Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0004_M19
(501 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4; ... 241 8e-63
UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocystei... 198 6e-50
UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-... 198 6e-50
UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA... 187 1e-46
UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine... 180 2e-44
UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome sh... 154 1e-36
UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella ve... 152 5e-36
UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=3... 142 5e-33
UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1; ... 141 7e-33
UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;... 128 9e-29
UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG... 127 2e-28
UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase, putat... 117 2e-25
UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1; Ja... 115 5e-25
UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;... 115 7e-25
UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;... 114 9e-25
UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 113 2e-24
UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2; ... 112 5e-24
UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-23
UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2; ... 108 6e-23
UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1; Pl... 107 1e-22
UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1; ... 107 2e-22
UniRef50_UPI000050FD2A Cluster: COG2040: Homocysteine/selenocyst... 105 4e-22
UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 104 1e-21
UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of s... 98 8e-20
UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4; ... 93 4e-18
UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1; ... 91 1e-17
UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransfera... 91 1e-17
UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase; ... 81 2e-14
UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase, putat... 77 3e-13
UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_Q2TXK9 Cluster: Predicted protein; n=2; Trichocomaceae|... 75 1e-12
UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of str... 72 6e-12
UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2; ... 71 2e-11
UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1; ... 68 1e-10
UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;... 67 2e-10
UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10
UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein NCU007... 64 2e-09
UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Re... 59 6e-08
UniRef50_A5UPF4 Cluster: Methionine synthase; n=4; Chloroflexace... 56 6e-07
UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1; ... 54 1e-06
UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase, putat... 53 4e-06
UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1; ... 52 6e-06
UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=... 52 7e-06
UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine m... 52 1e-05
UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25; Cyanobacteri... 51 1e-05
UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:... 51 2e-05
UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine syntha... 50 4e-05
UniRef50_Q93A68 Cluster: Methylenetetrahydrofolate reductase; n=... 49 5e-05
UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family... 49 5e-05
UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associa... 48 9e-05
UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1; ... 48 1e-04
UniRef50_Q1IQK2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 48 2e-04
UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase, putat... 47 2e-04
UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase, putat... 47 2e-04
UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 47 2e-04
UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to 5-methylte... 46 4e-04
UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium... 46 4e-04
UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1; ... 46 4e-04
UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9... 46 4e-04
UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;... 46 5e-04
UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Re... 46 6e-04
UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2; ... 46 6e-04
UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1; ... 45 8e-04
UniRef50_Q99707 Cluster: Methionine synthase; n=268; cellular or... 45 8e-04
UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine ... 44 0.002
UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=... 44 0.002
UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5; ... 44 0.003
UniRef50_P74718 Cluster: Slr1189 protein; n=1; Synechocystis sp.... 43 0.003
UniRef50_Q2AGF5 Cluster: Dihydropteroate synthase, DHPS:Homocyst... 43 0.003
UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1; ... 43 0.004
UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;... 42 0.006
UniRef50_Q6AL45 Cluster: Related to 5-methyltetrahydrofolate--ho... 42 0.006
UniRef50_Q024B4 Cluster: Homocysteine S-methyltransferase; n=1; ... 42 0.006
UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:... 42 0.006
UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.006
UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family... 42 0.006
UniRef50_A7DNT5 Cluster: Homocysteine S-methyltransferase; n=1; ... 42 0.006
UniRef50_Q55786 Cluster: Methionine synthase; n=5; Cyanobacteria... 42 0.006
UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine... 42 0.010
UniRef50_A7CWS4 Cluster: Homocysteine S-methyltransferase precur... 42 0.010
UniRef50_Q4WFR2 Cluster: Homocysteine S-methyltransferase, putat... 41 0.014
UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransfera... 41 0.018
UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 41 0.018
UniRef50_A0RW49 Cluster: Methionine synthase I (Cobalamin-depend... 40 0.024
UniRef50_Q748M7 Cluster: Methylenetetrahydrofolate reductase; n=... 40 0.031
UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 40 0.031
UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;... 40 0.042
UniRef50_Q9I2Q2 Cluster: Methionine synthase; n=95; Bacteria|Rep... 40 0.042
UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=... 39 0.055
UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1; ... 39 0.055
UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella suc... 39 0.073
UniRef50_Q9WYU7 Cluster: Putative uncharacterized protein; n=2; ... 38 0.096
UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3; ... 38 0.096
UniRef50_A6QBA6 Cluster: 5-methyltetrahydrofolate--homocysteine ... 38 0.096
UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep... 38 0.096
UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family... 38 0.13
UniRef50_Q8DCJ7 Cluster: Methionine synthase; n=51; Bacteria|Rep... 38 0.13
UniRef50_Q9WYA5 Cluster: 5-methyltetrahydrofolate S-homocysteine... 37 0.22
UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2; ... 37 0.29
UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=... 37 0.29
UniRef50_Q1NSQ8 Cluster: Methylenetetrahydrofolate reductase; n=... 36 0.51
UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 36 0.51
UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine ... 36 0.68
UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4; ... 35 0.90
UniRef50_Q49775 Cluster: Methionine synthase; n=19; Bacteria|Rep... 35 0.90
UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=... 35 1.2
UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep... 35 1.2
UniRef50_A3J3G3 Cluster: Lycopene cyclase; n=2; Flavobacteriales... 35 1.2
UniRef50_Q4AEC2 Cluster: Chalcone synthase; n=48; Spermatophyta|... 34 2.1
UniRef50_Q8R927 Cluster: Methionine synthase I, cobalamin-bindin... 33 2.7
UniRef50_Q1GGL5 Cluster: Homocysteine S-methyltransferase; n=30;... 33 2.7
UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4; ... 33 2.7
UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransfera... 33 2.7
UniRef50_Q1WUH1 Cluster: TRNA delta(2)-isopentenylpyrophosphate ... 33 3.6
UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2; ... 33 3.6
UniRef50_Q6MCZ9 Cluster: Putative uncharacterized protein; n=1; ... 33 4.8
UniRef50_Q67LG1 Cluster: 5-methyltetrahydrofolate S-homocysteine... 33 4.8
UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine... 33 4.8
UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2; ... 33 4.8
UniRef50_A3GFY2 Cluster: Saccharolysin; n=7; Saccharomycetales|R... 33 4.8
UniRef50_Q1ET86 Cluster: Hydrolase, predicted metal dependent ph... 32 6.3
UniRef50_A4Z1H6 Cluster: Putative uncharacterized protein; n=1; ... 32 6.3
UniRef50_Q4YA86 Cluster: Putative uncharacterized protein; n=1; ... 32 6.3
UniRef50_Q22HI1 Cluster: Homocysteine S-methyltransferase family... 32 8.3
>UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4;
Endopterygota|Rep: Homocysteine S-methyltransferase -
Bombyx mori (Silk moth)
Length = 325
Score = 241 bits (589), Expect = 8e-63
Identities = 112/166 (67%), Positives = 134/166 (80%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
T VLDGGFSTQL+CH G DGDPL SARFL THP +V+NTHLDFL AG+D+I TNTYQ
Sbjct: 10 TVFVLDGGFSTQLTCHAGHTADGDPLGSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQ 69
Query: 183 ASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGA 362
ASV+G ++HL LT +ESYELI AVE A+ AR LYL+E Q+ + R PL+ GSVGPYGA
Sbjct: 70 ASVDGLVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGA 129
Query: 363 HLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
+LHD SEY G+YAD T+ +T+++WHR RIQALVEAGVD+LA ETIP
Sbjct: 130 YLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIP 175
>UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocysteine
S-methyltransferase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to homocysteine S-methyltransferase -
Nasonia vitripennis
Length = 341
Score = 198 bits (483), Expect = 6e-50
Identities = 90/165 (54%), Positives = 127/165 (76%), Gaps = 1/165 (0%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+++DGGFSTQL HVG+VIDGDPLW++RFL+++PD V THLD+L AG+ +I T TYQAS
Sbjct: 24 IIIDGGFSTQLVTHVGEVIDGDPLWTSRFLYSNPDAVFQTHLDYLRAGSHVIETATYQAS 83
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
+ G++++L T +E+ +LI AVELAK+A +Y EE + ++ P+V GS+GPY A+L
Sbjct: 84 IPGYVKYLDRTEEEALQLIKTAVELAKKAVRVYKEEIKGKDVSNPEPMVAGSIGPYAAYL 143
Query: 369 HDGSEY-DGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
HD SEY GSYA+ S+ ++ +WHRPR +AL+ GVD+LA+ETIP
Sbjct: 144 HDCSEYTGGSYANIESMDSIVEWHRPRFEALINGGVDLLAIETIP 188
>UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-PA
- Drosophila melanogaster (Fruit fly)
Length = 331
Score = 198 bits (483), Expect = 6e-50
Identities = 89/160 (55%), Positives = 125/160 (78%)
Frame = +3
Query: 21 GGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGF 200
GGFS+QL+ +V + +DGDPLW +RF T+P+ V+ THLDFL GAD+I+TNTYQ+SVEGF
Sbjct: 19 GGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGF 78
Query: 201 IEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGS 380
+++LG+TR+ ELI ++V+LAK+A+ YL E ++ +PL++GS+GPYGA+LHDGS
Sbjct: 79 VKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAES-ALPLIMGSIGPYGAYLHDGS 137
Query: 381 EYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
EY G+YAD S + +R WH+ RI+ + AGVD LALET+P
Sbjct: 138 EYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLP 177
>UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to
CG10621-PA - Apis mellifera
Length = 320
Score = 187 bits (456), Expect = 1e-46
Identities = 87/165 (52%), Positives = 122/165 (73%), Gaps = 2/165 (1%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDGGF QLS HV + +DGDPLW+++FL T+P+ V THLDFL AGAD+I TNTYQAS+
Sbjct: 5 ILDGGFGAQLSTHVNEKVDGDPLWTSKFLVTNPNAVYATHLDFLKAGADIIETNTYQASI 64
