Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0014_P12
(621 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC000038-1|AAH00038.1| 423|Homo sapiens sphingomyelin phosphodi... 200 2e-51
AL109947-3|CAI23338.1| 423|Homo sapiens sphingomyelin phosphodi... 200 2e-51
AJ222801-1|CAA10995.1| 423|Homo sapiens neutral sphingomyelinas... 200 2e-51
AL109947-4|CAI23340.1| 77|Homo sapiens sphingomyelin phosphodi... 88 2e-17
DQ424899-1|ABD83664.1| 638|Homo sapiens sphingomyelin phosphodi... 34 0.35
BC112238-1|AAI12239.1| 655|Homo sapiens sphingomyelin phosphodi... 34 0.35
AJ250460-1|CAB92964.1| 655|Homo sapiens neutral sphingomyelinas... 34 0.35
AK127601-1|BAC87052.1| 415|Homo sapiens protein ( Homo sapiens ... 33 1.1
>BC000038-1|AAH00038.1| 423|Homo sapiens sphingomyelin
phosphodiesterase 2, neutral membrane (neutral
sphingomyelinase) protein.
Length = 423
Score = 200 bits (489), Expect = 2e-51
Identities = 89/178 (50%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +2
Query: 86 LNIFTLNCWGIPFVSKNRKERFQAISKYLVESSHNIVCLQEVWSEKDYLFLKETLKTVLP 265
L IF LNCWGIP++SK+R +R + + +L + S ++ L+EVWSE+D+ +L++ L P
Sbjct: 9 LRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYP 68
Query: 266 YSHYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCGDR 445
+H+F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK VGL +
Sbjct: 69 AAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGM 128
Query: 446 LVNVYCTHLHAEYH-VDDMYLAHRVLQAYSTAEFVKLTTAPADVSILAGDLNTAPGDI 616
++N Y THLHAEY+ D+YLAHRV QA+ A+F+ T+ ADV +L GDLN P D+
Sbjct: 129 VLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDL 186
>AL109947-3|CAI23338.1| 423|Homo sapiens sphingomyelin
phosphodiesterase 2, neutral membrane (neutral
sphingomyelinase) protein.
Length = 423
Score = 200 bits (489), Expect = 2e-51
Identities = 89/178 (50%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +2
Query: 86 LNIFTLNCWGIPFVSKNRKERFQAISKYLVESSHNIVCLQEVWSEKDYLFLKETLKTVLP 265
L IF LNCWGIP++SK+R +R + + +L + S ++ L+EVWSE+D+ +L++ L P
Sbjct: 9 LRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYP 68
Query: 266 YSHYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCGDR 445
+H+F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK VGL +
Sbjct: 69 AAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGM 128
Query: 446 LVNVYCTHLHAEYH-VDDMYLAHRVLQAYSTAEFVKLTTAPADVSILAGDLNTAPGDI 616
++N Y THLHAEY+ D+YLAHRV QA+ A+F+ T+ ADV +L GDLN P D+
Sbjct: 129 VLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDL 186
>AJ222801-1|CAA10995.1| 423|Homo sapiens neutral sphingomyelinase
protein.
Length = 423
Score = 200 bits (489), Expect = 2e-51
Identities = 89/178 (50%), Positives = 124/178 (69%), Gaps = 1/178 (0%)
Frame = +2
Query: 86 LNIFTLNCWGIPFVSKNRKERFQAISKYLVESSHNIVCLQEVWSEKDYLFLKETLKTVLP 265
L IF LNCWGIP++SK+R +R + + +L + S ++ L+EVWSE+D+ +L++ L P
Sbjct: 9 LRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYP 68
Query: 266 YSHYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCGDR 445
+H+F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK VGL +
Sbjct: 69 AAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGM 128
Query: 446 LVNVYCTHLHAEYH-VDDMYLAHRVLQAYSTAEFVKLTTAPADVSILAGDLNTAPGDI 616
++N Y THLHAEY+ D+YLAHRV QA+ A+F+ T+ ADV +L GDLN P D+
Sbjct: 129 VLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDL 186
>AL109947-4|CAI23340.1| 77|Homo sapiens sphingomyelin
phosphodiesterase 2, neutral membrane (neutral
sphingomyelinase) protein.
Length = 77
Score = 88.2 bits (209), Expect = 2e-17
Identities = 37/70 (52%), Positives = 49/70 (70%)
Frame = +2
Query: 263 PYSHYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCGD 442
P +H+F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK VGL +
Sbjct: 2 PAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSG 61
Query: 443 RLVNVYCTHL 472
++N Y TH+
Sbjct: 62 MVLNAYVTHV 71
>DQ424899-1|ABD83664.1| 638|Homo sapiens sphingomyelin
phosphodiesterase 3 protein.
Length = 638
Score = 34.3 bits (75), Expect = 0.35
Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 16/113 (14%)
Frame = +2
Query: 188 NIVCLQEVWSEKDYLFLKETLKTVLPYSHY---FYS-------GVLGSGLCVFSKWVIQD 337
+ +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417
Query: 338 VFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCG-----DRLVN-VYCTHLHA 478
V +H +P +K + D KG +++ G R+V + CTHLHA
Sbjct: 418 VAYHCYP-----NKC-NDDALASKGALFLKVQVGSTPQDQRIVGYIACTHLHA 464
>BC112238-1|AAI12239.1| 655|Homo sapiens sphingomyelin
phosphodiesterase 3, neutral membrane protein.
Length = 655
Score = 34.3 bits (75), Expect = 0.35
Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 16/113 (14%)
Frame = +2
Query: 188 NIVCLQEVWSEKDYLFLKETLKTVLPYSHY---FYS-------GVLGSGLCVFSKWVIQD 337
+ +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417
Query: 338 VFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCG-----DRLVN-VYCTHLHA 478
V +H +P +K + D KG +++ G R+V + CTHLHA
Sbjct: 418 VAYHCYP-----NKC-NDDALASKGALFLKVQVGSTPQDQRIVGYIACTHLHA 464
>AJ250460-1|CAB92964.1| 655|Homo sapiens neutral sphingomyelinase
II protein.
Length = 655
Score = 34.3 bits (75), Expect = 0.35
Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 16/113 (14%)
Frame = +2
Query: 188 NIVCLQEVWSEKDYLFLKETLKTVLPYSHY---FYS-------GVLGSGLCVFSKWVIQD 337
+ +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417
Query: 338 VFFHQWPLNGYIHKIHHGDWFGGKGVGLCRIKCG-----DRLVN-VYCTHLHA 478
V +H +P +K + D KG +++ G R+V + CTHLHA
Sbjct: 418 VAYHCYP-----NKC-NDDALASKGALFLKVQVGSTPQDQRIVGYIACTHLHA 464
>AK127601-1|BAC87052.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ45698 fis, clone FEBRA2017811. ).
Length = 415
Score = 32.7 bits (71), Expect = 1.1
Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Frame = -2
Query: 494 HLHDIPHVNVY-NKH*QVCLHI*CGTNQHLCLQTNLHDESYVYTHS 360
H H HV+++ N H C HI T +C T++H ++++TH+
Sbjct: 114 HAHIHIHVHIHMNIHTHTCTHIYTCTYTVVCTHTHMHIYTHMHTHT 159
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,288,464
Number of Sequences: 237096
Number of extensions: 2065597
Number of successful extensions: 4413
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4258
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4409
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6691573490
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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