Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0010_E15
(608 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 308 8e-84
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 308 8e-84
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 308 8e-84
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 308 8e-84
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 308 8e-84
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 308 8e-84
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 308 8e-84
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 308 8e-84
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 305 1e-82
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 304 1e-82
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 304 1e-82
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 304 1e-82
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 304 1e-82
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 304 1e-82
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 303 4e-82
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 215 8e-56
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 215 8e-56
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 215 8e-56
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 215 8e-56
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 215 8e-56
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 215 8e-56
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 215 8e-56
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 211 1e-54
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 211 1e-54
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 211 1e-54
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 211 1e-54
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 211 1e-54
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 208 9e-54
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 208 9e-54
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 208 9e-54
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 204 2e-52
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 204 2e-52
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 204 2e-52
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 204 2e-52
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 204 2e-52
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 204 2e-52
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 136 4e-32
AL135901-9|CAI40722.1| 90|Homo sapiens karyopherin alpha 3 (im... 110 3e-24
AL132795-7|CAI20502.1| 121|Homo sapiens karyopherin alpha 5 (im... 79 2e-14
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 55 2e-07
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 55 2e-07
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 55 2e-07
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 55 2e-07
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 55 2e-07
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 55 2e-07
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 54 4e-07
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 51 4e-06
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 51 4e-06
BC044907-1|AAH44907.1| 801|Homo sapiens ANKAR protein protein. 48 3e-05
AK126073-1|BAC86425.1| 1080|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AJ549812-1|CAD71147.1| 1363|Homo sapiens hypothetical protein pr... 48 3e-05
U51269-1|AAC51202.1| 962|Homo sapiens armadillo repeat protein ... 39 0.016
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 36 0.15
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 36 0.15
BC013424-1|AAH13424.1| 385|Homo sapiens armadillo repeat contai... 36 0.15
AK023749-1|BAB14666.1| 875|Homo sapiens protein ( Homo sapiens ... 35 0.26
AK001721-1|BAA91861.1| 443|Homo sapiens protein ( Homo sapiens ... 35 0.26
U31468-1|AAC03241.1| 347|Homo sapiens homeobox protein protein. 34 0.45
AB058756-1|BAB47482.1| 708|Homo sapiens KIAA1853 protein protein. 33 1.0
M60495-1|AAA63245.1| 200|Homo sapiens profilaggrin protein. 32 1.8
X88824-1|CAA61294.1| 127|Homo sapiens immunoglobulin V(H) gene ... 30 5.5
M94173-1|AAA51898.1| 2237|Homo sapiens N-type calcium channel al... 30 5.5
M94172-1|AAA51897.1| 2339|Homo sapiens N-type calcium channel al... 30 5.5
M68956-1|AAA59555.1| 332|Homo sapiens myristoylated alanine-ric... 30 5.5
DQ341274-1|ABC67467.1| 332|Homo sapiens myristoylated alanine-r... 30 5.5
BC089040-1|AAH89040.1| 332|Homo sapiens myristoylated alanine-r... 30 5.5
BC068059-1|AAH68059.1| 157|Homo sapiens MARCKS protein protein. 30 5.5
BC013004-1|AAH13004.1| 157|Homo sapiens MARCKS protein protein. 30 5.5
AL772363-4|CAI17142.1| 2337|Homo sapiens calcium channel, voltag... 30 5.5
AL772363-3|CAI17144.1| 2339|Homo sapiens calcium channel, voltag... 30 5.5
AL772363-2|CAI17143.1| 2338|Homo sapiens calcium channel, voltag... 30 5.5
AL772363-1|CAI17141.1| 2237|Homo sapiens calcium channel, voltag... 30 5.5
AL591424-4|CAI40688.1| 2337|Homo sapiens calcium channel, voltag... 30 5.5
AL591424-3|CAI40687.1| 2339|Homo sapiens calcium channel, voltag... 30 5.5
AL591424-2|CAI40686.1| 2338|Homo sapiens calcium channel, voltag... 30 5.5
AL591424-1|CAI40685.1| 2237|Homo sapiens calcium channel, voltag... 30 5.5
AL132660-2|CAI19942.1| 332|Homo sapiens myristoylated alanine-r... 30 5.5
AK123353-1|BAC85591.1| 195|Homo sapiens DC3) mRNA. protein. 30 7.3
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 29 9.7
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 29 9.7
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 29 9.7
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 29 9.7
BC002872-1|AAH02872.1| 339|Homo sapiens KIAA0515 protein protein. 29 9.7
AL358781-1|CAI40214.1| 1535|Homo sapiens KIAA0515 protein. 29 9.7
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 29 9.7
AB046765-1|BAB13371.2| 968|Homo sapiens KIAA1545 protein protein. 29 9.7
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.9 bits (176), Expect = 2e-13
Identities = 46/161 (28%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H +V + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.5 bits (170), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.7 bits (143), Expect = 2e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D +N+V+D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---VNIVVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 60.1 bits (139), Expect = 6e-09
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 308 bits (757), Expect = 8e-84
Identities = 143/198 (72%), Positives = 169/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 305 bits (748), Expect = 1e-82
Identities = 142/198 (71%), Positives = 168/198 (84%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHF LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAAWA+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQDVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 74.5 bits (175), Expect = 3e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAAWAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 59.7 bits (138), Expect = 8e-09
Identities = 42/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ ++ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 304 bits (747), Expect = 1e-82
Identities = 141/198 (71%), Positives = 170/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCDALSHFPALL+H KEKI KEAVWFLSNI
Sbjct: 54 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI 113
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDA L+P I+ L KG+F TQKEAAWA+SNL++SG K+QV LI VI
Sbjct: 114 TAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVI 173
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLL+ KD QV+ VVLDGLSN+LKMA + A+ + N+IEECGG+++IE LQ+HE +I
Sbjct: 174 PPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDI 233
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+AY+I +Q+F D+ D
Sbjct: 234 YKLAYEIIDQFFSSDDID 251
Score = 75.8 bits (178), Expect = 1e-13
Identities = 47/161 (29%), Positives = 83/161 (51%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H +V + + A+ + +EQ Q+V++ + H LLSHQ+ K+ A+ + NI
Sbjct: 13 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIV 72
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ L L + + KEA W +SN++ +G ++QV A+I+ ++P
Sbjct: 73 TGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDANLVP 131
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+LL D +SN L ++G DQVA +I++
Sbjct: 132 MIIHLLDKGDFGTQKEAAWAISN-LTISGRK-DQVAYLIQQ 170
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/121 (34%), Positives = 65/121 (53%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 10 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 69
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC + F LL+ ++ + LSN+ AG N QV +I
Sbjct: 70 NI-VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 125
Query: 490 E 492
+
Sbjct: 126 D 126
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 304 bits (747), Expect = 1e-82
Identities = 141/198 (71%), Positives = 170/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCDALSHFPALL+H KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDA L+P I+ L KG+F TQKEAAWA+SNL++SG K+QV LI VI
Sbjct: 354 TAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLL+ KD QV+ VVLDGLSN+LKMA + A+ + N+IEECGG+++IE LQ+HE +I
Sbjct: 414 PPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+AY+I +Q+F D+ D
Sbjct: 474 YKLAYEIIDQFFSSDDID 491
Score = 75.8 bits (178), Expect = 1e-13
Identities = 47/161 (29%), Positives = 83/161 (51%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H +V + + A+ + +EQ Q+V++ + H LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ L L + + KEA W +SN++ +G ++QV A+I+ ++P
Sbjct: 313 TGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDANLVP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+LL D +SN L ++G DQVA +I++
Sbjct: 372 MIIHLLDKGDFGTQKEAAWAISN-LTISGRK-DQVAYLIQQ 410
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/121 (34%), Positives = 65/121 (53%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC + F LL+ ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 63.7 bits (148), Expect = 5e-10
Identities = 44/175 (25%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT EQTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D +N+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQIQMVIDS-GIVPHLVPLLSHQEVKV 300
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 304 bits (747), Expect = 1e-82
Identities = 141/198 (71%), Positives = 170/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCDALSHFPALL+H KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDA L+P I+ L KG+F TQKEAAWA+SNL++SG K+QV LI VI
Sbjct: 354 TAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLL+ KD QV+ VVLDGLSN+LKMA + A+ + N+IEECGG+++IE LQ+HE +I
Sbjct: 414 PPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+AY+I +Q+F D+ D
Sbjct: 474 YKLAYEIIDQFFSSDDID 491
Score = 75.8 bits (178), Expect = 1e-13
Identities = 47/161 (29%), Positives = 83/161 (51%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H +V + + A+ + +EQ Q+V++ + H LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ L L + + KEA W +SN++ +G ++QV A+I+ ++P
Sbjct: 313 TGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDANLVP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+LL D +SN L ++G DQVA +I++
Sbjct: 372 MIIHLLDKGDFGTQKEAAWAISN-LTISGRK-DQVAYLIQQ 410
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/121 (34%), Positives = 65/121 (53%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC + F LL+ ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 63.7 bits (148), Expect = 5e-10
Identities = 44/175 (25%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT EQTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D +N+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQIQMVIDS-GIVPHLVPLLSHQEVKV 300
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 304 bits (747), Expect = 1e-82
Identities = 141/198 (71%), Positives = 170/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCDALSHFPALL+H KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDA L+P I+ L KG+F TQKEAAWA+SNL++SG K+QV LI VI
