Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0008_O08
(424 letters)
Database: celegans
27,780 sequences; 12,740,198 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U53340-7|AAA96211.2| 1383|Caenorhabditis elegans Npc1 (human nie... 58 3e-09
Z69884-4|CAA93751.2| 913|Caenorhabditis elegans Hypothetical pr... 44 3e-05
AC024746-6|AAT92059.1| 1361|Caenorhabditis elegans Patched famil... 42 2e-04
AC024746-5|AAT92058.1| 1358|Caenorhabditis elegans Patched famil... 42 2e-04
Z46812-1|CAA86843.1| 1405|Caenorhabditis elegans Hypothetical pr... 42 2e-04
U23176-2|AAC46717.2| 667|Caenorhabditis elegans Patched family ... 42 2e-04
L11247-2|AAK84521.1| 1274|Caenorhabditis elegans Npc1 (human nie... 41 3e-04
U80447-8|AAB37812.3| 900|Caenorhabditis elegans Patched related... 35 0.028
U88308-9|AAB42325.1| 933|Caenorhabditis elegans Patched related... 34 0.048
AL034393-26|CAI59121.1| 936|Caenorhabditis elegans Hypothetical... 31 0.34
AL132853-3|CAB60438.1| 859|Caenorhabditis elegans Hypothetical ... 30 0.59
Z68879-10|CAA93082.2| 473|Caenorhabditis elegans Hypothetical p... 29 1.0
U80842-1|AAB37946.2| 1000|Caenorhabditis elegans Guanylyl cyclas... 28 3.2
AL117202-2|CAB55092.1| 302|Caenorhabditis elegans Hypothetical ... 28 3.2
AF106584-2|AAC78222.2| 316|Caenorhabditis elegans Hypothetical ... 28 3.2
AF016681-14|AAB66169.1| 1119|Caenorhabditis elegans Guanylyl cyc... 28 3.2
Z35640-6|CAA84702.2| 1226|Caenorhabditis elegans Hypothetical pr... 27 7.3
Z35639-9|CAA84700.2| 1226|Caenorhabditis elegans Hypothetical pr... 27 7.3
AL021497-8|CAA16409.1| 334|Caenorhabditis elegans Hypothetical ... 27 7.3
Z81133-3|CAB03443.3| 527|Caenorhabditis elegans Hypothetical pr... 26 9.7
Z81058-11|CAH60760.1| 201|Caenorhabditis elegans Hypothetical p... 26 9.7
AL034393-25|CAI59120.1| 797|Caenorhabditis elegans Hypothetical... 26 9.7
AL034393-24|CAA22312.3| 833|Caenorhabditis elegans Hypothetical... 26 9.7
>U53340-7|AAA96211.2| 1383|Caenorhabditis elegans Npc1 (human niemann
pick c disease)related protein 1 protein.
Length = 1383
Score = 57.6 bits (133), Expect = 3e-09
Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Frame = +3
Query: 39 KVTATSYQVYHSVLKTSH--DYYSAMRAARLVAANLTETLNMNLKETGNNFTVNVFPYSV 212
++ A+ + +H L S+ D+ AM AR+V+ L +++ T +VF YS
Sbjct: 1065 RIQASQFMTFHKKLSISNSSDFIKAMDTARMVSRRLERSIDD---------TAHVFAYSK 1115
Query: 213 FYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMY 392
+ FYEQY T+ P + I+V+ +F + V +G D+ A ++ MY
Sbjct: 1116 IFPFYEQYSTIMPILTTQLFITVVGVFGIICVTLGIDVKGAACAVICQVSNYFHIVAFMY 1175
Query: 393 WWGISLNAVS 422
+ I +NA+S
Sbjct: 1176 IFNIPVNALS 1185
>Z69884-4|CAA93751.2| 913|Caenorhabditis elegans Hypothetical
protein F31F6.5 protein.
Length = 913
Score = 44.4 bits (100), Expect = 3e-05
Identities = 26/87 (29%), Positives = 47/87 (54%)
Frame = +3
Query: 162 LKETGNNFTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXX 341
L++ ++ NV Y + F +QYL + P T++++ IS+L + +V+F+L+ L S
Sbjct: 719 LRDIADHQPFNVVVYHEAFPFADQYLIILPATIQNVVISLLCMAVVSFLLVP-SLPSGFV 777
Query: 342 XXXXXXXXXXNLGGLMYWWGISLNAVS 422
+ G M WG++L+AVS
Sbjct: 778 IFVSIVSINIGVFGYMTLWGVNLDAVS 804
>AC024746-6|AAT92059.1| 1361|Caenorhabditis elegans Patched family
protein 3, isoform b protein.
