Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0006_N04
(561 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U68567-1|AAC50812.1| 988|Homo sapiens lysosomal acid alpha-mann... 130 2e-30
U60899-1|AAC51362.1| 1010|Homo sapiens lysosomal alpha-mannosida... 130 2e-30
U60266-1|AAC34130.1| 1011|Homo sapiens lysosomal alpha-mannosida... 130 2e-30
U05572-1|AAB03816.1| 987|Homo sapiens alpha-mannosidase protein. 130 2e-30
BC000736-1|AAH00736.1| 1011|Homo sapiens mannosidase, alpha, cla... 130 2e-30
AB209921-1|BAD93158.1| 1007|Homo sapiens mannosidase, alpha, cla... 130 2e-30
U31520-1|AAC50302.1| 1144|Homo sapiens alpha mannosidase II prot... 62 1e-09
D63998-1|BAA10017.1| 1143|Homo sapiens golgi alpha-mannosidaseII... 62 1e-09
BC142696-1|AAI42697.1| 1143|Homo sapiens MAN2A1 protein protein. 62 1e-09
BC142656-1|AAI42657.1| 1143|Homo sapiens MAN2A1 protein protein. 62 1e-09
BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, cla... 61 2e-09
BC036836-1|AAH36836.1| 358|Homo sapiens MAN2B2 protein protein. 61 2e-09
BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, cla... 61 2e-09
AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein pr... 61 2e-09
AB023152-1|BAA76779.2| 952|Homo sapiens KIAA0935 protein protein. 61 2e-09
D55649-1|BAA09510.1| 1139|Homo sapiens alpha mannosidase II isoz... 53 8e-07
>U68567-1|AAC50812.1| 988|Homo sapiens lysosomal acid
alpha-mannosidase protein.
Length = 988
Score = 130 bits (315), Expect = 2e-30
Identities = 66/137 (48%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Frame = +2
Query: 134 EINWFVR-ILIDDGVGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEP 310
E+ W V I + D GK+V+ + T + G+FYTDSNGR+IL+R + RP W + EP
Sbjct: 688 ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 747
Query: 311 VAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALN 490
VAGNYYPV IYI + + + TVLTDR+ GG+SL +G ++LMVHRRLL DD GV E L
Sbjct: 748 VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 807
Query: 491 ETVLGQPLVAIGTHVII 541
E G G H+++
Sbjct: 808 EN--GSGAWVRGRHLVL 822
>U60899-1|AAC51362.1| 1010|Homo sapiens lysosomal alpha-mannosidase
protein.
Length = 1010
Score = 130 bits (315), Expect = 2e-30
Identities = 66/137 (48%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Frame = +2
Query: 134 EINWFVR-ILIDDGVGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEP 310
E+ W V I + D GK+V+ + T + G+FYTDSNGR+IL+R + RP W + EP
Sbjct: 710 ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 769
Query: 311 VAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALN 490
VAGNYYPV IYI + + + TVLTDR+ GG+SL +G ++LMVHRRLL DD GV E L
Sbjct: 770 VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 829
Query: 491 ETVLGQPLVAIGTHVII 541
E G G H+++
Sbjct: 830 EN--GSGAWVRGRHLVL 844
>U60266-1|AAC34130.1| 1011|Homo sapiens lysosomal alpha-mannosidase
protein.
Length = 1011
Score = 130 bits (315), Expect = 2e-30
Identities = 66/137 (48%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Frame = +2
Query: 134 EINWFVR-ILIDDGVGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEP 310
E+ W V I + D GK+V+ + T + G+FYTDSNGR+IL+R + RP W + EP
Sbjct: 711 ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 770
Query: 311 VAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALN 490
VAGNYYPV IYI + + + TVLTDR+ GG+SL +G ++LMVHRRLL DD GV E L
Sbjct: 771 VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 830
Query: 491 ETVLGQPLVAIGTHVII 541
E G G H+++
Sbjct: 831 EN--GSGAWVRGRHLVL 845
>U05572-1|AAB03816.1| 987|Homo sapiens alpha-mannosidase protein.
