Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0004_D19
(627 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 182 5e-45
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 153 2e-36
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 148 1e-34
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 118 1e-25
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 100 3e-20
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 93 4e-18
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 92 9e-18
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 91 2e-17
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 91 3e-17
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 89 6e-17
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 89 1e-16
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 88 2e-16
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 87 4e-16
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 86 6e-16
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 83 5e-15
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 83 7e-15
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 82 9e-15
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 80 4e-14
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 80 4e-14
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 80 5e-14
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 79 7e-14
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 78 2e-13
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 78 2e-13
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 74 2e-12
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 74 3e-12
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 74 3e-12
UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3; Proteobacter... 73 4e-12
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 73 6e-12
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 72 1e-11
UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7; ... 70 4e-11
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 69 7e-11
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 69 9e-11
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 69 1e-10
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 69 1e-10
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 67 4e-10
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 67 4e-10
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 66 5e-10
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 66 6e-10
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 66 9e-10
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 66 9e-10
UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratu... 66 9e-10
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 65 1e-09
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 65 1e-09
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 65 1e-09
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 64 2e-09
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 64 2e-09
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 64 3e-09
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 61 2e-08
UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;... 60 3e-08
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 58 1e-07
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 58 2e-07
UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.... 58 2e-07
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 58 2e-07
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 57 4e-07
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 56 7e-07
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 56 9e-07
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 55 1e-06
UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4; Bact... 55 1e-06
UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid sy... 55 2e-06
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 55 2e-06
UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;... 54 2e-06
UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Re... 52 1e-05
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 51 2e-05
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 50 5e-05
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 50 6e-05
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 49 8e-05
UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;... 49 1e-04
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 48 1e-04
UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid ... 47 4e-04
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 47 4e-04
UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6; Helicobacter... 46 6e-04
UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep... 43 0.005
UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio... 42 0.012
UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;... 42 0.012
UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis ... 41 0.028
UniRef50_Q88Z00 Cluster: Non-ribosomal peptide synthetase NpsB; ... 39 0.11
UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1... 38 0.20
UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis related-pro... 38 0.26
UniRef50_A2ENS5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.34
UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;... 37 0.34
UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus... 36 0.60
UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix o... 36 0.79
UniRef50_UPI0000E117D8 Cluster: Na(+)-translocating NADH-quinone... 35 1.4
UniRef50_UPI000038CA6C Cluster: COG5295: Autotransporter adhesin... 34 3.2
UniRef50_A5AVR4 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_Q54Y66 Cluster: Small GTPase; n=2; Dictyostelium discoi... 33 5.6
UniRef50_UPI0000499648 Cluster: hypothetical protein 263.t00006;... 33 7.4
UniRef50_Q54LZ9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_Q7MVQ9 Cluster: Putative uncharacterized protein; n=1; ... 32 9.8
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 182 bits (444), Expect = 5e-45
Identities = 82/145 (56%), Positives = 108/145 (74%)
Frame = +1
Query: 190 LEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKF 369
LE+++ VGG +PCFIIAE+G NHQGD+ +AK++I+ AK+ GA C KFQK+ L+ KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 370 TKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFL 549
+K LER Y + +SWGKTYG+HK+HLEFS QYREL +YA E+GI FTAS MD ++ +FL
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFL 122
Query: 550 VNLKVPFIKIGSGDSNKLLVLKYAA 624
L VPF K+GSGD+N L+ A
Sbjct: 123 HELNVPFFKVGSGDTNNFPYLEKTA 147
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 153 bits (372), Expect = 2e-36
Identities = 67/113 (59%), Positives = 88/113 (77%)
Frame = +1
Query: 190 LEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKF 369
LE+++ VGG +PCFIIAE+G NHQGD+ +AK++I+ AK+ GA C KFQK+ L+ KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 370 TKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMD 528
+K LER Y + +SWGKTYG+HK+HLEF+ QYREL +YA E+GI FTAS MD
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVGIFFTASGMD 115
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 148 bits (358), Expect = 1e-34
Identities = 71/129 (55%), Positives = 94/129 (72%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
+IIAE+G NHQG + AK++I AK AG CVKFQK+ L KFT+ L+R Y + ++WGK
Sbjct: 16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGK 75
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNK 600
TYG+HK++LEFS+ QY +L + E+ + FTASAMD S +FL L VPFIKIGSGD+N