Length = 1361
Score = 41.9 bits (94), Expect = 2e-04
Identities = 23/74 (31%), Positives = 39/74 (52%)
Frame = +3
Query: 201 PYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLG 380
P + + F+EQYLT+ + +++ I L++F V +LM F+ ++A LG
Sbjct: 1120 PSGIAFTFWEQYLTLRWNLFQAICIIALAVFCVISILM-FNPWAATLIMCIVVITTIELG 1178
Query: 381 GLMYWWGISLNAVS 422
G M GI +N +S
Sbjct: 1179 GFMGLMGIKMNPIS 1192
>AC024746-5|AAT92058.1| 1358|Caenorhabditis elegans Patched family
protein 3, isoform a protein.
Length = 1358
Score = 41.9 bits (94), Expect = 2e-04
Identities = 23/74 (31%), Positives = 39/74 (52%)
Frame = +3
Query: 201 PYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLG 380
P + + F+EQYLT+ + +++ I L++F V +LM F+ ++A LG
Sbjct: 1117 PSGIAFTFWEQYLTLRWNLFQAICIIALAVFCVISILM-FNPWAATLIMCIVVITTIELG 1175
Query: 381 GLMYWWGISLNAVS 422
G M GI +N +S
Sbjct: 1176 GFMGLMGIKMNPIS 1189
>Z46812-1|CAA86843.1| 1405|Caenorhabditis elegans Hypothetical protein
ZK675.1 protein.
Length = 1405
Score = 41.5 bits (93), Expect = 2e-04
Identities = 24/75 (32%), Positives = 39/75 (52%)
Frame = +3
Query: 198 FPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNL 377
FP + + F+EQYL + + ++++ I +S+F V VL+ F+ ++A L
Sbjct: 1161 FPQGIAFTFWEQYLFLTGNLMQAISIITISVFCVISVLL-FNPWAALMVVCILGIMTCEL 1219
Query: 378 GGLMYWWGISLNAVS 422
G M GI LN VS
Sbjct: 1220 AGFMGLVGIKLNPVS 1234
>U23176-2|AAC46717.2| 667|Caenorhabditis elegans Patched family
protein 2 protein.
Length = 667
Score = 41.5 bits (93), Expect = 2e-04
Identities = 24/75 (32%), Positives = 39/75 (52%)
Frame = +3
Query: 198 FPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNL 377
FP + + F+EQYL + + ++++ I +S+F V VL+ F+ ++A L
Sbjct: 532 FPQGIAFTFWEQYLFLTGNLMQAISIITISVFCVISVLL-FNPWAALMVVCILGIMTCEL 590
Query: 378 GGLMYWWGISLNAVS 422
G M GI LN VS
Sbjct: 591 AGFMGLVGIKLNPVS 605
>L11247-2|AAK84521.1| 1274|Caenorhabditis elegans Npc1 (human niemann
pick c disease)related protein 2 protein.
Length = 1274
Score = 41.1 bits (92), Expect = 3e-04
Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 3/141 (2%)
Frame = +3
Query: 9 VNYITNGTLAKVTATSYQVYHSVLKTSHDY--YSAMRAARLVAANLTETLNMNLKETGNN 182
+N NG K+ + + + L S Y A R A+ +A ++ L +
Sbjct: 1009 INLTRNG---KIQSAYFSTFFKKLNLSDSIQLYDAWRFAKYLADDIERELEIP------- 1058
Query: 183 FTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVL-MGFDLFSAXXXXXXXX 359
V V+ YS F+ +YEQYLT+ T+ ++ + VL + VT L + +L +
Sbjct: 1059 -GVKVYVYSTFFPYYEQYLTL-STTVYTLVVLVLFVAFVTISLFLRVNLAGSLVTVFVLL 1116
Query: 360 XXXXNLGGLMYWWGISLNAVS 422
+L MY GI++N VS
Sbjct: 1117 SSYLHLMEWMYLLGITVNVVS 1137
>U80447-8|AAB37812.3| 900|Caenorhabditis elegans Patched related
family protein 10 protein.
Length = 900
Score = 34.7 bits (76), Expect = 0.028
Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Frame = +3
Query: 141 TETLNMNLKETGNNFT-VNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMG 317
TE N +E + F NV Y ++F +QY + P+T++ + ++V + +++ +L+
Sbjct: 689 TEATN-TFREIASRFEQYNVTTYMPLWLFTDQYALVVPNTMQDIIVAVACMLVISALLIP 747
Query: 318 FDLFSAXXXXXXXXXXXXNLGGLMYWWGISLNAVS 422
+ S L G M W ++L+A+S
Sbjct: 748 QPVCSFWVAVTIGSIDLGVL-GFMTLWNVNLDAIS 781
>U88308-9|AAB42325.1| 933|Caenorhabditis elegans Patched related
family protein 2 protein.
Length = 933
Score = 33.9 bits (74), Expect = 0.048
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 192 NVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXX 371
NV + ++F +QY+ + P+T++++ I++L + IV VL +
Sbjct: 685 NVTTFMPIWMFTDQYIIIIPNTVQNIIIALL-VMIVIAVLFIPQPMCSLWVALACASIDF 743
Query: 372 NLGGLMYWWGISLNAVS 422
+ G M WG++L+A+S
Sbjct: 744 GVIGYMTLWGVNLDAIS 760
>AL034393-26|CAI59121.1| 936|Caenorhabditis elegans Hypothetical
protein Y18D10A.7c protein.
Length = 936
Score = 31.1 bits (67), Expect = 0.34
Identities = 19/77 (24%), Positives = 35/77 (45%)
Frame = +3
Query: 192 NVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXX 371
++ YS + ++Y MWP T++ + IS+ + V + + L S
Sbjct: 742 SIITYSPLWNIADEYDIMWPQTMQDIYISIAVMVPVALLFIPQPLCSVIIGLNIASIAFG 801
Query: 372 NLGGLMYWWGISLNAVS 422
+ G M + G+SL+A S
Sbjct: 802 VI-GTMSFLGVSLDATS 817
>AL132853-3|CAB60438.1| 859|Caenorhabditis elegans Hypothetical
protein Y80D3A.7 protein.
Length = 859
Score = 30.3 bits (65), Expect = 0.59
Identities = 22/86 (25%), Positives = 36/86 (41%)
Frame = +3
Query: 165 KETGNNFTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXX 344
K N V+PY+ F +Q + M D + + IS + +TF+L DL S
Sbjct: 625 KIAANYSEFEVYPYTERSNFVDQTVDM-VDNIWNTVISEVICMGLTFILFIPDLISIFSA 683
Query: 345 XXXXXXXXXNLGGLMYWWGISLNAVS 422
+ G + WG+ ++ VS
Sbjct: 684 VFALFSVNFGVFGFLSIWGVGMDPVS 709
>Z68879-10|CAA93082.2| 473|Caenorhabditis elegans Hypothetical
protein K08F4.2 protein.
Length = 473
Score = 29.5 bits (63), Expect = 1.0
Identities = 13/43 (30%), Positives = 25/43 (58%)
Frame = +2
Query: 65 VPQRAEDQPRLLLCHASRSARGGQPHRDPQHELEGDGKQLHSE 193
VP+ ++QP++ A+ GG+ + PQ + G G+Q+H +
Sbjct: 237 VPEPVQEQPKVQKTWANLVGGGGKS-QPPQQQSYGQGQQIHQQ 278
>U80842-1|AAB37946.2| 1000|Caenorhabditis elegans Guanylyl cyclase
protein 15 protein.
Length = 1000
Score = 27.9 bits (59), Expect = 3.2
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = +3
Query: 54 SYQVYHSVLKTSHDYYSAMRAARLVAANLTETL 152
S Q+Y+ +SH+ YS ARL ++L T+
Sbjct: 244 SMQIYYHFSSSSHNSYSLFPCARLAQSSLLNTV 276
>AL117202-2|CAB55092.1| 302|Caenorhabditis elegans Hypothetical
protein Y47D3A.2 protein.
Length = 302
Score = 27.9 bits (59), Expect = 3.2
Identities = 11/21 (52%), Positives = 14/21 (66%)
Frame = +3
Query: 144 ETLNMNLKETGNNFTVNVFPY 206
ET M LKET N F +++ PY
Sbjct: 271 ETFTMTLKETVNEFIIDMSPY 291
>AF106584-2|AAC78222.2| 316|Caenorhabditis elegans Hypothetical
protein F54A5.3a protein.
Length = 316
Score = 27.9 bits (59), Expect = 3.2
Identities = 11/41 (26%), Positives = 20/41 (48%)
Frame = -1
Query: 358 VIVTTTTRAEKRSNPIRTNVTMNMDSTDIPIDFNVSGHIVK 236
V T A + NP+ + V + + P+D N+S ++K
Sbjct: 52 VAATVGVTAAREINPVVSRVIGEVKKENFPVDINISSKMIK 92
>AF016681-14|AAB66169.1| 1119|Caenorhabditis elegans Guanylyl
cyclase protein 21 protein.