Length = 987
Score = 130 bits (315), Expect = 2e-30
Identities = 66/137 (48%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Frame = +2
Query: 134 EINWFVR-ILIDDGVGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEP 310
E+ W V I + D GK+V+ + T + G+FYTDSNGR+IL+R + RP W + EP
Sbjct: 687 ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 746
Query: 311 VAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALN 490
VAGNYYPV IYI + + + TVLTDR+ GG+SL +G ++LMVHRRLL DD GV E L
Sbjct: 747 VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 806
Query: 491 ETVLGQPLVAIGTHVII 541
E G G H+++
Sbjct: 807 EN--GSGAWVRGRHLVL 821
>BC000736-1|AAH00736.1| 1011|Homo sapiens mannosidase, alpha, class
2B, member 1 protein.
Length = 1011
Score = 130 bits (315), Expect = 2e-30
Identities = 66/137 (48%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Frame = +2
Query: 134 EINWFVR-ILIDDGVGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEP 310
E+ W V I + D GK+V+ + T + G+FYTDSNGR+IL+R + RP W + EP
Sbjct: 711 ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 770
Query: 311 VAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALN 490
VAGNYYPV IYI + + + TVLTDR+ GG+SL +G ++LMVHRRLL DD GV E L
Sbjct: 771 VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 830
Query: 491 ETVLGQPLVAIGTHVII 541
E G G H+++
Sbjct: 831 EN--GSGAWVRGRHLVL 845
>AB209921-1|BAD93158.1| 1007|Homo sapiens mannosidase, alpha, class
2B, member 1 precursor variant protein.
Length = 1007
Score = 130 bits (315), Expect = 2e-30
Identities = 66/137 (48%), Positives = 88/137 (64%), Gaps = 1/137 (0%)
Frame = +2
Query: 134 EINWFVR-ILIDDGVGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEP 310
E+ W V I + D GK+V+ + T + G+FYTDSNGR+IL+R + RP W + EP
Sbjct: 707 ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 766
Query: 311 VAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALN 490
VAGNYYPV IYI + + + TVLTDR+ GG+SL +G ++LMVHRRLL DD GV E L
Sbjct: 767 VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 826
Query: 491 ETVLGQPLVAIGTHVII 541
E G G H+++
Sbjct: 827 EN--GSGAWVRGRHLVL 841
>U31520-1|AAC50302.1| 1144|Homo sapiens alpha mannosidase II protein.
Length = 1144
Score = 62.1 bits (144), Expect = 1e-09
Identities = 35/116 (30%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +2
Query: 179 KDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEE-PVAGNYYPVVNEIYIE 355
+++ + +DI + +FYTD NG QI R+ TL + P+ N YP+ YI+
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNGYQIQPRM---------TLSKLPLQANVYPMTTMAYIQ 926
Query: 356 NDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALNETVLGQPLVAI 523
+ R T+L+ ++ G +SL G+I++++ RRL+ DD G+ + + + + L I
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRI 982
>D63998-1|BAA10017.1| 1143|Homo sapiens golgi alpha-mannosidaseII
protein.
Length = 1143
Score = 62.1 bits (144), Expect = 1e-09
Identities = 35/116 (30%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +2
Query: 179 KDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEE-PVAGNYYPVVNEIYIE 355
+++ + +DI + +FYTD NG QI R+ TL + P+ N YP+ YI+
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNGYQIQPRM---------TLSKLPLQANVYPMTTMAYIQ 926
Query: 356 NDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALNETVLGQPLVAI 523
+ R T+L+ ++ G +SL G+I++++ RRL+ DD G+ + + + + L I
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRI 982
>BC142696-1|AAI42697.1| 1143|Homo sapiens MAN2A1 protein protein.
Length = 1143
Score = 62.1 bits (144), Expect = 1e-09
Identities = 35/116 (30%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +2
Query: 179 KDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEE-PVAGNYYPVVNEIYIE 355
+++ + +DI + +FYTD NG QI R+ TL + P+ N YP+ YI+
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNGYQIQPRM---------TLSKLPLQANVYPMTTMAYIQ 926
Query: 356 NDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALNETVLGQPLVAI 523
+ R T+L+ ++ G +SL G+I++++ RRL+ DD G+ + + + + L I
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRI 982
>BC142656-1|AAI42657.1| 1143|Homo sapiens MAN2A1 protein protein.