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEY--QDYVQNDRVPLVVGSVGPYGAH 365
++HL ++++ES +L+ +AV LAK A + Y +E + V+N + P++V S GPYGA
Sbjct: 65 PSLMKHLSISKEESIKLLHKAVHLAKTAVNDYTKEVINNNDVEN-KNPMIVASCGPYGAS 123
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
LHDGSEY+G+Y T + + WH+ RI A++ AG+D+LALETIP
Sbjct: 124 LHDGSEYNGAYGKITPRENIIQWHKSRIDAIINAGIDLLALETIP 168
>UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine
S-methyltransferase domain; n=7; Euteleostomi|Rep: Novel
protein containing a homocysteine S-methyltransferase
domain - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 318
Score = 180 bits (437), Expect = 2e-44
Identities = 82/163 (50%), Positives = 118/163 (72%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDGG +T+L G + GDPLWSAR LHT P + + H +L +G+D+I T TYQAS+
Sbjct: 14 ILDGGLATELEAS-GFQLQGDPLWSARVLHTDPQAIKDVHYRYLQSGSDVITTATYQASI 72
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLH 371
EGF+++LG+ +E+ +++ AV+LAK S ++ Q + + R PLV GSVGPYG+ LH
Sbjct: 73 EGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFIS--QSPMSDRREPLVAGSVGPYGSFLH 130
Query: 372 DGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G+Y D +V+ ++DWHRP+IQ LV+AG D++A+ETIP
Sbjct: 131 DGSEYTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIP 173
>UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 1
SCAF14770, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 372
Score = 154 bits (373), Expect = 1e-36
Identities = 82/185 (44%), Positives = 115/185 (62%), Gaps = 22/185 (11%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDGG +T L G + GDPLWSAR L+T+P + + H FL++GAD+I T TYQASV
Sbjct: 18 ILDGGLATDLEAQ-GVHLQGDPLWSARLLYTNPQAIRDAHCRFLLSGADVISTATYQASV 76
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRARSLY---------LEEYQDYVQND-------- 320
EGF++HL ++ + + ELI+ V+LAK A + ++ + V ++
Sbjct: 77 EGFMDHLNVSSEGAKELIMSGVQLAKEAVESFVPGTNPNTTVQSGEGKVNSEGSEGLAGQ 136
Query: 321 -----RVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLA 485
R PLV GS+GPYGA LH+GSEY G YA+ SVQ ++ WHRP+++ L A D+LA
Sbjct: 137 CSSGRRCPLVAGSLGPYGAFLHNGSEYTGDYAEKMSVQELKAWHRPQVECLAAAEADVLA 196
Query: 486 LETIP 500
ETIP
Sbjct: 197 FETIP 201
>UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 265
Score = 152 bits (368), Expect = 5e-36
Identities = 74/146 (50%), Positives = 98/146 (67%)
Frame = +3
Query: 63 IDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYEL 242
+ GDPLWSAR L +P+ V H FL G+D+I T TYQAS+ GF +HLG+T E+ +L
Sbjct: 3 MQGDPLWSARVLVENPEAVKQVHKSFLTHGSDIITTATYQASISGFCKHLGVTADEARKL 62
Query: 243 IVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQT 422
I R V +A+ + ++E+ D N P V GSV PYG DGSEY G+Y DT +++
Sbjct: 63 IQRGVHIARES----VDEFWDKHSNS--PQVAGSVCPYGTCQSDGSEYHGNYVDTMTIKN 116
Query: 423 MRDWHRPRIQALVEAGVDMLALETIP 500
+ DWHRP+IQALVE G+D+LA ETIP
Sbjct: 117 LMDWHRPQIQALVETGLDLLAFETIP 142
>UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=30;
Magnoliophyta|Rep: Homocysteine S-methyltransferase 3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 347
Score = 142 bits (343), Expect = 5e-33
Identities = 76/171 (44%), Positives = 110/171 (64%), Gaps = 8/171 (4%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
V+DGGF+T+L H + DPLWSA+ L T P V HLD+L +GA++IIT +YQA++
Sbjct: 25 VVDGGFATELQRHGADI--NDPLWSAKCLITSPHLVTKVHLDYLESGANIIITASYQATI 82
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQ----DYV---QNDRVP-LVVGSV 347
+GF+ GL+ E+ L+ R+VE+ AR ++ D+ + R P LV SV
Sbjct: 83 QGFVAK-GLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWDFAYAGKASRRPILVAASV 141
Query: 348 GPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
G YGA+L DGSEY G Y D+ S +T++D+HR R+Q L ++G D++A ETIP
Sbjct: 142 GSYGAYLADGSEYSGIYGDSVSKETLKDFHRRRVQILAKSGADLIAFETIP 192
>UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 319
Score = 141 bits (342), Expect = 7e-33
Identities = 78/172 (45%), Positives = 113/172 (65%), Gaps = 8/172 (4%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+++DG +T L H+G I G LWSA L + PD + THLD+ AGA++ IT +YQAS
Sbjct: 18 LLIDGALATYLE-HLGADISGS-LWSASILLSRPDLIKKTHLDYYRAGANIAITASYQAS 75
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLE-EYQDYVQN--DRVPL-----VVGS 344
+ G ++HLGL E+ +++ ++V+LA AR Y++ + ++ + D L V GS
Sbjct: 76 IPGLVKHLGLGENEAKDVVKKSVQLAIEARDEYVQSKLEESCERSVDAASLREDLFVAGS 135
Query: 345 VGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
VGPYGA+L DGSEY G Y + + M+D+HR R+QALV+AGVD+LA ETIP
Sbjct: 136 VGPYGAYLSDGSEYRGDY--DVAHEAMKDFHRGRVQALVDAGVDVLACETIP 185
>UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;
Bacteria|Rep: Homocysteine S-methyltransferase -
Escherichia coli (strain K12)
Length = 310
Score = 128 bits (308), Expect = 9e-29
Identities = 73/164 (44%), Positives = 100/164 (60%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LDG +T+L + D LWSA+ L +P+ + HLD+ AGA IT +YQA+
Sbjct: 17 LLLDGAMATELEARGCNLADS--LWSAKVLVENPELIREVHLDYYRAGAQCAITASYQAT 74
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
GF GL +S LI ++VELA++AR YL E LV GSVGPYGA+L
Sbjct: 75 PAGFAAR-GLDEAQSKALIGKSVELARKAREAYLAEN----PQAGTLLVAGSVGPYGAYL 129
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G Y SV+ + +HRPR++AL++AG D+LA ET+P
Sbjct: 130 ADGSEYRGDY--HCSVEAFQAFHRPRVEALLDAGADLLACETLP 171
>UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG
protein - Bacillus subtilis
Length = 315
Score = 127 bits (306), Expect = 2e-28
Identities = 69/164 (42%), Positives = 102/164 (62%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+VLDG +T+L G ++ D LWSA+ L P+ + H D+ AGAD IT +YQ++
Sbjct: 14 IVLDGAMATELE-RKGCNLN-DSLWSAKILMEEPELIKQVHTDYFAAGADCAITASYQST 71
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
EGF GL+ E+ LI +V +A AR + ++ + + P++ S+GPYGA+L
Sbjct: 72 FEGFAAR-GLSEAEARRLIELSVSIAAEARDEFWSLEENRLNRPK-PIIAASIGPYGAYL 129
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G+YA S + ++HRPR++AL+EAG D+LA ETIP
Sbjct: 130 ADGSEYRGNYA--ISEDELIEFHRPRMKALIEAGADVLACETIP 171
>UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Leishmania|Rep: Homocysteine
S-methyltransferase, putative - Leishmania major
Length = 339
Score = 117 bits (281), Expect = 2e-25
Identities = 69/165 (41%), Positives = 96/165 (58%), Gaps = 1/165 (0%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+LDGG +T+L + DPLWS + L P ++ N L +L AGA IIT +YQ +
Sbjct: 31 VMLDGGLATELETRGCDL--RDPLWSGKVLLESPQQLQNVALAYLRAGARCIITASYQIT 88
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPL-VVGSVGPYGAH 365
+ +EH LT + I +V +A+ AR +L E + P+ V GSVGPYGA+
Sbjct: 89 PQSLMEHRRLTEDAAVAAIEESVRIAQSARERHLRE-----KPQAAPIFVAGSVGPYGAY 143
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
L DGSEY G Y S + +++HR RI AL+ AG D+LA+ET P
Sbjct: 144 LADGSEYRGDY--VRSAEEFKEFHRLRIAALLRAGADVLAIETQP 186
>UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1;
Janibacter sp. HTCC2649|Rep: Homocysteine
methyltransferase - Janibacter sp. HTCC2649
Length = 305
Score = 115 bits (277), Expect = 5e-25
Identities = 73/164 (44%), Positives = 97/164 (59%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
VVLDGGFST L G + G LWSAR L P EVV H F+ AGA+++I+ +YQAS
Sbjct: 23 VVLDGGFSTALEAR-GHDLSGR-LWSARLLRQAPSEVVAAHRTFVDAGAEIVISASYQAS 80
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
G++ GLT +E + ++ELA++ D LV SVGPYGAHL
Sbjct: 81 HAGYVA-AGLTEEECDADLDASIELARQGA-------------DGRALVAASVGPYGAHL 126
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G A S T+R++H R++ L+ AG D++A+ETIP
Sbjct: 127 ADGSEYTGYPA--VSRATLREFHSRRLERLIAAGPDLVAVETIP 168
>UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;
Streptococcus|Rep: Homocysteine S-methyltransferase -
Streptococcus agalactiae H36B
Length = 351
Score = 115 bits (276), Expect = 7e-25
Identities = 63/165 (38%), Positives = 101/165 (61%), Gaps = 1/165 (0%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++L G T+L G + G LWS ++L P + H D++ AGAD++ T+TYQA+
Sbjct: 51 LILHGALGTELESR-GCDVSGK-LWSDKYLIEDPAAIQTIHEDYIRAGADIVTTSTYQAT 108
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRV-PLVVGSVGPYGAH 365
++G + +G++ ++ +LI V+LAK R + +++R+ PL+ G VGPY A
Sbjct: 109 LQG-LAQVGVSESQAEDLIRLTVQLAKAVREQVWKSLTKEEKSERIYPLISGDVGPYAAF 167
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
L DGSEY G Y + ++++HR RI+ L++ GVD+LALETIP
Sbjct: 168 LADGSEYTGLY--DIYKEGLKNFHRHRIELLLDEGVDLLALETIP 210
>UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;
Actinomycetales|Rep: Homocysteine S-methyltransferase -
Mycobacterium tuberculosis
Length = 302
Score = 114 bits (275), Expect = 9e-25
Identities = 71/164 (43%), Positives = 92/164 (56%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++ DGG +T+L + DPLWSAR L P + H + AGA + T +YQAS
Sbjct: 9 LISDGGLATELEARGHDL--SDPLWSARLLVDAPHAITAVHTAYFRAGAQIATTASYQAS 66
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
EGF G+ ++ L+ R+VELA+ AR D V + V SVGPYGA L
Sbjct: 67 FEGFAAR-GIGHDDATVLLRRSVELAQAAR--------DEVGVGGLS-VAASVGPYGAAL 116
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G Y SV + WH PR++ LV+AG DMLAL+TIP
Sbjct: 117 ADGSEYRGCYG--LSVAALMKWHLPRLEVLVDAGADMLALKTIP 158
>UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2;
Bacteria|Rep: Homocysteine S-methyltransferase -
Lactobacillus plantarum
Length = 309
Score = 113 bits (272), Expect = 2e-24
Identities = 68/164 (41%), Positives = 96/164 (58%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
VV DG +T+L V LWSA + HPD + H +L AGA ++ TNTYQA+
Sbjct: 13 VVSDGAMATELEKR--GVATNSALWSATAMLDHPDAIQAVHQSYLDAGAKIMTTNTYQAN 70
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
V F E G+ ++ +LI +AV +A AR +V + ++ GS+GPYGA+L
Sbjct: 71 VPAF-EQAGIAAVQARQLIQQAVTIAHTARD------ASHVTD---AVIAGSIGPYGAYL 120
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G+Y T S +D+HR R+ ++ AGVD+LALET+P
Sbjct: 121 ADGSEYTGAYQLTPS--AYQDFHRERLALIMAAGVDVLALETMP 162
>UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep:
Homocysteine S-methyltransferase - Lactobacillus
delbrueckii subsp. bulgaricus (strain ATCC 11842 /
DSM20081)
Length = 310
Score = 112 bits (269), Expect = 5e-24
Identities = 71/164 (43%), Positives = 97/164 (59%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V LDG ST L G+ + D LW+A+ L +PD V H ++ AGA + IT++YQAS
Sbjct: 13 VTLDGSMSTPLEAW-GEDTNSD-LWTAKALADNPDLVYRVHQEYFKAGARVTITDSYQAS 70
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
+ F++H GL+ + LI + +A +AR + E + + N V GSVGPYGA+L
Sbjct: 71 LPAFMKH-GLSEDAARALIRESAAVAIKARDDF--EKETGIHN----FVAGSVGPYGAYL 123
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G YA S + D+H PRI+ LV GVD LA+ET P
Sbjct: 124 ADGSEYRGDYA--LSHEEYVDFHAPRIEELVAGGVDCLAVETQP 165
>UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 347
Score = 99.1 bits (236), Expect(2) = 1e-23
Identities = 60/142 (42%), Positives = 85/142 (59%), Gaps = 18/142 (12%)
Frame = +3
Query: 129 HLDFLIAGADLIITNTYQA-SVEGFIEHL---GLTRKESYELIVR-----AVELAKRARS 281
HLD+L AGAD+IIT +YQ S ++ L GL + S E V+ +VE+A AR
Sbjct: 90 HLDYLEAGADIIITASYQVNSAYIYVNRLLFRGLKLEASLEEKVKPCLGKSVEIACEARK 149
Query: 282 LYLEEYQDYVQND---------RVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDW 434
+Y + ++ +D R LV SVG YGA+L DGSEY G Y D +V+T++D+
Sbjct: 150 MYYDRCIEFACDDXEDGRILKHRPILVAASVGSYGAYLADGSEYSGIYGDEITVETLKDF 209
Query: 435 HRPRIQALVEAGVDMLALETIP 500
HR R+Q L +AG D++A ET+P
Sbjct: 210 HRRRVQILADAGADLIAFETVP 231
Score = 32.7 bits (71), Expect(2) = 1e-23
Identities = 18/47 (38%), Positives = 27/47 (57%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAG 152
V+DGG +T+L H + DPLWSA+ L + P ++ T F+ G
Sbjct: 24 VIDGGLATELERHGADL--NDPLWSAKCLLSSP-HLIRTGSRFVNLG 67
>UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus reuteri|Rep: Homocysteine
S-methyltransferase - Lactobacillus reuteri F275
Length = 310
Score = 108 bits (260), Expect = 6e-23
Identities = 66/164 (40%), Positives = 97/164 (59%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+++DG ST L +G + LW+A L P V H ++ AG L IT+TYQA+
Sbjct: 12 LLIDGAMSTALE-QLGADTNNS-LWTASVLANQPALVKKVHQEYFKAGDRLAITDTYQAN 69
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
V FI++ G +++E++ LI RAV LAK AR Y +E Y V G++GPYGA+L