Sbjct: 76 TYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANN 135
Query: 601 LLVLKYAAS 627
+LK AA+
Sbjct: 136 FPLLKKAAN 144
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 118 bits (284), Expect = 1e-25
Identities = 61/136 (44%), Positives = 82/136 (60%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
V NP F+IAEVG NHQGDI K + KAAK+AGA VK QK + FT + + YD
Sbjct: 12 VTDENPSFVIAEVGHNHQGDIEKCKAIFKAAKEAGADAVKIQKRDNRALFTAEMYDSHYD 71
Query: 400 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
+ N++ TYG H++ LEF+ QY EL +Y ++ ILF ++A D S + L + +P KI
Sbjct: 72 SENAYAHTYGTHRECLEFNREQYLELKEYCKQLDILFFSTAFDEPSAELLEEIDMPGFKI 131
Query: 580 GSGDSNKLLVLKYAAS 627
SGD +LK AS
Sbjct: 132 ASGDLVNTPLLKKVAS 147
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 100 bits (239), Expect = 3e-20
Identities = 51/122 (41%), Positives = 71/122 (58%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
VG + PC++IAE+G NH GD+ IAK+LI A AG VKFQK + +T L +
Sbjct: 20 VGKDQPCYVIAEIGINHNGDMDIAKRLISVAVGAGCDAVKFQKRTIDVVYTAAELAK--P 77
Query: 400 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
N +G T GD K+ LEF +++E+ +Y E+ + + ASA D S DF+ VP KI
Sbjct: 78 RENPFGATNGDLKRGLEFGLEEFKEIDRYCREVRMPWFASAWDEASVDFIAQFDVPCFKI 137
Query: 580 GS 585
S
Sbjct: 138 AS 139
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 93.5 bits (222), Expect = 4e-18
Identities = 48/115 (41%), Positives = 69/115 (60%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
F+IAE+G NH GD+ I KQLI+AA+DAG VKFQK + +T + L + + WG
Sbjct: 34 FVIAEIGINHNGDLEITKQLIRAARDAGCDAVKFQKRTIDIVYTPEVL--AQPRQSPWGD 91
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 585
T K+ LEF +++Y + Y E+G+ + ASA D+ S FL +P+ KI S
Sbjct: 92 TQRAQKEGLEFGKAEYDVIDAYCRELGLAWFASAWDVPSQTFLAAYDLPYNKIAS 146
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 92.3 bits (219), Expect = 9e-18
Identities = 56/135 (41%), Positives = 73/135 (54%), Gaps = 3/135 (2%)
Frame = +1
Query: 232 NPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERS-YDNHN 408
N +IIAE G NH G + +A QL AAKDAGA VKFQ T EK + E + Y +N
Sbjct: 3 NHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQ-TWKTEKIVTRNAELAVYQENN 61
Query: 409 SWGKTYGDHK--KHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIG 582
KT K K LE S + + + EIGI F ++ ++ S DFL N +PFIK+G
Sbjct: 62 ISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLG 121
Query: 583 SGDSNKLLVLKYAAS 627
SGD + L+ S
Sbjct: 122 SGDVTNIPFLRLVGS 136
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/140 (37%), Positives = 72/140 (51%), Gaps = 2/140 (1%)
Frame = +1
Query: 211 DVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLER 390
+V VG NP ++IAE+G NH GD+ + +QLI AA +AGA VKFQ ++ ER
Sbjct: 8 NVPVGAENPPYVIAEIGSNHNGDMNLCRQLIDAAAEAGAHAVKFQSWTENSLIAREEYER 67
Query: 391 S--YDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKV 564
+ Y + + D K + + Q+RE Y E GI F ++ D L +L V
Sbjct: 68 NTEYSDKKRHFGSLRDMVKTYQLTTDQHREAHAYCRERGIAFCSTPFSPEEADLLESLDV 127
Query: 565 PFIKIGSGDSNKLLVLKYAA 624
PF KI S D L LKY A
Sbjct: 128 PFFKIASMDIVHLPFLKYVA 147
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/132 (40%), Positives = 79/132 (59%), Gaps = 2/132 (1%)
Frame = +1
Query: 238 CFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERS-YDNHNS- 411
CFIIAE G NH GD+ +AK+L+ AAK++GA VKFQ T + K +E++ Y +N+
Sbjct: 3 CFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQ-TFKADTLVNKTVEKAEYQKNNAP 61
Query: 412 WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 591
T + K LE SE + L + A+ +GI F ++ D S DFL++L V +KI SG+
Sbjct: 62 ESSTQYEMLKALELSEEDHYLLSELANSLGIEFMSTGFDEQSIDFLISLGVKRLKIPSGE 121
Query: 592 SNKLLVLKYAAS 627
+ L++ AS
Sbjct: 122 ITNVPYLQHCAS 133
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 89.4 bits (212), Expect = 6e-17