Length = 1143
Score = 62.1 bits (144), Expect = 1e-09
Identities = 35/116 (30%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +2
Query: 179 KDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEE-PVAGNYYPVVNEIYIE 355
+++ + +DI + +FYTD NG QI R+ TL + P+ N YP+ YI+
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNGYQIQPRM---------TLSKLPLQANVYPMTTMAYIQ 926
Query: 356 NDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEALNETVLGQPLVAI 523
+ R T+L+ ++ G +SL G+I++++ RRL+ DD G+ + + + + L I
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRI 982
>BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/117 (29%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 173 VGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEPVAGNYYPVVNEIYI 352
+ ++ VL T++ + Y+D+NG Q + +RP + + +A NYYP+V ++
Sbjct: 711 LNREAVLRTSTNLNSQQVIYSDNNGYQ-----MQRRPYVSY-VNNSIARNYYPMVQSAFM 764
Query: 353 ENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLH--DDAFGVGEALNETVLGQPLV 517
E+ R +L++RA G +S G++++M+HRRL + D G LN+T + P++
Sbjct: 765 EDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVL 821
>BC036836-1|AAH36836.1| 358|Homo sapiens MAN2B2 protein protein.
Length = 358
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/117 (29%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 173 VGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEPVAGNYYPVVNEIYI 352
+ ++ VL T++ + Y+D+NG Q + +RP + + +A NYYP+V ++
Sbjct: 60 LNREAVLRTSTNLNSQQVIYSDNNGYQ-----MQRRPYVSY-VNNSIARNYYPMVQSAFM 113
Query: 353 ENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLH--DDAFGVGEALNETVLGQPLV 517
E+ R +L++RA G +S G++++M+HRRL + D G LN+T + P++
Sbjct: 114 EDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVL 170
>BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/117 (29%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 173 VGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEPVAGNYYPVVNEIYI 352
+ ++ VL T++ + Y+D+NG Q + +RP + + +A NYYP+V ++
Sbjct: 711 LNREAVLRTSTNLNSQQVIYSDNNGYQ-----MQRRPYVSY-VNNSIARNYYPMVQSAFM 764
Query: 353 ENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLH--DDAFGVGEALNETVLGQPLV 517
E+ R +L++RA G +S G++++M+HRRL + D G LN+T + P++
Sbjct: 765 EDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVL 821
>AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein
protein.
Length = 1009
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/117 (29%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 173 VGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEPVAGNYYPVVNEIYI 352
+ ++ VL T++ + Y+D+NG Q + +RP + + +A NYYP+V ++
Sbjct: 711 LNREAVLRTSTNLNSQQVIYSDNNGYQ-----MQRRPYVSY-VNNSIARNYYPMVQSAFM 764
Query: 353 ENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLH--DDAFGVGEALNETVLGQPLV 517
E+ R +L++RA G +S G++++M+HRRL + D G LN+T + P++
Sbjct: 765 EDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVL 821
>AB023152-1|BAA76779.2| 952|Homo sapiens KIAA0935 protein protein.
Length = 952
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/117 (29%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 173 VGKDVVLTYKTDILNNGQFYTDSNGRQILKRVLNKRPQWNVTLEEPVAGNYYPVVNEIYI 352
+ ++ VL T++ + Y+D+NG Q + +RP + + +A NYYP+V ++
Sbjct: 709 LNREAVLRTSTNLNSQQVIYSDNNGYQ-----MQRRPYVSY-VNNSIARNYYPMVQSAFM 762
Query: 353 ENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLH--DDAFGVGEALNETVLGQPLV 517
E+ R +L++RA G +S G++++M+HRRL + D G LN+T + P++
Sbjct: 763 EDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVL 819
>D55649-1|BAA09510.1| 1139|Homo sapiens alpha mannosidase II isozyme
protein.
Length = 1139
Score = 52.8 bits (121), Expect = 8e-07
Identities = 22/62 (35%), Positives = 42/62 (67%)
Frame = +2
Query: 308 PVAGNYYPVVNEIYIENDDQRFTVLTDRAAGGASLVEGEIQLMVHRRLLHDDAFGVGEAL 487
P+ N+YP+ YI++ +R T+ T +A G +SL +G++++++ RRL+ DD G+G+ L
Sbjct: 906 PLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGL 965
Query: 488 NE 493
+
Sbjct: 966 KD 967
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,938,932
Number of Sequences: 237096
Number of extensions: 1552224
Number of successful extensions: 2905
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 2788
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2900
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5646880600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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