Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0010_J15
(412 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7Q0A0 Cluster: ENSANGP00000020090; n=3; Endopterygota|... 173 9e-43
UniRef50_Q17DN9 Cluster: Enhancer of split protein, putative; n=... 170 1e-41
UniRef50_Q01070 Cluster: Enhancer of split mgamma protein (E(spl... 122 2e-27
UniRef50_Q01069 Cluster: Enhancer of split mbeta protein (E(spl)... 122 3e-27
UniRef50_Q01071 Cluster: Enhancer of split mdelta protein (E(spl... 106 2e-22
UniRef50_Q01068 Cluster: Enhancer of split m3 protein (E(spl)m3)... 102 2e-21
UniRef50_Q9N6W7 Cluster: HLHmdelta protein; n=1; Drosophila hyde... 89 3e-17
UniRef50_UPI00003BFC0E Cluster: PREDICTED: similar to deadpan CG... 81 1e-14
UniRef50_Q9NFW8 Cluster: DNA-binding-protein hairy; n=2; Enteleg... 81 1e-14
UniRef50_Q26263 Cluster: Protein deadpan; n=3; Protostomia|Rep: ... 80 2e-14
UniRef50_P13098 Cluster: Enhancer of split m8 protein (E(spl)m8)... 79 3e-14
UniRef50_Q29G34 Cluster: GA19235-PA; n=1; Drosophila pseudoobscu... 78 8e-14
UniRef50_UPI00015B599D Cluster: PREDICTED: similar to hairy prot... 77 1e-13
UniRef50_Q14469 Cluster: Transcription factor HES-1; n=52; Eutel... 77 1e-13
UniRef50_Q90468 Cluster: HER-6 protein; n=4; Clupeocephala|Rep: ... 76 3e-13
UniRef50_UPI00003C06C0 Cluster: PREDICTED: similar to Protein ha... 75 6e-13
UniRef50_Q9VWX7 Cluster: CG5927-PA; n=1; Drosophila melanogaster... 75 6e-13
UniRef50_Q16NK4 Cluster: Hairy protein; n=4; Diptera|Rep: Hairy ... 74 1e-12
UniRef50_Q208Q9 Cluster: AmphiHairyA; n=6; Branchiostoma florida... 74 1e-12
UniRef50_A2TIR6 Cluster: Splhairy; n=1; Panulirus argus|Rep: Spl... 74 1e-12
UniRef50_Q4H3N9 Cluster: Transcription factor protein; n=3; Eume... 73 2e-12
UniRef50_Q6V6Z0 Cluster: Hairy G protein; n=1; Branchiostoma flo... 73 3e-12
UniRef50_P29303 Cluster: Protein hairy; n=2; Muscomorpha|Rep: Pr... 73 3e-12
UniRef50_Q8T306 Cluster: Helix-loop-helix transcription factor; ... 72 4e-12
UniRef50_UPI0001554A1E Cluster: PREDICTED: hypothetical protein;... 71 7e-12
UniRef50_Q17DP5 Cluster: Hairy protein; n=2; Culicidae|Rep: Hair... 71 7e-12
UniRef50_UPI0000D57461 Cluster: PREDICTED: similar to CG8704-PA;... 71 1e-11
UniRef50_P14003 Cluster: Protein hairy; n=3; Sophophora|Rep: Pro... 71 1e-11
UniRef50_Q6V6Z2 Cluster: Hairy E protein; n=3; Branchiostoma flo... 70 2e-11
UniRef50_A7RU73 Cluster: Predicted protein; n=1; Nematostella ve... 69 4e-11
UniRef50_Q56KF1 Cluster: Enhancer of split m5 protein; n=2; Dros... 68 9e-11
UniRef50_Q9Y543 Cluster: Transcription factor HES-2; n=14; Theri... 67 1e-10
UniRef50_Q568C3 Cluster: Her3 protein; n=3; Danio rerio|Rep: Her... 66 2e-10
UniRef50_A7RYX4 Cluster: Predicted protein; n=2; Nematostella ve... 66 2e-10
UniRef50_UPI000065D5D5 Cluster: Transcription factor HES-3 (Hair... 65 5e-10
UniRef50_Q6JJ70 Cluster: Hairy/enhancer of split; n=1; Strongylo... 65 5e-10
UniRef50_Q9DEU7 Cluster: Transcription factor Her-8b; n=3; Danio... 64 1e-09
UniRef50_Q8T8A9 Cluster: Hairy E(SPL) like bHLH transcription fa... 64 1e-09
UniRef50_Q4H3P0 Cluster: Transcription factor protein; n=1; Cion... 63 2e-09
UniRef50_Q5XHC4 Cluster: LOC495039 protein; n=7; Tetrapoda|Rep: ... 62 4e-09
UniRef50_Q7KM13 Cluster: Hairy/enhancer-of-split related with YR... 62 4e-09
UniRef50_Q0VFM2 Cluster: Hairy and enhancer of split 6 gene 2; n... 61 7e-09
UniRef50_Q17LB7 Cluster: Transcription factor Hairy, putative; n... 61 1e-08
UniRef50_Q5S4J7 Cluster: Enhancer of split complex m5 protein; n... 60 1e-08
UniRef50_Q0P454 Cluster: Zgc:153398; n=6; Clupeocephala|Rep: Zgc... 60 2e-08
UniRef50_Q4H3P1 Cluster: Transcription factor protein; n=1; Cion... 60 2e-08
UniRef50_UPI0000E48019 Cluster: PREDICTED: similar to hairy/enha... 60 2e-08
UniRef50_Q1ECY5 Cluster: LOC565269 protein; n=3; Danio rerio|Rep... 60 2e-08
UniRef50_UPI0000F1EAFE Cluster: PREDICTED: hypothetical protein;... 59 3e-08
UniRef50_Q6YID3 Cluster: Hairy and enhancer of split; n=1; Helob... 59 3e-08
UniRef50_Q9VJ16 Cluster: CG10446-PA; n=4; Diptera|Rep: CG10446-P... 59 4e-08
UniRef50_UPI00015B46B7 Cluster: PREDICTED: similar to GA10322-PA... 58 5e-08
UniRef50_UPI0000D563AB Cluster: PREDICTED: similar to CG10446-PA... 58 5e-08
UniRef50_A7RYX3 Cluster: Predicted protein; n=1; Nematostella ve... 58 7e-08
UniRef50_UPI0000D5795D Cluster: PREDICTED: similar to CG11194-PA... 57 2e-07
UniRef50_UPI000058443F Cluster: PREDICTED: similar to hairy E pr... 57 2e-07
UniRef50_Q7T3J0 Cluster: Hairy and enhancer of split 5; n=3; Dan... 56 2e-07
UniRef50_UPI000059FC8B Cluster: PREDICTED: similar to hairy/enha... 56 3e-07
UniRef50_Q9UBP5 Cluster: Hairy/enhancer-of-split related with YR... 56 3e-07
UniRef50_A7S152 Cluster: Predicted protein; n=1; Nematostella ve... 56 4e-07
UniRef50_A7RYX2 Cluster: Predicted protein; n=1; Nematostella ve... 55 5e-07
UniRef50_Q6P0J1 Cluster: Hairy and enhancer of split 6; n=3; Dan... 55 6e-07
UniRef50_Q8AXV5 Cluster: Hairy/enhancer-of-split related with YR... 55 6e-07
UniRef50_Q8UW74 Cluster: HES-related 1A; n=4; Xenopus|Rep: HES-r... 54 1e-06
UniRef50_Q4S814 Cluster: Chromosome 9 SCAF14710, whole genome sh... 54 1e-06
UniRef50_Q4QRL6 Cluster: Hairy-related 12; n=2; Danio rerio|Rep:... 54 1e-06
UniRef50_A3KQ57 Cluster: Hairy and enhancer of split related-7; ... 54 1e-06
UniRef50_A1L3K9 Cluster: LOC100037036 protein; n=2; Xenopus|Rep:... 54 1e-06
UniRef50_Q6V6Y9 Cluster: Hairy H protein; n=2; Coelomata|Rep: Ha... 54 1e-06
UniRef50_Q4H3E4 Cluster: Transcription factor protein; n=1; Cion... 54 1e-06
UniRef50_UPI0000D5710A Cluster: PREDICTED: similar to CG10446-PA... 53 2e-06
UniRef50_UPI00005846BD Cluster: PREDICTED: similar to Hey1 prote... 53 2e-06
UniRef50_Q4RKD6 Cluster: Chromosome 21 SCAF15029, whole genome s... 53 2e-06
UniRef50_Q9Y5J3 Cluster: Hairy/enhancer-of-split related with YR... 53 2e-06
UniRef50_Q96HZ4 Cluster: Transcription cofactor HES-6; n=18; cel... 53 2e-06
UniRef50_Q7Q509 Cluster: ENSANGP00000020858; n=1; Anopheles gamb... 53 3e-06
UniRef50_Q9W7B6 Cluster: BHLH-WRPW transcription factor ESR-5; n... 52 5e-06
UniRef50_UPI00000181D8 Cluster: Homolog of Brachydanio rerio "Ha... 51 8e-06
UniRef50_Q96HZ4-2 Cluster: Isoform 2 of Q96HZ4 ; n=2; Catarrhini... 51 1e-05
UniRef50_A3KQ56 Cluster: Hairy-related 1; n=3; Danio rerio|Rep: ... 51 1e-05
UniRef50_Q9BYE0 Cluster: Transcription factor HES-7; n=11; Theri... 51 1e-05
UniRef50_UPI00015A7FE8 Cluster: hairy-related 1; n=3; Euteleosto... 50 1e-05
UniRef50_Q53U32 Cluster: Enhancer of split related protein 3/7b;... 50 1e-05
UniRef50_Q2TP33 Cluster: Her5; n=1; Oryzias latipes|Rep: Her5 - ... 50 1e-05
UniRef50_Q4W593 Cluster: ESR4; n=3; Xenopus|Rep: ESR4 - Xenopus ... 50 2e-05
UniRef50_O16853 Cluster: Lin-22; n=2; Caenorhabditis|Rep: Lin-22... 50 2e-05
UniRef50_Q9NQ87 Cluster: Hairy/enhancer-of-split related with YR... 50 2e-05
UniRef50_Q2TP34 Cluster: Her1-11; n=1; Oryzias latipes|Rep: Her1... 49 3e-05
UniRef50_A7SMU2 Cluster: Predicted protein; n=1; Nematostella ve... 48 6e-05
UniRef50_Q6QB00 Cluster: Her/Hey-like protein; n=2; Clupeocephal... 48 7e-05
UniRef50_Q5TYJ1 Cluster: ENSANGP00000029214; n=1; Anopheles gamb... 39 1e-04
UniRef50_UPI00015B47F2 Cluster: PREDICTED: similar to RT01017p; ... 47 1e-04
UniRef50_Q5D212 Cluster: Hairy and enhancer of split 5; n=10; Te... 47 1e-04
UniRef50_Q4S832 Cluster: Chromosome 9 SCAF14710, whole genome sh... 47 2e-04
UniRef50_A7S155 Cluster: Predicted protein; n=1; Nematostella ve... 47 2e-04
UniRef50_Q6W4T8 Cluster: Her11; n=3; Danio rerio|Rep: Her11 - Da... 46 2e-04
UniRef50_Q504H7 Cluster: Her5 protein; n=3; Danio rerio|Rep: Her... 46 3e-04
UniRef50_Q53U31 Cluster: Enhancer of split related protein 1b; n... 46 4e-04
UniRef50_Q90Z13 Cluster: Enhancer of split related 2; n=2; Xenop... 45 5e-04
UniRef50_Q9YI65 Cluster: Basic-helix-loop-helix transcription fa... 43 0.002
UniRef50_Q5TA89 Cluster: Transcription factor HES-5; n=11; Amnio... 43 0.002
UniRef50_UPI0000360D97 Cluster: Transcription factor HES-5 (Hair... 43 0.003
UniRef50_Q4V986 Cluster: Her4.2 protein; n=8; Danio rerio|Rep: H... 43 0.003
UniRef50_Q9PTN9 Cluster: Enhancer of split related epidermal pro... 42 0.004
UniRef50_Q28JA3 Cluster: Novel helix-loop-helix DNA binding doma... 42 0.004
UniRef50_Q1L7T5 Cluster: Her4; n=5; Percomorpha|Rep: Her4 - Oryz... 42 0.004
UniRef50_A6NFD8 Cluster: Uncharacterized protein ENSP00000343464... 36 0.006
UniRef50_Q688C9 Cluster: 213F14-1; n=9; Xenopus|Rep: 213F14-1 - ... 42 0.006
UniRef50_Q5TGS1 Cluster: Transcription factor HES-3; n=11; Euthe... 42 0.006
UniRef50_Q90464 Cluster: HER-2 protein; n=1; Danio rerio|Rep: HE... 41 0.011
UniRef50_UPI0000D9CBA5 Cluster: PREDICTED: similar to basic heli... 40 0.015
UniRef50_Q6GNE9 Cluster: LOC443665 protein; n=4; Xenopus|Rep: LO... 40 0.015
UniRef50_Q2L4U4 Cluster: BHLH protein DEC1b; n=5; Euteleostomi|R... 40 0.015
UniRef50_Q99PV5 Cluster: Class B basic helix-loop-helix protein ... 40 0.015
UniRef50_Q9C0J9 Cluster: Class B basic helix-loop-helix protein ... 40 0.015
UniRef50_O14503 Cluster: Class B basic helix-loop-helix protein ... 40 0.015
UniRef50_Q9VGZ5 Cluster: CG17100-PA; n=4; Sophophora|Rep: CG1710... 38 0.060
UniRef50_Q16SR7 Cluster: Class b basic helix-loop-helix protein;... 38 0.060
UniRef50_Q1L7T8 Cluster: Her7; n=1; Oryzias latipes|Rep: Her7 - ... 38 0.11
UniRef50_A7RYX5 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.11
UniRef50_Q6XLP6 Cluster: Hairy-related 9; n=2; Clupeocephala|Rep... 37 0.14
UniRef50_Q5KHD0 Cluster: Putative uncharacterized protein; n=2; ... 37 0.14
UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome s... 37 0.18
UniRef50_Q693N2 Cluster: Hairy; n=1; Clogmia albipunctata|Rep: H... 37 0.18
UniRef50_Q2H624 Cluster: Putative uncharacterized protein; n=1; ... 36 0.24
UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ... 35 0.56
UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -... 35 0.56
UniRef50_Q5M8T3 Cluster: HES5 protein; n=3; Eutheria|Rep: HES5 p... 34 0.98
UniRef50_Q6CD58 Cluster: Similarity; n=1; Yarrowia lipolytica|Re... 34 0.98
UniRef50_UPI0000DB76C3 Cluster: PREDICTED: similar to CG17100-PA... 34 1.3
UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep... 34 1.3
UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ... 34 1.3
