLYL+H+P +   
Sbjct: 63  IKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNF 550
           DD  +N +  +TW+ M +  + G  ++IGVSNF
Sbjct: 123 DDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNF 154


>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
           protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
           family 1 member C-like protein 2 - Homo sapiens (Human)
          Length = 320

 Score =  112 bits (270), Expect = 7e-24
 Identities = 79/215 (36%), Positives = 112/215 (52%), Gaps = 32/215 (14%)
 Frame = +2

Query: 146 GTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 325
           G +    S  +V +AV  AI+AGYRH D A  Y +E +VG GI   I  G V RE+LF+ 
Sbjct: 8   GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67

Query: 326 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 430
           TKLW   H +  V  A +   ++LK   LD                       +   L H
Sbjct: 68  TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127

Query: 431 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 595
             +   P D+S    P + D+L+TW+ M+D    GL ++IGVSNFN  Q+ RL++   +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187

Query: 596 --PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
             P+ NQIE +P  TQ+ L++ CQS  ++V AY P
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRP 222


>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 302

 Score =  112 bits (269), Expect = 9e-24
 Identities = 74/208 (35%), Positives = 115/208 (55%), Gaps = 5/208 (2%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDE--VRQAVYWAIEAGYRHIDTAAVYQDEEQ 259
           P ++L++G  IP +  G+G    +     +E  +  AV  AI AG+ HIDTA  Y  E+Q
Sbjct: 4   PKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQ 63

Query: 260 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
           +G+ I E+   G V R+++F+T+K      A D  + ++   LK L  DY DL+LIH P 
Sbjct: 64  IGEAIKES---G-VPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLIHVP- 117

Query: 440 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
              P+D   N D  + W  ++   + GLA++IGVSN +  ++  ++  + I+P +NQIE 
Sbjct: 118 ---PNDDI-NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEF 173

Query: 620 NPTNTQEP---LVAHCQSLGIAVMAYSP 694
           +P   QEP   +V  C+   I V  YSP
Sbjct: 174 HPL-LQEPTPGIVDFCKQHDIVVEGYSP 200


>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
           reductase family - Caulobacter crescentus (Caulobacter
           vibrioides)
          Length = 279

 Score =  111 bits (267), Expect = 2e-23
 Identities = 70/208 (33%), Positives = 113/208 (54%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 250
           M+   P ++  D   + + ALG G    +   ++  V +A    +E GYRHIDTA +Y +
Sbjct: 1   MSKLVPAVRSGD---VLMPALGFGTWQLENGTAVPLVEKA----LEIGYRHIDTAQIYGN 53

Query: 251 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 430
           E  VG     AI N  V R+E+F+TTK+W D+ A   +  + ++SL+KLG+D +DL L+H
Sbjct: 54  ERDVGA----AIRNSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLH 109

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
           +P   KP+     +   ET + +   R  G  R+IG+SNF + Q+      S      +Q
Sbjct: 110 WP---KPE-----VPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQ 161

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +E +P  + + L A    LG+++ A+SP
Sbjct: 162 VEYHPYLSLKTLKAKADQLGVSITAWSP 189


>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 324

 Score =  110 bits (265), Expect = 3e-23
 Identities = 74/196 (37%), Positives = 104/196 (53%), Gaps = 11/196 (5%)
 Frame = +2

Query: 140 GRGTAKESDSI---DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE 310
           G GT +   S+     V+ +V  A++ GYRHID A  Y     V +GI  AI    V RE
Sbjct: 20  GLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAY-GWGSVERGIGAAIRASGVPRE 78

Query: 311 ELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI---HFPIATKPDDSPD-NID- 475
           ++FV TKL N  HA + V   +  SLK LGL Y+        ++    KPD  P  +I+ 
Sbjct: 79  DVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIEL 138

Query: 476 ---YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 646
              +  TW+ M++    G A+ IGVSNF+  ++ RL+S   I PV+NQ+E+NP   Q+ L
Sbjct: 139 SRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQL 198

Query: 647 VAHCQSLGIAVMAYSP 694
           +  C    I V AY P
Sbjct: 199 LRFCHEHEIHVTAYGP 214


>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
           precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
           complete genome. precursor - Aspergillus niger
          Length = 351

 Score =  110 bits (265), Expect = 3e-23
 Identities = 79/215 (36%), Positives = 109/215 (50%), Gaps = 21/215 (9%)
 Frame = +2

Query: 113 TIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 292
           T P V LGT +G A        V++AV  A+  GYRHIDTA  Y +E +VG    EAI  
Sbjct: 45  TFPAVGLGTFQGDAGNRG----VKEAVLQALRCGYRHIDTATAYGNEIEVG----EAIKE 96

Query: 293 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDY-IDLYLIHFPIATKP---DDS 460
             + REE+ VTTKL    H    V  AL  SL++L L+Y + ++L      + P      
Sbjct: 97  SRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156

Query: 461 PDN-----------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 589
           PDN                  DY  TW  M+     G  + IGVSNFN  ++ RL+ ++ 
Sbjct: 157 PDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR 216

Query: 590 IRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           I P +NQIE++P   Q  LV  C++ GI ++A+ P
Sbjct: 217 IPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQP 251


>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
           Gammaproteobacteria|Rep: Aldo/keto reductase -
           Shewanella sp. (strain ANA-3)
          Length = 280

 Score =  110 bits (264), Expect = 4e-23
 Identities = 70/200 (35%), Positives = 107/200 (53%), Gaps = 4/200 (2%)
 Frame = +2

Query: 110 NTIPIVA---LGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAE 280
           N  P+ A   LGTG    K++ + D    AV  A+E G RHIDTA +Y +E+ VG    +
Sbjct: 10  NQAPLTAMPMLGTGTFRLKDNAAFD----AVLMALEEGSRHIDTAQIYGNEQAVG----D 61

