Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0014_D18
(569 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L24559-1|AAA16459.1| 598|Homo sapiens DNA polymerase alpha prot... 55 2e-07
CR456737-1|CAG33018.1| 598|Homo sapiens POLA2 protein. 55 2e-07
BC002990-1|AAH02990.1| 598|Homo sapiens polymerase (DNA directe... 55 2e-07
BC001347-1|AAH01347.1| 598|Homo sapiens polymerase (DNA directe... 55 2e-07
BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, t... 33 0.54
AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1... 33 0.54
AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein... 33 0.54
AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease ... 33 0.54
AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, t... 33 0.54
BC150253-1|AAI50254.1| 1011|Homo sapiens SEMA6D protein protein. 31 2.9
AK022831-1|BAB14264.1| 464|Homo sapiens protein ( Homo sapiens ... 31 2.9
AK022747-1|BAB14221.1| 451|Homo sapiens protein ( Homo sapiens ... 31 2.9
AF389430-1|AAM69453.1| 1011|Homo sapiens semaphorin 6D isoform 1... 31 2.9
AF389429-1|AAM69452.1| 1073|Homo sapiens semaphorin 6D isoform 4... 31 2.9
AF389428-1|AAM69451.1| 1017|Homo sapiens semaphorin 6D isoform 3... 31 2.9
AF389427-1|AAM69450.1| 998|Homo sapiens semaphorin 6D isoform 2... 31 2.9
AB040912-1|BAA96003.2| 1022|Homo sapiens KIAA1479 protein protein. 31 2.9
AF265555-1|AAF75772.1| 4829|Homo sapiens ubiquitin-conjugating B... 30 6.6
>L24559-1|AAA16459.1| 598|Homo sapiens DNA polymerase alpha
protein.
Length = 598
Score = 54.8 bits (126), Expect = 2e-07
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Frame = +2
Query: 23 ASEELVTEQFQFLGIDVQKEVLRKCVSLCEEYDVDAESLIEQWIAFSLNNLNGASPNLEN 202
AS + + E+ Q G+D ++ ++ K V LC +Y + E ++ + IAF + + E
Sbjct: 3 ASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAF-CTSTHKVGLTSEI 61
Query: 203 LDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSDNEVLSNYMAV----TP 370
L+ F + SKR S+ + + + + + + E+L N +
Sbjct: 62 LNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQ 121
Query: 371 KRA-KIENEPATQNE---------LCPSTYSPTVV-SVKYASRNNMGTVVHSYG 499
KRA P T+ L PS++SP+ S KY SR+N G VV S+G
Sbjct: 122 KRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFG 175
>CR456737-1|CAG33018.1| 598|Homo sapiens POLA2 protein.
Length = 598
Score = 54.8 bits (126), Expect = 2e-07
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Frame = +2
Query: 23 ASEELVTEQFQFLGIDVQKEVLRKCVSLCEEYDVDAESLIEQWIAFSLNNLNGASPNLEN 202
AS + + E+ Q G+D ++ ++ K V LC +Y + E ++ + IAF + + E
Sbjct: 3 ASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAF-CTSTHKVGLTSEI 61
Query: 203 LDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSDNEVLSNYMAV----TP 370
L+ F + SKR S+ + + + + + + E+L N +
Sbjct: 62 LNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQ 121
Query: 371 KRA-KIENEPATQNE---------LCPSTYSPTVV-SVKYASRNNMGTVVHSYG 499
KRA P T+ L PS++SP+ S KY SR+N G VV S+G
Sbjct: 122 KRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFG 175
>BC002990-1|AAH02990.1| 598|Homo sapiens polymerase (DNA directed),
alpha 2 (70kD subunit) protein.
Length = 598
Score = 54.8 bits (126), Expect = 2e-07
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Frame = +2
Query: 23 ASEELVTEQFQFLGIDVQKEVLRKCVSLCEEYDVDAESLIEQWIAFSLNNLNGASPNLEN 202
AS + + E+ Q G+D ++ ++ K V LC +Y + E ++ + IAF + + E
Sbjct: 3 ASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAF-CTSTHKVGLTSEI 61
Query: 203 LDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSDNEVLSNYMAV----TP 370
L+ F + SKR S+ + + + + + + E+L N +
Sbjct: 62 LNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQ 121
Query: 371 KRA-KIENEPATQNE---------LCPSTYSPTVV-SVKYASRNNMGTVVHSYG 499
KRA P T+ L PS++SP+ S KY SR+N G VV S+G
Sbjct: 122 KRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFG 175
>BC001347-1|AAH01347.1| 598|Homo sapiens polymerase (DNA directed),
alpha 2 (70kD subunit) protein.
Length = 598
Score = 54.8 bits (126), Expect = 2e-07
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Frame = +2
Query: 23 ASEELVTEQFQFLGIDVQKEVLRKCVSLCEEYDVDAESLIEQWIAFSLNNLNGASPNLEN 202
AS + + E+ Q G+D ++ ++ K V LC +Y + E ++ + IAF + + E
Sbjct: 3 ASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAF-CTSTHKVGLTSEI 61
Query: 203 LDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSDNEVLSNYMAV----TP 370
L+ F + SKR S+ + + + + + + E+L N +
Sbjct: 62 LNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQ 121
Query: 371 KRA-KIENEPATQNE---------LCPSTYSPTVV-SVKYASRNNMGTVVHSYG 499
KRA P T+ L PS++SP+ S KY SR+N G VV S+G
Sbjct: 122 KRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFG 175
>BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, type
C1 protein.
Length = 1278
Score = 33.5 bits (73), Expect = 0.54
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Frame = +2
Query: 305 YGGPVSAQSDNEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP-----TVVSVKYASRN 469
+G P+ Q ++VL +A+ A +NE T ++C + SP T++SV +N
Sbjct: 431 FGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQN 490
Query: 470 NMGTVVHSYGDE 505
+ + H GD+
Sbjct: 491 SHSVLDHKKGDD 502
>AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1
protein protein.
Length = 1278
Score = 33.5 bits (73), Expect = 0.54
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Frame = +2
Query: 305 YGGPVSAQSDNEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP-----TVVSVKYASRN 469
+G P+ Q ++VL +A+ A +NE T ++C + SP T++SV +N
Sbjct: 431 FGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQN 490
Query: 470 NMGTVVHSYGDE 505
+ + H GD+
Sbjct: 491 SHSVLDHKKGDD 502
>AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein
protein.
Length = 1278
Score = 33.5 bits (73), Expect = 0.54
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Frame = +2
Query: 305 YGGPVSAQSDNEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP-----TVVSVKYASRN 469
+G P+ Q ++VL +A+ A +NE T ++C + SP T++SV +N
Sbjct: 431 FGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQN 490
Query: 470 NMGTVVHSYGDE 505
+ + H GD+
Sbjct: 491 SHSVLDHKKGDD 502
>AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease
protein protein.
Length = 1278
Score = 33.5 bits (73), Expect = 0.54
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Frame = +2
Query: 305 YGGPVSAQSDNEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP-----TVVSVKYASRN 469
+G P+ Q ++VL +A+ A +NE T ++C + SP T++SV +N
Sbjct: 431 FGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQN 490
Query: 470 NMGTVVHSYGDE 505
+ + H GD+
Sbjct: 491 SHSVLDHKKGDD 502
>AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, type
C1 variant protein.
Length = 1289
Score = 33.5 bits (73), Expect = 0.54
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Frame = +2
Query: 305 YGGPVSAQSDNEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP-----TVVSVKYASRN 469
+G P+ Q ++VL +A+ A +NE T ++C + SP T++SV +N
Sbjct: 442 FGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQN 501
Query: 470 NMGTVVHSYGDE 505
+ + H GD+
Sbjct: 502 SHSVLDHKKGDD 513
>BC150253-1|AAI50254.1| 1011|Homo sapiens SEMA6D protein protein.
Length = 1011
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 778 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 837
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 838 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 870
>AK022831-1|BAB14264.1| 464|Homo sapiens protein ( Homo sapiens
cDNA FLJ12769 fis, clone NT2RP2001581. ).
Length = 464
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 231 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 290
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 291 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 323
>AK022747-1|BAB14221.1| 451|Homo sapiens protein ( Homo sapiens
cDNA FLJ12685 fis, clone NT2RM4002493. ).
Length = 451
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 218 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 277
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 278 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 310
>AF389430-1|AAM69453.1| 1011|Homo sapiens semaphorin 6D isoform 1
protein.
Length = 1011
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 778 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 837
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 838 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 870
>AF389429-1|AAM69452.1| 1073|Homo sapiens semaphorin 6D isoform 4
protein.
Length = 1073
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 840 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 899
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 900 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 932
>AF389428-1|AAM69451.1| 1017|Homo sapiens semaphorin 6D isoform 3
protein.
Length = 1017
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 784 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 843
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 844 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 876
>AF389427-1|AAM69450.1| 998|Homo sapiens semaphorin 6D isoform 2
protein.
Length = 998
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 765 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 824
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 825 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 857
>AB040912-1|BAA96003.2| 1022|Homo sapiens KIAA1479 protein protein.
Length = 1022
Score = 31.1 bits (67), Expect = 2.9
Identities = 23/94 (24%), Positives = 38/94 (40%)
Frame = +2
Query: 155 AFSLNNLNGASPNLENLDLFVRKEFSKRTSRTNAPGKETTQMVTGTCLTVYGGPVSAQSD 334
+FS +N + A L+N+D + K SKR R + + T + P + D
Sbjct: 789 SFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGD 848
Query: 335 NEVLSNYMAVTPKRAKIENEPATQNELCPSTYSP 436
++ + + P + E P N S YSP
Sbjct: 849 IQMAHQNLMLDPMGSMSEVPPKVPNREA-SLYSP 881
>AF265555-1|AAF75772.1| 4829|Homo sapiens ubiquitin-conjugating
BIR-domain enzyme APOLLON protein.
Length = 4829
Score = 29.9 bits (64), Expect = 6.6
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Frame = +2
Query: 53 QFLGIDVQKEVLRKCVSLCEEYDVDAESLIEQWIAFSLNNLNGASPNLEN-LDLFV 217
Q + + K S+ + + V ESL++ W+ SLN + +S N EN D+F+
Sbjct: 2604 QLSSVPMLNVCFNKLFSMLQVHHVQLESLLQLWLTLSLN--SSSSGNKENGADIFL 2657
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,654,126
Number of Sequences: 237096
Number of extensions: 1635557
Number of successful extensions: 5048
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4231
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5044
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5816287018
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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