Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0004_M19
(501 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U75743-1|AAB58906.1| 1265|Homo sapiens methionine synthase protein. 45 1e-04
U73338-1|AAB39704.1| 1265|Homo sapiens methionine synthase protein. 45 1e-04
U71285-1|AAC51188.1| 1265|Homo sapiens 5-methyltetrahydrofolate-... 45 1e-04
BC130616-1|AAI30617.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 45 1e-04
AL359259-1|CAH70983.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 45 1e-04
AL359185-1|CAH73198.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 45 1e-04
BC020665-1|AAH20665.1| 363|Homo sapiens betaine-homocysteine me... 37 0.034
AF257473-1|AAG41356.1| 363|Homo sapiens betaine-homocysteine me... 37 0.034
U50929-1|AAC50668.1| 406|Homo sapiens betaine:homocysteine meth... 33 0.42
M96264-1|AAA74450.1| 379|Homo sapiens galactose-1-phosphate uri... 33 0.42
M60091-1|AAC83409.1| 379|Homo sapiens galactose-1-phosphate uri... 33 0.42
BT009852-1|AAP88854.1| 379|Homo sapiens galactose-1-phosphate u... 33 0.42
BC015045-1|AAH15045.1| 379|Homo sapiens galactose-1-phosphate u... 33 0.42
BC012616-1|AAH12616.1| 406|Homo sapiens betaine-homocysteine me... 33 0.42
AL162231-1|CAH69856.1| 379|Homo sapiens galactose-1-phosphate u... 33 0.42
AF118378-1|AAD22043.1| 406|Homo sapiens betaine-homocysteine me... 33 0.42
>U75743-1|AAB58906.1| 1265|Homo sapiens methionine synthase protein.
Length = 1265
Score = 45.2 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>U73338-1|AAB39704.1| 1265|Homo sapiens methionine synthase protein.
Length = 1265
Score = 45.2 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>U71285-1|AAC51188.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 45.2 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>BC130616-1|AAI30617.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 45.2 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>AL359259-1|CAH70983.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 45.2 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>AL359185-1|CAH73198.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 45.2 bits (102), Expect = 1e-04
Identities = 34/132 (25%), Positives = 66/132 (50%)
Frame = +3
Query: 102 THPDEVVNTHLDFLIAGADLIITNTYQASVEGFIEHLGLTRKESYELIVRAVELAKRARS 281
T PD + H ++L+AGAD+I TNT+ ++ ++ GL +Y + + + +A++A
Sbjct: 73 TQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADY-GLEHL-AYRMNMCSAGVARKA-- 128
Query: 282 LYLEEYQDYVQNDRVPLVVGSVGPYGAHLHDGSEYDGSYADTTSVQTMRDWHRPRIQALV 461
EE +Q V G++GP L + + + + ++ + + L+
Sbjct: 129 --AEEVT--LQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLL 184
Query: 462 EAGVDMLALETI 497
+ GVD+L +ETI
Sbjct: 185 DGGVDILLIETI 196
>BC020665-1|AAH20665.1| 363|Homo sapiens betaine-homocysteine
methyltransferase 2 protein.
Length = 363
Score = 37.1 bits (82), Expect = 0.034
Identities = 23/60 (38%), Positives = 33/60 (55%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DG F L G V G LW+ + HPD V H++FL AG++++ T T+ AS
Sbjct: 23 VIGDGSFLITLEKR-GYVKAG--LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQTFTFSAS 79
>AF257473-1|AAG41356.1| 363|Homo sapiens betaine-homocysteine
methyltransferase 2 protein.
Length = 363
Score = 37.1 bits (82), Expect = 0.034
Identities = 23/60 (38%), Positives = 33/60 (55%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DG F L G V G LW+ + HPD V H++FL AG++++ T T+ AS
Sbjct: 23 VIGDGSFLITLEKR-GYVKAG--LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQTFTFSAS 79
>U50929-1|AAC50668.1| 406|Homo sapiens betaine:homocysteine
methyltransferase protein.
Length = 406
Score = 33.5 bits (73), Expect = 0.42
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DGGF L G V G W+ HP+ V H +FL AG++++ T T+ AS
Sbjct: 23 VIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79
Query: 189 VEGFIEHLG 215
E +E+ G
Sbjct: 80 -EDKLENRG 87
>M96264-1|AAA74450.1| 379|Homo sapiens galactose-1-phosphate uridyl
transferase protein.
Length = 379
Score = 33.5 bits (73), Expect = 0.42
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 265 PNEHALYT*KNIRTTCKTIAFH*WSD 342
P++H L+ K+ R CK + FH WSD
Sbjct: 111 PSDHPLFQAKSARGVCKVMCFHPWSD 136
>M60091-1|AAC83409.1| 379|Homo sapiens galactose-1-phosphate uridyl
transferase protein.
Length = 379
Score = 33.5 bits (73), Expect = 0.42
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 265 PNEHALYT*KNIRTTCKTIAFH*WSD 342
P++H L+ K+ R CK + FH WSD
Sbjct: 111 PSDHPLFQAKSARGVCKVMCFHPWSD 136
>BT009852-1|AAP88854.1| 379|Homo sapiens galactose-1-phosphate
uridylyltransferase protein.
Length = 379
Score = 33.5 bits (73), Expect = 0.42
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 265 PNEHALYT*KNIRTTCKTIAFH*WSD 342
P++H L+ K+ R CK + FH WSD
Sbjct: 111 PSDHPLFQAKSARGVCKVMCFHPWSD 136
>BC015045-1|AAH15045.1| 379|Homo sapiens galactose-1-phosphate
uridylyltransferase protein.
Length = 379
Score = 33.5 bits (73), Expect = 0.42
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 265 PNEHALYT*KNIRTTCKTIAFH*WSD 342
P++H L+ K+ R CK + FH WSD
Sbjct: 111 PSDHPLFQAKSARGVCKVMCFHPWSD 136
>BC012616-1|AAH12616.1| 406|Homo sapiens betaine-homocysteine
methyltransferase protein.
Length = 406
Score = 33.5 bits (73), Expect = 0.42
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DGGF L G V G W+ HP+ V H +FL AG++++ T T+ AS
Sbjct: 23 VIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79
Query: 189 VEGFIEHLG 215
E +E+ G
Sbjct: 80 -EDKLENRG 87
>AL162231-1|CAH69856.1| 379|Homo sapiens galactose-1-phosphate
uridylyltransferase protein.
Length = 379
Score = 33.5 bits (73), Expect = 0.42
Identities = 12/26 (46%), Positives = 17/26 (65%)
Frame = +1
Query: 265 PNEHALYT*KNIRTTCKTIAFH*WSD 342
P++H L+ K+ R CK + FH WSD
Sbjct: 111 PSDHPLFQAKSARGVCKVMCFHPWSD 136
>AF118378-1|AAD22043.1| 406|Homo sapiens betaine-homocysteine
methyltransferase protein.
Length = 406
Score = 33.5 bits (73), Expect = 0.42
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +3
Query: 9 VVLDGGFSTQLSCHVGQVIDGDPLWSARFLHTHPDEVVNTHLDFLIAGADLIITNTYQAS 188
V+ DGGF L G V G W+ HP+ V H +FL AG++++ T T+ AS
Sbjct: 23 VIGDGGFVFALEKR-GYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYAS 79
Query: 189 VEGFIEHLG 215
E +E+ G
Sbjct: 80 -EDKLENRG 87
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,397,227
Number of Sequences: 237096
Number of extensions: 1452531
Number of successful extensions: 3457
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3337
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3451
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4593178062
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -