Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0011_M13
(590 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 80 5e-15
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 80 5e-15
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 80 5e-15
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 80 5e-15
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 80 5e-15
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 80 5e-15
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 80 5e-15
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 80 5e-15
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 80 5e-15
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 80 5e-15
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 80 5e-15
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 80 5e-15
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 80 5e-15
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 80 5e-15
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 80 5e-15
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 80 5e-15
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 78 2e-14
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 54 4e-07
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 54 4e-07
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 54 4e-07
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 52 2e-06
M24461-1|AAB59541.1| 381|Homo sapiens pulmonary surfactant-asso... 44 4e-04
AF400074-1|AAK77913.1| 381|Homo sapiens surfactant, pulmonary-a... 44 4e-04
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 43 7e-04
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 43 7e-04
DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant pu... 42 0.002
X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate activ... 40 0.009
M16764-1|AAA88099.1| 286|Homo sapiens pulmonary surfactant-asso... 33 0.76
M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary... 32 1.7
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 32 1.7
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 32 1.7
X05044-2|CAA28715.1| 129|Homo sapiens protein ( Human mRNA (AH2... 31 3.0
M85276-1|AAA59935.1| 145|Homo sapiens NKG5 protein protein. 31 3.0
BC107598-1|AAI07599.1| 92|Homo sapiens CNPY1 protein protein. 29 9.3
BC105734-1|AAI05735.1| 92|Homo sapiens CNPY1 protein protein. 29 9.3
BC105733-1|AAI05734.1| 92|Homo sapiens CNPY1 protein protein. 29 9.3
BC105732-1|AAI05733.1| 92|Homo sapiens CNPY1 protein protein. 29 9.3
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 42 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 101
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 102 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 161
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 162 ILVEVMDPSFVCLKIGAC 179
Score = 59.3 bits (137), Expect = 1e-08
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +1
Query: 217 CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIE 393
C VCE +V V K++ N+ + +I+ +K C LP S C +++ YG S++ L+E
Sbjct: 12 CEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLE 71
Query: 394 EFGINGVCQKIGLCSTT 444
E VC + LCS T
Sbjct: 72 EVSPELVCSMLHLCSGT 88
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 347 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 406
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 407 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 466
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 467 ILVEVMDPSFVCLKIGAC 484
Score = 62.5 bits (145), Expect = 1e-09
Identities = 36/124 (29%), Positives = 64/124 (51%), Gaps = 6/124 (4%)
Frame = +1
Query: 91 YADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEI-----LDCAVCETVVMAVKK 255
+ D V + Q L P++V ++ + P++ + +K E+ + C VCE +V V K
Sbjct: 272 FCDEVKEMPMQTLVPAKVASKNVI--PALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTK 329
Query: 256 VLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGL 432
++ N+ + +I+ +K C LP S C +++ YG S++ L+EE VC + L
Sbjct: 330 LIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHL 389
Query: 433 CSTT 444
CS T
Sbjct: 390 CSGT 393
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 62.5 bits (145), Expect = 1e-09
Identities = 36/124 (29%), Positives = 64/124 (51%), Gaps = 6/124 (4%)
Frame = +1
