BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= an--0070 (638 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; ... 303 2e-81 UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n... 290 2e-77 UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=1... 278 7e-74 UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-... 222 5e-57 UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; ... 208 9e-53 UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein;... 205 8e-52 UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aco... 201 1e-50 UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, p... 190 3e-47 UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome... 189 4e-47 UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Gia... 180 2e-44 UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, th... 176 4e-43 UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vit... 173 2e-42 UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea... 167 3e-40 UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermopr... 166 5e-40 UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermopr... 163 4e-39 UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarch... 160 3e-38 UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Haloba... 153 3e-36 UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermopl... 146 5e-34 UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep:... 144 1e-33 UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyru... 144 1e-33 UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; ... 143 4e-33 UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit;... 142 5e-33 UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; ... 140 3e-32 UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; M... 140 3e-32 UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Euk... 136 3e-31 UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanoc... 136 6e-31 UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-... 136 6e-31 UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6;... 135 1e-30 UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intest... 134 1e-30 UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; ... 133 4e-30 UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthe... 133 4e-30 UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharo... 133 4e-30 UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; E... 132 5e-30 UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; E... 132 7e-30 UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; E... 129 5e-29 UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115;... 128 1e-28 UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, wh... 126 6e-28 UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113;... 125 8e-28 UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4;... 124 2e-27 UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Tri... 122 7e-27 UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cry... 122 1e-26 UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; ... 121 1e-26 UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Bas... 120 3e-26 UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n... 118 9e-26 UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pez... 118 9e-26 UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Try... 116 6e-25 UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; O... 116 6e-25 UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putati... 114 2e-24 UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome... 113 3e-24 UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n... 113 3e-24 UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryot... 113 4e-24 UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; ... 111 1e-23 UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fun... 108 1e-22 UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsp... 107 2e-22 UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; B... 107 3e-22 UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15... 106 5e-22 UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of str... 105 9e-22 UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sop... 104 2e-21 UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; ... 104 2e-21 UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; ... 104 2e-21 UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Euk... 103 3e-21 UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family pro... 103 3e-21 UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, th... 102 8e-21 UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putati... 101 1e-20 UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; ... 100 3e-20 UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Euk... 100 3e-20 UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; E... 99 4e-20 UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intes... 99 4e-20 UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp... 99 1e-19 UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cry... 97 4e-19 UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, th... 97 4e-19 UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; En... 96 7e-19 UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomyc... 95 2e-18 UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intes... 91 2e-17 UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fu... 91 2e-17 UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, w... 88 1e-16 UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pe... 88 2e-16 UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; E... 87 3e-16 UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putativ... 86 6e-16 UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Ano... 86 6e-16 UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharom... 85 1e-15 UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, wh... 85 1e-15 UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; B... 83 4e-15 UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Ory... 81 2e-14 UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Tr... 80 4e-14 UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ost... 79 7e-14 UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; C... 79 7e-14 UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intest... 76 8e-13 UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encep... 75 1e-12 UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type fam... 75 2e-12 UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=... 74 3e-12 UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ost... 73 8e-12 UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia thet... 72 1e-11 UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptos... 72 1e-11 UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n... 72 1e-11 UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encep... 71 3e-11 UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia t... 69 1e-10 UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intesti... 68 2e-10 UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putati... 67 3e-10 UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intes... 63 5e-09 UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; T... 62 1e-08 UniRef50_Q9YER0 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 60 4e-08 UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Pir... 60 6e-08 UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, th... 60 6e-08 UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, th... 59 8e-08 UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA... 58 1e-07 UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillard... 57 3e-07 UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum... 57 3e-07 UniRef50_Q8TW10 Cluster: Protease subunit of the proteasome; n=2... 54 4e-06 UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; ... 53 7e-06 UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit;... 53 7e-06 UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfuro... 52 1e-05 UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5... 51 3e-05 UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5; Thermopr... 50 4e-05 UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; ... 50 6e-05 UniRef50_Q9P996 Cluster: Proteasome subunit beta precursor; n=10... 48 1e-04 UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9;... 48 3e-04 UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella ve... 47 3e-04 UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; E... 47 3e-04 UniRef50_Q5KFP2 Cluster: Proteasome subunit beta type; n=3; Fung... 47 4e-04 UniRef50_P28061 Cluster: Proteasome subunit beta precursor; n=4;... 45 0.002 UniRef50_P22141 Cluster: Proteasome component C11; n=36; Ascomyc... 44 0.002 UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia t... 44 0.004 UniRef50_A6R393 Cluster: Proteasome component C5; n=5; Ascomycot... 43 0.007 UniRef50_Q23FB2 Cluster: Proteasome, putative; n=5; Oligohymenop... 42 0.017 UniRef50_A2BN27 Cluster: Proteasome beta; n=3; Desulfurococcales... 42 0.017 UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; ... 41 0.022 UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5;... 41 0.029 UniRef50_O23370 Cluster: Cell wall protein like; n=15; Magnoliop... 40 0.038 UniRef50_Q966I8 Cluster: Proteasome subunit beta type; n=2; Caen... 40 0.038 UniRef50_UPI0000499449 Cluster: proteasome beta subunit; n=1; En... 40 0.051 UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermopro... 40 0.051 UniRef50_Q8T8V8 Cluster: Proteasome subunit beta type; n=13; Neo... 39 0.088 UniRef50_A2DD57 Cluster: Proteasome subunit beta type; n=1; Tric... 39 0.088 UniRef50_Q7QXH2 Cluster: GLP_14_13300_13022; n=1; Giardia lambli... 38 0.15 UniRef50_P23724 Cluster: Proteasome component C5; n=23; Fungi/Me... 37 0.36 UniRef50_P40306 Cluster: Proteasome subunit beta type-10 precurs... 37 0.47 UniRef50_UPI000023D2A5 Cluster: hypothetical protein FG06803.1; ... 36 0.62 UniRef50_Q1YM98 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82 UniRef50_Q6CA23 Cluster: Yarrowia lipolytica chromosome D of str... 36 0.82 UniRef50_A2F8W4 Cluster: Family T1, proteasome beta subunit, thr... 36 1.1 UniRef50_A2DSN0 Cluster: Cellulosomal scaffoldin anchoring prote... 34 3.3 UniRef50_Q00826 Cluster: Probable proteasome subunit beta type-2... 34 3.3 UniRef50_A4RRA7 Cluster: Proteasome subunit beta type; n=2; Ostr... 33 4.4 UniRef50_Q5CU00 Cluster: Pre3p/proteasome regulatory subunit bet... 33 5.8 UniRef50_A0CW62 Cluster: Proteasome subunit beta type; n=3; Olig... 33 5.8 UniRef50_Q9VNA5 Cluster: Probable proteasome subunit beta type-4... 33 5.8 UniRef50_A0P0V6 Cluster: Putative uncharacterized protein; n=2; ... 33 7.7 UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia... 33 7.7 UniRef50_Q8T8U1 Cluster: Proteasome subunit beta type; n=1; Dros... 33 7.7 UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1... 33 7.7 UniRef50_Q5A9K1 Cluster: Possible intermediate filament protein ... 33 7.7 UniRef50_Q0UWV2 Cluster: Predicted protein; n=4; Pezizomycotina|... 33 7.7 UniRef50_O23717 Cluster: Proteasome subunit beta type-5-A precur... 33 7.7 >UniRef50_Q9PTW9 Cluster: Proteasome subunit alpha type-7; n=24; Bilateria|Rep: Proteasome subunit alpha type-7 - Carassius auratus (Goldfish) Length = 251 Score = 303 bits (745), Expect = 2e-81 Identities = 143/186 (76%), Positives = 161/186 (86%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 M+ARYDRAITVFSPDGHL QVEYAQEAV+KGSTA EKKSVAKLQEERT Sbjct: 1 MAARYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGKDIVVLGVEKKSVAKLQEERT 60 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 VRKIC LD+HV MAFAGLTADARI+INRA++ECQSH+LTVEDPVT+EYITRYIA LKQ+Y Sbjct: 61 VRKICALDEHVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIATLKQRY 120 Query: 440 TQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTA 619 TQSNGRRPFGIS LI GFD+DG+P L+QT+PSG Y+ WKANA GRSAKTVREFLEKNYT Sbjct: 121 TQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTD 180 Query: 620 DEVATE 637 + +A++ Sbjct: 181 EAIASD 186 >UniRef50_Q8TAA3 Cluster: Proteasome subunit alpha type-7-like; n=116; Eukaryota|Rep: Proteasome subunit alpha type-7-like - Homo sapiens (Human) Length = 256 Score = 290 bits (711), Expect = 2e-77 Identities = 142/192 (73%), Positives = 158/192 (82%), Gaps = 6/192 (3%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 M++RYDRAITVFSPDGHL QVEYAQEAV+KGSTA EKKSVAKLQ+ERT Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERT 60 Query: 260 VRKICLLDDHVVMAFA------GLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIA 421 VRKIC LDDHV MAFA GLTADAR++INRA++ECQSHKLTVEDPVT+EYITR+IA Sbjct: 61 VRKICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIA 120 Query: 422 GLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFL 601 LKQKYTQSNGRRPFGIS LI GFD DG L+QT+PSG Y+ WKANA GRSAKTVREFL Sbjct: 121 TLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFL 180 Query: 602 EKNYTADEVATE 637 EKNYT D +A++ Sbjct: 181 EKNYTEDAIASD 192 >UniRef50_Q27575 Cluster: Proteasome subunit alpha type-7-1B; n=16; Drosophila|Rep: Proteasome subunit alpha type-7-1B - Drosophila melanogaster (Fruit fly) Length = 252 Score = 278 bits (682), Expect = 7e-74 Identities = 127/185 (68%), Positives = 153/185 (82%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 M+ RYDRA+T++SPDGHLLQVEYAQEAVR+GST EK+SV LQEER Sbjct: 1 MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERM 60 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 VRKIC+LDDHVVM F+GLTADARIL++RAQ+E QSH+L E P T+EYITRYIA LKQ Y Sbjct: 61 VRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNY 120 Query: 440 TQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTA 619 TQSNGRRPFG+SCL+GGFD DG+PHLFQT+PSGI+YEW+AN TGRS++ VR+++EK+ A Sbjct: 121 TQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKH--A 178 Query: 620 DEVAT 634 DE+ T Sbjct: 179 DEILT 183 >UniRef50_Q10329 Cluster: Probable proteasome subunit alpha type-7; n=3; Ascomycota|Rep: Probable proteasome subunit alpha type-7 - Schizosaccharomyces pombe (Fission yeast) Length = 259 Score = 222 bits (543), Expect = 5e-57 Identities = 102/175 (58%), Positives = 134/175 (76%), Gaps = 1/175 (0%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRA++VFSPDG LLQVEY QEAVR+G+TA E+K+V KLQ +KI Sbjct: 4 YDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKI 63 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 ++D+HV +AFAGL ADARILI++A++E Q+HKL + DPV++EY+TRY+AG++QKYTQS Sbjct: 64 AMVDNHVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSG 123 Query: 452 GRRPFGISCLIGGFDY-DGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RPFG+S LI GFD D +P ++QTEP+GIY WKA A GR++K RE+LEKN+ Sbjct: 124 GVRPFGVSTLIAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNW 178 >UniRef50_Q9NDA2 Cluster: Proteasome subunit alpha type-7; n=13; Eukaryota|Rep: Proteasome subunit alpha type-7 - Trypanosoma brucei brucei Length = 247 Score = 208 bits (508), Expect = 9e-53 Identities = 97/174 (55%), Positives = 126/174 (72%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAITVFSPDGHL QVEYAQEAVRKG A EKKSV KLQ+ RT RKI Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVRKGLCAVGVKGKDSIIFAVEKKSVQKLQDSRTTRKI 62 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 LD+H+ +A AGL+ADAR+++N AQ+ECQ +L+ ED + ++ + RY+A ++Q+ TQS+ Sbjct: 63 YKLDEHIYLASAGLSADARVVVNHAQLECQRFRLSYEDAIDVDLLVRYVARVQQRSTQSS 122 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RP+G+S +IGGF+ +G P L++TEPSG W A A GR+ K V EF+EKNY Sbjct: 123 GSRPYGVSTIIGGFNENGQPQLWKTEPSGTSSAWNAAAIGRNDKVVLEFMEKNY 176 >UniRef50_UPI0000E49FB5 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 266 Score = 205 bits (500), Expect = 8e-52 Identities = 93/112 (83%), Positives = 105/112 (93%) Frame = +2 Query: 221 EKKSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLE 400 EKKSVAKLQEERTVRKIC+LDDHV MAFAGLTADARILINRA+IECQSH+LTVEDPVT+E Sbjct: 19 EKKSVAKLQEERTVRKICVLDDHVCMAFAGLTADARILINRARIECQSHRLTVEDPVTVE 78 Query: 401 YITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWK 556 YITR++A LKQ+YTQSNGRRPFG+S LI GFDYDGSP L+QT+P+G Y+ WK Sbjct: 79 YITRFMAQLKQRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWK 130 Score = 113 bits (272), Expect = 3e-24 Identities = 49/69 (71%), Positives = 60/69 (86%) Frame = +2 Query: 431 QKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 ++YTQSNGRRPFG+S LI GFDYDGSP L+QT+P+G Y+ WKANA GRSAKTVREFLEK+ Sbjct: 130 KRYTQSNGRRPFGLSTLIVGFDYDGSPRLYQTDPAGTYHSWKANAIGRSAKTVREFLEKH 189 Query: 611 YTADEVATE 637 Y+ + V +E Sbjct: 190 YSDEVVESE 198 >UniRef50_Q7RM37 Cluster: Proteasome subunit alpha type; n=7; Aconoidasida|Rep: Proteasome subunit alpha type - Plasmodium yoelii yoelii Length = 278 Score = 201 bits (490), Expect = 1e-50 Identities = 93/174 (53%), Positives = 122/174 (70%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAITVFSPDGHLLQVE+A EAV+KG A EKK++ KLQ RT K+ Sbjct: 40 YDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPRTTEKL 99 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 LD+H +AF+GL ADARIL+N+ ++ECQ + L ++ P ++YI +Y+A ++QK+T Sbjct: 100 VKLDEHTCLAFSGLNADARILVNKTRLECQRYYLNMDQPAPVDYIAKYVARIQQKFTHRG 159 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RPFGI+ LI GF + ++QTEPSGIY WKA A G++AK V+EFLEKNY Sbjct: 160 GVRPFGIATLITGFKNNKEICIYQTEPSGIYASWKAQAIGKNAKVVQEFLEKNY 213 >UniRef50_Q23TC6 Cluster: Proteasome subunit alpha type 7-like, putative; n=5; Oligohymenophorea|Rep: Proteasome subunit alpha type 7-like, putative - Tetrahymena thermophila SB210 Length = 242 Score = 190 bits (462), Expect = 3e-47 Identities = 95/182 (52%), Positives = 116/182 (63%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD AITVF G+L QVEYA AV +G + EK LQE RT+RK+ Sbjct: 3 YDTAITVFGKIGNLFQVEYAMAAVNQGLCSIGIRGTDCIVMGVEKNPTTILQETRTIRKV 62 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 LDD + ++GLT DARIL N A++ECQS+ L +D V + YI RYIA ++QKYTQ + Sbjct: 63 QRLDDATCICYSGLTPDARILTNIAKVECQSYSLNYDDRVPINYIARYIASVQQKYTQKS 122 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVA 631 G RPFGIS L+GGFD G P LFQT+PSG EWKA A G+ KTV E LEKNY + +A Sbjct: 123 GARPFGISTLVGGFDSKGQPRLFQTDPSGACTEWKAVALGKHRKTVMENLEKNYQEEYLA 182 Query: 632 TE 637 E Sbjct: 183 EE 184 >UniRef50_UPI0000D9E814 Cluster: PREDICTED: similar to proteasome (prosome, macropain) subunit, alpha type, 8 isoform 2; n=1; Macaca mulatta|Rep: PREDICTED: similar to proteasome (prosome, macropain) subunit, alpha type, 8 isoform 2 - Macaca mulatta Length = 261 Score = 189 bits (461), Expect = 4e-47 Identities = 91/118 (77%), Positives = 101/118 (85%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 M++RYDRAITVFSPDGHL QVEYAQEAV+KGSTA EKKSVAKLQ+ERT Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERT 60 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 VRKIC LDDHV MAFAGLTADAR++INRA++ECQSHKLTVEDPVT+EYITR+IA LKQ Sbjct: 61 VRKICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQ 118 >UniRef50_Q7QXH1 Cluster: Proteasome subunit alpha type; n=2; Giardia intestinalis|Rep: Proteasome subunit alpha type - Giardia lamblia ATCC 50803 Length = 214 Score = 180 bits (439), Expect = 2e-44 Identities = 83/182 (45%), Positives = 122/182 (67%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 MS +YD ++TVFSPDGHL+QVE+A +AV +G++A E+K A+LQ+ R Sbjct: 1 MSGKYDSSLTVFSPDGHLIQVEHAHKAVERGTSAVAVRSAAGIVLAIERKQTARLQDPRA 60 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 +KI +DDH++ FAGLTADAR+LI+RA++ECQ++++T + ++E I + +A + Q + Sbjct: 61 SQKIFDVDDHIIATFAGLTADARVLIDRARLECQAYRMTYDVAPSVEIIAKAVASILQSH 120 Query: 440 TQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTA 619 T G RPFG+S ++ G D +GS H+F +PSG+Y EWKA A G T+ EFLEK Sbjct: 121 THRGGTRPFGVSIILAGNDLNGS-HVFMCDPSGVYTEWKALAIGNQCVTIIEFLEKKLKE 179 Query: 620 DE 625 E Sbjct: 180 GE 181 >UniRef50_A2E5C0 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=2; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 238 Score = 176 bits (428), Expect = 4e-43 Identities = 83/174 (47%), Positives = 111/174 (63%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRA+T FS DG L Q+EYA A G+T EK+ + KLQ++ + + Sbjct: 3 YDRALTRFSSDGRLFQIEYAAAAAHNGTTVLAIQAPGIIVAAIEKRDMMKLQKQDSSNNM 62 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 CLLD H++ AF GL ADAR+L+ +AQ E QS++LT ED + +E I RYIA ++ YTQS Sbjct: 63 CLLDKHILCAFTGLPADARVLVEKAQFEAQSYRLTFEDAIPIENIARYIATVQLTYTQSG 122 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RPFG++ LI GFD PH+++T PSGI EWKA GR V+E++EK Y Sbjct: 123 GVRPFGVTTLICGFDPLDKPHIYETLPSGILSEWKARGIGRFGHPVQEYIEKYY 176 >UniRef50_A5BFH7 Cluster: Proteasome subunit alpha type; n=1; Vitis vinifera|Rep: Proteasome subunit alpha type - Vitis vinifera (Grape) Length = 219 Score = 173 bits (422), Expect = 2e-42 Identities = 85/117 (72%), Positives = 94/117 (80%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 ARYDRAITVFSPDGHL QVEYA EAVRKG+ A EKKS AKLQ+ RTVR Sbjct: 2 ARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGTDTIVLGVEKKSTAKLQDSRTVR 61 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 KI LDDH+ +A AGL ADAR+LINRA+IECQSH+LTVEDPVT+EYITRYIAGL+QK Sbjct: 62 KIVNLDDHIALACAGLKADARVLINRARIECQSHRLTVEDPVTVEYITRYIAGLQQK 118 >UniRef50_Q60177 Cluster: Proteasome subunit alpha; n=29; Archaea|Rep: Proteasome subunit alpha - Methanococcus jannaschii Length = 261 Score = 167 bits (405), Expect = 3e-40 Identities = 83/177 (46%), Positives = 113/177 (63%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAITVFSP+G L QVEYA+EAVR+G+TA +++ +KL + R++ KI Sbjct: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +DDHV A +GL ADAR+LI+RA++E Q ++LT + +++E + + I +KQ YTQ Sbjct: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG+S LI G D LF+T+PSG E+KA A G V E LEK Y D Sbjct: 129 GVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDD 184 >UniRef50_Q4JB24 Cluster: Proteasome subunit alpha; n=6; Thermoprotei|Rep: Proteasome subunit alpha - Sulfolobus acidocaldarius Length = 242 Score = 166 bits (403), Expect = 5e-40 Identities = 79/177 (44%), Positives = 110/177 (62%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAIT+FSPDG L QV+YA EAV++G T EK+ +L + + KI Sbjct: 10 YDRAITIFSPDGSLYQVDYAFEAVKRGWTTLGVKTKSGVVLLAEKRKATQLLDVDGIEKI 69 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +LDDHV FAGL +D RILI+ A+ + H+L ++P+++EY+T+ I+ +KQ YTQ Sbjct: 70 FMLDDHVGCTFAGLASDGRILIDYARSQALQHRLIYDEPISIEYLTKVISDVKQAYTQHG 129 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG++ ++GG D P L TEPSG + + A A G+ T E+LEKNY D Sbjct: 130 GVRPFGVALIVGGIDKGKQPKLLMTEPSGQFMPYYAVAIGQGGYTATEYLEKNYKED 186 >UniRef50_Q8ZVM1 Cluster: Proteasome subunit alpha; n=7; Thermoprotei|Rep: Proteasome subunit alpha - Pyrobaculum aerophilum Length = 243 Score = 163 bits (395), Expect = 4e-39 Identities = 79/179 (44%), Positives = 115/179 (64%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 A YDRAIT+FSP+G + QVEYA EAV++G EK+ ++ L + ++ Sbjct: 7 AGYDRAITIFSPEGKIYQVEYAGEAVKRGWPTVGVKCKAGVVLTAEKRKISALFDSSSLE 66 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI L+D+HV + +GL ADARILI+ A+ SH+ ++P+ +E++T+ + LKQ+YTQ Sbjct: 67 KIYLIDEHVAASPSGLLADARILIDYARDVALSHRFIYDEPIDVEFLTKAVCNLKQQYTQ 126 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG++ LI G D G+ L+QT+PSG+Y + A A G + T+ EFLEKNY D Sbjct: 127 FGGARPFGVALLIAGVDRHGA-RLYQTDPSGVYIGYFATAIGAESGTITEFLEKNYKFD 184 >UniRef50_Q6M0L9 Cluster: Proteasome subunit alpha; n=8; Euryarchaeota|Rep: Proteasome subunit alpha - Methanococcus maripaludis Length = 259 Score = 160 bits (388), Expect = 3e-38 Identities = 80/190 (42%), Positives = 118/190 (62%) Frame = +2 Query: 68 QFLTMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQ 247 Q + ++ YDRAIT+FSP+G L QVEYA+EAVR+G+TA +++ +KL Sbjct: 2 QQMVPASGYDRAITIFSPEGRLYQVEYAREAVRRGTTAVGIKCKDGVVLAVDRRITSKLI 61 Query: 248 EERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGL 427 + ++ KI +DDH+V A +GL ADAR+LI+RA+IE Q ++++ + +T+E + + I + Sbjct: 62 DVSSIEKIFQIDDHIVAATSGLVADARVLIDRARIEAQMNRVSYGEAITVEALAKKICDI 121 Query: 428 KQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 KQ YTQ G RPFG++ LI G D S LF+T+PSG E+KA A G E LE Sbjct: 122 KQAYTQHGGARPFGLALLITGIDRH-SARLFETDPSGALIEYKATAIGSGRPIAMEVLES 180 Query: 608 NYTADEVATE 637 Y + +E Sbjct: 181 KYDENMTVSE 190 >UniRef50_Q5V2X8 Cluster: Proteasome subunit alpha 1; n=8; Halobacteriaceae|Rep: Proteasome subunit alpha 1 - Haloarcula marismortui (Halobacterium marismortui) Length = 260 Score = 153 bits (372), Expect = 3e-36 Identities = 77/174 (44%), Positives = 110/174 (63%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDR IT+FSPDG L QVEYA+EAV++G+ + +K+ + L E +V KI Sbjct: 10 YDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTSDGVVLAVDKRIRSPLMERSSVEKI 69 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 DDH+ +A AG ADAR LI+ A+ + Q ++L +PV +E +T+ I Q+YTQ Sbjct: 70 HKADDHIGIASAGHVADARQLIDFARRQAQVNQLRYGEPVGVETLTKEITDYIQQYTQVG 129 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RPFG++ +IGG +G P LF+T+PSG YEWKA A G +R++LE++Y Sbjct: 130 GARPFGVALIIGGI-VNGEPRLFETDPSGTPYEWKALAVGADRGDIRDYLEEHY 182 >UniRef50_Q6L0W3 Cluster: Proteasome subunit alpha; n=4; Thermoplasmatales|Rep: Proteasome subunit alpha - Picrophilus torridus Length = 234 Score = 146 bits (353), Expect = 5e-34 Identities = 77/174 (44%), Positives = 104/174 (59%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAITVFSPDG L QVEYA+EAV+KGSTA EKK ++L E+ ++ KI Sbjct: 8 YDRAITVFSPDGRLFQVEYAREAVKKGSTALGIKFKDGVALISEKKVRSRLVEKTSLEKI 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 L+DD V +GL ADAR+LI+ A+I Q K+T + +E + + +A Q+YTQ Sbjct: 68 QLIDDRVAAVTSGLVADARVLIDFARISDQQEKVTYGSLMNIENLVKRVADQMQQYTQYG 127 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RP+G+S + G D G P LF +P+G E+K + G V +LEK Y Sbjct: 128 GVRPYGVSIIFAGLDSIG-PRLFDCDPAGTINEYKCVSIGAGKDQVTAYLEKEY 180 >UniRef50_Q74M45 Cluster: NEQ521; n=1; Nanoarchaeum equitans|Rep: NEQ521 - Nanoarchaeum equitans Length = 250 Score = 144 bits (350), Expect = 1e-33 Identities = 70/174 (40%), Positives = 103/174 (59%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRA T+FSPDG LLQVEYA+ V++ TA +KK V K ++ K+ Sbjct: 12 YDRASTLFSPDGRLLQVEYARTTVKQSPTAIGMLYKTGVLVIGDKKIVEKFVIPSSIEKV 71 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 ++DDHV+ A AG+ D R+LI RA++ Q++K P+ + + + IA +KQ+YTQ Sbjct: 72 YIVDDHVIAAPAGIIGDGRVLIERARVIAQTYKYFYGHPIDIRGLVKEIADIKQEYTQIG 131 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RPFG+S + G D D H+F TEP G+++E+K G + V ++L K Y Sbjct: 132 GVRPFGVSIIFAGID-DTGKHIFVTEPGGMFWEYKLAVIGEGEQKVLDYLGKEY 184 >UniRef50_Q9YC01 Cluster: Proteasome subunit alpha; n=1; Aeropyrum pernix|Rep: Proteasome subunit alpha - Aeropyrum pernix Length = 258 Score = 144 bits (350), Expect = 1e-33 Identities = 69/177 (38%), Positives = 105/177 (59%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRA T+FSP+G L QV YA EAV+KG T+ EK+ + L + + KI Sbjct: 12 YDRAATIFSPEGDLYQVRYAFEAVKKGWTSLGIKTNEGVVIAAEKRFIGPLVDIDDIDKI 71 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +DDH+ +AFAG+ D RILI+ A++ H+L +P +E + + +A +KQ YTQ Sbjct: 72 YKIDDHIGVAFAGMGGDGRILIDYARVFTVRHRLLYGEPPPVELVAKVVADVKQAYTQHG 131 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG++ + G + DG+ +++T+P G Y+ +KA A G + E EK+Y +D Sbjct: 132 GVRPFGVALIFAGVNPDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEMFEKHYRSD 188 >UniRef50_P40301 Cluster: Proteasome subunit alpha type-2; n=48; Eukaryota|Rep: Proteasome subunit alpha type-2 - Drosophila melanogaster (Fruit fly) Length = 234 Score = 143 bits (346), Expect = 4e-33 Identities = 68/178 (38%), Positives = 111/178 (62%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 RY ++T FSP G L+Q+EYA AV G+ + E K + L E+ +V + Sbjct: 5 RYSFSLTTFSPSGKLVQLEYALAAVSGGAPSVGIIASNGVVIATENKHKSPLYEQHSVHR 64 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 + ++ +H+ M ++G+ D R+L+ +A+ Q++ LT ++P+ + + + +A L Q+YTQS Sbjct: 65 VEMIYNHIGMVYSGMGPDYRLLVKQARKIAQTYYLTYKEPIPVSQLVQRVATLMQEYTQS 124 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG+S LI G+D D P+L+Q++PSG Y+ WKA A G++A + FLEK Y+ D Sbjct: 125 GGVRPFGVSLLICGWDND-RPYLYQSDPSGAYFAWKATAMGKNAVNGKTFLEKRYSED 181 >UniRef50_A0RWA6 Cluster: 20S proteasome, alpha and beta subunit; n=4; Thermoprotei|Rep: 20S proteasome, alpha and beta subunit - Cenarchaeum symbiosum Length = 245 Score = 142 bits (345), Expect = 5e-33 Identities = 75/174 (43%), Positives = 106/174 (60%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAITVFSPDG L QVEYA E VR+G+ A E+K +LQ T++KI Sbjct: 8 YDRAITVFSPDGRLYQVEYAIETVRRGTIAVGVKSTGGIVIAVEEKP-RRLQISDTIQKI 66 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +DDH+ +A AG DAR + A+ QS+++ ++ V +E + +++A Q++TQ Sbjct: 67 FQVDDHLGVAAAGYIPDARSQVENARFFSQSNRMMYDESVEVEAVAKHLADQCQQFTQYA 126 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RPFG++ +IGG D G LF T+PSG Y + A A G ++ V EFLEK+Y Sbjct: 127 GVRPFGVALIIGGVDDGGKGQLFLTDPSGTYISYDAIAIGAGSEQVTEFLEKSY 180 >UniRef50_P25787 Cluster: Proteasome subunit alpha type-2; n=54; Eukaryota|Rep: Proteasome subunit alpha type-2 - Homo sapiens (Human) Length = 234 Score = 140 bits (339), Expect = 3e-32 Identities = 67/177 (37%), Positives = 107/177 (60%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 Y ++T FSP G L+Q+EYA AV G+ + EKK + L +ER+V K+ Sbjct: 6 YSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKV 65 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + H+ + ++G+ D R+L++RA+ Q + L ++P+ + + +A + Q+YTQS Sbjct: 66 EPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSG 125 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG+S LI G++ +G P+LFQ++PSG Y+ WKA A G++ + FLEK Y D Sbjct: 126 GVRPFGVSLLICGWN-EGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNED 181 >UniRef50_O81148 Cluster: Proteasome subunit alpha type-4; n=5; Magnoliophyta|Rep: Proteasome subunit alpha type-4 - Arabidopsis thaliana (Mouse-ear cress) Length = 250 Score = 140 bits (338), Expect = 3e-32 Identities = 71/187 (37%), Positives = 103/187 (55%), Gaps = 1/187 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKL-QEER 256 MS RYD T+FSP+G L QVEYA EA+ +A EKK +KL Q Sbjct: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTST 60 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 + K+ +DDHV A AG+ +DA ILIN A+++ Q + ++P+ +E + + + KQ Sbjct: 61 SAEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQG 120 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 YTQ G RPFG+S L G+D L+ ++PSG Y WKA A G + + + L+++Y Sbjct: 121 YTQFGGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYK 180 Query: 617 ADEVATE 637 D E Sbjct: 181 DDATREE 187 >UniRef50_Q5CQL5 Cluster: Proteasome subunit alpha type; n=9; Eukaryota|Rep: Proteasome subunit alpha type - Cryptosporidium parvum Iowa II Length = 271 Score = 136 bits (330), Expect = 3e-31 Identities = 70/182 (38%), Positives = 104/182 (57%), Gaps = 1/182 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEE-R 256 MS RYD T FSP+G L QVEYA EA+ + +K V+KL ++ + Sbjct: 11 MSRRYDSRTTTFSPEGRLYQVEYALEAINNAAPTVGILCKEGVILGADKAIVSKLLDQGK 70 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 ++ KI +D H++ A AGLTADA ILI +A+I+ Q ++ T + +E + I KQ Sbjct: 71 SLEKIYTIDRHIIAAVAGLTADANILIAQARIDSQRYQYTYGEEQPVEQLVTQICDRKQS 130 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 YTQ G RPFG+S L G+D + L+Q++PSG + WKA A G++ +T L++ + Sbjct: 131 YTQFGGLRPFGVSFLFAGYDKNYGYQLYQSDPSGNFSGWKATAIGQNNQTATSLLKQEWN 190 Query: 617 AD 622 D Sbjct: 191 ED 192 >UniRef50_A2ST52 Cluster: Proteasome alpha subunit; n=1; Methanocorpusculum labreanum Z|Rep: Proteasome alpha subunit - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 272 Score = 136 bits (328), Expect = 6e-31 Identities = 69/177 (38%), Positives = 106/177 (59%), Gaps = 3/177 (1%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDRAIT+FSPDG L QVEYA+EAV++G+TA +K+ ++L E ++ KI Sbjct: 11 YDRAITMFSPDGRLYQVEYAREAVKRGTTAVGIKCKTGVVLLVDKRVNSRLLEPSSIEKI 70 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D+H+ +A +GL DARIL++RA+IE Q ++++ +PV +E + + + Q YT Sbjct: 71 FRIDEHIGVASSGLVGDARILVDRARIEAQINRVSYGEPVDVETLAKKLCDHMQSYTLFG 130 Query: 452 GRRPFGISCLIGGFDYDGSP---HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G RP+G + LI G + + HLF+T+PSG E+ A G V + E+ Y Sbjct: 131 GARPYGTALLIAGAESSPTGTKYHLFETDPSGTLLEYSATGIGIGRPAVIKLFEQEY 187 >UniRef50_Q09682 Cluster: Probable proteasome subunit alpha type-4; n=5; Eukaryota|Rep: Probable proteasome subunit alpha type-4 - Schizosaccharomyces pombe (Fission yeast) Length = 248 Score = 136 bits (328), Expect = 6e-31 Identities = 72/182 (39%), Positives = 102/182 (56%), Gaps = 1/182 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKL-QEER 256 MS YD T+FSP+G L QVEYA EA+ A EKK +KL ++E Sbjct: 1 MSRSYDSRTTIFSPEGRLYQVEYALEAINHAGVALGIVAKDGIVLAAEKKVTSKLLEQEE 60 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 + K+ + D+++ A AGLTADA ILIN A+ Q + T + + E + R + LKQ Sbjct: 61 SAEKLYHIGDNMLCAVAGLTADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQG 120 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 YTQ G RPFG+S L G+D+ LFQ+ PSG Y W+AN+ G ++ +V+ + + Y Sbjct: 121 YTQYGGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYK 180 Query: 617 AD 622 D Sbjct: 181 DD 182 >UniRef50_Q017X9 Cluster: Alpha 2 subunit of 20S proteasome; n=6; Eukaryota|Rep: Alpha 2 subunit of 20S proteasome - Ostreococcus tauri Length = 270 Score = 135 bits (326), Expect = 1e-30 Identities = 65/178 (36%), Positives = 105/178 (58%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 RY ++T FSP G L+Q+++A A+ G+T+ EKK + L + TV+K Sbjct: 40 RYSFSLTTFSPSGELVQIKHALAAISAGATSLGIKAVDGVVLATEKKLPSTLVDASTVKK 99 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I L D + +A++G+ D R+L A+ E Q++ T ++ + + + R A + Q++TQ Sbjct: 100 IATLTDDIGIAYSGMGPDFRVLTRMARKETQTYYRTYKESIPVSQLVRETATVMQEFTQQ 159 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG+S L+ G+D G P L+Q +PSG Y+ WKA+A G++ + FLEK Y+ D Sbjct: 160 GGVRPFGVSLLMAGYDESG-PSLYQVDPSGSYFAWKASAIGKNMVNAKTFLEKRYSDD 216 >UniRef50_Q7QZC5 Cluster: GLP_43_57537_58271; n=3; Giardia intestinalis|Rep: GLP_43_57537_58271 - Giardia lamblia ATCC 50803 Length = 244 Score = 134 bits (325), Expect = 1e-30 Identities = 68/175 (38%), Positives = 101/175 (57%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 +R+D T+FS DG LLQVEYA +AV + +KK +KL +++T Sbjct: 2 SRFDSRTTLFSQDGRLLQVEYAIKAVTIAAPCLAILAQDGIVFVAQKKLPSKLSDQQTSE 61 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI +D H+V A +GLT+DA ILI+ A+ Q ++P+ +E + +YI+ +KQ YT Sbjct: 62 KIYKIDSHIVCAVSGLTSDANILIDEARTYSQKWLAVYDEPIPVEVLVQYISDVKQNYTH 121 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 G RP+G+S L GG+D L+QT+PSG Y W A + G SA + L++N Sbjct: 122 HGGLRPYGVSFLFGGWDAHLGFQLYQTDPSGNYSAWVATSIGGSAPEIASALKQN 176 >UniRef50_A7D1R0 Cluster: Proteasome endopeptidase complex; n=2; Halorubrum lacusprofundi ATCC 49239|Rep: Proteasome endopeptidase complex - Halorubrum lacusprofundi ATCC 49239 Length = 268 Score = 133 bits (321), Expect = 4e-30 Identities = 68/177 (38%), Positives = 102/177 (57%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDR ++FSPDG + QVEYA+EAV +G+ + + + L E ++ K+ Sbjct: 10 YDRGTSLFSPDGRIYQVEYAREAVSRGAPSVGVRTADGVVFVAMSRPSSTLMEAESIEKL 69 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 LDDH+ A AG ADAR LI+ A+ + Q ++L +PV +E +T+++ Q+ TQ Sbjct: 70 HKLDDHLGTASAGHVADARQLIDLARRQSQGNRLRYGEPVGVETLTKFVTDHIQENTQRG 129 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RP+G + LIGG D +G P LF +PSG EWKA G ++ LE+N+T + Sbjct: 130 GTRPYGAALLIGGID-NGEPRLFAADPSGTPNEWKATVIGGGRSDIQGHLEENWTEE 185 >UniRef50_A2BKB7 Cluster: Proteasome alpha subunit; n=1; Hyperthermus butylicus DSM 5456|Rep: Proteasome alpha subunit - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 243 Score = 133 bits (321), Expect = 4e-30 Identities = 68/177 (38%), Positives = 96/177 (54%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YDR+ +FSPDG L QVEYA EA ++G T EKK + L + + K+ Sbjct: 12 YDRSTAMFSPDGRLFQVEYAMEAAKRGWTMVGVRARDGVVIVAEKKKTSPLIDIEQLEKV 71 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 ++D+H+ F G +D R+LI+ A+ +K + + +EY+TR I L Q YTQ Sbjct: 72 YMVDEHIGAGFVGFGSDGRVLIDYARQLAIQYKFIYGEKIPVEYLTRQICDLMQLYTQHG 131 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RPFG++ LI G D D P LF EPSG Y +KA+ G+ E L++ Y D Sbjct: 132 GVRPFGVTLLIVGVD-DSGPKLFVAEPSGQYMSYKAHGLGQGGGQAIEILQREYRDD 187 >UniRef50_P23638 Cluster: Proteasome component Y13; n=3; Saccharomycetaceae|Rep: Proteasome component Y13 - Saccharomyces cerevisiae (Baker's yeast) Length = 258 Score = 133 bits (321), Expect = 4e-30 Identities = 69/181 (38%), Positives = 100/181 (55%), Gaps = 1/181 (0%) Frame = +2 Query: 83 SARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT- 259 S RYD T+FSP+G L QVEYA E++ TA E+K + L E+ T Sbjct: 3 SRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTS 62 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 K+ L+D + +A AGLTADA ILIN A+I Q++ T + + +E + R ++ +KQ Y Sbjct: 63 TEKLYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGY 122 Query: 440 TQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTA 619 TQ G RPFG+S + G+D L+ + PSG Y WKA + G + + L+ +Y Sbjct: 123 TQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKD 182 Query: 620 D 622 D Sbjct: 183 D 183 >UniRef50_Q27562 Cluster: Proteasome subunit alpha type-1; n=6; Eukaryota|Rep: Proteasome subunit alpha type-1 - Dictyostelium discoideum (Slime mold) Length = 248 Score = 132 bits (320), Expect = 5e-30 Identities = 67/182 (36%), Positives = 110/182 (60%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD IT FSP G + Q+EYA EAV++G A K+S ++L + +K Sbjct: 5 QYDSDITTFSPSGRIHQIEYAMEAVKQGGAAVALKSKQFAVLVSLKRSSSELGSYQ--KK 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I ++DDHV +A +GLTADAR+L N + EC ++ E + +E + +A Q +TQ Sbjct: 63 IFVVDDHVGIAISGLTADARMLCNYMRNECSNYNYVYESQMRVERLVTKVADKHQVHTQR 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 628 GRRP+G+ L+ G+D G+ H++QT PSG +Y++K+ + G +++ + +LEK++ + E Sbjct: 123 YGRRPYGVGLLVAGYDQLGA-HIYQTCPSGNFYDYKSISIGSRSQSAKTYLEKHFESFEE 181 Query: 629 AT 634 T Sbjct: 182 CT 183 >UniRef50_P34119 Cluster: Proteasome subunit alpha type-4; n=4; Eukaryota|Rep: Proteasome subunit alpha type-4 - Dictyostelium discoideum (Slime mold) Length = 250 Score = 132 bits (319), Expect = 7e-30 Identities = 70/184 (38%), Positives = 101/184 (54%), Gaps = 3/184 (1%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 M+ RYD+ T+FSP+G + QVEYA A+R EKK+ AKL + T Sbjct: 1 MARRYDQRTTIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSST 60 Query: 260 V--RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 K+ +D+HVV A AG+T+DA ILIN A++ Q ++P+ +E + I KQ Sbjct: 61 SISEKMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQ 120 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANAT-GRSAKTVREFLEKN 610 YTQ G RPFG+S L G+D L+Q++PSG + WKA + G +++ + L N Sbjct: 121 GYTQYGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIGGENSQVAQSVLRSN 180 Query: 611 YTAD 622 Y D Sbjct: 181 YKPD 184 >UniRef50_Q94561 Cluster: Proteasome subunit alpha type-5; n=2; Eukaryota|Rep: Proteasome subunit alpha type-5 - Entamoeba histolytica Length = 247 Score = 129 bits (312), Expect = 5e-29 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 5/186 (2%) Frame = +2 Query: 71 FLTMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQE 250 F+T + D + FS +G L QVEYA EA++ GST EK+ + L Sbjct: 2 FMTKNEN-DHGVNTFSSEGRLFQVEYATEAMKLGSTVIGIQTKEGVVLAVEKRISSPLML 60 Query: 251 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 430 ++ KI +DDH+ A +GLTADAR LI+ A++E Q+H+ ++P+ +E + + I+ L Sbjct: 61 GSSIEKIIEIDDHIGAAVSGLTADARTLIDNARLEAQNHRFMYDEPINVEVVAQAISDLS 120 Query: 431 QKYTQSNGR-----RPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVRE 595 ++ + + + RPFG++ LI G D G P LFQT+PSG++ E+ A ATG + + Sbjct: 121 LRFGEGSRKKKVMSRPFGVALLIAGVDETG-PRLFQTDPSGMFIEFYAKATGAGTEAAQS 179 Query: 596 FLEKNY 613 L + Y Sbjct: 180 ILHEKY 185 >UniRef50_P28066 Cluster: Proteasome subunit alpha type-5; n=115; Eukaryota|Rep: Proteasome subunit alpha type-5 - Homo sapiens (Human) Length = 241 Score = 128 bits (309), Expect = 1e-28 Identities = 68/186 (36%), Positives = 107/186 (57%), Gaps = 5/186 (2%) Frame = +2 Query: 71 FLTMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQE 250 FLT S YDR + FSP+G L QVEYA EA++ GSTA EK+ + L E Sbjct: 2 FLTRS-EYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME 60 Query: 251 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 430 ++ KI +D H+ A +GL ADA+ LI++A++E Q+H T + +T+E +T+ ++ L Sbjct: 61 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA 120 Query: 431 QKYTQSNG-----RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVRE 595 ++ + + RPFG++ L GG D G P LF +PSG + + A A G +++ + Sbjct: 121 LQFGEEDADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQS 179 Query: 596 FLEKNY 613 L++ Y Sbjct: 180 SLQEVY 185 >UniRef50_A0CZU2 Cluster: Chromosome undetermined scaffold_32, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_32, whole genome shotgun sequence - Paramecium tetraurelia Length = 249 Score = 126 bits (303), Expect = 6e-28 Identities = 68/179 (37%), Positives = 95/179 (53%), Gaps = 1/179 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEE-R 256 MS RYD+ F+PDG L QVEYA EA+ + +A EK+ V+ L E + Sbjct: 1 MSRRYDQKTNTFTPDGRLKQVEYAIEAINQTGSALGVLTNEGMILATEKQEVSHLLEHSK 60 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 KI +D H+ +G TADA ILIN A+ +H+ +D + LE + I KQ Sbjct: 61 HSEKIYPIDRHIFSVVSGHTADANILINYAREAAANHRYQFQDNIALEQLIINICDYKQN 120 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 TQ G+RPFG + L G+D LF T+PSG Y WKA A G++ +L+++Y Sbjct: 121 KTQVGGQRPFGTAFLFAGYDKKNGFQLFSTDPSGNYAGWKATAIGKNNLAANSYLKQDY 179 >UniRef50_P25789 Cluster: Proteasome subunit alpha type-4; n=113; Eukaryota|Rep: Proteasome subunit alpha type-4 - Homo sapiens (Human) Length = 261 Score = 125 bits (302), Expect = 8e-28 Identities = 64/184 (34%), Positives = 100/184 (54%), Gaps = 1/184 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 MS RYD T+FSP+G L QVEYA EA+ T E++++ KL +E Sbjct: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60 Query: 260 V-RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 KI L++ + + AG+T+DA +L N ++ Q + L ++P+ E + + +KQ Sbjct: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 YTQ G+RPFG+S L G+D L+Q++PSG Y WKA G ++ L+++Y Sbjct: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180 Query: 617 ADEV 628 E+ Sbjct: 181 EGEM 184 >UniRef50_P34066 Cluster: Proteasome subunit alpha type-1-A; n=4; core eudicotyledons|Rep: Proteasome subunit alpha type-1-A - Arabidopsis thaliana (Mouse-ear cress) Length = 278 Score = 124 bits (298), Expect = 2e-27 Identities = 64/175 (36%), Positives = 100/175 (57%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD +T +SP G L QVEYA EAV++GS A K+ ++L + RK Sbjct: 5 QYDTDVTTWSPTGRLFQVEYAMEAVKQGSAAIGLRSRSHVVLACVNKAQSELSSHQ--RK 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I +DDH+ +A AGLTAD R+L + E +H T E P+ + + ++A Q TQ Sbjct: 63 IFKVDDHIGVAIAGLTADGRVLSRYMRSESINHSFTYESPLPVGRLVVHLADKAQVCTQR 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 + +RP+G+ L+GG D G+ HL+ PSG Y+E++A A G ++ + +LE+ + Sbjct: 123 SWKRPYGVGLLVGGLDESGA-HLYYNCPSGNYFEYQAFAIGSRSQAAKTYLERRF 176 >UniRef50_A2FCM7 Cluster: Proteasome subunit alpha type; n=2; Trichomonas vaginalis|Rep: Proteasome subunit alpha type - Trichomonas vaginalis G3 Length = 251 Score = 122 bits (294), Expect = 7e-27 Identities = 64/183 (34%), Positives = 100/183 (54%), Gaps = 7/183 (3%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 + YDR + FSPDG LLQVEYA EAV+ GS+A EK+ ++L +V Sbjct: 6 SEYDRNVNTFSPDGRLLQVEYAIEAVKLGSSAVAILCPEGVIFAVEKRLSSQLLIASSVE 65 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGL------ 427 K+ +DDHV + AGL AD R ++ ++E Q+H+ + ++P+ ++ +T+ + L Sbjct: 66 KVYAIDDHVGVVMAGLAADGRTMVEHMRVEAQNHRFSFDEPIGIKAVTQSVCDLALAFGE 125 Query: 428 -KQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 604 ++K RPFG + L+ G + +G HLF T+PSG Y E +A A G ++ L Sbjct: 126 GRRKKGDGQMSRPFGTALLVAGIE-NGKCHLFHTDPSGTYTECRARAIGGGSEGAEALLR 184 Query: 605 KNY 613 Y Sbjct: 185 DLY 187 >UniRef50_Q5CTQ7 Cluster: Proteasome subunit alpha type; n=3; Cryptosporidium|Rep: Proteasome subunit alpha type - Cryptosporidium parvum Iowa II Length = 288 Score = 122 bits (293), Expect = 1e-26 Identities = 59/175 (33%), Positives = 101/175 (57%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD + +SP G + Q+EYA EAV++G+ K+S ++L + +K Sbjct: 34 QYDTDVVTWSPQGRVFQIEYAMEAVKQGTAVVGARNDEIVVLACIKRSTSRLAGYQ--KK 91 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 + +D+H+ +A +G+TADA+++ N + EC ++ T + P+ L + + Q TQ Sbjct: 92 LYKIDNHIGVAVSGITADAKVICNYLRSECLNYSFTYDSPIPLNTLVNRLVLKSQVNTQE 151 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 GRRPFG+ L+ GFD G PHLF+T PSG +E+ + A G ++ + +LEK++ Sbjct: 152 YGRRPFGVGLLLAGFDESG-PHLFETCPSGNCFEYYSIAIGSRSQASKTYLEKHF 205 >UniRef50_P25786 Cluster: Proteasome subunit alpha type-1; n=77; Fungi/Metazoa group|Rep: Proteasome subunit alpha type-1 - Homo sapiens (Human) Length = 263 Score = 121 bits (292), Expect = 1e-26 Identities = 62/174 (35%), Positives = 101/174 (58%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD +TV+SP G + Q+EYA EAV++GS K++ ++L + +K Sbjct: 5 QYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KK 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I +D+H+ ++ AGLTADAR+L N + EC + + P+ + + I Q TQ Sbjct: 63 ILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQR 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 GRRP+G+ LI G+D D PH+FQT PS Y++ +A + G +++ R +LE++ Sbjct: 123 YGRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERH 175 >UniRef50_Q55YJ2 Cluster: Proteasome subunit alpha type; n=3; Basidiomycota|Rep: Proteasome subunit alpha type - Cryptococcus neoformans (Filobasidiella neoformans) Length = 299 Score = 120 bits (289), Expect = 3e-26 Identities = 66/174 (37%), Positives = 98/174 (56%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD T FSP G L QVEYA EAV++GS A K+S +L + +K+ Sbjct: 6 YDSDNTTFSPQGKLFQVEYALEAVKQGSAAIGLRSNTHAVLLTLKRSTGELATYQ--KKL 63 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +DDHV +A AGLT+DAR+L N + + ++T + + + IA Q TQ Sbjct: 64 IRIDDHVGVAIAGLTSDARVLSNYMRQKAMQSRMTYGRATPVARLVQSIADRAQTNTQEY 123 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 GRRP+G+ L+ G D G PHLF+ P+G +E+ A++ G +++ + +LEKNY Sbjct: 124 GRRPYGVGFLVIGKDETG-PHLFEFSPAGTAFEYYAHSIGARSQSAKTYLEKNY 176 >UniRef50_Q4CKY8 Cluster: Proteasome alpha 2 subunit, putative; n=1; Trypanosoma cruzi|Rep: Proteasome alpha 2 subunit, putative - Trypanosoma cruzi Length = 179 Score = 118 bits (285), Expect = 9e-26 Identities = 51/120 (42%), Positives = 80/120 (66%) Frame = +2 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 TV+K+ +LDDHV ++G+ D R+L++ A+ CQ ++LT +P+ + + R I+ L Q+ Sbjct: 7 TVQKVFVLDDHVGCTYSGIGPDCRVLVDAARKACQKYRLTYHEPMPVSQLVRQISSLYQE 66 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 +TQS G RPFG S L+ G D G+ HL+Q +PSG ++ WKA + G+ + + FLEK YT Sbjct: 67 FTQSGGVRPFGCSLLVAGADSQGN-HLYQVDPSGTFWAWKATSIGKGSTDAKTFLEKRYT 125 >UniRef50_Q2GW78 Cluster: Proteasome subunit alpha type; n=4; Pezizomycotina|Rep: Proteasome subunit alpha type - Chaetomium globosum (Soil fungus) Length = 267 Score = 118 bits (285), Expect = 9e-26 Identities = 64/173 (36%), Positives = 94/173 (54%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD FSP G + QVEYA EAV++GS K++ +L + +K+ Sbjct: 6 YDNDSVTFSPQGRIFQVEYAAEAVKQGSVVVGIASKTHVVLVAIKRNAEELSSYQ--KKL 63 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D+HV +A AGLT+DAR+L N + +C H+LT + + + I Q TQ Sbjct: 64 FPIDEHVGIAIAGLTSDARVLSNFMKQQCLGHRLTFGRSMPVRTLVEIIGSKAQINTQHY 123 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 G+RP+G+ L+ G D D PHLF+ +PSG+ E A A G ++ R +LEKN Sbjct: 124 GKRPYGVGLLVAGVD-DHGPHLFEFQPSGMTEEMVAFAIGARSQMARTYLEKN 175 >UniRef50_Q4QFV4 Cluster: Proteasome subunit alpha type; n=7; Trypanosomatidae|Rep: Proteasome subunit alpha type - Leishmania major Length = 285 Score = 116 bits (278), Expect = 6e-25 Identities = 63/185 (34%), Positives = 98/185 (52%), Gaps = 7/185 (3%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 MS RYD T FSP+G L QVEYA EA+++ T EK L + Sbjct: 1 MSHRYDSRTTTFSPEGRLYQVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSEN 60 Query: 260 VR-------KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYI 418 ++ K+ + +H+ + AG+T+DA L+N A++ H+ T ++P+ +E + R + Sbjct: 61 MQDKNISGEKMYKIAEHIGCSVAGVTSDAYALLNYARLSALRHQYTFQEPIAIEDLCRIL 120 Query: 419 AGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREF 598 KQ YTQ G RP+G+S L+ G+D L+ TEPSG Y W A A G++ + Sbjct: 121 CDEKQLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSL 180 Query: 599 LEKNY 613 L+K++ Sbjct: 181 LKKDW 185 >UniRef50_P52428 Cluster: Proteasome subunit alpha type-1; n=4; Oryza sativa|Rep: Proteasome subunit alpha type-1 - Oryza sativa subsp. japonica (Rice) Length = 270 Score = 116 bits (278), Expect = 6e-25 Identities = 60/175 (34%), Positives = 95/175 (54%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD +T +SP G L QVEYA EAV++GS K+ ++L + RK Sbjct: 5 QYDTDVTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASELSSHQ--RK 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 + + DH +A AGLTAD R+L + EC +H + P+ + + +A Q TQ Sbjct: 63 VFRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQR 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 + +RP+G+ L+ G D G+ HL+ PSG Y+E++A A G ++ + FLE+ + Sbjct: 123 SWKRPYGVGLLVAGLDESGA-HLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRF 176 >UniRef50_A5K435 Cluster: Proteosome subunit alpha type 1, putative; n=5; Plasmodium|Rep: Proteosome subunit alpha type 1, putative - Plasmodium vivax Length = 269 Score = 114 bits (274), Expect = 2e-24 Identities = 57/173 (32%), Positives = 99/173 (57%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD +SP+G L QVEYA EA+++G+ A KK ++KL + K+ Sbjct: 6 YDTDNITYSPEGRLYQVEYANEAIKQGTCAVAIKSKDFVVVCGLKKRISKLSFHQ--EKL 63 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +DD++ + +G+T+DA++L + EC SHK ++ + +E + + +A Q+ TQ + Sbjct: 64 FKIDDYIGVTMSGITSDAKVLTKYMRNECLSHKFLFDENMNIEKLVKKVADKYQQNTQRS 123 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 RR FG+ +I G Y P++F+T+P+G Y+E+ A + G + + +LEKN Sbjct: 124 SRRAFGVGLIIAG--YFKEPYIFETKPNGSYFEYIALSFGARSHASKTYLEKN 174 >UniRef50_UPI0000E48E53 Cluster: PREDICTED: similar to Proteasome (prosome macropain) subunit alpha type 4; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Proteasome (prosome macropain) subunit alpha type 4 - Strongylocentrotus purpuratus Length = 257 Score = 113 bits (273), Expect = 3e-24 Identities = 59/179 (32%), Positives = 96/179 (53%), Gaps = 1/179 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 MS RYD T+FSP+G L QVEYA EA+ T+ E+++ KL ++ Sbjct: 1 MSRRYDSKTTIFSPEGRLYQVEYAMEAIGHAGTSLGILASDGVLLAAERRNTHKLLDDVV 60 Query: 260 VR-KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 KI L+ + + +G+T+DA +L + ++ Q + L ++ + E + + +KQ Sbjct: 61 FSDKIYKLNSDMACSVSGITSDANVLTSELRLAGQRYFLQYQENIPNEQLVSTLCDIKQF 120 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 YTQ+ G+RPFG+S L G+D L+Q++PSG Y WKA G ++ L++ Y Sbjct: 121 YTQAGGKRPFGVSILYMGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAISMLKQEY 179 >UniRef50_A7AW04 Cluster: Proteasome alpha 5 subunit, putative; n=1; Babesia bovis|Rep: Proteasome alpha 5 subunit, putative - Babesia bovis Length = 250 Score = 113 bits (273), Expect = 3e-24 Identities = 60/189 (31%), Positives = 97/189 (51%), Gaps = 7/189 (3%) Frame = +2 Query: 77 TMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEER 256 T YDR + FSP+G + QVEYA A++ GSTA E + + L E Sbjct: 3 TARNEYDRGVNTFSPEGRIFQVEYALGAIKLGSTALAIATKEGVIFASEHRVNSPLMESV 62 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 ++ KI +D H+ +GL ADAR LI+ ++EC +H+ +P+ + IA + Sbjct: 63 SLEKIMEIDTHIGCTMSGLIADARTLIDHGRLECANHRFVYNEPLAIRSCVESIADMALD 122 Query: 437 YT-------QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVRE 595 ++ + RPFG++ L+GG D DG P ++ +PSG ++KA+A G + + Sbjct: 123 FSDIFDTRKKKTMSRPFGVALLVGGIDIDG-PSIWCVDPSGTSIKYKASAIGSAQEGAES 181 Query: 596 FLEKNYTAD 622 L++ Y D Sbjct: 182 VLQERYRDD 190 >UniRef50_P21242 Cluster: Proteasome component C1; n=18; Eukaryota|Rep: Proteasome component C1 - Saccharomyces cerevisiae (Baker's yeast) Length = 288 Score = 113 bits (271), Expect = 4e-24 Identities = 62/172 (36%), Positives = 92/172 (53%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + +VFSPDG QVEYA +AV G+T+ EK +KL + KI Sbjct: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 ++D H+ ++GL D R L+NR + E S K + P+ + + Q +T N Sbjct: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG+S + GG D +G+ HL+ EPSG Y+ +K ATG+ ++ + LEK Sbjct: 128 SVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 >UniRef50_O96788 Cluster: Proteasome subunit alpha type-1; n=10; Trypanosomatidae|Rep: Proteasome subunit alpha type-1 - Trypanosoma brucei rhodesiense Length = 266 Score = 111 bits (268), Expect = 1e-23 Identities = 63/176 (35%), Positives = 93/176 (52%), Gaps = 1/176 (0%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKS-VAKLQEERTVR 265 +YD T +SP G L QVEYA EAV GS A K++ V+ L + Sbjct: 5 QYDTDTTTWSPTGRLFQVEYANEAVNNGSAAVGVKGADYVVLTALKRNPVSGLSSYQ--E 62 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 K LD+HV MA +GL AD R L + EC +++ + L + + Q++ Q Sbjct: 63 KAFKLDEHVGMAISGLVADGRALSRFLRTECMNYRYMHDSDAPLVMLADIVGAKHQRHIQ 122 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G+RPFG+ LI G+D G P L+QT PSG +++KA A G ++ R +LE+++ Sbjct: 123 FAGKRPFGVGLLIAGYDRQG-PRLYQTVPSGDVFDFKATAMGLRSQAARTYLERHF 177 >UniRef50_Q4P0X9 Cluster: Proteasome subunit alpha type; n=3; Fungi/Metazoa group|Rep: Proteasome subunit alpha type - Ustilago maydis (Smut fungus) Length = 305 Score = 108 bits (260), Expect = 1e-22 Identities = 59/182 (32%), Positives = 89/182 (48%), Gaps = 1/182 (0%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRK-GSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 YDR +T+FSPDG L QVEYA +A+ G T+ +KK KL + +V Sbjct: 6 YDRYLTIFSPDGRLYQVEYAFKAINTAGLTSIAVRGKDCSVVVGQKKVPDKLIDASSVTN 65 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I L + G ADAR + RA++E K +T + + + +A + Q YTQ Sbjct: 66 IFNLTPEIGCIMTGRVADARAQVQRAKMEAADFKYKYGYAITPDLLAKRMANMNQVYTQR 125 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 628 RP+G+S ++ G D + P +F+ +P+G Y ++A A G FLEK + Sbjct: 126 AAMRPYGVSMILVGIDAERGPQIFKIDPAGYYVGFRATAAGVKQTEATNFLEKQFKKSST 185 Query: 629 AT 634 T Sbjct: 186 TT 187 >UniRef50_Q8SRU3 Cluster: 26S PROTEASOME ZETA CHAIN; n=4; Microsporidia|Rep: 26S PROTEASOME ZETA CHAIN - Encephalitozoon cuniculi Length = 232 Score = 107 bits (258), Expect = 2e-22 Identities = 53/179 (29%), Positives = 98/179 (54%), Gaps = 5/179 (2%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 + +++ +S +G + Q+EYA +A+ G+T EKK ++ LQ ++V K Sbjct: 4 FKQSVNTYSSEGRIHQIEYAMKAMNLGTTTIGVRTKEFVILCSEKKILSTLQNPKSVVKH 63 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + DH+V+ F+G++ D + ++ R++ C SH + +++E + +Y++ L ++ + + Sbjct: 64 YKIYDHIVLGFSGISGDTKTIVKRSRDFCISHTHMYGENISVERLLKYLSSLSLRFGEED 123 Query: 452 G-----RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 RRPFG+S +I GFD + P L+ +PSG Y +KA A G + V LE Y Sbjct: 124 EAKMIFRRPFGVSLIIAGFDTE--PRLYSLDPSGSYISYKAKAIGSGHEVVEGILENEY 180 >UniRef50_A7AV06 Cluster: Proteasome subunit alpha type 1; n=1; Babesia bovis|Rep: Proteasome subunit alpha type 1 - Babesia bovis Length = 257 Score = 107 bits (256), Expect = 3e-22 Identities = 54/173 (31%), Positives = 93/173 (53%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD +SP G L QVEYA EAV++G+ ++ +KL E + K Sbjct: 5 QYDTDCITWSPQGRLFQVEYAMEAVKQGTCCVGIKSQTHIVLCAVRRKSSKLAEYQD--K 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I + +H+ + +G+T+DA++++N + EC ++K +T + IA Q TQ+ Sbjct: 63 IFCIGEHIAVVMSGITSDAKMIVNYMRNECLNNKFLYGCDITATKLVSLIAQKSQANTQT 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 + +RPFG+ L+ G+D HL++T PSG E+ A A G ++ + +LE+ Sbjct: 123 SSKRPFGVGLLVAGYDDRTGLHLYETCPSGNVVEYNATAFGARCQSAKTYLER 175 >UniRef50_O81146 Cluster: Proteasome subunit alpha type-6-A; n=15; Eukaryota|Rep: Proteasome subunit alpha type-6-A - Arabidopsis thaliana (Mouse-ear cress) Length = 246 Score = 106 bits (254), Expect = 5e-22 Identities = 57/175 (32%), Positives = 94/175 (53%), Gaps = 1/175 (0%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRK-GSTAXXXXXXXXXXXXXEKKSVAKLQEERTV 262 A YDR IT+FSP+G L QVEYA +AV+ G T+ +KK KL ++ +V Sbjct: 7 AGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSV 66 Query: 263 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 442 + + ++ + G+TADAR L+ +A+ + + T + ++ + ++IA Q YT Sbjct: 67 THLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYT 126 Query: 443 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 Q RP G+ ++ G D + P L++ +P+G +Y KA + G + FLEK Sbjct: 127 QHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEK 181 >UniRef50_Q6CBM3 Cluster: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica; n=6; Ascomycota|Rep: Yarrowia lipolytica chromosome C of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 289 Score = 105 bits (252), Expect = 9e-22 Identities = 59/174 (33%), Positives = 91/174 (52%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD +SP G L QVEYA EA+++GS K++ +L + +KI Sbjct: 5 YDNDSVTYSPTGRLFQVEYALEAIKQGSAVVGLVSKTHAVVVALKRNAEELGSYQ--KKI 62 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D+H+ +A AGL DAR+L N + + S ++ + P+ + IA Q TQ Sbjct: 63 IKVDNHLGVALAGLAPDARVLSNFLRQQAMSSQMVYKRPLAVSRAVYAIADKAQGNTQQY 122 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 GRRP+G+ LI G D + PHL++ PSG E++ A G ++ R +LEK + Sbjct: 123 GRRPYGVGLLIIGHD-EAGPHLYEFLPSGSALEYRGAAIGARSQAARTYLEKKF 175 >UniRef50_Q9VK14 Cluster: Proteasome subunit alpha type; n=2; Sophophora|Rep: Proteasome subunit alpha type - Drosophila melanogaster (Fruit fly) Length = 289 Score = 104 bits (250), Expect = 2e-21 Identities = 59/180 (32%), Positives = 94/180 (52%), Gaps = 1/180 (0%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTV-R 265 +YD T +SP G L QVEYA EAV++G+ ++ ++ T+ R Sbjct: 5 QYDNDTTTWSPQGRLFQVEYAMEAVKQGAATVGLKGTDYAVLAALCRTS---KDTNTLQR 61 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI +DDHV M+ AGLTADAR++ + EC +++ + + + + Q TQ Sbjct: 62 KIMPVDDHVGMSIAGLTADARVVCQYMRTECMAYRHSYNAEFPVRRLVSNLGNKLQTTTQ 121 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 625 RRP+G+ L+ G+D G PH++Q P+ KA A G +++ R +LE+N + E Sbjct: 122 RYDRRPYGVGLLVAGYDEQG-PHIYQVMPTANVLNCKAMAIGSRSQSARTYLERNMESFE 180 >UniRef50_P60900 Cluster: Proteasome subunit alpha type-6; n=69; Eukaryota|Rep: Proteasome subunit alpha type-6 - Homo sapiens (Human) Length = 246 Score = 104 bits (250), Expect = 2e-21 Identities = 57/176 (32%), Positives = 92/176 (52%), Gaps = 1/176 (0%) Frame = +2 Query: 83 SARYDRAITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERT 259 SA +DR IT+FSP+G L QVEYA +A+ +G T+ +KK KL + T Sbjct: 6 SAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSST 65 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 V + + +++ G+TAD+R + RA+ E + K + ++ + + IA + Q Y Sbjct: 66 VTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVY 125 Query: 440 TQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 TQ+ RP G ++ G D + P +++ +P+G Y +KA A G FLEK Sbjct: 126 TQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEK 181 >UniRef50_O23715 Cluster: Proteasome subunit alpha type-3; n=12; Magnoliophyta|Rep: Proteasome subunit alpha type-3 - Arabidopsis thaliana (Mouse-ear cress) Length = 249 Score = 104 bits (250), Expect = 2e-21 Identities = 58/172 (33%), Positives = 88/172 (51%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD ++T FSPDG + Q+EYA +AV T EK +K+ + R+I Sbjct: 8 YDLSVTTFSPDGRVFQIEYAAKAVDNSGTVVGIKCKDGIVMGVEKLIASKMMLPGSNRRI 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + H MA AGL AD R ++ RA+ E +S++ D V ++ ++ +A T Sbjct: 68 HSVHRHAGMAVAGLAADGRQIVARAKSEARSYESVYGDAVPVKELSERVASYVHLCTLYW 127 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG ++GG+D DG P L+ EPSGI Y + A G+ + + +EK Sbjct: 128 WLRPFGCGVILGGYDRDG-PQLYMIEPSGISYRYFGAAIGKGKQAAKTEIEK 178 >UniRef50_Q0MYX3 Cluster: Proteasome subunit alpha type; n=3; Eukaryota|Rep: Proteasome subunit alpha type - Emiliania huxleyi Length = 264 Score = 103 bits (248), Expect = 3e-21 Identities = 57/181 (31%), Positives = 90/181 (49%), Gaps = 4/181 (2%) Frame = +2 Query: 83 SARYDRAITVFSPDGHLLQVEYAQEAVR-KGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 SA YDR IT+FSP+G L QVEYA +A++ G T+ ++K KL + + Sbjct: 6 SAGYDRHITIFSPEGRLYQVEYAFKAIKTSGLTSVGVRGADPCVVLTQRKVPDKLYDPES 65 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 V + + ++ + G+ DAR + + + E K + + Y+ + A Q Y Sbjct: 66 VTNMYAITPNIGLVMTGIVPDARASVKKLREEAAKFKFNNGYDIPVSYLAKRAADTAQVY 125 Query: 440 TQSNGRRPFGISCLIGGFDYDGS---PHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 TQ RP GI+ +I G D +G P LF+ +P+G Y +KA + G + FLEK Sbjct: 126 TQHANMRPLGIAMIIIGIDVEGEKKVPQLFRCDPAGYYVGYKATSAGAKEQEANNFLEKR 185 Query: 611 Y 613 + Sbjct: 186 F 186 >UniRef50_Q22WB3 Cluster: Proteasome A-type and B-type family protein; n=5; Oligohymenophorea|Rep: Proteasome A-type and B-type family protein - Tetrahymena thermophila SB210 Length = 267 Score = 103 bits (248), Expect = 3e-21 Identities = 59/173 (34%), Positives = 92/173 (53%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + +S +G LLQV+YA +A+ +GS +K+S +KL + KI Sbjct: 23 YDTDCSTWSTNGKLLQVDYATKAIDQGSITIGLRSQKFAVLVAQKRSNSKLSGYQ--EKI 80 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +DD + M AG+TADAR++ + EC +HK + + I+ Q TQ+ Sbjct: 81 FQVDDKIGMGVAGITADARVICKYMRTECLNHKYVYGSQHPAQRLVIKISEKSQHKTQTY 140 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 G+RP+G+ LI + DG P LFQT PSG +YE+ + G ++ + +LE N Sbjct: 141 GKRPYGVGTLIIAQESDG-PKLFQTLPSGDFYEFYGQSIGSRSQAAKTYLENN 192 >UniRef50_A2E1I9 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 233 Score = 102 bits (244), Expect = 8e-21 Identities = 59/175 (33%), Positives = 89/175 (50%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 ++YD T FSP+G +LQVE A +AV++G S ++ + Sbjct: 4 SKYDENATTFSPEGRILQVENAMKAVQQGMPTVGLKSKTHAVIAGVMHSPSEFSSHQP-- 61 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI +D H+ +A +GLTAD R L + EC H + + + +A QK T Sbjct: 62 KIFKIDQHIGVAISGLTADGRGLCKFLRNECLHHTFCFGTEIRVADLADTVALQSQKKTS 121 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 G+RP+G+ L+ G DG P LF+T PSG ++E+ A A GR A+ + +LE N Sbjct: 122 KVGKRPYGVGLLMIGAGVDG-PRLFETCPSGQHWEYNAQAIGRRAQAAKTYLETN 175 >UniRef50_Q4N3Q8 Cluster: Proteasome subunit alpha type 1, putative; n=2; Theileria|Rep: Proteasome subunit alpha type 1, putative - Theileria parva Length = 252 Score = 101 bits (243), Expect = 1e-20 Identities = 51/173 (29%), Positives = 94/173 (54%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD +SP G L QVEYA E+V++G+ K+ ++KL + + K Sbjct: 5 QYDTDCITWSPQGRLFQVEYAMESVKQGTCCVGIKSNTHLVLCALKRKISKLAQVQD--K 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 + + +++ +A +G+T+DA+++I+ + EC S++ +T + ++ Q TQ Sbjct: 63 LYKVGEYIGVAMSGITSDAKMIISYMRNECLSNRFLYGCDITASQLVSLVSEKSQANTQV 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 + +RPFG+ L+ G+D HLF+T PSG E+ A A G ++ + +LE+ Sbjct: 123 SSKRPFGVGLLVAGYDETTGLHLFETCPSGNVVEFNATAFGARCQSAKTYLER 175 >UniRef50_Q27563 Cluster: Proteasome subunit alpha type-3; n=11; Eukaryota|Rep: Proteasome subunit alpha type-3 - Dictyostelium discoideum (Slime mold) Length = 248 Score = 100 bits (240), Expect = 3e-20 Identities = 58/177 (32%), Positives = 90/177 (50%) Frame = +2 Query: 77 TMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEER 256 ++ + YD ++ +SPDG L QV+YA +AV T EK +K+ Sbjct: 3 SVGSGYDLYVSTYSPDGKLFQVDYANKAVENSGTLVAIKAKDGVVLGVEKLVPSKMLCSG 62 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 + R++ +D HV +A AG ADAR LI RA+ E +++K T P+ ++ +++ IA Sbjct: 63 SNRRVHHIDTHVGVAIAGFLADARQLITRARSEAKNYKSTYGQPIPIKVLSQRIASYNHM 122 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 +T RPFG S I G D G P LF EPSG + + G+ + + LE+ Sbjct: 123 HTLYGSVRPFGCSIAITGIDQYG-PQLFLVEPSGSCVGYFGASLGKGKQAAKNELEE 178 >UniRef50_A4UHA5 Cluster: Proteasome subunit alpha type; n=8; Eukaryota|Rep: Proteasome subunit alpha type - Alexandrium fundyense (Dinoflagellate) Length = 254 Score = 100 bits (239), Expect = 3e-20 Identities = 55/175 (31%), Positives = 89/175 (50%), Gaps = 1/175 (0%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 A YD ++T FSPDG + QVEYAQ+AV T EK ++K+ + T + Sbjct: 6 AGYDLSVTTFSPDGRVFQVEYAQKAVENSGTTVAICCKDGVIFAVEKFLLSKMLVQGTNK 65 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 +I + H M+ AG +AD+R ++ RA+ E +K + + + E + + YT Sbjct: 66 RIFPVHRHAGMSIAGFSADSRQIVARARSEAHQYKNSYNEEIPPELLAERLGLFVHAYTL 125 Query: 446 SNGRRPFGISCLIGGFDYD-GSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG S L+G D D P LF +P+G+ +++ A G+ + + +EK Sbjct: 126 YWSIRPFGCSVLLGCVDQDTKKPSLFCVDPAGMVFKYSGTAIGKGKQAAKTEIEK 180 >UniRef50_UPI0000498A1A Cluster: proteasome alpha subunit; n=2; Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha subunit - Entamoeba histolytica HM-1:IMSS Length = 247 Score = 99 bits (238), Expect = 4e-20 Identities = 59/177 (33%), Positives = 89/177 (50%) Frame = +2 Query: 77 TMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEER 256 ++ + YD + T FSPDG + Q++YA +AV +TA EK ++K+ E+ Sbjct: 3 