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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= S06A01NCLL0023_P05
         (250 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

S90469-1|AAB21814.1|  676|Homo sapiens cytochrome P450 reductase...   109   1e-24
DQ640499-1|ABF70199.1|  677|Homo sapiens P450 (cytochrome) oxido...   109   1e-24
BC034277-1|AAH34277.1|  680|Homo sapiens P450 (cytochrome) oxido...   109   1e-24
AF258341-1|AAG09798.1|  677|Homo sapiens NADPH-cytochrome P450 r...   109   1e-24
AB209874-1|BAD93111.1|  686|Homo sapiens Hypothetical protein DK...   109   1e-24
AB051763-1|BAB18572.1|  677|Homo sapiens NADPH-cytochrome P-450 ...   109   1e-24
AF051164-1|AAC83554.1| 1147|Homo sapiens heart muscle inducible ...    32   0.39 
AF049656-1|AAC83553.1| 1147|Homo sapiens inducible nitric oxide ...    32   0.39 
U31466-1|AAB49040.1| 1433|Homo sapiens nitric oxide synthase pro...    31   0.89 
U17327-1|AAA62405.1| 1434|Homo sapiens neuronal nitric oxide syn...    31   0.89 
U17326-1|AAB60654.1| 1554|Homo sapiens neuronal nitric oxide syn...    31   0.89 
L02881-1|AAA36376.1| 1433|Homo sapiens nitric oxide synthase pro...    31   0.89 
D16408-1|BAA03895.1| 1434|Homo sapiens nitric oxide synthase pro...    31   0.89 
AY445095-1|AAR07069.1| 1434|Homo sapiens nitric oxide synthase 1...    31   0.89 
X76303-1|CAA53950.1| 1203|Homo sapiens endothelial nitric oxide ...    30   1.6  
M95296-1|AAA36372.1| 1203|Homo sapiens nitric oxide synthase pro...    30   1.6  
M93718-1|AAA36364.1| 1203|Homo sapiens nitric oxide synthase pro...    30   1.6  
L26914-1|AAA36374.1| 1203|Homo sapiens nitric oxide synthase pro...    30   1.6  
L10709-1|AAA36365.1| 1203|Homo sapiens nitric oxide synthase pro...    30   1.6  
D26607-1|BAA05652.1| 1204|Homo sapiens endothelial nitric oxide ...    30   1.6  
BC069465-1|AAH69465.1| 1203|Homo sapiens nitric oxide synthase 3...    30   1.6  
BC063294-1|AAH63294.1| 1203|Homo sapiens nitric oxide synthase 3...    30   1.6  
AK223636-1|BAD97356.1| 1203|Homo sapiens nitric oxide synthase 3...    30   1.6  
AF519768-1|AAM74944.1| 1203|Homo sapiens nitric oxide synthase 3...    30   1.6  
AF400594-1|AAK83389.1| 1203|Homo sapiens endothelial nitric oxid...    30   1.6  

>S90469-1|AAB21814.1|  676|Homo sapiens cytochrome P450 reductase
           protein.
          Length = 676

 Score =  109 bits (263), Expect = 1e-24
 Identities = 48/79 (60%), Positives = 65/79 (82%)
 Frame = +2

Query: 11  DAKNPFLAQIKVNKELHKGGDRSCLHVELDISDSKMRYEAGDHVAVYPINDTKLVERLGE 190
           DAKNPFLA +  N++L++G +R  +H+ELDISDSK+RYE+GDHVAVYP ND+ LV +LG+
Sbjct: 276 DAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGK 335

Query: 191 LTGANLDEIFSLMNTDQES 247
           + GA+LD + SL N D+ES
Sbjct: 336 ILGADLDVVMSLNNLDEES 354


>DQ640499-1|ABF70199.1|  677|Homo sapiens P450 (cytochrome)
           oxidoreductase protein.
          Length = 677

 Score =  109 bits (263), Expect = 1e-24
 Identities = 48/79 (60%), Positives = 65/79 (82%)
 Frame = +2

Query: 11  DAKNPFLAQIKVNKELHKGGDRSCLHVELDISDSKMRYEAGDHVAVYPINDTKLVERLGE 190
           DAKNPFLA +  N++L++G +R  +H+ELDISDSK+RYE+GDHVAVYP ND+ LV +LG+
Sbjct: 277 DAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGK 336