UniRef50_Q693M9 Cluster: Hairy; n=1; Coboldia fuscipes|Rep: Hair... 34 1.3
UniRef50_Q4S869 Cluster: Chromosome 5 SCAF14709, whole genome sh... 33 1.7
UniRef50_A1SDB9 Cluster: Putative uncharacterized protein; n=1; ... 33 1.7
UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep: ... 33 2.3
UniRef50_A7RQW2 Cluster: Predicted protein; n=2; Nematostella ve... 33 3.0
UniRef50_UPI000155BBF4 Cluster: PREDICTED: similar to bHLH prote... 32 4.0
UniRef50_Q4S9E3 Cluster: Chromosome undetermined SCAF14699, whol... 32 4.0
UniRef50_Q5BVU6 Cluster: SJCHGC09047 protein; n=1; Schistosoma j... 32 4.0
UniRef50_Q13233 Cluster: Mitogen-activated protein kinase kinase... 31 6.9
UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob... 31 9.1
UniRef50_A6FPW1 Cluster: Serine/threonine protein phosphatase, p... 31 9.1
UniRef50_A2FG49 Cluster: Adenylate and Guanylate cyclase catalyt... 31 9.1
UniRef50_Q4PGA2 Cluster: Putative uncharacterized protein; n=1; ... 31 9.1
>UniRef50_Q7Q0A0 Cluster: ENSANGP00000020090; n=3;
Endopterygota|Rep: ENSANGP00000020090 - Anopheles
gambiae str. PEST
Length = 210
Score = 173 bits (422), Expect = 9e-43
Identities = 85/106 (80%), Positives = 89/106 (83%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+P+SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV
Sbjct: 6 EPLSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 65
Query: 275 XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
NP +D DRFRAGFTHAANEVSRCLAS PGVD+
Sbjct: 66 RHLHKLRRQQRLAANPVLDADRFRAGFTHAANEVSRCLASTPGVDI 111
>UniRef50_Q17DN9 Cluster: Enhancer of split protein, putative; n=3;
Endopterygota|Rep: Enhancer of split protein, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 229
Score = 170 bits (413), Expect = 1e-41
Identities = 83/106 (78%), Positives = 88/106 (83%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+P+SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV+KLEKADILELTV
Sbjct: 23 EPLSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVSKLEKADILELTV 82
Query: 275 XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
NP +D DRFRAGFTHAANEVSRCLAS GVD+
Sbjct: 83 RHLHKLRRQQRLTVNPVIDADRFRAGFTHAANEVSRCLASTQGVDI 128
>UniRef50_Q01070 Cluster: Enhancer of split mgamma protein
(E(spl)mgamma); n=13; Drosophila|Rep: Enhancer of split
mgamma protein (E(spl)mgamma) - Drosophila melanogaster
(Fruit fly)
Length = 205
Score = 122 bits (295), Expect = 2e-27
Identities = 62/108 (57%), Positives = 77/108 (71%), Gaps = 4/108 (3%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 274
+S+TYQYRKVMKPMLERKRRARIN+CLDELK+LMV+ L+SEGE+V +LEKADILELTV
Sbjct: 9 MSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTH 68
Query: 275 --XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
+ FR+G+ HA NEVSR L+ +PG++V
Sbjct: 69 LQKMKQQRQHKRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNV 116
>UniRef50_Q01069 Cluster: Enhancer of split mbeta protein
(E(spl)mbeta); n=5; Drosophila|Rep: Enhancer of split
mbeta protein (E(spl)mbeta) - Drosophila melanogaster
(Fruit fly)
Length = 195
Score = 122 bits (294), Expect = 3e-27
Identities = 65/116 (56%), Positives = 79/116 (68%), Gaps = 12/116 (10%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 274
+S+TYQYRKVMKPMLERKRRARIN+CLDELK++MV L EGE++ +LEKADILELTV
Sbjct: 7 MSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEH 66
Query: 275 -----XXXXXXXXXXXXXXNPSVD-----VDRFRAGFTHAANEVSRCLASIPGVDV 412
+PS D + FRAG+ HAANEVS+ LA++PGV V
Sbjct: 67 MKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSV 122
>UniRef50_Q01071 Cluster: Enhancer of split mdelta protein
(E(spl)mdelta); n=4; Sophophora|Rep: Enhancer of split
mdelta protein (E(spl)mdelta) - Drosophila melanogaster
(Fruit fly)
Length = 173
Score = 106 bits (254), Expect = 2e-22
Identities = 55/116 (47%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Frame = +2
Query: 77 LADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKAD 256
+A G + +++T YRKV KP+LERKRRAR+N LDELK+L+V + ++GE V+KLEKAD
Sbjct: 1 MAVQGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKAD 60
Query: 257 ILELTVXXXXXXXXXXXXXXN----PSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
ILELTV V++D+FRAG+T AA EVS +++PG+D+
Sbjct: 61 ILELTVNYLKAQQQQRVANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDL 116
>UniRef50_Q01068 Cluster: Enhancer of split m3 protein (E(spl)m3);
n=11; Sophophora|Rep: Enhancer of split m3 protein
(E(spl)m3) - Drosophila melanogaster (Fruit fly)
Length = 224
Score = 102 bits (245), Expect = 2e-21
Identities = 55/116 (47%), Positives = 72/116 (62%), Gaps = 13/116 (11%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 274
+S+TYQYRKVMKP+LERKRRARIN+CLD+LK+LMV LQ EGE+V +LEKADILELTV
Sbjct: 5 MSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDH 64
Query: 275 -----------XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+ V+ FR+G+ HAA+++++ L D
Sbjct: 65 MRKLKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD 120
>UniRef50_Q9N6W7 Cluster: HLHmdelta protein; n=1; Drosophila
hydei|Rep: HLHmdelta protein - Drosophila hydei (Fruit
fly)
Length = 158
Score = 89.0 bits (211), Expect = 3e-17
Identities = 50/112 (44%), Positives = 72/112 (64%)
Frame = +2
Query: 77 LADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKAD 256
+A +G + +++T YRKV KP+LERKRRAR+N LDELK+L+V + ++GE V+KLEKAD
Sbjct: 1 MAVEGQRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKAD 60
Query: 257 ILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
ILELTV + + + +T AA EVS +++PGVD+
Sbjct: 61 ILELTVNY---------------LKTQQQQRRYTQAAYEVSHIFSTVPGVDL 97
>UniRef50_UPI00003BFC0E Cluster: PREDICTED: similar to deadpan
CG8704-PA; n=2; Apocrita|Rep: PREDICTED: similar to
deadpan CG8704-PA - Apis mellifera
Length = 446
Score = 80.6 bits (190), Expect = 1e-14
Identities = 44/108 (40%), Positives = 67/108 (62%), Gaps = 3/108 (2%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
QP + R+ KP++E++RRARIN+CLDELK L++ A++ + +KLEKADILE+TV
Sbjct: 13 QPGMTKAELRRSNKPIMEKRRRARINQCLDELKSLILEAMKKDPARHSKLEKADILEMTV 72
Query: 275 ---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P+V + +FR+GF+ A EVSR ++ + VD
Sbjct: 73 KHLQAVQRQQLSTAVATDPAV-LTKFRSGFSECATEVSRYVSHLENVD 119
>UniRef50_Q9NFW8 Cluster: DNA-binding-protein hairy; n=2;
Entelegynae|Rep: DNA-binding-protein hairy - Cupiennius
salei (Wandering spider)
Length = 335
Score = 80.6 bits (190), Expect = 1e-14
Identities = 44/106 (41%), Positives = 66/106 (62%), Gaps = 3/106 (2%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-- 274
V++ + R+ KP++E++RRARIN L ELK L++ AL+ + +KLEKADILE+TV
Sbjct: 53 VTKCSETRRSTKPIMEKRRRARINNSLSELKNLILDALKKDNARHSKLEKADILEMTVKH 112
Query: 275 -XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+PS+ + +FRAGF ANEV+R + S+ G+D
Sbjct: 113 LQNLQMQQQQQQLTPDPSM-MAKFRAGFAECANEVNRFMGSMEGID 157
>UniRef50_Q26263 Cluster: Protein deadpan; n=3; Protostomia|Rep:
Protein deadpan - Drosophila melanogaster (Fruit fly)
Length = 435
Score = 80.2 bits (189), Expect = 2e-14
Identities = 44/109 (40%), Positives = 66/109 (60%), Gaps = 3/109 (2%)
Frame = +2
Query: 92 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 271
P +S+ + RK KP++E++RRARIN CL+ELK L++ A++ + KLEKADILE+T
Sbjct: 32 PNGLSKA-ELRKTNKPIMEKRRRARINHCLNELKSLILEAMKKDPARHTKLEKADILEMT 90
Query: 272 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
V +PSV V +F+ GF A EV+R ++ + G+D
Sbjct: 91 VKHLQSVQRQQLNMAIQSDPSV-VQKFKTGFVECAEEVNRYVSQMDGID 138
>UniRef50_P13098 Cluster: Enhancer of split m8 protein (E(spl)m8);
n=40; Drosophila|Rep: Enhancer of split m8 protein
(E(spl)m8) - Drosophila melanogaster (Fruit fly)
Length = 179
Score = 79.0 bits (186), Expect = 3e-14
Identities = 42/104 (40%), Positives = 66/104 (63%), Gaps = 1/104 (0%)
Frame = +2
Query: 104 SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILE-LTVXX 280
++T Y+KV KPMLER+RRAR+N+CLD LK L V+ L+ + + + +++KA++LE +
Sbjct: 5 TKTQIYQKVKKPMLERQRRARMNKCLDNLKTL-VAELRGD-DGILRMDKAEMLESAVIFM 62
Query: 281 XXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
S+ +D F+ G+ +A NEVSR +AS PG+ V
Sbjct: 63 RQQKTPKKVAQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSV 106
>UniRef50_Q29G34 Cluster: GA19235-PA; n=1; Drosophila
pseudoobscura|Rep: GA19235-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 217
Score = 77.8 bits (183), Expect = 8e-14
Identities = 38/60 (63%), Positives = 45/60 (75%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
Q +SR+ +YRKVMKP+LERKRRARIN CLDELK ++ E + KLEKADILEL V
Sbjct: 81 QGLSRSSEYRKVMKPLLERKRRARINNCLDELKIIIADLAHMETTGLNKLEKADILELAV 140
>UniRef50_UPI00015B599D Cluster: PREDICTED: similar to hairy
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to hairy protein - Nasonia vitripennis
Length = 376
Score = 77.4 bits (182), Expect = 1e-13
Identities = 42/100 (42%), Positives = 63/100 (63%), Gaps = 3/100 (3%)
Frame = +2
Query: 92 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 271
P R+ + R+ KP++E++RRARIN CL++LK L++ A++ + +KLEKADILE+T
Sbjct: 47 PAAPRRSSENRRSNKPIMEKRRRARINNCLNDLKALILDAMKKDPARHSKLEKADILEMT 106
Query: 272 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSR 382
V +P+V +++FRAGFT ANEV R
Sbjct: 107 VKHLETLQRQQVALASATDPNV-LNKFRAGFTECANEVGR 145
>UniRef50_Q14469 Cluster: Transcription factor HES-1; n=52;
Euteleostomi|Rep: Transcription factor HES-1 - Homo
sapiens (Human)
Length = 280
Score = 77.4 bits (182), Expect = 1e-13
Identities = 43/109 (39%), Positives = 65/109 (59%), Gaps = 3/109 (2%)
Frame = +2
Query: 92 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 271
P ++RK KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+T
Sbjct: 25 PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84
Query: 272 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
V +PSV + ++RAGF+ NEV+R L++ GV+
Sbjct: 85 VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVN 132
>UniRef50_Q90468 Cluster: HER-6 protein; n=4; Clupeocephala|Rep:
HER-6 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 334
Score = 75.8 bits (178), Expect = 3e-13
Identities = 42/109 (38%), Positives = 65/109 (59%), Gaps = 3/109 (2%)
Frame = +2
Query: 92 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 271
P ++RK KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+T
Sbjct: 89 PDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMT 148
Query: 272 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
V +P+V + ++RAGF+ NEV+R L++ GV+
Sbjct: 149 VKHLRNMQRAQMTAALNTDPTV-LGKYRAGFSECMNEVTRFLSTCEGVN 196
>UniRef50_UPI00003C06C0 Cluster: PREDICTED: similar to Protein
hairy; n=1; Apis mellifera|Rep: PREDICTED: similar to
Protein hairy - Apis mellifera
Length = 363
Score = 74.9 bits (176), Expect = 6e-13
Identities = 43/104 (41%), Positives = 65/104 (62%), Gaps = 3/104 (2%)
Frame = +2
Query: 107 RTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---X 277
R+ + R+ KP++E++RRARIN CL++LK L++ A++ + +KLEKADILE+TV
Sbjct: 45 RSGENRRSNKPIMEKRRRARINNCLNDLKTLILDAMKKDPARHSKLEKADILEMTVKHLE 104
Query: 278 XXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P+V +++FRAGFT A EV R PG+D
Sbjct: 105 TLQRQQVALAAATDPNV-LNKFRAGFTECAGEVGR----FPGLD 143
>UniRef50_Q9VWX7 Cluster: CG5927-PA; n=1; Drosophila
melanogaster|Rep: CG5927-PA - Drosophila melanogaster
(Fruit fly)
Length = 149
Score = 74.9 bits (176), Expect = 6e-13
Identities = 32/57 (56%), Positives = 45/57 (78%)
Frame = +2
Query: 104 SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
SR++QYR+V KPM+ERKRR+RINRCLD +K+L+ +GE +AK++ D+LEL V
Sbjct: 16 SRSHQYREVFKPMMERKRRSRINRCLDFIKDLLQEVSHLDGETMAKMDMGDVLELAV 72
>UniRef50_Q16NK4 Cluster: Hairy protein; n=4; Diptera|Rep: Hairy
protein - Aedes aegypti (Yellowfever mosquito)
Length = 343
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/100 (43%), Positives = 62/100 (62%), Gaps = 4/100 (4%)
Frame = +2
Query: 95 QPV-SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 271
QPV R R+ KP++E++RRARIN CL+ELK L++ A++ + +KLEKADILE+T
Sbjct: 26 QPVVKRPSDNRRSNKPIMEKRRRARINNCLNELKTLILDAMKKDPARHSKLEKADILEMT 85
Query: 272 V---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSR 382
V +P+V +++F+AGF A EVSR
Sbjct: 86 VKHLENLQRQQNAMSQATDPNV-MNKFKAGFNECAQEVSR 124
>UniRef50_Q208Q9 Cluster: AmphiHairyA; n=6; Branchiostoma
floridae|Rep: AmphiHairyA - Branchiostoma floridae
(Florida lancelet) (Amphioxus)
Length = 300
Score = 73.7 bits (173), Expect = 1e-12
Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 2/100 (2%)
Frame = +2
Query: 116 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXX 289
Q RK KP++E++RRARIN L++LK L++ AL+ + +KLEKADILE+TV
Sbjct: 19 QRRKSSKPIMEKRRRARINDSLNQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQ 78
Query: 290 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
V + ++RAG++ EVSR L GVD
Sbjct: 79 RQQIADAVIRDPVALSKYRAGYSECMTEVSRFLTGSDGVD 118
>UniRef50_A2TIR6 Cluster: Splhairy; n=1; Panulirus argus|Rep:
Splhairy - Panulirus argus (Spiny lobster)
Length = 253
Score = 73.7 bits (173), Expect = 1e-12
Identities = 41/91 (45%), Positives = 53/91 (58%), Gaps = 2/91 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-XXXXXXXX 298
R+ KP++E+KRR RIN CL++LK L++ L+ + KLEKADILE+TV
Sbjct: 20 RRTNKPIMEKKRRQRINDCLNQLKNLVLEGLKKDPSRYNKLEKADILEMTVRHVQALHRH 79
Query: 299 XXXXXXNPSVD-VDRFRAGFTHAANEVSRCL 388
P VD +FRAGF H A EV R L
Sbjct: 80 ESALSRQPPVDAAAKFRAGFAHCAAEVGRFL 110
>UniRef50_Q4H3N9 Cluster: Transcription factor protein; n=3;
Eumetazoa|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 522
Score = 73.3 bits (172), Expect = 2e-12
Identities = 43/112 (38%), Positives = 67/112 (59%), Gaps = 4/112 (3%)
Frame = +2
Query: 89 GPQPVSRTY-QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILE 265
G + TY + +K KP++E++RRARIN L+ELK +++ AL+ + +KLEKADILE
Sbjct: 19 GDVDLGGTYIERQKSSKPIMEKRRRARINSSLNELKSILLEALKKDSTRHSKLEKADILE 78
Query: 266 LTVXXXXXXXXXXXXXXNPSVD---VDRFRAGFTHAANEVSRCLASIPGVDV 412
+TV + S+D +++++AGF NEV R L++ GV V
Sbjct: 79 MTV-KYLKNVERQRLSVSLSIDPAEINQYKAGFNECRNEVMRFLSTCEGVTV 129
>UniRef50_Q6V6Z0 Cluster: Hairy G protein; n=1; Branchiostoma
floridae|Rep: Hairy G protein - Branchiostoma floridae
(Florida lancelet) (Amphioxus)
Length = 267
Score = 72.5 bits (170), Expect = 3e-12
Identities = 38/101 (37%), Positives = 59/101 (58%), Gaps = 2/101 (1%)
Frame = +2
Query: 113 YQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXX 286
YQ RK KP++E++RRARIN L+ELK L++ +++ + +KLEKADILE+ V
Sbjct: 13 YQSRKSSKPLMEKRRRARINSSLNELKNLILDTYKNDSTHHSKLEKADILEIAVKHVRSL 72
Query: 287 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+ R+RAG++ EV+R + ++ GVD
Sbjct: 73 QRQQMAAAVSTDPAALGRYRAGYSRCRAEVARFMGTVDGVD 113
>UniRef50_P29303 Cluster: Protein hairy; n=2; Muscomorpha|Rep:
Protein hairy - Drosophila virilis (Fruit fly)
Length = 378
Score = 72.5 bits (170), Expect = 3e-12
Identities = 42/99 (42%), Positives = 60/99 (60%), Gaps = 3/99 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXX 292
R+ KP++E++RRARIN CL+ELK L++ A + + +KLEKADILE TV
Sbjct: 38 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ 97
Query: 293 XXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P + +++F+AGF ANEVSR PG+D
Sbjct: 98 QAAMQQAADPKI-INKFKAGFADCANEVSR----FPGLD 131
>UniRef50_Q8T306 Cluster: Helix-loop-helix transcription factor;
n=2; Tribolium castaneum|Rep: Helix-loop-helix
transcription factor - Tribolium castaneum (Red flour
beetle)
Length = 249
Score = 72.1 bits (169), Expect = 4e-12
Identities = 44/104 (42%), Positives = 62/104 (59%), Gaps = 3/104 (2%)
Frame = +2
Query: 107 RTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---X 277
R R+ KP++E++RRARIN L+ELK L++ A++ + +KLEKADILE+TV
Sbjct: 30 RVSDNRRSNKPIMEKRRRARINNSLNELKTLILDAMKKDPARHSKLEKADILEMTVKHLQ 89
Query: 278 XXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+PSV V +FRAGF+ A+EV R PG+D
Sbjct: 90 NLQRQQAAMSAATDPSV-VSKFRAGFSECASEVGR----FPGLD 128
>UniRef50_UPI0001554A1E Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 287
Score = 71.3 bits (167), Expect = 7e-12
Identities = 39/95 (41%), Positives = 60/95 (63%), Gaps = 3/95 (3%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXXXXXX 304
KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+TV
Sbjct: 21 KPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTA 80
Query: 305 XXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P+V + ++RAGF+ NEV+R L++ GV+
Sbjct: 81 ALSSDPTV-LGKYRAGFSECMNEVTRFLSTCEGVN 114
>UniRef50_Q17DP5 Cluster: Hairy protein; n=2; Culicidae|Rep: Hairy
protein - Aedes aegypti (Yellowfever mosquito)
Length = 343
Score = 71.3 bits (167), Expect = 7e-12
Identities = 39/101 (38%), Positives = 61/101 (60%), Gaps = 3/101 (2%)
Frame = +2
Query: 116 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 286
+ RK KP++E+KRRARIN L++LK L++ A++ + +KLEKADIL+LTV
Sbjct: 27 EIRKTNKPIMEKKRRARINNYLNDLKALLLDAMKKDPIRHSKLEKADILDLTVKHLQDLE 86
Query: 287 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P+V VD+F++GF E+ + L ++ VD
Sbjct: 87 RRKLAIAMAVDPTV-VDKFKSGFNECIEEIDKYLNTVSSVD 126
>UniRef50_UPI0000D57461 Cluster: PREDICTED: similar to CG8704-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8704-PA - Tribolium castaneum
Length = 371
Score = 70.5 bits (165), Expect = 1e-11
Identities = 37/92 (40%), Positives = 56/92 (60%), Gaps = 3/92 (3%)
Frame = +2
Query: 116 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 286
+ RK KP++E++RRARIN CL+E+K L++ A+ + +KLEKADILE+ V
Sbjct: 23 ELRKTHKPIMEKRRRARINHCLNEIKTLILEAMNKDPARHSKLEKADILEMAVKHLQNVQ 82
Query: 287 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSR 382
+PSV + +F++GF ANE+ R
Sbjct: 83 RQQLAVAMASDPSV-LRKFKSGFNECANEIDR 113
>UniRef50_P14003 Cluster: Protein hairy; n=3; Sophophora|Rep:
Protein hairy - Drosophila melanogaster (Fruit fly)
Length = 337
Score = 70.5 bits (165), Expect = 1e-11
Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 3/99 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXX 292
R+ KP++E++RRARIN CL+ELK L++ A + + +KLEKADILE TV
Sbjct: 32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ 91
Query: 293 XXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P + V++F+AGF NEVSR PG++
Sbjct: 92 QAAMQQAADPKI-VNKFKAGFADCVNEVSR----FPGIE 125
>UniRef50_Q6V6Z2 Cluster: Hairy E protein; n=3; Branchiostoma
floridae|Rep: Hairy E protein - Branchiostoma floridae
(Florida lancelet) (Amphioxus)
Length = 345
Score = 69.7 bits (163), Expect = 2e-11
Identities = 43/108 (39%), Positives = 62/108 (57%), Gaps = 3/108 (2%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
Q SR + RK KP++E++RRARIN L++LK L++ AL+ + +KLEKADILE+TV
Sbjct: 4 QKDSRPSEGRKSSKPIMEKRRRARINDSLNQLKTLILDALKKDSSRHSKLEKADILEMTV 63
Query: 275 ---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+P+V + ++RAGF EVS L S V+
Sbjct: 64 KHLRNLQRQHVAAAVSTDPNV-LGQYRAGFNECMTEVSSFLGSASTVE 110
>UniRef50_A7RU73 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 68.9 bits (161), Expect = 4e-11
Identities = 42/101 (41%), Positives = 60/101 (59%), Gaps = 4/101 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV----XXXXX 289
RK KPM+E++RRARIN+ L+ELK L++ A++ + +KLEKADILE+TV
Sbjct: 18 RKSSKPMMEKRRRARINQSLNELKILILEAMKKDTSCYSKLEKADILEMTVKYLRAMKTT 77
Query: 290 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
+PS V ++RAGF A EV+R + VD+
Sbjct: 78 QQLTGIVPSDPS-SVAQYRAGFNECALEVTRYFMANDNVDL 117
>UniRef50_Q56KF1 Cluster: Enhancer of split m5 protein; n=2;
Drosophila melanogaster|Rep: Enhancer of split m5
protein - Drosophila melanogaster (Fruit fly)
Length = 129
Score = 67.7 bits (158), Expect = 9e-11
Identities = 52/104 (50%), Positives = 73/104 (70%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXX 280
VS+T Y KV KP+LER+RRAR+N+CLD LK L V+ Q + + + +++KA++LE
Sbjct: 11 VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTL-VAEFQGD-DAILRMDKAEMLE-AAXX 67
Query: 281 XXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
D F+ G+ +A +E+SR +A P + V
Sbjct: 68 XXXXXXXXXXXXXXXXXXDSFKNGYMNAVSEISRVMACTPAMSV 111
>UniRef50_Q9Y543 Cluster: Transcription factor HES-2; n=14;
Theria|Rep: Transcription factor HES-2 - Homo sapiens
(Human)
Length = 173
Score = 67.3 bits (157), Expect = 1e-10
Identities = 36/99 (36%), Positives = 55/99 (55%)
Frame = +2
Query: 92 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 271
P+ + RK +KP+LE++RRARIN+ L +LK L++ L E N +KLEKAD+LE+T
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
Query: 272 VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCL 388
V P + D +R G++ ++R L
Sbjct: 64 VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVL 101
>UniRef50_Q568C3 Cluster: Her3 protein; n=3; Danio rerio|Rep: Her3
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 253
Score = 66.5 bits (155), Expect = 2e-10
Identities = 50/126 (39%), Positives = 67/126 (53%)
Frame = +2
Query: 11 SAQTYTFTEHTMSTMSYEIAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDEL 190
S+ + TEH + TM+ + S A PQ V +KV KP++E+KRRARIN+CL++L
Sbjct: 12 SSGFFKHTEH-LRTMA-AASNSAATAKPQNV------KKVSKPLMEKKRRARINKCLNQL 63
Query: 191 KELMVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAAN 370
K L+ SA S KLEKADILELTV + + D + AG+ N
Sbjct: 64 KSLLESAC-SNNIRKRKLEKADILELTV-KHLRHLQNTKRGLSKACDSAEYHAGYRSCLN 121
Query: 371 EVSRCL 388
VS L
Sbjct: 122 TVSHYL 127
>UniRef50_A7RYX4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 213
Score = 66.5 bits (155), Expect = 2e-10
Identities = 39/90 (43%), Positives = 50/90 (55%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
RK KPM+E+ RRARIN L+ELK L++ L + +K+EKADILE+TV
Sbjct: 20 RKAKKPMMEKLRRARINDSLNELKVLVLELLNKDASRYSKMEKADILEMTVGYLRAAQRI 79
Query: 302 XXXXXNPSVDVDRFRAGFTHAANEVSRCLA 391
+ D FRAGF A EVS L+
Sbjct: 80 EKRTQGSTPPSD-FRAGFNACAVEVSNRLS 108
>UniRef50_UPI000065D5D5 Cluster: Transcription factor HES-3 (Hairy
and enhancer of split 3).; n=1; Takifugu rubripes|Rep:
Transcription factor HES-3 (Hairy and enhancer of split
3). - Takifugu rubripes
Length = 271
Score = 65.3 bits (152), Expect = 5e-10
Identities = 45/118 (38%), Positives = 65/118 (55%), Gaps = 3/118 (2%)
Frame = +2
Query: 65 IAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKL 244
+A + ++D P+ VS +KV KP++E+KRRARIN+CLD+LK +++ + S KL
Sbjct: 2 VATTDSEDPPKHVSG----KKVSKPLMEKKRRARINKCLDQLK-ILLESYYSTSIRKRKL 56
Query: 245 EKADILELTVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLA---SIPGVD 409
EKADILELTV S D ++GF A V + L S+ G+D
Sbjct: 57 EKADILELTVNHLRNLQKHQSCNIASSESSDH-QSGFRRCAANVDQFLLMADSVNGID 113
>UniRef50_Q6JJ70 Cluster: Hairy/enhancer of split; n=1;
Strongylocentrotus purpuratus|Rep: Hairy/enhancer of
split - Strongylocentrotus purpuratus (Purple sea
urchin)
Length = 400
Score = 65.3 bits (152), Expect = 5e-10
Identities = 40/118 (33%), Positives = 61/118 (51%), Gaps = 3/118 (2%)
Frame = +2
Query: 62 EIAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAK 241
E+ +S +P RK KP +E++RRARIN L +LK L++ A + +K
Sbjct: 5 EVYFSKMPVDTKPKIHEGSGRKSSKPQMEKRRRARINDSLGQLKALILEATNKDSSRHSK 64
Query: 242 LEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGV 406
LEKADILE+TV +P++ V RFR G++ +EV+R +I +
Sbjct: 65 LEKADILEMTVKHLRNIQRNQLTGPLSSDPNM-VSRFRQGYSECVHEVARFFTNIENI 121
>UniRef50_Q9DEU7 Cluster: Transcription factor Her-8b; n=3; Danio
rerio|Rep: Transcription factor Her-8b - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 221
Score = 64.1 bits (149), Expect = 1e-09
Identities = 39/113 (34%), Positives = 59/113 (52%), Gaps = 5/113 (4%)
Frame = +2
Query: 86 DGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILE 265
+GP+ + RK+ KP++E+KRR RIN L++LK +MV A + +KLEKAD+LE
Sbjct: 8 NGPEKNFNAKEERKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLD---QSKLEKADVLE 64
Query: 266 LTVXXXXXXXXXXXXXXNPSVDV-----DRFRAGFTHAANEVSRCLASIPGVD 409
+TV + S R+ +G+ +EV L S PG+D
Sbjct: 65 ITVQHMENLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMD 117
>UniRef50_Q8T8A9 Cluster: Hairy E(SPL) like bHLH transcription
factor; n=1; Halocynthia roretzi|Rep: Hairy E(SPL) like
bHLH transcription factor - Halocynthia roretzi (Sea
squirt)
Length = 292
Score = 63.7 bits (148), Expect = 1e-09
Identities = 31/51 (60%), Positives = 39/51 (76%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK KP++E+KRR RINRCLDELK +++ A+ E KLEKADILE+TV
Sbjct: 14 RKTNKPIMEKKRRERINRCLDELKNIVLRAVNEE-SRPNKLEKADILEMTV 63
>UniRef50_Q4H3P0 Cluster: Transcription factor protein; n=1; Ciona
intestinalis|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 333
Score = 63.3 bits (147), Expect = 2e-09
Identities = 37/93 (39%), Positives = 55/93 (59%), Gaps = 4/93 (4%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV-AKLEKADILELTV---XXXXX 289
R+ KP++E++RR RIN+ L+ELK +++ AL+ + +KLEKADILE+TV
Sbjct: 25 RRASKPLMEKRRRERINKSLNELKSILLHALRKDQSTCHSKLEKADILEMTVRYLRGIQR 84
Query: 290 XXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCL 388
+PSV V ++R G+ NEVS L
Sbjct: 85 QRMNAAITLDPSV-VSKYRNGYVECKNEVSHFL 116
>UniRef50_Q5XHC4 Cluster: LOC495039 protein; n=7; Tetrapoda|Rep:
LOC495039 protein - Xenopus laevis (African clawed frog)
Length = 202
Score = 62.1 bits (144), Expect = 4e-09
Identities = 31/73 (42%), Positives = 49/73 (67%), Gaps = 3/73 (4%)
Frame = +2
Query: 65 IAYSLADDGPQPVSRTYQ---YRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV 235
+A S+ + P+P R + RK +KP++E++RRARIN L++LK L++ + +
Sbjct: 18 LADSMHNYQPKPGKRNQEASELRKTLKPLMEKRRRARINESLNQLKTLILPLIGKDNSRY 77
Query: 236 AKLEKADILELTV 274
+KLEKADILE+TV
Sbjct: 78 SKLEKADILEMTV 90
>UniRef50_Q7KM13 Cluster: Hairy/enhancer-of-split related with YRPW
motif protein; n=2; Sophophora|Rep:
Hairy/enhancer-of-split related with YRPW motif protein
- Drosophila melanogaster (Fruit fly)
Length = 425
Score = 62.1 bits (144), Expect = 4e-09
Identities = 42/109 (38%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+P S RK + ++E+KRR RIN L ELK L+ SA + +G AKLEKA+IL+LTV
Sbjct: 92 EPGSCQLMSRKKRRGVIEKKRRDRINSSLTELKRLVPSAYEKQGS--AKLEKAEILQLTV 149
Query: 275 XXXXXXXXXXXXXXN---PSVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
+ V +D GF A EV+R L +I G+D+
Sbjct: 150 EHLKSLQSKTLDSLSYDPQRVAMDYHIIGFRECAAEVARYLVTIEGMDI 198
>UniRef50_Q0VFM2 Cluster: Hairy and enhancer of split 6 gene 2; n=6;
Coelomata|Rep: Hairy and enhancer of split 6 gene 2 -
Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 189
Score = 61.3 bits (142), Expect = 7e-09
Identities = 37/99 (37%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
RK+ KP++ERKRR RIN CL++LKE ++ A + +KLEKADILE+TV
Sbjct: 18 RKLRKPLIERKRRERINTCLEQLKETVIKAFHLD---QSKLEKADILEMTVRHLQNIQKS 74
Query: 302 XXXXXNPSVDVD---RFRAGFTHAANEVSRCLASIPGVD 409
VD RF G+ +E+ L + +D
Sbjct: 75 KSTGEPSQGSVDAQQRFSTGYIQCMHELHSLLLTCDWMD 113
>UniRef50_Q17LB7 Cluster: Transcription factor Hairy, putative; n=2;
Culicidae|Rep: Transcription factor Hairy, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 298
Score = 60.9 bits (141), Expect = 1e-08
Identities = 43/102 (42%), Positives = 55/102 (53%), Gaps = 5/102 (4%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
RK + ++E+KRR RIN L ELK L+ SA + +G AKLEKA+IL+LTV
Sbjct: 20 RKRRRGVIEKKRRDRINSSLSELKRLVPSAYEKQGS--AKLEKAEILQLTV--DHLKQLH 75
Query: 302 XXXXXNPSVDVDRFR-----AGFTHAANEVSRCLASIPGVDV 412
+ S D RF GF EV+R L SI G+DV
Sbjct: 76 ARGLDDASYDPQRFAMDYHIIGFRECVAEVARYLVSIEGMDV 117
>UniRef50_Q5S4J7 Cluster: Enhancer of split complex m5 protein; n=2;
Drosophila melanogaster|Rep: Enhancer of split complex
m5 protein - Drosophila melanogaster (Fruit fly)
Length = 178
Score = 60.5 bits (140), Expect = 1e-08
Identities = 33/88 (37%), Positives = 54/88 (61%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXX 280
VS+T Y KV KP+LER+RRAR+N+CLD LK L V+ Q + + + +++KA++LE +
Sbjct: 12 VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTL-VAEFQGD-DAILRMDKAEMLEAALVF 69
Query: 281 XXXXXXXXXXXXNPSVDVDRFRAGFTHA 364
+P + +D F+ G+ +A
Sbjct: 70 MRKQVVKQQAPVSP-LPMDSFKNGYMNA 96
>UniRef50_Q0P454 Cluster: Zgc:153398; n=6; Clupeocephala|Rep:
Zgc:153398 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 172
Score = 60.1 bits (139), Expect = 2e-08
Identities = 29/53 (54%), Positives = 38/53 (71%)
Frame = +2
Query: 116 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+ RK +KP+LE+KRRARIN LD LK L++ + +KLEKADILE+TV
Sbjct: 7 ELRKTLKPLLEKKRRARINDSLDRLKALILPLTGKDNCRYSKLEKADILEMTV 59
>UniRef50_Q4H3P1 Cluster: Transcription factor protein; n=1; Ciona
intestinalis|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 28/51 (54%), Positives = 41/51 (80%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK KP++E+KRR RIN+CL++LK ++++A+ +E KLEKADILE+TV
Sbjct: 14 RKTNKPIMEKKRRERINKCLEDLKSIVLTAV-AEESRPNKLEKADILEMTV 63
>UniRef50_UPI0000E48019 Cluster: PREDICTED: similar to
hairy/enhancer of split; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to hairy/enhancer of
split - Strongylocentrotus purpuratus
Length = 383
Score = 59.7 bits (138), Expect = 2e-08
Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Frame = +2
Query: 98 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 274
P + + +KP +E++RRARIN L +LK L++ AL +KLEKADILE+TV
Sbjct: 23 PTDDQHPPSRSLKPQMEKRRRARINDSLLQLKNLVLDALNKNNPRHSKLEKADILEMTVR 82
Query: 275 --XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCL 388
N ++ +++ G+ EVSR L
Sbjct: 83 YLRSIHRQQLSGIGSHNEQANIAQYQTGYAECMREVSRYL 122
>UniRef50_Q1ECY5 Cluster: LOC565269 protein; n=3; Danio rerio|Rep:
LOC565269 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 223
Score = 59.7 bits (138), Expect = 2e-08
Identities = 29/51 (56%), Positives = 39/51 (76%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK+ KP++ERKRR RIN CLD+L+E +V + + +KLEKADILE+TV
Sbjct: 35 RKLRKPLIERKRRERINLCLDQLRETVVGVFKPD---QSKLEKADILEMTV 82
>UniRef50_UPI0000F1EAFE Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 195
Score = 59.3 bits (137), Expect = 3e-08
Identities = 26/54 (48%), Positives = 40/54 (74%)
Frame = +2
Query: 113 YQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++ RK +KP++E++RRARIN L+ LK L++ + + +KLEKADILE+TV
Sbjct: 27 HELRKTLKPLMEKRRRARINDSLNHLKTLILPLVGKDASRYSKLEKADILEMTV 80
>UniRef50_Q6YID3 Cluster: Hairy and enhancer of split; n=1;
Helobdella robusta|Rep: Hairy and enhancer of split -
Helobdella robusta (Leech)
Length = 435
Score = 59.3 bits (137), Expect = 3e-08
Identities = 29/58 (50%), Positives = 40/58 (68%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
VSR Q RK+ KP++E+KRR RIN LD+LK L++ A + ++EKADILE+ V
Sbjct: 5 VSRD-QLRKIKKPIIEKKRRERINESLDQLKNLVLEATNKDASMYNRMEKADILEMAV 61
>UniRef50_Q9VJ16 Cluster: CG10446-PA; n=4; Diptera|Rep: CG10446-PA -
Drosophila melanogaster (Fruit fly)
Length = 507
Score = 58.8 bits (136), Expect = 4e-08
Identities = 40/98 (40%), Positives = 61/98 (62%), Gaps = 7/98 (7%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSE----GENVA---KLEKADILELTVXX 280
++ KP++E++RRARIN+ L LK L++ + +++ GE A KLEKADILELTV
Sbjct: 51 KRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKADILELTV-- 108
Query: 281 XXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLAS 394
+P+ V+++RAG+T A EV+R LA+
Sbjct: 109 --RHFQRHRNLDDPT--VNKYRAGYTDCAREVARYLAT 142
>UniRef50_UPI00015B46B7 Cluster: PREDICTED: similar to GA10322-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10322-PA - Nasonia vitripennis
Length = 715
Score = 58.4 bits (135), Expect = 5e-08
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXX 313