SIGSGYDDSCTTFSPDGKVFQIDYATKAVENSATALSIKCIDGVVFGVEKLIISKMIEKS 62 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 + ++I + HV + AG DAR L+ +A E +S K + ++ + IA Q Sbjct: 63 SNKRIFNVGTHVGITCAGFLPDARKLVKKANEEAESFKENYGMNIPVKVLAEKIAMYMQN 122 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 +T RPFG S LIGG D G L EPSG Y + AN G+ + + LEK Sbjct: 123 HTLYGSLRPFGCSLLIGGVDQHGY-SLHYIEPSGTTYGYFANGIGKGKQICKNELEK 178 >UniRef50_Q7QYA1 Cluster: GLP_387_56144_56881; n=2; Giardia intestinalis|Rep: GLP_387_56144_56881 - Giardia lamblia ATCC 50803 Length = 245 Score = 99 bits (238), Expect = 4e-20 Identities = 56/182 (30%), Positives = 95/182 (52%), Gaps = 2/182 (1%) Frame = +2 Query: 83 SARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTV 262 S +D VFSPDG + Q+EYA ++V TA E+++ + L+ + Sbjct: 3 SNSHDTHANVFSPDGRIFQIEYALKSVTLSPTALAIRTHTGIVFAVERRTSSPLRLQTRF 62 Query: 263 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 442 +I +DDH + AG +D+++L+ A+ E QSH+ ++ V L+ ++ ++ + + Sbjct: 63 ERIMHVDDHAMACVAGHASDSKLLLQSARTEAQSHRFLYDEFVPLQALSESLSEVFINFG 122 Query: 443 QSNGR--RPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 + + RPFG S LIGG D +P LF EPSG E A + G + T ++ L+ +Y Sbjct: 123 RGKKKLGRPFGCSLLIGGLD-GSTPRLFCAEPSGSVTEAMARSLGAGSTTAQQTLQDSYR 181 Query: 617 AD 622 D Sbjct: 182 DD 183 >UniRef50_Q751N3 Cluster: AGL336Wp; n=7; Ascomycota|Rep: AGL336Wp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 306 Score = 98.7 bits (235), Expect = 1e-19 Identities = 56/172 (32%), Positives = 89/172 (51%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD FSP G L QVEYA EA+++GS K++ +L + +KI Sbjct: 79 YDGDTVTFSPTGRLFQVEYALEAIKQGSATVGLRSNKYVVLVALKRNADELSSYQ--KKI 136 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 DDH+ ++ AGL DAR+L N + +C +L +++ + ++ QK TQS Sbjct: 137 IKCDDHMGLSLAGLAPDARVLSNFLRQQCNYSQLVYARDLSVVKAGQLLSDKAQKNTQSY 196 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 G RP+G+ L+ G+D G+ HL + +PSG E A G ++ + +LE+ Sbjct: 197 GGRPYGVGLLLAGYDNSGA-HLLEFQPSGNTLELYGAAIGARSQGAKTYLER 247 >UniRef50_Q5CUM6 Cluster: Proteasome subunit alpha type; n=2; Cryptosporidium|Rep: Proteasome subunit alpha type - Cryptosporidium parvum Iowa II Length = 251 Score = 96.7 bits (230), Expect = 4e-19 Identities = 51/177 (28%), Positives = 86/177 (48%) Frame = +2 Query: 77 TMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEER 256 ++ + YD +++ FSPDG + QVEYA +AV T +K +K+ Sbjct: 3 SVGSGYDSSVSTFSPDGRVFQVEYANKAVDNSGTTIAMIYNSGIVFAVDKYVASKMMVAG 62 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 T R++ +D+ + AG D+ +++ A+ E +++ +P+ + + IA Sbjct: 63 TNRRVFAIDNQIGCCVAGFVTDSNKIVSIARSESLNYQKIYGNPIPIRVLAERIAMYMHN 122 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 +T RPFG S L+GG D D L+ PSG Y++ A A G+ + R LEK Sbjct: 123 FTLYGSVRPFGCSILLGGLDQDRGVELYCIHPSGSCYKYCAMAVGKGRQFARTDLEK 179 >UniRef50_A2FJV7 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 232 Score = 96.7 bits (230), Expect = 4e-19 Identities = 55/177 (31%), Positives = 91/177 (51%) Frame = +2 Query: 95 DRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKIC 274 D ++T FS G L Q+E A +AV G E K + L E+ T K+ Sbjct: 5 DFSLTTFSSGGKLNQIESALKAVSLGGQCVGVKAKNGAVIACESKPSSPLVEKVTNLKVQ 64 Query: 275 LLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNG 454 ++D+V + ++G+ D +++ + + L + + + ++ A Q YTQ G Sbjct: 65 KINDNVGIVYSGVNTDFHVILKSLRKASIKYSLRLGVEMPTREVVKHAAHKMQYYTQIGG 124 Query: 455 RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 625 RPFG+S LI G++ G P L+Q +PSG ++ WKA A G+ + R FLE+ Y+ D+ Sbjct: 125 VRPFGVSLLIIGWEELG-PTLWQVDPSGTFWAWKATALGKRSDGSRTFLERRYSEDQ 180 >UniRef50_Q8SRJ0 Cluster: 26S PROTEASOME SUBUNIT ALPHA-4; n=1; Encephalitozoon cuniculi|Rep: 26S PROTEASOME SUBUNIT ALPHA-4 - Encephalitozoon cuniculi Length = 224 Score = 95.9 bits (228), Expect = 7e-19 Identities = 54/179 (30%), Positives = 93/179 (51%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 ++ + VFSPDG L+QVEYAQ+A +GS E+KS +L E Sbjct: 3 FEEQLAVFSPDGRLIQVEYAQQASEQGSLVVFGVDSEKISVSIERKSGNRLLLEEEKLFP 62 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + M+++G DA +++N A++ C S+K + + + ++ + R ++ KQ+YT Sbjct: 63 ISESQKIWMSYSGFKPDAYLVMNVARMICFSYKNSTGEDIAIDQLARMLSEYKQRYTVVY 122 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 628 +RPFG+ ++ F + P + EP G + E+ A G+ ++ V E+LEK D V Sbjct: 123 HQRPFGVRTVL--FGLEPRPVAYVLEPDGNFSEFFCGAIGQKSQKVCEYLEKGEKGDLV 179 >UniRef50_A6R382 Cluster: Proteasome component C1; n=3; Pezizomycotina|Rep: Proteasome component C1 - Ajellomyces capsulatus NAm1 Length = 426 Score = 94.7 bits (225), Expect = 2e-18 Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 26/198 (13%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + ++FSPDG QVEYA +AV G T+ EK +KL + ++I Sbjct: 137 YDLSNSIFSPDGRNFQVEYAVKAVENGGTSIGIRCKDGVVLAVEKIISSKLLKPGANKRI 196 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D H+ + +GL D R ++RA+ E + ++T + P++ + + G Q YT + Sbjct: 197 ATVDRHIGIVSSGLLPDGRHFVSRARDEADNWRITYKGPISTHVLASRLGGYAQAYTLYS 256 Query: 452 GRRPFGISCLIGGFDYD--------------------------GSPHLFQTEPSGIYYEW 553 RPFG++ +IGG+D + G P L+ EPSG+Y+ + Sbjct: 257 SVRPFGVTSIIGGWDSELELPVDGEVGAGPKSGAGGKVASAKAGGPGLYMIEPSGLYWGY 316 Query: 554 KANATGRSAKTVREFLEK 607 ATG+ + + LEK Sbjct: 317 YGAATGKGRQAAKAELEK 334 >UniRef50_Q7QUL1 Cluster: GLP_436_20835_20083; n=2; Giardia intestinalis|Rep: GLP_436_20835_20083 - Giardia lamblia ATCC 50803 Length = 250 Score = 91.5 bits (217), Expect = 2e-17 Identities = 58/186 (31%), Positives = 90/186 (48%), Gaps = 12/186 (6%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 Y ++T FSP GHL Q+ YA AV G + K + L + T+ + Sbjct: 6 YSFSLTTFSPSGHLRQITYALAAVDGGRLSIGIKCANGVVLMCHKAAENPLVDYPTISLV 65 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + + + ++G +AD R L+N + + + ++ + + + R IA Q+YTQ Sbjct: 66 DNVSPSLGITYSGFSADFRNLLNLGRKSYEQYWNEFQESMPVNMLARDIASTMQEYTQRG 125 Query: 452 GRRPFGISCLIGG--------FDYDGS---PH-LFQTEPSGIYYEWKANATGRSAKTVRE 595 G RPFG S L+ G + +GS P+ L+Q + SG YY WKA A G + R+ Sbjct: 126 GVRPFGCSVLLAGKSMATEHETEANGSRINPYILYQVDSSGSYYTWKACANGNQSSQARD 185 Query: 596 FLEKNY 613 FLEK Y Sbjct: 186 FLEKRY 191 >UniRef50_A4RHU7 Cluster: Proteasome subunit alpha type; n=16; Fungi/Metazoa group|Rep: Proteasome subunit alpha type - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 283 Score = 91.5 bits (217), Expect = 2e-17 Identities = 50/145 (34%), Positives = 82/145 (56%), Gaps = 1/145 (0%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERT 259 M+ RY ++T FSP G L+Q+EYA AV +G TA EKKS + L + + Sbjct: 1 MADRYSFSLTTFSPSGKLVQIEYALNAVNQGVTALGIKATNGIVLATEKKSSSPLTDPSS 60 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRA-QIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 + KI L+ ++ M +AG+ D R+L+++A ++ +K + + + +A + Q+ Sbjct: 61 LSKISLVTPNIGMVYAGMGPDYRVLVDKARKVSHSGYKRIYNEYPPTRILVQDVARVVQE 120 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSP 511 TQS G RP+G+S LI G+D +G P Sbjct: 121 ATQSGGVRPYGVSLLIAGWD-EGIP 144 Score = 53.2 bits (122), Expect = 5e-06 Identities = 25/49 (51%), Positives = 31/49 (63%) Frame = +2 Query: 470 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 IS GG G P L+Q +PSG Y+ WKA A G+SA + + FLEK YT Sbjct: 166 ISGKTGGI-LKGGPMLYQVDPSGSYFPWKATAIGKSAASAKTFLEKRYT 213 >UniRef50_A0CF33 Cluster: Chromosome undetermined scaffold_174, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_174, whole genome shotgun sequence - Paramecium tetraurelia Length = 249 Score = 88.2 bits (209), Expect = 1e-16 Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 1/175 (0%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD ++ +S +G + QVEYA +AV T EK+ ++L E+ T ++I Sbjct: 6 YDLSVATYSQEGRIYQVEYATKAVENSETVIGVKCKDGVILAGEKQKFSRLLEDNTNKRI 65 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D MA G D R ++ RA+ E ++ PV+ ++ +A YT + Sbjct: 66 YNIDTQTGMAICGKLPDGRNILQRAKAESSQYQDMYAIPVSANVLSDRVAQYVHAYTMYS 125 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVR-EFLEKNY 613 G RPFG + I ++ LF EPSG Y + A G+ + EF +N+ Sbjct: 126 GARPFGSATFIASYNTFDGYELFMIEPSGNKYAYHACTHGKGRAVCKSEFERRNF 180 >UniRef50_Q0CFX9 Cluster: Proteasome subunit alpha type; n=12; Pezizomycotina|Rep: Proteasome subunit alpha type - Aspergillus terreus (strain NIH 2624) Length = 311 Score = 87.8 bits (208), Expect = 2e-16 Identities = 47/135 (34%), Positives = 71/135 (52%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + +VFSPDG QVEYA +AV G TA EK +KL + ++I Sbjct: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGGTAIGIRCKDGVVLAVEKIITSKLLKPGANKRI 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D HV + +GL D R ++RA+ E S + + P+ + ++ + Q YT + Sbjct: 68 ATVDRHVGIVSSGLVPDGRHFVSRARDEASSWRGVYKSPIPVSALSNRLGSYVQAYTLYS 127 Query: 452 GRRPFGISCLIGGFD 496 RPFGI+ +IGG+D Sbjct: 128 SVRPFGITAIIGGWD 142 >UniRef50_UPI0000499E10 Cluster: proteasome alpha subunit; n=1; Entamoeba histolytica HM-1:IMSS|Rep: proteasome alpha subunit - Entamoeba histolytica HM-1:IMSS Length = 242 Score = 87.0 bits (206), Expect = 3e-16 Identities = 51/183 (27%), Positives = 85/183 (46%), Gaps = 1/183 (0%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 YDR +T+FSP+G L QVEYA +A + S T +KK +L + TV Sbjct: 6 YDRQLTIFSPEGRLYQVEYALKATKCESLTTVGVCSDEAACIITQKKLPDRLVDPSTVTH 65 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 + + HV +G+ AD +++ R+Q +L + + + + A Q TQ Sbjct: 66 LHRISKHVGCCMSGIYADGKVIAQRSQYYASKFQLDYGYEMPVSLVAKKTADFAQMLTQH 125 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 628 RPFG+S + G+D P L++++P+G ++ A G + LEK E+ Sbjct: 126 AYMRPFGVSSMFIGWDEVSGPQLWRSDPAGSVAAFRGCAAGEKEQEAFNNLEKKKITKEL 185 Query: 629 ATE 637 + Sbjct: 186 TVD 188 >UniRef50_A5K7Q6 Cluster: 20S proteasome alpha subunit G, putative; n=6; Plasmodium|Rep: 20S proteasome alpha subunit G, putative - Plasmodium vivax Length = 253 Score = 86.2 bits (204), Expect = 6e-16 Identities = 49/181 (27%), Positives = 90/181 (49%), Gaps = 3/181 (1%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAK--LQEE 253 +SA YD +++ FSPDG L QVEY +A+ +TA ++ K + + Sbjct: 4 LSAGYDLSVSTFSPDGRLYQVEYIYKAINSNNTALSLECKDGLLTCCVNSNLLKNKMIKH 63 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 + +I ++++V++ +AGL DAR +I+RA+ E S+ L + L + ++ Sbjct: 64 SSYSRIHHINNNVIVTYAGLDGDARNIIDRAKYEANSYYLNFHTNIPLHILANRVSLYLH 123 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK-N 610 +T RPF S ++ FD ++ EP+G Y++ G++ + + +EK N Sbjct: 124 SFTLYWHLRPFASSIILASFDEKEKGEIYCVEPNGACYKYSGVVIGKNKEMFKTEIEKRN 183 Query: 611 Y 613 Y Sbjct: 184 Y 184 >UniRef50_A0NHA5 Cluster: Proteasome subunit alpha type; n=1; Anopheles gambiae str. PEST|Rep: Proteasome subunit alpha type - Anopheles gambiae str. PEST Length = 278 Score = 86.2 bits (204), Expect = 6e-16 Identities = 46/167 (27%), Positives = 80/167 (47%), Gaps = 1/167 (0%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + + FSPDG + Q+EYA +AV T EK +KL E +I Sbjct: 8 YDLSASQFSPDGRVFQIEYAAKAVENSGTVIGLRGKDGVVLAVEKLITSKLYEPDCGTRI 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D + MA +G+ D R +++ A+ E S++ P+ L+ + ++ YT + Sbjct: 68 FTIDTSIGMAISGMITDGRAVVDIARQEAASYRQQNNRPIPLKQLNDRLSSYFHAYTLYS 127 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGI-YYEWKANATGRSAKTV 589 RPFG+S ++ + + P ++ +PSG+ TG S+ T+ Sbjct: 128 AVRPFGVSVILASWSEEKGPEMYMIDPSGVSCVSLSQKQTGESSTTL 174 >UniRef50_A5E6Y2 Cluster: Proteasome component Y7; n=4; Saccharomycetales|Rep: Proteasome component Y7 - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 178 Score = 85.4 bits (202), Expect = 1e-15 Identities = 41/108 (37%), Positives = 69/108 (63%), Gaps = 2/108 (1%) Frame = +2 Query: 296 MAFAGLTADARILINRAQIECQS-HKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 472 M ++G+ D R+L+++A+ Q+ +KL + + + + IA + Q+ TQS G RPFG+ Sbjct: 1 MTYSGMGPDFRVLVDKARKLAQTNYKLIYNEYPPVRIMVQEIAKVMQESTQSGGIRPFGV 60 Query: 473 SCLIGGFD-YDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 S L+GG+D Y L+Q +PSG Y+ WKA A G+++ + + FLEK + Sbjct: 61 SLLVGGYDEYLDKFQLYQVDPSGSYFPWKATAIGKTSNSAKTFLEKRW 108 >UniRef50_A0CDQ2 Cluster: Chromosome undetermined scaffold_17, whole genome shotgun sequence; n=3; Eukaryota|Rep: Chromosome undetermined scaffold_17, whole genome shotgun sequence - Paramecium tetraurelia Length = 245 Score = 85.0 bits (201), Expect = 1e-15 Identities = 51/169 (30%), Positives = 88/169 (52%), Gaps = 1/169 (0%) Frame = +2 Query: 104 ITVFSPDGHLLQVEYAQEAVR-KGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLL 280 IT+FSP+G L QVEYA +AV+ G T+ EK+ KL +E++V + + Sbjct: 12 ITLFSPEGRLYQVEYAFKAVKTSGLTSIGVKGTDTVCLITEKRVPDKLIDEKSVTNLFNV 71 Query: 281 DDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRR 460 + + G+ +DAR L+ R + E +L ++ +++ +A L Q TQ R Sbjct: 72 SEKIGALTTGIPSDARALVTRMRYEAGEFRLKNGYYCPVDVLSKRMADLAQTNTQYYQMR 131 Query: 461 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 +G+ ++ +D + P L++ +PSG Y +KA A+G + +LEK Sbjct: 132 SYGVETILCQYDDELGPLLYKLDPSGHYSGYKATASGVKEQEAINYLEK 180 >UniRef50_O17586 Cluster: Proteasome subunit alpha type-6; n=9; Bilateria|Rep: Proteasome subunit alpha type-6 - Caenorhabditis elegans Length = 246 Score = 83.4 bits (197), Expect = 4e-15 Identities = 54/176 (30%), Positives = 81/176 (46%), Gaps = 1/176 (0%) Frame = +2 Query: 83 SARYDRAITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEERT 259 SA +DR IT+FSP+G + QVEYA +A+ + TA +K+ L T Sbjct: 6 SAGFDRHITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSLIVADT 65 Query: 260 VRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKY 439 V + + V G+ DA+ I RAQ E S K + E + + +A L Q Y Sbjct: 66 VTSVYQISQSVGCCAIGMIPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMADLNQYY 125 Query: 440 TQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 TQ+ R G + L +D + P +++ +P+G Y K + G FLEK Sbjct: 126 TQNAEMRSLGCALLFISYDDEKGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFLEK 181 >UniRef50_Q94II8 Cluster: Proteasome subunit alpha type; n=3; Oryza sativa|Rep: Proteasome subunit alpha type - Oryza sativa subsp. japonica (Rice) Length = 253 Score = 81.4 bits (192), Expect = 2e-14 Identities = 48/175 (27%), Positives = 81/175 (46%), Gaps = 1/175 (0%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVR 265 A Y+R IT+FSP+G L Q++YA AV+ + KL + T+ Sbjct: 21 ADYERFITLFSPEGRLCQLDYAFNAVKLAGITSVGVRGDDSVYVLTHRKEDKLHDPTTIT 80 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 + + D + + G+ D R + A+ + ++ + ++IA Q TQ Sbjct: 81 NLFAITDRIGLLATGMPGDGRAIAQEARNAAAEFRFKWGYKMSPCMLAQWIADRAQIRTQ 140 Query: 446 SNGRRPFGISCLIGGFDYD-GSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RP+G+ +I G D + G+P LF +P+G ++ KA + G K V FLE+ Sbjct: 141 HAQIRPYGVVSMIFGIDEEKGTPELFTCDPAGQFFAHKATSAGPKEKEVMNFLEE 195 >UniRef50_Q9NDA3 Cluster: 20S proteasome alpha 7 subunit; n=1; Trypanosoma brucei|Rep: 20S proteasome alpha 7 subunit - Trypanosoma brucei Length = 237 Score = 80.2 bits (189), Expect = 4e-14 Identities = 49/172 (28%), Positives = 79/172 (45%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 +D++ +FS DG + QVEYA +AV GSTA EK +++ EE + +I Sbjct: 6 HDQSTDIFSADGRVFQVEYACKAVDNGSTAVAACCKDGVVVAVEKILTSRMLEEGSNNRI 65 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D + G+ D +++RA+ E ++ + P+ + I YT Sbjct: 66 HAVDRQAGICVCGVLPDGLAVVSRARGEAENSRDIFSTPILGSLLASRIGEFMHVYTTHY 125 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG S +I + DG P L+ +PSG + A G+ + LEK Sbjct: 126 AYRPFGCSVIIASYADDG-PQLYVADPSGAVAGYYGIALGKGKTVAKTELEK 176 >UniRef50_Q00ZK2 Cluster: Proteasome subunit alpha type; n=2; Ostreococcus|Rep: Proteasome subunit alpha type - Ostreococcus tauri Length = 262 Score = 79.4 bits (187), Expect = 7e-14 Identities = 50/172 (29%), Positives = 79/172 (45%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + T +SPDG + QVEYA +AV G EK +KL + T R+ Sbjct: 68 YDLSTTTYSPDGRVFQVEYAGKAVDAGGLTVGVKCVDGVVIACEKLVPSKLHKPGTNRRT 127 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + H + +G T D + +RA+ EC ++K D + + + +A +T Sbjct: 128 RAVARHAGVGGSGYTPDLAAVADRARAECANYKSFYGDAIPGKVLAERMAHYYHLFTLYW 187 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG S L+G D+DG HL+ E +G + + G+ + +EK Sbjct: 188 SVRPFGCSTLLGCKDFDGY-HLYLVEQNGECAKMRGACIGKGKNAAKTEVEK 238 >UniRef50_Q09583 Cluster: Proteasome subunit alpha type-3; n=2; Caenorhabditis|Rep: Proteasome subunit alpha type-3 - Caenorhabditis elegans Length = 250 Score = 79.4 bits (187), Expect = 7e-14 Identities = 52/172 (30%), Positives = 78/172 (45%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD A + FSPDG + QVEYAQ+AV T +K +KL + ++ Sbjct: 8 YDLAASTFSPDGRIFQVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYTDNANPRM 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 ++D+V +A AG D L N A E +P+ ++ I +A +T Sbjct: 68 FNVNDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYIHIHTLGI 127 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG ++ LF EPSG+ YE+KA A G+ + + +EK Sbjct: 128 S-RPFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEK 178 >UniRef50_Q7QUP6 Cluster: GLP_47_22543_21776; n=2; Giardia intestinalis|Rep: GLP_47_22543_21776 - Giardia lamblia ATCC 50803 Length = 255 Score = 75.8 bits (178), Expect = 8e-13 Identities = 49/184 (26%), Positives = 84/184 (45%), Gaps = 3/184 (1%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD + FSP G L Q+ YA EA GS + ++ L + K+ Sbjct: 3 YDSDVATFSPTGKLNQITYAMEAPSFGSPSVGLASKDAVVLVAVRRQTTPLSSFQD--KL 60 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 +D H+ + +G+ ADA ++ + EC + + P + + +A Q TQ Sbjct: 61 FEVDKHIGICISGIYADAYKMLRLLRDECTEYTYVYDTPHPVGPLVAKLAEDAQARTQFW 120 Query: 452 GRRPFGISCLIGGFDYDG---SPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G RP+G S LIGG D +P L+ P+ ++ E++A + G ++T+ L+ + Sbjct: 121 GYRPYGASLLIGGIDTRNNKQTPRLYVLSPNAVFKEYRAVSLGMGSQTINTHLKSHVDEY 180 Query: 623 EVAT 634 E A+ Sbjct: 181 ENAS 184 >UniRef50_Q8SR59 Cluster: PROTEASOME ALPHA SUBUNIT C6; n=1; Encephalitozoon cuniculi|Rep: PROTEASOME ALPHA SUBUNIT C6 - Encephalitozoon cuniculi Length = 234 Score = 74.9 bits (176), Expect = 1e-12 Identities = 49/171 (28%), Positives = 75/171 (43%) Frame = +2 Query: 110 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDH 289 +F+ DG LLQ+EY EAV G +K KL+E + + Sbjct: 10 IFNSDGKLLQIEYGLEAVNNGLPVVTAKSKDMIVCVSKKIPQDKLEESEAT-SFHRVSEK 68 Query: 290 VVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFG 469 +A GL D ++ R ++ + VT + + R A Q+ QS+ R Sbjct: 69 CYVAITGLPGDTDYVVKRIKMVANRKAFSFGFEVTPDILCRSFADKVQQLIQSSAERSAA 128 Query: 470 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 + I GFD + P ++QT+ SGI Y A A G + +F+EKNY +D Sbjct: 129 FNASIFGFDKE-RPMIYQTDMSGISYPCYATAAGEKHGKMTKFIEKNYRSD 178 >UniRef50_UPI000150A654 Cluster: Proteasome A-type and B-type family protein; n=1; Tetrahymena thermophila SB210|Rep: Proteasome A-type and B-type family protein - Tetrahymena thermophila SB210 Length = 244 Score = 74.5 bits (175), Expect = 2e-12 Identities = 48/174 (27%), Positives = 80/174 (45%), Gaps = 1/174 (0%) Frame = +2 Query: 95 DRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKIC 274 D ++T F+ DG++ QVEYAQ+AV T EKK KL E + R+I Sbjct: 3 DLSVTTFTQDGYIKQVEYAQKAVSDSETILGVRCKDGVILGAEKKLQTKLMVEDSDRRIY 62 Query: 275 LLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNG 454 + ++ M G D R +++RA+ E Q ++ P++ ++ +T Sbjct: 63 NIQKNIGMIVGGRIPDGRNVVHRARKEAQEYEKYFSMPISGRILSERTGQYLHAHTLYGA 122 Query: 455 RRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTV-REFLEKNY 613 RPFG S +I +D L Q++ +G + A A G+ + V F +N+ Sbjct: 123 YRPFGCSVIISSYDPIDGLQLHQSDNAGYCLGYYACAQGQGKQEVMAHFGRRNF 176 >UniRef50_Q98RW3 Cluster: Similar to proteasome A-type submit; n=1; Guillardia theta|Rep: Similar to proteasome A-type submit - Guillardia theta (Cryptomonas phi) Length = 233 Score = 74.1 bits (174), Expect = 3e-12 Identities = 41/173 (23%), Positives = 90/173 (52%) Frame = +2 Query: 104 ITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLD 283 ++ F+ G + Q+EYA +AV + +T S K + K+ +++ Sbjct: 6 LSSFNSKGKISQIEYASKAVLQSNTVISVKGNNLLLTLTLDISNKKNIFTQIEPKVFIIN 65 Query: 284 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRP 463 +++++ +GL +D I+I++A+ C+ + ++ +++ ++ Q +T S+G RP Sbjct: 66 KYIILSASGLKSDIIIVISKARSICRDFQHKYGHQISTASLSKDLSSFLQNFTSSSGFRP 125 Query: 464 FGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 G+S I G D DG P LF+ SG + ++ G+S+K ++E++ + ++ Sbjct: 126 LGVSLNILGIDKDG-PELFEINTSGEINDVNFSSIGKSSKDIKEYIRARWCSN 177 >UniRef50_A4RSN5 Cluster: Proteasome subunit alpha type; n=2; Ostreococcus|Rep: Proteasome subunit alpha type - Ostreococcus lucimarinus CCE9901 Length = 236 Score = 72.5 bits (170), Expect = 8e-12 Identities = 50/182 (27%), Positives = 82/182 (45%) Frame = +2 Query: 89 RYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +YD+ + +SP G L QVEYA EAV++GST K+ +KL + K Sbjct: 5 QYDQDMLTWSPQGRLHQVEYAMEAVKQGSTVVACGNKKCAVLAALKRKQSKLSSMQ--EK 62 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I ++ V +A +GL+ D L+ + E + + + Q + Sbjct: 63 IFAINTRVGVAVSGLSTDGAKLVKLLREESTREEFVYGRSACPGRLAAAASKSLQISMRK 122 Query: 449 NGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 628 + RP G+ ++ G +FQT PSG ++ A G +++ R +LEKN A E Sbjct: 123 SSGRPCGVGLVLVGSSEQLGCQIFQTCPSGEVHQMSCTAIGGRSQSARTYLEKNMEALET 182 Query: 629 AT 634 A+ Sbjct: 183 AS 184 >UniRef50_Q98S57 Cluster: 26S proteasome SU; n=1; Guillardia theta|Rep: 26S proteasome SU - Guillardia theta (Cryptomonas phi) Length = 232 Score = 72.1 bits (169), Expect = 1e-11 Identities = 44/169 (26%), Positives = 84/169 (49%), Gaps = 1/169 (0%) Frame = +2 Query: 110 VFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICL-LDD 286 ++S DG + Q+E+A E + K ++A +K+ K E+ + L+ Sbjct: 5 LYSHDGRVEQLEFALELIDKSNSAIGIIYEKGILFATMEKN--KHNSEKEYQNFTFALEK 62 Query: 287 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 466 +++ +G DA ++ + +KL ++ V +E I Y++ + K TQ +RP Sbjct: 63 NIICIASGNIPDANTILFYLKSFADEYKLMFQETVPIEKIVGYLSDIMHKPTQMIYQRPL 122 Query: 467 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 G+S +IGG+D LF+ +PSG + W+A + G + + +E+NY Sbjct: 123 GVSFIIGGWDEFRGFQLFKIDPSGNFSGWRATSIGFNNILNQTLIEENY 171 >UniRef50_Q5CUM9 Cluster: Proteasome subunit alpha1; n=3; Cryptosporidium|Rep: Proteasome subunit alpha1 - Cryptosporidium parvum Iowa II Length = 252 Score = 72.1 bits (169), Expect = 1e-11 Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 7/179 (3%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKK------SVAKLQE 250 +DR IT+FSP+G L Q+EY AV+ + TA EKK KL + Sbjct: 9 HDRHITIFSPEGKLYQIEYTFRAVKNSNITAIAIKGKDTVCIVCEKKVPNQQGQQDKLLD 68 Query: 251 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 430 V + + H+ GL D R +I++ + + + Y++ IA + Sbjct: 69 PAYVTSLYKVRKHIGAVMLGLAPDCRSIISKCREIAGKFAFEKGVEIPVSYLSHKIADVN 128 Query: 431 QKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 Q YTQ R G S + D + P L++ +P+G + ++A A G + LEK Sbjct: 129 QLYTQHASMRLLGASGMFISIDDEDGPSLYKIDPAGYFASYRACAVGTKEREGNNALEK 187 >UniRef50_Q8SRU7 Cluster: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9; n=1; Encephalitozoon cuniculi|Rep: 26S PROTEASOME ALPHA-TYPE SUBUNIT C9 - Encephalitozoon cuniculi Length = 232 Score = 71.7 bits (168), Expect = 1e-11 Identities = 52/174 (29%), Positives = 77/174 (44%), Gaps = 2/174 (1%) Frame = +2 Query: 113 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 292 F+ +G L QVE+A + V + T V K + KI L D + Sbjct: 11 FTDEGRLPQVEFAIKNVSRAGTIIGYVCSDGVVLM----GVNKEPTNGPMEKIYQLSDSI 66 Query: 293 VMAFAGLTADARILINRAQIECQS--HKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 466 GL DA L A+I+ Q + VE P+T + +++ KQ +TQ G RPF Sbjct: 67 YCVLCGLFGDAMELKRYARIKAQEVLERFGVECPLTT--LCKFVGQRKQAFTQYAGTRPF 124 Query: 467 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEV 628 G+S L G DG L T+PSG WK G + + + L+ ++ DE+ Sbjct: 125 GVSFLYAGV-IDGKYALMSTDPSGTSNRWKGMCYGENEEAINRGLKNDFPEDEM 177 >UniRef50_Q8SR95 Cluster: 20S PROTEASOME COMPONENT C3; n=1; Encephalitozoon cuniculi|Rep: 20S PROTEASOME COMPONENT C3 - Encephalitozoon cuniculi Length = 233 Score = 70.5 bits (165), Expect = 3e-11 Identities = 50/172 (29%), Positives = 80/172 (46%), Gaps = 1/172 (0%) Frame = +2 Query: 95 DRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKIC 274 ++ +T+FS +G L Q + A A GS + K V L VRK+ Sbjct: 6 EKPVTLFSSEGKLGQCDNALRAAVNGSLSIGASAADGAVLM-SFKDVPPLVIREEVRKVF 64 Query: 275 LLDDHVVMAFAGLTADARILIN-RAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 + D + ++GL D RI +N QI + + + P ++ T + + + Q+YTQ + Sbjct: 65 KICDTIGCTYSGLQPDCRIQVNIGCQIAEEYYDVYGRYP-DVDVFTAHFSSVVQEYTQKS 123 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 G RPFG + G G P L+Q +PSG Y A+G R+F+E+ Sbjct: 124 GYRPFGTLMIFAG-PVRGVPRLYQVDPSGSYQTADVCASGVGYSDARKFVER 174 >UniRef50_Q98RV9 Cluster: 26S proteasome SU A5; n=1; Guillardia theta|Rep: 26S proteasome SU A5 - Guillardia theta (Cryptomonas phi) Length = 232 Score = 68.5 bits (160), Expect = 1e-10 Identities = 50/174 (28%), Positives = 81/174 (46%), Gaps = 5/174 (2%) Frame = +2 Query: 116 SPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHVV 295 SP+G L +EYAQEA GST+ E+K L + +KI +LD + Sbjct: 8 SPEGRLKDLEYAQEAANLGSTSCGIKTKDFIFILSERKKKKSL-DYLNDQKIYVLDKNKG 66 Query: 296 MAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN-----GRR 460 +GL +D+R +I+ +I C++ + ++E + I L Y +N R Sbjct: 67 CCVSGLISDSRKIIDNVRIYCENKYFLINSYPSIEECSNLINNLITSYNTNNDVNKISPR 126 Query: 461 PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 P G S L+ G + L + +PSG Y + K A G +K V L++ Y ++ Sbjct: 127 PLGTSFLLFG-KSNKKLELIKVDPSGRYIKDKILAIGEGSKDVLIILQEGYRSN 179 >UniRef50_Q7QSC8 Cluster: GLP_105_6759_5881; n=2; Giardia intestinalis|Rep: GLP_105_6759_5881 - Giardia lamblia ATCC 50803 Length = 292 Score = 67.7 bits (158), Expect = 2e-10 Identities = 52/191 (27%), Positives = 85/191 (44%), Gaps = 11/191 (5%) Frame = +2 Query: 71 FLT-MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQ 247 F+T + + YD + +SPDG + QV+YA +AV + +K ++ + Sbjct: 20 FMTAVGSGYDVSCGSYSPDGKIFQVDYALKAVEQHGLCVGIRTSGGVALAVQK-NIHDIL 78 Query: 248 EERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGL 427 E + ++D +V+A AGL D +L+++A+ +S++ V + I+G Sbjct: 79 EIDSAPCFYQIEDSIVIAVAGLQPDGMVLVSKAREVAESYRENYSRIVPTGVLANSISGY 138 Query: 428 KQKYTQSNGRRPFGISCLIGGFDYDGSP----------HLFQTEPSGIYYEWKANATGRS 577 Q YT RPFG S LI G+D S L+ +PSG A A GR Sbjct: 139 MQLYTHYGEVRPFGCSLLIAGYDSIASADEPTTLKTKYSLYLLQPSGDITNCFATAAGRH 198 Query: 578 AKTVREFLEKN 610 + LE + Sbjct: 199 TSQAKVELENH 209 >UniRef50_Q4N061 Cluster: Proteasome subunit alpha type 3, putative; n=3; Piroplasmida|Rep: Proteasome subunit alpha type 3, putative - Theileria parva Length = 267 Score = 67.3 bits (157), Expect = 3e-10 Identities = 53/196 (27%), Positives = 84/196 (42%), Gaps = 20/196 (10%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSV-------- 235 + A YD +++ FSPDG + QVEYA +AV TA + + Sbjct: 4 IGAGYDLSVSTFSPDGRVFQVEYATKAVDSAPTAVAAVFSDGIVFAADSLACGAQDDSPY 63 Query: 236 AKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRY 415 A + + + ++ +D+ + A AGL DA+ ++ RAQ EC+S + I Sbjct: 64 ANVLQAKPAWRVFAVDERMGAAVAGLLPDAKCVVRRAQEECKSFLKEYGTKAPVRVIAER 123 Query: 416 IAGLKQKYTQSNGRRPFGISCLIGGFDYDGSP------------HLFQTEPSGIYYEWKA 559 +A YT RPFG+S L+ G + + S L+ E SG Y++ Sbjct: 124 VALFVHAYTLYWHVRPFGVSILLAGTNENNSRTTYSVLQLFTSYELYCIEGSGACYKYGG 183 Query: 560 NATGRSAKTVREFLEK 607 A G+ + LEK Sbjct: 184 MAIGKGKHIAKTELEK 199 >UniRef50_Q7QW44 Cluster: GLP_457_25625_26368; n=2; Giardia intestinalis|Rep: GLP_457_25625_26368 - Giardia lamblia ATCC 50803 Length = 247 Score = 63.3 bits (147), Expect = 5e-09 Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 2/162 (1%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVR-KGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRK 268 +D+A+TVF+P+G L QVEYA AV+ G + + +S +L + Sbjct: 7 FDQALTVFNPEGKLFQVEYAFRAVKTSGLSHVAIRCLDGVVLVSQLQSADRLVDTANNTF 66 Query: 269 ICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS 448 I +++ G AD R +I+R + E T + + +A + Q YTQ Sbjct: 67 IHEINETSACMICGRIADGRRVIDRVRSEAVDFFRKWNYQPTADILCTRLADINQIYTQE 126 Query: 449 NGRRPFGISCLIGGFDYDGSPH-LFQTEPSGIYYEWKANATG 571 +RPFG + G+D + LF+T+P+G + A A G Sbjct: 127 AWQRPFGNIAVFAGWDPEQDRSLLFKTDPAGTNTGYFAIAVG 168 >UniRef50_Q9GU37 Cluster: Proteasome subunit alpha type-1; n=8; Trypanosomatidae|Rep: Proteasome subunit alpha type-1 - Trypanosoma brucei brucei Length = 266 Score = 62.1 bits (144), Expect = 1e-08 Identities = 50/180 (27%), Positives = 77/180 (42%), Gaps = 6/180 (3%) Frame = +2 Query: 86 ARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVA-KLQEERTV 262 A +D+ ITVFSP+G L QVEYA +AV + SV KL T+ Sbjct: 4 AGFDKYITVFSPEGSLYQVEYAFKAVTYAGLLTVAIRCKDAVLVFTQHSVPDKLMRPETI 63 Query: 263 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 442 + ++D+ + G D + L+ +A+ E +K P+ + + + + Q T Sbjct: 64 TSLYNVNDNTGVCITGRAPDGKALVQKARNEASEYKYRYGMPMLVSVLAKPWQDMAQVRT 123 Query: 443 QSNGRRPFGISCLIGGF---DYDGS--PHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 Q G R G G D DG+ P ++ +P+G A A G+ FLEK Sbjct: 124 QQAGMRLMGTIMTFVGMEQNDEDGAWIPQIYCVDPAG-GAAVHACAVGKKQIEACAFLEK 182 >UniRef50_Q9YER0 Cluster: Proteasome beta subunit; n=1; Aeropyrum pernix|Rep: Proteasome beta subunit - Aeropyrum pernix Length = 219 Score = 60.1 bits (139), Expect = 4e-08 Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 1/158 (0%) Frame = +2 Query: 152 QEAVRKGSTAXXXXXXXXXXXXXEKKSVAK-LQEERTVRKICLLDDHVVMAFAGLTADAR 328 + VR G+T +K++ A L R V+KI +L ++V M +GL ADA+ Sbjct: 19 ERVVRSGTTTVGLIASDHVILAADKRATAGFLIASRRVKKIVMLSNYVAMTVSGLVADAQ 78 Query: 329 ILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS 508 IL + + E + +++T + ++ R++A L S+ P+ + ++GG YD Sbjct: 79 ILSDVLREEIRLYEMTNK----VKPSVRFVASLLSNILFSSKFFPYIVQLIVGG--YDTQ 132 Query: 509 PHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 P L+ + G E K ATG + LE+ Y D Sbjct: 133 PRLYTLDLFGSITEDKYTATGSGSPIAYGVLEERYRED 170 >UniRef50_Q4U9U5 Cluster: Proteasome subunit alpha type; n=3; Piroplasmida|Rep: Proteasome subunit alpha type - Theileria annulata Length = 276 Score = 59.7 bits (138), Expect = 6e-08 Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 9/181 (4%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRK-GSTAXXXXXXXXXXXXXEKKSVAK------LQE 250 YDR IT+FSP+G L Q+EYA +AV+ T +KK A+ L + Sbjct: 9 YDRHITIFSPEGKLFQLEYALKAVKNCNLTGLAIKDDSAIAVVAQKKLPAQQGNQDVLLD 68 Query: 251 ERTVRKICLLDDHVVMAFAGLTADA-RILINRAQIECQ-SHKLTVEDPVTLEYITRYIAG 424 +V + + D + GL D IL Q+ S+K + P ++ + + I+ Sbjct: 69 TSSVTSLYHITDEIFALLVGLPGDCLSILYKARQVALDYSYKYGINIPASV--LCQKISD 126 Query: 425 LKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 604 L Q YTQ R + LI + D P +++ + SG + +KA G + LE Sbjct: 127 LNQVYTQHAYMRLHACTGLILSIEPDVGPKIYKFDSSGWFAGYKACGIGAKEQESENALE 186 Query: 605 K 607 K Sbjct: 187 K 187 >UniRef50_A2D8G5 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 240 Score = 59.7 bits (138), Expect = 6e-08 Identities = 42/172 (24%), Positives = 71/172 (41%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKI 271 YD FSPDG QVEYA +AV K S A EK + L +I Sbjct: 8 YDFNPITFSPDGRQFQVEYATKAVEKDSLALGVKCKDGILLAAEKNLTSTLLTPGGNPRI 67 Query: 272 CLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSN 451 ++D + A G D ++ +++ ++ +T+ + ++ Sbjct: 68 FWINDSIACATIGHRPDCYSIVEQSRNRAETFTSNFGIKITVPQLASEVSQQFHLAHYYQ 127 Query: 452 GRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 RPFG + + + D L+ EPSG +Y + A+ G+++ R L+K Sbjct: 128 AYRPFGCTVIFASYKDDA---LYAIEPSGAFYGYFASCFGKNSNLARAELQK 176 >UniRef50_A2F568 Cluster: Family T1, proteasome alpha subunit, threonine peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T1, proteasome alpha subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 241 Score = 59.3 bits (137), Expect = 8e-08 Identities = 48/178 (26%), Positives = 80/178 (44%), Gaps = 2/178 (1%) Frame = +2 Query: 80 MSARYDRAITVFSPDGHLLQVEYAQEAVRKGS-TAXXXXXXXXXXXXXEKKSVAKLQEER 256 MS+ DR +TVFS +G L QVEY+ +AV++ TA +KK KL + Sbjct: 1 MSSGADRYLTVFSAEGRLWQVEYSFKAVKQAEVTAVAVKSKNAVCVAVQKKVSDKLIDPS 60 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 TV + + D+V GL +D ++ + + + + + + + ++ Q Sbjct: 61 TVTHMYRITDNVGACLVGLPSDVNFIVMLLRSFANNFEYKQGFSIPVSILAQMLSERHQL 120 Query: 437 YTQSNGRRPFGISCLIGGFD-YDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 +Q RP +S ++ G D S L++ EPSG ++A A G LEK Sbjct: 121 ESQLVYVRPSAVSAILFGLDGPSDSFALYKIEPSGYSNGFRAVACGVKEIEAMSALEK 178 >UniRef50_Q3TEL1 Cluster: 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920013M15 product:proteasome (prosome, macropain) subunit, alpha type 3, full insert sequence; n=13; Euteleostomi|Rep: 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920013M15 product:proteasome (prosome, macropain) subunit, alpha type 3, full insert sequence - Mus musculus (Mouse) Length = 180 Score = 58.4 bits (135), Expect = 1e-07 Identities = 31/104 (29%), Positives = 54/104 (51%) Frame = +2 Query: 296 MAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGIS 475 MA AGL ADAR L + A+ E + + + L+++ +A YT + RPFG S Sbjct: 