Sbjct: 354 TAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLL+ KD QV+ VVLDGLSN+LKMA + A+ + N+IEECGG+++IE LQ+HE +I
Sbjct: 414 PPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+AY+I +Q+F D+ D
Sbjct: 474 YKLAYEIIDQFFSSDDID 491
Score = 75.8 bits (178), Expect = 1e-13
Identities = 47/161 (29%), Positives = 83/161 (51%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H +V + + A+ + +EQ Q+V++ + H LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ L L + + KEA W +SN++ +G ++QV A+I+ ++P
Sbjct: 313 TGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDANLVP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+LL D +SN L ++G DQVA +I++
Sbjct: 372 MIIHLLDKGDFGTQKEAAWAISN-LTISGRK-DQVAYLIQQ 410
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/121 (34%), Positives = 65/121 (53%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC + F LL+ ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 63.7 bits (148), Expect = 5e-10
Identities = 44/175 (25%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT EQTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D +N+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQIQMVIDS-GIVPHLVPLLSHQEVKV 300
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 304 bits (747), Expect = 1e-82
Identities = 141/198 (71%), Positives = 170/198 (85%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCDALSHFPALL+H KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDA L+P I+ L KG+F TQKEAAWA+SNL++SG K+QV LI VI
Sbjct: 354 TAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLL+ KD QV+ VVLDGLSN+LKMA + A+ + N+IEECGG+++IE LQ+HE +I
Sbjct: 414 PPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+AY+I +Q+F D+ D
Sbjct: 474 YKLAYEIIDQFFSSDDID 491
Score = 75.8 bits (178), Expect = 1e-13
Identities = 47/161 (29%), Positives = 83/161 (51%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H +V + + A+ + +EQ Q+V++ + H LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ L L + + KEA W +SN++ +G ++QV A+I+ ++P
Sbjct: 313 TGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDANLVP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+LL D +SN L ++G DQVA +I++
Sbjct: 372 MIIHLLDKGDFGTQKEAAWAISN-LTISGRK-DQVAYLIQQ 410
Score = 65.7 bits (153), Expect = 1e-10
Identities = 42/121 (34%), Positives = 65/121 (53%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC + F LL+ ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 63.7 bits (148), Expect = 5e-10
Identities = 44/175 (25%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT EQTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D +N+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQIQMVIDS-GIVPHLVPLLSHQEVKV 300
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 303 bits (743), Expect = 4e-82
Identities = 142/198 (71%), Positives = 168/198 (84%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
SH+EVKVQTAALRA+GNIVTGTDEQTQVVLNCD LSHFP LLSH KEKI KEAVWFLSNI
Sbjct: 294 SHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI 353
Query: 190 TAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVI 369
TAGN+QQVQAVIDAGL+P I+ LAKG+F TQKEAA A+SNL++SG K+QV L+ VI
Sbjct: 354 TAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAARAISNLTISGRKDQVEYLVQQNVI 413
Query: 370 PPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
PPFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I
Sbjct: 414 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDI 473
Query: 550 FKMAYDIFEQYFGGDEED 603
+K+A++I +QYF GD+ D
Sbjct: 474 YKLAFEIIDQYFSGDDID 491
Score = 75.4 bits (177), Expect = 1e-13
Identities = 45/161 (27%), Positives = 85/161 (52%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H ++ + + A+ + G +EQ Q+V++ + LLSHQ+ K+ A+ + NI
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIV 312
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q V++ +L L+ + + KEA W +SN++ +G ++QV A+I+ G+IP
Sbjct: 313 TGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAGLIP 371
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
+ L+ D +SN L ++G DQV ++++
Sbjct: 372 MIIHQLAKGDFGTQKEAARAISN-LTISGRK-DQVEYLVQQ 410
Score = 72.1 bits (169), Expect = 1e-12
Identities = 46/121 (38%), Positives = 68/121 (56%)
Frame = +1
Query: 130 LLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVS 309
L+ H I + VW LS +T G +Q+Q VID+G++P +V L+ E + Q A AV
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 310 NLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANII 489
N+ V+GT EQ ++NC V+ F NLLS ++ + LSN+ AG N QV +I
Sbjct: 310 NI-VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNI--TAG-NQQQVQAVI 365
Query: 490 E 492
+
Sbjct: 366 D 366
Score = 61.3 bits (142), Expect = 3e-09
Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT QTQ V+ +A+ F LL + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 208 QVQAVIDAGLLPKIVENLAKG-EFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
VI G++ ++ ++ + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEI 549
L+ D IN+++D + + + +Q+ +I+ G + + L SH++V++
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQIQMVIDS-GVVPFLVPLLSHQEVKV 300
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 100/197 (50%), Positives = 147/197 (74%), Gaps = 2/197 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGE--NADQVANIIEECGGIDQIEALQSHEKVEIF 552
NLL+ KDT++I V+LD +SN+ + A + ++++ +IEECGG+D+IEALQ+HE ++
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVY 485
Query: 553 KMAYDIFEQYFGGDEED 603
K + + E+YF +EE+
Sbjct: 486 KASLSLIEKYFSVEEEE 502
Score = 72.9 bits (171), Expect = 8e-13
Identities = 49/196 (25%), Positives = 91/196 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDEE 600
+ D F E+
Sbjct: 438 LVILDAISNIFQAAEK 453
Score = 54.4 bits (125), Expect = 3e-07
Identities = 25/80 (31%), Positives = 43/80 (53%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q +AV+D G +P + LA ++A WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLSCKD 402
+I G + P LL+ D
Sbjct: 198 DLVIKYGAVDPLLALLAVPD 217
Score = 54.0 bits (124), Expect = 4e-07
Identities = 34/106 (32%), Positives = 60/106 (56%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+ V++ A+ F +LL+ I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 44.4 bits (100), Expect = 3e-04
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTK 333
T+G +Q+ ++ G++ ++ L + + A+SN+ + K
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEK 453
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 100/197 (50%), Positives = 147/197 (74%), Gaps = 2/197 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGE--NADQVANIIEECGGIDQIEALQSHEKVEIF 552
NLL+ KDT++I V+LD +SN+ + A + ++++ +IEECGG+D+IEALQ+HE ++
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVY 485
Query: 553 KMAYDIFEQYFGGDEED 603
K + + E+YF +EE+
Sbjct: 486 KASLSLIEKYFSVEEEE 502
Score = 72.9 bits (171), Expect = 8e-13
Identities = 49/196 (25%), Positives = 91/196 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDEE 600
+ D F E+
Sbjct: 438 LVILDAISNIFQAAEK 453
Score = 54.4 bits (125), Expect = 3e-07
Identities = 25/80 (31%), Positives = 43/80 (53%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q +AV+D G +P + LA ++A WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLSCKD 402
+I G + P LL+ D
Sbjct: 198 DLVIKYGAVDPLLALLAVPD 217
Score = 54.0 bits (124), Expect = 4e-07
Identities = 34/106 (32%), Positives = 60/106 (56%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+ V++ A+ F +LL+ I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 44.4 bits (100), Expect = 3e-04
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTK 333
T+G +Q+ ++ G++ ++ L + + A+SN+ + K
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEK 453
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 102/198 (51%), Positives = 148/198 (74%), Gaps = 3/198 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGEN---ADQVANIIEECGGIDQIEALQSHEKVEI 549
NLL+ KDT++I V+LD +SN+ + A EN ++++ +IEECGG+D+IEALQ+HE +
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQ-AAENLGETEKLSIMIEECGGLDKIEALQNHENESV 484
Query: 550 FKMAYDIFEQYFGGDEED 603
+K + + E+YF +EE+
Sbjct: 485 YKASLSLIEKYFSVEEEE 502
Score = 72.5 bits (170), Expect = 1e-12
Identities = 49/195 (25%), Positives = 90/195 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDE 597
+ D F E
Sbjct: 438 LVILDAISNIFQAAE 452
Score = 52.8 bits (121), Expect = 9e-07
Identities = 24/80 (30%), Positives = 42/80 (52%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q + V+D G +P + LA ++A WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLSCKD 402
+I G + P LL+ D
Sbjct: 198 DLVIKYGAVDPLLALLAVPD 217
Score = 52.4 bits (120), Expect = 1e-06
Identities = 33/106 (31%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ +++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKVVVDGGAIPAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 48.0 bits (109), Expect = 3e-05
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+VV++ A+ F +LL+ I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/168 (23%), Positives = 76/168 (45%), Gaps = 6/168 (3%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVS----GTKEQVGALI 354
T+G +Q+ ++ G++ ++ L + + A+SN+ + G E++ +I
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAENLGETEKLSIMI 464
Query: 355 -NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
CG + L + ++ V L + + E DQ N++ E
Sbjct: 465 EECGGLDKIEALQNHENESVYKASLSLIEKYFSVE-EEEDQ--NVVPE 509
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 100/197 (50%), Positives = 147/197 (74%), Gaps = 2/197 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGE--NADQVANIIEECGGIDQIEALQSHEKVEIF 552
NLL+ KDT++I V+LD +SN+ + A + ++++ +IEECGG+D+IEALQ+HE ++
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVY 485
Query: 553 KMAYDIFEQYFGGDEED 603
K + + E+YF +EE+
Sbjct: 486 KASLSLIEKYFSVEEEE 502
Score = 72.9 bits (171), Expect = 8e-13
Identities = 49/196 (25%), Positives = 91/196 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDEE 600
+ D F E+
Sbjct: 438 LVILDAISNIFQAAEK 453
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/106 (31%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQ-TQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ A+++ G I F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIRAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQDVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/80 (28%), Positives = 41/80 (51%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q +AV+D G + + LA ++ WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLSCKD 402
+I G + P LL+ D
Sbjct: 198 DLVIKYGAVDPLLALLAVPD 217
Score = 44.4 bits (100), Expect = 3e-04
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTK 333
T+G +Q+ ++ G++ ++ L + + A+SN+ + K
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEK 453
Score = 44.0 bits (99), Expect = 4e-04
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+ V++ A+ F +LL+ I ++ VW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 100/197 (50%), Positives = 147/197 (74%), Gaps = 2/197 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGE--NADQVANIIEECGGIDQIEALQSHEKVEIF 552
NLL+ KDT++I V+LD +SN+ + A + ++++ +IEECGG+D+IEALQ+HE ++
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVY 485
Query: 553 KMAYDIFEQYFGGDEED 603
K + + E+YF +EE+
Sbjct: 486 KASLSLIEKYFSVEEEE 502
Score = 72.9 bits (171), Expect = 8e-13
Identities = 49/196 (25%), Positives = 91/196 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDEE 600
+ D F E+
Sbjct: 438 LVILDAISNIFQAAEK 453
Score = 54.0 bits (124), Expect = 4e-07
Identities = 34/106 (32%), Positives = 60/106 (56%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 52.8 bits (121), Expect = 9e-07
Identities = 24/77 (31%), Positives = 42/77 (54%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q +AV+D G +P + LA ++A WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLS 393
+I G + P LL+
Sbjct: 198 DLVIKYGAVDPLLALLA 214
Score = 47.6 bits (108), Expect = 3e-05
Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+ V++ A+ F +LL+ I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA E + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPEMSSLACGYLRNLTWTLSNL 236
Score = 44.4 bits (100), Expect = 3e-04