KP++E++RRARIN+ L LK L++ + + E +KLEKADILELTV
Sbjct: 330 KPLMEKRRRARINQSLAALKALILDSARLENTKHSKLEKADILELTV----RHLQRQRSL 385
Query: 314 XNPSVDVDRFRAGFTHAANEVSRCL 388
P + R++AG+ + EVSR L
Sbjct: 386 AQPG--LSRYKAGYQDCSREVSRYL 408
>UniRef50_UPI0000D563AB Cluster: PREDICTED: similar to CG10446-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10446-PA - Tribolium castaneum
Length = 232
Score = 58.4 bits (135), Expect = 5e-08
Identities = 34/94 (36%), Positives = 52/94 (55%)
Frame = +2
Query: 107 RTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXX 286
R + R+ KP++E++RRARIN+ L LK L++ + +++ +KLEKADILELTV
Sbjct: 7 RASEPRRANKPLMEKRRRARINQSLAALKTLILDSAKADNTKHSKLEKADILELTVRHFQ 66
Query: 287 XXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCL 388
V +++AG+ EV R L
Sbjct: 67 RHRSLDIK------GVHQYKAGYADCVREVQRYL 94
>UniRef50_A7RYX3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 58.0 bits (134), Expect = 7e-08
Identities = 28/51 (54%), Positives = 38/51 (74%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
R++MKP+ ER RR RIN L ELK L++SAL + +++EKADILE+TV
Sbjct: 23 RRIMKPITERLRRERINSSLKELKFLVLSALGQDVSRYSRMEKADILEMTV 73
>UniRef50_UPI0000D5795D Cluster: PREDICTED: similar to CG11194-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11194-PA - Tribolium castaneum
Length = 363
Score = 56.8 bits (131), Expect = 2e-07
Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 295
RK + ++E+KRR RIN L ELK L+ SA + +G AKLEKA+IL++TV
Sbjct: 116 RKKRRGVIEKKRRDRINMSLSELKRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAK 173
Query: 296 XXXXXXXNP-SVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
+P +D GF EV+R L I G+DV
Sbjct: 174 GLDAFTYDPHKYAMDYHGMGFRECVAEVARYLERIEGLDV 213
>UniRef50_UPI000058443F Cluster: PREDICTED: similar to hairy E
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to hairy E protein -
Strongylocentrotus purpuratus
Length = 397
Score = 56.8 bits (131), Expect = 2e-07
Identities = 39/105 (37%), Positives = 58/105 (55%), Gaps = 5/105 (4%)
Frame = +2
Query: 104 SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVA--KLEKADILELT-- 271
SR+++ RK KP++E++RRARIN CL EL+ ++ AL E + K EKADILE T
Sbjct: 8 SRSHEGRKSSKPLMEKRRRARINDCLTELQTIL-DALNPENNSTRQNKREKADILEQTVK 66
Query: 272 -VXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPG 403
V +P+ V +FR+GF V++ L++ G
Sbjct: 67 LVKQLRQHGIRGNHPPDPNTQV-QFRSGFNECMATVTQFLSANNG 110
>UniRef50_Q7T3J0 Cluster: Hairy and enhancer of split 5; n=3; Danio
rerio|Rep: Hairy and enhancer of split 5 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 149
Score = 56.4 bits (130), Expect = 2e-07
Identities = 26/50 (52%), Positives = 37/50 (74%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ KP++E+ RR RIN C+++LK ++ Q + N AKLEKADILE+TV
Sbjct: 19 KLRKPVVEKMRRDRINNCIEQLKSMLEKEFQQQDPN-AKLEKADILEMTV 67
>UniRef50_UPI000059FC8B Cluster: PREDICTED: similar to
hairy/enhancer-of-split related with YRPW motif 2; n=1;
Canis lupus familiaris|Rep: PREDICTED: similar to
hairy/enhancer-of-split related with YRPW motif 2 -
Canis familiaris
Length = 424
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 295
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 265 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 322
Query: 296 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
++ +D GF EV+R L+S+ G+D
Sbjct: 323 GGKGYFDAHALALDFMSIGFRECLGEVARYLSSVEGLD 360
>UniRef50_Q9UBP5 Cluster: Hairy/enhancer-of-split related with YRPW
motif protein 2; n=20; Euteleostomi|Rep:
Hairy/enhancer-of-split related with YRPW motif protein
2 - Homo sapiens (Human)
Length = 337
Score = 56.0 bits (129), Expect = 3e-07
Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 295
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 296 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
++ +D GF EV+R L+S+ G+D
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLD 144
>UniRef50_A7S152 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 170
Score = 55.6 bits (128), Expect = 4e-07
Identities = 32/55 (58%), Positives = 42/55 (76%), Gaps = 5/55 (9%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSAL-----QSEGENVAKLEKADILELTV 274
K KP+LER+RRARIN L+ELK L++S+L Q+E +N K+EKA+ILELTV
Sbjct: 20 KSSKPLLERQRRARINHSLNELKTLVLSSLYQNCPQAE-QNCEKMEKAEILELTV 73
>UniRef50_A7RYX2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 233
Score = 55.2 bits (127), Expect = 5e-07
Identities = 25/51 (49%), Positives = 37/51 (72%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK KP++E+ RR RIN L+E+K L++ +L + +K+EKADILE+TV
Sbjct: 24 RKTKKPLMEKLRRDRINNSLNEMKLLVLESLNKDVSRYSKMEKADILEMTV 74
>UniRef50_Q6P0J1 Cluster: Hairy and enhancer of split 6; n=3; Danio
rerio|Rep: Hairy and enhancer of split 6 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 226
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/99 (35%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
RK KP++E+KRRARIN L EL+ L+ ++ + K+E A++LE+TV
Sbjct: 20 RKTRKPLVEKKRRARINESLQELRLLL-----ADPDAQVKMENAEVLEMTVKRVESILQN 74
Query: 302 XXXXXNPSVD---VDRFRAGFTHAANEVSRCLASIPGVD 409
+ SV+ +RF AG+ +EV ++S PG+D
Sbjct: 75 KAKEAD-SVNREANERFAAGYIQCMHEVHTFVSSCPGID 112
>UniRef50_Q8AXV5 Cluster: Hairy/enhancer-of-split related with YRPW
motif-like protein; n=6; Clupeocephala|Rep:
Hairy/enhancer-of-split related with YRPW motif-like
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 310
Score = 54.8 bits (126), Expect = 6e-07
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 295
RK + ++E++RR RIN L EL+ L+ SA + +G +KLEKA+IL++TV
Sbjct: 44 RKKRRGIIEKRRRDRINHSLSELRRLVPSAFEKQGS--SKLEKAEILQMTVDHLKLLHAM 101
Query: 296 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
++ VD GF EV R L+S+ GV+
Sbjct: 102 GGKGYFDARALAVDYRTLGFRECVGEVVRYLSSLEGVE 139
>UniRef50_Q8UW74 Cluster: HES-related 1A; n=4; Xenopus|Rep:
HES-related 1A - Xenopus laevis (African clawed frog)
Length = 180
Score = 54.0 bits (124), Expect = 1e-06
Identities = 33/107 (30%), Positives = 55/107 (51%)
Frame = +2
Query: 89 GPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILEL 268
G V +RK++KP++E++RR RIN L++L+ + L+SE K+EKA+ILE
Sbjct: 3 GTSEVKPMETHRKLLKPLVEKRRRERINNSLEKLRIFLFQTLKSEKLKNPKVEKAEILEC 62
Query: 269 TVXXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
TV +VD + +++GF H + S P ++
Sbjct: 63 TV--QFLQSRKLLPLDREAVDKE-YQSGFQHCLETTLHFMNSKPDMN 106
>UniRef50_Q4S814 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 9
SCAF14710, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 182
Score = 53.6 bits (123), Expect = 1e-06
Identities = 25/50 (50%), Positives = 37/50 (74%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++ KP++E+ RR RIN C+D+LK ++ Q + N +KLEKADILE+TV
Sbjct: 49 QLRKPVVEKMRRDRINSCIDQLKVILEKEFQKQEPN-SKLEKADILEMTV 97
>UniRef50_Q4QRL6 Cluster: Hairy-related 12; n=2; Danio rerio|Rep:
Hairy-related 12 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 155
Score = 53.6 bits (123), Expect = 1e-06
Identities = 26/50 (52%), Positives = 35/50 (70%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ KP++E+ RR RIN C+D+LK L+ S + KLEKADILE+TV
Sbjct: 23 KLRKPIVEKMRRDRINTCIDQLKSLLEKEFHSHDPS-TKLEKADILEMTV 71
>UniRef50_A3KQ57 Cluster: Hairy and enhancer of split related-7;
n=3; Danio rerio|Rep: Hairy and enhancer of split
related-7 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 206
Score = 53.6 bits (123), Expect = 1e-06
Identities = 25/51 (49%), Positives = 36/51 (70%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK++KP +ER+RR R+NR L+ LK L++ + N +LEKA+ILE TV
Sbjct: 14 RKLLKPQVERRRRERMNRSLENLKLLLLQGPEHNQPNQRRLEKAEILEYTV 64
>UniRef50_A1L3K9 Cluster: LOC100037036 protein; n=2; Xenopus|Rep:
LOC100037036 protein - Xenopus laevis (African clawed
frog)
Length = 222
Score = 53.6 bits (123), Expect = 1e-06
Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 2/98 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
R+ KP++E++RRARIN L EL+ ++ S+ E K+E A++L+LTV
Sbjct: 41 RQTRKPLVEKRRRARINESLQELRGIL-----SDNEFQTKIENAEVLDLTVKRVERILRN 95
Query: 302 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+ +RF AG+ +EV ++S PG+D
Sbjct: 96 RTAEADRLQREASERFAAGYIQCMHEVHTFVSSCPGID 133
>UniRef50_Q6V6Y9 Cluster: Hairy H protein; n=2; Coelomata|Rep: Hairy
H protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 66
Score = 53.6 bits (123), Expect = 1e-06
Identities = 27/57 (47%), Positives = 41/57 (71%), Gaps = 2/57 (3%)
Frame = +2
Query: 104 SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE--GENVAKLEKADILEL 268
S +Q RK KP++E++RRARIN L+ELK L++ ++ + + +KLEKADILE+
Sbjct: 10 SSPHQGRKSSKPLMEKRRRARINSSLNELKNLILGTVKDDINAPHHSKLEKADILEI 66
>UniRef50_Q4H3E4 Cluster: Transcription factor protein; n=1; Ciona
intestinalis|Rep: Transcription factor protein - Ciona
intestinalis (Transparent sea squirt)
Length = 248
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/100 (34%), Positives = 53/100 (53%), Gaps = 5/100 (5%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
RK + ++E++RR RIN L EL+ ++ +A + G +KLEKA+IL+LTV
Sbjct: 29 RKKRRGVIEKRRRDRINNSLSELRRMIPAASEKHGS--SKLEKAEILQLTVEHLKTLQSA 86
Query: 302 XXXXXNPSVD-----VDRFRAGFTHAANEVSRCLASIPGV 406
P +D VD GF +EV+R + S+ G+
Sbjct: 87 ISKGYFPFMDVRTMAVDYHSFGFRECVSEVARYMISMDGI 126
>UniRef50_UPI0000D5710A Cluster: PREDICTED: similar to CG10446-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10446-PA - Tribolium castaneum
Length = 177
Score = 53.2 bits (122), Expect = 2e-06
Identities = 28/58 (48%), Positives = 41/58 (70%), Gaps = 8/58 (13%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMV--------SALQSEGENVAKLEKADILELTV 274
+V KP++E+KRRARIN L+ LK++++ S+ + G+ AKLEKADILE+TV
Sbjct: 47 RVRKPLMEKKRRARINDSLEALKQILLDSKTTLKESSGKKSGQRTAKLEKADILEMTV 104
>UniRef50_UPI00005846BD Cluster: PREDICTED: similar to Hey1 protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Hey1 protein - Strongylocentrotus purpuratus
Length = 317
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/103 (33%), Positives = 57/103 (55%), Gaps = 6/103 (5%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV-XXXXXXXX 298
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 27 RKKRRGIIEKRRRDRINNSLTELRRLVPAAFEKQGS--AKLEKAEILQMTVDHLKYLHAK 84
Query: 299 XXXXXXNP-----SVDVDRFRAGFTHAANEVSRCLASIPGVDV 412
+P + +D GF A+EV+R L ++ G+D+
Sbjct: 85 GIDGSFHPYGEAHAYAMDYRVLGFRECASEVARYLVTVEGMDI 127