Query: 281 AIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 460
           AI    + REELF+TTK+W +   +++   ++ +SL  L   Y+DL LIH+P+ +   D 
Sbjct: 62  AINTSGIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNS---DE 118

Query: 461 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV-INQIEVNPTNTQ 637
           P  ++YL   + + D    GL R IGVSNF   Q+ + ++      +  NQ+EV+P    
Sbjct: 119 PSMVEYLSELKAVLDK---GLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLIN 175

Query: 638 EPLVAHCQSLGIAVMAYSPF 697
             +   C+   + V  Y PF
Sbjct: 176 RKVTDFCRQHNVLVTGYMPF 195


>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
           n=1; Haloarcula marismortui|Rep: Oxidoreductase
           aldo/keto reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 274

 Score =  109 bits (263), Expect = 5e-23
 Identities = 72/196 (36%), Positives = 103/196 (52%)
 Frame = +2

Query: 107 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 286
           G ++P + LGT + T +        R+ V  A+  GYRHIDTA  Y +E QVG G+  A 
Sbjct: 8   GTSVPALGLGTWQLTGQSC------RETVETALGMGYRHIDTAQAYGNERQVGLGMDAAA 61

Query: 287 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 466
               V RE++F+TTKL         V  + +ESL KLG DY+DL LIH+P      ++P 
Sbjct: 62  ----VDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP------NTPW 111

Query: 467 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 646
                ET   M D  + GL R IGVSNF+ + + R    S      +Q++ +P   Q  L
Sbjct: 112 MASLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKL 171

Query: 647 VAHCQSLGIAVMAYSP 694
           + +C+   + + AYSP
Sbjct: 172 LDYCRIHDVLLTAYSP 187


>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
           YvgN - Bacillus sp. NRRL B-14911
          Length = 268

 Score =  109 bits (262), Expect = 6e-23
 Identities = 69/207 (33%), Positives = 108/207 (52%), Gaps = 6/207 (2%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAV---YWAIEAGYRHIDTAAVYQDEEQV 262
           I LN+G  +PIV  GT     + +D   ++   +     AIE GYR ID A +Y++EE V
Sbjct: 4   ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEELV 63

Query: 263 GQGIAEAIANGLVTREELFVTTKLWNDKH---ARDQVVPALQESLKKLGLDYIDLYLIHF 433
           G  +AE+     V REE F+TTK+   +    +++    A+  SLK    DY+DL LIHF
Sbjct: 64  GSVLAES----KVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
           PI        D +    TW+  ++  + G  ++IGVSNF    +  L   + ++P +NQI
Sbjct: 120 PIE-------DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQI 172

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++N     + L+A  +   I  +A+ P
Sbjct: 173 QINLKEPNKNLLAVLKDEEITPVAWGP 199


>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
           Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 349

 Score =  109 bits (262), Expect = 6e-23
 Identities = 78/233 (33%), Positives = 128/233 (54%), Gaps = 33/233 (14%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L  G+ IP V LGT R  ++ + ++      V   +E GYRHIDTA  Y D+ +VGQGI
Sbjct: 17  RLLSGHKIPAVGLGTWRSGSQAAHAV------VTAIVEGGYRHIDTAWEYGDQREVGQGI 70

Query: 275 AEAIANGL---------------VTREELFVTTKLWN-----------DKHARDQVVPAL 376
             A+  GL               + R+ + +++ L N            + + ++V PAL
Sbjct: 71  KRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPAL 130

Query: 377 QESLKKLGLDYIDLYLIHFPI-----ATKPDDSPDNIDY-LE-TWQGMQDARQLGLARSI 535
           Q +LK+L L+Y+DLYLIH+PI     A+KP  + D +D+ +E  W+ M++  +  L R+I
Sbjct: 131 QNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKDSLVRNI 190

Query: 536 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           GV NF  T++ +L+  + + P + Q+E++P    + ++  C+   I V AYSP
Sbjct: 191 GVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSP 243


>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
           niger|Rep: Putative frameshift - Aspergillus niger
          Length = 357

 Score =  109 bits (262), Expect = 6e-23
 Identities = 79/211 (37%), Positives = 118/211 (55%), Gaps = 12/211 (5%)
 Frame = +2

Query: 98  LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 277
           LN G  IP  ALG G  T ++ DS +E    V   ++ G R IDTA VY  E+QVG+GI 
Sbjct: 40  LNTGAKIP--ALGVG--TFQDPDSQEET---VCQVLQRGMRLIDTARVYGVEQQVGRGIK 92

Query: 278 EAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK-- 448
           ++   G V REE+F+ TKLW ND H  D V  A+ +SL+ L   Y+DL L+H+P   K  
Sbjct: 93  KS---G-VPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRG 147

Query: 449 ----PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 601
               P D+   +      +++TW+ ++   + G  R+IGVSNF+  +I  L+  +   P 
Sbjct: 148 EDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPA 207

Query: 602 INQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++Q+EV+P   Q+      +  GI V+ +SP
Sbjct: 208 VHQMEVHPYLQQKGFNEWLREKGIHVVQFSP 238


>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
           Schizosaccharomyces pombe|Rep: Xylose and arabinose
           reductase - Schizosaccharomyces pombe (Fission yeast)
          Length = 283

 Score =  109 bits (261), Expect = 8e-23
 Identities = 73/206 (35%), Positives = 110/206 (53%), Gaps = 1/206 (0%)
 Frame = +2

Query: 80  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 259
           ++  + L +G  IP   +G G    K ++    V QA    +++GYRHIDTAAVY +E+ 
Sbjct: 7   ESTTVTLTNGMVIP--RIGFGAFMLKYNECYGLVTQA----LDSGYRHIDTAAVYGNEDI 60