Identities = 49/128 (38%), Positives = 74/128 (57%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
++IAE+G NH GDI A ++I+ +K+AG VKFQK + ++ + L R +N +G
Sbjct: 8 YVIAEIGINHNGDIDQALEMIRKSKEAGCDAVKFQKRTVDVVYSAEELARPREN--VFGT 65
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNK 600
T GD K+ LEF ++ Y + K E+GI + AS D S DFL++ P+IK+ S
Sbjct: 66 TNGDLKRGLEFGKADYDRIDKLCKELGIDWFASPWDEGSVDFLLDYDTPYIKVASAMVTD 125
Query: 601 LLVLKYAA 624
L+Y A
Sbjct: 126 RDFLEYCA 133
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 88.6 bits (210), Expect = 1e-16
Identities = 55/135 (40%), Positives = 74/135 (54%)
Frame = +1
Query: 187 MLEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEK 366
M ++KI D VG P FIIAE G NH GDI I K+L+K AK GA +KFQ ++
Sbjct: 1 MEKIKIG-DRYVGKGEPTFIIAEGGLNHNGDIDIGKELVKEAKKCGADAIKFQSYHTEDF 59
Query: 367 FTKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDF 546
+KK Y + K LE SE ++ EL +YA +IGI+F ++ +D+ D
Sbjct: 60 ISKK-------------SEYYELFKSLELSEEEFYELKEYAEKIGIMFISTPLDLKYVDI 106
Query: 547 LVNLKVPFIKIGSGD 591
L + VP KI SGD
Sbjct: 107 LNKMNVPAFKIASGD 121
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 87.8 bits (208), Expect = 2e-16
Identities = 57/143 (39%), Positives = 81/143 (56%), Gaps = 1/143 (0%)
Frame = +1
Query: 202 ITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKY 381
I ++ VG +P ++AE+G NH D I K+ I AAK AGA VKFQ + + E+F
Sbjct: 9 IASELYVGSESPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQVVKFQ-SYVTEEFI--- 64
Query: 382 LERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLK 561
D HN K D K E SE+ +R+ K A + G+ F ++ + + S L++LK
Sbjct: 65 -----DVHNPDAKILVDIFKKYELSETMHRKFQKTAEDEGLFFFSTPLCVNSLHLLLSLK 119
Query: 562 VPFIKIGSGD-SNKLLVLKYAAS 627
VP IKI SGD +NK L+L+ A S
Sbjct: 120 VPAIKIASGDITNKTLLLETAKS 142
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 86.6 bits (205), Expect = 4e-16
Identities = 46/127 (36%), Positives = 78/127 (61%), Gaps = 2/127 (1%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIK-AAKDAGASCVKFQKTCLKEKFTKKYLERSYD-NHNSWG 417
+IAE+G NH+G++ IA ++IK AA+ VKFQK E T + + HNS+G
Sbjct: 6 VIAEIGCNHKGEMEIAHEMIKVAAQFCKVDIVKFQKRTPVELLTPEEYNAPHPVPHNSYG 65
Query: 418 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 597
KTYG+H++ LEF+ Q+++L K+ + G++++ S D+ + +V++ IKI S +
Sbjct: 66 KTYGEHREFLEFNLDQHKQLKKWCDDWGVVYSTSVWDLTAAKEIVSINPELIKIPSACNL 125
Query: 598 KLLVLKY 618
K +L+Y
Sbjct: 126 KFDMLEY 132
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 86.2 bits (204), Expect = 6e-16
Identities = 52/135 (38%), Positives = 71/135 (52%), Gaps = 2/135 (1%)
Frame = +1
Query: 226 GNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNH 405
G FIIAE G NH G + +AK+LI A +AG VKFQ + T+ + Y
Sbjct: 11 GLKNAFIIAEAGVNHNGSLELAKKLIDVAFEAGVDAVKFQTFKTENVVTENAEKAEYQIQ 70
Query: 406 NSWGKTYGDHK--KHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
N+ ++ ++ K LE SE + L+ Y E GILF ++ D S DFL +L VP KI
Sbjct: 71 NTGVESESQYEMIKKLELSEKDFERLYNYCQEKGILFLSTPFDFESADFLDDL-VPLFKI 129
Query: 580 GSGDSNKLLVLKYAA 624
S D N + LK+ A
Sbjct: 130 SSTDLNNIPFLKHIA 144
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 83.0 bits (196), Expect = 5e-15
Identities = 46/136 (33%), Positives = 69/136 (50%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
++ +P +I+AE+G NH G+I +A +LI +AKDAGA VKFQ E + Y
Sbjct: 11 RISSIDPTYIVAEIGVNHNGNISLAHKLIDSAKDAGADAVKFQTYVTDELVIRNTRTAKY 70
Query: 397 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
N+ + E S + EL+++ GI F ++ D VS F+ NLK IK
Sbjct: 71 QKENALFDDQYTMLEKYELSFESFHELYRHCAAAGIDFLSTPFDPVSLRFIANLKPVAIK 130
Query: 577 IGSGDSNKLLVLKYAA 624
SG+ ++L AA
Sbjct: 131 WASGELTNKMLLDQAA 146
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 82.6 bits (195), Expect = 7e-15
Identities = 44/140 (31%), Positives = 76/140 (54%), Gaps = 7/140 (5%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