>UniRef50_Q4RKD6 Cluster: Chromosome 21 SCAF15029, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 21
SCAF15029, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 374
Score = 53.2 bits (122), Expect = 2e-06
Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 2/94 (2%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXXXXXX 307
+ ++E++RR RIN CL EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 107 RQIIEKRRRDRINNCLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAAGGKG 164
Query: 308 XXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
++ +D GF E +R L+ I G+D
Sbjct: 165 YFDAHALAMDYRGLGFRECLAETARYLSIIEGLD 198
>UniRef50_Q9Y5J3 Cluster: Hairy/enhancer-of-split related with YRPW
motif protein 1; n=33; Eumetazoa|Rep:
Hairy/enhancer-of-split related with YRPW motif protein
1 - Homo sapiens (Human)
Length = 304
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 295
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 296 XXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
++ +D GF EV+R L+ I G+D
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLD 145
>UniRef50_Q96HZ4 Cluster: Transcription cofactor HES-6; n=18;
cellular organisms|Rep: Transcription cofactor HES-6 -
Homo sapiens (Human)
Length = 224
Score = 53.2 bits (122), Expect = 2e-06
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 301
RK KP++E+KRRARIN L EL+ L+ A E AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80
Query: 302 XXXXXN--PSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+ +RF AG+ +EV +++ +D
Sbjct: 81 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAID 118
>UniRef50_Q7Q509 Cluster: ENSANGP00000020858; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020858 - Anopheles gambiae
str. PEST
Length = 202
Score = 52.8 bits (121), Expect = 3e-06
Identities = 44/127 (34%), Positives = 64/127 (50%), Gaps = 31/127 (24%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE---GENVAK-------- 241
+PV R+ R+ KP++E++RRARIN CL+ELK L++ A++ + G VA+
Sbjct: 27 EPVKRSSDNRRSNKPIMEKRRRARINNCLNELKTLILDAMKKDSFSGSFVAQIALTIINV 86
Query: 242 -----------------LEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTH 361
LEKADILE+TV +PSV +++F+AGF
Sbjct: 87 SPLFLLSSTSQPARHSKLEKADILEMTVKHLENLQRQQTAMSQATDPSV-MNKFKAGFNE 145
Query: 362 AANEVSR 382
A EV R
Sbjct: 146 CAQEVGR 152
>UniRef50_Q9W7B6 Cluster: BHLH-WRPW transcription factor ESR-5; n=2;
Xenopus laevis|Rep: BHLH-WRPW transcription factor ESR-5
- Xenopus laevis (African clawed frog)
Length = 203
Score = 52.0 bits (119), Expect = 5e-06
Identities = 25/57 (43%), Positives = 39/57 (68%)
Frame = +2
Query: 104 SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
S T+ RK++KP++E++RR RINR L E++ L+ ++ K+EKA+ILEL V
Sbjct: 7 SDTFPSRKILKPVVEKQRRDRINRSLGEMRILLFQLTGNQKLQNPKMEKAEILELAV 63
>UniRef50_UPI00000181D8 Cluster: Homolog of Brachydanio rerio "Hairy
and enhancer of split 6.; n=1; Takifugu rubripes|Rep:
Homolog of Brachydanio rerio "Hairy and enhancer of
split 6. - Takifugu rubripes
Length = 186
Score = 51.2 bits (117), Expect = 8e-06
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXXXXXX 313
KP++E+KRRARIN+ L+EL+ L+ +E + +KLE A++L +TV
Sbjct: 4 KPLVEKKRRARINKSLEELRLLV-----AEPDLQSKLENAELLAMTVKRVENILQDPTPD 58
Query: 314 XNPS--VDVDRFRAGFTHAANEVSRCLASIPGVD 409
S +RF AG+ ++V +++ PGVD
Sbjct: 59 AEASSREACERFTAGYIQCMHDVHTFVSTCPGVD 92
>UniRef50_Q96HZ4-2 Cluster: Isoform 2 of Q96HZ4 ; n=2;
Catarrhini|Rep: Isoform 2 of Q96HZ4 - Homo sapiens
(Human)
Length = 219
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/51 (54%), Positives = 35/51 (68%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK KP++E+KRRARIN L EL+ L+ A E AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTV 71
>UniRef50_A3KQ56 Cluster: Hairy-related 1; n=3; Danio rerio|Rep:
Hairy-related 1 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 328
Score = 50.8 bits (116), Expect = 1e-05
Identities = 26/52 (50%), Positives = 41/52 (78%), Gaps = 1/52 (1%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMV-SALQSEGENVAKLEKADILELTV 274
++++KP++E+KRR RIN+ L+EL+ L++ + L S +N KLEKA+ILEL V
Sbjct: 13 KRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQN-PKLEKAEILELAV 63
>UniRef50_Q9BYE0 Cluster: Transcription factor HES-7; n=11;
Theria|Rep: Transcription factor HES-7 - Homo sapiens
(Human)
Length = 225
Score = 50.8 bits (116), Expect = 1e-05
Identities = 23/50 (46%), Positives = 36/50 (72%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K++KP++E++RR RINR L+EL+ L++ + + KLEKA+ILE V
Sbjct: 14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63
>UniRef50_UPI00015A7FE8 Cluster: hairy-related 1; n=3;
Euteleostomi|Rep: hairy-related 1 - Danio rerio
Length = 63
Score = 50.4 bits (115), Expect = 1e-05
Identities = 26/52 (50%), Positives = 41/52 (78%), Gaps = 1/52 (1%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMV-SALQSEGENVAKLEKADILELTV 274
++++KP++E+KRR RIN+ L+EL+ L++ + L S +N KLEKA+ILEL V
Sbjct: 13 QRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQN-PKLEKAEILELAV 63
>UniRef50_Q53U32 Cluster: Enhancer of split related protein 3/7b;
n=3; Xenopus|Rep: Enhancer of split related protein 3/7b
- Xenopus laevis (African clawed frog)
Length = 159
Score = 50.4 bits (115), Expect = 1e-05
Identities = 25/50 (50%), Positives = 36/50 (72%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ KP++E+ RR RIN +++LK L+ + + NV KLEKADILE+TV
Sbjct: 20 KLRKPVVEKMRRDRINSSIEQLKVLLENVFHQQEPNV-KLEKADILEMTV 68
>UniRef50_Q2TP33 Cluster: Her5; n=1; Oryzias latipes|Rep: Her5 -
Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 192
Score = 50.4 bits (115), Expect = 1e-05
Identities = 25/51 (49%), Positives = 35/51 (68%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
R++ KP++ER+RR RIN L+ L+ LMV Q+E K+EKA+ILE V
Sbjct: 16 RRMSKPLMERRRRERINHSLETLRLLMVKHTQNEKLKNPKVEKAEILESVV 66
>UniRef50_Q4W593 Cluster: ESR4; n=3; Xenopus|Rep: ESR4 - Xenopus
tropicalis (Western clawed frog) (Silurana tropicalis)
Length = 243
Score = 50.0 bits (114), Expect = 2e-05
Identities = 23/51 (45%), Positives = 36/51 (70%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+++MKP++E++RR RIN+ L+ L+ L++ A E K EKADIL+ TV
Sbjct: 25 KRLMKPVIEKRRRDRINQSLEHLRTLLLEATHDETLKNPKAEKADILKKTV 75
>UniRef50_O16853 Cluster: Lin-22; n=2; Caenorhabditis|Rep: Lin-22 -
Caenorhabditis elegans
Length = 173
Score = 50.0 bits (114), Expect = 2e-05
Identities = 22/47 (46%), Positives = 33/47 (70%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
KP++E+KRRARIN+ L +LK++++ +K EKADILE+ V
Sbjct: 26 KPLMEKKRRARINKSLSQLKQILIQDEHKNSIQHSKWEKADILEMAV 72
>UniRef50_Q9NQ87 Cluster: Hairy/enhancer-of-split related with YRPW
motif-like protein; n=13; Amniota|Rep:
Hairy/enhancer-of-split related with YRPW motif-like
protein - Homo sapiens (Human)
Length = 328
Score = 50.0 bits (114), Expect = 2e-05
Identities = 25/59 (42%), Positives = 40/59 (67%)
Frame = +2
Query: 98 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
P S Q RK + ++E++RR RIN L EL+ L+ +A + +G +KLEKA++L++TV
Sbjct: 36 PSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTV 92
>UniRef50_Q2TP34 Cluster: Her1-11; n=1; Oryzias latipes|Rep: Her1-11
- Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 269
Score = 49.2 bits (112), Expect = 3e-05
Identities = 22/51 (43%), Positives = 37/51 (72%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++++KP++E+KRR RIN+ L EL+ L+++ + KLEKA+IL+L V
Sbjct: 15 KRILKPVVEKKRRDRINQSLAELRSLLLNVTSDPRLHNPKLEKAEILDLAV 65
>UniRef50_A7SMU2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 481
Score = 48.4 bits (110), Expect = 6e-05
Identities = 25/45 (55%), Positives = 34/45 (75%)
Frame = +2
Query: 140 MLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++E++RR RIN CL EL +L+ SA Q+ + KLEKA+ILELTV
Sbjct: 52 VIEKRRRDRINSCLSELAQLIPSA-QNGKQGSGKLEKAEILELTV 95
>UniRef50_Q6QB00 Cluster: Her/Hey-like protein; n=2;
Clupeocephala|Rep: Her/Hey-like protein - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 270
Score = 48.0 bits (109), Expect = 7e-05
Identities = 25/49 (51%), Positives = 35/49 (71%)
Frame = +2
Query: 128 VMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
V ++E++RR RINRCL+EL + + AL +N KLEKA+ILE+TV
Sbjct: 62 VSHKVIEKRRRDRINRCLNELGKTVPMALAK--QNSGKLEKAEILEMTV 108
>UniRef50_Q5TYJ1 Cluster: ENSANGP00000029214; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000029214 - Anopheles gambiae
str. PEST
Length = 141
Score = 38.7 bits (86), Expect(2) = 1e-04
Identities = 15/30 (50%), Positives = 25/30 (83%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSE 223
KP++E+KRRARIN L++LK L++ A++ +
Sbjct: 4 KPIMEKKRRARINNYLNDLKSLLLDAMKKD 33
Score = 28.3 bits (60), Expect(2) = 1e-04
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Frame = +2
Query: 236 AKLEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGV 406
+KLEKADIL+LTV +P+V ++F G+ +E+ + S+ V
Sbjct: 67 SKLEKADILDLTVKHLQDVERRRLNVAMAVDPTVP-EKFANGYRECIDEIGKYFDSLGSV 125
Query: 407 D 409
D
Sbjct: 126 D 126
>UniRef50_UPI00015B47F2 Cluster: PREDICTED: similar to RT01017p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
RT01017p - Nasonia vitripennis
Length = 306
Score = 47.2 bits (107), Expect = 1e-04
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXXXX 292
RK + M+E+KRR RIN L EL+ L+ +A + + KLEKA+IL+LTV
Sbjct: 130 RKRRRGMIEKKRRDRINASLGELRRLVPAA--ARDPHSGKLEKAEILQLTVEHLRTLRNK 187
Query: 293 XXXXXXXXNPSVDVDRFRAGFTHAANEVSRCLASIPGVD 409
+ + +D G+ EV R L ++ G+D
Sbjct: 188 VLRDLGYDSTKLAMDYHAVGWGECVAEVGRYLVTMEGLD 226
>UniRef50_Q5D212 Cluster: Hairy and enhancer of split 5; n=10;
Tetrapoda|Rep: Hairy and enhancer of split 5 - Gallus
gallus (Chicken)
Length = 157
Score = 47.2 bits (107), Expect = 1e-04
Identities = 24/50 (48%), Positives = 35/50 (70%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++ KP++E+ RR RIN +++LK L+ Q N +KLEKADILE+TV
Sbjct: 18 RLRKPIVEKLRRDRINSSIEQLKLLLEKEFQRHQPN-SKLEKADILEMTV 66
>UniRef50_Q4S832 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 9 SCAF14710, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 89
Score = 46.8 bits (106), Expect = 2e-04
Identities = 20/32 (62%), Positives = 26/32 (81%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQS 220
KV KP++E+KRRARIN+CLD+LK L+ S S
Sbjct: 1 KVSKPLMEKKRRARINKCLDQLKSLLESYYSS 32
>UniRef50_A7S155 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 184
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/56 (48%), Positives = 38/56 (67%), Gaps = 6/56 (10%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENV------AKLEKADILELTV 274
K K +LER+RRARIN+ L ELK L++S+L + V +L+KA+IL+LTV
Sbjct: 15 KASKHILERQRRARINQSLAELKNLVLSSLYHDNPEVYMDKSRERLDKAEILDLTV 70
>UniRef50_Q6W4T8 Cluster: Her11; n=3; Danio rerio|Rep: Her11 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 274
Score = 46.4 bits (105), Expect = 2e-04
Identities = 23/58 (39%), Positives = 37/58 (63%)
Frame = +2
Query: 101 VSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+++T ++ +KP++E+KRR RIN LD L++L+ KLEKA+IL+L V
Sbjct: 9 MTKTEGIKRRLKPVIEKKRRDRINHNLDALRDLLFKNTADTRLQNPKLEKAEILDLAV 66
>UniRef50_Q504H7 Cluster: Her5 protein; n=3; Danio rerio|Rep: Her5
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 225
Score = 46.0 bits (104), Expect = 3e-04
Identities = 22/51 (43%), Positives = 35/51 (68%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
R+V KP++E++RR RIN+ L+ L+ L++ +E K+EKA+ILE V
Sbjct: 27 RRVPKPLMEKRRRDRINQSLETLRMLLLENTNNEKLKNPKVEKAEILESVV 77
>UniRef50_Q53U31 Cluster: Enhancer of split related protein 1b; n=1;
Xenopus laevis|Rep: Enhancer of split related protein 1b
- Xenopus laevis (African clawed frog)
Length = 154
Score = 45.6 bits (103), Expect = 4e-04
Identities = 24/50 (48%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ KP++E+ RR RIN +++LK L+ + NV KLEKADILE V
Sbjct: 18 KLRKPIVEKMRRDRINNSIEQLKLLLGKEFHEQEPNV-KLEKADILEKAV 66
>UniRef50_Q90Z13 Cluster: Enhancer of split related 2; n=2;
Xenopus|Rep: Enhancer of split related 2 - Xenopus
laevis (African clawed frog)
Length = 183
Score = 45.2 bits (102), Expect = 5e-04
Identities = 25/55 (45%), Positives = 35/55 (63%)
Frame = +2
Query: 110 TYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
T Q K+ KPM+E+ RR RIN +++L+ L+ Q + +K EKADILEL V
Sbjct: 40 TKQKTKIRKPMVEKMRRDRINSSINQLRNLLEQEFQLLQPD-SKPEKADILELAV 93
>UniRef50_Q9YI65 Cluster: Basic-helix-loop-helix transcription
factor hairy2b; n=2; Xenopus|Rep: Basic-helix-loop-helix
transcription factor hairy2b - Xenopus laevis (African
clawed frog)
Length = 274
Score = 43.2 bits (97), Expect = 0.002
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 3/73 (4%)
Frame = +2
Query: 200 MVSALQSEGENVAKLEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAAN 370
M+ + + +KLEKADILE+TV +PSV + ++RAGF N
Sbjct: 35 MIPCISPQSSRHSKLEKADILEMTVKHLRNLQRVQMTAALTSDPSV-LGKYRAGFNECTN 93
Query: 371 EVSRCLASIPGVD 409
EV+R L++ GV+
Sbjct: 94 EVTRFLSTCEGVN 106
>UniRef50_Q5TA89 Cluster: Transcription factor HES-5; n=11;
Amniota|Rep: Transcription factor HES-5 - Homo sapiens
(Human)
Length = 166
Score = 43.2 bits (97), Expect = 0.002
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++ KP++E+ RR RIN +++LK L+ N +KLEKADILE+ V
Sbjct: 18 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 66
>UniRef50_UPI0000360D97 Cluster: Transcription factor HES-5 (Hairy
and enhancer of split 5).; n=2; Takifugu rubripes|Rep:
Transcription factor HES-5 (Hairy and enhancer of split
5). - Takifugu rubripes
Length = 147
Score = 42.7 bits (96), Expect = 0.003
Identities = 20/50 (40%), Positives = 35/50 (70%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++ KP++E+ RR RIN +++LK L+ + + +K+EKAD+LE+TV
Sbjct: 9 QLRKPLVEKLRRERINSSIEQLKSLLGPEFFKQQPD-SKMEKADVLEMTV 57
>UniRef50_Q4V986 Cluster: Her4.2 protein; n=8; Danio rerio|Rep:
Her4.2 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 152
Score = 42.7 bits (96), Expect = 0.003
Identities = 21/50 (42%), Positives = 34/50 (68%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ KPM+E+ RR RIN +++LK L+ + + ++ EKADILE+T+
Sbjct: 19 KLRKPMVEKIRRERINSSIEKLKTLLAQEFVKQQPD-SRQEKADILEMTL 67
>UniRef50_Q9PTN9 Cluster: Enhancer of split related epidermal
protein-6; n=2; Xenopus|Rep: Enhancer of split related
epidermal protein-6 - Xenopus laevis (African clawed
frog)
Length = 144
Score = 42.3 bits (95), Expect = 0.004
Identities = 21/47 (44%), Positives = 33/47 (70%)
Frame = +2
Query: 134 KPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
KP++E+ RR RIN +++L+ L+ Q+ + +KLEKADILE+ V
Sbjct: 4 KPVIEKMRRDRINNSIEQLRILLERNFQTHHPH-SKLEKADILEMAV 49
>UniRef50_Q28JA3 Cluster: Novel helix-loop-helix DNA binding domain
protein; n=2; Xenopus tropicalis|Rep: Novel
helix-loop-helix DNA binding domain protein - Xenopus
tropicalis (Western clawed frog) (Silurana tropicalis)
Length = 155
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/51 (43%), Positives = 34/51 (66%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK+ KP++E+ RR RIN +++L+ L+ +S +K EKADILE+ V
Sbjct: 20 RKMRKPVVEKMRRDRINSSIEQLRMLLEKEFESH-HLPSKPEKADILEVAV 69
>UniRef50_Q1L7T5 Cluster: Her4; n=5; Percomorpha|Rep: Her4 - Oryzias
latipes (Medaka fish) (Japanese ricefish)
Length = 166
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ KPM+E+ RR RIN +++LK L+ + + +K EKADILE+ V
Sbjct: 19 KLRKPMVEKLRRDRINTSIEQLKSLLSPEFLRQQPD-SKQEKADILEMAV 67
>UniRef50_A6NFD8 Cluster: Uncharacterized protein ENSP00000343464;
n=10; Theria|Rep: Uncharacterized protein
ENSP00000343464 - Homo sapiens (Human)
Length = 327
Score = 36.3 bits (80), Expect(2) = 0.006
Identities = 16/34 (47%), Positives = 24/34 (70%)
Frame = +2
Query: 128 VMKPMLERKRRARINRCLDELKELMVSALQSEGE 229
V ++E++RR RINRCL+EL + + AL +GE
Sbjct: 57 VSHKVIEKRRRDRINRCLNELGKTVPMALAKQGE 90
Score = 24.6 bits (51), Expect(2) = 0.006
Identities = 14/21 (66%), Positives = 16/21 (76%)
Frame = +2
Query: 212 LQSEGENVAKLEKADILELTV 274
LQS G KLEKA+ILE+TV
Sbjct: 128 LQSSG----KLEKAEILEMTV 144
>UniRef50_Q688C9 Cluster: 213F14-1; n=9; Xenopus|Rep: 213F14-1 -
Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 158
Score = 41.5 bits (93), Expect = 0.006
Identities = 22/51 (43%), Positives = 33/51 (64%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK+ KP++E+ RR RIN +++L+ L+ S +K EKADILE+ V
Sbjct: 22 RKMRKPVVEKMRRDRINSSIEQLRMLLEKEFDSH-HLPSKPEKADILEVAV 71
>UniRef50_Q5TGS1 Cluster: Transcription factor HES-3; n=11;
Eutheria|Rep: Transcription factor HES-3 - Homo sapiens
(Human)
Length = 186
Score = 41.5 bits (93), Expect = 0.006
Identities = 24/44 (54%), Positives = 30/44 (68%)
Frame = +2
Query: 143 LERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+E+KRRARIN L++LK L+ S KLEKADILEL+V
Sbjct: 1 MEKKRRARINVSLEQLKSLL-EKHYSHQIRKRKLEKADILELSV 43
>UniRef50_Q90464 Cluster: HER-2 protein; n=1; Danio rerio|Rep: HER-2
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 108
Score = 40.7 bits (91), Expect = 0.011
Identities = 19/40 (47%), Positives = 31/40 (77%)
Frame = +2
Query: 155 RRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RR RIN+C+++LK L+ + +++ + +KLEKADILE+ V
Sbjct: 2 RRDRINKCIEQLKILLKTEIKA-SQPCSKLEKADILEMAV 40
>UniRef50_UPI0000D9CBA5 Cluster: PREDICTED: similar to basic
helix-loop-helix domain containing, class B, 3; n=2;
Eutheria|Rep: PREDICTED: similar to basic
helix-loop-helix domain containing, class B, 3 - Macaca
mulatta
Length = 353
Score = 40.3 bits (90), Expect = 0.015
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>UniRef50_Q6GNE9 Cluster: LOC443665 protein; n=4; Xenopus|Rep:
LOC443665 protein - Xenopus laevis (African clawed frog)
Length = 409
Score = 40.3 bits (90), Expect = 0.015
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 96 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 143
>UniRef50_Q2L4U4 Cluster: BHLH protein DEC1b; n=5; Euteleostomi|Rep:
BHLH protein DEC1b - Oryzias latipes (Medaka fish)
(Japanese ricefish)
Length = 428
Score = 40.3 bits (90), Expect = 0.015
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 48 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 95
>UniRef50_Q99PV5 Cluster: Class B basic helix-loop-helix protein 3;
n=10; Euteleostomi|Rep: Class B basic helix-loop-helix
protein 3 - Mus musculus (Mouse)
Length = 410
Score = 40.3 bits (90), Expect = 0.015
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>UniRef50_Q9C0J9 Cluster: Class B basic helix-loop-helix protein 3;
n=9; Tetrapoda|Rep: Class B basic helix-loop-helix
protein 3 - Homo sapiens (Human)
Length = 482
Score = 40.3 bits (90), Expect = 0.015
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>UniRef50_O14503 Cluster: Class B basic helix-loop-helix protein 2;
n=22; Euteleostomi|Rep: Class B basic helix-loop-helix
protein 2 - Homo sapiens (Human)
Length = 412
Score = 40.3 bits (90), Expect = 0.015
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +2
Query: 125 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 54 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101
>UniRef50_Q9VGZ5 Cluster: CG17100-PA; n=4; Sophophora|Rep:
CG17100-PA - Drosophila melanogaster (Fruit fly)
Length = 698
Score = 38.3 bits (85), Expect = 0.060
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 4/94 (4%)
Frame = +2
Query: 5 EGSAQTYTF-TEHTMSTMSYEIAYSLADDGPQPVSR---TYQYRKVMKPMLERKRRARIN 172
E + ++ + TE +++ + AYS DD R T + + ++E++RR R+N
Sbjct: 21 EAAVSSFPYCTESSLNFSTSATAYS-EDDAEYATGRRNKTSRQDPLSHRIIEKRRRDRMN 79
Query: 173 RCLDELKELMVSALQSEGENVAKLEKADILELTV 274
CL +L L+ Q +G ++EK +I+E+ +
Sbjct: 80 SCLADLSRLIPPQYQRKGR--GRIEKTEIIEMAI 111
>UniRef50_Q16SR7 Cluster: Class b basic helix-loop-helix protein;
n=2; Culicidae|Rep: Class b basic helix-loop-helix
protein - Aedes aegypti (Yellowfever mosquito)
Length = 507
Score = 38.3 bits (85), Expect = 0.060
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +2
Query: 5 EGSAQTYTFTEHTMSTMSYEIAYSL--ADDGPQPVSRTYQYRKVMKPMLERKRRARINRC 178
E S Y++ ++ + YS AD P +T + + ++E++RR R+N C
Sbjct: 3 EASVPGYSYCNEQLNFSTTNTNYSEDDADFAPGRRGKTSRQDPLSHRIIEKRRRDRMNSC 62
Query: 179 LDELKELMVSALQSEGENVAKLEKADILELTV 274
L +L L+ +G ++EK +I+E+ +
Sbjct: 63 LADLSRLIPQQYMRKGR--GRVEKTEIIEMAI 92
>UniRef50_Q1L7T8 Cluster: Her7; n=1; Oryzias latipes|Rep: Her7 -
Oryzias latipes (Medaka fish) (Japanese ricefish)
Length = 201
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/51 (37%), Positives = 34/51 (66%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RK++K +E++RR R+NR L+ L+ +++ + ++EKA+ILE TV
Sbjct: 14 RKLLKSQVEKRRRERMNRSLERLRTMLLPE-PHQVTPKHRVEKAEILEHTV 63
>UniRef50_A7RYX5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 211
Score = 37.5 bits (83), Expect = 0.11
Identities = 24/51 (47%), Positives = 32/51 (62%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
+K K ER+RR RIN+ L+ELK ++ L +NV KLE A ILE +V
Sbjct: 20 QKATKSYAERQRRTRINKSLEELK---LTVLGPSYQNV-KLEHAAILEFSV 66
