Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0012_L05
(414 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 130 2e-30
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 130 2e-30
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 130 2e-30
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 130 2e-30
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 129 4e-30
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 129 4e-30
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 129 4e-30
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 129 4e-30
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 129 4e-30
AJ417593-1|CAD10391.2| 4169|Homo sapiens ALMS1 protein protein. 30 3.5
L42451-1|AAC42010.1| 407|Homo sapiens pyruvate dehydrogenase ki... 29 8.1
BC130277-1|AAI30278.1| 1444|Homo sapiens phosphoinositide-3-kina... 29 8.1
BC063137-1|AAH63137.1| 407|Homo sapiens pyruvate dehydrogenase ... 29 8.1
BC040478-1|AAH40478.1| 407|Homo sapiens pyruvate dehydrogenase ... 29 8.1
BC005811-1|AAH05811.1| 407|Homo sapiens pyruvate dehydrogenase ... 29 8.1
AJ000008-1|CAA03853.1| 1448|Homo sapiens PI3-kinase protein. 29 8.1
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 130 bits (314), Expect = 2e-30
Identities = 56/83 (67%), Positives = 71/83 (85%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPLI 259
QKT+ YGHFGR FPWE P+ L+
Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 130 bits (314), Expect = 2e-30
Identities = 56/83 (67%), Positives = 71/83 (85%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPLI 259
QKT+ YGHFGR FPWE P+ L+
Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 130 bits (314), Expect = 2e-30
Identities = 56/83 (67%), Positives = 71/83 (85%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPLI 259
QKT+ YGHFGR FPWE P+ L+
Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 130 bits (314), Expect = 2e-30
Identities = 56/83 (67%), Positives = 71/83 (85%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGVAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPLI 259
QKT+ YGHFGR FPWE P+ L+
Sbjct: 372 QKTACYGHFGRSEFPWEVPRKLV 394
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 129 bits (311), Expect = 4e-30
Identities = 55/82 (67%), Positives = 71/82 (86%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IVKKNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPL 256
Q+T+ YGHFGR+ FPWE PK L
Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 129 bits (311), Expect = 4e-30
Identities = 55/82 (67%), Positives = 71/82 (86%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IVKKNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPL 256
Q+T+ YGHFGR+ FPWE PK L
Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 129 bits (311), Expect = 4e-30
Identities = 55/82 (67%), Positives = 71/82 (86%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IVKKNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPL 256
Q+T+ YGHFGR+ FPWE PK L
Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 129 bits (311), Expect = 4e-30
Identities = 55/82 (67%), Positives = 71/82 (86%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IVKKNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPL 256
Q+T+ YGHFGR+ FPWE PK L
Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 129 bits (311), Expect = 4e-30
Identities = 55/82 (67%), Positives = 71/82 (86%)
Frame = +2
Query: 11 RRCMVQVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNLRAPIY 190
RR +VQV+YAIGV+ PLSI++F YGTS K++++LL IVKKNFDLRPG IV++L+L+ PIY
Sbjct: 312 RRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIY 371
Query: 191 QKTSTYGHFGREGFPWESPKPL 256
Q+T+ YGHFGR+ FPWE PK L
Sbjct: 372 QRTAAYGHFGRDSFPWEVPKKL 393
>AJ417593-1|CAD10391.2| 4169|Homo sapiens ALMS1 protein protein.
Length = 4169
Score = 29.9 bits (64), Expect = 3.5
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Frame = +2
Query: 2 HEGRRCMV--QVAYAIGVAEPLSITVFDYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNL 175
H+ R C + +V AI +P+S S + +QL + KK + + K L
Sbjct: 4090 HQNRMCPLPKRVFLAIQKNKPISKKEM-IQRSKRIYEQLPEVQKKREEEKRKSEYKSYRL 4148
Query: 176 RAPIYQKTSTYGHFGREGFPWE 241
RA +Y+K T GR+ PW+
Sbjct: 4149 RAQLYKKRVTNQLLGRK-VPWD 4169
>L42451-1|AAC42010.1| 407|Homo sapiens pyruvate dehydrogenase
kinase protein.
Length = 407
Score = 28.7 bits (61), Expect = 8.1
Identities = 13/41 (31%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +2
Query: 56 PLSITVF-DYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNL 175
PLS+ F D+G+S+ ++ + +++ +R I+KE+NL
Sbjct: 30 PLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINL 70
>BC130277-1|AAI30278.1| 1444|Homo sapiens phosphoinositide-3-kinase,
class 2, gamma polypeptide protein.
Length = 1444
Score = 28.7 bits (61), Expect = 8.1
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Frame = -2
Query: 251 AWGSPTGTLPGQSVRKYLFFDISALVGSIL*QFYPVAGQSSSLQWR-EAVVVFCAKCRSR 75
A G T + P Q +RK + L+ L ++ P Q+ +W E+ +V RS
Sbjct: 723 ALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRS- 781
Query: 74 IR*LRVALQLQWRMR 30
++ ++VA +L W ++
Sbjct: 782 LQSIQVAHRLYWLLK 796
>BC063137-1|AAH63137.1| 407|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 2 protein.
Length = 407
Score = 28.7 bits (61), Expect = 8.1
Identities = 13/41 (31%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +2
Query: 56 PLSITVF-DYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNL 175
PLS+ F D+G+S+ ++ + +++ +R I+KE+NL
Sbjct: 30 PLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINL 70
>BC040478-1|AAH40478.1| 407|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 2 protein.
Length = 407
Score = 28.7 bits (61), Expect = 8.1
Identities = 13/41 (31%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +2
Query: 56 PLSITVF-DYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNL 175
PLS+ F D+G+S+ ++ + +++ +R I+KE+NL
Sbjct: 30 PLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINL 70
>BC005811-1|AAH05811.1| 407|Homo sapiens pyruvate dehydrogenase
kinase, isozyme 2 protein.
Length = 407
Score = 28.7 bits (61), Expect = 8.1
Identities = 13/41 (31%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Frame = +2
Query: 56 PLSITVF-DYGTSHKTQQQLLSIVKKNFDLRPGKIVKELNL 175
PLS+ F D+G+S+ ++ + +++ +R I+KE+NL
Sbjct: 30 PLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINL 70
>AJ000008-1|CAA03853.1| 1448|Homo sapiens PI3-kinase protein.
Length = 1448
Score = 28.7 bits (61), Expect = 8.1
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Frame = -2
Query: 251 AWGSPTGTLPGQSVRKYLFFDISALVGSIL*QFYPVAGQSSSLQWR-EAVVVFCAKCRSR 75
A G T + P Q +RK + L+ L ++ P Q+ +W E+ +V RS
Sbjct: 724 ALGLLTSSFPDQEIRKVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPLVQLLLHRS- 782
Query: 74 IR*LRVALQLQWRMR 30
++ ++VA +L W ++
Sbjct: 783 LQSIQVAHRLYWLLK 797
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 65,456,508
Number of Sequences: 237096
Number of extensions: 1377227
Number of successful extensions: 6858
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 6816
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6858
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3087725076
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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