K+G N P +I+AE+G NH GD+ +AK++I+ A + G VKFQ +T K L
Sbjct: 11 KIGENYPAYIVAEIGANHNGDVNLAKRMIEVAAECGVDAVKFQ------TYTAKELVSDT 64
Query: 397 DNHNSWG-------KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN 555
D +WG +T G + ++E+F+YA+++G++ ++ + +FL
Sbjct: 65 DRILTWGPCGKQKTETIGKMFDRIALPREAHKEVFEYANKLGLMAFSTPFSIKGVEFLNE 124
Query: 556 LKVPFIKIGSGDSNKLLVLK 615
L+VP K+ + D + L +LK
Sbjct: 125 LEVPCFKVAASDVDYLDILK 144
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 82.2 bits (194), Expect = 9e-15
Identities = 50/134 (37%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Frame = +1
Query: 193 EVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFT 372
++ I +D ++ P +IIAE+G NH G+I AK+LI A DAGA+ VKFQK L + +
Sbjct: 7 DIVIGKD-RISTKEPAYIIAEIGINHNGNITTAKKLIDVAVDAGANAVKFQKRSLNDIYR 65
Query: 373 KKYLERSYDNHNSWG-KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFL 549
+ L+ N S G + D +EF + Y+EL +Y E I F + D+ S +FL
Sbjct: 66 EDVLKD--PNIESQGLEILLDVLNEVEFDDDAYKELTEYCKEKHITFLCTPWDIPSVEFL 123
Query: 550 VNLKVPFIKIGSGD 591
+P KI S D
Sbjct: 124 EKFDLPAYKIASAD 137
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 80.2 bits (189), Expect = 4e-14
Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+G + CF+IAE G NH GD+ +A +LI A AGA +KFQ + + + +Y
Sbjct: 23 IGNDGRCFVIAEAGVNHNGDVAMAHRLIDVAAAAGADAIKFQTFNAETLVDRSARKAAYQ 82
Query: 400 NHNSWGK-TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
N+ + + + + LE YR L +A + GI ++ D S DFL L VP K
Sbjct: 83 VTNTGSESSQFEMLRSLELPAQAYRALQDHAGQAGIALISTPFDEASVDFLATLGVPAYK 142
Query: 577 IGSGDSNKLLVLKYAAS 627
+ SGD +L+ A+
Sbjct: 143 VSSGDLTNHFLLEAVAA 159
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 80.2 bits (189), Expect = 4e-14
Identities = 49/147 (33%), Positives = 75/147 (51%), Gaps = 1/147 (0%)
Frame = +1
Query: 187 MLEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEK 366
M +KI ED + +PCFIIAE G NH G + +A +L++ AK+ G CVKFQ +
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNGKLEMALELVRKAKEIGVDCVKFQTFTAESV 59
Query: 367 FTKKYLERSYD-NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFD 543
TKK + +Y ++ + K LE S Y ++ + ++ I F ++ + D
Sbjct: 60 ITKKAPKANYQLEVTDPAESQFEMLKKLELSGDDYIKIIEECNKQNITFLSTPYNEEDAD 119
Query: 544 FLVNLKVPFIKIGSGDSNKLLVLKYAA 624
FL L V KI SG +L L++ A
Sbjct: 120 FLNKLGVSAFKIASGQIVELAFLEHVA 146
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 79.8 bits (188), Expect = 5e-14
Identities = 47/138 (34%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
K+G P FIIAE+G NH G + +AK+L+ AK AGA CVKFQ + + +
Sbjct: 123 KIGDQEPSFIIAEIGNNHNGSLELAKELVDLAKAAGADCVKFQMRDMASMYNNE--GDDD 180
Query: 397 DNHNSWGKTYG-DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFI 573
D G Y D K + + ++ E+F+Y + IL + D S D L + V
Sbjct: 181 DASQDLGAQYVLDLLKRFQLCDEEFVEIFEYCKQKEILALCTPFDEASADKLEKIGVAGF 240
Query: 574 KIGSGDSNKLLVLKYAAS 627
K+ S D +LKY A+
Sbjct: 241 KVASADLTNHRLLKYLAA 258
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 79.4 bits (187), Expect = 7e-14
Identities = 56/134 (41%), Positives = 69/134 (51%), Gaps = 2/134 (1%)
Frame = +1
Query: 232 NPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQ--KTCLKEKFTKKYLERSYDNH 405
N FIIAE G NH GDI +AKQLI AA DAG VKFQ KT L K E +N
Sbjct: 3 NKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVEN- 61
Query: 406 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 585
+T + K LE S + EL Y + GI F ++ + S FL L+ F KIGS
Sbjct: 62 TQREETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVF-KIGS 120
Query: 586 GDSNKLLVLKYAAS 627
G+ L++ AS
Sbjct: 121 GELTNTPFLRHIAS 134
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 77.8 bits (183), Expect = 2e-13
Identities = 51/129 (39%), Positives = 73/129 (56%), Gaps = 3/129 (2%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN-SWGK 420