Query: 191 LTGANLDEIFSLMNTDQES 247
           + GA+LD + SL N D+ES
Sbjct: 337 ILGADLDVVMSLNNLDEES 355


>BC034277-1|AAH34277.1|  680|Homo sapiens P450 (cytochrome)
           oxidoreductase protein.
          Length = 680

 Score =  109 bits (263), Expect = 1e-24
 Identities = 48/79 (60%), Positives = 65/79 (82%)
 Frame = +2

Query: 11  DAKNPFLAQIKVNKELHKGGDRSCLHVELDISDSKMRYEAGDHVAVYPINDTKLVERLGE 190
           DAKNPFLA +  N++L++G +R  +H+ELDISDSK+RYE+GDHVAVYP ND+ LV +LG+
Sbjct: 280 DAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGK 339

Query: 191 LTGANLDEIFSLMNTDQES 247
           + GA+LD + SL N D+ES
Sbjct: 340 ILGADLDVVMSLNNLDEES 358


>AF258341-1|AAG09798.1|  677|Homo sapiens NADPH-cytochrome P450
           reductase protein.
          Length = 677

 Score =  109 bits (263), Expect = 1e-24
 Identities = 48/79 (60%), Positives = 65/79 (82%)
 Frame = +2

Query: 11  DAKNPFLAQIKVNKELHKGGDRSCLHVELDISDSKMRYEAGDHVAVYPINDTKLVERLGE 190
           DAKNPFLA +  N++L++G +R  +H+ELDISDSK+RYE+GDHVAVYP ND+ LV +LG+
Sbjct: 277 DAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGK 336

Query: 191 LTGANLDEIFSLMNTDQES 247
           + GA+LD + SL N D+ES
Sbjct: 337 ILGADLDVVMSLNNLDEES 355


>AB209874-1|BAD93111.1|  686|Homo sapiens Hypothetical protein
           DKFZp686G04235 variant protein.
          Length = 686

 Score =  109 bits (263), Expect = 1e-24
 Identities = 48/79 (60%), Positives = 65/79 (82%)
 Frame = +2

Query: 11  DAKNPFLAQIKVNKELHKGGDRSCLHVELDISDSKMRYEAGDHVAVYPINDTKLVERLGE 190
           DAKNPFLA +  N++L++G +R  +H+ELDISDSK+RYE+GDHVAVYP ND+ LV +LG+
Sbjct: 286 DAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGK 345

Query: 191 LTGANLDEIFSLMNTDQES 247
           + GA+LD + SL N D+ES
Sbjct: 346 ILGADLDVVMSLNNLDEES 364


>AB051763-1|BAB18572.1|  677|Homo sapiens NADPH-cytochrome P-450
           reductase protein.
          Length = 677

 Score =  109 bits (263), Expect = 1e-24
 Identities = 48/79 (60%), Positives = 65/79 (82%)
 Frame = +2

Query: 11  DAKNPFLAQIKVNKELHKGGDRSCLHVELDISDSKMRYEAGDHVAVYPINDTKLVERLGE 190
           DAKNPFLA +  N++L++G +R  +H+ELDISDSK+RYE+GDHVAVYP ND+ LV +LG+
Sbjct: 277 DAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGK 336

Query: 191 LTGANLDEIFSLMNTDQES 247
           + GA+LD + SL N D+ES
Sbjct: 337 ILGADLDVVMSLNNLDEES 355


>AF051164-1|AAC83554.1| 1147|Homo sapiens heart muscle inducible
           nitric oxide synthase protein.
          Length = 1147

 Score = 31.9 bits (69), Expect = 0.39
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +2

Query: 14  AKNPFLAQIKVNKELH-KGGDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLG 187
           AKN F  ++K  + L  +   R+ L V+L    S+   Y  G+H+ ++P N T LV+ + 
Sbjct: 726 AKNVFTMRLKSLQNLQSEKSSRTTLLVQLTFEGSRGPSYLPGEHLGIFPGNQTALVQGIL 785

Query: 188 E 190
           E
Sbjct: 786 E 786


>AF049656-1|AAC83553.1| 1147|Homo sapiens inducible nitric oxide
           synthase protein.
          Length = 1147

 Score = 31.9 bits (69), Expect = 0.39
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +2

Query: 14  AKNPFLAQIKVNKELH-KGGDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLG 187
           AKN F  ++K  + L  +   R+ L V+L    S+   Y  G+H+ ++P N T LV+ + 
Sbjct: 726 AKNVFAMRLKSLQNLQSEKSSRTTLLVQLTFEGSRGPSYLPGEHLGIFPGNQTALVQGIL 785

Query: 188 E 190
           E
Sbjct: 786 E 786


>U31466-1|AAB49040.1| 1433|Homo sapiens nitric oxide synthase protein.
          Length = 1433

 Score = 30.7 bits (66), Expect = 0.89
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 74   RSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLGE 190
            RS + V L  + S+ ++Y+ GDH+ V+P N   LV  L E
Sbjct: 1014 RSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIE 1053


>U17327-1|AAA62405.1| 1434|Homo sapiens neuronal nitric oxide synthase
            protein.
          Length = 1434

 Score = 30.7 bits (66), Expect = 0.89
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 74   RSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLGE 190
            RS + V L  + S+ ++Y+ GDH+ V+P N   LV  L E
Sbjct: 1015 RSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIE 1054


>U17326-1|AAB60654.1| 1554|Homo sapiens neuronal nitric oxide synthase
            protein.
          Length = 1554

 Score = 30.7 bits (66), Expect = 0.89
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 74   RSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLGE 190
            RS + V L  + S+ ++Y+ GDH+ V+P N   LV  L E
Sbjct: 1015 RSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIE 1054


>L02881-1|AAA36376.1| 1433|Homo sapiens nitric oxide synthase protein.
          Length = 1433

 Score = 30.7 bits (66), Expect = 0.89
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 74   RSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLGE 190
            RS + V L  + S+ ++Y+ GDH+ V+P N   LV  L E
Sbjct: 1014 RSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIE 1053


>D16408-1|BAA03895.1| 1434|Homo sapiens nitric oxide synthase protein.
          Length = 1434

 Score = 30.7 bits (66), Expect = 0.89
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 74   RSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLGE 190
            RS + V L  + S+ ++Y+ GDH+ V+P N   LV  L E
Sbjct: 1015 RSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIE 1054


>AY445095-1|AAR07069.1| 1434|Homo sapiens nitric oxide synthase 1
            (neuronal) protein.
          Length = 1434

 Score = 30.7 bits (66), Expect = 0.89
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = +2

Query: 74   RSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERLGE 190
            RS + V L  + S+ ++Y+ GDH+ V+P N   LV  L E
Sbjct: 1015 RSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIE 1054


>X76303-1|CAA53950.1| 1203|Homo sapiens endothelial nitric oxide
           synthase protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>M95296-1|AAA36372.1| 1203|Homo sapiens nitric oxide synthase
           protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>M93718-1|AAA36364.1| 1203|Homo sapiens nitric oxide synthase
           protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>L26914-1|AAA36374.1| 1203|Homo sapiens nitric oxide synthase
           protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>L10709-1|AAA36365.1| 1203|Homo sapiens nitric oxide synthase
           protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>D26607-1|BAA05652.1| 1204|Homo sapiens endothelial nitric oxide
           synthase protein.
          Length = 1204

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>BC069465-1|AAH69465.1| 1203|Homo sapiens nitric oxide synthase 3
           (endothelial cell) protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>BC063294-1|AAH63294.1| 1203|Homo sapiens nitric oxide synthase 3
           (endothelial cell) protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>AK223636-1|BAD97356.1| 1203|Homo sapiens nitric oxide synthase 3
           (endothelial cell) variant protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>AF519768-1|AAM74944.1| 1203|Homo sapiens nitric oxide synthase 3
           (endothelial cell) protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


>AF400594-1|AAK83389.1| 1203|Homo sapiens endothelial nitric oxide
           synthase protein.
          Length = 1203

 Score = 29.9 bits (64), Expect = 1.6
 Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
 Frame = +2

Query: 26  FLAQIKVNKELHKG-GDRSCLHVELDISDSK-MRYEAGDHVAVYPINDTKLVERL 184
           F A I+  + L      R+ + V LD    + ++Y+ GDH+ V P N   LVE L
Sbjct: 759 FQATIRSVENLQSSKSTRATILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEAL 813


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 31,340,440
Number of Sequences: 237096
Number of extensions: 454427
Number of successful extensions: 1078
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 1051
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1078
length of database: 76,859,062
effective HSP length: 60
effective length of database: 62,633,302
effective search space used: 1377932644
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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