Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0011_N04
(607 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 82 1e-15
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 82 1e-15
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 82 1e-15
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 82 1e-15
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 82 1e-15
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 82 1e-15
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 82 1e-15
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 82 1e-15
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 82 1e-15
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 82 1e-15
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 82 1e-15
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 82 1e-15
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 82 1e-15
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 82 1e-15
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 82 1e-15
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 80 5e-15
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 79 9e-15
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 69 1e-11
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 55 2e-07
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 55 2e-07
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 55 2e-07
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 45 2e-04
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 43 7e-04
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 43 7e-04
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 41 0.003
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 41 0.003
M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary... 36 0.11
M16764-1|AAA88099.1| 286|Homo sapiens pulmonary surfactant-asso... 36 0.11
X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate activ... 36 0.15
BC039729-1|AAH39729.1| 516|Homo sapiens RIOK3 protein protein. 31 2.4
BC028360-1|AAH28360.1| 424|Homo sapiens RIO kinase 3 (yeast) pr... 31 2.4
AF013591-1|AAC26080.1| 519|Homo sapiens homolog of the Aspergil... 31 2.4
J05500-2|AAA60578.1| 2106|Homo sapiens SPTB protein. 29 9.6
J05500-1|AAA60579.1| 2137|Homo sapiens SPTB protein. 29 9.6
AK127156-1|BAC86859.1| 204|Homo sapiens protein ( Homo sapiens ... 29 9.6
AB209415-1|BAD92652.1| 2332|Homo sapiens spectrin, beta, erythro... 29 9.6
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 273 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 331
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 332 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 391
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 392 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 445
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 395 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 454
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 455 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 489
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 37.1 bits (82), Expect = 0.048
Identities = 37/163 (22%), Positives = 65/163 (39%), Gaps = 29/163 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + K ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSEIAI 253
Query: 379 ALLVQ-EIDPSSVCPAIGICPQVEEV--------------------------KH-VTINS 474
+++ + P +C +G C +V+E+ KH V S
Sbjct: 254 QMMMHMDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKS 313
Query: 475 D*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
D C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 314 D-VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 355
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 37.9 bits (84), Expect = 0.027
Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + K ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 274 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 332
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 333 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 392
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 393 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 446
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 396 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 455
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 456 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 490
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 38.3 bits (85), Expect = 0.021
Identities = 38/164 (23%), Positives = 66/164 (40%), Gaps = 30/164 (18%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + K ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADISKNYISQYSEIAI 253
Query: 379 ALLV--QEIDPSSVCPAIGICPQVEEV--------------------------KH-VTIN 471
+++ Q+ P +C +G C +V+E+ KH V
Sbjct: 254 QMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAK 313
Query: 472 SD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
SD C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 314 SD-VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 356
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 274 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 332
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 333 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 392
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 393 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 446
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 396 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 455
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 456 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 490