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTK 333
T+G +Q+ ++ G++ ++ L + + A+SN+ + K
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEK 453
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 102/198 (51%), Positives = 148/198 (74%), Gaps = 3/198 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGEN---ADQVANIIEECGGIDQIEALQSHEKVEI 549
NLL+ KDT++I V+LD +SN+ + A EN ++++ +IEECGG+D+IEALQ+HE +
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQ-AAENLGETEKLSIMIEECGGLDKIEALQNHENESV 484
Query: 550 FKMAYDIFEQYFGGDEED 603
+K + + E+YF +EE+
Sbjct: 485 YKASLSLIEKYFSVEEEE 502
Score = 72.5 bits (170), Expect = 1e-12
Identities = 49/195 (25%), Positives = 90/195 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDE 597
+ D F E
Sbjct: 438 LVILDAISNIFQAAE 452
Score = 52.8 bits (121), Expect = 9e-07
Identities = 24/80 (30%), Positives = 42/80 (52%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q + V+D G +P + LA ++A WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLSCKD 402
+I G + P LL+ D
Sbjct: 198 DLVIKYGAVDPLLALLAVPD 217
Score = 52.4 bits (120), Expect = 1e-06
Identities = 33/106 (31%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ +++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKVVVDGGAIPAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 48.0 bits (109), Expect = 3e-05
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+VV++ A+ F +LL+ I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 44.4 bits (100), Expect = 3e-04
Identities = 39/168 (23%), Positives = 76/168 (45%), Gaps = 6/168 (3%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVS----GTKEQVGALI 354
T+G +Q+ ++ G++ ++ L + + A+SN+ + G E++ +I
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAENLGETEKLSIMI 464
Query: 355 -NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEE 495
CG + L + ++ V L + + E DQ N++ E
Sbjct: 465 EECGGLDKIEALQNHENESVYKASLSLIEKYFSVE-EEEDQ--NVVPE 509
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 215 bits (526), Expect = 8e-56
Identities = 100/197 (50%), Positives = 147/197 (74%), Gaps = 2/197 (1%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
E+ + T ALRAIGNIVTGTDEQTQVV++ AL+ FP+LL++ K I KEA W +SNITAG
Sbjct: 306 ELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAG 365
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q+Q V++ GL+P +V L+K +F+TQKEA WAV+N + GT EQ+ L++CG+I P
Sbjct: 366 RQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPL 425
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGE--NADQVANIIEECGGIDQIEALQSHEKVEIF 552
NLL+ KDT++I V+LD +SN+ + A + ++++ +IEECGG+D+IEALQ+HE ++
Sbjct: 426 MNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHENESVY 485
Query: 553 KMAYDIFEQYFGGDEED 603
K + + E+YF +EE+
Sbjct: 486 KASLSLIEKYFSVEEEE 502
Score = 72.9 bits (171), Expect = 8e-13
Identities = 49/196 (25%), Positives = 91/196 (46%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + +V AI + G +E+ +V+ + LL + I A+ + NI
Sbjct: 262 HDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV 321
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
G +Q Q VIDAG L L + QKEA W +SN++ +G ++Q+ ++N G++P
Sbjct: 322 TGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVNHGLVP 380
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
++LS D + + ++N +G +Q+ ++ CG I+ + L + + +I
Sbjct: 381 FLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAKDTKII 437
Query: 553 KMAYDIFEQYFGGDEE 600
+ D F E+
Sbjct: 438 LVILDAISNIFQAAEK 453
Score = 54.4 bits (125), Expect = 3e-07
Identities = 25/80 (31%), Positives = 43/80 (53%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +G +Q +AV+D G +P + LA ++A WA+ N++ G+ +
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFR- 197
Query: 343 GALINCGVIPPFCNLLSCKD 402
+I G + P LL+ D
Sbjct: 198 DLVIKYGAVDPLLALLAVPD 217
Score = 54.0 bits (124), Expect = 4e-07
Identities = 34/106 (32%), Positives = 60/106 (56%), Gaps = 1/106 (0%)
Frame = +1
Query: 211 VQAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
+ +I AGL+PK V L + + Q E+AWA++N++ SGT EQ A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEAL 525
L+ + + L N +AG+ + +++ + G +D + AL
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPLLAL 212
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q + A+ NI +GT EQT+ V++ A+ F +LL+ I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQT-----QKEAAWAVSNL 315
VI G + ++ LA + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 44.4 bits (100), Expect = 3e-04
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
++ + +Q A + NI G +Q Q V+N + ++LS K KEAVW ++N
Sbjct: 345 TNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNY 404
Query: 190 TAGNK-QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTK 333
T+G +Q+ ++ G++ ++ L + + A+SN+ + K
Sbjct: 405 TSGGTVEQIVYLVHCGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEK 453
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 211 bits (516), Expect = 1e-54
Identities = 102/205 (49%), Positives = 141/205 (68%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 305 HNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 364
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L++ G I
Sbjct: 365 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIK 424
Query: 373 PFCNLLSCKDTQVINVVLDGLSNML-------KMAGENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L K +G + +IEE G+D+IE LQS
Sbjct: 425 PLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQS 484
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG +++D+
Sbjct: 485 HENQEIYQKAFDLIEHYFGVEDDDS 509
Score = 62.5 bits (145), Expect = 1e-09
Identities = 51/187 (27%), Positives = 84/187 (44%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + + L LL + +A W LS ++ G +++QA
Sbjct: 230 AVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQA 289
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 290 VIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 348
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 349 KESIRKEACWTISNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 580 YFGGDEE 600
GG E
Sbjct: 406 TSGGTPE 412
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VLNC L+ LL+ + + AVW LSN+ G
Sbjct: 183 VQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKN 242
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + LP + L + +A WA+S LS G E++ A+I+ GV
Sbjct: 243 PPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVE 301
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V + L + N+ + G+ D +I C + + L S K I K A
Sbjct: 302 LLMHNDYKVASPALRAVGNI--VTGD--DIQTQVILNCSALPCLLHLLSSPKESIRKEA 356
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G QQ + VI+AG +P +E L Q++A WA+ N++ + +
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCR- 202
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 450
++NC ++ P LL S + T N V LSN+ +
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT +QT++V+ A+ F LL+ E + ++AVW L NI +
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQTQ-KEAAWAVSNL 315
V++ +L ++ L K T + A WA+SNL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 347 SPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G EQ G GV
Sbjct: 406 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLG--EQEGKRSGSGV 463
Query: 367 IPPFCNLL 390
P+C L+
Sbjct: 464 -NPYCGLI 470
Score = 41.1 bits (92), Expect = 0.003
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 LLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQV 411
++ + VE L + E T Q EAAWA++N++ SGT +Q +I G +P F LL+ V
Sbjct: 125 VVDRFVEFLKRNENCTLQFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDV 183
Query: 412 INVVLDGLSNMLKMAGENADQVAN 483
+ L N+ + D V N
Sbjct: 184 QEQAVWALGNIAGDSSVCRDYVLN 207
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 211 bits (516), Expect = 1e-54
Identities = 102/205 (49%), Positives = 141/205 (68%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 305 HNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 364
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L++ G I
Sbjct: 365 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIK 424
Query: 373 PFCNLLSCKDTQVINVVLDGLSNML-------KMAGENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L K +G + +IEE G+D+IE LQS
Sbjct: 425 PLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQS 484
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG +++D+
Sbjct: 485 HENQEIYQKAFDLIEHYFGVEDDDS 509
Score = 62.5 bits (145), Expect = 1e-09
Identities = 51/187 (27%), Positives = 84/187 (44%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + + L LL + +A W LS ++ G +++QA
Sbjct: 230 AVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQA 289
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 290 VIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 348
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 349 KESIRKEACWTISNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 580 YFGGDEE 600
GG E
Sbjct: 406 TSGGTPE 412
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VLNC L+ LL+ + + AVW LSN+ G
Sbjct: 183 VQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKN 242
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + LP + L + +A WA+S LS G E++ A+I+ GV
Sbjct: 243 PPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVE 301
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V + L + N+ + G+ D +I C + + L S K I K A
Sbjct: 302 LLMHNDYKVASPALRAVGNI--VTGD--DIQTQVILNCSALPCLLHLLSSPKESIRKEA 356
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G QQ + VI+AG +P +E L Q++A WA+ N++ + +
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCR- 202
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 450
++NC ++ P LL S + T N V LSN+ +
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT +QT++V+ A+ F LL+ E + ++AVW L NI +
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQTQ-KEAAWAVSNL 315
V++ +L ++ L K T + A WA+SNL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 347 SPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G EQ G GV
Sbjct: 406 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLG--EQEGKRSGSGV 463
Query: 367 IPPFCNLL 390
P+C L+
Sbjct: 464 -NPYCGLI 470
Score = 41.1 bits (92), Expect = 0.003
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 LLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQV 411
++ + VE L + E T Q EAAWA++N++ SGT +Q +I G +P F LL+ V
Sbjct: 125 VVDRFVEFLKRNENCTLQFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDV 183
Query: 412 INVVLDGLSNMLKMAGENADQVAN 483
+ L N+ + D V N
Sbjct: 184 QEQAVWALGNIAGDSSVCRDYVLN 207
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 211 bits (516), Expect = 1e-54
Identities = 102/205 (49%), Positives = 141/205 (68%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 305 HNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 364
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L++ G I
Sbjct: 365 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIK 424
Query: 373 PFCNLLSCKDTQVINVVLDGLSNML-------KMAGENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L K +G + +IEE G+D+IE LQS
Sbjct: 425 PLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQS 484
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG +++D+
Sbjct: 485 HENQEIYQKAFDLIEHYFGVEDDDS 509
Score = 62.5 bits (145), Expect = 1e-09
Identities = 51/187 (27%), Positives = 84/187 (44%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + + L LL + +A W LS ++ G +++QA
Sbjct: 230 AVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQA 289
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 290 VIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 348
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 349 KESIRKEACWTISNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 580 YFGGDEE 600
GG E
Sbjct: 406 TSGGTPE 412
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VLNC L+ LL+ + + AVW LSN+ G
Sbjct: 183 VQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKN 242
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + LP + L + +A WA+S LS G E++ A+I+ GV
Sbjct: 243 PPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVE 301
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V + L + N+ + G+ D +I C + + L S K I K A
