Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0008_O08
(424 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, t... 126 3e-29
AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1... 126 3e-29
AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein... 126 3e-29
AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease ... 126 3e-29
AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, t... 126 3e-29
AF123046-1|AAF28875.1| 190|Homo sapiens Niemann-Pick C1 disease... 118 1e-26
BC117178-1|AAI17179.1| 1332|Homo sapiens NPC1L1 protein protein. 97 3e-20
AY515256-1|AAS56939.1| 1332|Homo sapiens NPC1L1 splice variant p... 97 3e-20
AY437865-1|AAR97886.1| 1332|Homo sapiens Niemann-Pick C1-like 1 ... 97 3e-20
AF192522-1|AAF20396.1| 1359|Homo sapiens Niemann-Pick C1-like pr... 93 3e-19
Y15061-1|CAA75345.1| 378|Homo sapiens GalT4 protein protein. 33 0.40
CR457093-1|CAG33374.1| 378|Homo sapiens B3GALT4 protein. 33 0.40
BC032574-1|AAH32574.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta... 33 0.40
AL844527-18|CAI41849.1| 378|Homo sapiens UDP-Gal:betaGlcNAc bet... 33 0.40
AL662827-1|CAI17515.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta... 33 0.40
AL662820-1|CAI18111.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta... 33 0.40
AL031228-1|CAA20230.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta... 33 0.40
AB026730-1|BAA88988.1| 378|Homo sapiens beta-1,3-galactosyltran... 33 0.40
AY438664-1|AAR05447.1| 1203|Homo sapiens patched homolog 2 (Dros... 30 3.7
AY359016-1|AAQ89375.1| 1203|Homo sapiens Patched 2 protein. 30 3.7
AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein. 30 3.7
AL592166-5|CAI13000.1| 1203|Homo sapiens patched homolog 2 (Dros... 30 3.7
AL136380-1|CAI23127.1| 1203|Homo sapiens patched homolog 2 (Dros... 30 3.7
AF119569-1|AAD17260.1| 1146|Homo sapiens patched 2 protein. 30 3.7
AF091501-1|AAC79847.1| 1203|Homo sapiens receptor protein patche... 30 3.7
AF087651-1|AAD25953.1| 1203|Homo sapiens patched 2 protein. 30 3.7
AJ235657-1|CAA15316.1| 135|Homo sapiens immunoglobulin heavy ch... 29 4.9
X77922-1|CAA54891.1| 356|Homo sapiens GD3 synthase protein. 29 6.5
L43494-1|AAC37586.1| 356|Homo sapiens ganglioside-specific alph... 29 6.5
L32867-1|AAA62366.1| 341|Homo sapiens alpha 2,8-sialyltransfera... 29 6.5
D26360-1|BAA05391.1| 341|Homo sapiens alpha 2,8-sialyltransfera... 29 6.5
BC126162-1|AAI26163.1| 356|Homo sapiens ST8 alpha-N-acetyl-neur... 29 6.5
BC117285-1|AAI17286.1| 356|Homo sapiens ST8 alpha-N-acetyl-neur... 29 6.5
AB071199-1|BAB78593.1| 75|Homo sapiens Bim-beta3 protein. 29 6.5
BC111540-1|AAI11541.1| 138|Homo sapiens chromosome 21 open read... 29 8.5
BC111539-1|AAI11540.1| 138|Homo sapiens C21orf123 protein protein. 29 8.5
BC045535-1|AAH45535.1| 733|Homo sapiens C1orf25 protein protein. 29 8.5
BC039738-1|AAH39738.1| 574|Homo sapiens Similar to chromosome 1... 29 8.5
AL136133-1|CAI17938.1| 733|Homo sapiens chromosome 1 open readi... 29 8.5
AL109865-1|CAI17847.1| 733|Homo sapiens chromosome 1 open readi... 29 8.5
AK131460-1|BAD18605.1| 390|Homo sapiens protein ( Homo sapiens ... 29 8.5
AK096071-1|BAC04694.1| 138|Homo sapiens protein ( Homo sapiens ... 29 8.5
AK074993-1|BAC11341.1| 733|Homo sapiens protein ( Homo sapiens ... 29 8.5
AK074936-1|BAC11302.1| 733|Homo sapiens protein ( Homo sapiens ... 29 8.5
AF288399-1|AAG60618.1| 733|Homo sapiens C1orf25 protein. 29 8.5
>BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, type
C1 protein.