IIAE G NH GD +A+ L+ +A AGA VKFQ K T+K + +Y N +
Sbjct: 4 IIAEAGVNHNGDAKLARDLVTSAHKAGADIVKFQTFKAKNIVTEKATQANYQKKNLGREE 63
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGD-S 594
+ + LE S + EL Y +E+GI F ++A D S +FLVN L + +K+ SG+ +
Sbjct: 64 SQLAMLQRLELSHELHYELVDYCNELGIEFLSTAFDDESLNFLVNDLGLKRLKLPSGEIT 123
Query: 595 NKLLVLKYA 621
N LVLK+A
Sbjct: 124 NAPLVLKHA 132
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 77.8 bits (183), Expect = 2e-13
Identities = 50/147 (34%), Positives = 76/147 (51%)
Frame = +1
Query: 187 MLEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEK 366
M ++KI + +G +PCFIIAE G NH GDI AK+L+ A +AGA+ VKFQ +
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 367 FTKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDF 546
F+K NH + K+ EF ++E+ +Y + GI+F + + D
Sbjct: 60 FSK--------NHPA-----NKIVKNFEFKLEWHKEMKEYCDKKGIMFITTPFQKDAVDL 106
Query: 547 LVNLKVPFIKIGSGDSNKLLVLKYAAS 627
L L + KI SGD + +L Y ++
Sbjct: 107 LEKLNIEGYKIASGDMDYYPLLDYISN 133
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 74.1 bits (174), Expect = 2e-12
Identities = 47/132 (35%), Positives = 65/132 (49%), Gaps = 1/132 (0%)
Frame = +1
Query: 232 NPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 411
N F++AE G NH G I A +++AA AGA +KFQ T + +Y N
Sbjct: 13 NWVFVVAEAGVNHNGSIERALDMVEAAARAGADAIKFQTFRAAGLVTANAEKAAYQKRND 72
Query: 412 WGKT-YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 588
T + LE SESQ+R + + +GI F ++ D S DFL +L V KI SG
Sbjct: 73 GIDTNQAEMLSALELSESQWRTIKDHCSMVGISFLSTPFDEDSADFLESLGVEAFKISSG 132
Query: 589 DSNKLLVLKYAA 624
D L L++ A
Sbjct: 133 DLTHLAFLQHVA 144
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 73.7 bits (173), Expect = 3e-12
Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 2/138 (1%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+G +PCF+IAE+G NH GDI A QLI AA AGA C KFQ + + ++ +S D
Sbjct: 128 IGAEHPCFVIAEIGNNHNGDINTALQLIDAAHAAGADCAKFQMRDMGQLYSNS--GKSSD 185
Query: 400 NHNSWGKTYG-DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
+ G Y D + + S+ + F Y+ G++ + D S L + K
Sbjct: 186 MASDLGTQYTLDLLERFQLSDDELFHCFDYSASKGLVPLCTPWDQTSLQKLNQWGMEGFK 245
Query: 577 IGSGD-SNKLLVLKYAAS 627
+ S D +N L+ + AA+
Sbjct: 246 VASADFTNHALITQLAAT 263
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 73.7 bits (173), Expect = 3e-12
Identities = 45/131 (34%), Positives = 72/131 (54%), Gaps = 3/131 (2%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQ---KTCLKEKFTKKYLERSYDNHNS 411
++IAE+G NH+G I IAK+LI AKD GA KFQ L K + Y +R+ + S
Sbjct: 29 YVIAEIGVNHEGSIDIAKRLIDEAKDGGADGAKFQTYKAETLASKNSPSYWDRTQEPTAS 88
Query: 412 WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 591
+ + KK+ F +Y L K+ +GI F ++ D+ + + L + ++PFIK+ S D
Sbjct: 89 QFELF---KKYDSFGWKEYEILAKHCQSVGIDFLSTPFDLEAVEHLAS-QMPFIKVASAD 144
Query: 592 SNKLLVLKYAA 624
+ +L+ A
Sbjct: 145 ITSVPLLRSVA 155
>UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3;
Proteobacteria|Rep: Sialic acid synthase - Vibrio
vulnificus (strain YJ016)
Length = 357
Score = 73.3 bits (172), Expect = 4e-12
Identities = 49/129 (37%), Positives = 72/129 (55%), Gaps = 3/129 (2%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSW-GK 420
IIAE G NH GD +A +L+ AA AGA VKFQ K T++ + Y N+ +
Sbjct: 4 IIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQE 63
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGD-S 594
+ LE S + + +L K+ +GI F ++A D S DFLVN L + +K+ SG+ +
Sbjct: 64 SQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELT 123
Query: 595 NKLLVLKYA 621
N LVL++A
Sbjct: 124 NAPLVLEHA 132
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 72.9 bits (171), Expect = 6e-12
Identities = 38/136 (27%), Positives = 76/136 (55%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
K+G +P +IAE+G NH GD+ +AK++++ A +G VK Q + ++ T++ +
Sbjct: 7 KIGPEHPPLVIAEIGINHGGDLAVAKEMVRLAALSGCEMVKHQTHIIADEMTEEARQIFP 66
Query: 397 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
N + + + + S + EL +Y +G+++ ++ + DFL +L VP K
Sbjct: 67 PNAD---VSIWEVMEACALSLDEEAELKRYTESLGMIWISTPFSRAAADFLQDLDVPAFK 123
Query: 577 IGSGDSNKLLVLKYAA 624
IGSG+++ L ++++ A
Sbjct: 124 IGSGEADNLPLIRHIA 139
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 72.1 bits (169), Expect = 1e-11
Identities = 46/138 (33%), Positives = 74/138 (53%)
Frame = +1
Query: 211 DVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLER 390
++K+GGNNP FIIAE G NH GD+ +A ++I A DA A+ +KFQ +E+F +
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGE----- 63
Query: 391 SYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPF 570
K + K EF + ++ L + + + ILF A+ D+ + + L + V
Sbjct: 64 --------NKEAVNLVKPAEFGKKEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEI 115
Query: 571 IKIGSGDSNKLLVLKYAA 624
+KI S D + +L+ AA
Sbjct: 116 LKIASCDICNITLLEAAA 133
>UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7;
Proteobacteria|Rep: N-acetylneuraminic acid synthase -
Chromobacterium violaceum
Length = 361
Score = 70.1 bits (164), Expect = 4e-11
Identities = 47/133 (35%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = +1
Query: 232 NPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 411
N FIIAE G NH G + +A +LI AAK+AGA VKFQ + + Y +
Sbjct: 2 NHVFIIAEAGVNHNGSLKVALELIDAAKEAGADAVKFQTFKSGAVISMDAPKAEYQKTTT 61
Query: 412 -WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLV-NLKVPFIKIGS 585
++ D + LE S + +L ++ + GILF ++ D+ S + LV L VP +K+ S
Sbjct: 62 GTSESQLDMVRKLELSAEDHIQLLQHCEKRGILFLSTPFDVQSAELLVRELGVPQLKVPS 121
Query: 586 GD-SNKLLVLKYA 621
G+ +N +LK A
Sbjct: 122 GELTNAPFLLKIA 134
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 69.3 bits (162), Expect = 7e-11
Identities = 44/130 (33%), Positives = 68/130 (52%), Gaps = 2/130 (1%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG- 417
+I+AE+G NH GD +AK+++K AK AG VKFQ T E+ KY ++ G
Sbjct: 9 YIVAEIGCNHNGDFELAKKMVKEAKSAGVDAVKFQ-TFKAEQLISKYAPKAEYQIKVTGN 67
Query: 418 -KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 594
+T + + LE ++ +L +YA E+G+ ++ D S DFL + KI SG+
Sbjct: 68 EETQLEMTRKLELPYDEFIKLEEYAKELGLDVFSTPFDFDSIDFLASRNQKVWKIPSGEL 127
Query: 595 NKLLVLKYAA 624
L L+ A
Sbjct: 128 LNLPYLEKIA 137
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 68.9 bits (161), Expect = 9e-11
Identities = 47/128 (36%), Positives = 64/128 (50%), Gaps = 1/128 (0%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS-WGK 420
IIAE G NH G + A L+ AA DAGA VKFQ K + Y + +
Sbjct: 7 IIAEAGVNHDGSLEKALALVDAAADAGADIVKFQTFNAKALAGGAAKKADYQQRTTDAAE 66
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNK 600
+ + LE ++ + L + A E GI F ++ D S FL++LK+P IKIGSGD
Sbjct: 67 SQLAMLERLELPQAAHHTLIERAAERGIEFLSTPFDDASLGFLLSLKLPRIKIGSGDLTN 126
Query: 601 LLVLKYAA 624
+L AA
Sbjct: 127 APLLHAAA 134
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 1/126 (0%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN-SWG 417
++IAE+G NH G + +A + I AK+ GA+ VKFQ + +KK Y N
Sbjct: 7 YVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKTNKLVSKKAPMAKYQKDNLKED 66
Query: 418 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 597
+ + K LE S+S + + Y + I F ++ D S DFL + V KIGSGD
Sbjct: 67 SSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFDEESADFLKQIGVQGFKIGSGDLT 126
Query: 598 KLLVLK 615
L L+
Sbjct: 127 NLPFLR 132
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/127 (33%), Positives = 63/127 (49%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 423
IIAE G NH G+I A +LI +AK AGA +KFQ E + + Y + T
Sbjct: 5 IIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRST 64
Query: 424 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNKL 603