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 30/164 (18%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLV--QEIDPSSVCPAIGICPQVEEV--------------------------KH-VTIN 471
+++ Q+ P +C +G C +V+E+ KH V
Sbjct: 254 QMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAK 313
Query: 472 SD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
SD C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 314 SD-VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 356
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIRMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 82.2 bits (194), Expect = 1e-15
Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 277 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 335
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG +++++L++E+ P VC + +C
Sbjct: 336 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS 395
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 396 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 449
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 399 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 458
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 459 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 493
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 66 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 125
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 126 GEMSRPGEVCSALNLCESLQK 146
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 30/164 (18%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 197 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 256
Query: 379 ALLV--QEIDPSSVCPAIGICPQVEEV--------------------------KH-VTIN 471
+++ Q+ P +C +G C +V+E+ KH V
Sbjct: 257 QMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAK 316
Query: 472 SD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
SD C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 317 SD-VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 359
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 47/174 (27%), Positives = 84/174 (48%), Gaps = 7/174 (4%)
Frame = +1
Query: 91 CPVAKKQTNVRVIGEAEPEPGIVPAL----PIERMFVSVPQNKVVCSFCQYFLHYLQVEL 258
C K+ ++ ++PAL PI++ V ++ V C C++ + + +
Sbjct: 271 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPA-KSDVYCEVCEFLVKEVTKLI 329
Query: 259 SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGICP 438
+++ E ++ A + C LP S++ EC+E VD YG ++ ++L++E+ P VC + +C
Sbjct: 330 DNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIPSILLEEVSPELVCSMLHLCS 389
Query: 439 QVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHL 591
HVT D C +C V L+ L+ N T+ I ALE C+ L
Sbjct: 390 GTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFL 443
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 393 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 452
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 453 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 487
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 63 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
Query: 391 QEID-PSSVCPAIGICPQVEE 450
E+ P VC A+ +C +++
Sbjct: 123 GEMSRPGEVCSALNLCESLQK 143
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 28/162 (17%)
Frame = +1
Query: 202 NKVVCSFCQYFLHYLQVEL-SDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
N VC C + +Q + ++S + V C L + CK ++ QY I
Sbjct: 194 NGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSEIAI 253
Query: 379 ALLVQEIDPSSVCPAIGICPQVEEV--------------------------KH-VTINSD 477
+++ + P +C +G C +V+E+ KH V SD
Sbjct: 254 QMMMH-MQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSD 312
Query: 478 *SNCPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 313 -VYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 353
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 79.4 bits (187), Expect = 9e-15
Identities = 39/134 (29%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +1
Query: 199 QNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVI 378
++ V C C++ + + + +++ E ++ A + C LP S++ EC+E VD YG +++
Sbjct: 7 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSIL 66
Query: 379 ALLVQEIDPSSVCPAIGICPQVE---EVKHVTINSD*SNCPLCLFAVEQLEATLKNNRTE 549
++L++E+ P VC + +C HVT D C +C V L+ L+ N T+
Sbjct: 67 SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTK 126
Query: 550 ANIRKALEGLCTHL 591
I ALE C+ L
Sbjct: 127 QEILAALEKGCSFL 140
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 90 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 149
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 150 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 184
Score = 33.5 bits (73), Expect = 0.59
Identities = 13/39 (33%), Positives = 23/39 (58%)
Frame = +1
Query: 487 CPLCLFAVEQLEATLKNNRTEANIRKALEGLCTHLSQKL 603
C +C F V+++ + NN+TE I A + +C+ L + L
Sbjct: 12 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSL 50
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +1
Query: 166 LPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECK 345
LP + V+ P++ C C+ + YL L + + ++ AA+ C LP +C
Sbjct: 109 LPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCD 168
Query: 346 EFVDQYGPAVIALLVQEIDPSSVCPAIGICPQVEE 450
+FV +Y P +I +LV+ +DPS VC IG CP +
Sbjct: 169 QFVAEYEPVLIEILVEVMDPSFVCLKIGACPSAHK 203
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
Frame = +1
Query: 382 LLVQEIDPSSVCPAIGICPQVEE---VKHVTINSD*SNCPLCLFAVEQLEATLKNNRTEA 552
L+ E+ P VC + +C HVT D C +C V L+ L+ N T+
Sbjct: 87 LVYLEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQ 146
Query: 553 NIRKALEGLCTHL 591
I ALE C+ L
Sbjct: 147 EILAALEKGCSFL 159
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 54.8 bits (126), Expect = 2e-07
Identities = 27/76 (35%), Positives = 38/76 (50%)