>UniRef50_Q6XLP6 Cluster: Hairy-related 9; n=2; Clupeocephala|Rep:
Hairy-related 9 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 50
Score = 37.1 bits (82), Expect = 0.14
Identities = 16/36 (44%), Positives = 23/36 (63%)
Frame = +2
Query: 92 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKEL 199
P ++RK KP++E++RRARIN L +LK L
Sbjct: 15 PDKPKNASEHRKSSKPIMEKRRRARINESLGQLKTL 50
>UniRef50_Q5KHD0 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 641
Score = 37.1 bits (82), Expect = 0.14
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +2
Query: 116 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
Q RKV ++ER+RR +IN L+EL+ MV +L G + K ++LE TV
Sbjct: 130 QLRKVNHSLIERRRREKINAALNELRR-MVPSLGENGGKGGEF-KLEVLEKTV 180
>UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14556, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2646
Score = 36.7 bits (81), Expect = 0.18
Identities = 19/46 (41%), Positives = 25/46 (54%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 232
QP+ R +Y+ V+K ++ K R N CL E MVSAL EN
Sbjct: 2026 QPLERIQKYKVVLKELIRNKARNGQNCCLLEEAYAMVSALPQRSEN 2071
>UniRef50_Q693N2 Cluster: Hairy; n=1; Clogmia albipunctata|Rep:
Hairy - Clogmia albipunctata (Mothmidge)
Length = 316
Score = 36.7 bits (81), Expect = 0.18
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Frame = +2
Query: 236 AKLEKADILELTVXXXXXXXXXXXXXXNPSVD--VDRFRAGFTHAANEVSR 382
+KLEKADILE TV S +++F+AGFT ANEV R
Sbjct: 6 SKLEKADILEKTVKHLQDLQRQQSVLSQASDPGVINKFKAGFTECANEVGR 56
>UniRef50_Q2H624 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 413
Score = 36.3 bits (80), Expect = 0.24
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 80 ADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKAD 256
A G QP SRT + R V + ERKRR + D+L++LM S+ L KA+
Sbjct: 277 AHAGAQPYSRTPELR-VSHKLAERKRRTEMKELFDQLRDLMPQERGSKASKWEILTKAE 334
>UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin - Mus
musculus (Mouse)
Length = 8891
Score = 35.1 bits (77), Expect = 0.56
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 232
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 6771 QPVERVQKYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 6816
>UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin - Homo
sapiens (Human)
Length = 7968
Score = 35.1 bits (77), Expect = 0.56
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 232
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876
>UniRef50_Q5M8T3 Cluster: HES5 protein; n=3; Eutheria|Rep: HES5
protein - Homo sapiens (Human)
Length = 172
Score = 34.3 bits (75), Expect = 0.98
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +2
Query: 155 RRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
RR RIN +++LK L+ N +KLEKADILE+ V
Sbjct: 2 RRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 40
>UniRef50_Q6CD58 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
Similarity - Yarrowia lipolytica (Candida lipolytica)
Length = 493
Score = 34.3 bits (75), Expect = 0.98
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQS---EGENVAKLEKADILELTV 274
RK +ER+RR+++N D LK+L+ + QS EG + A L K IL+ TV
Sbjct: 294 RKTAHSAIERRRRSKMNEEFDSLKQLVPACRQSIAAEGGD-AGLHKLTILQATV 346
>UniRef50_UPI0000DB76C3 Cluster: PREDICTED: similar to CG17100-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG17100-PA - Apis mellifera
Length = 400
Score = 33.9 bits (74), Expect = 1.3
Identities = 14/45 (31%), Positives = 29/45 (64%)
Frame = +2
Query: 140 MLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
++E++RR R+N CL +L L+ + +G ++EK +I+E+ +
Sbjct: 73 IIEKRRRDRMNNCLADLSRLIPAEYLKKGR--GRVEKTEIIEMAI 115
>UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep:
LOC572412 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1095
Score = 33.9 bits (74), Expect = 1.3
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 232
+P R +YR ++K ++ K R N CL E MVS+L EN
Sbjct: 347 RPPERIQKYRALLKELIRNKARNGQNCCLLEQAYAMVSSLSQRSEN 392
>UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep:
MGC166429 protein - Bos taurus (Bovine)
Length = 813
Score = 33.9 bits (74), Expect = 1.3
Identities = 18/46 (39%), Positives = 24/46 (52%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 232
QPV R QY+ ++K ++ K R N L E +VSAL EN
Sbjct: 37 QPVERVQQYQALLKELIRNKARNGQNCALLEQAYAVVSALPQRAEN 82
>UniRef50_Q693M9 Cluster: Hairy; n=1; Coboldia fuscipes|Rep: Hairy -
Coboldia fuscipes
Length = 253
Score = 33.9 bits (74), Expect = 1.3
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Frame = +2
Query: 197 LMVSALQSEGENVAKLEKADILELTV---XXXXXXXXXXXXXXNPSVDVDRFRAGFTHAA 367
L++ A + + +KLEKADILE TV NP V +++F+AG+
Sbjct: 2 LILDATKKDPARHSKLEKADILEKTVKYLQDLQRQQSIISQAANPKV-LNKFKAGYMECV 60
Query: 368 NEVSR 382
N+V R
Sbjct: 61 NQVER 65
>UniRef50_Q4S869 Cluster: Chromosome 5 SCAF14709, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14709, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 492
Score = 33.5 bits (73), Expect = 1.7
Identities = 16/30 (53%), Positives = 17/30 (56%)
Frame = +1
Query: 271 SSSPSQTKAPTTLVTEPKCGRGSLPSWIHA 360
SSSP T LV P CGR +L SW HA
Sbjct: 441 SSSPEDRVLQTALVLLPLCGRDALLSWHHA 470
>UniRef50_A1SDB9 Cluster: Putative uncharacterized protein; n=1;
Nocardioides sp. JS614|Rep: Putative uncharacterized
protein - Nocardioides sp. (strain BAA-499 / JS614)
Length = 454
Score = 33.5 bits (73), Expect = 1.7
Identities = 19/55 (34%), Positives = 35/55 (63%), Gaps = 5/55 (9%)
Frame = +2
Query: 86 DGPQPVSRTYQ-YRKVMK--PMLERKRRARINRCL--DELKELMVSALQSEGENV 235
DGPQPVSR Y +++ P E++ A++ R + + L++++ +ALQS G+ +
Sbjct: 6 DGPQPVSRAESLYTALVRRNPETEQEMPAQVRRSIAPNGLRQVLANALQSSGDQL 60
>UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep:
Obscurin-MLCK - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 2009
Score = 33.1 bits (72), Expect = 2.3
Identities = 18/50 (36%), Positives = 27/50 (54%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKL 244
+P+ R Y+ V+K M+ K ++ N CL E MVS+L EN+ L
Sbjct: 134 RPMERIETYKTVLKEMIRNKAKSGQNCCLLEDAFAMVSSLPWRAENLHHL 183
>UniRef50_A7RQW2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 212
Score = 32.7 bits (71), Expect = 3.0
Identities = 18/57 (31%), Positives = 30/57 (52%)
Frame = +2
Query: 104 SRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 274
S + Q R+ + E+KRR I + D+L+ ++ + S KL KA IL+ T+
Sbjct: 37 SSSKQNRRFAHSVAEQKRRDAIKKGYDDLQSIVPTCQHSTSAGSPKLSKAIILQRTI 93
>UniRef50_UPI000155BBF4 Cluster: PREDICTED: similar to bHLH protein
Hesr-1/Hey1; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to bHLH protein Hesr-1/Hey1 -
Ornithorhynchus anatinus
Length = 320
Score = 32.3 bits (70), Expect = 4.0
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +2
Query: 122 RKVMKPMLERKRRARINRCLDELKELMVSALQSE 223
RK + ++E++RR RIN L EL+ L+ SA + +
Sbjct: 88 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQ 121
>UniRef50_Q4S9E3 Cluster: Chromosome undetermined SCAF14699, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14699,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 371
Score = 32.3 bits (70), Expect = 4.0
Identities = 14/25 (56%), Positives = 19/25 (76%)
Frame = +2
Query: 131 MKPMLERKRRARINRCLDELKELMV 205
+K +ER+RR RINR LD LK L++
Sbjct: 196 LKHHVERRRRERINRSLDSLKSLLL 220
>UniRef50_Q5BVU6 Cluster: SJCHGC09047 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09047 protein - Schistosoma
japonicum (Blood fluke)
Length = 332
Score = 32.3 bits (70), Expect = 4.0
Identities = 17/55 (30%), Positives = 30/55 (54%)
Frame = +2
Query: 98 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADIL 262
P+ + R++ K ER+RRA I+ ++ L L + + + N K+EK D+L
Sbjct: 70 PLEIREEVRRLKKRHTERQRRACISDKMNALHNLAMKLIGEDPSNHPKMEKNDVL 124
>UniRef50_Q13233 Cluster: Mitogen-activated protein kinase kinase
kinase 1; n=24; Euteleostomi|Rep: Mitogen-activated
protein kinase kinase kinase 1 - Homo sapiens (Human)
Length = 1514
Score = 31.5 bits (68), Expect = 6.9
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = -2
Query: 102 TGCGPSSASEYAIS*DIVDIVCSVKVYVCAEP 7
+G S +S+ +IS D+V+ CSV VCA+P
Sbjct: 615 SGGATSGSSQTSISGDVVEACCSVLSMVCADP 646
>UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio
"Obscurin-MLCK.; n=1; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Obscurin-MLCK. - Takifugu rubripes
Length = 1948
Score = 31.1 bits (67), Expect = 9.1
Identities = 15/47 (31%), Positives = 27/47 (57%)
Frame = +2
Query: 95 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENV 235
QPV R Y+ ++K +++ K ++ + CL E MVS+L +N+
Sbjct: 63 QPVERIQTYQALLKELIKNKAKSGQSCCLLEKSFSMVSSLPWRSDNL 109
>UniRef50_A6FPW1 Cluster: Serine/threonine protein phosphatase,
putative; n=1; Roseobacter sp. AzwK-3b|Rep:
Serine/threonine protein phosphatase, putative -
Roseobacter sp. AzwK-3b
Length = 308
Score = 31.1 bits (67), Expect = 9.1
Identities = 15/31 (48%), Positives = 22/31 (70%)
Frame = -1
Query: 139 RLHHFAILISARDGLRAVVRERIRDLVRHCR 47
+L H ILI+A DGL+A+ +RI +L+R R
Sbjct: 197 QLEHGDILIAASDGLQALGDDRIEELLRFTR 227
>UniRef50_A2FG49 Cluster: Adenylate and Guanylate cyclase catalytic
domain containing protein; n=4; Trichomonas vaginalis
G3|Rep: Adenylate and Guanylate cyclase catalytic domain
containing protein - Trichomonas vaginalis G3
Length = 1585
Score = 31.1 bits (67), Expect = 9.1
Identities = 14/44 (31%), Positives = 21/44 (47%)
Frame = +3
Query: 225 ERTLPNWRKLIFWN*QFVTFTN*GANDACH*TQVWTWIASELDS 356
+R W+K+ +W Q TF N H TQ++ +A L S
Sbjct: 77 QRATGTWKKIYYWALQICTFQNPNEYTVSHLTQLYICLAVSLTS 120
>UniRef50_Q4PGA2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1383
Score = 31.1 bits (67), Expect = 9.1
Identities = 19/58 (32%), Positives = 28/58 (48%)
Frame = +2
Query: 59 YEIAYSLADDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 232
Y+I+ SL DD P SR R ++ M +R RRA R + + K + + G N
Sbjct: 373 YDISLSLRDDANNPKSRK---RDRLRSMADRWRRATQGRTIMDRKSAAAATAAAAGSN 427
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 408,245,158
Number of Sequences: 1657284
Number of extensions: 7406143
Number of successful extensions: 23294
Number of sequences better than 10.0: 145
Number of HSP's better than 10.0 without gapping: 22538
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 23213
length of database: 575,637,011
effective HSP length: 92
effective length of database: 423,166,883
effective search space used: 18619342852
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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