Query: 260 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
            G+ I +      V R ++F+T+KL N          A++ SL  LG  YIDL+LI  P 
Sbjct: 61  CGKAIVDWCEKNNVKRTDIFLTSKLANCSDYY-STRAAIRSSLHHLG-TYIDLFLIQSPA 118

Query: 440 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL-VSNSYIRPVINQIE 616
             K          + +W+ M++    G  RS+GVSN+    +  L  SN    P +NQIE
Sbjct: 119 GGKK-------SRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIE 171

Query: 617 VNPTNTQEPLVAHCQSLGIAVMAYSP 694
           ++P  +Q+ +V +CQS  IA+ AYSP
Sbjct: 172 LHPFLSQDDIVKYCQSHDIAIEAYSP 197


>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
           Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
           Leishmania major strain Friedlin
          Length = 372

 Score =  108 bits (260), Expect = 1e-22
 Identities = 73/224 (32%), Positives = 108/224 (48%), Gaps = 23/224 (10%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I + D +TIP +  GT R        + E   AV +A+  GYRH+D A  Y +E  VG+ 
Sbjct: 22  IAMRDSHTIPQLGFGTYRLP------VSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEA 75

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           +A+A+      RE+LFVT+KLW      D V  A + +L  L LDY+DLYLIH+P+  + 
Sbjct: 76  LAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRH 135

Query: 452 ---------------DDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
                          D +P    ++  L+TW  M      GL +SIG++N     +  LV
Sbjct: 136 TPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLV 195

Query: 578 -----SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
                +     PV+NQ+E +P      L+    S  + + AY P
Sbjct: 196 KAVAEAKLAHLPVLNQVEHHPGIVDGDLIGCLGSHDMLMAAYCP 239


>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
           cryohalolentis K5|Rep: Aldo/keto reductase -
           Psychrobacter cryohalolentis (strain K5)
          Length = 282

 Score =  108 bits (259), Expect = 1e-22
 Identities = 71/195 (36%), Positives = 108/195 (55%), Gaps = 2/195 (1%)
 Frame = +2

Query: 116 IPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANG 295
           IP++ LGT + T +  D ID V Q     +  GY HIDTA  Y +E +VG+GI ++   G
Sbjct: 16  IPVLGLGTWQSTGQ--DCIDVVSQG----LRMGYEHIDTAQAYGNEVEVGKGIKQS---G 66

Query: 296 LVTREELFVTTKLWND--KHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDN 469
            V R++ F+TTK++ D  K   +++V A + SL+ L  DY+DL L+H+P         D 
Sbjct: 67  -VARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------DDR 117

Query: 470 IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLV 649
           +   ET   + + ++ GL R+IGVSNFN   I      + +  V+NQ+E +P   Q+ L 
Sbjct: 118 VPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIKQKTLQ 177

Query: 650 AHCQSLGIAVMAYSP 694
               +  I + AYSP
Sbjct: 178 TFLNNHHILLEAYSP 192


>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
           Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
           protein - Sulfitobacter sp. NAS-14.1
          Length = 274

 Score =  108 bits (259), Expect = 1e-22
 Identities = 66/174 (37%), Positives = 90/174 (51%)
 Frame = +2

Query: 173 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 352
           D V   V  A+  G+RHIDTA  YQ+EEQVG+G+  A     V R+E+F+TTK+  +  +
Sbjct: 24  DTVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRAD----VRRDEVFLTTKILPEHFS 79

Query: 353 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 532
            +    A   SLK+LG DY+DL L+H+P    P          ET   + D    G  R 
Sbjct: 80  PEAFTAAADASLKRLGTDYVDLLLLHWPSKEVP--------IAETIGALNDLISAGKVRH 131

Query: 533 IGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
            GVSNF    + +  +        NQIE++P   Q  ++AH  S GI   AYSP
Sbjct: 132 GGVSNFTMDMVDQAQAALNTPLAANQIELHPLIDQTRMIAHLASKGIPAEAYSP 185


>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
           reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
           alpha-keto amide reductase - Saccharomyces cerevisiae
           (Baker's yeast)
          Length = 312

 Score =  108 bits (259), Expect = 1e-22
 Identities = 74/207 (35%), Positives = 107/207 (51%), Gaps = 8/207 (3%)
 Frame = +2

Query: 98  LNDGNTIPIVAL-GTGRGTAK--ESD---SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 259
           LN+GN IP +A+ GTG    K  E+D   S   V Q VY     G  HID A +Y+   +
Sbjct: 10  LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69

Query: 260 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
           VG+    A++     R  +F+T K        D     L  +LKK+G DY+DLYL+H P 
Sbjct: 70  VGK----ALSLTEKPRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF 125

Query: 440 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
            +K     + +   E W+ M+   + G A++IGVSNF    + R++  + ++P +NQIE 
Sbjct: 126 VSK---EVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEF 182

Query: 620 NP-TNTQEP-LVAHCQSLGIAVMAYSP 694
           +P    Q P +   CQ   I V AYSP
Sbjct: 183 SPFLQNQTPGIYKFCQEHDILVEAYSP 209


>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
           Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
           Bradyrhizobium sp. (strain ORS278)
          Length = 273

 Score =  107 bits (258), Expect = 2e-22
 Identities = 67/185 (36%), Positives = 101/185 (54%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G GT +   ++   R AV  A+  GYRHIDTA +Y +E+ +G  +A A     + RE+L 
Sbjct: 15  GLGTFRMQGTV--CRDAVESALALGYRHIDTAEMYANEDAIGAALAAA----QIAREDLH 68