Sbjct: 302 LLMHNDYKVASPALRAVGNI--VTGD--DIQTQVILNCSALPCLLHLLSSPKESIRKEA 356
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G QQ + VI+AG +P +E L Q++A WA+ N++ + +
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCR- 202
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 450
++NC ++ P LL S + T N V LSN+ +
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT +QT++V+ A+ F LL+ E + ++AVW L NI +
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQTQ-KEAAWAVSNL 315
V++ +L ++ L K T + A WA+SNL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 347 SPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G EQ G GV
Sbjct: 406 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLG--EQEGKRSGSGV 463
Query: 367 IPPFCNLL 390
P+C L+
Sbjct: 464 -NPYCGLI 470
Score = 41.1 bits (92), Expect = 0.003
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 LLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQV 411
++ + VE L + E T Q EAAWA++N++ SGT +Q +I G +P F LL+ V
Sbjct: 125 VVDRFVEFLKRNENCTLQFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDV 183
Query: 412 INVVLDGLSNMLKMAGENADQVAN 483
+ L N+ + D V N
Sbjct: 184 QEQAVWALGNIAGDSSVCRDYVLN 207
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 211 bits (516), Expect = 1e-54
Identities = 102/205 (49%), Positives = 141/205 (68%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 305 HNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 364
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L++ G I
Sbjct: 365 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIK 424
Query: 373 PFCNLLSCKDTQVINVVLDGLSNML-------KMAGENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L K +G + +IEE G+D+IE LQS
Sbjct: 425 PLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQS 484
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG +++D+
Sbjct: 485 HENQEIYQKAFDLIEHYFGVEDDDS 509
Score = 62.5 bits (145), Expect = 1e-09
Identities = 51/187 (27%), Positives = 84/187 (44%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + + L LL + +A W LS ++ G +++QA
Sbjct: 230 AVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQA 289
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 290 VIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 348
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 349 KESIRKEACWTISNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 580 YFGGDEE 600
GG E
Sbjct: 406 TSGGTPE 412
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VLNC L+ LL+ + + AVW LSN+ G
Sbjct: 183 VQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKN 242
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + LP + L + +A WA+S LS G E++ A+I+ GV
Sbjct: 243 PPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVE 301
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V + L + N+ + G+ D +I C + + L S K I K A
Sbjct: 302 LLMHNDYKVASPALRAVGNI--VTGD--DIQTQVILNCSALPCLLHLLSSPKESIRKEA 356
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G QQ + VI+AG +P +E L Q++A WA+ N++ + +
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCR- 202
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 450
++NC ++ P LL S + T N V LSN+ +
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT +QT++V+ A+ F LL+ E + ++AVW L NI +
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQTQ-KEAAWAVSNL 315
V++ +L ++ L K T + A WA+SNL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 347 SPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G EQ G GV
Sbjct: 406 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLG--EQEGKRSGSGV 463
Query: 367 IPPFCNLL 390
P+C L+
Sbjct: 464 -NPYCGLI 470
Score = 41.1 bits (92), Expect = 0.003
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 LLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQV 411
++ + VE L + E T Q EAAWA++N++ SGT +Q +I G +P F LL+ V
Sbjct: 125 VVDRFVEFLKRNENCTLQFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDV 183
Query: 412 INVVLDGLSNMLKMAGENADQVAN 483
+ L N+ + D V N
Sbjct: 184 QEQAVWALGNIAGDSSVCRDYVLN 207
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 211 bits (516), Expect = 1e-54
Identities = 102/205 (49%), Positives = 141/205 (68%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 305 HNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 364
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L++ G I
Sbjct: 365 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIK 424
Query: 373 PFCNLLSCKDTQVINVVLDGLSNML-------KMAGENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L K +G + +IEE G+D+IE LQS
Sbjct: 425 PLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQS 484
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG +++D+
Sbjct: 485 HENQEIYQKAFDLIEHYFGVEDDDS 509
Score = 62.5 bits (145), Expect = 1e-09
Identities = 51/187 (27%), Positives = 84/187 (44%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + + L LL + +A W LS ++ G +++QA
Sbjct: 230 AVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQA 289
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 290 VIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 348
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 349 KESIRKEACWTISNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 580 YFGGDEE 600
GG E
Sbjct: 406 TSGGTPE 412
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VLNC L+ LL+ + + AVW LSN+ G
Sbjct: 183 VQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKN 242
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + LP + L + +A WA+S LS G E++ A+I+ GV
Sbjct: 243 PPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVE 301
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V + L + N+ + G+ D +I C + + L S K I K A
Sbjct: 302 LLMHNDYKVASPALRAVGNI--VTGD--DIQTQVILNCSALPCLLHLLSSPKESIRKEA 356
Score = 56.0 bits (129), Expect = 1e-07
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G QQ + VI+AG +P +E L Q++A WA+ N++ + +
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCR- 202
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 450
++NC ++ P LL S + T N V LSN+ +
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/97 (32%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT +QT++V+ A+ F LL+ E + ++AVW L NI +
Sbjct: 141 LQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQTQ-KEAAWAVSNL 315
V++ +L ++ L K T + A WA+SNL
Sbjct: 201 CRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 347 SPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G EQ G GV
Sbjct: 406 TSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLG--EQEGKRSGSGV 463
Query: 367 IPPFCNLL 390
P+C L+
Sbjct: 464 -NPYCGLI 470
Score = 41.1 bits (92), Expect = 0.003
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +1
Query: 235 LLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCKDTQV 411
++ + VE L + E T Q EAAWA++N++ SGT +Q +I G +P F LL+ V
Sbjct: 125 VVDRFVEFLKRNENCTLQFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDV 183
Query: 412 INVVLDGLSNMLKMAGENADQVAN 483
+ L N+ + D V N
Sbjct: 184 QEQAVWALGNIAGDSSVCRDYVLN 207
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 208 bits (509), Expect = 9e-54
Identities = 102/204 (50%), Positives = 140/204 (68%), Gaps = 7/204 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 308 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNIT 367
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L+ G I
Sbjct: 368 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIK 427
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQ-------VANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ + + Q +IEE G+D+IE LQS
Sbjct: 428 PLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQS 487
Query: 532 HEKVEIFKMAYDIFEQYFGGDEED 603
HE EI++ A+D+ E YFG +E+D
Sbjct: 488 HENQEIYQKAFDLIEHYFGVEEDD 511
Score = 60.5 bits (140), Expect = 5e-09
Identities = 30/114 (26%), Positives = 58/114 (50%)
Frame = +1
Query: 49 AIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVID 228
A+ + G +++ Q V++ LL H K+ A+ + NI G+ Q Q +++
Sbjct: 278 ALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN 337
Query: 229 AGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
LP ++ L+ + +KEA W VSN++ +G + Q+ A+I+ + P +L
Sbjct: 338 CSALPCLLHLLSSPKESIRKEACWTVSNIT-AGNRAQIQAVIDANIFPVLIEIL 390
Score = 60.1 bits (139), Expect = 6e-09
Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT T+VV+ A+ F LL+ + E + ++AVW L NI N +
Sbjct: 144 LQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAE 203
Query: 208 QVQAVIDAGLLPKIVENLA-KGEFQTQKEAAWAVSNL 315
V++ +LP ++E L T + A WA+SNL
Sbjct: 204 CRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 240
Score = 58.4 bits (135), Expect = 2e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + + W LS ++ G ++QA
Sbjct: 233 AVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQA 292
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 293 VIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 351
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 352 KESIRKEACWTVSNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 408
Query: 580 YFGGDEE 600
GG E
Sbjct: 409 TSGGTPE 415
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G + VI+ G +P ++ L Q++A WA+ N++ E
Sbjct: 147 EAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIA-GDNAECR 205
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLKMAGENADQVANIIEEC 498
++NC ++PP LL S + T N V LSN+ + G+N + + C
Sbjct: 206 DFVLNCEILPPLLELLTNSNRLTTTRNAVW-ALSNLCR--GKNPPPNFSKVSPC 256
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Frame = +1
Query: 214 QAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
Q + G++ + V+ L + E T Q EAAWA++N++ SGT +I G +P F LL
Sbjct: 121 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIA-SGTFLHTKVVIETGAVPIFIKLL 179
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENAD 471
+ + V + L N +AG+NA+
Sbjct: 180 NSEHEDVQEQAVWALGN---IAGDNAE 203
Score = 38.3 bits (85), Expect = 0.021
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A + NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 350 SPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 408
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G +E I
Sbjct: 409 TSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIG--- 465
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 466 INPYCALI 473
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 208 bits (509), Expect = 9e-54
Identities = 102/204 (50%), Positives = 140/204 (68%), Gaps = 7/204 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 308 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNIT 367
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L+ G I
Sbjct: 368 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIK 427
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQ-------VANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ + + Q +IEE G+D+IE LQS
Sbjct: 428 PLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQS 487
Query: 532 HEKVEIFKMAYDIFEQYFGGDEED 603
HE EI++ A+D+ E YFG +E+D
Sbjct: 488 HENQEIYQKAFDLIEHYFGVEEDD 511
Score = 60.5 bits (140), Expect = 5e-09
Identities = 30/114 (26%), Positives = 58/114 (50%)
Frame = +1
Query: 49 AIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVID 228
A+ + G +++ Q V++ LL H K+ A+ + NI G+ Q Q +++
Sbjct: 278 ALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN 337
Query: 229 AGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
LP ++ L+ + +KEA W VSN++ +G + Q+ A+I+ + P +L
Sbjct: 338 CSALPCLLHLLSSPKESIRKEACWTVSNIT-AGNRAQIQAVIDANIFPVLIEIL 390
Score = 60.1 bits (139), Expect = 6e-09
Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT T+VV+ A+ F LL+ + E + ++AVW L NI N +
Sbjct: 144 LQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAE 203
Query: 208 QVQAVIDAGLLPKIVENLA-KGEFQTQKEAAWAVSNL 315
V++ +LP ++E L T + A WA+SNL
Sbjct: 204 CRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 240
Score = 58.4 bits (135), Expect = 2e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + + W LS ++ G ++QA
Sbjct: 233 AVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQA 292
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 293 VIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 351
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 352 KESIRKEACWTVSNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 408