Length = 1278
Score = 126 bits (304), Expect = 3e-29
Identities = 63/128 (49%), Positives = 91/128 (71%)
Frame = +3
Query: 39 KVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFY 218
+V AT + YH+VL+TS D+ A++ ARL+A+N+TET+ +N G+ + VFPYSVFY
Sbjct: 1032 RVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAY--RVFPYSVFY 1085
Query: 219 VFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWW 398
VFYEQYLT+ DT+ ++G+S+ +IF+VT VL+G +L+SA N+ G+M+ W
Sbjct: 1086 VFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLW 1145
Query: 399 GISLNAVS 422
GISLNAVS
Sbjct: 1146 GISLNAVS 1153
>AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1
protein protein.
Length = 1278
Score = 126 bits (304), Expect = 3e-29
Identities = 63/128 (49%), Positives = 91/128 (71%)
Frame = +3
Query: 39 KVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFY 218
+V AT + YH+VL+TS D+ A++ ARL+A+N+TET+ +N G+ + VFPYSVFY
Sbjct: 1032 RVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAY--RVFPYSVFY 1085
Query: 219 VFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWW 398
VFYEQYLT+ DT+ ++G+S+ +IF+VT VL+G +L+SA N+ G+M+ W
Sbjct: 1086 VFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLW 1145
Query: 399 GISLNAVS 422
GISLNAVS
Sbjct: 1146 GISLNAVS 1153
>AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein
protein.
Length = 1278
Score = 126 bits (304), Expect = 3e-29
Identities = 63/128 (49%), Positives = 91/128 (71%)
Frame = +3
Query: 39 KVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFY 218
+V AT + YH+VL+TS D+ A++ ARL+A+N+TET+ +N G+ + VFPYSVFY
Sbjct: 1032 RVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAY--RVFPYSVFY 1085
Query: 219 VFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWW 398
VFYEQYLT+ DT+ ++G+S+ +IF+VT VL+G +L+SA N+ G+M+ W
Sbjct: 1086 VFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLW 1145
Query: 399 GISLNAVS 422
GISLNAVS
Sbjct: 1146 GISLNAVS 1153
>AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease
protein protein.
Length = 1278
Score = 126 bits (304), Expect = 3e-29
Identities = 63/128 (49%), Positives = 91/128 (71%)
Frame = +3
Query: 39 KVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFY 218
+V AT + YH+VL+TS D+ A++ ARL+A+N+TET+ +N G+ + VFPYSVFY
Sbjct: 1032 RVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAY--RVFPYSVFY 1085
Query: 219 VFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWW 398
VFYEQYLT+ DT+ ++G+S+ +IF+VT VL+G +L+SA N+ G+M+ W
Sbjct: 1086 VFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLW 1145
Query: 399 GISLNAVS 422
GISLNAVS
Sbjct: 1146 GISLNAVS 1153
>AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, type
C1 variant protein.
Length = 1289
Score = 126 bits (304), Expect = 3e-29
Identities = 63/128 (49%), Positives = 91/128 (71%)
Frame = +3
Query: 39 KVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFY 218
+V AT + YH+VL+TS D+ A++ ARL+A+N+TET+ +N G+ + VFPYSVFY
Sbjct: 1043 RVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN----GSAY--RVFPYSVFY 1096
Query: 219 VFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWW 398
VFYEQYLT+ DT+ ++G+S+ +IF+VT VL+G +L+SA N+ G+M+ W
Sbjct: 1097 VFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLW 1156
Query: 399 GISLNAVS 422
GISLNAVS
Sbjct: 1157 GISLNAVS 1164
>AF123046-1|AAF28875.1| 190|Homo sapiens Niemann-Pick C1 disease
protein protein.