1 MAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCS 60 Query: 476 CLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 ++G + + L+ +PSG+ Y + A G++ + + +EK Sbjct: 61 FMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK 104 >UniRef50_Q98S33 Cluster: 26S proteasome SU alpha7; n=1; Guillardia theta|Rep: 26S proteasome SU alpha7 - Guillardia theta (Cryptomonas phi) Length = 241 Score = 57.2 bits (132), Expect = 3e-07 Identities = 43/176 (24%), Positives = 74/176 (42%) Frame = +2 Query: 77 TMSARYDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEER 256 ++ + YD T+F+P+G LLQ+EY+ + + K + A E S + Sbjct: 3 SIKSGYDLLPTIFTPEGKLLQLEYSSKCINKSNIALGIKCNDGLIIFKEIDSNQYNNDII 62 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 I L+ ++ M +G+T D R L NR E K + +Y+T ++ L Sbjct: 63 ECNMIFCLNHYMAMTSSGITGDFRSLCNRLVDENLIEKYRYGLELNSKYLTHLLSRLFHL 122 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 604 + S RP ++G DY S +F G + +TG + + + LE Sbjct: 123 NSNSWSLRPLACDIILGFIDY-SSLEIFFISNQGSIIKTNNISTGSACELINFELE 177 >UniRef50_Q9YES4 Cluster: Proteasome beta subunit; n=1; Aeropyrum pernix|Rep: Proteasome beta subunit - Aeropyrum pernix Length = 203 Score = 57.2 bits (132), Expect = 3e-07 Identities = 34/120 (28%), Positives = 55/120 (45%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 R +KI +++D + +AFAGL D L+ + + + L P T+ + ++++ L Sbjct: 34 RNFKKIFVINDRIGIAFAGLYGDMGGLVRIVEGQMRLASLETGKPATVRNVAKFLSSLLY 93 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 Y PF + ++GG D G P L+ +P G E A G A T LE Y Sbjct: 94 SYKFF----PFNVEAIVGGIDPGGEPKLYVLDPLGSIIEEDYVAAGTGATTAFGLLEHVY 149 >UniRef50_Q8TW10 Cluster: Protease subunit of the proteasome; n=2; Euryarchaeota|Rep: Protease subunit of the proteasome - Methanopyrus kandleri Length = 210 Score = 53.6 bits (123), Expect = 4e-06 Identities = 36/154 (23%), Positives = 72/154 (46%), Gaps = 1/154 (0%) Frame = +2 Query: 155 EAVRKGSTAXXXXXXXXXXXXXEKKSV-AKLQEERTVRKICLLDDHVVMAFAGLTADARI 331 + + KG+T ++++V L + V+KI + D++ + AG ADA+ Sbjct: 5 DQLTKGTTTVGILADKGVVLAADRRAVMGNLIAGKQVKKIFRIHDYIGVTTAGSVADAQK 64 Query: 332 LINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSP 511 +++ + E + ++L ++ + I+ + ++ RP+ + ++GGF+ D P Sbjct: 65 IVDLMRAEARLYELRHNRMISARALANMISHVL--HSSLKAFRPYLVQLIVGGFN-DDDP 121 Query: 512 HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 L+ +PSG E ATG + T LE Y Sbjct: 122 ALYNLDPSGSIIEEDYTATGSGSPTAYGVLEAEY 155 >UniRef50_A3DN21 Cluster: 20S proteasome, A and B subunits; n=1; Staphylothermus marinus F1|Rep: 20S proteasome, A and B subunits - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 213 Score = 52.8 bits (121), Expect = 7e-06 Identities = 31/123 (25%), Positives = 58/123 (47%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 + RK+ + HV + FAGL DA+ +I ++E ++++L + + + + + ++ + Sbjct: 46 KNTRKVHPITKHVGIGFAGLVGDAQFIIRALRMEAENYELQLGREIRVRGLAKILSLILY 105 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 Y + P ++GGFD G P ++ +P G E K A G +EK Y Sbjct: 106 SYKLA----PLMTEVVVGGFDEKG-PQIYVLDPVGSLIEDKYVALGSGGPIALGIIEKEY 160 Query: 614 TAD 622 D Sbjct: 161 RED 163 >UniRef50_A0RXV1 Cluster: 20S proteasome, alpha and beta subunit; n=1; Cenarchaeum symbiosum|Rep: 20S proteasome, alpha and beta subunit - Cenarchaeum symbiosum Length = 195 Score = 52.8 bits (121), Expect = 7e-06 Identities = 36/124 (29%), Positives = 59/124 (47%) Frame = +2 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI +DDH + AG ADA+ +++ + H++ + P+ ++ + R + + + Q Sbjct: 30 KIQRIDDHAGLTLAGGVADAQNIVDVLRYHASLHRIRKQGPIPIKSLARLTSLI---FHQ 86 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 625 + G PF L+GGFD G P L+ + G E TG + LE+ Y AD Sbjct: 87 NRG-YPFMADILMGGFDAVG-PALYNIDMFGSVEEKSYVTTGSGSPVAYGTLEEEYRADL 144 Query: 626 VATE 637 A E Sbjct: 145 TADE 148 >UniRef50_A2BN24 Cluster: Proteasome beta subunit; n=2; Desulfurococcales|Rep: Proteasome beta subunit - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 204 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/123 (26%), Positives = 56/123 (45%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 +T RK+ + D++ +A AGL AD + + + E + + + +++ + R +A + Sbjct: 37 KTARKVYKITDYLGLALAGLFADLQAISKILRAEIEYYNIVTGRRISVRAVARLLATILY 96 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 Y PF L+GG + DG+ L+ +P G E A G A LE Y Sbjct: 97 SYKYY----PFLSETLVGGLEADGTAKLYVMDPLGSLIEDDYAAIGSGAPIAIGILENGY 152 Query: 614 TAD 622 + D Sbjct: 153 SKD 155 >UniRef50_Q8IAR3 Cluster: Proteasome subunit alpha, putative; n=5; Plasmodium|Rep: Proteasome subunit alpha, putative - Plasmodium falciparum (isolate 3D7) Length = 284 Score = 50.8 bits (116), Expect = 3e-05 Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 7/125 (5%) Frame = +2 Query: 92 YDRAITVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVA-------KLQE 250 YDR +T+FSPDG+L Q+EYA +AV+ + +K +A KL + Sbjct: 9 YDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLD 68 Query: 251 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 430 + I + D + + G+ D ++ +A+ E + V E + R I Sbjct: 69 YNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKI 128 Query: 431 QKYTQ 445 Q YTQ Sbjct: 129 QVYTQ 133 >UniRef50_Q8ZST5 Cluster: Proteasome, beta subunit; n=5; Thermoproteaceae|Rep: Proteasome, beta subunit - Pyrobaculum aerophilum Length = 203 Score = 50.4 bits (115), Expect = 4e-05 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 1/162 (0%) Frame = +2 Query: 155 EAVRKGSTAXXXXXXXXXXXXXEKK-SVAKLQEERTVRKICLLDDHVVMAFAGLTADARI 331 E V+ G+TA EK+ S +K+ ++DD + +A AG+ AD + Sbjct: 3 EEVQIGATAVGIKAKDGVVLAAEKRVSYGFYTLSSAGKKVFVIDDKLAIASAGIIADMQT 62 Query: 332 LINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSP 511 L ++ ++++L ++ + T +A L S PF L+GG D +G P Sbjct: 63 LAKILKLNAKAYELEMKRKPS----THSMARLLSVIMFSRRFMPFFAEVLVGGIDEEG-P 117 Query: 512 HLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATE 637 HL +P G E A G AK L+ Y D E Sbjct: 118 HLIVMDPLGSLIEDNYAALGTGAKLAVAVLDTGYRPDITVEE 159 >UniRef50_A7DQ84 Cluster: Proteasome endopeptidase complex; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Proteasome endopeptidase complex - Candidatus Nitrosopumilus maritimus SCM1 Length = 210 Score = 49.6 bits (113), Expect = 6e-05 Identities = 33/124 (26%), Positives = 57/124 (45%) Frame = +2 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI +DDH + AG ADA+ +++ + H++ P+++ + R + + + Q Sbjct: 45 KIQKIDDHAGLTLAGGVADAQNIVDILRYHSNLHRVEKHGPISIHSLARLCSLI---FHQ 101 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADE 625 + G PF L+GG+D +G P LF + G + TG + LE+ Y D Sbjct: 102 NRG-YPFMADILVGGYDAEG-PALFNIDMFGSVEKKAYVTTGSGSPVAYGLLEEEYREDL 159 Query: 626 VATE 637 E Sbjct: 160 TVEE 163 >UniRef50_Q9P996 Cluster: Proteasome subunit beta precursor; n=10; Euryarchaeota|Rep: Proteasome subunit beta precursor - Archaeoglobus fulgidus Length = 213 Score = 48.4 bits (110), Expect = 1e-04 Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 2/159 (1%) Frame = +2 Query: 152 QEAVRKGSTAXXXXXXXXXXXXXEKKS-VAKLQEERTVRKICLLDDHVVMAFAGLTADAR 328 +E + KG+T EK++ + + +KI + D + M AG DA+ Sbjct: 5 EEKIYKGTTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQ 64 Query: 329 ILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS 508 L +IE +++ E T+ I + L Y P+ + LIGG D +G Sbjct: 65 FLARIIKIEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGK 120 Query: 509 PHLFQTEPSGIYYEWK-ANATGRSAKTVREFLEKNYTAD 622 ++ +P G E K ATG + T LE +T + Sbjct: 121 -SIYSIDPIGGAIEEKDIVATGSGSLTAYGVLEDRFTPE 158 >UniRef50_Q58634 Cluster: Proteasome subunit beta precursor; n=9; Euryarchaeota|Rep: Proteasome subunit beta precursor - Methanococcus jannaschii Length = 224 Score = 47.6 bits (108), Expect = 3e-04 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 2/156 (1%) Frame = +2 Query: 161 VRKGSTAXXXXXXXXXXXXXEKK-SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILI 337 V KG+T +K+ S+ L ++ +K+ +DD++ M AG DA+ ++ Sbjct: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 Query: 338 NRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHL 517 E + +K+ + A L S+ PF +IGG+D L Sbjct: 63 RLLIAEAKLYKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 Query: 518 FQTEPSGIYYEWKA-NATGRSAKTVREFLEKNYTAD 622 F +P G E K ATG + LE Y D Sbjct: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD 154 >UniRef50_A7SI53 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1628 Score = 47.2 bits (107), Expect = 3e-04 Identities = 26/70 (37%), Positives = 40/70 (57%) Frame = +2 Query: 125 GHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHVVMAF 304 G + Q+EYA EAV++GS K++ ++L + +KI +D HV ++ Sbjct: 705 GRIHQIEYAMEAVKQGSATVALKSKTHAVIVALKRAPSELSAHQ--KKILPIDTHVGVSI 762 Query: 305 AGLTADARIL 334 AGLTADAR+L Sbjct: 763 AGLTADARLL 772 >UniRef50_Q8SQP9 Cluster: PROTEASOME REGULATORY SUBUNIT 8; n=1; Encephalitozoon cuniculi|Rep: PROTEASOME REGULATORY SUBUNIT 8 - Encephalitozoon cuniculi Length = 242 Score = 47.2 bits (107), Expect = 3e-04 Identities = 38/167 (22%), Positives = 69/167 (41%) Frame = +2 Query: 107 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 286 T+++ G + Q+ YAQ+A G T EK V+ L + KI + + Sbjct: 8 TIYTTTGQIDQLSYAQKAADSGDTCIGMKSKHGVVLLAEKPRVSPLYILESDEKIRKIGN 67 Query: 287 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 466 + + G+++D + + HK + T + Y+ + +T+ R Sbjct: 68 TIGVVCTGMSSDTFYVGCAIKDYVFHHKENFNEDPTPGMMKVYLNDIFHYFTRGINLRVL 127 Query: 467 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 G + L + DGS L T+ SG +KA G+ + ++ LEK Sbjct: 128 GANTLTSVYK-DGSFSLLHTDCSGKTLSYKAACIGKGTRRIKTELEK 173 >UniRef50_Q5KFP2 Cluster: Proteasome subunit beta type; n=3; Fungi/Metazoa group|Rep: Proteasome subunit beta type - Cryptococcus neoformans (Filobasidiella neoformans) Length = 272 Score = 46.8 bits (106), Expect = 4e-04 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 2/121 (1%) Frame = +2 Query: 248 EERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGL 427 + R RK+ L D VV+A G AD + R + + ++ + L+ I R I Sbjct: 58 QTRYARKVWQLTDKVVLATNGFAADGNNFVKRVKQRLEWYEHAHNKAMGLKSIARMIQ-- 115 Query: 428 KQKYTQSNGRR--PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFL 601 T G+R P+ + ++GG + DGS ++ +P G Y A G + ++ FL Sbjct: 116 ----TMLYGKRFFPYYVYNILGGIEEDGSGAVYSFDPVGSYEREACRAAGAAQSLIQPFL 171 Query: 602 E 604 + Sbjct: 172 D 172 >UniRef50_P28061 Cluster: Proteasome subunit beta precursor; n=4; Thermoplasmatales|Rep: Proteasome subunit beta precursor - Thermoplasma acidophilum Length = 211 Score = 44.8 bits (101), Expect = 0.002 Identities = 28/118 (23%), Positives = 56/118 (47%) Frame = +2 Query: 263 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 442 +K+ +D + M AGL DA++L+ + E + ++L + +E + ++ + + Sbjct: 40 KKLFQIDTYTGMTIAGLVGDAQVLVRYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVK 99 Query: 443 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYT 616 P+ + L+GG D +PH+F + +G E +TG + V LE Y+ Sbjct: 100 YM----PYMVQLLVGGIDT--APHVFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYS 151 >UniRef50_P22141 Cluster: Proteasome component C11; n=36; Ascomycota|Rep: Proteasome component C11 - Saccharomyces cerevisiae (Baker's yeast) Length = 198 Score = 44.4 bits (100), Expect = 0.002 Identities = 31/122 (25%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Frame = +2 Query: 278 LDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQS-NG 454 L H +M+FAG D Q Q + + + ++ + ++ ++ +Q+ +S Sbjct: 38 LSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAVSSFV---RQELAKSIRS 94 Query: 455 RRPFGISCLIGGFD-YDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVA 631 RRP+ ++ LIGG+D P L+Q + G E A G S L+ +Y D Sbjct: 95 RRPYQVNVLIGGYDKKKNKPELYQIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTT 154 Query: 632 TE 637 E Sbjct: 155 EE 156 >UniRef50_Q98RN2 Cluster: 26s proteasome SU A6; n=1; Guillardia theta|Rep: 26s proteasome SU A6 - Guillardia theta (Cryptomonas phi) Length = 235 Score = 43.6 bits (98), Expect = 0.004 Identities = 35/157 (22%), Positives = 66/157 (42%) Frame = +2 Query: 107 TVFSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDD 286 T+F DG +LQ+E+A + +G E K + + +D+ Sbjct: 6 TLFDSDGKILQLEFALKIPNQGKMIFSFKSINHSYIISEIHE--KKTNNKFFNRFYSIDN 63 Query: 287 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 466 ++ + +G+ DA+ + N K ++ ++EYI++ I+ T +RP+ Sbjct: 64 NIGLGISGIFFDAKKIFNFCVELNIKIKQAFKNFCSVEYISKKISEAFSNNTLKINQRPY 123 Query: 467 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRS 577 I+ I GF D P +F+ G+ K +G S Sbjct: 124 AINVFIIGFS-DKGPIIFEISTDGLMTYKKTCLSGSS 159 >UniRef50_A6R393 Cluster: Proteasome component C5; n=5; Ascomycota|Rep: Proteasome component C5 - Ajellomyces capsulatus NAm1 Length = 266 Score = 42.7 bits (96), Expect = 0.007 Identities = 26/106 (24%), Positives = 46/106 (43%) Frame = +2 Query: 287 HVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPF 466 H+V++ G AD R L R + +K P+++ + +A + S P+ Sbjct: 89 HLVLSVVGFAADGRALKERLDAIVKMYKYKHGKPMSVNACAQRLATI----LYSKRFFPY 144 Query: 467 GISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 604 + ++ G D DG L+ +P G Y A G +A + FL+ Sbjct: 145 YVHAILAGMDEDGKGALYSYDPVGSYEREYCRAAGAAASLIMPFLD 190 >UniRef50_Q23FB2 Cluster: Proteasome, putative; n=5; Oligohymenophorea|Rep: Proteasome, putative - Tetrahymena thermophila SB210 Length = 297 Score = 41.5 bits (93), Expect = 0.017 Identities = 23/95 (24%), Positives = 48/95 (50%) Frame = +2 Query: 224 KKSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEY 403 + S TVRKI ++D ++ AG AD + IEC+ ++L + V++ Sbjct: 93 RASQGSFDASETVRKIIEINDQLLGTMAGGAADCQFWEQYLAIECRKYQLQNREKVSVAA 152 Query: 404 ITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS 508 +R + + Y +++G + C++ G+D++G+ Sbjct: 153 ASRILINILYSY-RNHG---LSMGCMLTGWDHEGA 183 >UniRef50_A2BN27 Cluster: Proteasome beta; n=3; Desulfurococcales|Rep: Proteasome beta - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 212 Score = 41.5 bits (93), Expect = 0.017 Identities = 30/121 (24%), Positives = 56/121 (46%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 + +KI + D++ M AGL ADA++L +++ + +++ +Y++ + Sbjct: 44 KRTKKIIKITDYMAMTTAGLVADAQMLAEWLANHTHYYEIVNKRRMSIHAAAQYLSII-- 101 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 S P+ + L+GG YD P L+ + G E K ATG + T +E Y Sbjct: 102 --LHSAKFYPYIVQLLLGG--YDTQPRLYNIDWFGSVTEEKYVATGSGSPTAIGVIEDQY 157 Query: 614 T 616 + Sbjct: 158 S 158 >UniRef50_A1RX71 Cluster: Proteasome endopeptidase complex; n=1; Thermofilum pendens Hrk 5|Rep: Proteasome endopeptidase complex - Thermofilum pendens (strain Hrk 5) Length = 204 Score = 41.1 bits (92), Expect = 0.022 Identities = 32/120 (26%), Positives = 54/120 (45%) Frame = +2 Query: 263 RKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYT 442 +K+ + D + MA AGL AD + L + E + ++L + ++ + T +A L Sbjct: 37 KKVYRILDKMGMASAGLMADMQTLARIVEAEMRLYEL--DSNISPKVWT--VAKLLSYIL 92 Query: 443 QSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 P+ ++GG D +GS HL+ +P G E A G + +E NY D Sbjct: 93 YERRLFPYYAEIVVGGLDEEGS-HLYSLDPIGAIIEDDYVALGSGTQLAISIVESNYKKD 151 >UniRef50_Q9UXF3 Cluster: Proteasome subunit beta precursor; n=5; Sulfolobaceae|Rep: Proteasome subunit beta precursor - Sulfolobus solfataricus Length = 208 Score = 40.7 bits (91), Expect = 0.029 Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 5/174 (2%) Frame = +2 Query: 125 GHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKL-QEERTVRKICLLDDHVVMA 301 G+ LQ+E + KG+T ++++ A + VRK+ + D + + Sbjct: 2 GNELQLE---NKILKGTTTVGIRVNDGVILAADRRASAGFFVANKMVRKVLYITDKIGIT 58 Query: 302 FAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCL 481 AG AD + + + + + +T P++++ I +A + + P+ + L Sbjct: 59 TAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANV----LSATKYFPYIVQIL 114 Query: 482 IGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY----TADEVA 631 IGG YD P LF + G E ATG + LE Y T DE A Sbjct: 115 IGG--YDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAA 166 >UniRef50_O23370 Cluster: Cell wall protein like; n=15; Magnoliophyta|Rep: Cell wall protein like - Arabidopsis thaliana (Mouse-ear cress) Length = 428 Score = 40.3 bits (90), Expect = 0.038 Identities = 16/56 (28%), Positives = 31/56 (55%) Frame = +2 Query: 470 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTADEVATE 637 ++C + G+D + L+ ++PSG Y W+A A G + + + L+++Y D E Sbjct: 354 VACAVAGWDRNHGFQLYMSDPSGNYGGWQAAAVGANNQAAQSILKQDYKDDATREE 409 >UniRef50_Q966I8 Cluster: Proteasome subunit beta