Query: 580 YFGGDEE 600
GG E
Sbjct: 409 TSGGTPE 415
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G + VI+ G +P ++ L Q++A WA+ N++ E
Sbjct: 147 EAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIA-GDNAECR 205
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLKMAGENADQVANIIEEC 498
++NC ++PP LL S + T N V LSN+ + G+N + + C
Sbjct: 206 DFVLNCEILPPLLELLTNSNRLTTTRNAVW-ALSNLCR--GKNPPPNFSKVSPC 256
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Frame = +1
Query: 214 QAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
Q + G++ + V+ L + E T Q EAAWA++N++ SGT +I G +P F LL
Sbjct: 121 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIA-SGTFLHTKVVIETGAVPIFIKLL 179
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENAD 471
+ + V + L N +AG+NA+
Sbjct: 180 NSEHEDVQEQAVWALGN---IAGDNAE 203
Score = 38.3 bits (85), Expect = 0.021
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A + NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 350 SPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 408
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G +E I
Sbjct: 409 TSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIG--- 465
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 466 INPYCALI 473
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 208 bits (509), Expect = 9e-54
Identities = 102/204 (50%), Positives = 140/204 (68%), Gaps = 7/204 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 305 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNIT 364
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+ L+ G I
Sbjct: 365 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIK 424
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQ-------VANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ + + Q +IEE G+D+IE LQS
Sbjct: 425 PLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKIEFLQS 484
Query: 532 HEKVEIFKMAYDIFEQYFGGDEED 603
HE EI++ A+D+ E YFG +E+D
Sbjct: 485 HENQEIYQKAFDLIEHYFGVEEDD 508
Score = 60.5 bits (140), Expect = 5e-09
Identities = 30/114 (26%), Positives = 58/114 (50%)
Frame = +1
Query: 49 AIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVID 228
A+ + G +++ Q V++ LL H K+ A+ + NI G+ Q Q +++
Sbjct: 275 ALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN 334
Query: 229 AGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
LP ++ L+ + +KEA W VSN++ +G + Q+ A+I+ + P +L
Sbjct: 335 CSALPCLLHLLSSPKESIRKEACWTVSNIT-AGNRAQIQAVIDANIFPVLIEIL 387
Score = 60.1 bits (139), Expect = 6e-09
Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+ NI +GT T+VV+ A+ F LL+ + E + ++AVW L NI N +
Sbjct: 141 LQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAE 200
Query: 208 QVQAVIDAGLLPKIVENLA-KGEFQTQKEAAWAVSNL 315
V++ +LP ++E L T + A WA+SNL
Sbjct: 201 CRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 237
Score = 58.4 bits (135), Expect = 2e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + + W LS ++ G ++QA
Sbjct: 230 AVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKIQA 289
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 290 VIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 348
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 349 KESIRKEACWTVSNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 580 YFGGDEE 600
GG E
Sbjct: 406 TSGGTPE 412
Score = 51.6 bits (118), Expect = 2e-06
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
EA W L+NI +G + VI+ G +P ++ L Q++A WA+ N++ E
Sbjct: 144 EAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIA-GDNAECR 202
Query: 343 GALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLKMAGENADQVANIIEEC 498
++NC ++PP LL S + T N V LSN+ + G+N + + C
Sbjct: 203 DFVLNCEILPPLLELLTNSNRLTTTRNAVW-ALSNLCR--GKNPPPNFSKVSPC 253
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/87 (33%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Frame = +1
Query: 214 QAVIDAGLLPKIVENLAKGEFQT-QKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
Q + G++ + V+ L + E T Q EAAWA++N++ SGT +I G +P F LL
Sbjct: 118 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIA-SGTFLHTKVVIETGAVPIFIKLL 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENAD 471
+ + V + L N +AG+NA+
Sbjct: 177 NSEHEDVQEQAVWALGN---IAGDNAE 200
Score = 38.3 bits (85), Expect = 0.021
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A + NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 347 SPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 405
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G +Q++ ++ G + + + L + + + A + N+ G +E I
Sbjct: 406 TSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIG--- 462
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 463 INPYCALI 470
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 204 bits (498), Expect = 2e-52
Identities = 98/205 (47%), Positives = 137/205 (66%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 307 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+Q VIDA + P ++ L EF+T+KEAAWA++N + G+ EQ+ L+ G I
Sbjct: 367 AGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMA-------GENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ G + +IEE G+D+IE LQS
Sbjct: 427 PLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQS 486
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG ++ED+
Sbjct: 487 HENQEIYQKAFDLIEHYFGTEDEDS 511
Score = 62.1 bits (144), Expect = 1e-09
Identities = 34/158 (21%), Positives = 75/158 (47%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
+ V A A+ + G +++ Q V++ LL H K+ A+ + NI G
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q Q +++ L ++ L+ + +KEA W +SN++ +G + Q+ +I+ + P
Sbjct: 327 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDANIFPAL 385
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIE 492
++L + + ++N +G +A+Q+ ++E
Sbjct: 386 ISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLVE 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + +A W LS ++ G ++QA
Sbjct: 232 AVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQA 291
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VIDAG+ ++VE L +++ A AV N+ V+G Q ++NC + +LLS
Sbjct: 292 VIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQSLLHLLSSP 350
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ I LQ+ E + A+ I
Sbjct: 351 KESIKKEACWTISNI--TAGNRA-QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 580 YFGGDEE 600
GG E
Sbjct: 408 TSGGSAE 414
Score = 58.0 bits (134), Expect = 2e-08
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VL+C+ L L S Q + + AVW LSN+ G
Sbjct: 185 VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKS 244
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + L + L + +A WA+S LS G +++ A+I+ GV
Sbjct: 245 PPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLS-DGPNDKIQAVIDAGVCRRLVE 303
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V++ L + N+ + G+ D +I C + + L S K I K A
Sbjct: 304 LLMHNDYKVVSPALRAVGNI--VTGD--DIQTQVILNCSALQSLLHLLSSPKESIKKEA 358
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 58 NIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGL 237
NI +G QT++V+ A+ F LLS + E + ++AVW L NI + V+D +
Sbjct: 153 NIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNI 212
Query: 238 LPKIVENLAKGEFQTQ-KEAAWAVSNL 315
LP +++ +K T + A WA+SNL
Sbjct: 213 LPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.4 bits (125), Expect = 3e-07
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +GN Q + VI A +P +E L+ Q++A WA+ N++ T +
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCR- 204
Query: 343 GALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 450
+++C ++PP L S ++ T N V LSN+ +
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + ++L + + KEA W ++N
Sbjct: 349 SPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G+ +Q++ +++ G + + + L + + + A + N+ G +E A N
Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE---AKRNGTG 464
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 465 INPYCALI 472
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 204 bits (498), Expect = 2e-52
Identities = 98/205 (47%), Positives = 137/205 (66%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 307 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+Q VIDA + P ++ L EF+T+KEAAWA++N + G+ EQ+ L+ G I
Sbjct: 367 AGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMA-------GENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ G + +IEE G+D+IE LQS
Sbjct: 427 PLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQS 486
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG ++ED+
Sbjct: 487 HENQEIYQKAFDLIEHYFGTEDEDS 511
Score = 62.1 bits (144), Expect = 1e-09
Identities = 34/158 (21%), Positives = 75/158 (47%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
+ V A A+ + G +++ Q V++ LL H K+ A+ + NI G
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q Q +++ L ++ L+ + +KEA W +SN++ +G + Q+ +I+ + P
Sbjct: 327 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDANIFPAL 385
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIE 492
++L + + ++N +G +A+Q+ ++E
Sbjct: 386 ISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLVE 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + +A W LS ++ G ++QA
Sbjct: 232 AVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQA 291
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VIDAG+ ++VE L +++ A AV N+ V+G Q ++NC + +LLS
Sbjct: 292 VIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQSLLHLLSSP 350
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ I LQ+ E + A+ I
Sbjct: 351 KESIKKEACWTISNI--TAGNRA-QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 580 YFGGDEE 600
GG E
Sbjct: 408 TSGGSAE 414
Score = 58.0 bits (134), Expect = 2e-08
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VL+C+ L L S Q + + AVW LSN+ G
Sbjct: 185 VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKS 244
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + L + L + +A WA+S LS G +++ A+I+ GV
Sbjct: 245 PPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLS-DGPNDKIQAVIDAGVCRRLVE 303
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V++ L + N+ + G+ D +I C + + L S K I K A
Sbjct: 304 LLMHNDYKVVSPALRAVGNI--VTGD--DIQTQVILNCSALQSLLHLLSSPKESIKKEA 358
Score = 57.6 bits (133), Expect = 3e-08
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +GN Q + VI AG +P +E L+ Q++A WA+ N++ T +
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCR- 204
Query: 343 GALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 450
+++C ++PP L S ++ T N V LSN+ +
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 58 NIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGL 237
NI +G QT++V+ A+ F LLS + E + ++AVW L NI + V+D +
Sbjct: 153 NIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNI 212
Query: 238 LPKIVENLAKGEFQTQ-KEAAWAVSNL 315
LP +++ +K T + A WA+SNL
Sbjct: 213 LPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + ++L + + KEA W ++N
Sbjct: 349 SPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G+ +Q++ +++ G + + + L + + + A + N+ G +E A N
Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE---AKRNGTG 464
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 465 INPYCALI 472
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 204 bits (498), Expect = 2e-52
Identities = 98/205 (47%), Positives = 137/205 (66%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 307 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+Q VIDA + P ++ L EF+T+KEAAWA++N + G+ EQ+ L+ G I
Sbjct: 367 AGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMA-------GENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ G + +IEE G+D+IE LQS
Sbjct: 427 PLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQS 486
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG ++ED+
Sbjct: 487 HENQEIYQKAFDLIEHYFGTEDEDS 511
Score = 62.1 bits (144), Expect = 1e-09
Identities = 34/158 (21%), Positives = 75/158 (47%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
+ V A A+ + G +++ Q V++ LL H K+ A+ + NI G
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q Q +++ L ++ L+ + +KEA W +SN++ +G + Q+ +I+ + P
Sbjct: 327 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDANIFPAL 385
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIE 492
++L + + ++N +G +A+Q+ ++E
Sbjct: 386 ISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLVE 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + +A W LS ++ G ++QA
Sbjct: 232 AVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQA 291
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VIDAG+ ++VE L +++ A AV N+ V+G Q ++NC + +LLS
Sbjct: 292 VIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQSLLHLLSSP 350
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ I LQ+ E + A+ I
Sbjct: 351 KESIKKEACWTISNI--TAGNRA-QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 580 YFGGDEE 600
GG E
Sbjct: 408 TSGGSAE 414
Score = 58.0 bits (134), Expect = 2e-08
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VL+C+ L L S Q + + AVW LSN+ G
Sbjct: 185 VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKS 244
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + L + L + +A WA+S LS G +++ A+I+ GV
Sbjct: 245 PPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLS-DGPNDKIQAVIDAGVCRRLVE 303
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V++ L + N+ + G+ D +I C + + L S K I K A
Sbjct: 304 LLMHNDYKVVSPALRAVGNI--VTGD--DIQTQVILNCSALQSLLHLLSSPKESIKKEA 358
Score = 57.6 bits (133), Expect = 3e-08
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +GN Q + VI AG +P +E L+ Q++A WA+ N++ T +
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCR- 204
Query: 343 GALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 450
+++C ++PP L S ++ T N V LSN+ +
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 58 NIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGL 237
NI +G QT++V+ A+ F LLS + E + ++AVW L NI + V+D +
Sbjct: 153 NIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNI 212
Query: 238 LPKIVENLAKGEFQTQ-KEAAWAVSNL 315
LP +++ +K T + A WA+SNL
Sbjct: 213 LPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + ++L + + KEA W ++N
Sbjct: 349 SPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G+ +Q++ +++ G + + + L + + + A + N+ G +E A N
Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE---AKRNGTG 464
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 465 INPYCALI 472
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 204 bits (498), Expect = 2e-52
Identities = 98/205 (47%), Positives = 137/205 (66%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 307 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+Q VIDA + P ++ L EF+T+KEAAWA++N + G+ EQ+ L+ G I
Sbjct: 367 AGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMA-------GENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ G + +IEE G+D+IE LQS
Sbjct: 427 PLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQS 486
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG ++ED+
Sbjct: 487 HENQEIYQKAFDLIEHYFGTEDEDS 511
Score = 62.1 bits (144), Expect = 1e-09
Identities = 34/158 (21%), Positives = 75/158 (47%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
+ V A A+ + G +++ Q V++ LL H K+ A+ + NI G
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q Q +++ L ++ L+ + +KEA W +SN++ +G + Q+ +I+ + P
Sbjct: 327 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDANIFPAL 385
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIE 492
++L + + ++N +G +A+Q+ ++E
Sbjct: 386 ISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLVE 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VL+C+ L L S Q + + AVW LSN+ G
Sbjct: 185 VQEQAVWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKS 244
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + L + L + +A WA+S LS G +++ A+I+ GV
Sbjct: 245 PPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLS-DGPNDKIQAVIDAGVCRRLVE 303
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V++ L + N+ + G+ D +I C + + L S K I K A
Sbjct: 304 LLMHNDYKVVSPALRAVGNI--VTGD--DIQTQVILNCSALQSLLHLLSSPKESIKKEA 358
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + +A W LS ++ G ++QA
Sbjct: 232 AVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQA 291
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VIDAG+ ++VE L +++ A AV N+ V+G Q ++NC + +LLS
Sbjct: 292 VIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQSLLHLLSSP 350
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ I LQ+ E + A+ I
Sbjct: 351 KESIKKEACWTISNI--TAGNRA-QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 580 YFGGDEE 600
GG E
Sbjct: 408 TSGGSAE 414
Score = 58.4 bits (135), Expect = 2e-08
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +GN Q + VI AG +P +E L+ Q++A WA+ N++ T +
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMYR- 204
Query: 343 GALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 450
+++C ++PP L S ++ T N V LSN+ +
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 57.2 bits (132), Expect = 4e-08
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 58 NIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGL 237
NI +G QT++V+ A+ F LLS + E + ++AVW L NI + V+D +
Sbjct: 153 NIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMYRDYVLDCNI 212
Query: 238 LPKIVENLAKGEFQTQ-KEAAWAVSNL 315
LP +++ +K T + A WA+SNL
Sbjct: 213 LPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + ++L + + KEA W ++N
Sbjct: 349 SPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G+ +Q++ +++ G + + + L + + + A + N+ G +E A N
Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE---AKRNGTG 464
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 465 INPYCALI 472
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 204 bits (498), Expect = 2e-52
Identities = 98/205 (47%), Positives = 137/205 (66%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 307 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+Q VIDA + P ++ L EF+T+KEAAWA++N + G+ EQ+ L+ G I
Sbjct: 367 AGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMA-------GENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ G + +IEE G+D+IE LQS
Sbjct: 427 PLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQS 486
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG ++ED+
Sbjct: 487 HENQEIYQKAFDLIEHYFGTEDEDS 511
Score = 62.1 bits (144), Expect = 1e-09
Identities = 34/158 (21%), Positives = 75/158 (47%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
+ V A A+ + G +++ Q V++ LL H K+ A+ + NI G
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q Q +++ L ++ L+ + +KEA W +SN++ +G + Q+ +I+ + P
Sbjct: 327 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDANIFPAL 385
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIE 492
++L + + ++N +G +A+Q+ ++E
Sbjct: 386 ISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLVE 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + +A W LS ++ G ++QA
Sbjct: 232 AVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQA 291
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VIDAG+ ++VE L +++ A AV N+ V+G Q ++NC + +LLS
Sbjct: 292 VIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQSLLHLLSSP 350
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ I LQ+ E + A+ I
Sbjct: 351 KESIKKEACWTISNI--TAGNRA-QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 580 YFGGDEE 600
GG E
Sbjct: 408 TSGGSAE 414
Score = 58.0 bits (134), Expect = 2e-08
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VL+C+ L L S Q + + AVW LSN+ G
Sbjct: 185 VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKS 244
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + L + L + +A WA+S LS G +++ A+I+ GV
Sbjct: 245 PPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLS-DGPNDKIQAVIDAGVCRRLVE 303
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V++ L + N+ + G+ D +I C + + L S K I K A
Sbjct: 304 LLMHNDYKVVSPALRAVGNI--VTGD--DIQTQVILNCSALQSLLHLLSSPKESIKKEA 358
Score = 57.6 bits (133), Expect = 3e-08
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +GN Q + VI AG +P +E L+ Q++A WA+ N++ T +
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCR- 204
Query: 343 GALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 450
+++C ++PP L S ++ T N V LSN+ +
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 58 NIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGL 237
NI +G QT++V+ A+ F LLS + E + ++AVW L NI + V+D +
Sbjct: 153 NIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNI 212
Query: 238 LPKIVENLAKGEFQTQ-KEAAWAVSNL 315
LP +++ +K T + A WA+SNL
Sbjct: 213 LPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + ++L + + KEA W ++N
Sbjct: 349 SPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G+ +Q++ +++ G + + + L + + + A + N+ G +E A N
Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE---AKRNGTG 464
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 465 INPYCALI 472
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 204 bits (498), Expect = 2e-52
Identities = 98/205 (47%), Positives = 137/205 (66%), Gaps = 7/205 (3%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 307 HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT 366
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
AGN+ Q+Q VIDA + P ++ L EF+T+KEAAWA++N + G+ EQ+ L+ G I
Sbjct: 367 AGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK 426
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMA-------GENADQVANIIEECGGIDQIEALQS 531
P C+LL+ D++++ V L+GL N+L++ G + +IEE G+D+IE LQS
Sbjct: 427 PLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQS 486
Query: 532 HEKVEIFKMAYDIFEQYFGGDEEDA 606
HE EI++ A+D+ E YFG ++ED+
Sbjct: 487 HENQEIYQKAFDLIEHYFGTEDEDS 511
Score = 62.1 bits (144), Expect = 1e-09
Identities = 34/158 (21%), Positives = 75/158 (47%)
Frame = +1
Query: 19 EVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAG 198
+ V A A+ + G +++ Q V++ LL H K+ A+ + NI G
Sbjct: 267 DTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 326
Query: 199 NKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPF 378
+ Q Q +++ L ++ L+ + +KEA W +SN++ +G + Q+ +I+ + P
Sbjct: 327 DDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDANIFPAL 385
Query: 379 CNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIE 492
++L + + ++N +G +A+Q+ ++E
Sbjct: 386 ISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLVE 421
Score = 58.8 bits (136), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + L+ LL + +A W LS ++ G ++QA
Sbjct: 232 AVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQA 291
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VIDAG+ ++VE L +++ A AV N+ V+G Q ++NC + +LLS
Sbjct: 292 VIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQVILNCSALQSLLHLLSSP 350
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ I LQ+ E + A+ I
Sbjct: 351 KESIKKEACWTISNI--TAGNRA-QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 580 YFGGDEE 600
GG E
Sbjct: 408 TSGGSAE 414
Score = 58.0 bits (134), Expect = 2e-08
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 1/179 (0%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNK 204
VQ A+ A+GNI + VL+C+ L L S Q + + AVW LSN+ G
Sbjct: 185 VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKS 244
Query: 205 QQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCN 384
+ + L + L + +A WA+S LS G +++ A+I+ GV
Sbjct: 245 PPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLS-DGPNDKIQAVIDAGVCRRLVE 303
Query: 385 LLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
LL D +V++ L + N+ + G+ D +I C + + L S K I K A
Sbjct: 304 LLMHNDYKVVSPALRAVGNI--VTGD--DIQTQVILNCSALQSLLHLLSSPKESIKKEA 358
Score = 57.6 bits (133), Expect = 3e-08
Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = +1
Query: 163 EAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
E+ W L+NI +GN Q + VI AG +P +E L+ Q++A WA+ N++ T +
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCR- 204
Query: 343 GALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 450
+++C ++PP L S ++ T N V LSN+ +
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Frame = +1
Query: 58 NIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGL 237
NI +G QT++V+ A+ F LLS + E + ++AVW L NI + V+D +
Sbjct: 153 NIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNI 212
Query: 238 LPKIVENLAKGEFQTQ-KEAAWAVSNL 315
LP +++ +K T + A WA+SNL
Sbjct: 213 LPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + ++L + + KEA W ++N
Sbjct: 349 SPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNA 407