Query: 91 YADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEI-----LDCAVCETVVMAVKK 255
+ D V + Q L P++V ++ + P++ + +K E+ + C VCE +V V K
Sbjct: 270 FCDEVKEMPMQTLVPAKVASKNVI--PALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTK 327
Query: 256 VLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGL 432
++ N+ + +I+ +K C LP S C +++ YG S++ L+EE VC + L
Sbjct: 328 LIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHL 387
Query: 433 CSTT 444
CS T
Sbjct: 388 CSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 348 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 407
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 408 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 467
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 468 ILVEVMDPSFVCLKIGAC 485
Score = 62.5 bits (145), Expect = 1e-09
Identities = 36/124 (29%), Positives = 64/124 (51%), Gaps = 6/124 (4%)
Frame = +1
Query: 91 YADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEI-----LDCAVCETVVMAVKK 255
+ D V + Q L P++V ++ + P++ + +K E+ + C VCE +V V K
Sbjct: 273 FCDEVKEMPMQTLVPAKVASKNVI--PALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTK 330
Query: 256 VLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGL 432
++ N+ + +I+ +K C LP S C +++ YG S++ L+EE VC + L
Sbjct: 331 LIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHL 390
Query: 433 CSTT 444
CS T
Sbjct: 391 CSGT 394
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 348 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 407
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 408 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 467
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 468 ILVEVMDPSFVCLKIGAC 485
Score = 65.7 bits (153), Expect = 1e-10
Identities = 41/171 (23%), Positives = 78/171 (45%), Gaps = 29/171 (16%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLA--QELEPSEVCTELKLCK-------- 168
E++ C R+ + C ++ +Y+++ I ++ Q+ +P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQ 283
Query: 169 -------------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVH 294
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 284 TLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILD 343
Query: 295 VVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 344 AFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 394
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 65.7 bits (153), Expect = 1e-10
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 80.2 bits (189), Expect = 5e-15
Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y ++S+L +E+ P VC+ L LC + +V +
Sbjct: 351 MCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 410
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 411 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 470
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 471 ILVEVMDPSFVCLKIGAC 488
Score = 65.7 bits (153), Expect = 1e-10
Identities = 41/171 (23%), Positives = 78/171 (45%), Gaps = 29/171 (16%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLA--QELEPSEVCTELKLCK-------- 168
E++ C R+ + C ++ +Y+++ I ++ Q+ +P E+C + C
Sbjct: 227 EHVKEECDRLGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQ 286
Query: 169 -------------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVH 294
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 287 TLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILD 346
Query: 295 VVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S++ L+EE VC + LCS T
Sbjct: 347 AFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGT 397
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 37 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 93
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 94 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 153
Query: 472 EKR 480
+K+
Sbjct: 154 QKQ 156
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 78.2 bits (184), Expect = 2e-14
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 4/138 (2%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
+C ++PKS+ EC + V+ Y + S+L +E+ P VC+ L LC + +V +
Sbjct: 345 MCSKLPKSLSEECQEVVDTYGSSIPSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPK 404
Query: 214 D---CAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH 384
D C VC+ +V + + L ++ +I+ +EK C LP Y +C + Y +I
Sbjct: 405 DGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIE 464
Query: 385 -LIEEFGINGVCQKIGLC 435
L+E + VC KIG C
Sbjct: 465 ILVEVMDPSFVCLKIGAC 482
Score = 63.7 bits (148), Expect = 5e-10
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 27/169 (15%)
Frame = +1
Query: 19 ENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCK---------- 168
E++ C R+ + C ++ +Y+++ I ++ ++P E+C + C
Sbjct: 224 EHVKEECDRLGPGMADICKNYISQYSEIAIQMM-MHMQPKEICALVGFCDEVKEMPMQTL 282
Query: 169 -----------PSIPNFDSVKAGEI-----LDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
P++ + +K E+ + C VCE +V V K++ N+ + +I+
Sbjct: 283 VPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAF 342
Query: 301 EKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLCSTT 444
+K C LP S C +++ YG S+ L+EE VC + LCS T
Sbjct: 343 DKMCSKLPKSLSEECQEVVDTYGSSIPSILLEEVSPELVCSMLHLCSGT 391
Score = 53.6 bits (123), Expect = 5e-07
Identities = 33/123 (26%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 EKACGLLP-AKYSARCHTMMEVYGDSVIHLIE-EFGING-VCQKIGLCSTTESAYVRMYR 471
EK C LP SA C +++ Y ++ +I+ E G VC + LC + + +
Sbjct: 91 EKTCDWLPKPNMSASCKEIVDSYLPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNH 150
Query: 472 EKR 480
+K+
Sbjct: 151 QKQ 153
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 54.0 bits (124), Expect = 4e-07
Identities = 39/158 (24%), Positives = 70/158 (44%), Gaps = 16/158 (10%)
Frame = +1
Query: 10 MKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLC-------- 165
M + + VC MP S+ EC V+ Y+ ++ L+A ++ P +VC ++LC
Sbjct: 316 MITHALERVCSVMPASITKECIILVDTYSPSLVQLVA-KITPEKVCKFIRLCGNRRRARA 374
Query: 166 -------KPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLP 324
PS P +D+ G C C+ ++ L + + DI+ + C +LP
Sbjct: 375 VHDAYAIVPS-PEWDAENQGSF--CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILP 431
Query: 325 AKYSARCHTMMEVYGDSVIHLIEE-FGINGVCQKIGLC 435
Y +C + Y +I +++ VC+K+G C
Sbjct: 432 LPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 469
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/100 (28%), Positives = 50/100 (50%)
Frame = +1
Query: 154 LKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKY 333
L+L P + +KAG + C VC VV + L +++ + I H +E+ C ++PA
Sbjct: 275 LELGLPRKQSEMQMKAG--VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASI 332
Query: 334 SARCHTMMEVYGDSVIHLIEEFGINGVCQKIGLCSTTESA 453
+ C +++ Y S++ L+ + VC+ I LC A
Sbjct: 333 TKECIILVDTYSPSLVQLVAKITPEKVCKFIRLCGNRRRA 372
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 4/109 (3%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q+L+ + C + C+ ++ N + K+ L C VC+ + A L+ DA + DI+ +V
Sbjct: 35 QDLQTAARCGAVGYCQGAVWNKPTAKS---LPCDVCQDIAAAAGNGLNPDATESDILALV 91
Query: 301 EKACGLLPA-KYSARCHTMMEVYGDSVIHLIE---EFGINGVCQKIGLC 435
K C LP+ + SA C M++ + +++ ++ + VC + LC
Sbjct: 92 MKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALSLC 140
Score = 34.3 bits (75), Expect = 0.33
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Frame = +1
Query: 37 CKRMPKSVKSE-CDQFVEKYADLVISLL--AQELEPSEVCTELKLCKP 171
C+ +P S C V+ ++ ++S+L A + P++VCT L LC+P
Sbjct: 95 CEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALSLCEP 142
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 54.0 bits (124), Expect = 4e-07
Identities = 39/158 (24%), Positives = 70/158 (44%), Gaps = 16/158 (10%)
Frame = +1
Query: 10 MKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLC-------- 165
M + + VC MP S+ EC V+ Y+ ++ L+A ++ P +VC ++LC
Sbjct: 338 MITHALERVCSVMPASITKECIILVDTYSPSLVQLVA-KITPEKVCKFIRLCGNRRRARA 396
Query: 166 -------KPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLP 324
PS P +D+ G C C+ ++ L + + DI+ + C +LP
Sbjct: 397 VHDAYAIVPS-PEWDAENQGSF--CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILP 453
Query: 325 AKYSARCHTMMEVYGDSVIHLIEE-FGINGVCQKIGLC 435
Y +C + Y +I +++ VC+K+G C
Sbjct: 454 LPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 491
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/100 (28%), Positives = 50/100 (50%)
Frame = +1
Query: 154 LKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKY 333
L+L P + +KAG + C VC VV + L +++ + I H +E+ C ++PA
Sbjct: 297 LELGLPRKQSEMQMKAG--VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASI 354
Query: 334 SARCHTMMEVYGDSVIHLIEEFGINGVCQKIGLCSTTESA 453
+ C +++ Y S++ L+ + VC+ I LC A
Sbjct: 355 TKECIILVDTYSPSLVQLVAKITPEKVCKFIRLCGNRRRA 394
Score = 48.8 bits (111), Expect = 1e-05
Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 4/109 (3%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q+L+ + C + C+ ++ N + K+ L C VC+ + A L+ DA + DI+ +V
Sbjct: 57 QDLQTAARCGAVGYCQGAVWNKPTAKS---LPCDVCQDIAAAAGNGLNPDATESDILALV 113
Query: 301 EKACGLLPA-KYSARCHTMMEVYGDSVIHLIE---EFGINGVCQKIGLC 435
K C LP+ + SA C M++ + +++ ++ + VC + LC
Sbjct: 114 MKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALSLC 162
Score = 34.3 bits (75), Expect = 0.33
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Frame = +1
Query: 37 CKRMPKSVKSE-CDQFVEKYADLVISLL--AQELEPSEVCTELKLCKP 171
C+ +P S C V+ ++ ++S+L A + P++VCT L LC+P
Sbjct: 117 CEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALSLCEP 164
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 54.0 bits (124), Expect = 4e-07
Identities = 39/158 (24%), Positives = 70/158 (44%), Gaps = 16/158 (10%)
Frame = +1
Query: 10 MKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLC-------- 165
M + + VC MP S+ EC V+ Y+ ++ L+A ++ P +VC ++LC
Sbjct: 48 MITHALERVCSVMPASITKECIILVDTYSPSLVQLVA-KITPEKVCKFIRLCGNRRRARA 106
Query: 166 -------KPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLP 324
PS P +D+ G C C+ ++ L + + DI+ + C +LP
Sbjct: 107 VHDAYAIVPS-PEWDAENQGSF--CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILP 163
Query: 325 AKYSARCHTMMEVYGDSVIHLIEE-FGINGVCQKIGLC 435
Y +C + Y +I +++ VC+K+G C
Sbjct: 164 LPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGAC 201
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/100 (28%), Positives = 50/100 (50%)
Frame = +1
Query: 154 LKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKY 333
L+L P + +KAG + C VC VV + L +++ + I H +E+ C ++PA
Sbjct: 7 LELGLPRKQSEMQMKAG--VTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASI 64
Query: 334 SARCHTMMEVYGDSVIHLIEEFGINGVCQKIGLCSTTESA 453
+ C +++ Y S++ L+ + VC+ I LC A
Sbjct: 65 TKECIILVDTYSPSLVQLVAKITPEKVCKFIRLCGNRRRA 104
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 51.6 bits (118), Expect = 2e-06
Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 4/112 (3%)
Frame = +1
Query: 112 LLAQELEPSEVCTELKLCKPSIPNFDSVKAGEILD---CAVCETVVMAVKKVLSNDAVDH 282
L+ E+ P VC+ L LC + +V + D C VC+ +V + + L ++
Sbjct: 87 LVYLEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQ 146
Query: 283 DIVHVVEKACGLLPAKYSARCHTMMEVYGDSVIH-LIEEFGINGVCQKIGLC 435
+I+ +EK C LP Y +C + Y +I L+E + VC KIG C
Sbjct: 147 EILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 198
Score = 42.3 bits (95), Expect = 0.001
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = +1
Query: 37 CKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLC 165
C +P + +CDQFV +Y ++I +L + ++PS VC ++ C
Sbjct: 156 CSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCLKIGAC 198
Score = 31.9 bits (69), Expect = 1.7
Identities = 17/61 (27%), Positives = 34/61 (55%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVHVV 300
Q ++ + C +K C ++ N +VK+ L C +C+ VV A +L ++A + +I+ +
Sbjct: 34 QNVKTASDCGAVKHCLQTVWNKPTVKS---LPCDICKDVVTAAGDMLKDNATEEEILVYL 90
Query: 301 E 303
E
Sbjct: 91 E 91
>M24461-1|AAB59541.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 44.0 bits (99), Expect = 4e-04
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVH-V 297
Q LE + C L C + + V A ++ C CE +V + K ++ +A+ D +
Sbjct: 41 QSLEQALQCRALGHCLQEV--WGHVGADDL--CQECEDIVHILNK-MAKEAIFQDTMRKF 95
Query: 298 VEKACGLLPAK-YSARCHTMMEVYGDSVIHLIE-EFGINGVCQKIGLCSTTE 447
+E+ C +LP K +C+ +++ Y VI + + NG+C +GLC + +
Sbjct: 96 LEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQIDSNGICMHLGLCKSRQ 147
Score = 34.3 bits (75), Expect = 0.33
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Frame = +1
Query: 37 CKRMP-KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIP 180
C +P K + +C+Q ++ Y LVI +++ + +C L LCK P
Sbjct: 100 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQIDSNGICMHLGLCKSRQP 148
Score = 31.5 bits (68), Expect = 2.3
Identities = 31/144 (21%), Positives = 58/144 (40%), Gaps = 5/144 (3%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
VC+ +P C E+Y+ +++ L + P VC + C GE L
Sbjct: 234 VCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWL 293
Query: 214 ----DCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVI 381
+C +C M+V N + + I + +AC + +C +E + ++