Sbjct: 70 VPAFIKN-GYSKQEAHSLIQRAVVLAKEARDEYQQETGIY------NYVAGALGPYGAYL 122
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
+GSEY G+Y S + +HRPR+ ++ GVD++A+ET P
Sbjct: 123 ANGSEYSGAY--HLSTIEYQQFHRPRLTDILTVGVDVIAIETQP 164
>UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Homocysteine
methyltransferase - Plesiocystis pacifica SIR-1
Length = 325
Score = 107 bits (257), Expect = 1e-22
Identities = 68/163 (41%), Positives = 91/163 (55%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
VLDGG +T L G +D DPLWSAR L P+ + H + AGAD++ T +YQAS+
Sbjct: 22 VLDGGLATSLEA-CGCDLD-DPLWSARLLLDDPEALRTVHRRWRDAGADILATASYQASL 79
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLH 371
G + GL+ + L+ +V L + A D R PL+ SVG YGA+L
Sbjct: 80 PG-LRAKGLSEARAKALLRESVTLTRAA--------ADEANAPR-PLIAASVGSYGAYLA 129
Query: 372 DGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G Y SV+ + D+HRPR+ L AG D++A ET P
Sbjct: 130 DGSEYRGGYG--LSVEALADFHRPRLLELAAAGPDLIAFETFP 170
>UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep: Homocysteine
S-methyltransferase - Granulobacter bethesdensis (strain
ATCC BAA-1260 / CGDNIH1)
Length = 313
Score = 107 bits (256), Expect = 2e-22
Identities = 65/165 (39%), Positives = 92/165 (55%), Gaps = 1/165 (0%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LDG +T+L G +D DPLWS R L +P + H +L AGAD I T +YQ S
Sbjct: 15 LLLDGALATELE-RAGYHLD-DPLWSGRLLLDNPAAIAAVHRAYLEAGADCIETASYQLS 72
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRV-PLVVGSVGPYGAH 365
+ G ++ GL+R + ++ A LA R + +R+ PLV GS+GPYGA
Sbjct: 73 LPG-LQRRGLSRGRAMSVLADAARLACSVRDDVWAGLPAAQRRNRIRPLVAGSLGPYGAC 131
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G YA + S +H PR++AL G D++A ET+P
Sbjct: 132 QADGSEYTGRYALSRSQYLA--FHAPRMRALAAGGADLIACETVP 174
>UniRef50_UPI000050FD2A Cluster: COG2040:
Homocysteine/selenocysteine methylase
(S-methylmethionine-dependent); n=1; Brevibacterium
linens BL2|Rep: COG2040: Homocysteine/selenocysteine
methylase (S-methylmethionine-dependent) -
Brevibacterium linens BL2
Length = 308
Score = 105 bits (253), Expect = 4e-22
Identities = 69/165 (41%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVID-GDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQA 185
+V+DGG T L + ID LWSA L PD + H DF+ AGA ++ T +YQA
Sbjct: 19 LVIDGGLGTALE---SRGIDLSHELWSAALLRDSPDTLAEVHADFIRAGAQIVTTASYQA 75
Query: 186 SVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAH 365
+ GF E + +E LI R+VE+A A LV GSVGPYGA
Sbjct: 76 TPLGF-ERASIPAEEGLRLIARSVEIAAGAGDA---------------LVAGSVGPYGAA 119
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
L +G+EY G Y S + +HRPRI+ALV AG D+LA+ET P
Sbjct: 120 LGNGAEYTGDYH--LSDEEFAAFHRPRIEALVNAGADLLAIETQP 162
>UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus|Rep: Homocysteine S-methyltransferase -
Lactobacillus acidophilus
Length = 310
Score = 104 bits (249), Expect = 1e-21
Identities = 64/164 (39%), Positives = 96/164 (58%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LDG ST L V + LW+A L D+V H+++ +GA + ITNTYQA+
Sbjct: 12 LILDGAMSTALEKQ--GVNTNNDLWTAVALENDLDKVYKVHMNYFKSGAQMTITNTYQAN 69
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
V+ F +H G + + + +LI AV++AK+AR ++YQ Q + V SVGPYGA+L
Sbjct: 70 VQAFKKH-GYSDEHTKKLITDAVQIAKKAR----DDYQ--TQTGKHNWVAASVGPYGAYL 122
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DG E+ G Y+ T + +H PR++ L+E D LA+ET P
Sbjct: 123 SDGDEFRGDYSLTP--KEYLAFHLPRLKILLENKPDCLAIETQP 164
>UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome A of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 351
Score = 98.3 bits (234), Expect = 8e-20
Identities = 60/178 (33%), Positives = 97/178 (54%), Gaps = 14/178 (7%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGD-------PLWSARFLHTHPDEVVNTHLDFLIAGADLII 167
+V+DG TQL +++ D PLWSA L +P+ + H D++ +GA++I
Sbjct: 14 LVIDGALGTQLETKFSKLLQQDNINIQTHPLWSALVLLKNPELIQEVHYDYMCSGANIIT 73
Query: 168 TNTYQASVEGFIEHL-GLTRKESYELIV-RAVELAKRARSLYLEEY---QDYVQNDRVPL 332
T+TYQAS G +E+ G+ + + +A+ELA ARS YLE + + N +
Sbjct: 74 TSTYQASKRGLLEYAPGIENDDEVNAVYDKAIELAVDARSQYLENMGKGMNTLTNKEI-F 132
Query: 333 VVGSVGPYGAHLHDGSEYDGSY-ADTTSVQTMRDWHRP-RIQALVEAGVDMLALETIP 500
+ GS+GP+GA+L +G+EY G Y + T Q ++ +H Q + D++ ETIP
Sbjct: 133 ICGSIGPFGAYLANGAEYTGKYGSHITEPQELKKFHYDITSQFISNPKCDIIGFETIP 190
>UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4;
n=1; Candida albicans|Rep: Putative uncharacterized
protein SAM4 - Candida albicans (Yeast)
Length = 311
Score = 92.7 bits (220), Expect = 4e-18
Identities = 55/169 (32%), Positives = 90/169 (53%), Gaps = 4/169 (2%)
Frame = +3
Query: 6 RVVLDGGFSTQLSCHVGQVI----DGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITN 173
++V+DG T+L + G PLWS + L +P+ V HLD++ GAD+IIT+
Sbjct: 12 KLVIDGALGTELERLLPTTSTYLPSGSPLWSGQVLIKNPELVEQVHLDYINVGADMIITS 71
Query: 174 TYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGP 353
TYQ S +++G ++ L A+ +AK A + +D V ++ GS+GP
Sbjct: 72 TYQTSYASLHKYIGYDMDQAIALWNSALNVAKNA---VKKSGRDDV------IIAGSIGP 122
Query: 354 YGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
Y L +GSEY+G Y T + + ++H P + + VD++ +ETIP
Sbjct: 123 YATLLANGSEYNGDYQGVTD-EELIEYHTPLFEFYENSDVDIICIETIP 170
>UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 326
Score = 91.5 bits (217), Expect = 1e-17
Identities = 57/176 (32%), Positives = 93/176 (52%), Gaps = 11/176 (6%)
Frame = +3
Query: 6 RVVLDGGFSTQLSCHVGQ----VIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITN 173
+VVLDG T L + + PLWS + L P+ + H ++ AG+++I T+
Sbjct: 9 KVVLDGALGTALEDLIDPSAPYLPSKSPLWSGQVLLDAPELIQKVHEMYIGAGSEVIFTS 68
Query: 174 TYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDR------VPLV 335
TYQ S + +H L+ ++ E+ R+++L RA +L ++E Y + +
Sbjct: 69 TYQLSYDSLRKHTTLSDEQILEVWQRSIDLV-RAAALSIDETARYTKEKESRGEPGKVHI 127
Query: 336 VGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVE-AGVDMLALETIP 500
GS+GPY A+L +GSEY G Y + T Q + +H P ++ E VD++A ETIP
Sbjct: 128 AGSIGPYAAYLANGSEYTGDYGNVTDEQ-LEAFHTPMLEFFTENEAVDLIAFETIP 182
>UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransferase;
n=1; Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305|Rep: Putative homocysteine
S-methyltransferase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 301
Score = 91.1 bits (216), Expect = 1e-17
Identities = 58/164 (35%), Positives = 88/164 (53%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+VLDGG +T L G + LWS+ L +P ++ H F GAD+++T+TYQAS
Sbjct: 13 LVLDGGLATTLE-QAGCSLKTS-LWSSEVLKNNPTQIKQAHQAFTDVGADILLTSTYQAS 70
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
+ F + +G+ E +L AV A + ++VGS+GPYGA+L
Sbjct: 71 YQTFSD-IGMKATEIDQLYNTAVNQIMEATT-------------DTQVIVGSLGPYGAYL 116
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
DGSEY G+Y S + +H+ RI+ALV+ G++ ET+P
Sbjct: 117 SDGSEYTGAY--DLSKEDYFQFHKTRIEALVKRGINDFVFETVP 158
>UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 313
Score = 80.6 bits (190), Expect = 2e-14
Identities = 55/168 (32%), Positives = 82/168 (48%), Gaps = 4/168 (2%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQ---VIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTY 179
+VLDGG QL + + DPLWS R L PD + + H FL AG D++ T+TY
Sbjct: 7 LVLDGGLGIQLETLAEKRNFAVKNDPLWSGRALIEAPDLIEDVHKSFLEAGCDIVTTSTY 66
Query: 180 QASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYG 359
Q S ++ T + EL ++V++ +A + + + V G++GPYG
Sbjct: 67 QISRASLKKYTDFTDAQIEELWAKSVDVCWQACKFHESKAR----------VCGAIGPYG 116
Query: 360 AHLHDGSEYDGSYADTTSVQTMRDWHRPRIQAL-VEAGVDMLALETIP 500
L + +EY G Y T+ + +H P L VD+LA ETIP
Sbjct: 117 GFLANYAEYTGEYGLITN-HKLEQYHLPLATFLNNNPKVDILAFETIP 163
>UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase;
n=1; Pichia stipitis|Rep: AdoMet-homocysteine
methyltransferase - Pichia stipitis (Yeast)
Length = 337
Score = 80.6 bits (190), Expect = 2e-14
Identities = 52/172 (30%), Positives = 89/172 (51%), Gaps = 7/172 (4%)
Frame = +3
Query: 6 RVVLDGGFSTQLSCHVGQVID----GDPLWSARFLHTHPDEVVNTHLDFLI-AGADLIIT 170
R+VLDG T+L + + PLWS L P+ + N H ++L A D +I+
Sbjct: 12 RLVLDGAMGTELEACIPKDSKIQPRKHPLWSGLVLLNEPNLIKNVHYNYLEQADVDALIS 71
Query: 171 NTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPL-VVGSV 347
+TYQ S EH L ++ + +++++ + A + +Y+ N + + ++GS+
Sbjct: 72 STYQISYPSLKEHTDLDDEQIRGIWKKSIDVVEDA----ILQYRSKNSNSKKKIYIIGSI 127
Query: 348 GPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQ-ALVEAGVDMLALETIP 500
GPY +L DGSEY G Y + S + +H+P ++ L + VD + ETIP
Sbjct: 128 GPYATYLADGSEYTGDYKN-ASDSDIESYHQPLLEYFLGDDRVDTIGFETIP 178
>UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Filobasidiella neoformans|Rep:
Homocysteine S-methyltransferase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 381
Score = 76.6 bits (180), Expect = 3e-13
Identities = 53/162 (32%), Positives = 75/162 (46%), Gaps = 3/162 (1%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+VLDGG T L +G I PLW + L T+PD + H ++ GADL+ T TYQ +
Sbjct: 6 LVLDGGMGTTLES-LGVDISS-PLWGSEALRTNPDVIRKVHEGYVQGGADLVETATYQLT 63
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAK---RARSLYLEEYQDYVQNDRVPLVVGSVGPYG 359
+ +HL R+E+ ++ V+L + S EE+ + VV S GPYG
Sbjct: 64 PQNLCDHLHCPREEAECILCSGVKLVASCIASCSSRNEEHNTKSKGGNKSKVVLSFGPYG 123
Query: 360 AHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLA 485
+ L G EY G Y T + P EA + LA
Sbjct: 124 STLQPGQEYGGIYPPPFGPSTSTNAFPPDSNDEEEAAIQALA 165
>UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 448
Score = 74.5 bits (175), Expect = 1e-12
Identities = 63/191 (32%), Positives = 93/191 (48%), Gaps = 28/191 (14%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEV---------VNTHLDFLIAGADLI 164
+LDGG +T L + + PLWSAR L D+V + HL +L AGA +I
Sbjct: 21 ILDGGLATYLEDGLDFDLSKGPLWSARLLDEKEDDVSDGKGQKGIFDAHLHYLQAGAGII 80
Query: 165 ITNTYQASVEGFIEHLGLTRKESYELIVRAVELA---KRARSLYLEEYQDYVQNDRVPLV 335
T TYQAS+E F + + L+ +AV+LA A ++ + PL+
Sbjct: 81 GTATYQASLESFAR-ANYDQVSASHLMSKAVDLACDALHAHNISNNKVGVASAASARPLL 139
Query: 336 VGSVGPYGAHLHDGSEYDGSYADT------------TSVQTMRDWHRPRIQALVE----A 467
S+GPYGA L +G+EY G Y T S++ M +H+ RI+A +
Sbjct: 140 SLSLGPYGAMLSNGAEYTGDYRRTFLAESDPLREQQPSLEEMMAFHQRRIEAFIAQPSWE 199
Query: 468 GVDMLALETIP 500
V +LA+ET+P
Sbjct: 200 HVGVLAVETVP 210
>UniRef50_Q2TXK9 Cluster: Predicted protein; n=2;
Trichocomaceae|Rep: Predicted protein - Aspergillus
oryzae
Length = 376
Score = 74.5 bits (175), Expect = 1e-12
Identities = 54/157 (34%), Positives = 75/157 (47%), Gaps = 5/157 (3%)
Frame = +3
Query: 9 VVLDGGFSTQLSC--HVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
++LDGG T L H PLWSA L + P + H F GAD+I+T TYQ
Sbjct: 9 LLLDGGLGTTLGDPPHNITFTAETPLWSAHLLISSPSTLEEVHKAFATVGADIILTATYQ 68
Query: 183 ASVEGF-IEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYG 359
S EGF + T ++ + A+ LA+RA S + R V S+GPYG
Sbjct: 69 TSFEGFTLTDPRYTADDAAHFMRSAIPLARRAGS----------SSGRTVKVALSLGPYG 118
Query: 360 AHLHD-GSEYDGSY-ADTTSVQTMRDWHRPRIQALVE 464
A + G+EY G Y + S +R+WH R+ V+
Sbjct: 119 ATMSPVGAEYTGLYPEEMNSEAKLREWHARRLCVFVD 155
>UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 348
Score = 72.1 bits (169), Expect = 6e-12
Identities = 47/151 (31%), Positives = 81/151 (53%), Gaps = 1/151 (0%)
Frame = +3
Query: 51 VGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTR-K 227
V + +D P W + + + H D+++AGAD++ + +YQAS+EG I+ + R
Sbjct: 58 VNRALDEHPEW-LESSQDNSNLLYRIHKDYVVAGADIVTSASYQASLEGTIKAGAVQRWP 116
Query: 228 ESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADT 407
E+ ++ ++ +L ++A + + R L+ SVGP+GA L G EY+G Y
Sbjct: 117 EALWMLRKSEQLVRKAVT--------EAKVKRKVLLAASVGPFGAWLGGGQEYNGDYTGY 168
Query: 408 TSVQTMRDWHRPRIQALVEAGVDMLALETIP 500
T +R H +I+A++ DML +ETIP
Sbjct: 169 TK-DDIRRHHEFKIRAVLGGSPDMLLIETIP 198
>UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 369
Score = 70.5 bits (165), Expect = 2e-11
Identities = 65/188 (34%), Positives = 87/188 (46%), Gaps = 25/188 (13%)
Frame = +3
Query: 12 VLDGGFSTQLS-CHVGQVIDGDPLWSARFL---HTH-PDEVVNTHLDFLIAGADLIITNT 176
+LDGG T L H Q + +PLWS++ L H H P ++ T F+ AGAD+++T T
Sbjct: 9 LLDGGLGTTLGDSHQVQFTEKEPLWSSQLLIPTHPHGPKTLLATQKSFVDAGADILLTAT 68
Query: 177 YQASVEGF-------IEHLGLTR------KESYELIVR-AVELAKRARSLYLEEYQDYVQ 314
YQ S EGF H KE I+R AV++A A S +
Sbjct: 69 YQTSYEGFGGSGYAVHSHSSSNSGKADGDKEEVNGIMRSAVDIASDAFSTKKD------S 122
Query: 315 NDRVPLVVGSVGPYGAHLHDGSEYDGSYADT-TSVQTMRDWHRPRIQALVE-----AGVD 476
N ++ L S+G YGA + G EY G Y D S + + WH RI VD
Sbjct: 123 NGKIAL---SLGAYGAIMTPGQEYTGKYDDDHKSSEQLSSWHHERISVFSRDPKCWERVD 179
Query: 477 MLALETIP 500
+A ETIP
Sbjct: 180 YVAFETIP 187
>UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1785
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 11/141 (7%)
Frame = +3
Query: 75 PLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIE------HLGLTRKESY 236
PLWS+ L +HP + H ++ AGAD+++T TYQAS EGF ++ K+
Sbjct: 33 PLWSSHLLLSHPTTLSEIHRSYVDAGADIVLTATYQASFEGFARTAIVPANVPADHKQDE 92
Query: 237 ---ELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHD-GSEYDGSYAD 404
R ++ + RS Y + + + P V S+GPYGA + +EY G Y +
Sbjct: 93 RDGHATYRPMDATRYMRSAIPLAYSSFNFSSKPPRVALSLGPYGATMCPVSAEYTGIYPE 152
Query: 405 TTS-VQTMRDWHRPRIQALVE 464
S + WH R++ +E
Sbjct: 153 EMSNTAALEAWHANRLKVYME 173
>UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;
Pezizomycotina|Rep: Contig An15c0240, complete genome -
Aspergillus niger
Length = 353
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 4/151 (2%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGD--PLWSARFLHTHPDEVVNTHLDFLIAGA-DLIITNTY 179
++LDGG T L H PLWS+ + + P +++ DF A D+++T TY
Sbjct: 7 LILDGGLGTSLQDHYNITFSSSTTPLWSSHLMISDPSTLLSCQRDFTTTAAVDVLLTATY 66
Query: 180 QASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYG 359
Q S EGF T+ S+ + +A R+ L+ VQN + + S+GPYG
Sbjct: 67 QVSPEGFQR----TKTPSHPTGIPRESIAGYLRTA-LDVAGQAVQNTSASVAL-SLGPYG 120
Query: 360 AHLHDGSEYDGSY-ADTTSVQTMRDWHRPRI 449
A + G EY G Y + + + + WH R+
Sbjct: 121 ACMIPGQEYSGKYDGEHDTEEKLWRWHTDRL 151
>UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 374
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/187 (29%), Positives = 86/187 (45%), Gaps = 24/187 (12%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVID-GDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+LDGG T L G V PLWS+ L + + + +F AGAD+++T TYQ S
Sbjct: 6 ILDGGLGTTLEDRFGVVFTHAKPLWSSDLLVSDQETLQACQREFAAAGADVLLTATYQVS 65
Query: 189 VEGFI-----EHL-GLTRKESYELIVR-AVELAKR---------ARSLYLEEYQDYVQND 320
VE F EH G+ + +R AVE+A++ A + + +
Sbjct: 66 VEAFARTKTPEHPDGIAPSSAMLPYLRGAVEIAEKAAAAAAAAAAAAAAAPRNETSAPSP 125
Query: 321 RVPLVVGSVGPYGAHLHDGSEYDGSY-ADTTSVQTMRDWHRPRIQALVEAGVDM------ 479
+ + + GPYGA + G EY G+Y A ++ + WH R+ AG D+
Sbjct: 126 QPAELALACGPYGAAMTPGQEYTGAYDAAHSTPDALSRWHLDRLALYAAAGEDVPGRCAY 185
Query: 480 LALETIP 500
+A ET+P
Sbjct: 186 VAFETVP 192
>UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein
NCU00799.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00799.1 - Neurospora crassa
Length = 361
Score = 63.7 bits (148), Expect = 2e-09
Identities = 57/181 (31%), Positives = 82/181 (45%), Gaps = 18/181 (9%)
Frame = +3
Query: 12 VLDGGFSTQLS-CHVGQVIDGDPLWSARFLHT-HPDEVVNTHLDFLIAGADLIITNTYQA 185
+LDGG T L H PLWS+ L + D++ + H F AGA++I T TYQ
Sbjct: 9 ILDGGMGTTLEDMHDITFSFETPLWSSHLLVSGEEDKLSDCHEAFKQAGANIISTATYQI 68
Query: 186 SVEGFI------------EHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVP 329
S+ GF E G+ ++E + RAV LA A +V
Sbjct: 69 SINGFAATKAPRSGTVDEEREGIEKEEIPRFLSRAVVLAANAAG----------TEGKVA 118
Query: 330 LVVGSVGPYGAHLHDGSEYDGSY-ADTTSVQTMRDWHRPRIQALVEAG---VDMLALETI 497
L S+GPYGA + +EY G Y + VQ + WH+ R+ + V+ +A ET+
Sbjct: 119 L---SLGPYGATMIPSTEYSGRYDPEHQHVQALGKWHKERLDLFKDVDPNQVNYIAFETV 175
Query: 498 P 500
P
Sbjct: 176 P 176
>UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Rep:
AFR410Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 370
Score = 58.8 bits (136), Expect = 6e-08
Identities = 51/171 (29%), Positives = 82/171 (47%), Gaps = 7/171 (4%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWS-ARFLHTHP---DEVVNTHLDFLIAGADLIITNT 176
+V+DGG +L V PLWS A FL D + + +F AG+ I T T
Sbjct: 60 LVMDGGMGVELERRGMDV--KSPLWSTAPFLRGDRAALDTIRGLYREFRAAGSRGISTLT 117
Query: 177 YQASVEGFIEHLG-LTRKESYE-LIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVG 350
YQAS +++ G ++ + YE + + V+ R ++ +DY+ +GSVG
Sbjct: 118 YQASFHSMVKYSGSVSSRADYEKFLEQVVDFTYRE---CVDPARDYI--------IGSVG 166
Query: 351 PYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQAL-VEAGVDMLALETIP 500
PY A L +G+EY G Y T ++ P++ + +D +A ET+P
Sbjct: 167 PYAAFLCNGAEYTGDYGFETI--NFFNYFEPQVSKFATDPRIDAIAFETVP 215
>UniRef50_A5UPF4 Cluster: Methionine synthase; n=4;
Chloroflexaceae|Rep: Methionine synthase - Roseiflexus
sp. RS-1
Length = 1254
Score = 55.6 bits (128), Expect = 6e-07
Identities = 54/166 (32%), Positives = 79/166 (47%), Gaps = 4/166 (2%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVID--GDPLWSAR--FLHTHPDEVVNTHLDFLIAGADLIITNT 176
++ DG T + D G+ + AR + T PD + H FL AGAD++ T T
Sbjct: 59 LIYDGAMGTSIDTFHLTAADYGGENTFGARDYLVMTRPDVIEQIHTSFLEAGADVLETCT 118
Query: 177 YQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPY 356
+Q S +E GL +++ + V A LA+R + E +D R V GS+GP
Sbjct: 119 FQ-STRIRLEEWGLA-DQTHAINVAAARLARRVADAF--EARD----GRPRYVAGSMGPT 170
Query: 357 GAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
G S D S +D T Q + D + AL+E GVD+L +ET
Sbjct: 171 GKL---PSSDDPSLSDITFDQ-LSDIFYEQAVALIEGGVDVLLVET 212
>UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 323
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/144 (25%), Positives = 71/144 (49%), Gaps = 1/144 (0%)
Frame = +3
Query: 72 DPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVR 251
D W + + + + + D++ +G+ ++ T TYQ S H + E Y+ ++R
Sbjct: 47 DDFWDSETKTSDRNIIEGIYRDYITSGSRILSTITYQTSFALISTHTEVKTIEGYKQLIR 106
Query: 252 AVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRD 431
+ RS E+ +Y ++GS+GP+GA L G+EY G+Y D+ S +
Sbjct: 107 --NITSFCRSAIGED--NY--------LIGSIGPFGARL--GAEYTGNYGDSPSNINYLE 152
Query: 432 WHRPRIQAL-VEAGVDMLALETIP 500
+ +P+++ +D++ ET+P
Sbjct: 153 YFKPQLEEFNNNDDIDIIGFETVP 176
>UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase,
putative; n=2; Trypanosoma cruzi|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma cruzi
Length = 410
Score = 52.8 bits (121), Expect = 4e-06
Identities = 55/195 (28%), Positives = 86/195 (44%), Gaps = 31/195 (15%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++ DG T L +WS+ L + D V H ++ AG D+++T TYQ
Sbjct: 10 LIKDGAMGTLLESWDVDYAKAGSMWSSSVLLSEMDLVKRAHRAYIDAGCDVLLTCTYQMH 69
Query: 189 VEGFIEHLGLTRKESYELIVRAVELA------------------KRARSLYLEEYQDYVQ 314
EG ++ EL+ RAV+ A K R+ ++ ++ +
Sbjct: 70 EEG----CAASKVTMCELVDRAVQAARHTMPQRKQKGLTEESTAKERRTGGIDVFRYALS 125
Query: 315 N------DRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQA-LVEAG- 470
+ +RV L+ GS+GPYG+ L G EY G Y+ +V + +H R++A L G
Sbjct: 126 SIKDNGQERVVLLAGSLGPYGSSLPGGQEYLGEYSIHEAV--INAFHARRLEAFLCNVGE 183
Query: 471 -----VDMLALETIP 500
VD L LET P
Sbjct: 184 KHAFKVDFLLLETFP 198
>UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 1231
Score = 52.4 bits (120), Expect = 6e-06
Identities = 38/132 (28%), Positives = 67/132 (50%), Gaps = 1/132 (0%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + + H +L AGAD+ TNT+ A+ +E G+ + + + + A +LA+
Sbjct: 57 TRPDVIKSIHRQYLDAGADIFATNTFNANAIS-MEDYGM-QGQVRNINLAAGKLAREVAD 114
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEY-DGSYADTTSVQTMRDWHRPRIQAL 458
+++E+ DR V GSVGP + D +Y T + + ++ ++ AL
Sbjct: 115 GFMKEHP-----DRTIFVAGSVGPTNKTASMSPDVSDPAYRAVTYLD-LYSAYKEQVDAL 168
Query: 459 VEAGVDMLALET 494
V+ GVD++ ET
Sbjct: 169 VDGGVDIVLFET 180
>UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Methylenetetrahydrofolate reductase - Herpetosiphon
aurantiacus ATCC 23779
Length = 617
Score = 52.0 bits (119), Expect = 7e-06
Identities = 53/162 (32%), Positives = 74/162 (45%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++ DG TQL G+ ID D + A L T PD V H ++ AGAD+I TNTY A+
Sbjct: 14 LLCDGAMGTQL---YGRGIDFDECFDALNL-TQPDVVREIHQSYIEAGADIIETNTYGAN 69
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
+E GL K ++ R ++LA+ AR + L+ G+VGP G L
Sbjct: 70 -RFKLEPFGLADKVR-QINHRGMKLAREAREI----------AGTNTLIAGAVGPLGVLL 117
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
Y T Q + +I L+E G D+L ET
Sbjct: 118 Q-------PYGPLTE-QAAHEAFAEQIGTLLEQGADLLMFET 151
>UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine
methyltransferase, truncation; n=8;
Desulfuromonadales|Rep:
5-methyltetrahydrofolate-homocysteine methyltransferase,
truncation - Geobacter sulfurreducens
Length = 804
Score = 51.6 bits (118), Expect = 1e-05
Identities = 43/131 (32%), Positives = 65/131 (49%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T P+ V H ++L AGAD+I+TNT+ S +EH GL + + E+ RAV +A+
Sbjct: 41 TLPEVVAGVHREYLDAGADIIVTNTFGGS-RAKLEHYGLQDRVA-EINARAVAIARE--- 95
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
V DR V S+GP G + D S+ + ++ R + QAL+
Sbjct: 96 ---------VCGDRA-YVAASIGPTGQFVEPVG--DVSFDEMAAI------FREQAQALI 137
Query: 462 EAGVDMLALET 494
AG D++ LET
Sbjct: 138 NAGADLITLET 148
>UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1;
Marinobacter sp. ELB17|Rep: Putative uncharacterized
protein - Marinobacter sp. ELB17
Length = 303
Score = 51.6 bits (118), Expect = 1e-05
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+LDGG ++ V LWS +H PD V H DF+ AGA + NTY A+
Sbjct: 5 VLLDGGLGQEIYRRAANV--SSALWSVAVMHEQPDVVTAVHSDFIRAGAKTLSLNTYAAT 62
Query: 189 V-----EGFIEHLGLTRKESYELIVRAVE 260
G +E L + ++EL+ +AV+
Sbjct: 63 PSRLLRHGQLEQLAAIHQNAFELLGQAVK 91
>UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25;
Cyanobacteria|Rep: Methionine synthase - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 1224
Score = 51.2 bits (117), Expect = 1e-05
Identities = 42/131 (32%), Positives = 62/131 (47%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T P+ V H FL GAD++ TNT+ A+ E+ G+ K +YEL V A LAKR +
Sbjct: 49 TKPEAVERVHRGFLEVGADVVETNTFGATSIVLAEY-GIPEK-AYELNVAAARLAKRVAA 106
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
++ ++ V GS+GP G S MR + ++Q LV
Sbjct: 107 -------EFATPEKPRFVAGSIGPTTKLPTLGH---------ISFDEMRAAYEEQVQGLV 150
Query: 462 EAGVDMLALET 494
+ G D+L +ET
Sbjct: 151 DGGADLLIIET 161
>UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:
Methionine synthase - Anaeromyxobacter sp. Fw109-5
Length = 1149
Score = 50.8 bits (116), Expect = 2e-05
Identities = 48/164 (29%), Positives = 73/164 (44%), Gaps = 2/164 (1%)
Frame = +3
Query: 9 VVLDGGFSTQLSCH--VGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
+V DG TQ+ H G + T PD V + H + G D++ TNT+
Sbjct: 12 LVFDGAMGTQIQRHQLTAAEFGGKDGANDLLTLTRPDLVEDIHARYFAVGCDVVETNTFG 71
Query: 183 ASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGA 362
+S ++ GL + +YE+ RA LA+RA + + D V GS+GP G
Sbjct: 72 SS-RLKLDEYGLGHR-TYEVNFRAAILARRAA-------ERFATPDHPRFVAGSMGPTGM 122
Query: 363 HLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
S D + + TS R + + + L+E GVD L +ET
Sbjct: 123 L---PSSSDPALGNITSDALERIFFE-QAKGLIEGGVDALIIET 162
>UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=1; Salinibacter ruber DSM 13855|Rep:
Vitamin B12-dependent methionine synthase family protein
- Salinibacter ruber (strain DSM 13855)
Length = 320
Score = 49.6 bits (113), Expect = 4e-05
Identities = 37/91 (40%), Positives = 46/91 (50%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+LDGG +L G LWSA L PD V H ++L AGAD+I TNTY
Sbjct: 13 VLLDGGLGQEL-IRRGMPSTEPSLWSANALTEAPDLVQEVHEEYLRAGADVITTNTYATP 71
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARS 281
E E GL + + L A LA+RAR+
Sbjct: 72 PERLSE-AGLDGR-AEALNREAGRLAERARA 100
>UniRef50_Q93A68 Cluster: Methylenetetrahydrofolate reductase; n=2;
Bacteria|Rep: Methylenetetrahydrofolate reductase -
uncultured bacterium
Length = 612
Score = 49.2 bits (112), Expect = 5e-05
Identities = 48/135 (35%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = +3
Query: 105 HPDEVVNTHLDFLIAGADLIITNTYQAS-VEGF-IEHLGLTRKESYELIVR---AVELAK 269
+PD V H ++ AGA LI TNTY A+ V F + G +Y L+ + EL +
Sbjct: 28 YPDTVRALHREYYEAGARLIETNTYTANRVRLFNLPERGSEAPPTYSLLEQFGSPEELVR 87
Query: 270 RARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRI 449
R + ++ V D LV GSVGP G L E T + R ++
Sbjct: 88 RINQEAVRLAREAVGAD--ALVFGSVGPVGKPLEPIGE--------TRLDEAEGAFREQM 137