Length = 190
Score = 118 bits (283), Expect = 1e-26
Identities = 59/118 (50%), Positives = 85/118 (72%)
Frame = +3
Query: 69 HSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
H+VL+TS D+ A++ ARL+A+N+TET+ +N G+ + VFPYSVFYVFYEQYLT+
Sbjct: 1 HTVLQTSADFIDALKKARLIASNVTETMGIN----GSAY--RVFPYSVFYVFYEQYLTII 54
Query: 249 PDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWWGISLNAVS 422
DT+ ++G+S+ +IF+VT VL+G +L+SA N+ G+M+ WGISLNAVS
Sbjct: 55 DDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVS 112
>BC117178-1|AAI17179.1| 1332|Homo sapiens NPC1L1 protein protein.
Length = 1332
Score = 96.7 bits (230), Expect = 3e-20
Identities = 56/140 (40%), Positives = 77/140 (55%)
Frame = +3
Query: 3 TRVNYITNGTLAKVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNN 182
T VN ++G +V A+ + YH LK S DY A+RAAR +AAN+T L K G +
Sbjct: 1034 TSVNLTSDG---QVLASRFMAYHKPLKNSQDYTEALRAARELAANITADLR---KVPGTD 1087
Query: 183 FTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXX 362
VFPY++ VFYEQYLT+ P+ L + + ++ F V+ +L+G DL S
Sbjct: 1088 PAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVM 1147
Query: 363 XXXNLGGLMYWWGISLNAVS 422
+ G M WGIS NAVS
Sbjct: 1148 ILVDTVGFMALWGISYNAVS 1167
>AY515256-1|AAS56939.1| 1332|Homo sapiens NPC1L1 splice variant
protein.
Length = 1332
Score = 96.7 bits (230), Expect = 3e-20
Identities = 56/140 (40%), Positives = 77/140 (55%)
Frame = +3
Query: 3 TRVNYITNGTLAKVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNN 182
T VN ++G +V A+ + YH LK S DY A+RAAR +AAN+T L K G +
Sbjct: 1034 TSVNLTSDG---QVLASRFMAYHKPLKNSQDYTEALRAARELAANITADLR---KVPGTD 1087
Query: 183 FTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXX 362
VFPY++ VFYEQYLT+ P+ L + + ++ F V+ +L+G DL S
Sbjct: 1088 PAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVM 1147
Query: 363 XXXNLGGLMYWWGISLNAVS 422
+ G M WGIS NAVS
Sbjct: 1148 ILVDTVGFMALWGISYNAVS 1167
>AY437865-1|AAR97886.1| 1332|Homo sapiens Niemann-Pick C1-like 1
protein.
Length = 1332
Score = 96.7 bits (230), Expect = 3e-20
Identities = 56/140 (40%), Positives = 77/140 (55%)
Frame = +3
Query: 3 TRVNYITNGTLAKVTATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNN 182
T VN ++G +V A+ + YH LK S DY A+RAAR +AAN+T L K G +
Sbjct: 1034 TSVNLTSDG---QVLASRFMAYHKPLKNSQDYTEALRAARELAANITADLR---KVPGTD 1087
Query: 183 FTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXX 362
VFPY++ VFYEQYLT+ P+ L + + ++ F V+ +L+G DL S
Sbjct: 1088 PAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVM 1147
Query: 363 XXXNLGGLMYWWGISLNAVS 422
+ G M WGIS NAVS
Sbjct: 1148 ILVDTVGFMALWGISYNAVS 1167
>AF192522-1|AAF20396.1| 1359|Homo sapiens Niemann-Pick C1-like protein
1 protein.
Length = 1359
Score = 93.5 bits (222), Expect = 3e-19
Identities = 51/126 (40%), Positives = 70/126 (55%)
Frame = +3
Query: 45 TATSYQVYHSVLKTSHDYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSVFYVF 224
+A+ + YH LK S DY A+RAAR +AAN+T L K G + VFPY++ VF
Sbjct: 1072 SASRFMAYHKPLKNSQDYTEALRAARELAANITADLR---KVPGTDPAFEVFPYTITNVF 1128
Query: 225 YEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWWGI 404
YEQYLT+ P+ L + + ++ F V+ +L+G DL S + G M WGI
Sbjct: 1129 YEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGI 1188
Query: 405 SLNAVS 422
S NAVS
Sbjct: 1189 SYNAVS 1194
>Y15061-1|CAA75345.1| 378|Homo sapiens GalT4 protein protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>CR457093-1|CAG33374.1| 378|Homo sapiens B3GALT4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>BC032574-1|AAH32574.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta
1,3-galactosyltransferase, polypeptide 4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>AL844527-18|CAI41849.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta
1,3-galactosyltransferase, polypeptide 4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>AL662827-1|CAI17515.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta
1,3-galactosyltransferase, polypeptide 4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>AL662820-1|CAI18111.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta
1,3-galactosyltransferase, polypeptide 4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>AL031228-1|CAA20230.1| 378|Homo sapiens UDP-Gal:betaGlcNAc beta
1,3-galactosyltransferase, polypeptide 4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>AB026730-1|BAA88988.1| 378|Homo sapiens
beta-1,3-galactosyltransferase-4 protein.