Sbjct: 294 PRDSECHLC----MSVTTQAGNSS-EQAIPQAMLQAC-VGSWLDREKCKQFVEQHTPQLL 347
Query: 382 HLIEE-FGINGVCQKIGLCSTTES 450
L+ + + CQ +G+C T S
Sbjct: 348 TLVPRGWDAHTTCQALGVCGTMSS 371
>AF400074-1|AAK77913.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 44.0 bits (99), Expect = 4e-04
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVH-V 297
Q LE + C L C + + V A ++ C CE +V + K ++ +A+ D +
Sbjct: 41 QSLEQALQCRALGHCLQEV--WGHVGADDL--CQECEDIVHILNK-MAKEAIFQDTMRKF 95
Query: 298 VEKACGLLPAK-YSARCHTMMEVYGDSVIHLIE-EFGINGVCQKIGLCSTTE 447
+E+ C +LP K +C+ +++ Y VI + + NG+C +GLC + +
Sbjct: 96 LEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQIDSNGICMHLGLCKSRQ 147
Score = 34.3 bits (75), Expect = 0.33
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Frame = +1
Query: 37 CKRMP-KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIP 180
C +P K + +C+Q ++ Y LVI +++ + +C L LCK P
Sbjct: 100 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQIDSNGICMHLGLCKSRQP 148
Score = 31.9 bits (69), Expect = 1.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Frame = +1
Query: 4 RGMKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPN 183
+G + + VC+ +P C E+Y+ +++ L + P VC + C
Sbjct: 224 KGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSA 283
Query: 184 FDSVKAGEIL----DCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHT 351
GE L +C +C M+V N + + I + +AC + +C
Sbjct: 284 GPRSPTGEWLPRDSECHLC----MSVTTQAGNSS-EQAIPQAMLQAC-VGSWLDREKCKQ 337
Query: 352 MMEVYGDSVIHLIEE-FGINGVCQKIGLCSTTES 450
+E + ++ L+ + + CQ +G+C T S
Sbjct: 338 FVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSS 371
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVH-V 297
Q LE + C L C + + V A ++ C CE +V + K ++ +A+ D +
Sbjct: 41 QSLEQALQCRALGHCLQEV--WGHVGADDL--CQECEDIVHILNK-MAKEAIFQDTMRKF 95
Query: 298 VEKACGLLPAK-YSARCHTMMEVYGDSVIHLIE-EFGINGVCQKIGLCSTTE 447
+E+ C +LP K +C+ +++ Y VI + + NG+C +GLC + +
Sbjct: 96 LEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQ 147
Score = 33.1 bits (72), Expect = 0.76
Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Frame = +1
Query: 37 CKRMP-KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIP 180
C +P K + +C+Q ++ Y LVI + + + +C L LCK P
Sbjct: 100 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQP 148
Score = 31.9 bits (69), Expect = 1.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Frame = +1
Query: 4 RGMKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPN 183
+G + + VC+ +P C E+Y+ +++ L + P VC + C
Sbjct: 224 KGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSA 283
Query: 184 FDSVKAGEIL----DCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHT 351
GE L +C +C M+V N + + I + +AC + +C
Sbjct: 284 GPRSPTGEWLPRDSECHLC----MSVTTQAGNSS-EQAIPQAMLQAC-VGSWLDREKCKQ 337
Query: 352 MMEVYGDSVIHLIEE-FGINGVCQKIGLCSTTES 450
+E + ++ L+ + + CQ +G+C T S
Sbjct: 338 FVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSS 371
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVH-V 297
Q LE + C L C + + V A ++ C CE +V + K ++ +A+ D +
Sbjct: 41 QSLEQALQCRALGHCLQEV--WGHVGADDL--CQECEDIVHILNK-MAKEAIFQDTMRKF 95
Query: 298 VEKACGLLPAK-YSARCHTMMEVYGDSVIHLIE-EFGINGVCQKIGLCSTTE 447
+E+ C +LP K +C+ +++ Y VI + + NG+C +GLC + +
Sbjct: 96 LEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQ 147
Score = 33.1 bits (72), Expect = 0.76
Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Frame = +1
Query: 37 CKRMP-KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIP 180
C +P K + +C+Q ++ Y LVI + + + +C L LCK P
Sbjct: 100 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQP 148
Score = 31.9 bits (69), Expect = 1.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Frame = +1
Query: 4 RGMKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPN 183
+G + + VC+ +P C E+Y+ +++ L + P VC + C
Sbjct: 224 KGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSA 283
Query: 184 FDSVKAGEIL----DCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHT 351
GE L +C +C M+V N + + I + +AC + +C
Sbjct: 284 GPRSPTGEWLPRDSECHLC----MSVTTQAGNSS-EQAIPQAMLQAC-VGSWLDREKCKQ 337
Query: 352 MMEVYGDSVIHLIEE-FGINGVCQKIGLCSTTES 450
+E + ++ L+ + + CQ +G+C T S
Sbjct: 338 FVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSS 371
>DQ317589-1|ABC59511.1| 147|Homo sapiens truncated surfactant
pulmonary-associated protein B protein.
Length = 147
Score = 41.5 bits (93), Expect = 0.002
Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Frame = +1
Query: 121 QELEPSEVCTELKLCKPSIPNFDSVKAGEILDCAVCETVVMAVKKVLSNDAVDHDIVH-V 297
Q LE + C L C + + V A ++ C CE +V + K ++ +A+ D +
Sbjct: 37 QSLEQALQCRALGHCLQEV--WGHVGADDL--CQECEDIVHILNK-MAKEAIFQDTMREF 91
Query: 298 VEKACGLLPAK-YSARCHTMMEVYGDSVIHLIE-EFGINGVCQKIGLCSTTE 447
+E+ C +LP K +C+ +++ Y VI + + N +C +GLC + +
Sbjct: 92 LEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQIDSNSICMHLGLCKSRQ 143
Score = 35.1 bits (77), Expect = 0.19
Identities = 15/49 (30%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Frame = +1
Query: 37 CKRMP-KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIP 180
C +P K + +C+Q ++ Y LVI +++ + +C L LCK P
Sbjct: 96 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQIDSNSICMHLGLCKSRQP 144
>X57107-1|CAA40391.1| 67|Homo sapiens cerebroside sulfate
activator protein.
Length = 67
Score = 39.5 bits (88), Expect = 0.009
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +1
Query: 211 LDCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLP-AKYSARCHTMMEVYGDSVIHL 387
L C +C+ VV A +L ++A + +I+ +EK C LP SA C +++ Y ++ +
Sbjct: 3 LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 62
Query: 388 IE 393
I+
Sbjct: 63 IK 64
>M16764-1|AAA88099.1| 286|Homo sapiens pulmonary
surfactant-associated proteolipid protein protein.
Length = 286
Score = 33.1 bits (72), Expect = 0.76
Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Frame = +1
Query: 37 CKRMP-KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIP 180
C +P K + +C+Q ++ Y LVI + + + +C L LCK P
Sbjct: 5 CNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQP 53
Score = 32.7 bits (71), Expect = 1.00
Identities = 31/144 (21%), Positives = 59/144 (40%), Gaps = 5/144 (3%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEIL 213
VC+ +P C E+Y+ +++ L + P VC + C GE L
Sbjct: 139 VCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWL 198
Query: 214 ----DCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHTMMEVYGDSVI 381
+C +C M+V N + + I+ + +AC + +C +E + ++
Sbjct: 199 PRDSECHLC----MSVTTQAGNSS-EQAILQAMLQAC-VGSWLDREKCKQFVEQHTPQLL 252
Query: 382 HLIEE-FGINGVCQKIGLCSTTES 450
L+ + + CQ +G+C T S
Sbjct: 253 TLVPRGWDAHTTCQALGVCGTMSS 276
Score = 30.3 bits (65), Expect = 5.3
Identities = 14/50 (28%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Frame = +1
Query: 304 KACGLLPAKY-SARCHTMMEVYGDSVIHLIE-EFGINGVCQKIGLCSTTE 447
+ C +LP K +C+ +++ Y VI + + NG+C +GLC + +
Sbjct: 3 RECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQ 52
>M19097-1|AAA36628.1| 243|Homo sapiens protein ( Human pulmonary
surfactant apoprotein 18 (SP 18) mRNA, 3' end. ).
Length = 243
Score = 31.9 bits (69), Expect = 1.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Frame = +1
Query: 4 RGMKSENIHGVCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPN 183
+G + + VC+ +P C E+Y+ +++ L + P VC + C
Sbjct: 86 KGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSA 145
Query: 184 FDSVKAGEIL----DCAVCETVVMAVKKVLSNDAVDHDIVHVVEKACGLLPAKYSARCHT 351
GE L +C +C M+V N + + I + +AC + +C
Sbjct: 146 GPRSPTGEWLPRDSECHLC----MSVTTQAGNSS-EQAIPQAMLQAC-VGSWLDREKCKQ 199
Query: 352 MMEVYGDSVIHLIEE-FGINGVCQKIGLCSTTES 450
+E + ++ L+ + + CQ +G+C T S
Sbjct: 200 FVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSS 233
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 31.9 bits (69), Expect = 1.7
Identities = 19/55 (34%), Positives = 25/55 (45%)
Frame = +1
Query: 52 KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEILD 216
+S + DQ EK DL L +LE + E+K K + NFD EI D
Sbjct: 2372 ESTIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEIED 2426
>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
Length = 1540
Score = 31.9 bits (69), Expect = 1.7
Identities = 19/55 (34%), Positives = 25/55 (45%)
Frame = +1
Query: 52 KSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPSIPNFDSVKAGEILD 216
+S + DQ EK DL L +LE + E+K K + NFD EI D
Sbjct: 1433 ESTIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEIED 1487
>X05044-2|CAA28715.1| 129|Homo sapiens protein ( Human mRNA
(AH2-519) for gene 519 from functional T-cell line. ).
Length = 129
Score = 31.1 bits (67), Expect = 3.0
Identities = 14/47 (29%), Positives = 22/47 (46%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPS 174
VC+ + C F+ +Y VI L ++C +L+LC PS
Sbjct: 79 VCRTGRSRWRDVCRNFMRRYQSRVIQGLVAGETAQQICEDLRLCIPS 125
>M85276-1|AAA59935.1| 145|Homo sapiens NKG5 protein protein.
Length = 145
Score = 31.1 bits (67), Expect = 3.0
Identities = 14/47 (29%), Positives = 22/47 (46%)
Frame = +1
Query: 34 VCKRMPKSVKSECDQFVEKYADLVISLLAQELEPSEVCTELKLCKPS 174
VC+ + C F+ +Y VI L ++C +L+LC PS
Sbjct: 95 VCRTGRSRWRDVCRNFMRRYQSRVIQGLVAGETAQQICEDLRLCIPS 141
>BC107598-1|AAI07599.1| 92|Homo sapiens CNPY1 protein protein.
Length = 92
Score = 29.5 bits (63), Expect = 9.3
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +1
Query: 52 KSVKSECDQFVEKYADLVISLLAQELE--PSEVCTELK-LCKPS 174
+ +K C+ +E+Y D + SL+AQE ++C+E LC+ S
Sbjct: 43 RPLKFACETIIEEYEDEISSLIAQETHYLADKLCSEKSDLCETS 86
>BC105734-1|AAI05735.1| 92|Homo sapiens CNPY1 protein protein.
Length = 92
Score = 29.5 bits (63), Expect = 9.3
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +1
Query: 52 KSVKSECDQFVEKYADLVISLLAQELE--PSEVCTELK-LCKPS 174
+ +K C+ +E+Y D + SL+AQE ++C+E LC+ S
Sbjct: 43 RPLKFACETIIEEYEDEISSLIAQETHYLADKLCSEKSDLCETS 86
>BC105733-1|AAI05734.1| 92|Homo sapiens CNPY1 protein protein.
Length = 92
Score = 29.5 bits (63), Expect = 9.3
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +1
Query: 52 KSVKSECDQFVEKYADLVISLLAQELE--PSEVCTELK-LCKPS 174
+ +K C+ +E+Y D + SL+AQE ++C+E LC+ S
Sbjct: 43 RPLKFACETIIEEYEDEISSLIAQETHYLADKLCSEKSDLCETS 86
>BC105732-1|AAI05733.1| 92|Homo sapiens CNPY1 protein protein.
Length = 92
Score = 29.5 bits (63), Expect = 9.3
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Frame = +1
Query: 52 KSVKSECDQFVEKYADLVISLLAQELE--PSEVCTELK-LCKPS 174
+ +K C+ +E+Y D + SL+AQE ++C+E LC+ S
Sbjct: 43 RPLKFACETIIEEYEDEISSLIAQETHYLADKLCSEKSDLCETS 86
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,832,157
Number of Sequences: 237096
Number of extensions: 1393757
Number of successful extensions: 10707
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 10500
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10643
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6211568660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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