Query: 320 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 499
           VTTK+W +  A D +  A   SLKKL LD++DLYLIH+P AT        ++     + +
Sbjct: 69  VTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP-AT-------GMNLPAAMETL 120

Query: 500 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAV 679
              +Q G  R+IGV+NF    + + V +       NQ+E +    Q  L+A+ +S  I +
Sbjct: 121 MALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKLMAYMKSRSIPL 180

Query: 680 MAYSP 694
           +AY P
Sbjct: 181 VAYCP 185


>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
           Oceanicola granulosus HTCC2516|Rep:
           2,5-didehydrogluconate reductase - Oceanicola granulosus
           HTCC2516
          Length = 275

 Score =  107 bits (257), Expect = 3e-22
 Identities = 73/193 (37%), Positives = 98/193 (50%), Gaps = 1/193 (0%)
 Frame = +2

Query: 119 PIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 298
           P +  G G GT       D +  A+  A+E GYRH+DTA  Y  E +VG+ I  A   GL
Sbjct: 9   PEIMPGLGFGTYGRQGE-DGI-SAILCALETGYRHLDTAQDYDTEAEVGEAIRRA---GL 63

Query: 299 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 478
             RE LFVTTK+         +VP++  SL+ +GLD  DL LIH+P    P+      DY
Sbjct: 64  -PREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWP---APNGERPLSDY 119

Query: 479 LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI-NQIEVNPTNTQEPLVAH 655
           +     + +AR  GL R +GVSNF    +T   +     P++ NQ+E+NP      L  H
Sbjct: 120 IPQ---LAEARAQGLTRHVGVSNFPVALLTEARALLGDVPILTNQVELNPWFRNRTLADH 176

Query: 656 CQSLGIAVMAYSP 694
           C   GI V  Y P
Sbjct: 177 CMGAGIRVTCYQP 189


>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
           Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
           Caenorhabditis elegans
          Length = 321

 Score =  107 bits (256), Expect = 3e-22
 Identities = 72/204 (35%), Positives = 107/204 (52%), Gaps = 1/204 (0%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P   L++   +P++ LGT        D++      ++   + GYR IDTA  Y  E+Q+G
Sbjct: 3   PTTVLSNNVEMPLIGLGTTHSGGYYHDAV------LHSIKKCGYRLIDTAKRYGVEKQLG 56

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
                A+ N  V REE+F++TKLW      D+V  A Q S +KL  DY+D+Y+IH P   
Sbjct: 57  I----AVKNCSVPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP--Q 109

Query: 446 KPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 622
            PD   +  +  E TW+ M+   +    RSIGVSN++   +  L+  + I P  NQ+E++
Sbjct: 110 LPDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELH 169

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P   Q  L  +C  LGI  M Y P
Sbjct: 170 PWFHQADLKNYCDELGILTMGYCP 193


>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
           penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
          Length = 285

 Score =  106 bits (254), Expect = 6e-22
 Identities = 64/202 (31%), Positives = 111/202 (54%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I+L +G  +PI+ LG  +   +  ++   + +A+    + GYR IDTA VY +EE VG  
Sbjct: 4   IKLANGLHMPIIGLGVYKAEGENCENT--IIKAID---DYGYRMIDTAQVYFNEEFVGNA 58

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I +      + RE++F+TTK+W   +  +  + ++ +SLKKL  +YIDL L+H P     
Sbjct: 59  IKQT----KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG--- 111

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                  DY   W+ ++   + G+ ++IGVSNF A ++     +  ++PVINQIE++P  
Sbjct: 112 -------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLR 164

Query: 632 TQEPLVAHCQSLGIAVMAYSPF 697
            +   +      G+AV +++ F
Sbjct: 165 QRIEDLHWNNKYGVAVESWASF 186


>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 301

 Score =  106 bits (254), Expect = 6e-22
 Identities = 66/204 (32%), Positives = 107/204 (52%), Gaps = 5/204 (2%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           + +DG  +P + LG  R   +    +D   +A   A+++GYR  DTA +Y++E  +G  +
Sbjct: 13  KFSDGYEMPKIGLGISR--IETQQDLDVSIEA---ALKSGYRQFDTANLYKNETFLGNSL 67

Query: 275 AEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPI---A 442
            + +    +TRE++F+TTK+   +++  ++    L  SL  L  DY+DL LIH+P     
Sbjct: 68  KKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDT 127

Query: 443 TKPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 619
              DD   N    +  WQ ++ A++ G  RSIGVSN+    +  +   + IRPV+NQ E 
Sbjct: 128 GNDDDYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYEY 187

Query: 620 NPTNTQEPLVAHCQSLGIAVMAYS 691
            P  T+  L   C    I V +YS
Sbjct: 188 QPYLTRPTLKKFCDLNNIVVQSYS 211


>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
           Helicobacter hepaticus|Rep: Putative uncharacterized
           protein - Helicobacter hepaticus
          Length = 270

 Score =  105 bits (253), Expect = 8e-22
 Identities = 69/202 (34%), Positives = 106/202 (52%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           + LN+G  +PI+ LGT   T K        ++A+  AIE GYR  D+A +Y +E ++G  
Sbjct: 4   LTLNNGVKMPILGLGTYSLTGKAG------QKAMSEAIEVGYRLFDSAQMYNNEAELGAA 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           I  A+  G + REE F+ TKL  +  + D    ++++SLK LGLDYID  LIH P +   
Sbjct: 58  INAAVKGG-IKREEFFIQTKLL-ESSSEDLAKKSIEKSLKTLGLDYIDSLLIHMPYSQSK 115

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                       ++ M+   + G+ R IG+SNF A   +  V +  + P INQ E +   
Sbjct: 116 ----------AMYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLL 165