Query: 450 QALVEAGVDMLALET 494
QAL+EAGVD L LET
Sbjct: 138 QALLEAGVDGLILET 152
>UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family
protein; n=6; Vibrionales|Rep: Homocysteine
S-methyltransferase family protein - Vibrio splendidus
12B01
Length = 299
Score = 49.2 bits (112), Expect = 5e-05
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
T +LDGG +L + PLWSA+ L P+ V H +F+ AGA+++ITN+Y
Sbjct: 3 TLTILDGGMGRELK-EIDAPFS-QPLWSAQALIEAPEFVSQAHQNFVDAGAEILITNSY- 59
Query: 183 ASVEGFIEHLG--LTRKESYELIVRAVELAK 269
A V HLG L + +EL ++ ELAK
Sbjct: 60 ACVP---FHLGEELFEQRGFELAAQSGELAK 87
>UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associated
KRAB repressor, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to RB-associated KRAB
repressor, partial - Ornithorhynchus anatinus
Length = 395
Score = 48.4 bits (110), Expect = 9e-05
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 4/152 (2%)
Frame = +3
Query: 54 GQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ----ASVEGFIEHLGLT 221
G+ + GDP + NTH D+L+AGAD+I TNT+ A + +EHL
Sbjct: 79 GRSLPGDPAPPTEEMKYDXXXXNNTH-DYLLAGADIIETNTFSGTRVAQADYGLEHL--- 134
Query: 222 RKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYA 401
+YEL + E+A+RA Q V G++GP L +
Sbjct: 135 ---AYELNRTSAEVARRAAD------DVAAQTGTKRFVAGALGPTNKTLSVSPSVERPDF 185
Query: 402 DTTSVQTMRDWHRPRIQALVEAGVDMLALETI 497
+ + + +R + + L++ GVD++ +ET+
Sbjct: 186 RNITFDELAEAYREQARGLLDGGVDIVLVETV 217
>UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1;
Pseudoalteromonas atlantica T6c|Rep: Homocysteine
S-methyltransferase - Pseudoalteromonas atlantica
(strain T6c / BAA-1087)
Length = 304
Score = 48.0 bits (109), Expect = 1e-04
Identities = 38/123 (30%), Positives = 58/123 (47%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
T +LDGG +L + D P+WSA + P+ V + H +F+ +GA +I NTY
Sbjct: 11 TITILDGGMGQELLRRSSR--DVTPMWSADIMLNEPELVRDLHREFINSGARVITLNTYT 68
Query: 183 ASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGA 362
A+ + L R+ +E V + A RA +E Q D V ++ GS+ P A
Sbjct: 69 ATPQ------RLKRENQFEQFVHLHDAAMRA----AQEAIALTQRDDV-MIAGSLPPLVA 117
Query: 363 HLH 371
H
Sbjct: 118 SYH 120
>UniRef50_Q1IQK2 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Acidobacteria bacterium
Ellin345|Rep: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 407
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/151 (29%), Positives = 68/151 (45%), Gaps = 16/151 (10%)
Frame = +3
Query: 93 FLHTHPDEVVNTHLDFLIAGADLIITNTYQAS----VEGFI----EHLGLTRKESYELIV 248
F T P + + H FL AGAD+I TNT+ A+ E F+ EH G + Y+ I+
Sbjct: 95 FSLTQPQMIGDIHRRFLEAGADIIETNTFGATSIVQSEFFVDDPREHGGRKDADFYQKII 154
Query: 249 RAVELAKRARSL------YLEEYQDYVQN--DRVPLVVGSVGPYGAHLHDGSEYDGSYAD 404
L A + E+ D V N R V G++GP L + + D
Sbjct: 155 DDQFLGDLAWEINETSAQQCREWADRVANATSRPRFVAGALGPLTVSLSNSPDADDPGFR 214
Query: 405 TTSVQTMRDWHRPRIQALVEAGVDMLALETI 497
+ ++ + +++AL+ GVD L +ETI
Sbjct: 215 VVTFDQVKIAYIQQVRALIAGGVDFLLVETI 245
>UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Plesiocystis pacifica SIR-1|Rep:
Homocysteine S-methyltransferase, putative -
Plesiocystis pacifica SIR-1
Length = 322
Score = 47.2 bits (107), Expect = 2e-04
Identities = 31/92 (33%), Positives = 52/92 (56%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LDG +T+L G ++ PL++AR L PD +V H D+ +AGA ++ TN++
Sbjct: 8 LLLDGALATELRRR-GFELEA-PLFAARALLEAPDLLVEIHRDYALAGAQVLSTNSFGLH 65
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSL 284
+ G+ +++ EL R+VEL AR L
Sbjct: 66 A-ATLARAGMAERQA-ELAARSVELTFLARQL 95
>UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma brucei
Length = 433
Score = 47.2 bits (107), Expect = 2e-04
Identities = 52/175 (29%), Positives = 75/175 (42%), Gaps = 34/175 (19%)
Frame = +3
Query: 78 LWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVR-- 251
+WS L T + V H +L GAD+I+TNTYQ G + G+T E VR
Sbjct: 48 MWSTSALITDEEIVRYVHKSYLDVGADVILTNTYQMHAAGCAQ-AGVTMNEVVNTAVRVL 106
Query: 252 --AVELAKRARSLYLEEYQDYVQNDR--------VP--------------LVVGSVGPYG 359
+ + A + + + +V N++ P LV GS+G YG
Sbjct: 107 CDGITPERAAATKEAKVWAQHVMNNKRSEFVNVFAPLFYGPRDDASKCPVLVGGSLGSYG 166
Query: 360 AHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV------EA--GVDMLALETIP 500
A L + EY G Y + +RD++ R A V EA VD + +ETIP
Sbjct: 167 ASLGNAQEYRGEYEVNEDI--IRDYYVGRFMAFVNHVDEKEAHLKVDFIMIETIP 219
>UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 1178
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/132 (27%), Positives = 61/132 (46%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD +++ H +L AGAD + TNT+ + ++ GL +Y L + E+AKRA
Sbjct: 43 TKPDAILDIHKGYLEAGADFVETNTFSGTKIAQADY-GL-EDAAYRLNRASAEVAKRA-- 98
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
Y+ V G++GP L + + + D + + + L+
Sbjct: 99 ----AYEVTASTGVEKFVAGAMGPTNRTLSISPTVECPGFRNVTFDELVDAYTEQARGLL 154
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 155 DGGVDVLLVETI 166
>UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to
5-methyltetrahydrofolate:homocysteine methyltransferase;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to 5-methyltetrahydrofolate:homocysteine
methyltransferase - Strongylocentrotus purpuratus
Length = 172
Score = 46.4 bits (105), Expect = 4e-04
Identities = 18/29 (62%), Positives = 25/29 (86%)
Frame = +3
Query: 414 VQTMRDWHRPRIQALVEAGVDMLALETIP 500
++ ++ WHRPRIQALV+ VD+LA+ETIP
Sbjct: 3 MRELKQWHRPRIQALVDGKVDLLAIETIP 31
>UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium
nucleatum|Rep: Methionine synthase - Fusobacterium
nucleatum subsp. polymorphum ATCC 10953
Length = 1082
Score = 46.4 bits (105), Expect = 4e-04
Identities = 35/132 (26%), Positives = 64/132 (48%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++ AGAD+I TN++ + ++ K+ Y L + +LAK++
Sbjct: 46 TRPDIIFEVHKKYIEAGADIIETNSFNCN--------AISLKD-YHLEDKVYDLAKKSAE 96
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
+ + + ++ + V GS+GP L D Y S M++ + ++ L+
Sbjct: 97 IARDAVK---ESGKKVYVFGSIGPTNKSL-SFPVGDVPYKRAVSFDEMKEVIKVQVAGLI 152
Query: 462 EAGVDMLALETI 497
+ GVD + LETI
Sbjct: 153 DGGVDGILLETI 164
>UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 306
Score = 46.4 bits (105), Expect = 4e-04
Identities = 30/86 (34%), Positives = 42/86 (48%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDGG +L PLWS + + P+ V N H DF +AGA +I NTY SV
Sbjct: 7 LLDGGMGQEL-IRRSSAAKPHPLWSLQVMMDEPELVANVHRDFCLAGARVICLNTY--SV 63
Query: 192 EGFIEHLGLTRKESYELIVRAVELAK 269
+G + EL+ A +LA+
Sbjct: 64 TRHRLQMGNELPDLPELLKHAGDLAR 89
>UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9;
Saccharomycetaceae|Rep: Homocysteine S-methyltransferase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 325
Score = 46.4 bits (105), Expect = 4e-04
Identities = 48/176 (27%), Positives = 82/176 (46%), Gaps = 12/176 (6%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSA-RFLHTH--PDE-------VVNTHLDFLIAGAD 158
+VLDGG T+L +V +P+WS F+ DE V DFL AGA+
Sbjct: 18 LVLDGGQGTELENRGIKV--ANPVWSTIPFISESFWSDESSANRKIVKEMFNDFLNAGAE 75
Query: 159 LIITNTYQASVEGFIEHLGL-TRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLV 335
+++T TYQ S + E+ + T E L+ R V+ ++ + D+ +
Sbjct: 76 ILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFSRNC-----------IGEDK--YL 122
Query: 336 VGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAG-VDMLALETIP 500
+G +GP+GAH+ E+ G Y + +P+++ + +D++ ETIP
Sbjct: 123 IGCIGPWGAHI--CREFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIP 176
>UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;
Schizosaccharomyces pombe|Rep: Uncharacterized protein
C57A7.07c - Schizosaccharomyces pombe (Fission yeast)
Length = 308
Score = 46.0 bits (104), Expect = 5e-04
Identities = 46/171 (26%), Positives = 82/171 (47%), Gaps = 7/171 (4%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LDGG ST + + + I LW++ L +P+ VV H +FL D+I T TYQ
Sbjct: 2 LMLDGG-STAILPKLPESISESRLWTSEALVRYPEIVVKHHEEFLKV-CDIISTFTYQLD 59
Query: 189 VEGFIEHL-GLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAH 365
+ E + G+ K+ Y ++ L +Y E+ + N + L +GS + A
Sbjct: 60 ASIYDEKVEGVPLKQVY---ANSIGL-----PVYAREHLG-LPNKYIALCLGS---HAAT 107
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAG------VDMLALETIP 500
+ EY Y T + + ++H+ RI+A+ + +D +A E++P
Sbjct: 108 IPGCMEYKMIYDKPTDFEMLYNFHKNRIEAIQASNPKAFEKIDFIAFESLP 158
>UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Rep:
Mlr1281 protein - Rhizobium loti (Mesorhizobium loti)
Length = 301
Score = 45.6 bits (103), Expect = 6e-04
Identities = 25/62 (40%), Positives = 34/62 (54%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++ DGG +L + PLWSAR L PD V + H +F+ AGA +I NTY A+
Sbjct: 5 ILTDGGMGQELVRRSKS--EPTPLWSARVLIDEPDLVRDLHAEFIRAGARVITINTYSAT 62
Query: 189 VE 194
E
Sbjct: 63 PE 64
>UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2;
Gammaproteobacteria|Rep: Homocysteine
S-methyltransferase - Psychromonas ingrahamii (strain
37)
Length = 310
Score = 45.6 bits (103), Expect = 6e-04
Identities = 36/115 (31%), Positives = 55/115 (47%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LDGG +L +G P WSA+ L P + H F+ AGA++I TNTY +
Sbjct: 17 IILDGGMGRELK-RIGAPFQ-QPEWSAQALIESPHFISEVHKSFIEAGAEVITTNTY--A 72
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGP 353
+ F H+G K E ++LA R ++E + +P V+GS P
Sbjct: 73 LVPF--HIG--EKRFNEQGADLIKLAARLARECVKENSAVLVAGCIPPVLGSYRP 123
>UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Homocysteine S-methyltransferase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 411
Score = 45.2 bits (102), Expect = 8e-04
Identities = 47/163 (28%), Positives = 75/163 (46%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
+V DG TQL + + + LWS T P+ + H D+ AG+D + TNT+ A+
Sbjct: 11 LVFDGAMGTQLIQNGLKENECPDLWSV----TRPEVIAKIHRDYFEAGSDCVETNTFGAN 66
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
E ++ GL E ++ A+ LAK +EY YV SVGP G +
Sbjct: 67 REK-LKKYGL-ENEVEKINKAAILLAKDV----AKEYGGYVGL--------SVGPTGRLM 112
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETI 497
+ D A++ + +I A +EAG D +++ET+
Sbjct: 113 RPSGDLDFDEAESVFYE--------QILAGIEAGADFISIETM 147
>UniRef50_Q99707 Cluster: Methionine synthase; n=268; cellular
organisms|Rep: Methionine synthase - Homo sapiens
(Human)
Length = 1265
Score = 45.2 bits (102), Expect = 8e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=8; Cyanobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Prochlorococcus marinus
Length = 1182
Score = 44.0 bits (99), Expect = 0.002
Identities = 39/131 (29%), Positives = 62/131 (47%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T+P V N H +L G D+I TNT+ A+ +E L K +YE+ + A LAK
Sbjct: 51 TNPQAVRNVHRSYLEVGCDVIETNTFGAT-SIVLEEYNLQDK-TYEINLEAARLAKGI-- 106
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
+++ +D+ V GSVGP G S + ++ +I+AL+
Sbjct: 107 -----VKEFSTDDKPRFVAGSVGPTTKLPTLGH---------ISFDKLSSSYQEQIEALI 152
Query: 462 EAGVDMLALET 494
+ VD++ LET
Sbjct: 153 DGEVDLILLET 163
>UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=2;
Acidobacteria|Rep: Methylenetetrahydrofolate reductase -
Acidobacteria bacterium (strain Ellin345)
Length = 617
Score = 44.0 bits (99), Expect = 0.002
Identities = 38/131 (29%), Positives = 65/131 (49%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
+ P+ + H D++ GA+++ TNT+ A+ H G K + ++ VEL ++A
Sbjct: 41 SQPELIGGIHADYVANGAEILETNTFGANSFRLARH-GCQEKLA-DINRAGVELVRKA-- 96
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
++N++V G+VGP G + + TS RD R +I+ LV
Sbjct: 97 ---------IKNNQV-YAAGAVGPLGIRIEPLGK--------TSRDEARDAFRDQIRVLV 138
Query: 462 EAGVDMLALET 494
++GVD+L LET
Sbjct: 139 DSGVDLLILET 149
>UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5;
Alphaproteobacteria|Rep: Homocysteine
S-methyltransferase - Dinoroseobacter shibae DFL 12
Length = 350
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/56 (42%), Positives = 29/56 (51%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTY 179
+LDGG +L G+ PLWS L PD V H DF AGA++ TNTY
Sbjct: 47 LLDGGLGQELVRRAGRAT---PLWSMEALLNAPDLVRAVHDDFFAAGAEVATTNTY 99
>UniRef50_P74718 Cluster: Slr1189 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Slr1189 protein - Synechocystis sp.