Length = 378
Score = 33.1 bits (72), Expect = 0.40
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Frame = +2
Query: 26 RYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSARGGQPHR--DPQHELEGDGKQ-LHSER 196
RY + D D+ VP+ + L+L R R GQ R +PQ E E +G Q LHSE
Sbjct: 169 RYVLKTDDDVYVNVPELVSE---LVL----RGGRWGQWERSTEPQREAEQEGGQVLHSEE 221
Query: 197 VPLFSVLRV 223
VPL + RV
Sbjct: 222 VPLLYLGRV 230
>AY438664-1|AAR05447.1| 1203|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 1203
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AY359016-1|AAQ89375.1| 1203|Homo sapiens Patched 2 protein.
Length = 1203
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein.
Length = 1211
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AL592166-5|CAI13000.1| 1203|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 1203
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AL136380-1|CAI23127.1| 1203|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 1203
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AF119569-1|AAD17260.1| 1146|Homo sapiens patched 2 protein.
Length = 1146
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AF091501-1|AAC79847.1| 1203|Homo sapiens receptor protein patched 2
protein.
Length = 1203
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AF087651-1|AAD25953.1| 1203|Homo sapiens patched 2 protein.
Length = 1203
Score = 29.9 bits (64), Expect = 3.7
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 189 VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXX 368
V+ +P ++F+EQYL + L ++ I ++ F+V +L+ + ++A
Sbjct: 942 VHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLL-LNPWTAGLIVLVLAMMT 1000
Query: 369 XNLGGLMYWWGISLNAV 419
L G+M + GI L+A+
Sbjct: 1001 VELFGIMGFLGIKLSAI 1017
>AJ235657-1|CAA15316.1| 135|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 135
Score = 29.5 bits (63), Expect = 4.9
Identities = 13/32 (40%), Positives = 16/32 (50%)
Frame = -2
Query: 135 WPPRAERLAWQSSSRGWSSARCGTPGMRSPSP 40
WPPR ++ R S + G G RSPSP
Sbjct: 104 WPPRTQQFIIVRERRHLSVSTSGAKGPRSPSP 135
>X77922-1|CAA54891.1| 356|Homo sapiens GD3 synthase protein.
Length = 356
Score = 29.1 bits (62), Expect = 6.5
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +3
Query: 147 TLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
++NM+ + +++ NV P+S F+ E++L +W
Sbjct: 299 SVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLW 332
>L43494-1|AAC37586.1| 356|Homo sapiens ganglioside-specific
alpha-2, 8-polysialyltransferase protein.
Length = 356
Score = 29.1 bits (62), Expect = 6.5
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +3
Query: 147 TLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
++NM+ + +++ NV P+S F+ E++L +W
Sbjct: 299 SVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLW 332
>L32867-1|AAA62366.1| 341|Homo sapiens alpha 2,8-sialyltransferase
protein.
Length = 341
Score = 29.1 bits (62), Expect = 6.5
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +3
Query: 147 TLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
++NM+ + +++ NV P+S F+ E++L +W
Sbjct: 284 SVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLW 317
>D26360-1|BAA05391.1| 341|Homo sapiens alpha 2,8-sialyltransferase
protein.
Length = 341
Score = 29.1 bits (62), Expect = 6.5
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +3
Query: 147 TLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
++NM+ + +++ NV P+S F+ E++L +W
Sbjct: 284 SVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLW 317
>BC126162-1|AAI26163.1| 356|Homo sapiens ST8
alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
protein.