Frame = +1
Query: 208 VVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALL 387
V C C + L L + E +T A+ C V+PAS+ EC VD Y P+++ L
Sbjct: 292 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 350
Query: 388 VQEIDPSSVCPAIGIC 435
V +I P VC I +C
Sbjct: 351 VAKITPEKVCKFIRLC 366
Score = 52.4 bits (120), Expect = 1e-06
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQ 393
C+ C+ L L + + A C +LP +CK FV QY P +I L
Sbjct: 396 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 455
Query: 394 EIDPSSVCPAIGIC 435
+DP +VC +G C
Sbjct: 456 MMDPVAVCKKVGAC 469
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 54.8 bits (126), Expect = 2e-07
Identities = 27/76 (35%), Positives = 38/76 (50%)
Frame = +1
Query: 208 VVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALL 387
V C C + L L + E +T A+ C V+PAS+ EC VD Y P+++ L
Sbjct: 314 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 372
Query: 388 VQEIDPSSVCPAIGIC 435
V +I P VC I +C
Sbjct: 373 VAKITPEKVCKFIRLC 388
Score = 52.4 bits (120), Expect = 1e-06
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQ 393
C+ C+ L L + + A C +LP +CK FV QY P +I L
Sbjct: 418 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 477
Query: 394 EIDPSSVCPAIGIC 435
+DP +VC +G C
Sbjct: 478 MMDPVAVCKKVGAC 491
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 54.8 bits (126), Expect = 2e-07
Identities = 27/76 (35%), Positives = 38/76 (50%)
Frame = +1
Query: 208 VVCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALL 387
V C C + L L + E +T A+ C V+PAS+ EC VD Y P+++ L
Sbjct: 24 VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-L 82
Query: 388 VQEIDPSSVCPAIGIC 435
V +I P VC I +C
Sbjct: 83 VAKITPEKVCKFIRLC 98
Score = 52.4 bits (120), Expect = 1e-06
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASVNAECKEFVDQYGPAVIALLVQ 393
C+ C+ L L + + A C +LP +CK FV QY P +I L
Sbjct: 128 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 187
Query: 394 EIDPSSVCPAIGIC 435
+DP +VC +G C
Sbjct: 188 MMDPVAVCKKVGAC 201
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 44.8 bits (101), Expect = 2e-04
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 211 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 387
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 64 LCQECEDIVHILNKMAKEAIFQDTMREFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 123
Query: 388 VQEIDPSSVCPAIGIC 435
+ID +S+C +G+C
Sbjct: 124 QNQIDSNSICMHLGLC 139
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 43.2 bits (97), Expect = 7e-04
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Frame = +1
Query: 211 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 387
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 68 LCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 388 VQEIDPSSVCPAIGIC 435
+ID + +C +G+C
Sbjct: 128 QNQIDSNGICMHLGLC 143
Score = 35.9 bits (79), Expect = 0.11
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +1
Query: 337 ECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
+CK+FV+Q+ P ++ L+ + D + C A+G+C
Sbjct: 334 KCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 366
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 43.2 bits (97), Expect = 7e-04
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Frame = +1
Query: 211 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 387
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 68 LCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 388 VQEIDPSSVCPAIGIC 435
+ID + +C +G+C
Sbjct: 128 QNQIDSNGICMHLGLC 143
Score = 35.9 bits (79), Expect = 0.11
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +1
Query: 337 ECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
+CK+FV+Q+ P ++ L+ + D + C A+G+C
Sbjct: 334 KCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 366
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 41.1 bits (92), Expect = 0.003
Identities = 18/76 (23%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Frame = +1
Query: 211 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 387
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 68 LCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 388 VQEIDPSSVCPAIGIC 435
+ D + +C +G+C
Sbjct: 128 QNQTDSNGICMHLGLC 143
Score = 35.9 bits (79), Expect = 0.11
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +1
Query: 337 ECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
+CK+FV+Q+ P ++ L+ + D + C A+G+C
Sbjct: 334 KCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 366
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 41.1 bits (92), Expect = 0.003
Identities = 18/76 (23%), Positives = 35/76 (46%), Gaps = 1/76 (1%)
Frame = +1
Query: 211 VCSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPASV-NAECKEFVDQYGPAVIALL 387
+C C+ +H L ++ + + + C VLP + +C + +D Y P VI
Sbjct: 68 LCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127
Query: 388 VQEIDPSSVCPAIGIC 435
+ D + +C +G+C
Sbjct: 128 QNQTDSNGICMHLGLC 143
Score = 35.9 bits (79), Expect = 0.11
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +1
Query: 337 ECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
+CK+FV+Q+ P ++ L+ + D + C A+G+C
Sbjct: 334 KCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 366
>M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary
surfactant apoprotein 18 (SP 18) mRNA, 3' end. ).
Length = 243
Score = 35.9 bits (79), Expect = 0.11
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +1
Query: 337 ECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
+CK+FV+Q+ P ++ L+ + D + C A+G+C
Sbjct: 196 KCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 228
>M16764-1|AAA88099.1| 286|Homo sapiens pulmonary
surfactant-associated proteolipid protein protein.
Length = 286
Score = 35.9 bits (79), Expect = 0.11
Identities = 12/33 (36%), Positives = 23/33 (69%)
Frame = +1
Query: 337 ECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
+CK+FV+Q+ P ++ L+ + D + C A+G+C
Sbjct: 239 KCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVC 271
Score = 34.7 bits (76), Expect = 0.26
Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Frame = +1
Query: 307 CGVLPASV-NAECKEFVDQYGPAVIALLVQEIDPSSVCPAIGIC 435
C VLP + +C + +D Y P VI + D + +C +G+C
Sbjct: 5 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLC 48
>X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate
activator protein.
Length = 67
Score = 35.5 bits (78), Expect = 0.15
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Frame = +1
Query: 214 CSFCQYFLHYLQVELSDSRVEAKVTAAVNAACGVLPA-SVNAECKEFVDQYGPAVIALLV 390
C C+ + L D+ E ++ + C LP +++A CKE VD Y P ++ ++
Sbjct: 5 CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 64
Query: 391 QEI 399
E+
Sbjct: 65 GEM 67
>BC039729-1|AAH39729.1| 516|Homo sapiens RIOK3 protein protein.
Length = 516
Score = 31.5 bits (68), Expect = 2.4
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +1
Query: 124 VIGEAEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNA 303
++G A PEPG A + ++PQN + CS L EL EA V V
Sbjct: 3 LVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKEL-QLEEEAAVFPEVAV 61
Query: 304 ACG 312
A G
Sbjct: 62 AEG 64
>BC028360-1|AAH28360.1| 424|Homo sapiens RIO kinase 3 (yeast)
protein.
Length = 424
Score = 31.5 bits (68), Expect = 2.4
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +1
Query: 124 VIGEAEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNA 303
++G A PEPG A + ++PQN + CS L EL EA V V
Sbjct: 3 LVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKEL-QLEEEAAVFPEVAV 61
Query: 304 ACG 312
A G
Sbjct: 62 AEG 64
>AF013591-1|AAC26080.1| 519|Homo sapiens homolog of the Aspergillus
nidulans sudD gene product protein.
Length = 519
Score = 31.5 bits (68), Expect = 2.4
Identities = 21/63 (33%), Positives = 27/63 (42%)
Frame = +1
Query: 124 VIGEAEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHYLQVELSDSRVEAKVTAAVNA 303
++G A PEPG A + ++PQN + CS L EL EA V V
Sbjct: 3 LVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKEL-QLEEEAAVFPEVAV 61
Query: 304 ACG 312
A G
Sbjct: 62 AEG 64
>J05500-2|AAA60578.1| 2106|Homo sapiens SPTB protein.
Length = 2106
Score = 29.5 bits (63), Expect = 9.6
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +1
Query: 136 AEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHY 243
AE + GI+P L E +F P K + ++ F HY
Sbjct: 241 AERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHY 276
>J05500-1|AAA60579.1| 2137|Homo sapiens SPTB protein.
Length = 2137
Score = 29.5 bits (63), Expect = 9.6
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +1
Query: 136 AEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHY 243
AE + GI+P L E +F P K + ++ F HY
Sbjct: 241 AERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHY 276
>AK127156-1|BAC86859.1| 204|Homo sapiens protein ( Homo sapiens
cDNA FLJ45218 fis, clone BRCAN2019653. ).
Length = 204
Score = 29.5 bits (63), Expect = 9.6
Identities = 11/31 (35%), Positives = 16/31 (51%)
Frame = -3
Query: 170 GSAGTIPGSGSASPITRTFVCFLATGHTCYL 78
G G G +A+P R F C L G +C++
Sbjct: 146 GQPGPFEGGTAATPTPRFFACLLTAGVSCFV 176
>AB209415-1|BAD92652.1| 2332|Homo sapiens spectrin, beta,
erythrocytic (includes spherocytosis, clinical type I)
variant protein.
Length = 2332
Score = 29.5 bits (63), Expect = 9.6
Identities = 13/36 (36%), Positives = 19/36 (52%)
Frame = +1
Query: 136 AEPEPGIVPALPIERMFVSVPQNKVVCSFCQYFLHY 243
AE + GI+P L E +F P K + ++ F HY
Sbjct: 245 AERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHY 280
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,993,085
Number of Sequences: 237096
Number of extensions: 1581251
Number of successful extensions: 4339
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 4100
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4320
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6410414940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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