Length = 1119
Score = 27.9 bits (59), Expect = 3.2
Identities = 12/33 (36%), Positives = 19/33 (57%)
Frame = +3
Query: 54 SYQVYHSVLKTSHDYYSAMRAARLVAANLTETL 152
S Q+Y+ +SH+ YS ARL ++L T+
Sbjct: 305 SIQIYYHFSSSSHNSYSLFPCARLAQSSLLNTV 337
>Z35640-6|CAA84702.2| 1226|Caenorhabditis elegans Hypothetical protein
F43D9.1 protein.
Length = 1226
Score = 26.6 bits (56), Expect = 7.3
Identities = 10/62 (16%), Positives = 30/62 (48%)
Frame = +3
Query: 237 LTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWWGISLNA 416
++++ + + G++++ +F V+ +L+G + + G Y+W + +N
Sbjct: 862 ISVFTSGMLAFGVAIVMLFFVSLLLLGQPALTVMLLITSIAVLGETV-GYAYFWSVPMNI 920
Query: 417 VS 422
V+
Sbjct: 921 VT 922
>Z35639-9|CAA84700.2| 1226|Caenorhabditis elegans Hypothetical protein
F43D9.1 protein.
Length = 1226
Score = 26.6 bits (56), Expect = 7.3
Identities = 10/62 (16%), Positives = 30/62 (48%)
Frame = +3
Query: 237 LTMWPDTLKSMGISVLSIFIVTFVLMGFDLFSAXXXXXXXXXXXXNLGGLMYWWGISLNA 416
++++ + + G++++ +F V+ +L+G + + G Y+W + +N
Sbjct: 862 ISVFTSGMLAFGVAIVMLFFVSLLLLGQPALTVMLLITSIAVLGETV-GYAYFWSVPMNI 920
Query: 417 VS 422
V+
Sbjct: 921 VT 922
>AL021497-8|CAA16409.1| 334|Caenorhabditis elegans Hypothetical
protein Y51A2D.12 protein.
Length = 334
Score = 26.6 bits (56), Expect = 7.3
Identities = 12/29 (41%), Positives = 16/29 (55%)
Frame = +3
Query: 153 NMNLKETGNNFTVNVFPYSVFYVFYEQYL 239
N+NL T N F +N+F F Y QY+
Sbjct: 81 NLNLNNTENWFPLNIFHTFHFEFAYTQYI 109
>Z81133-3|CAB03443.3| 527|Caenorhabditis elegans Hypothetical
protein T28B8.5 protein.
Length = 527
Score = 26.2 bits (55), Expect = 9.7
Identities = 14/45 (31%), Positives = 21/45 (46%)
Frame = +2
Query: 170 DGKQLHSERVPLFSVLRVLRTVLDYVAGYVEIDGDIGAIHIHSDV 304
DG S PL+ + V+RT D + E G I IH+ ++
Sbjct: 194 DGMYSSSRAGPLYGLRMVMRTDQDTYLPWTEASGVIIDIHMQDEI 238
>Z81058-11|CAH60760.1| 201|Caenorhabditis elegans Hypothetical
protein F11E6.11 protein.
Length = 201
Score = 26.2 bits (55), Expect = 9.7
Identities = 10/24 (41%), Positives = 16/24 (66%)
Frame = +3
Query: 234 YLTMWPDTLKSMGISVLSIFIVTF 305
YL +WP + S I +LSIF++ +
Sbjct: 159 YLVIWPTFVLSFLILLLSIFVIIY 182
>AL034393-25|CAI59120.1| 797|Caenorhabditis elegans Hypothetical
protein Y18D10A.7b protein.
Length = 797
Score = 26.2 bits (55), Expect = 9.7
Identities = 9/30 (30%), Positives = 18/30 (60%)
Frame = +3
Query: 192 NVFPYSVFYVFYEQYLTMWPDTLKSMGISV 281
++ YS + ++Y MWP T++ + IS+
Sbjct: 726 SIITYSPLWNIADEYDIMWPQTMQDIYISI 755
>AL034393-24|CAA22312.3| 833|Caenorhabditis elegans Hypothetical
protein Y18D10A.7a protein.
Length = 833
Score = 26.2 bits (55), Expect = 9.7
Identities = 9/30 (30%), Positives = 18/30 (60%)
Frame = +3
Query: 192 NVFPYSVFYVFYEQYLTMWPDTLKSMGISV 281
++ YS + ++Y MWP T++ + IS+
Sbjct: 742 SIITYSPLWNIADEYDIMWPQTMQDIYISI 771
Database: celegans
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 12,740,198
Number of sequences in database: 27,780
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 8,665,650
Number of Sequences: 27780
Number of extensions: 169136
Number of successful extensions: 631
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 577
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 631
length of database: 12,740,198
effective HSP length: 75
effective length of database: 10,656,698
effective search space used: 692685370
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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