Length = 356
Score = 29.1 bits (62), Expect = 6.5
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +3
Query: 147 TLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
++NM+ + +++ NV P+S F+ E++L +W
Sbjct: 299 SVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLW 332
>BC117285-1|AAI17286.1| 356|Homo sapiens ST8
alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
protein.
Length = 356
Score = 29.1 bits (62), Expect = 6.5
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +3
Query: 147 TLNMNLKETGNNFTVNVFPYSVFYVFYEQYLTMW 248
++NM+ + +++ NV P+S F+ E++L +W
Sbjct: 299 SVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLW 332
>AB071199-1|BAB78593.1| 75|Homo sapiens Bim-beta3 protein.
Length = 75
Score = 29.1 bits (62), Expect = 6.5
Identities = 13/34 (38%), Positives = 17/34 (50%)
Frame = +2
Query: 23 QRYPGEGDGDLIPGVPQRAEDQPRLLLCHASRSA 124
Q P E L PG P + +P++ LCH SA
Sbjct: 18 QLQPAERPPQLRPGAPTSLQTEPQVSLCHPGWSA 51
>BC111540-1|AAI11541.1| 138|Homo sapiens chromosome 21 open
reading frame 123 protein.
Length = 138
Score = 28.7 bits (61), Expect = 8.5
Identities = 9/20 (45%), Positives = 13/20 (65%)
Frame = -2
Query: 87 WSSARCGTPGMRSPSPSPGY 28
W ARC PG + +P+PG+
Sbjct: 10 WHGARCVRPGSHAKAPAPGF 29
>BC111539-1|AAI11540.1| 138|Homo sapiens C21orf123 protein
protein.
Length = 138
Score = 28.7 bits (61), Expect = 8.5
Identities = 9/20 (45%), Positives = 13/20 (65%)
Frame = -2
Query: 87 WSSARCGTPGMRSPSPSPGY 28
W ARC PG + +P+PG+
Sbjct: 10 WHGARCVRPGSHAKAPAPGF 29
>BC045535-1|AAH45535.1| 733|Homo sapiens C1orf25 protein protein.
Length = 733
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
>BC039738-1|AAH39738.1| 574|Homo sapiens Similar to chromosome 1
open reading frame 25 protein.
Length = 574
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
>AL136133-1|CAI17938.1| 733|Homo sapiens chromosome 1 open reading
frame 25 protein.
Length = 733
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
>AL109865-1|CAI17847.1| 733|Homo sapiens chromosome 1 open reading
frame 25 protein.
Length = 733
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
>AK131460-1|BAD18605.1| 390|Homo sapiens protein ( Homo sapiens
cDNA FLJ16620 fis, clone TESTI4014801. ).
Length = 390
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 9 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 54
>AK096071-1|BAC04694.1| 138|Homo sapiens protein ( Homo sapiens
cDNA FLJ38752 fis, clone KIDNE2012613. ).
Length = 138
Score = 28.7 bits (61), Expect = 8.5
Identities = 9/20 (45%), Positives = 13/20 (65%)
Frame = -2
Query: 87 WSSARCGTPGMRSPSPSPGY 28
W ARC PG + +P+PG+
Sbjct: 10 WHGARCVRPGSHAKAPAPGF 29
>AK074993-1|BAC11341.1| 733|Homo sapiens protein ( Homo sapiens
cDNA FLJ90512 fis, clone NT2RP3004345, weakly similar to
N2,N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE PRECURSOR
(EC ).
Length = 733
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
>AK074936-1|BAC11302.1| 733|Homo sapiens protein ( Homo sapiens
cDNA FLJ90455 fis, clone NT2RP3001592, weakly similar to
N2,N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE PRECURSOR
(EC ).
Length = 733
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
>AF288399-1|AAG60618.1| 733|Homo sapiens C1orf25 protein.
Length = 733
Score = 28.7 bits (61), Expect = 8.5
Identities = 14/46 (30%), Positives = 20/46 (43%)
Frame = -3
Query: 251 RPHSQVLFVEHVKH*IGEHVHCEVVSRLLQVHVEGLGEVGRHEPSG 114
RP + E + +G H HC + S + + LG V RH G
Sbjct: 165 RPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKG 210
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 57,528,675
Number of Sequences: 237096
Number of extensions: 1148491
Number of successful extensions: 4133
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 3735
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4118
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3259265358
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -