Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0014_F03
(601 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene ... 251 2e-66
M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase p... 251 2e-66
BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle... 251 2e-66
BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein. 251 2e-66
BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle... 251 2e-66
BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle... 251 2e-66
BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle... 251 2e-66
BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle... 251 2e-66
AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle... 251 2e-66
AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isofo... 251 2e-66
X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein. 248 1e-65
BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein. 248 1e-65
M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein. 244 1e-64
U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L isoe... 244 2e-64
U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R isoe... 244 2e-64
BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver ... 244 2e-64
AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver ... 244 2e-64
AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver... 244 2e-64
AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver... 244 2e-64
AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein. 244 2e-64
D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein. 240 2e-63
S60712-1|AAB26262.1| 67|Homo sapiens R-type pyruvate kinase pr... 105 9e-23
AF025439-1|AAC39559.1| 164|Homo sapiens Opa-interacting protein... 103 6e-22
AF157692-1|AAD47248.1| 56|Homo sapiens pyruvate kinase M2 prot... 62 1e-09
AF242584-1|AAF65764.1| 55|Homo sapiens pyruvate kinase M2 prot... 60 6e-09
AF185280-1|AAF01766.1| 56|Homo sapiens pyruvate kinase M2 prot... 60 8e-09
AF157693-1|AAD47249.1| 47|Homo sapiens frameshifted pyruvate k... 30 5.4
>M26252-1|AAA36672.1| 531|Homo sapiens protein ( Human TCB gene
encoding cytosolic thyroid hormone-binding protein,
complete cds. ).
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>M23725-1|AAA36449.1| 531|Homo sapiens M2-type pyruvate kinase
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQNLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>BC035198-1|AAH35198.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>BC019265-1|AAH19265.2| 343|Homo sapiens PKM2 protein protein.
Length = 343
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 99 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 158
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 159 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 218
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 219 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 267
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 71 GEKGKNIKIISKIENHEGVRRFDEI 95
>BC012811-1|AAH12811.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>BC007952-1|AAH07952.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>BC007640-1|AAH07640.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>BC000481-1|AAH00481.3| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>AY352517-1|AAQ15274.1| 531|Homo sapiens pyruvate kinase, muscle
protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>AK222927-1|BAD96647.1| 531|Homo sapiens pyruvate kinase 3 isoform
1 variant protein.
Length = 531
Score = 251 bits (614), Expect = 2e-66
Identities = 122/169 (72%), Positives = 136/169 (80%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>X56494-1|CAA39849.1| 531|Homo sapiens pyruvate kinase protein.
Length = 531
Score = 248 bits (607), Expect = 1e-65
Identities = 121/169 (71%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKP TRAE S
Sbjct: 287 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPPPTRAEGS 346
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAAI+H QLF EL
Sbjct: 347 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITS 406
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP +TA+ AVEAS KC + AI+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 407 DPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTR 455
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 259 GEKGKNIKIISKIENHEGVRRFDEI 283
>BC094767-1|AAH94767.1| 366|Homo sapiens PKM2 protein protein.
Length = 366
Score = 248 bits (607), Expect = 1e-65
Identities = 120/169 (71%), Positives = 139/169 (82%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCNR GKPVICATQMLESM+KKPR TRAE S
Sbjct: 122 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGS 181
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKGDYPLE V I +EAEAA++HR+LF ELV +
Sbjct: 182 DVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHST 241
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
D + A+ +VEAS KCLA+A++V+T SG+S H +++YRPR PIIAVTR
Sbjct: 242 DLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTR 290
Score = 39.5 bits (88), Expect = 0.009
Identities = 18/25 (72%), Positives = 20/25 (80%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
GE+ KNIKIISKIENH G+ DEI
Sbjct: 94 GEKGKNIKIISKIENHEGVRRFDEI 118
>M15465-1|AAA60104.1| 543|Homo sapiens pyruvate kinase protein.
Length = 543
Score = 244 bits (598), Expect = 1e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 299 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 358
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 359 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHRIAREAEAAVYHRQLFEELRRAAPLSR 418
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 419 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 467
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 271 GPEGHGIKIISKIENHEGVKRFDEI 295
>U47654-2|AAA92536.1| 566|Homo sapiens pyruvate kinase PK-L
isoenzyme protein.
Length = 566
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 322 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 381
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 382 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 441
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 442 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 490
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 294 GPEGHGIKIISKIENHEGVKRFDEI 318
>U47654-1|AAA92535.1| 587|Homo sapiens pyruvate kinase PK-R
isoenzyme protein.
Length = 587
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 343 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 402
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 403 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 462
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 463 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 511
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 315 GPEGHGIKIISKIENHEGVKRFDEI 339
>BC025737-1|AAH25737.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 389
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 390 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 449
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 450 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 498
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 302 GPEGHGIKIISKIENHEGVKRFDEI 326
>AY316591-1|AAP69527.1| 574|Homo sapiens pyruvate kinase, liver and
RBC protein.
Length = 574
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 389
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 390 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 449
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 450 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 498
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 302 GPEGHGIKIISKIENHEGVKRFDEI 326
>AL713999-33|CAI95102.1| 585|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 585
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 341 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 400
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 401 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 460
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 461 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 509
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 313 GPEGHGIKIISKIENHEGVKRFDEI 337
>AL713999-32|CAI95101.1| 565|Homo sapiens pyruvate kinase, liver
and RBC protein.
Length = 565
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 321 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 380
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 381 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 440
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 441 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 489
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 293 GPEGHGIKIISKIENHEGVKRFDEI 317
>AB015983-1|BAA31706.1| 574|Homo sapiens pyruvate kinase L protein.
Length = 574
Score = 244 bits (596), Expect = 2e-64
Identities = 117/169 (69%), Positives = 135/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ KPR TRAE S
Sbjct: 330 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETS 389
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 390 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 449
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 450 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 498
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 302 GPEGHGIKIISKIENHEGVKRFDEI 326
>D13243-1|BAA02515.1| 599|Homo sapiens pyruvate kinase L protein.
Length = 599
Score = 240 bits (588), Expect = 2e-63
Identities = 116/169 (68%), Positives = 134/169 (79%)
Frame = +1
Query: 94 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRATRAEIS 273
SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKPV+CATQMLESM+ K R TRAE S
Sbjct: 355 SDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETS 414
Query: 274 DVANAILDGADCVMLSGETAKGDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPI 453
DVANA+LDGADC+MLSGETAKG++P+E V I +EAEAA++HRQLF EL
Sbjct: 415 DVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSR 474
Query: 454 DPAHSTAIAAVEASTKCLASAIVVITTSGKSXHLLSKYRPRCPIIAVTR 600
DP TAI AVEA+ KC A+AI+V+TT+G+S LLS+YRPR +IAVTR
Sbjct: 475 DPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 523
Score = 33.1 bits (72), Expect = 0.77
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +3
Query: 9 GEQRKNIKIISKIENHPGMVNLDEI 83
G + IKIISKIENH G+ DEI
Sbjct: 327 GPEGHGIKIISKIENHEGVKRFDEI 351
>S60712-1|AAB26262.1| 67|Homo sapiens R-type pyruvate kinase
protein.
Length = 67
Score = 105 bits (253), Expect = 9e-23
Identities = 49/67 (73%), Positives = 56/67 (83%)
Frame = +1
Query: 199 KPVICATQMLESMVKKPRATRAEISDVANAILDGADCVMLSGETAKGDYPLECVLTMANI 378
KPV CATQMLESM+ KPR TRAE SDVANA+LDGADC+MLSGETAKG++P+E V I
Sbjct: 1 KPVFCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAI 60
Query: 379 CKEAEAA 399
+EAEAA
Sbjct: 61 AREAEAA 67
>AF025439-1|AAC39559.1| 164|Homo sapiens Opa-interacting protein
OIP3 protein.
Length = 164
Score = 103 bits (246), Expect = 6e-22
Identities = 50/88 (56%), Positives = 61/88 (69%)
Frame = +1
Query: 337 GDYPLECVLTMANICKEAEAAIWHRQLFNELVAEVTAPIDPAHSTAIAAVEASTKCLASA 516
GDYPLE V I +EAEAAI+H QLF EL DP +TA+ AVEAS KC + A
Sbjct: 1 GDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGA 60
Query: 517 IVVITTSGKSXHLLSKYRPRCPIIAVTR 600
I+V+T SG+S H +++YRPR PIIAVTR
Sbjct: 61 IIVLTKSGRSAHQVARYRPRAPIIAVTR 88
>AF157692-1|AAD47248.1| 56|Homo sapiens pyruvate kinase M2
protein.
Length = 56
Score = 62.1 bits (144), Expect = 1e-09
Identities = 30/56 (53%), Positives = 38/56 (67%)
Frame = +1
Query: 376 ICKEAEAAIWHRQLFNELVAEVTAPIDPAHSTAIAAVEASTKCLASAIVVITTSGK 543
I +EAEAAI+H QLF EL DP +TA+ AVEAS KC + AI+V+T SG+
Sbjct: 1 IAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGR 56
>AF242584-1|AAF65764.1| 55|Homo sapiens pyruvate kinase M2
protein.
Length = 55
Score = 60.1 bits (139), Expect = 6e-09
Identities = 29/55 (52%), Positives = 37/55 (67%)
Frame = +1
Query: 376 ICKEAEAAIWHRQLFNELVAEVTAPIDPAHSTAIAAVEASTKCLASAIVVITTSG 540
I +EAEAAI+H QLF EL DP +TA+ AVEAS +C + AI+V+T SG
Sbjct: 1 IAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFRCCSGAIIVLTKSG 55
>AF185280-1|AAF01766.1| 56|Homo sapiens pyruvate kinase M2
protein.
Length = 56
Score = 59.7 bits (138), Expect = 8e-09
Identities = 29/56 (51%), Positives = 38/56 (67%)
Frame = +1
Query: 376 ICKEAEAAIWHRQLFNELVAEVTAPIDPAHSTAIAAVEASTKCLASAIVVITTSGK 543
I +EAEAAI++ QLF EL DP +TA+ AVEAS KC + AI+V+T SG+
Sbjct: 1 IAREAEAAIYYLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGR 56
>AF157693-1|AAD47249.1| 47|Homo sapiens frameshifted pyruvate
kinase M2 protein.
Length = 47
Score = 30.3 bits (65), Expect = 5.4
Identities = 15/28 (53%), Positives = 17/28 (60%)
Frame = +1
Query: 376 ICKEAEAAIWHRQLFNELVAEVTAPIDP 459
I +EAEAAI+H QLF EL DP
Sbjct: 1 IAREAEAAIYHLQLFEELRRLAPITSDP 28
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 81,603,194
Number of Sequences: 237096
Number of extensions: 1643346
Number of successful extensions: 8331
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 8065
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8320
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6297951520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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