(strain PCC 6803)
Length = 351
Score = 43.2 bits (97), Expect = 0.003
Identities = 48/170 (28%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHP---DEVVNTHLDFLIAGAD-----LII 167
+LDGG T++ + G + P ++A L + P + + N FL + LI
Sbjct: 51 LLDGGLETEMIFNRGFDL---PAFAAHTLLSDPLGREALKNYFHGFLDLAKEKQFGFLID 107
Query: 168 TNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSV 347
T++A F E LG++ +E + RAVE A+ + Y+ E Q + N G +
Sbjct: 108 APTWRAQ-PFFAEELGVSLEEIRQANFRAVEFARALKQAYVNEIQPLLIN-------GLI 159
Query: 348 GPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETI 497
GP G Y G + ++ + + +HR +I L EAGVD+L T+
Sbjct: 160 GPCG------DAYGGEHF--SNAEAAQVYHRQQISWLAEAGVDLLGAFTL 201
>UniRef50_Q2AGF5 Cluster: Dihydropteroate synthase,
DHPS:Homocysteine S- methyltransferase:Methionine
synthase, B12-binding module, cap:Cobalamin B12-binding;
n=1; Halothermothrix orenii H 168|Rep: Dihydropteroate
synthase, DHPS:Homocysteine S-
methyltransferase:Methionine synthase, B12-binding
module, cap:Cobalamin B12-binding - Halothermothrix
orenii H 168
Length = 819
Score = 43.2 bits (97), Expect = 0.003
Identities = 41/130 (31%), Positives = 61/130 (46%)
Frame = +3
Query: 108 PDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLY 287
PD + H +++ AGA LI TNT+ A+ ++ LGL K E+ V+A LA++A
Sbjct: 43 PDTIYKIHKEYVAAGAGLIETNTFGAN-RLKLKSLGLEDKIE-EINVKATGLARKAAGKV 100
Query: 288 LEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEA 467
V GSVGP G + + S RD + +I LV A
Sbjct: 101 --------------FVAGSVGPTGKLMEPHGD--------LSFDRARDVFKEQISYLVHA 138
Query: 468 GVDMLALETI 497
GVD++ +ET+
Sbjct: 139 GVDVVIIETM 148
>UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1;
Desulfotomaculum reducens MI-1|Rep: Homocysteine
S-methyltransferase - Desulfotomaculum reducens MI-1
Length = 800
Score = 42.7 bits (96), Expect = 0.004
Identities = 43/132 (32%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIE-HLGLTRKESYELIVRAVELAKRAR 278
+HP+ V H +L AGAD+I TNT+ A + HLG KE + AV+LAK
Sbjct: 39 SHPEAVKEIHKLYLEAGADIITTNTFGAIQLKLADYHLGDQVKEINQ---AAVKLAKEVA 95
Query: 279 SLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQAL 458
Y +V GSVGP G L T + + + A+
Sbjct: 96 QPY------------GAMVAGSVGPLGKFLQP--------LGTMTFEEAYQQFYEQCAAM 135
Query: 459 VEAGVDMLALET 494
VEAGVD++ ET
Sbjct: 136 VEAGVDLILFET 147
>UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 176
Score = 42.3 bits (95), Expect = 0.006
Identities = 49/159 (30%), Positives = 70/159 (44%), Gaps = 1/159 (0%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
VV DG L G V+ G W+ +PD V H +FL AGAD+I T TY A+
Sbjct: 22 VVGDGSMLITLEKR-GYVMAGS--WTPEATLQYPDAVKQLHREFLRAGADVIQTFTYCAT 78
Query: 189 VEGFIEHLGLTRKESYEL-IVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAH 365
E ++ K S ++ V E+ RA L E V N+ LV GSV A+
Sbjct: 79 -EDNLKMKNEHEKNSNDMKSVSVSEINHRACDLARE-----VANEGGALVAGSVSNVNAY 132
Query: 366 LHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDML 482
DG+ + +++ + + LV+ GVD L
Sbjct: 133 RKDGA------CHGAGKEFVQNEFKKQCDILVKKGVDFL 165
>UniRef50_Q6AL45 Cluster: Related to
5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Desulfotalea psychrophila|Rep:
Related to 5-methyltetrahydrofolate--homocysteine
methyltransferase - Desulfotalea psychrophila
Length = 316
Score = 42.3 bits (95), Expect = 0.006
Identities = 48/164 (29%), Positives = 79/164 (48%), Gaps = 2/164 (1%)
Frame = +3
Query: 9 VVLDGGFSTQL-SCHVGQVIDGDPLWSARFLH-THPDEVVNTHLDFLIAGADLIITNTYQ 182
++ DG T L S ++ GD FL+ + P+ ++ H FL AGA ++ TNT+
Sbjct: 9 LIFDGACGTTLQSMNIAPSAWGDLAGCNEFLNISAPEYIIELHKKFLEAGAMVVETNTFG 68
Query: 183 ASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGA 362
AS E+ GL K E+ AV+ AK+A + + +D + + + GS+GP
Sbjct: 69 ASSIVLTEY-GLENKVD-EINREAVKNAKKA----ISQLKD---SSQPRYIAGSIGP--- 116
Query: 363 HLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
G Q++R+ ++ +L+EAGVD L +ET
Sbjct: 117 --TTKLPSLGHIETKVLAQSIRE----QVISLLEAGVDALIVET 154
>UniRef50_Q024B4 Cluster: Homocysteine S-methyltransferase; n=1;
Solibacter usitatus Ellin6076|Rep: Homocysteine
S-methyltransferase - Solibacter usitatus (strain
Ellin6076)
Length = 304
Score = 42.3 bits (95), Expect = 0.006
Identities = 46/159 (28%), Positives = 69/159 (43%)
Frame = +3
Query: 18 DGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEG 197
DG TQL + + LW+ THP+ V+ + AG+D I+TNT+ S
Sbjct: 17 DGAMGTQLMFAGLEQGNCGELWNL----THPERVLGIQRRYAEAGSDCILTNTFGGSRIM 72
Query: 198 FIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDG 377
H G + K E+ AVE+A+ A R V+G +GP+G +
Sbjct: 73 LNRH-GSSGK-VVEINRAAVEIAREA------------FGGRAGYVIGDIGPFGGLMQ-- 116
Query: 378 SEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
Y D T + +R + ALV+AG D + +ET
Sbjct: 117 -----PYGDFTE-EDVRSAFGEQAGALVDAGADAIIIET 149
>UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:
Methionine synthase - Solibacter usitatus (strain
Ellin6076)
Length = 1185
Score = 42.3 bits (95), Expect = 0.006
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 1/132 (0%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + + H +L AGAD+I TNT+ + ++ + +YEL A +LA+
Sbjct: 54 TRPDVIQDIHRQYLEAGADIIETNTFGGTRIALADN--KLEERAYELNFAAAKLAR---- 107
Query: 282 LYLEEYQDYVQNDRVP-LVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQAL 458
E D P V GS+GP + D + +T+ ++ + + + L
Sbjct: 108 ----EVADQFSTAAKPRFVAGSIGP--------TNKDLNITGSTTFPEIKAAYYEQAKGL 155
Query: 459 VEAGVDMLALET 494
VE G D L +ET
Sbjct: 156 VEGGADYLLIET 167
>UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1;
Vibrio harveyi ATCC BAA-1116|Rep: Putative
uncharacterized protein - Vibrio harveyi ATCC BAA-1116
Length = 301
Score = 42.3 bits (95), Expect = 0.006
Identities = 22/56 (39%), Positives = 31/56 (55%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTY 179
+LDGG +L PLWSA+ L P+ V H +F+ AGA++II N+Y
Sbjct: 6 ILDGGMGRELKRMSAPF--SQPLWSAQALIESPEFVYQAHDNFIQAGAEIIIANSY 59
>UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Alteromonas macleodii 'Deep ecotype'|Rep:
Homocysteine S-methyltransferase family protein -
Alteromonas macleodii 'Deep ecotype'
Length = 305
Score = 42.3 bits (95), Expect = 0.006
Identities = 32/90 (35%), Positives = 48/90 (53%), Gaps = 2/90 (2%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDGG +L +G P WSA L P+ V + H FL AGA +I TNTY ++
Sbjct: 10 ILDGGMGRELK-KIGAPFR-QPEWSALALMQSPELVSDVHTHFLNAGATVITTNTY--AL 65
Query: 192 EGFIEHLG--LTRKESYELIVRAVELAKRA 275
F H+G +++++L A +LA+ A
Sbjct: 66 VPF--HIGEQTFNEQAFKLAETAAKLARDA 93
>UniRef50_A7DNT5 Cluster: Homocysteine S-methyltransferase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Homocysteine S-methyltransferase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 320
Score = 42.3 bits (95), Expect = 0.006
Identities = 36/131 (27%), Positives = 61/131 (46%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H +L AGAD I TN++ ++ + + Y + +E K+
Sbjct: 50 TRPDWIKQIHRHYLDAGADCIETNSFGSN---------KIKLDEYGFGDQTIEFNKKIAQ 100
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
L E Q+Y +DR V+GS+GP G L ++ D + +++ + + L+
Sbjct: 101 LASEVCQEY--SDRPRYVIGSMGPSG-FLPSSNDPD---LGQKPLDEIKEAFELQAEGLI 154
Query: 462 EAGVDMLALET 494
GVD L +ET
Sbjct: 155 LGGVDALLIET 165
>UniRef50_Q55786 Cluster: Methionine synthase; n=5;
Cyanobacteria|Rep: Methionine synthase - Synechocystis
sp. (strain PCC 6803)
Length = 1195
Score = 42.3 bits (95), Expect = 0.006
Identities = 37/133 (27%), Positives = 62/133 (46%)
Frame = +3
Query: 96 LHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRA 275
+HT P+ V H F AGAD++ T+T+ + E+ +SY L A ELAK
Sbjct: 50 VHTKPEAVATVHRAFYEAGADVVETDTFGGTPLVLAEY--DLADQSYYLNKAAAELAKAV 107
Query: 276 RSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQA 455
+ ++ ++ V GS+GP G L D +++D + +++
Sbjct: 108 AA-------EFSTPEKPRFVAGSMGP-GTKLPTLGHVD--------YDSLKDAYVVQVRG 151
Query: 456 LVEAGVDMLALET 494
L + GVD+L +ET
Sbjct: 152 LYDGGVDLLLVET 164
>UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=21; Bacteria|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Bacillus halodurans
Length = 1146
Score = 41.5 bits (93), Expect = 0.010
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 4/166 (2%)
Frame = +3
Query: 9 VVLDGGFSTQLSCH--VGQVIDGDPLWSAR-FLH-THPDEVVNTHLDFLIAGADLIITNT 176
V+LDG T L G+ +L+ T P V + H +L AGAD+I TNT
Sbjct: 15 VILDGAMGTMLQAANLTADDFGGEEYEGCNEYLNETAPHVVEDIHRAYLEAGADVIATNT 74
Query: 177 YQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPY 356
+ A+ + ++ L K + EL + AV++AKR +++ D V G++GP
Sbjct: 75 FGAT-DIVLDDYDLGYK-AEELNICAVKIAKRVA-------EEFSTPDWPRFVAGAMGPT 125
Query: 357 GAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
L S + + + + +R + L++ G D+L LET
Sbjct: 126 TKSL--------SVTGGATFEQLIESYRQQATGLIKGGADILLLET 163
>UniRef50_A7CWS4 Cluster: Homocysteine S-methyltransferase
precursor; n=7; Bacteria|Rep: Homocysteine
S-methyltransferase precursor - Opitutaceae bacterium
TAV2
Length = 398
Score = 41.5 bits (93), Expect = 0.010
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 1/133 (0%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H + AGAD++ TNT+ ++ ++ E +V + A A +
Sbjct: 98 TRPDVIEGIHAAYFAAGADMVETNTFNSTAISQADY-------HLEPLVTEINTAAAAIA 150
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYD-GSYADTTSVQTMRDWHRPRIQAL 458
+ R V G++GP L + + Y T Q + + +I+AL
Sbjct: 151 RRAVRATETATPGRRCFVAGAIGPLNRTLSMSPDVNRPDYRAVTWAQVVAA-YTEQIRAL 209
Query: 459 VEAGVDMLALETI 497
+ GVD L +ETI
Sbjct: 210 IAGGVDALLVETI 222
>UniRef50_Q4WFR2 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Trichocomaceae|Rep: Homocysteine
S-methyltransferase, putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 313
Score = 41.1 bits (92), Expect = 0.014
Identities = 36/121 (29%), Positives = 67/121 (55%), Gaps = 5/121 (4%)
Frame = +3
Query: 150 GADLII-TNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRV 326
G +++ T T++ + + + +GL+ + EL AV LAK AR+ + + +
Sbjct: 63 GTGIVLDTRTWRGATP-WAQPMGLSADKLLELNRAAVRLAKEARNRAVGG------ENNI 115
Query: 327 PLVV-GSVGPYGAHLHDGSEYDGSYADTTSVQTM---RDWHRPRIQALVEAGVDMLALET 494
P+V+ G++GP L D +Y DT+ + T+ R+ +R +++ L +AGVDMLA+ T
Sbjct: 116 PVVISGTMGP----LRD------AYVDTSELITLEDAREGYREQVEVLADAGVDMLAIMT 165
Query: 495 I 497
+
Sbjct: 166 V 166
>UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransferase
family protein; n=1; uncultured alpha proteobacterium
EBAC2C11|Rep: Putative homocysteine S-methyltransferase
family protein - uncultured alpha proteobacterium
EBAC2C11
Length = 309
Score = 40.7 bits (91), Expect = 0.018
Identities = 20/60 (33%), Positives = 35/60 (58%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++LD G ST+L ++ +G WS +++V TH+ ++ AGAD+I N+Y +S
Sbjct: 18 IILDSGVSTELERRGAKMRNGQ--WSGCVAIDDYEKLVETHIAYIEAGADIITVNSYASS 75
>UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Lentisphaera araneosa
HTCC2155|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Lentisphaera araneosa HTCC2155
Length = 1204
Score = 40.7 bits (91), Expect = 0.018
Identities = 53/188 (28%), Positives = 87/188 (46%), Gaps = 26/188 (13%)
Frame = +3
Query: 9 VVLDG--GFSTQLSCHVGQVIDGDP--LWSARFLHTHPDEVV-NTHLDFLIAGADLIITN 173
+VLDG G QL G+ + S + + PD+V N HL++L AGA+++ TN
Sbjct: 12 LVLDGAMGSMVQLLKLPDSAYGGEEYAMLSDLLVFSRPDQVRDNIHLEYLKAGANILETN 71
Query: 174 TYQAS-------------VEGFI---EHLGLTRKESYELI----VRAVELAKRARSLYLE 293
T+ AS + F E L + Y L +R +ELA+ A +E
Sbjct: 72 TFGASPLRLQEFDFSKMDLSDFADLPEGLDFLENDYYALTHYFNIRGIELAQDA----IE 127
Query: 294 EYQDYVQNDRVPL-VVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAG 470
+Y+ + D PL V GS+GP + + + T T++ +++A+++A
Sbjct: 128 KYKKMDEYDGRPLFVAGSIGPSNWVISS----TAANLNKTDFATIKQNFYLQVKAMMQAN 183
Query: 471 VDMLALET 494
VD+L ET
Sbjct: 184 VDVLLFET 191
>UniRef50_A0RW49 Cluster: Methionine synthase I
(Cobalamin-dependent), methyltransferase domain; n=1;
Cenarchaeum symbiosum|Rep: Methionine synthase I
(Cobalamin-dependent), methyltransferase domain -
Cenarchaeum symbiosum
Length = 317
Score = 40.3 bits (90), Expect = 0.024
Identities = 39/143 (27%), Positives = 67/143 (46%)
Frame = +3
Query: 66 DGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELI 245
DG ++ + + P+ + H ++ AGAD I TN++ ++ + + Y
Sbjct: 38 DGKEGFNDGLVLSRPEWISKIHRSYIEAGADCIETNSFGSN---------KIKLDEYGFG 88
Query: 246 VRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTM 425
R VE+ ++A SL E V+ D VVGS+GP G +L ++ D + T+
Sbjct: 89 ERTVEINEKAASLAAAE-AGRVERD--VYVVGSMGPTG-YLPSSNDPD---LGQIPLDTI 141
Query: 426 RDWHRPRIQALVEAGVDMLALET 494
+D + + LV G D L +ET
Sbjct: 142 QDAFALQAEGLVRGGADALIIET 164
>UniRef50_Q748M7 Cluster: Methylenetetrahydrofolate reductase; n=8;
Desulfuromonadales|Rep: Methylenetetrahydrofolate
reductase - Geobacter sulfurreducens
Length = 605
Score = 39.9 bits (89), Expect = 0.031
Identities = 42/129 (32%), Positives = 57/129 (44%)
Frame = +3
Query: 108 PDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLY 287
P V+ H ++L AGA +I TNT+ A+ + +GL +KE E+ +R +LA+ A
Sbjct: 41 PSLVLELHREYLAAGARVIETNTFGANWTR-LAAIGLEKKER-EINLRGAQLAREAAQ-- 96
Query: 288 LEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEA 467
V GSVGP D E S Q D R + AL E
Sbjct: 97 ----------GTDAFVAGSVGPLVRMKGDEQEL--------SAQETVDIFRRQTHALAEG 138
Query: 468 GVDMLALET 494
VD+L LET
Sbjct: 139 EVDLLILET 147
>UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Prochlorococcus marinus str. MIT
9211|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Prochlorococcus marinus str. MIT
9211
Length = 1191
Score = 39.9 bits (89), Expect = 0.031
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 7/171 (4%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARF-------LHTHPDEVVNTHLDFLIAGADL 161
T +V DGG T L Q + + ++F L ++P V H +L G D+
Sbjct: 12 TILVFDGGMGTALQL---QELSKEDFGGSQFEGCNEYLLISNPKSVEKVHRSYLEVGCDV 68
Query: 162 IITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVG 341
I TNT+ A+ E+ GL K +Y+L + A ++AK ++Y ++ G
Sbjct: 69 IETNTFGATSVVLAEY-GLENK-AYQLNLAASKMAKTLA-------KEYSTINKPRYAAG 119
Query: 342 SVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALET 494
S+GP L D + D T+ ++ +++AL+ G+D++ +ET
Sbjct: 120 SIGP-TTKLPTLGHID--FDDLTNS------YQEQVEALITGGIDLVLVET 161
>UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;
Proteobacteria|Rep: Homocysteine S-methyltransferase -
Psychrobacter sp. PRwf-1
Length = 310
Score = 39.5 bits (88), Expect = 0.042
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
++DGG +L+ P WSA + P+ V + H DF+ +GA +I TN+Y ++
Sbjct: 8 IIDGGMGRELAKRGAPF--RQPEWSALAMIEAPEIVRDVHRDFIRSGAGVITTNSY--AL 63
Query: 192 EGFIEHLGLTR--KESYELIVRAVELAKRARSL 284
F H+G R K + +L A E+A+ A L
Sbjct: 64 LPF--HIGEVRFAKHAQDLAASAGEMARAAVEL 94
>UniRef50_Q9I2Q2 Cluster: Methionine synthase; n=95; Bacteria|Rep:
Methionine synthase - Pseudomonas aeruginosa
Length = 1234
Score = 39.5 bits (88), Expect = 0.042
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 96 LHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRA 275
L + PD + +L AGAD++ TNT+ A+ ++ G+ + +YEL V LA++
Sbjct: 64 LLSRPDVIQAIEKAYLDAGADILETNTFNATQVSQADY-GM-QSLAYELNVEGARLARQV 121
Query: 276 RSLYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDG-SYADTTSVQTMRDWHRPRIQ 452
E D+ V G +GP + + Y + T + + ++ +
Sbjct: 122 ADAKTAE-----TPDKPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVE-ATR 175
Query: 453 ALVEAGVDMLALETI 497
L+E G D++ +ETI
Sbjct: 176 GLIEGGADLILIETI 190
>UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=1;
Lactobacillus plantarum|Rep: Methylenetetrahydrofolate
reductase - Lactobacillus plantarum
Length = 618
Score = 39.1 bits (87), Expect = 0.055
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQAS 188
THPD ++ H ++ AGAD+I TNTY A+
Sbjct: 38 THPDTILRVHRSYIRAGADIIQTNTYAAN 66
>UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 508
Score = 39.1 bits (87), Expect = 0.055
Identities = 17/55 (30%), Positives = 35/55 (63%)
Frame = +3
Query: 123 NTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLY 287
N HL +L+AG ++I TNT+Q ++ ++ G++ ++ ++ R +++A RA Y
Sbjct: 44 NIHLSYLLAGCNVISTNTFQVNLHS-LQEKGISVQDGEGIVDRYIDIAHRALLRY 97
>UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella
succinogenes|Rep: S-METHYLTRANSFERASE - Wolinella
succinogenes
Length = 1120
Score = 38.7 bits (86), Expect = 0.073
Identities = 36/131 (27%), Positives = 60/131 (45%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T D +++ H +L AGAD++ +NT+ A + +E G+ + +YE+ ++AK
Sbjct: 48 TRGDVILSIHRSYLEAGADILKSNTFGA-LPWVLEEYGIGGR-AYEMAFAGAQIAK---- 101
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
E + + R V GS+GP G L D TM + ++ + L
Sbjct: 102 ---EACDSFAPSPR--FVAGSLGP-GTKLPSLGHID--------YDTMFEGYKEAARGLK 147
Query: 462 EAGVDMLALET 494
E G D+ LET
Sbjct: 148 EGGADLFLLET 158
>UniRef50_Q9WYU7 Cluster: Putative uncharacterized protein; n=2;
Thermotoga|Rep: Putative uncharacterized protein -
Thermotoga maritima
Length = 417
Score = 38.3 bits (85), Expect = 0.096
Identities = 36/114 (31%), Positives = 50/114 (43%)
Frame = +3
Query: 132 LDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYV 311
LD + GA S G+ HL LT K+ E +V + A A S+YL E Q Y
Sbjct: 172 LDATLFGAFYDTDTNNATSAYGYAAHLNLTGKDILENLVVDLAYAYEATSMYLVEAQ-YS 230
Query: 312 QNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGV 473
++ + V +V PY + SE +Y D SV W P LV+ G+
Sbjct: 231 KSFEMEPVTLTVSPYFVY----SEGAPTYYDDDSVDG-DGWTAPWGSKLVKVGL 279
>UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3;
Bacteria|Rep: Homocysteine S-methyltransferase -
Pelagibacter ubique
Length = 302
Score = 38.3 bits (85), Expect = 0.096
Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARFL--HTHPDEVVNTHLDFLIAGADLIITNT 176
T +LDGG +L G +G LWSA + + +++THLDF+ AGA++I+T T
Sbjct: 8 TTRILDGGMGQELLAR-GMKPNGT-LWSANAVLKEEYHQLLLDTHLDFIKAGAEVIVTAT 65
Query: 177 Y 179
+
Sbjct: 66 F 66
>UniRef50_A6QBA6 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Sulfurovum sp. (strain NBC37-1)
Length = 1169
Score = 38.3 bits (85), Expect = 0.096
Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 5/102 (4%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T D + H + +AGADLI TNT+ G + + + Y++ RA EL+K+
Sbjct: 54 TAADLIKRIHKRYAMAGADLIKTNTF-----GTMPWV----LDEYQMGERAYELSKKGAE 104
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYG-----AHLHDGSEYDG 392
L E +Y V+GS+GP H+H Y+G
Sbjct: 105 LVKEICAEYSTKISPKFVLGSIGPGTKLPSLGHIHYDEMYEG 146
>UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep:
Methionine synthase - Magnetococcus sp. (strain MC-1)
Length = 1220
Score = 38.3 bits (85), Expect = 0.096
Identities = 30/132 (22%), Positives = 57/132 (43%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T P + N H +L AGAD++ TNT+ + ++ GL YE+ + +A++A
Sbjct: 63 TKPQVIRNIHTAYLEAGADIVETNTFNGNAPSLGDY-GL-EALVYEVNLEGARVARQACD 120
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
+ + Q R+ V G +GP + + + + + L+
Sbjct: 121 AVMAQ-----QPGRICFVAGVLGPTNRTCSISPDVNNPGFRNIDFDALVADYANGTRGLL 175
Query: 462 EAGVDMLALETI 497
+ G D+L +ET+
Sbjct: 176 DGGADILLVETV 187
>UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family
protein; n=9; Rhodobacteraceae|Rep: Homocysteine
S-methyltransferase family protein - Silicibacter
pomeroyi
Length = 298
Score = 37.9 bits (84), Expect = 0.13
Identities = 29/92 (31%), Positives = 44/92 (47%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDG +L G+ PLWS + P V H D+ AGA + TNTY A +
Sbjct: 6 LLDGSIGQELVKRAGK--RPTPLWSTSVMLEAPYHVGAVHRDYFDAGATIATTNTY-AVL 62
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRARSLY 287
+E G+ + LI A++ A+ AR+ +
Sbjct: 63 RDRLEPAGIGDRFE-ALIDTALDQAESARAAH 93
>UniRef50_Q8DCJ7 Cluster: Methionine synthase; n=51; Bacteria|Rep:
Methionine synthase - Vibrio vulnificus
Length = 1226
Score = 37.9 bits (84), Expect = 0.13
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 1/133 (0%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T P + H +L AGAD++ TNT+ A+ ++ S E+ A LA+ A
Sbjct: 60 TQPQLIKEIHHAYLEAGADILETNTFNATTIAMADY--DMESLSEEINFAAARLAREA-- 115
Query: 282 LYLEEYQDYVQNDRVP-LVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQAL 458
+E+ QN P V G +GP + + S + + + +AL
Sbjct: 116 --ADEWT--AQNPAKPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVEAYSESTRAL 171
Query: 459 VEAGVDMLALETI 497
+ G D++ +ETI
Sbjct: 172 IRGGSDLILIETI 184
>UniRef50_Q9WYA5 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=2; Thermotoga|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Thermotoga maritima
Length = 768
Score = 37.1 bits (82), Expect = 0.22
Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Frame = +3
Query: 108 PDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVR-AVELAKRARSL 284
PD V+ H ++ +G+D+I+TNT+ A+ +H GL ++ + IVR AV +A+RA
Sbjct: 43 PDVVLKVHRSYIESGSDVILTNTFGATRMKLRKH-GL--EDKLDPIVRNAVRIARRAAGE 99
Query: 285 YLEEYQDYVQNDRVPLVVGS 344
L + D +P +GS
Sbjct: 100 KL-VFGDIGPTGELPYPLGS 118
>UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2;
Anaeromyxobacter|Rep: Homocysteine S-methyltransferase -
Anaeromyxobacter sp. Fw109-5
Length = 280
Score = 36.7 bits (81), Expect = 0.29
Identities = 28/88 (31%), Positives = 41/88 (46%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASV 191
+LDGG T L V + + L +L PD + H D AGA++++T T+ +
Sbjct: 13 LLDGGMGTAL---VARGLPQGAL-PEEWLLARPDAIAEVHADHARAGAEIVLTCTFNLAA 68
Query: 192 EGFIEHLGLTRKESYELIVRAVELAKRA 275
+ L R E EL AV LA+ A
Sbjct: 69 PRLAQRLDPPRVE--ELAAIAVRLARGA 94
>UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Victivallis vadensis ATCC BAA-548|Rep:
Methylenetetrahydrofolate reductase - Victivallis
vadensis ATCC BAA-548
Length = 595
Score = 36.7 bits (81), Expect = 0.29
Identities = 24/59 (40%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRA-VELAKRA 275
T PD +++ H +L AGA+++ TNTY A+ + GL+ E E I RA V+LA+ A
Sbjct: 30 TAPDVILDIHHQYLKAGAEVLTTNTYNANSRR-LAKFGLS--EQTEAINRAGVKLAREA 85
>UniRef50_Q1NSQ8 Cluster: Methylenetetrahydrofolate reductase; n=2;
delta proteobacterium MLMS-1|Rep:
Methylenetetrahydrofolate reductase - delta
proteobacterium MLMS-1
Length = 704
Score = 35.9 bits (79), Expect = 0.51
Identities = 38/129 (29%), Positives = 60/129 (46%)
Frame = +3
Query: 108 PDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLY 287
PD + + H +++ AG+ LI TNT+ A+ + + GL ++ E+ + +AKRA
Sbjct: 118 PDLIYSLHEEYIRAGSQLIETNTFGANRLKLLAN-GL-ENQAREINLAGAGIAKRAAG-- 173
Query: 288 LEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALVEA 467
+D V GSVGP G + + V + +I AL+EA
Sbjct: 174 ----EDI-------YVAGSVGPTGVEF----PLEAGEIEPAEVAAA---YEEQISALLEA 215
Query: 468 GVDMLALET 494
VD+L LET
Sbjct: 216 EVDLLILET 224
>UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=2; Epsilonproteobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Nitratiruptor sp. (strain SB155-2)
Length = 1148
Score = 35.9 bits (79), Expect = 0.51
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVI----DGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNT 176
+++DG TQL ++ +G + T P + + H + GAD+I TNT
Sbjct: 11 LIIDGAMGTQLQAKANEISADVWEGKEGCNELLNRTAPKVIKSIHEAYAKVGADIIKTNT 70
Query: 177 YQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGP 353
+ S+ ++ Y+L A +L KR L E + Y ++ V S+GP
Sbjct: 71 F-GSMPWVLDE--------YDLASEAYDLTKRGCELVKEVCETYSTPEKPRFVACSLGP 120
>UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Beggiatoa sp. PS|Rep:
5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Beggiatoa sp. PS