Query: 190 TA-GNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGV 366
T+ G+ +Q++ +++ G + + + L + + + A + N+ G +E A N
Sbjct: 408 TSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE---AKRNGTG 464
Query: 367 IPPFCNLL 390
I P+C L+
Sbjct: 465 INPYCALI 472
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 136 bits (330), Expect = 4e-32
Identities = 65/110 (59%), Positives = 81/110 (73%)
Frame = +1
Query: 13 HKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNIT 192
H + KV + ALRA+GNIVTG D QTQV+LNC AL LLS KE I KEA W +SNIT
Sbjct: 212 HNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT 271
Query: 193 AGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQV 342
AGN+ Q+QAVIDA + P ++E L K EF+T+KEAAWA++N + GT EQ+
Sbjct: 272 AGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 321
Score = 62.5 bits (145), Expect = 1e-09
Identities = 51/187 (27%), Positives = 84/187 (44%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQVQA 219
A+ A+ N+ G + + L LL + +A W LS ++ G +++QA
Sbjct: 137 AVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQA 196
Query: 220 VIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
VID+G+ ++VE L +++ A AV N+ V+G Q ++NC +P +LLS
Sbjct: 197 VIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQVILNCSALPCLLHLLSSP 255
Query: 400 DTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMAYDIFEQ 579
+ +SN+ AG A Q+ +I+ IE LQ E + A+ I
Sbjct: 256 KESIRKEACWTISNI--TAGNRA-QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 312
Query: 580 YFGGDEE 600
GG E
Sbjct: 313 TSGGTPE 319
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/175 (28%), Positives = 77/175 (44%), Gaps = 1/175 (0%)
Frame = +1
Query: 40 ALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKE-KICKEAVWFLSNITAGNKQQVQ 216
A+ A+GNI + VLNC L+ LL+ + + AVW LSN+ G +
Sbjct: 94 AVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPE 153
Query: 217 AVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSC 396
+ LP + L + +A WA+S LS G E++ A+I+ GV LL
Sbjct: 154 FAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVELLMH 212
Query: 397 KDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIFKMA 561
D +V + L + N+ + G+ D +I C + + L S K I K A
Sbjct: 213 NDYKVASPALRAVGNI--VTGD--DIQTQVILNCSALPCLLHLLSSPKESIRKEA 263
Score = 32.7 bits (71), Expect = 1.0
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +1
Query: 10 SHKEVKVQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNI 189
S KE ++ A I NI G Q Q V++ + +L + + KEA W ++N
Sbjct: 254 SPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNA 312
Query: 190 TAG 198
T+G
Sbjct: 313 TSG 315
>AL135901-9|CAI40722.1| 90|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 90
Score = 110 bits (265), Expect = 3e-24
Identities = 47/77 (61%), Positives = 62/77 (80%)
Frame = +1
Query: 373 PFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQVANIIEECGGIDQIEALQSHEKVEIF 552
PFCNLLS KD+QV+ VVLDGL N+L MAG+ A +A IIEECGG+++IE LQ HE +I+
Sbjct: 1 PFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIY 60
Query: 553 KMAYDIFEQYFGGDEED 603
K+A++I +QYF GD+ D
Sbjct: 61 KLAFEIIDQYFSGDDID 77
>AL132795-7|CAI20502.1| 121|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 121
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/92 (40%), Positives = 59/92 (64%), Gaps = 7/92 (7%)
Frame = +1
Query: 349 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGENADQ-------VANIIEECGGI 507
L+ G I P C+LL+ D++++ V L+GL N+L++ + + Q +IEE G+
Sbjct: 2 LVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGL 61
Query: 508 DQIEALQSHEKVEIFKMAYDIFEQYFGGDEED 603
D+IE LQSHE EI++ A+D+ E YFG +E+D
Sbjct: 62 DKIEFLQSHENQEIYQKAFDLIEHYFGVEEDD 93
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 54.8 bits (126), Expect = 2e-07
Identities = 39/151 (25%), Positives = 69/151 (45%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSRAVVDAGAVPLLVLCI 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + LS++ K + E A V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 54.8 bits (126), Expect = 2e-07
Identities = 39/151 (25%), Positives = 69/151 (45%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + LS++ K + E A V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 54.8 bits (126), Expect = 2e-07
Identities = 39/151 (25%), Positives = 69/151 (45%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + LS++ K + E A V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 54.8 bits (126), Expect = 2e-07
Identities = 39/151 (25%), Positives = 69/151 (45%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + LS++ K + E A V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 54.8 bits (126), Expect = 2e-07
Identities = 39/151 (25%), Positives = 69/151 (45%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + LS++ K + E A V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 54.8 bits (126), Expect = 2e-07
Identities = 39/151 (25%), Positives = 69/151 (45%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLL 390
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 391 SCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + LS++ K + E A V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/152 (23%), Positives = 68/152 (44%)
Frame = +1
Query: 28 VQTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQ 207
+Q A A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 57 IQQIAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQ 116
Query: 208 QVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNL 387
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P
Sbjct: 117 LAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLC 175
Query: 388 LSCKDTQVINVVLDGLSNMLKMAGENADQVAN 483
+ + + + LS+++K + E A V +
Sbjct: 176 IQEPEIALKGIAASALSDIVKHSPELAQTVVD 207
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 50.8 bits (116), Expect = 4e-06
Identities = 33/114 (28%), Positives = 55/114 (48%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 135 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 193
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P
Sbjct: 194 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 50.8 bits (116), Expect = 4e-06
Identities = 33/114 (28%), Positives = 55/114 (48%)
Frame = +1
Query: 31 QTAALRAIGNIVTGTDEQTQVVLNCDALSHFPALLSHQKEKICKEAVWFLSNITAGNKQQ 210
QTAAL A+G + D+ + V+ CD L L+ Q K A + L + + Q
Sbjct: 135 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 193
Query: 211 VQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIP 372
QA++D G L +V L + ++ AAWA+ ++ E A+++ G +P
Sbjct: 194 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVP 246
>BC044907-1|AAH44907.1| 801|Homo sapiens ANKAR protein protein.
Length = 801
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 166 AVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVG 345
AV L I N Q + ++DAG +P ++ L + + Q + +SN+S K V
Sbjct: 484 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNISTH--KSAVH 541
Query: 346 ALINCGVIPPFCNLLSCKDTQV 411
AL+ G IP NLL C + +V
Sbjct: 542 ALVEAGGIPSLINLLVCDEPEV 563
>AK126073-1|BAC86425.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ44085 fis, clone TESTI4041053. ).
Length = 1080
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 166 AVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVG 345
AV L I N Q + ++DAG +P ++ L + + Q + +SN+S K V
Sbjct: 720 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNISTH--KSAVH 777
Query: 346 ALINCGVIPPFCNLLSCKDTQV 411
AL+ G IP NLL C + +V
Sbjct: 778 ALVEAGGIPSLINLLVCDEPEV 799
>AJ549812-1|CAD71147.1| 1363|Homo sapiens hypothetical protein
protein.
Length = 1363
Score = 47.6 bits (108), Expect = 3e-05
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 166 AVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVSGTKEQVG 345
AV L I N Q + ++DAG +P ++ L + + Q + +SN+S K V
Sbjct: 649 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSNISTH--KSAVH 706
Query: 346 ALINCGVIPPFCNLLSCKDTQV 411
AL+ G IP NLL C + +V
Sbjct: 707 ALVEAGGIPSLINLLVCDEPEV 728
>U51269-1|AAC51202.1| 962|Homo sapiens armadillo repeat protein
protein.
Length = 962
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
Frame = +1
Query: 127 ALLSHQKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAV 306
A+L H + + A +L ++ N+ + V LP +V L + ++ A A+
Sbjct: 365 AMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGAL 424
Query: 307 SNLSVSGTKEQVGALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 444
NLS + A+ +CG +P LL + +D +V +V L N+
Sbjct: 425 RNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNL 471
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 35.5 bits (78), Expect = 0.15
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Frame = +1
Query: 178 LSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVS-GTKEQVGALI 354
+ N GN +Q +I G +P+++ L + T+ + AV S++ GT+ V +L+
Sbjct: 29 MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLL 88
Query: 355 NCGVIPPFCNLLSCKDTQVINVVL 426
+C +IP L D + I L
Sbjct: 89 DCHIIPALLQGLLSPDLKFIEACL 112
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 35.5 bits (78), Expect = 0.15
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Frame = +1
Query: 178 LSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVS-GTKEQVGALI 354
+ N GN +Q +I G +P+++ L + T+ + AV S++ GT+ V +L+
Sbjct: 29 MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLL 88
Query: 355 NCGVIPPFCNLLSCKDTQVINVVL 426
+C +IP L D + I L
Sbjct: 89 DCHIIPALLQGLLSPDLKFIEACL 112
>BC013424-1|AAH13424.1| 385|Homo sapiens armadillo repeat
containing 8 protein.
Length = 385
Score = 35.5 bits (78), Expect = 0.15
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Frame = +1
Query: 178 LSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQTQKEAAWAVSNLSVS-GTKEQVGALI 354
+ N GN +Q +I G +P+++ L + T+ + AV S++ GT+ V +L+
Sbjct: 29 MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLL 88
Query: 355 NCGVIPPFCNLLSCKDTQVINVVL 426
+C +IP L D + I L
Sbjct: 89 DCHIIPALLQGLLSPDLKFIEACL 112
>AK023749-1|BAB14666.1| 875|Homo sapiens protein ( Homo sapiens
cDNA FLJ13687 fis, clone PLACE2000061. ).
Length = 875
Score = 34.7 bits (76), Expect = 0.26
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = -2
Query: 304 RPTQPPSESGTRPWPGSPLSWARGRRR*LPALVAYSRLLY 185
+P+ S T PWPG P+ RG + LP +V S+ Y
Sbjct: 475 KPSSSSSGPRTLPWPGQPIRGCRGPQAALPPVVILSKAAY 514
>AK001721-1|BAA91861.1| 443|Homo sapiens protein ( Homo sapiens
cDNA FLJ10859 fis, clone NT2RP4001567, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 443
Score = 34.7 bits (76), Expect = 0.26
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Frame = +1
Query: 178 LSNITAGNKQQVQAVIDAGLLPKIVENLAKGEFQT--QKEAAWAVSNLSVSGTKEQVGAL 351
+ N GN +Q +I G +P+++ L + T + E A + +L++ GT+ V +L
Sbjct: 1 MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTGLKTECAVVLGSLAM-GTENNVKSL 59
Query: 352 INCGVIPPFCNLLSCKDTQVINVVL 426
++C +IP L D + I L
Sbjct: 60 LDCHIIPALLQGLLSPDLKFIEACL 84
>U31468-1|AAC03241.1| 347|Homo sapiens homeobox protein protein.
Length = 347
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Frame = +2
Query: 449 RWPGRTRTKWPTSSR-----SAGESTRSRRCRATRKSKYLRWRMISLNSTSVETRRTR 607
R P R + P SSR +A STR RRCR TR++ W + S S RR R
Sbjct: 114 RRPSTRRRQRPASSRRSRCPAAVTSTRRRRCRLTRRTAKASWPKRARCSPSPRPRRCR 171
>AB058756-1|BAB47482.1| 708|Homo sapiens KIAA1853 protein protein.
Length = 708
Score = 32.7 bits (71), Expect = 1.0
Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Frame = +2
Query: 326 APRNKSGLSSTAESYRPSAIYSAAKTRKSLTLCWTG*ATC*RWPGRTRTKWPTSSRSAGE 505
+P + LSST+ Y S+ SA++ S + W+ + R RTRT +SSRS
Sbjct: 620 SPSSSGSLSSTSSWYSSSSSRSASR---SYSRSWSRSRS--RRRSRTRTSSSSSSRSPSP 674
Query: 506 STRSR-RCRATRKSK 547
+RSR R R+ +S+
Sbjct: 675 GSRSRSRSRSRSRSR 689
>M60495-1|AAA63245.1| 200|Homo sapiens profilaggrin protein.
Length = 200
Score = 31.9 bits (69), Expect = 1.8
Identities = 18/66 (27%), Positives = 28/66 (42%)
Frame = +3
Query: 339 SRGSHQLRSHTALLQSTQLQRHASH*RCVGRVEQHAEDGRGERGPSGQHHRGVRGNRPDR 518
+R H+ S L +S +R S E H+ED G + ++HRG +
Sbjct: 50 NRSRHENTSQVPLQESRTRKRRGSRVSQDSDSEGHSEDSERHSGSASRNHRGSAWEQSRD 109
Query: 519 GAAEPR 536
G+ PR
Sbjct: 110 GSRHPR 115
>X88824-1|CAA61294.1| 127|Homo sapiens immunoglobulin V(H) gene
V-D-J protein.