type; n=2; Caenorhabditis|Rep: Proteasome subunit beta type - Caenorhabditis elegans Length = 239 Score = 40.3 bits (90), Expect = 0.038 Identities = 31/157 (19%), Positives = 61/157 (38%), Gaps = 1/157 (0%) Frame = +2 Query: 146 YAQEAVRKGSTAXXXXXXXXXXXXXEKK-SVAKLQEERTVRKICLLDDHVVMAFAGLTAD 322 Y QE + G+T + + S R KI + D++V+ +G AD Sbjct: 15 YPQEEISTGTTLIAMEYNGGVVVGTDSRTSAGSFITSRATNKITPITDNMVVCRSGSAAD 74 Query: 323 ARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYD 502 + + + A+ + +T PVT+ ++ Y R S L+ G+D + Sbjct: 75 TQAIADIAKYHIDVYTMTENKPVTIYRSSQIFRQFLYNY-----REQLSASVLVAGWDEE 129 Query: 503 GSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 ++ G ++ A+G + V+ FL+ + Sbjct: 130 LGGQVYAIPIGGFVSRQRSTASGSGSTFVQGFLDSQW 166 >UniRef50_UPI0000499449 Cluster: proteasome beta subunit; n=1; Entamoeba histolytica HM-1:IMSS|Rep: proteasome beta subunit - Entamoeba histolytica HM-1:IMSS Length = 252 Score = 39.9 bits (89), Expect = 0.051 Identities = 24/119 (20%), Positives = 50/119 (42%) Frame = +2 Query: 257 TVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQK 436 +V+K + H++ AG AD +C+ +L + P+++ ++ +A + + Sbjct: 68 SVQKYIPITSHIIGTMAGGAADCAYWERELTRQCRLFELRNKPPISVAAASKMLANILYQ 127 Query: 437 YTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 Y N + +I G+D G PH+F E G+ + G + ++ Y Sbjct: 128 YRNYN----LSVGSMICGYDKTG-PHIFYVEDGGVRIPGHLFSVGSGSPYAVSLIDSEY 181 >UniRef50_Q8ZYF2 Cluster: Proteasome beta subunit; n=5; Thermoproteaceae|Rep: Proteasome beta subunit - Pyrobaculum aerophilum Length = 202 Score = 39.9 bits (89), Expect = 0.051 Identities = 28/119 (23%), Positives = 54/119 (45%) Frame = +2 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 KI +DDHV +G AD + +++ + +K+ + P+ + + Y++ L Y++ Sbjct: 34 KIWKIDDHVAATMSGGVADLQSVLSFLTLRAHEYKIEYKRPIPISALVNYMS-LILFYSR 92 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 + + +IGG D + L+ + G + K ATG + + LE Y D Sbjct: 93 P---YIYIVHSIIGGVDEEEGAVLYMVDWLGTVTKEKYIATGSGSPYAKGALEVGYRED 148 >UniRef50_Q8T8V8 Cluster: Proteasome subunit beta type; n=13; Neoptera|Rep: Proteasome subunit beta type - Drosophila melanogaster (Fruit fly) Length = 315 Score = 39.1 bits (87), Expect = 0.088 Identities = 29/123 (23%), Positives = 52/123 (42%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 +T+RKI L+D+++ AG AD EC+ H+L +T++ R I + Sbjct: 100 QTMRKIVELNDYMLGTLAGGAADCVYWDRVLAKECRLHQLRYRKRMTVDTAARIICNIST 159 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 +Y + ++ GFD +G P L + G+ + + G + L+ Y Sbjct: 160 EYKGMG----LVMGMMLAGFDDEG-PKLIYVDSEGMRSHGQVFSVGSGSPYALGVLDTGY 214 Query: 614 TAD 622 D Sbjct: 215 RYD 217 >UniRef50_A2DD57 Cluster: Proteasome subunit beta type; n=1; Trichomonas vaginalis G3|Rep: Proteasome subunit beta type - Trichomonas vaginalis G3 Length = 256 Score = 39.1 bits (87), Expect = 0.088 Identities = 31/128 (24%), Positives = 51/128 (39%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 +TV KI L +++ AG AD + + Q HK + P+T+ ++ + Sbjct: 82 QTVMKILPLAPNMIGTMAGGAADCQYWLRNLSRLIQLHKFRYQQPLTVAAASKILVNELY 141 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 +Y N I +I G+D G PH+F + G K + G + L+ Y Sbjct: 142 RYKGYN----LSIGSMICGYDNTG-PHIFYIDNHGSRIAGKRFSVGSGSTHAYGVLDTCY 196 Query: 614 TADEVATE 637 D E Sbjct: 197 REDMTKEE 204 >UniRef50_Q7QXH2 Cluster: GLP_14_13300_13022; n=1; Giardia lamblia ATCC 50803|Rep: GLP_14_13300_13022 - Giardia lamblia ATCC 50803 Length = 92 Score = 38.3 bits (85), Expect = 0.15 Identities = 29/71 (40%), Positives = 31/71 (43%) Frame = -3 Query: 285 SSKRHIFLTVRSSCNLATDFFSXXXXXXXXXXXXTAVDPFLTAS*AYSTCNKCPSGENTV 106 SS IF R SCNLA S TA P TA A ST +CPSG TV Sbjct: 4 SSTSKIFWEARGSCNLAVCLRSMASTMPAAERTATADVPRSTALCACSTWIRCPSGLKTV 63 Query: 105 MALSYRADMVK 73 SY D+ K Sbjct: 64 RDESYLPDIFK 74 >UniRef50_P23724 Cluster: Proteasome component C5; n=23; Fungi/Metazoa group|Rep: Proteasome component C5 - Saccharomyces cerevisiae (Baker's yeast) Length = 241 Score = 37.1 bits (82), Expect = 0.36 Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 3/110 (2%) Frame = +2 Query: 284 DHVVMAFAGLTADARILINRAQIECQSHKLTVEDP-VTLEYITRYIAGLKQKYTQSNGRR 460 D++VM+ G AD L+ R + + + D +++ R I L G+R Sbjct: 67 DNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLY------GKR 120 Query: 461 --PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 604 P+ + +I G D DG ++ +P G Y + A G +A + FL+ Sbjct: 121 FFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLD 170 >UniRef50_P40306 Cluster: Proteasome subunit beta type-10 precursor; n=28; Eukaryota|Rep: Proteasome subunit beta type-10 precursor - Homo sapiens (Human) Length = 273 Score = 36.7 bits (81), Expect = 0.47 Identities = 29/121 (23%), Positives = 47/121 (38%) Frame = +2 Query: 251 ERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLK 430 +++ KI + + AG+ ADA + + + H L+ + +TR L+ Sbjct: 67 DKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVASKMELHALSTGREPRVATVTRI---LR 123 Query: 431 QKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN 610 Q + G G S ++GG D G P L+ P G Y A G LE Sbjct: 124 QTLFRYQGH--VGASLIVGGVDLTG-PQLYGVHPHGSYSRLPFTALGSGQDAALAVLEDR 180 Query: 611 Y 613 + Sbjct: 181 F 181 >UniRef50_UPI000023D2A5 Cluster: hypothetical protein FG06803.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG06803.1 - Gibberella zeae PH-1 Length = 235 Score = 36.3 bits (80), Expect = 0.62 Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%) Frame = +2 Query: 278 LDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGR 457 L+ H ++AF+G D Q Q + + E ++ + ++ G + T R Sbjct: 43 LNKHTLLAFSGEAGDTVQFAEYIQRNAQLYSMRNESDLSPSALAHFVRG--ELATSLRSR 100 Query: 458 RPFGISCLIGGFD-YDGSPHLF 520 +P+ ++ L+GG D G P L+ Sbjct: 101 KPYNVNLLMGGVDPITGKPSLY 122 >UniRef50_Q1YM98 Cluster: Putative uncharacterized protein; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative uncharacterized protein - Aurantimonas sp. SI85-9A1 Length = 352 Score = 35.9 bits (79), Expect = 0.82 Identities = 20/73 (27%), Positives = 40/73 (54%) Frame = +2 Query: 230 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYIT 409 ++ ++ E T R + D H VMAFAGL +A +L R ++ C L + P +++ Sbjct: 64 ALTRIAGEETRRWLEAFDPHKVMAFAGLVLEACVLDERWRVACWRLDLDEKTP----HLS 119 Query: 410 RYIAGLKQKYTQS 448 ++ L+Q ++++ Sbjct: 120 VFVVPLRQSHSKT 132 >UniRef50_Q6CA23 Cluster: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome D of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 238 Score = 35.9 bits (79), Expect = 0.82 Identities = 25/113 (22%), Positives = 48/113 (42%) Frame = +2 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 K+ + D++++ G +AD LI + + + P+ ++ R I Q Sbjct: 67 KVFDVGDNILVTANGFSADGDALIENIKQHVELYHYQNNKPLKVQSCARAI----QHMLY 122 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLE 604 + P+ + +I G D +G ++ +P G Y A G +A V FL+ Sbjct: 123 NKRFFPYYVHTIIAGLDEEGKGAVYSYDPVGSYEREFCRAGGSAASLVMPFLD 175 >UniRef50_A2F8W4 Cluster: Family T1, proteasome beta subunit, threonine peptidase; n=2; Trichomonas vaginalis G3|Rep: Family T1, proteasome beta subunit, threonine peptidase - Trichomonas vaginalis G3 Length = 191 Score = 35.5 bits (78), Expect = 1.1 Identities = 28/116 (24%), Positives = 47/116 (40%) Frame = +2 Query: 266 KICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQ 445 +I LDD +A +G T D L Q +K ++ + + +I K + Sbjct: 34 RIAQLDDRHALAMSGETGDCLQLSEYLQGNVALYKFRNGVELSSDALAHFIRHTMAKAVR 93 Query: 446 SNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 + P+ ++ L+ G YDG PHL+ + G A G V +K+Y Sbjct: 94 KS---PYEVNMLLSG--YDGKPHLYFMDYLGTLQSIPYGAQGYCQYFVMSVFDKHY 144 >UniRef50_A2DSN0 Cluster: Cellulosomal scaffoldin anchoring protein, putative; n=1; Trichomonas vaginalis G3|Rep: Cellulosomal scaffoldin anchoring protein, putative - Trichomonas vaginalis G3 Length = 637 Score = 33.9 bits (74), Expect = 3.3 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = -1 Query: 548 HNIYQKVQFGTSVVNHHSRILLSNTKYQMVDDHCSEY 438 H ++Q V F S +NH+ + ++++ KY + +HCS Y Sbjct: 36 HYLFQYVTF--SNINHYGKYIINSAKYMLKMEHCSMY 70 >UniRef50_Q00826 Cluster: Probable proteasome subunit beta type-2; n=2; Filobasidiella neoformans|Rep: Probable proteasome subunit beta type-2 - Cryptococcus neoformans (Filobasidiella neoformans) Length = 224 Score = 33.9 bits (74), Expect = 3.3 Identities = 22/99 (22%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = +2 Query: 227 KSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYI 406 +S+ +++ + K+ L H+ MAF+G D + + + + P+ Sbjct: 23 RSIVRMKSDEN--KLKTLGPHLAMAFSGEPGDTNNFAEYIERNMRLYNIRNHFPLLPPAA 80 Query: 407 TRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGS-PHLF 520 + ++ + +S R P+ ++ L+GGFD S PHL+ Sbjct: 81 SAWVRRTLAEAIRS--RHPYAVNLLLGGFDTTTSKPHLY 117 >UniRef50_A4RRA7 Cluster: Proteasome subunit beta type; n=2; Ostreococcus|Rep: Proteasome subunit beta type - Ostreococcus lucimarinus CCE9901 Length = 246 Score = 33.5 bits (73), Expect = 4.4 Identities = 20/120 (16%), Positives = 47/120 (39%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 R K+C L+D +M +G AD L + H++ +++ ++ + + Sbjct: 46 RASDKMCALNDRTIMCRSGSAADTEALAGYVRNIVSQHEMELDEIADVKTVATIANQIGY 105 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 + +N R ++GG+D ++ G + + G + + FL+ + Sbjct: 106 QNKGANRGRGLSAYTIVGGWDKRRGSQVYACTAGGNMIKERWTTDGSGSTYIWGFLDSGW 165 >UniRef50_Q5CU00 Cluster: Pre3p/proteasome regulatory subunit beta type 6, NTN hydrolase fold; n=3; Cryptosporidium|Rep: Pre3p/proteasome regulatory subunit beta type 6, NTN hydrolase fold - Cryptosporidium parvum Iowa II Length = 248 Score = 33.1 bits (72), Expect = 5.8 Identities = 30/168 (17%), Positives = 65/168 (38%), Gaps = 1/168 (0%) Frame = +2 Query: 122 DGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXE-KKSVAKLQEERTVRKICLLDDHVVM 298 D ++++++ + G+T + + S + R RKI + D V M Sbjct: 35 DQKIMELDFLNGEIETGTTIVALKYKDGLVLAADGRTSTGPIIAFRAARKITQITDKVFM 94 Query: 299 AFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGISC 478 +G AD +I+ + Q H+L + + + +A + + + N + Sbjct: 95 CRSGSAADTQIISRYVRRIVQDHELETGEDTKV----KSVASVARLISYQN-KEHLLADM 149 Query: 479 LIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNYTAD 622 +I G D +G +F+ G E +G + + L+ Y ++ Sbjct: 150 IIAGMDPNGEFKVFRIPLGGTLIEGSYAISGSGSGYIYSMLDSKYHSE 197 >UniRef50_A0CW62 Cluster: Proteasome subunit beta type; n=3; Oligohymenophorea|Rep: Proteasome subunit beta type - Paramecium tetraurelia Length = 194 Score = 33.1 bits (72), Expect = 5.8 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 2/130 (1%) Frame = +2 Query: 230 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYIT 409 S+ K++E T KI LDDH + +G AD +I ++H L + Sbjct: 24 SILKIKE--TEDKILKLDDHKIFGISGEGADRNSF---GEIVHKNHCLIRYKTGGYMNLQ 78 Query: 410 RYIAGLKQKYTQSNGRR--PFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAK 583 ++ Y Q+ R P + L+GG D DG+P L+ + G + A G + Sbjct: 79 ETAHFVRSMYAQAIRSRDGPHQCNGLLGGVDSDGTPSLYWLDYLGSLQKITRGAQGYANY 138 Query: 584 TVREFLEKNY 613 + L+ Y Sbjct: 139 FLLGLLDNQY 148 >UniRef50_Q9VNA5 Cluster: Probable proteasome subunit beta type-4; n=3; Sophophora|Rep: Probable proteasome subunit beta type-4 - Drosophila melanogaster (Fruit fly) Length = 268 Score = 33.1 bits (72), Expect = 5.8 Identities = 25/119 (21%), Positives = 55/119 (46%), Gaps = 5/119 (4%) Frame = +2 Query: 230 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARIL---INRAQIE--CQSHKLTVEDPVT 394 S + + + ++ ++ ++++ +G AD + + I++ IE C + ++ Sbjct: 78 SYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNIEMKPKSL 137 Query: 395 LEYITRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATG 571 ++TR + Y + + P I ++GG D +G+P+L + G YE ATG Sbjct: 138 ASWMTRVL------YNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATG 190 >UniRef50_A0P0V6 Cluster: Putative uncharacterized protein; n=2; Stappia aggregata IAM 12614|Rep: Putative uncharacterized protein - Stappia aggregata IAM 12614 Length = 82 Score = 32.7 bits (71), Expect = 7.7 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 6/58 (10%) Frame = +2 Query: 473 SCLI-GGF--DYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKN---YTADEV 628 +CL+ GF D DG+P LF+ +P G W + R+ + +R F++KN +T D++ Sbjct: 22 ACLVRAGFAQDKDGTP-LFKYDPCGSEAFWDKQSIARNGEGLRLFVDKNGQVWTEDQI 78 >UniRef50_Q9XG34 Cluster: 26S proteasome IOTA SU; n=1; Guillardia theta|Rep: 26S proteasome IOTA SU - Guillardia theta (Cryptomonas phi) Length = 237 Score = 32.7 bits (71), Expect = 7.7 Identities = 31/144 (21%), Positives = 51/144 (35%) Frame = +2 Query: 113 FSPDGHLLQVEYAQEAVRKGSTAXXXXXXXXXXXXXEKKSVAKLQEERTVRKICLLDDHV 292 F+P G + Q+EYA + +KGS K E I LDD Sbjct: 10 FAPSGRIFQIEYAVKK-KKGSICIGIKNNSFLIFLLYKSQ--NSSSESNESDIIFLDDKT 66 Query: 293 VMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQKYTQSNGRRPFGI 472 GL D I + ++ + Y+++ I Q T + RP Sbjct: 67 GCLCNGLAIDVYEQIEEIKNIFFNYYSQYRSKIQTSYLSKLITFKNQYLTHYSFSRPRST 126 Query: 473 SCLIGGFDYDGSPHLFQTEPSGIY 544 + +I D + LF+ + +G + Sbjct: 127 NLIIFNLDNELGGQLFKGDNTGSF 150 >UniRef50_Q8T8U1 Cluster: Proteasome subunit beta type; n=1; Drosophila melanogaster|Rep: Proteasome subunit beta type - Drosophila melanogaster (Fruit fly) Length = 215 Score = 32.7 bits (71), Expect = 7.7 Identities = 32/132 (24%), Positives = 52/132 (39%) Frame = +2 Query: 227 KSVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYI 406 KS L +E VRK + D+ +M+ AG D + +K+T +T+ Sbjct: 23 KSAMWLDDE--VRKTHRISDYCMMSTAGDGGDCLKFSDFILRNMDLYKITNGYDLTVRGA 80 Query: 407 TRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKT 586 +I Y +S+ F +S L+GG+D P L + G + G + Sbjct: 81 VHFIRRHLSAYLKSDCT--FQVSLLVGGYDLTSGPELHYIDYLGNSVPVRYGGHGAAMNF 138 Query: 587 VREFLEKNYTAD 622 LE+ Y D Sbjct: 139 CTPILEEFYKPD 150 >UniRef50_Q59F72 Cluster: Proteasome alpha 6 subunit variant; n=1; Homo sapiens|Rep: Proteasome alpha 6 subunit variant - Homo sapiens (Human) Length = 80 Score = 32.7 bits (71), Expect = 7.7 Identities = 14/46 (30%), Positives = 24/46 (52%) Frame = +2 Query: 470 ISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEK 607 + ++ G D + P +++ +P+G Y +KA A G FLEK Sbjct: 7 LGMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEK 52 >UniRef50_Q5A9K1 Cluster: Possible intermediate filament protein Mdm1p; n=2; Candida albicans|Rep: Possible intermediate filament protein Mdm1p - Candida albicans (Yeast) Length = 1032 Score = 32.7 bits (71), Expect = 7.7 Identities = 12/27 (44%), Positives = 17/27 (62%) Frame = -2 Query: 499 IVESSYQTRNTKWSTTIALSIFLFETC 419 ++ S YQ NT+ + L IF+FETC Sbjct: 960 VIRSLYQQSNTRQEAKVLLEIFIFETC 986 >UniRef50_Q0UWV2 Cluster: Predicted protein; n=4; Pezizomycotina|Rep: Predicted protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 260 Score = 32.7 bits (71), Expect = 7.7 Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = +2 Query: 230 SVAKLQEERTVRKICLLDDHVVMAFAGLTADARILINRAQ-IECQSHKLTVEDPVTLEYI 406 S+A+ + + +RK +D VV+ F G +D + L ++ + + E + + + Sbjct: 64 SLARFTDVKRLRKF---NDEVVVGFGGDVSDMQYLDRLLNSLDIRETYSSNETALNAKNL 120 Query: 407 TRYIAGLKQKYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKT 586 Y+A K Y + + P LI G D + P L + G + + ATG A Sbjct: 121 HTYLA--KVMYNRRSKFDPLWNHLLIAGMDGESKPFLASADLLGTTFSSPSLATGFGAHL 178 Query: 587 VREFLEKNYTADEVATE 637 + L + DE + E Sbjct: 179 AQPIL-RTILPDEASVE 194 >UniRef50_O23717 Cluster: Proteasome subunit beta type-5-A precursor; n=13; Viridiplantae|Rep: Proteasome subunit beta type-5-A precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 274 Score = 32.7 bits (71), Expect = 7.7 Identities = 24/123 (19%), Positives = 53/123 (43%) Frame = +2 Query: 254 RTVRKICLLDDHVVMAFAGLTADARILINRAQIECQSHKLTVEDPVTLEYITRYIAGLKQ 433 ++V+KI ++ +++ AG AD + I+C+ H+L + +++ ++ +A + Sbjct: 86 QSVKKIIEINPYMLGTMAGGAADCQFWHRNLGIKCRLHELANKRRISVSGASKLLANMLY 145 Query: 434 KYTQSNGRRPFGISCLIGGFDYDGSPHLFQTEPSGIYYEWKANATGRSAKTVREFLEKNY 613 Y + +I G+D G P L+ + G + + G + L+ Y Sbjct: 146 SYRGMG----LSVGTMIAGWDETG-PGLYYVDNEGGRLKGDRFSVGSGSPYAYGVLDSGY 200 Query: 614 TAD 622 D Sbjct: 201 KYD 203 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 596,488,493 Number of Sequences: 1657284 Number of extensions: 11897216 Number of successful extensions: 27466 Number of sequences better than 10.0: 154 Number of HSP's better than 10.0 without gapping: 26543 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 27355 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 47711253245 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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