Length = 157
Score = 35.5 bits (78), Expect = 0.68
Identities = 21/67 (31%), Positives = 34/67 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T P + H +L AGAD+I TNT+ A+ ++ + YEL V +LA+ A
Sbjct: 58 TQPHIIKEIHTQYLEAGADIIETNTFNATRIAMADY--RMEELVYELNVAGAKLAREAAD 115
Query: 282 LYLEEYQ 302
+++Q
Sbjct: 116 EMAQKHQ 122
>UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4;
Bacteria|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 826
Score = 35.1 bits (77), Expect = 0.90
Identities = 18/57 (31%), Positives = 33/57 (57%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKR 272
TH +E+ H ++ AG+D+I+TNT+ A+ F + + +E + V V+ A+R
Sbjct: 38 THSEEIYKIHRQYIEAGSDIILTNTFGANALKFHDD-SCSLEEIIKAAVSHVKKAER 93
>UniRef50_Q49775 Cluster: Methionine synthase; n=19; Bacteria|Rep:
Methionine synthase - Mycobacterium leprae
Length = 1206
Score = 35.1 bits (77), Expect = 0.90
Identities = 32/131 (24%), Positives = 57/131 (43%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H + AGADL+ TNT+ + + +LG Y++ + +L++R
Sbjct: 57 TRPDVLETIHRRYFEAGADLVETNTFGCN----LSNLG-----DYDIADKIRDLSQRGTV 107
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
+ + D V+GS+GP G L T + +RD + ++
Sbjct: 108 IARRVADELTTPDHKRYVLGSMGP-GTKL--------PTLGHTEYRVVRDAYTESALGML 158
Query: 462 EAGVDMLALET 494
+ G D + +ET
Sbjct: 159 DGGADAVLVET 169
>UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=60;
Bacilli|Rep: Methylenetetrahydrofolate reductase -
Bacillus halodurans
Length = 618
Score = 34.7 bits (76), Expect = 1.2
Identities = 14/29 (48%), Positives = 22/29 (75%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQAS 188
T P+++V H+ ++ AGAD+I TNTY A+
Sbjct: 38 TDPEKIVAAHVAYVEAGADVIQTNTYAAN 66
>UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep:
Msh - Agrobacterium tumefaciens
Length = 316
Score = 34.7 bits (76), Expect = 1.2
Identities = 21/56 (37%), Positives = 29/56 (51%)
Frame = +3
Query: 12 VLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTY 179
+LDGG +L + P WSA L P+ V H F+ AGA++I TN+Y
Sbjct: 7 ILDGGMGRELLRNGAPF--RQPEWSALSLIEAPEFVKMAHDAFVAAGAEVITTNSY 60
>UniRef50_A3J3G3 Cluster: Lycopene cyclase; n=2;
Flavobacteriales|Rep: Lycopene cyclase - Flavobacteria
bacterium BAL38
Length = 392
Score = 34.7 bits (76), Expect = 1.2
Identities = 13/52 (25%), Positives = 28/52 (53%)
Frame = +3
Query: 84 SARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYE 239
+ RF++ P L++ + DL++ Y+ ++ +I++LG+T E E
Sbjct: 205 NTRFMYVLPTSSTEALLEYTLFSKDLLLKEEYELEIQKYIQNLGITEYEIIE 256
>UniRef50_Q4AEC2 Cluster: Chalcone synthase; n=48;
Spermatophyta|Rep: Chalcone synthase - Triticum aestivum
(Wheat)
Length = 144
Score = 33.9 bits (74), Expect = 2.1
Identities = 23/73 (31%), Positives = 36/73 (49%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
T V G TQL VGQ + GD +A + PD +V L L++ + I+ +T
Sbjct: 71 TAVTFRGPCDTQLDSMVGQALFGDGA-AAVVVGADPDVLVERPLFQLVSASQTILPDT-D 128
Query: 183 ASVEGFIEHLGLT 221
++G + +GLT
Sbjct: 129 GFIKGHLREVGLT 141
>UniRef50_Q8R927 Cluster: Methionine synthase I, cobalamin-binding
domain; n=14; Clostridia|Rep: Methionine synthase I,
cobalamin-binding domain - Thermoanaerobacter
tengcongensis
Length = 803
Score = 33.5 bits (73), Expect = 2.7
Identities = 19/56 (33%), Positives = 35/56 (62%)
Frame = +3
Query: 108 PDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRA 275
P+ V + H ++ AGA++I TNT+ A+ ++ GL K E++ + VE+A++A
Sbjct: 42 PEVVFDIHKAYIEAGAEVIETNTFGANRIKLAKY-GLEDKVE-EIVTKGVEIARKA 95
>UniRef50_Q1GGL5 Cluster: Homocysteine S-methyltransferase; n=30;
Bacteria|Rep: Homocysteine S-methyltransferase -
Silicibacter sp. (strain TM1040)
Length = 340
Score = 33.5 bits (73), Expect = 2.7
Identities = 46/163 (28%), Positives = 70/163 (42%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
++ DG T L Q D LW+ PD++ + + AG+DL +TN++ +
Sbjct: 15 LLADGATGTNLFNMGLQSGDAPELWNT----DAPDKIKALYQGSVDAGSDLFLTNSFGGT 70
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAHL 368
R + ++ R EL + A L E D + +R V GSVGP G +
Sbjct: 71 A---------ARLKLHDAQGRVRELNRIAAELG-REVAD--KAERKIAVAGSVGPTGEIM 118
Query: 369 HDGSEYDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETI 497
E + A + +H + AL E GVD+L LETI
Sbjct: 119 QPVGELSHALA-------VEMFHE-QADALKEGGVDVLWLETI 153
>UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 504
Score = 33.5 bits (73), Expect = 2.7
Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 14/83 (16%)
Frame = +3
Query: 111 DEVVNTHLDFLIAGADLIITNTYQA---------SVEGFIEHLGLTRKESYELIVRAVEL 263
+ + N HL +L++G+++I TNTYQ S+E E + +YE + ++
Sbjct: 41 ENLKNIHLSYLLSGSNIITTNTYQVNLHFKRNNISIENGKEIIDTYIDIAYESCEKYKQI 100
Query: 264 AKRARSLY--LEEYQ---DYVQN 317
KR LY LE Y+ DYV +
Sbjct: 101 KKRNTCLYSDLETYKSPYDYVNH 123
>UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransferase
1; n=61; Eumetazoa|Rep: Betaine--homocysteine
S-methyltransferase 1 - Homo sapiens (Human)
Length = 406
Score = 33.5 bits (73), Expect = 2.7
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DGGF L G V G W+ HP+ V H +FL AG++++ T T+ AS
Sbjct: 23 VIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79
Query: 189 VEGFIEHLG 215
E +E+ G
Sbjct: 80 -EDKLENRG 87
>UniRef50_Q1WUH1 Cluster: TRNA delta(2)-isopentenylpyrophosphate
transferase; n=5; Lactobacillales|Rep: TRNA
delta(2)-isopentenylpyrophosphate transferase -
Lactobacillus salivarius subsp. salivarius (strain
UCC118)
Length = 307
Score = 33.1 bits (72), Expect = 3.6
Identities = 13/48 (27%), Positives = 24/48 (50%)
Frame = +3
Query: 291 EEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDW 434
++ ++ +D +P++VG G Y L DG G D S++ + W
Sbjct: 83 KDIKEIANDDNIPIIVGGTGFYLQALLDGYSLGGDTFDQLSIERRKKW 130
>UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 581
Score = 33.1 bits (72), Expect = 3.6
Identities = 18/57 (31%), Positives = 33/57 (57%)
Frame = +3
Query: 123 NTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLE 293
N HL +L+ G ++I TNT+Q ++ F + LG+ E E++ + + +A + Y E
Sbjct: 47 NIHLSYLLGGCNIIGTNTFQVNLYSF-KKLGIDNGE--EILNKYINIAYNSLLKYEE 100
>UniRef50_Q6MCZ9 Cluster: Putative uncharacterized protein; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Putative uncharacterized protein - Protochlamydia
amoebophila (strain UWE25)
Length = 316
Score = 32.7 bits (71), Expect = 4.8
Identities = 16/53 (30%), Positives = 26/53 (49%)
Frame = +3
Query: 72 DPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKE 230
+P W + +H P E + HLD + I T+Q + EG E + + R+E
Sbjct: 241 EPRWIMQSIHLSPAEALQAHLDLNAKQSLAIHFGTFQLTDEGIKEPVKILRQE 293
>UniRef50_Q67LG1 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=2; Firmicutes|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Symbiobacterium thermophilum
Length = 859
Score = 32.7 bits (71), Expect = 4.8
Identities = 46/166 (27%), Positives = 72/166 (43%), Gaps = 3/166 (1%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDP-LWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQA 185
+V DG T L G P +W+ P++V+ H ++ AGA ++ TNT+
Sbjct: 12 LVFDGAMGTMLQAQ-GLAPGACPDVWNLE----RPEDVIAVHRAYVEAGAQILETNTF-G 65
Query: 186 SVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGAH 365
S + H GL + +++V V A+ A + R V GS+GP GA
Sbjct: 66 STPIRLGHYGL-QDRCRDIVVAGVRCAREAAA------------GRA-WVAGSMGPLGAL 111
Query: 366 LHDGSE--YDGSYADTTSVQTMRDWHRPRIQALVEAGVDMLALETI 497
+ E +D +YA +VQ +A EA D + +ETI
Sbjct: 112 VEPLGELPFDEAYAQ-FAVQA---------RAFAEAQPDFIIIETI 147
>UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine
methyltransferase; n=9; cellular organisms|Rep:
5-Methyltetrahydrofolate-S-homocysteine
methyltransferase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 1168
Score = 32.7 bits (71), Expect = 4.8
Identities = 25/84 (29%), Positives = 40/84 (47%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
+ P+ V H + AGAD++ TNT+ S+ E GL + + E+ A LA+ A
Sbjct: 50 SRPELVREIHRGYFEAGADMVETNTFGGSIVTLAE-FGL-QDRTREINRTAATLAREAAE 107
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGP 353
+ + Y V+GS+GP
Sbjct: 108 TFADGRHRY--------VMGSIGP 123
>UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2;
Desulfitobacterium hafniense|Rep: Homocysteine
S-methyltransferase - Desulfitobacterium hafniense
(strain DCB-2)
Length = 285
Score = 32.7 bits (71), Expect = 4.8
Identities = 24/89 (26%), Positives = 44/89 (49%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DG T L + + G P T P+ + H ++ AG+++I TNT+ A
Sbjct: 9 VIFDGAMGTMLQKY--DLAPGQPPEVLNI--TRPEVIEEVHRKYIKAGSNIITTNTFGA- 63
Query: 189 VEGFIEHLGLTRKESYELIVRAVELAKRA 275
+E + G + + E++ A+ +A+RA
Sbjct: 64 IETKLNGTGYSVE---EVVQSAIAIARRA 89
>UniRef50_A3GFY2 Cluster: Saccharolysin; n=7; Saccharomycetales|Rep:
Saccharolysin - Pichia stipitis (Yeast)
Length = 687
Score = 32.7 bits (71), Expect = 4.8
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 6/97 (6%)
Frame = +3
Query: 204 EHLGLTRKESYELIVRAVE-LAKRARSLYLEEYQ--DYVQNDRVPLVVGSVGPYGAHLHD 374
+ + L KESY L VE L + A L EE + DY+ P + V PY +LH
Sbjct: 4 DFIALASKESYPLWNHTVEDLERLANQLVNEEKETYDYIATIENPTIENVVKPYARYLHK 63
Query: 375 GSEYDGS---YADTTSVQTMRDWHRPRIQALVEAGVD 476
+ + Y ++ + +RD + L +A ++
Sbjct: 64 NALLENQITFYQYVSASKDLRDASTRAEEQLEQASIE 100
>UniRef50_Q1ET86 Cluster: Hydrolase, predicted metal dependent
phosphohydrolase; n=1; Clostridium oremlandii
OhILAs|Rep: Hydrolase, predicted metal dependent
phosphohydrolase - Clostridium oremlandii OhILAs
Length = 218
Score = 32.3 bits (70), Expect = 6.3
Identities = 22/50 (44%), Positives = 27/50 (54%)
Frame = +3
Query: 111 DEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVE 260
DE +N L L +L I N YQ VE E GLT +E+ ELI+ VE
Sbjct: 91 DEKLNKKLKEL-DNKELEINNLYQKEVEKLEELSGLTSEEARELILSDVE 139
>UniRef50_A4Z1H6 Cluster: Putative uncharacterized protein; n=1;
Bradyrhizobium sp. ORS278|Rep: Putative uncharacterized
protein - Bradyrhizobium sp. (strain ORS278)
Length = 510
Score = 32.3 bits (70), Expect = 6.3
Identities = 24/83 (28%), Positives = 40/83 (48%)
Frame = +3
Query: 183 ASVEGFIEHLGLTRKESYELIVRAVELAKRARSLYLEEYQDYVQNDRVPLVVGSVGPYGA 362
AS E + G+ +S ++ + A+R R +E+++ V+ D V LV GP+
Sbjct: 419 ASYEDYARESGMFSSQSLTIVD---DYAQRERRWMIEDFRR-VRPDIV-LVDNMTGPWRK 473
Query: 363 HLHDGSEYDGSYADTTSVQTMRD 431
LH+ E D D +T+RD
Sbjct: 474 WLHESPELDALLMDYRLTETIRD 496
>UniRef50_Q4YA86 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 71
Score = 32.3 bits (70), Expect = 6.3
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = +3
Query: 336 VGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPR 446
VG + + H H G+++ GSY+ T + WH PR
Sbjct: 32 VGGIASW--HNHSGNKFGGSYSTTRGLSYTTPWHLPR 66
>UniRef50_Q22HI1 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Homocysteine S-methyltransferase family protein -
Tetrahymena thermophila SB210
Length = 600
Score = 31.9 bits (69), Expect = 8.3
Identities = 23/95 (24%), Positives = 47/95 (49%)
Frame = +3
Query: 3 TRVVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQ 182
T++ DG + L + + W R L P+++ + HL++ GAD+I + T++
Sbjct: 4 TKIFKDGAVGSLLQQKYPEFYE-QRTWMNRILKEKPEKLYDLHLEYCKQGADIITSFTFK 62
Query: 183 ASVEGFIEHLGLTRKESYELIVRAVELAKRARSLY 287
+ I L +ES +L+ AV+ ++ + +Y
Sbjct: 63 TNP---IACQSL--EESKKLVQIAVKECQKLKEIY 92
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 514,269,262
Number of Sequences: 1657284
Number of extensions: 9775835
Number of successful extensions: 27434
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 26633
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27343
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 29691847201
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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