Length = 127
Score = 30.3 bits (65), Expect = 5.5
Identities = 13/45 (28%), Positives = 24/45 (53%)
Frame = +1
Query: 265 KGEFQTQKEAAWAVSNLSVSGTKEQVGALINCGVIPPFCNLLSCK 399
KG F ++ A +L ++ + + AL C +IP +C+ SC+
Sbjct: 65 KGRFTISRDNAKNTLHLQMTSLRVEDTALYYCVIIPGYCSTTSCE 109
>M94173-1|AAA51898.1| 2237|Homo sapiens N-type calcium channel alpha-1
subunit protein.
Length = 2237
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>M94172-1|AAA51897.1| 2339|Homo sapiens N-type calcium channel alpha-1
subunit protein.
Length = 2339
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>M68956-1|AAA59555.1| 332|Homo sapiens myristoylated alanine-rich
C-kinase substrate protein.
Length = 332
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/64 (28%), Positives = 28/64 (43%)
Frame = +3
Query: 123 PSLVISSEREDLQRSSMVPI*YNSRE*ATSAGSHRRRPLAQDSGEPGQGRVPDSEGGCVG 302
P+ S +E+LQ + P +E +AGS P A + GEP P++ V
Sbjct: 47 PAAAESGAKEELQANGSAPA--ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
Query: 303 RLQP 314
+ P
Sbjct: 105 KEAP 108
>DQ341274-1|ABC67467.1| 332|Homo sapiens myristoylated alanine-rich
protein kinase C substrate protein.
Length = 332
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/64 (28%), Positives = 28/64 (43%)
Frame = +3
Query: 123 PSLVISSEREDLQRSSMVPI*YNSRE*ATSAGSHRRRPLAQDSGEPGQGRVPDSEGGCVG 302
P+ S +E+LQ + P +E +AGS P A + GEP P++ V
Sbjct: 47 PAAAESGAKEELQANGSAPA--ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
Query: 303 RLQP 314
+ P
Sbjct: 105 KEAP 108
>BC089040-1|AAH89040.1| 332|Homo sapiens myristoylated alanine-rich
protein kinase C substrate protein.
Length = 332
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/64 (28%), Positives = 28/64 (43%)
Frame = +3
Query: 123 PSLVISSEREDLQRSSMVPI*YNSRE*ATSAGSHRRRPLAQDSGEPGQGRVPDSEGGCVG 302
P+ S +E+LQ + P +E +AGS P A + GEP P++ V
Sbjct: 47 PAAAESGAKEELQANGSAPA--ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
Query: 303 RLQP 314
+ P
Sbjct: 105 KEAP 108
>BC068059-1|AAH68059.1| 157|Homo sapiens MARCKS protein protein.
Length = 157
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/64 (28%), Positives = 28/64 (43%)
Frame = +3
Query: 123 PSLVISSEREDLQRSSMVPI*YNSRE*ATSAGSHRRRPLAQDSGEPGQGRVPDSEGGCVG 302
P+ S +E+LQ + P +E +AGS P A + GEP P++ V
Sbjct: 47 PAAAESGAKEELQANGSAPA--ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
Query: 303 RLQP 314
+ P
Sbjct: 105 KEAP 108
>BC013004-1|AAH13004.1| 157|Homo sapiens MARCKS protein protein.
Length = 157
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/64 (28%), Positives = 28/64 (43%)
Frame = +3
Query: 123 PSLVISSEREDLQRSSMVPI*YNSRE*ATSAGSHRRRPLAQDSGEPGQGRVPDSEGGCVG 302
P+ S +E+LQ + P +E +AGS P A + GEP P++ V
Sbjct: 47 PAAAESGAKEELQANGSAPA--ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
Query: 303 RLQP 314
+ P
Sbjct: 105 KEAP 108
>AL772363-4|CAI17142.1| 2337|Homo sapiens calcium channel,
voltage-dependent, N type, alphar), member 6 protein.
Length = 2337
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>AL772363-3|CAI17144.1| 2339|Homo sapiens calcium channel,
voltage-dependent, N type, alpha protein.
Length = 2339
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>AL772363-2|CAI17143.1| 2338|Homo sapiens calcium channel,
voltage-dependent, N type, alpha protein.
Length = 2338
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 890 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 937
>AL772363-1|CAI17141.1| 2237|Homo sapiens calcium channel,
voltage-dependent, N type, alpha7a (RPL7A) protein.
Length = 2237
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>AL591424-4|CAI40688.1| 2337|Homo sapiens calcium channel,
voltage-dependent, N type, alpha(TBP)-associated factor,
100kD protein.
Length = 2337
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>AL591424-3|CAI40687.1| 2339|Homo sapiens calcium channel,
voltage-dependent, N type, alphabeta family protein.
Length = 2339
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>AL591424-2|CAI40686.1| 2338|Homo sapiens calcium channel,
voltage-dependent, N type, alphaate 3A protein.
Length = 2338
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 890 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 937
>AL591424-1|CAI40685.1| 2237|Homo sapiens calcium channel,
voltage-dependent, N type, alpha, alpha protein.
Length = 2237
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Frame = +3
Query: 402 HASH*R-CVGRVEQHAEDGRGERGPSG--QHHRGVRGNRPDRGAAEPRESR 545
H SH + G E +E GRG GP G +HHR RG+ + EPR R
Sbjct: 889 HRSHSKEAAGPPEARSERGRGP-GPEGGRRHHR--RGSPEEAAEREPRRHR 936
>AL132660-2|CAI19942.1| 332|Homo sapiens myristoylated alanine-rich
protein kinase C substrate protein.
Length = 332
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/64 (28%), Positives = 28/64 (43%)
Frame = +3
Query: 123 PSLVISSEREDLQRSSMVPI*YNSRE*ATSAGSHRRRPLAQDSGEPGQGRVPDSEGGCVG 302
P+ S +E+LQ + P +E +AGS P A + GEP P++ V
Sbjct: 47 PAAAESGAKEELQANGSAPA--ADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVE 104
Query: 303 RLQP 314
+ P
Sbjct: 105 KEAP 108
>AK123353-1|BAC85591.1| 195|Homo sapiens DC3) mRNA. protein.
Length = 195
Score = 29.9 bits (64), Expect = 7.3
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Frame = -1
Query: 509 SIPPHSSMMLATWSAFSPAIFSMLL---NPSNTTLMTCVSLQLSRLQKGGMTPQLMRAPT 339
S PP S L T +FSPA++S LL + +C S LS K P RA
Sbjct: 105 SHPPRSPAALPTLKSFSPAMYSALLVSHSSPKAYTFSCYSRALSSSLKEHTYPH--RATH 162
Query: 338 CSLVPLTLRL 309
C + + L +
Sbjct: 163 CGHMNIVLHI 172
>BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family 8,
subfamily B, polypeptide 1 protein.
Length = 501
Score = 29.5 bits (63), Expect = 9.7
Identities = 10/24 (41%), Positives = 16/24 (66%)
Frame = -2
Query: 307 RRPTQPPSESGTRPWPGSPLSWAR 236
RRP +PP + GT PW G +++ +
Sbjct: 28 RRPWEPPLDKGTVPWLGHAMAFRK 51
>BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family 8,
subfamily B, polypeptide 1 protein.
Length = 501
Score = 29.5 bits (63), Expect = 9.7
Identities = 10/24 (41%), Positives = 16/24 (66%)
Frame = -2
Query: 307 RRPTQPPSESGTRPWPGSPLSWAR 236
RRP +PP + GT PW G +++ +
Sbjct: 28 RRPWEPPLDKGTVPWLGHAMAFRK 51
>BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family 8,
subfamily B, polypeptide 1 protein.
Length = 501
Score = 29.5 bits (63), Expect = 9.7
Identities = 10/24 (41%), Positives = 16/24 (66%)
Frame = -2
Query: 307 RRPTQPPSESGTRPWPGSPLSWAR 236
RRP +PP + GT PW G +++ +
Sbjct: 28 RRPWEPPLDKGTVPWLGHAMAFRK 51
>BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family 8,
subfamily B, polypeptide 1 protein.
Length = 501
Score = 29.5 bits (63), Expect = 9.7
Identities = 10/24 (41%), Positives = 16/24 (66%)
Frame = -2
Query: 307 RRPTQPPSESGTRPWPGSPLSWAR 236
RRP +PP + GT PW G +++ +
Sbjct: 28 RRPWEPPLDKGTVPWLGHAMAFRK 51
>BC002872-1|AAH02872.1| 339|Homo sapiens KIAA0515 protein protein.
Length = 339
Score = 29.5 bits (63), Expect = 9.7
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = -2
Query: 316 SGWRRPTQPPSESGTRPWPGSPLSWAR 236
S ++PTQ S+ T PG P SWA+
Sbjct: 120 SNLQKPTQSISQENTNSVPGGPKSWAQ 146
>AL358781-1|CAI40214.1| 1535|Homo sapiens KIAA0515 protein.
Length = 1535
Score = 29.5 bits (63), Expect = 9.7
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = -2
Query: 316 SGWRRPTQPPSESGTRPWPGSPLSWAR 236
S ++PTQ S+ T PG P SWA+
Sbjct: 120 SNLQKPTQSISQENTNSVPGGPKSWAQ 146
>AF090320-1|AAD19877.1| 501|Homo sapiens sterol
12-alpha-hydroxylase CYP8B1 protein.
Length = 501
Score = 29.5 bits (63), Expect = 9.7
Identities = 10/24 (41%), Positives = 16/24 (66%)
Frame = -2
Query: 307 RRPTQPPSESGTRPWPGSPLSWAR 236
RRP +PP + GT PW G +++ +
Sbjct: 28 RRPWEPPLDKGTVPWLGHAMAFRK 51
>AB046765-1|BAB13371.2| 968|Homo sapiens KIAA1545 protein protein.
Length = 968
Score = 29.5 bits (63), Expect = 9.7
Identities = 18/57 (31%), Positives = 28/57 (49%)
Frame = +3
Query: 219 SHRRRPLAQDSGEPGQGRVPDSEGGCVGRLQPER*RHQGTSRGSHQLRSHTALLQST 389
S RRPL ++G PGQ P +G LQP + S+G + ++L++T
Sbjct: 54 SENRRPL--EAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEAT 108
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,085,880
Number of Sequences: 237096
Number of extensions: 2227215
Number of successful extensions: 11975
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 11018
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11829
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6466646650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
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