Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0009_E03
(484 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U84401-1|AAB41788.1| 787|Homo sapiens smoothened protein. 78 1e-14
BC009989-1|AAH09989.1| 787|Homo sapiens smoothened homolog (Dro... 78 1e-14
AF120103-1|AAF31757.1| 787|Homo sapiens Gx protein protein. 78 1e-14
AF114821-1|AAD17202.1| 787|Homo sapiens smoothened protein. 78 1e-14
AF071494-1|AAC24863.1| 787|Homo sapiens Gx protein protein. 78 1e-14
DQ420628-1|ABD83351.1| 346|Homo sapiens secreted frizzled-relat... 39 0.011
CR541755-1|CAG46555.1| 346|Homo sapiens SFRP4 protein. 39 0.011
BT019679-1|AAV38485.1| 346|Homo sapiens secreted frizzled-relat... 39 0.011
BC058911-1|AAH58911.1| 346|Homo sapiens secreted frizzled-relat... 39 0.011
BC047684-1|AAH47684.1| 346|Homo sapiens SFRP4 protein protein. 39 0.011
BC032828-1|AAH32828.1| 443|Homo sapiens SFRP4 protein protein. 39 0.011
CR541731-1|CAG46532.1| 346|Homo sapiens SFRP4 protein. 38 0.024
AF026692-1|AAC04617.1| 346|Homo sapiens frpHE protein. 37 0.032
AY005130-1|AAF89088.1| 666|Homo sapiens frizzled-3 protein. 32 1.2
AJ272427-1|CAB89114.1| 666|Homo sapiens frizzled homolog 3 prot... 32 1.2
AB065574-1|BAC05807.1| 337|Homo sapiens seven transmembrane hel... 32 1.2
AB039723-1|BAA94968.1| 666|Homo sapiens WNT receptor frizzled-3... 32 1.2
>U84401-1|AAB41788.1| 787|Homo sapiens smoothened protein.
Length = 787
Score = 78.2 bits (184), Expect = 1e-14
Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +2
Query: 194 LDSCVRGARCEQLNAT-CLGSKLPYDKTSIHLTFYYN-QNQIQNQLELYRELINVPNCWA 367
L C R A CE L CLGS LPY TS L + Q + +L L+ L N P CWA
Sbjct: 61 LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA 120
Query: 368 VIQPLLCATFMPKCENILGRDMVYLPS 448
VIQPLLCA +MPKCEN D V LPS
Sbjct: 121 VIQPLLCAVYMPKCEN----DRVELPS 143
>BC009989-1|AAH09989.1| 787|Homo sapiens smoothened homolog
(Drosophila) protein.
Length = 787
Score = 78.2 bits (184), Expect = 1e-14
Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +2
Query: 194 LDSCVRGARCEQLNAT-CLGSKLPYDKTSIHLTFYYN-QNQIQNQLELYRELINVPNCWA 367
L C R A CE L CLGS LPY TS L + Q + +L L+ L N P CWA
Sbjct: 61 LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA 120
Query: 368 VIQPLLCATFMPKCENILGRDMVYLPS 448
VIQPLLCA +MPKCEN D V LPS
Sbjct: 121 VIQPLLCAVYMPKCEN----DRVELPS 143
>AF120103-1|AAF31757.1| 787|Homo sapiens Gx protein protein.
Length = 787
Score = 78.2 bits (184), Expect = 1e-14
Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +2
Query: 194 LDSCVRGARCEQLNAT-CLGSKLPYDKTSIHLTFYYN-QNQIQNQLELYRELINVPNCWA 367
L C R A CE L CLGS LPY TS L + Q + +L L+ L N P CWA
Sbjct: 61 LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA 120
Query: 368 VIQPLLCATFMPKCENILGRDMVYLPS 448
VIQPLLCA +MPKCEN D V LPS
Sbjct: 121 VIQPLLCAVYMPKCEN----DRVELPS 143
>AF114821-1|AAD17202.1| 787|Homo sapiens smoothened protein.
Length = 787
Score = 78.2 bits (184), Expect = 1e-14
Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +2
Query: 194 LDSCVRGARCEQLNAT-CLGSKLPYDKTSIHLTFYYN-QNQIQNQLELYRELINVPNCWA 367
L C R A CE L CLGS LPY TS L + Q + +L L+ L N P CWA
Sbjct: 61 LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA 120
Query: 368 VIQPLLCATFMPKCENILGRDMVYLPS 448
VIQPLLCA +MPKCEN D V LPS
Sbjct: 121 VIQPLLCAVYMPKCEN----DRVELPS 143
>AF071494-1|AAC24863.1| 787|Homo sapiens Gx protein protein.