Query: 632 TQEPLVAHCQSLGIAVMAYSPF 697
            Q+PL    +S    + ++SPF
Sbjct: 166 QQKPLREAMKSKKTLLQSWSPF 187


>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
           baltica OS145|Rep: Aldo/keto reductase - Idiomarina
           baltica OS145
          Length = 263

 Score =  105 bits (253), Expect = 8e-22
 Identities = 66/174 (37%), Positives = 96/174 (55%), Gaps = 1/174 (0%)
 Frame = +2

Query: 176 EVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR 355
           E+   V  AI+ GY HIDTA  Y +E  VG+ +A+       T +++FVTTK+W +K A 
Sbjct: 16  ELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKDVFVTTKVWYEKLAY 69

Query: 356 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 535
             V+ +LQ S  KL  D IDL LIH+P    P+   D +   ET   +Q A+Q GL + +
Sbjct: 70  QDVLDSLQVSRDKLQRDTIDLALIHWP---SPN---DEVPVEETLDALQKAQQDGLIKHL 123

Query: 536 GVSNFNATQITRLVSNSYIRPVI-NQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           GVSNF    + R  ++     ++ NQIEV+P      +   C+ +G+ V AY P
Sbjct: 124 GVSNFTIDLLNRAAAHVGKDEILTNQIEVHPFFQNHAITDACKQMGVKVTAYLP 177


>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 313

 Score =  105 bits (253), Expect = 8e-22
 Identities = 72/216 (33%), Positives = 109/216 (50%), Gaps = 8/216 (3%)
 Frame = +2

Query: 71  MAVQAPCIQLNDGNTIPIVAL-GTGRGTAKESDS----IDEVRQAVYWAIEA-GYRHIDT 232
           M++      LN+GN IP +++ GTG    K   S     DE+ + + +A+   G  HID 
Sbjct: 1   MSLTQKFFDLNNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDA 60

Query: 233 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYI 412
           A  Y    +    +A+A+      R E+F+T K        +  +  L   LK LGLDY+
Sbjct: 61  AECYGTYPE----LAKALKESSKPRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYV 116

Query: 413 DLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 592
           DLYLIH P      +   ++   + W+ M+   + G A+SIGVSNF+   I  ++  + I
Sbjct: 117 DLYLIHSPFF--DPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGI 174

Query: 593 RPVINQIEVNP-TNTQEP-LVAHCQSLGIAVMAYSP 694
           +P +NQIE N     Q P +V +CQ   I + AYSP
Sbjct: 175 KPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSP 210


>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
           oxidoreductase protein; n=1; Spiroplasma citri|Rep:
           Putative aldo/keto reductase oxidoreductase protein -
           Spiroplasma citri
          Length = 263

 Score =  105 bits (252), Expect = 1e-21
 Identities = 62/173 (35%), Positives = 95/173 (54%), Gaps = 3/173 (1%)
 Frame = +2

Query: 185 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 364
           +A+  A++ GY+ IDTA VYQ+EE VG+ I + + +    RE++ + TK+W D       
Sbjct: 19  EAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGNT 78

Query: 365 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQL---GLARSI 535
             A+ ESLK+L + Y+D+ LIH P          N+++ +T +   +  Q    GL   +
Sbjct: 79  TNAVLESLKRLNVTYLDIVLIHRP----------NLNFYKTIKAYVELLQCKAKGLINVV 128

Query: 536 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           GVSNF+   I  L   +   P +NQIE NP N +   V +CQ+  I V +YSP
Sbjct: 129 GVSNFDKDMIEILFEETGAYPNLNQIEFNPFNQRWDRVQYCQNKNILVQSYSP 181


>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
           reductase family; n=5; Lactobacillus|Rep: Aldo/keto
           reductase of diketogulonate reductase family -
           Lactobacillus brevis (strain ATCC 367 / JCM 1170)
          Length = 282

 Score =  105 bits (251), Expect = 1e-21
 Identities = 67/200 (33%), Positives = 108/200 (54%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L DG  +P++    G GT   +D    +  A+  A +AGYR  DTA +Y++E+ +G  I
Sbjct: 11  KLADGRQMPVM----GFGTYLLNDQ-PTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI 65

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 454
            +    GL  RE LF+T+K+       DQ + A++ SLK+L  DY+DL LIH+P+     
Sbjct: 66  QQL---GL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVREH-- 119

Query: 455 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 634
                  + +TW+ ++  +  G  +SIGVSN+    +  L + +   PV+NQ+E +P   
Sbjct: 120 -------FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLN 172

Query: 635 QEPLVAHCQSLGIAVMAYSP 694
           Q+ L  + Q   I   A+SP
Sbjct: 173 QQALADYDQEHDIVTEAWSP 192


>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
           Caenorhabditis elegans|Rep: Putative uncharacterized
           protein - Caenorhabditis elegans
          Length = 287

 Score =  105 bits (251), Expect = 1e-21
 Identities = 64/204 (31%), Positives = 107/204 (52%), Gaps = 4/204 (1%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L +G  IP +ALGT           D++  AV  A++ GYR  DTA  Y++E+ +G  +
Sbjct: 3   KLKNGQEIPKLALGTYEAKG------DQLFAAVDEALKVGYRSFDTAKYYENEKDLGLAL 56

Query: 275 AEAIANGLVTREELFVTTKL--WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 448
              +    +  E++++T+K+  ++ K+A + +   + ESL+ L   Y+DL L+H+P    
Sbjct: 57  KTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLD 116

Query: 449 PDDSPDNIDYL--ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 622
            +D  +N      +TW  ++     G  RSIGVSN+    I  + S   I P +NQIE +
Sbjct: 117 TEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYH 176

Query: 623 PTNTQEPLVAHCQSLGIAVMAYSP 694
           P   ++ L A+C    I   A+SP
Sbjct: 177 PHFQRKVLRAYCNKNEILFQAFSP 200


>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 301

 Score =  105 bits (251), Expect = 1e-21
 Identities = 82/235 (34%), Positives = 113/235 (48%), Gaps = 35/235 (14%)
 Frame = +2

Query: 95  QLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 274
           +L+ G  +P V LGT      E      V  AV  A+  GYRHID AA Y +E +VG G 
Sbjct: 8   KLSSGYDMPAVGLGTWLSKPHE------VENAVETALRLGYRHIDAAACYLNENEVGNGW 61

Query: 275 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL---------- 424
            ++   G V R+++F+T+KLWN  H  D V  A+ ++LK L  DY+DLYL          
Sbjct: 62  KKS---G-VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIH 117

Query: 425 ----------IHFPIATK-------PDDSPD------NIDYLETWQGMQDARQLGLARSI 535
                     IH+P+A +       P D         NI   +TW  ++     G  RSI
Sbjct: 118 DLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSI 177

Query: 536 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQS--LGIAVMAYSP 694
           GVSNF   +I  L+  + I P +NQIE +P   Q  L  + +     I  +AYSP
Sbjct: 178 GVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSP 232


>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
           protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
           sapiens "AKR1B1 protein. - Takifugu rubripes
          Length = 330

 Score =  104 bits (250), Expect = 2e-21
 Identities = 54/118 (45%), Positives = 73/118 (61%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P + LN G  +P++ LGT     K    +    +AV  AI AGYRHIDTA VY++E +VG
Sbjct: 3   PSVTLNTGALMPVLGLGTW----KSGKGV--TTEAVKVAIGAGYRHIDTAYVYENETEVG 56

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 439
            G+   I  G+V REELF+ +KLW   H    V  A +++L  L LDY+DLYL+HFP+
Sbjct: 57  AGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPM 114



 Score = 66.5 bits (155), Expect = 6e-10
 Identities = 31/78 (39%), Positives = 50/78 (64%), Gaps = 2/78 (2%)
 Frame = +2

Query: 464 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQ 637
           D   +L+TW+ M++    GLA++IG+SNFN  QI  +++   +  +P  NQIE +P   Q
Sbjct: 158 DGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQ 217

Query: 638 EPLVAHCQSLGIAVMAYS 691
           E L+  C+S GI+V A++
Sbjct: 218 EKLIHFCRSRGISVTAFA 235


>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
           family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
           reductase family - Thermotoga maritima
          Length = 274

 Score =  104 bits (249), Expect = 2e-21
 Identities = 72/205 (35%), Positives = 111/205 (54%), Gaps = 9/205 (4%)
 Frame = +2

Query: 107 GNTIPIVALGT-GRGTAKESDSI--DEVRQAVYWAIEAGYRHIDTAAVY---QDEEQVGQ 268
           G  IP + LGT G G  +  D    +E+ + +  AI+ GY HIDTA  Y     EE +G+
Sbjct: 10  GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69

Query: 269 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 448
            I +        RE+LF+ +K+W     RD ++ +L+ +LK+L  DY+DLYLIH+P    
Sbjct: 70  AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP---- 119

Query: 449 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT 628
              +P+ I   ET   M +  + GL R IGVSNF+   +   +S S    V +Q++ N  
Sbjct: 120 ---NPE-IPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIE 175

Query: 629 N---TQEPLVAHCQSLGIAVMAYSP 694
           +    ++ L+  CQ  G+ ++AYSP
Sbjct: 176 DRDPERDGLLEFCQKNGVTLVAYSP 200


>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
           lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
           Halorubrum lacusprofundi ATCC 49239
          Length = 309

 Score =  104 bits (249), Expect = 2e-21
 Identities = 71/207 (34%), Positives = 111/207 (53%), Gaps = 1/207 (0%)
 Frame = +2

Query: 77  VQAPCIQLNDGNTIPIVALGTGRGTAKESDSI-DEVRQAVYWAIEAGYRHIDTAAVYQDE 253
           V  P   L  G+T+P + LGT    A + D I D VR A    + +GY HIDTA  Y +E
Sbjct: 32  VTIPTQTLPSGDTLPALGLGT---YALDDDQIADSVRAA----LSSGYTHIDTAEGYHNE 84

Query: 254 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 433
           E +G+ +AE        R+++F+T+K+       + ++ + + SL++L  DY+DLYLIH+
Sbjct: 85  EAIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHW 138

Query: 434 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 613
           P       +P  I   E+ Q M +    GL R++GVSNF+A Q++     S +   +NQI
Sbjct: 139 P-------NPA-ISLRESLQAMAELHDRGLVRNVGVSNFSAYQLSCANHISEVPIAVNQI 190

Query: 614 EVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           E +P   +  LV +C      + A +P
Sbjct: 191 EFHPWFQRPNLVDYCHESDTVIEAAAP 217


>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
           Pezizomycotina|Rep: Aldo-keto reductase, putative -
           Aspergillus fumigatus (Sartorya fumigata)
          Length = 283

 Score =  103 bits (248), Expect = 3e-21
 Identities = 64/168 (38%), Positives = 95/168 (56%), Gaps = 3/168 (1%)
 Frame = +2

Query: 200 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 379
           A+EAGYRHIDTA  Y +E++VG    EA+    + R ++FVTTK+ +   + +     L 
Sbjct: 42  ALEAGYRHIDTAQFYGNEKEVG----EALRKCGIPRSDVFVTTKILSPAGSPEATYQKLL 97

Query: 380 ESLKKLG--LDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 553
           ES++K+G    Y+DL+LIH         S  +    E WQ ++   + G  RSIGVSNF 
Sbjct: 98  ESVEKIGGRDGYVDLFLIH-------SSSSGSAGRKELWQALERLLEEGKTRSIGVSNFG 150

