Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0014_C19
(411 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 77 3e-14
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 77 3e-14
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 77 3e-14
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 77 3e-14
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 77 3e-14
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 77 3e-14
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 77 3e-14
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 77 3e-14
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 74 2e-13
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 71 2e-12
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 66 4e-11
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 66 4e-11
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 66 4e-11
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 66 4e-11
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 53 4e-07
X98507-1|CAA67131.1| 1028|Homo sapiens myosin I beta protein. 31 1.5
AK127658-1|BAC87076.1| 626|Homo sapiens protein ( Homo sapiens ... 29 7.9
AK091802-1|BAC03750.1| 447|Homo sapiens protein ( Homo sapiens ... 29 7.9
AK074157-1|BAB84983.1| 414|Homo sapiens FLJ00230 protein protein. 29 7.9
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 76.6 bits (180), Expect = 3e-14
Identities = 35/48 (72%), Positives = 40/48 (83%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 32.7 bits (71), Expect = 0.49
Identities = 15/24 (62%), Positives = 16/24 (66%)
Frame = +2
Query: 218 IVEMDGDEMTRIIWATN**KAYFP 289
+VEM GDEMTRIIW K FP
Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFP 33
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 74.1 bits (174), Expect = 2e-13
Identities = 34/48 (70%), Positives = 39/48 (81%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLI PYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 26 IKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 73
Score = 31.5 bits (68), Expect = 1.1
Identities = 12/14 (85%), Positives = 13/14 (92%)
Frame = +2
Query: 218 IVEMDGDEMTRIIW 259
+VEM GDEMTRIIW
Sbjct: 10 VVEMQGDEMTRIIW 23
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 70.9 bits (166), Expect = 2e-12
Identities = 32/44 (72%), Positives = 37/44 (84%)
Frame = +3
Query: 279 LIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
LIFPYV+LD YDLG+ +RDAT+DQVT DAA AI KHNVG+KC
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKC 44
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 66.1 bits (154), Expect = 4e-11
Identities = 29/48 (60%), Positives = 37/48 (77%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KC
Sbjct: 66 IKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKC 113
Score = 44.8 bits (101), Expect = 1e-04
Identities = 18/30 (60%), Positives = 21/30 (70%)
Frame = +2
Query: 170 HSRNYGTAKRVLATNPIVEMDGDEMTRIIW 259
H R + KR+ P+VEMDGDEMTRIIW
Sbjct: 34 HPRRHYADKRIKVAKPVVEMDGDEMTRIIW 63
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 66.1 bits (154), Expect = 4e-11
Identities = 29/48 (60%), Positives = 37/48 (77%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KC
Sbjct: 66 IKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKC 113
Score = 41.9 bits (94), Expect = 8e-04
Identities = 17/28 (60%), Positives = 20/28 (71%)
Frame = +2
Query: 176 RNYGTAKRVLATNPIVEMDGDEMTRIIW 259
R + KR+ P+VEMDGDEMTRIIW
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIW 63
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 66.1 bits (154), Expect = 4e-11
Identities = 29/48 (60%), Positives = 37/48 (77%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KC
Sbjct: 66 IKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKC 113
Score = 41.9 bits (94), Expect = 8e-04
Identities = 17/28 (60%), Positives = 20/28 (71%)
Frame = +2
Query: 176 RNYGTAKRVLATNPIVEMDGDEMTRIIW 259
R + KR+ P+VEMDGDEMTRIIW
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIW 63
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 66.1 bits (154), Expect = 4e-11
Identities = 29/48 (60%), Positives = 37/48 (77%)
Frame = +3
Query: 267 INEKLIFPYVKLDCLYYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
I EKLI P+V + Y+DLGLP+RD TDDQVTID+A A K++V +KC
Sbjct: 66 IKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKC 113
Score = 41.9 bits (94), Expect = 8e-04
Identities = 17/28 (60%), Positives = 20/28 (71%)
Frame = +2
Query: 176 RNYGTAKRVLATNPIVEMDGDEMTRIIW 259
R + KR+ P+VEMDGDEMTRIIW
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIW 63
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 52.8 bits (121), Expect = 4e-07
Identities = 22/33 (66%), Positives = 28/33 (84%)
Frame = +3
Query: 312 YYDLGLPHRDATDDQVTIDAAHAILKHNVGIKC 410
Y+DLGLP+RD TDDQVTID+A A K++V +KC
Sbjct: 48 YFDLGLPNRDQTDDQVTIDSALATQKYSVAVKC 80
>X98507-1|CAA67131.1| 1028|Homo sapiens myosin I beta protein.
Length = 1028
Score = 31.1 bits (67), Expect = 1.5
Identities = 14/39 (35%), Positives = 22/39 (56%)
Frame = +2
Query: 131 KKLLKYVSELTPIHSRNYGTAKRVLATNPIVEMDGDEMT 247
KKLL++ +E P R R+L +NP++E G+ T
Sbjct: 116 KKLLQFYAETCPAPQRGGAVRDRLLQSNPVLEAFGNAKT 154
>AK127658-1|BAC87076.1| 626|Homo sapiens protein ( Homo sapiens
cDNA FLJ45756 fis, clone MESAN2009156. ).
Length = 626
Score = 28.7 bits (61), Expect = 7.9
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = -3
Query: 262 SPNYAGHLISIHFNNWISSQNP 197
SP +AG+L+ HF NW +P
Sbjct: 126 SPYHAGNLLQRHFTNWTKPTSP 147
>AK091802-1|BAC03750.1| 447|Homo sapiens protein ( Homo sapiens
cDNA FLJ34483 fis, clone HLUNG2004154. ).
Length = 447
Score = 28.7 bits (61), Expect = 7.9
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = -3
Query: 262 SPNYAGHLISIHFNNWISSQNP 197
SP +AG+L+ HF NW +P
Sbjct: 276 SPYHAGNLLQRHFTNWTKPTSP 297
>AK074157-1|BAB84983.1| 414|Homo sapiens FLJ00230 protein protein.
Length = 414
Score = 28.7 bits (61), Expect = 7.9
Identities = 10/22 (45%), Positives = 14/22 (63%)
Frame = -3
Query: 262 SPNYAGHLISIHFNNWISSQNP 197
SP +AG+L+ HF NW +P
Sbjct: 172 SPYHAGNLLQRHFTNWTKPTSP 193
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,032,575
Number of Sequences: 237096
Number of extensions: 1194605
Number of successful extensions: 1870
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 1811
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1870
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3030544982
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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