Length = 787
Score = 78.2 bits (184), Expect = 1e-14
Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Frame = +2
Query: 194 LDSCVRGARCEQLNAT-CLGSKLPYDKTSIHLTFYYN-QNQIQNQLELYRELINVPNCWA 367
L C R A CE L CLGS LPY TS L + Q + +L L+ L N P CWA
Sbjct: 61 LSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWA 120
Query: 368 VIQPLLCATFMPKCENILGRDMVYLPS 448
VIQPLLCA +MPKCEN D V LPS
Sbjct: 121 VIQPLLCAVYMPKCEN----DRVELPS 143
>DQ420628-1|ABD83351.1| 346|Homo sapiens secreted frizzled-related
protein 4 protein.
Length = 346
Score = 38.7 bits (86), Expect = 0.011
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 76 FLCAMYAPIC 85
>CR541755-1|CAG46555.1| 346|Homo sapiens SFRP4 protein.
Length = 346
Score = 38.7 bits (86), Expect = 0.011
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 76 FLCAMYAPIC 85
>BT019679-1|AAV38485.1| 346|Homo sapiens secreted frizzled-related
protein 4 protein.
Length = 346
Score = 38.7 bits (86), Expect = 0.011
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 76 FLCAMYAPIC 85
>BC058911-1|AAH58911.1| 346|Homo sapiens secreted frizzled-related
protein 4 protein.
Length = 346
Score = 38.7 bits (86), Expect = 0.011
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 76 FLCAMYAPIC 85
>BC047684-1|AAH47684.1| 346|Homo sapiens SFRP4 protein protein.
Length = 346
Score = 38.7 bits (86), Expect = 0.011
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 76 FLCAMYAPIC 85
>BC032828-1|AAH32828.1| 443|Homo sapiens SFRP4 protein protein.
Length = 443
Score = 38.7 bits (86), Expect = 0.011
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 116 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 172
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 173 FLCAMYAPIC 182
>CR541731-1|CAG46532.1| 346|Homo sapiens SFRP4 protein.
Length = 346
Score = 37.5 bits (83), Expect = 0.024
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
+RGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 MRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
LCA + P C
Sbjct: 76 FLCAMYAPIC 85
>AF026692-1|AAC04617.1| 346|Homo sapiens frpHE protein.
Length = 346
Score = 37.1 bits (82), Expect = 0.032
Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Frame = +2
Query: 206 VRGARCEQLNATCLGSKLPYDKTSI--HLTFYYNQNQIQNQLELYRELINVPNCWAVIQP 379
VRGA CE + + +P++ T + HL +N I +E Y EL++V NC AV++
Sbjct: 19 VRGAPCEAVRIP-MCRHMPWNITRMPNHLHHSTQENAIL-AIEQYEELVDV-NCSAVLRF 75
Query: 380 LLCATFMPKC 409
CA + P C
Sbjct: 76 FFCAMYAPIC 85
>AY005130-1|AAF89088.1| 666|Homo sapiens frizzled-3 protein.
Length = 666
Score = 31.9 bits (69), Expect = 1.2
Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 257 LPYDKTSI-HLTFYYNQNQIQNQLELYRELINVPNCWAVIQPLLCATFMPKC 409
LPY+ T + +L +Y+Q +E + ++N+ +C +P LCA + P C
Sbjct: 39 LPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNL-DCSRDFRPFLCALYAPIC 89
>AJ272427-1|CAB89114.1| 666|Homo sapiens frizzled homolog 3
protein.
Length = 666
Score = 31.9 bits (69), Expect = 1.2
Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 257 LPYDKTSI-HLTFYYNQNQIQNQLELYRELINVPNCWAVIQPLLCATFMPKC 409
LPY+ T + +L +Y+Q +E + ++N+ +C +P LCA + P C
Sbjct: 39 LPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNL-DCSRDFRPFLCALYAPIC 89
>AB065574-1|BAC05807.1| 337|Homo sapiens seven transmembrane helix
receptor protein.
Length = 337
Score = 31.9 bits (69), Expect = 1.2
Identities = 14/23 (60%), Positives = 16/23 (69%)
Frame = -2
Query: 414 FSHFGINVAQSKGCITAQQFGTF 346
FSH G+ A S+G ITAQQ G F
Sbjct: 86 FSHLGMYTAHSRGWITAQQRGAF 108
>AB039723-1|BAA94968.1| 666|Homo sapiens WNT receptor frizzled-3
protein.
Length = 666
Score = 31.9 bits (69), Expect = 1.2
Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 257 LPYDKTSI-HLTFYYNQNQIQNQLELYRELINVPNCWAVIQPLLCATFMPKC 409
LPY+ T + +L +Y+Q +E + ++N+ +C +P LCA + P C
Sbjct: 39 LPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNL-DCSRDFRPFLCALYAPIC 89
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,078,303
Number of Sequences: 237096
Number of extensions: 1460331
Number of successful extensions: 2759
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 2706
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2754
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 4327667848
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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