Query: 554 ATQITRLVSNSYI-RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
              I  + + + +  P +NQIE++P   Q  + A+C+  GI V AYSP
Sbjct: 151 VKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAYSP 198


>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
           Ostreococcus|Rep: Aldo/keto reductase family proteins -
           Ostreococcus tauri
          Length = 336

 Score =  103 bits (247), Expect = 4e-21
 Identities = 64/201 (31%), Positives = 113/201 (56%), Gaps = 5/201 (2%)
 Frame = +2

Query: 107 GNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 286
           G T+P++A GT R         +  R AV  A+  G++H+DTA+VY +E  VG+ +    
Sbjct: 59  GITMPMLAFGTYRLRG------ETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACH 112

Query: 287 ANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 463
                  E +FVT+K+  ++  + ++   A+    ++LG    DL L+H+P   K  +SP
Sbjct: 113 RE---VSERIFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTP-DLVLVHWPGRDK--ESP 166

Query: 464 DNIDYLE----TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
           D+  + +    TW+ +++A ++G  R+IGVSN+  + +  L+    ++P +NQIE++   
Sbjct: 167 DSERHRDARRWTWRALENALKMGQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARF 226

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  L A C+S+G+ V+ YSP
Sbjct: 227 PQTELRAFCESVGVHVVGYSP 247


>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 293

 Score =  103 bits (247), Expect = 4e-21
 Identities = 67/176 (38%), Positives = 96/176 (54%), Gaps = 3/176 (1%)
 Frame = +2

Query: 176 EVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKH 349
           E +QA+  A + AGYRH+DTA  Y++E   G+ + E      V R ELF TTK++ N+  
Sbjct: 41  ECKQALLNAFDKAGYRHVDTARYYRNEADCGEAVRECS----VPRSELFYTTKVYLNEMG 96

Query: 350 ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLAR 529
              +   A+++SL K GLDY+DL L+H P   K          L++W  + +  Q G  R
Sbjct: 97  GGSKTRLAVEDSLAKAGLDYLDLVLLHAPDGGKK-------FRLDSWDTLTELVQEGKVR 149

Query: 530 SIGVSNFNATQITRLV-SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           S+GVSNF    I  L+ S   + PV NQIE +P   Q+ + A  ++  I V AY P
Sbjct: 150 SLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAASEAHSIIVQAYCP 205


>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
           intestinalis|Rep: Aldo-keto reductase 1a - Ciona
           intestinalis (Transparent sea squirt)
          Length = 584

 Score =  102 bits (245), Expect = 7e-21
 Identities = 74/218 (33%), Positives = 114/218 (52%), Gaps = 14/218 (6%)
 Frame = +2

Query: 80  QAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQ 259
           + P ++LN G  +P + LGT R  +K  +++         A++ GYR +DTA +Y  E++
Sbjct: 256 EIPDVKLNSGYMMPPIGLGTARLFSKTYETVKT-------ALKLGYRMLDTAQIYTGEDK 308

Query: 260 VG-------QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 418
           +        + I  AIA+  V R ELF+ TKL  +   ++  +  ++ESLKKL  DYIDL
Sbjct: 309 INNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDYIDL 368

Query: 419 YLIH-FPIATK--PDDS--PD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 577
            LIH F ++T   PDD+  P+  N  +L  W+ M++ +  GL RSIGVSN     +  LV
Sbjct: 369 LLIHDFYMSTACGPDDTDLPECKNNPFL-AWKTMEEMQAKGLVRSIGVSNIYIEDLQYLV 427

Query: 578 SNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYS 691
             +       Q   +P + +  + A C    I  M YS
Sbjct: 428 KMAKTPISAVQNWFDPLHQEREIRALCAKNNIRFMGYS 465


>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
           Candida parapsilosis|Rep: Conjugated polyketone
           reductase C2 - Candida parapsilosis (Yeast)
          Length = 307

 Score =  102 bits (245), Expect = 7e-21
 Identities = 68/203 (33%), Positives = 111/203 (54%), Gaps = 13/203 (6%)
 Frame = +2

Query: 125 VALGTGRGTAKESDSIDEVRQA----VYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 292
           +ALGTG    K++ +I++V       +   ++ G+RHIDTA  Y  +++VG    EA+  
Sbjct: 21  IALGTGTKW-KQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEVG----EALKR 75

Query: 293 GLVTREELFVTTKL---WNDKHARDQVVP-ALQESLKKLGLDYIDLYLIHFPIATKPDDS 460
             V RE+++VTTK    W    A  +    ++ ++L +LG+DY+DL+LIH P  T     
Sbjct: 76  TDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLIHSPFFTTEQTH 135

Query: 461 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS---YIRPVINQIEVNP-- 625
              ++  + W+ + +A++ G  R IG+SN     + +L + S      PV+NQIE +P  
Sbjct: 136 GYTLE--QAWEALVEAKKAGKVREIGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFL 193

Query: 626 TNTQEPLVAHCQSLGIAVMAYSP 694
            N  + +V  CQ  GI V A+SP
Sbjct: 194 QNQSKNIVRFCQEHGILVEAFSP 216


>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
           Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
           clavatus
          Length = 283

 Score =  102 bits (245), Expect = 7e-21
 Identities = 62/173 (35%), Positives = 98/173 (56%), Gaps = 3/173 (1%)
 Frame = +2

Query: 185 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 364
           Q+   A++AGYR+IDTA  Y +E++VG    EA+    + R ++FVTTK+ +   + +  
Sbjct: 37  QSCLTALQAGYRNIDTAQFYANEQEVG----EALRTSGIPRSDVFVTTKILSPAGSPEAT 92

Query: 365 VPALQESLKKLGLD--YIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 538
              L ES++K+G +  Y+DL+LIH         S  +    E WQ ++   + G  +SIG
Sbjct: 93  YKKLLESVEKIGGENGYVDLFLIH-------SSSSGSAGRKELWQALEKLLEEGKTKSIG 145

Query: 539 VSNFNATQITRLVSNSYI-RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           VSNF    I  + + + +  P +NQIE++P   Q  + A+C+  GI V AYSP
Sbjct: 146 VSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVEAYSP 198


>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
           Filobasidiella neoformans|Rep: Aldo-keto reductase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 293

 Score =  102 bits (244), Expect = 1e-20
 Identities = 75/208 (36%), Positives = 111/208 (53%), Gaps = 7/208 (3%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I+L  GN IP +  G  +  +KE +       AV  AI+ GYRH+DTA  Y +EE VG+ 
Sbjct: 9   IKLASGNLIPRLGFGVYQARSKECED------AVKKAIDTGYRHVDTAQAYHNEENVGR- 61

Query: 272 IAEAIANGLVTREELFVTTKLW--NDKHARDQVVPALQESLKKL---GLD--YIDLYLIH 430
              AI N  V R  +F+T+K    +  ++  +V+  +++SLKK+   G D  YIDL LIH
Sbjct: 62  ---AIRNSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLMLIH 118

Query: 431 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 610
            P     ++   N      W+ +  A++ G  + IGVSNF    +  L       P +NQ
Sbjct: 119 APWG--GEEGRKN-----NWEALTIAQKEGWVKDIGVSNFGIHHLKALPPPV---PAVNQ 168

Query: 611 IEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           IE++P   Q  +V +C+  GIA+ AYSP
Sbjct: 169 IELHPFCQQRDIVKYCEEHGIAIEAYSP 196


>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
           Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 279

 Score =  102 bits (244), Expect = 1e-20
 Identities = 63/185 (34%), Positives = 94/185 (50%)
 Frame = +2

Query: 140 GRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 319
           G GT +  D+ ++  ++V  A+EAGYRHIDTA  Y +E  VG GIA A     V R+++F
Sbjct: 21  GLGTWQNEDA-EQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAAAD----VDRDDIF 75

Query: 320 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 499
           + TK+W    + D V+   +ESL KLG+D +DL  +H+      +  P+     ET    
Sbjct: 76  LATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG---EYEPE-----ETLPAF 127

Query: 500 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAV 679
            +    GL  ++GVSNF    +   +         NQ+E +P   Q  L  H       +
Sbjct: 128 DELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQSELREHAAEQDYEL 187

Query: 680 MAYSP 694
           +AYSP
Sbjct: 188 VAYSP 192


>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
           marismortui|Rep: Oxidoreductase - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 264

 Score =  102 bits (244), Expect = 1e-20
 Identities = 59/174 (33%), Positives = 95/174 (54%)
 Frame = +2

Query: 173 DEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA 352
           D V+++V   +  GY H+DTA  Y++E ++G+ +A+        RE++F+T+K+      
Sbjct: 12  DTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVFLTSKVLPKHLD 65

Query: 353 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARS 532
            + V+ A + SL +LG DY+DLYL+H+P    P  S       ET   M      G  R+
Sbjct: 66  YESVIEACEASLDRLGTDYLDLYLVHWP---NPATS-----IRETMNAMATLHDQGKIRN 117

Query: 533 IGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSP 694
           +GVSNF+A Q+      + +   +NQIE +P NTQ+ +V  C+     V A +P
Sbjct: 118 VGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAP 171


>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 320

 Score =  101 bits (242), Expect = 2e-20
 Identities = 62/177 (35%), Positives = 99/177 (55%)
 Frame = +2

Query: 86  PCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 265
           P ++L  G  +P +A GTG      SD+  +V  A    +++G+R ID A VY +E  +G
Sbjct: 4   PTVRLASGLELPRLAFGTGTALYN-SDAAKQVTMA----LDSGFRFIDGAEVYANEASMG 58

Query: 266 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 445
            GI   +A+  + R +++V TK+   K     +  A++  L+KL +D +D YL+H P   
Sbjct: 59  AGIESFLASSGLKRNDIYVLTKV--GKEGMKDLQSAIKVELQKLKVDQLDSYLLHLPPRG 116

Query: 446 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 616
           + D  P N+D    W+ ++  +Q GL +SIGVSN+ A+ I +L+      P INQIE
Sbjct: 117 Q-DGLPSNVD---AWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQIE 169


>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 282

 Score =  100 bits (240), Expect = 3e-20
 Identities = 70/201 (34%), Positives = 107/201 (53%)
 Frame = +2

Query: 92  IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 271
           I LN+G TIP V LGT      E D   + + AV +A++  Y  IDTA VY +E  VG+G
Sbjct: 4   ITLNNGITIPQVGLGT---YLLEPD---DAQSAVTYALDNDYTLIDTANVYVNERAVGRG 57

Query: 272 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 451
           +  +       R+E+F+ TKLW     R     A++E+L++LG DYIDL ++H P     
Sbjct: 58  MRASSK----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG--- 107

Query: 452 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 631
                  D +  ++ ++ A + G  R+IG+SNF+  Q  R++    + P INQ+E +P  
Sbjct: 108 -------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECHPYF 160

Query: 632 TQEPLVAHCQSLGIAVMAYSP 694
            Q  L A  +   I + A+ P
Sbjct: 161 PQTELKALLKDHNITLQAWYP 181


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 733,383,200
Number of Sequences: 1657284
Number of extensions: 14830872
Number of successful extensions: 45750
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 43192
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 44852
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54958682807
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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