+ LE +E +++ + Y +I I F ++A D L+ LKV IK+ SG+
Sbjct: 65 QREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHW 124
Query: 604 LVLKYAA 624
+LK A
Sbjct: 125 PLLKEMA 131
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 66.9 bits (156), Expect = 4e-10
Identities = 49/131 (37%), Positives = 65/131 (49%)
Frame = +1
Query: 232 NPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 411
NP IAE+G +H G I A+ LI A +AGA VKFQ E + Y + +
Sbjct: 19 NP-LTIAEIGTSHNGSIQKARNLIDVAAEAGAKAVKFQIVYADEIL---HPNTGYVDLPT 74
Query: 412 WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 591
D K LE S Y+EL +Y+ +LF+AS S + L LK FIKI S +
Sbjct: 75 GKIPLYDRFKSLELPVSFYKELAEYSRSKKLLFSASPFGFRSAEELAALKPDFIKIASPE 134
Query: 592 SNKLLVLKYAA 624
N + +LKY A
Sbjct: 135 LNYVQLLKYCA 145
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 66.9 bits (156), Expect = 4e-10
Identities = 46/137 (33%), Positives = 66/137 (48%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
KVG + FIIAE+G NH G+I +A +LI A AGA VKFQ + +K Y
Sbjct: 10 KVGEKSSIFIIAEIGVNHNGNIDLAYKLIDLASKAGADAVKFQMF-----YPEKLCSEIY 64
Query: 397 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
K + K S ++L Y + +G+ F + D S D ++NL IK
Sbjct: 65 ------RKDEIEMLKKYVLSFENMKKLRDYTYSLGLEFIVTPFDFKSLDDIINLDCSAIK 118
Query: 577 IGSGDSNKLLVLKYAAS 627
+ SG+ + +K AAS
Sbjct: 119 VASGELTHIPFIKKAAS 135
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 66.5 bits (155), Expect = 5e-10
Identities = 41/139 (29%), Positives = 67/139 (48%), Gaps = 11/139 (7%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAA-----KDAGA------SCVKFQKTCLKEKFTKKYLE 387
+II E+G NH G + +AK +I+ +D + VK K L E+ +
Sbjct: 5 YIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMN 64
Query: 388 RSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVP 567
+ YDN NS+G+TYG+H+ LE + + E++KYA +G+ F + L
Sbjct: 65 QIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPD 124
Query: 568 FIKIGSGDSNKLLVLKYAA 624
+K+ S D L +L+ A
Sbjct: 125 RLKVASRDLTNLPLLEALA 143
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 66.1 bits (154), Expect = 6e-10
Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
F+IAE G NH G + A +L+ A +AGA VKFQ E T + +Y +
Sbjct: 12 FVIAEAGVNHDGSLDKALRLVDIAVEAGADAVKFQTFRTDEVVTPDAAKAAYQQRQTGAG 71
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD-SN 597
T + + LE ++ + L ++ E GI F ++ + D L+ L + IKI SG+ N
Sbjct: 72 TQYEMIRALELDDAAHERLARHCAERGIEFMSTPFAPWAVDMLLGLGMRRIKIASGEIVN 131
Query: 598 KLLVLKYAAS 627
K L+ K A S
Sbjct: 132 KPLIDKVAGS 141
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 65.7 bits (153), Expect = 9e-10
Identities = 38/119 (31%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG- 417
+I+AE+G NH GD +AK++++ AK AG VKFQ T ++ KY ++ G
Sbjct: 5 YIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQ-TFKADQLISKYAPKAEYQIKVTGN 63
Query: 418 -KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 591
++ + + LE ++ +L +YA E+G+ ++ D S DFL + KI SG+
Sbjct: 64 QESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGE 122
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 65.7 bits (153), Expect = 9e-10
Identities = 42/127 (33%), Positives = 63/127 (49%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 423
+IAEVG H+G +G+A I A +AG VKFQ + + LE + KT
Sbjct: 3 VIAEVGQAHEGSLGMALSYIGALAEAGVDAVKFQVHIAEAE--SSILEPFRIKFSEQDKT 60
Query: 424 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNKL 603
D+ K +EFS +++ + K + + F AS + D L + V KIGSG+ N
Sbjct: 61 RFDYWKRMEFSTDEWKLIKKTCEDNNVEFLASPFSNAAVDLLEEVGVKRYKIGSGEVNNF 120
Query: 604 LVLKYAA 624
L+L+ A
Sbjct: 121 LLLEKIA 127
>UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratum
walsbyi DSM 16790|Rep: Sialic acid synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 391
Score = 65.7 bits (153), Expect = 9e-10
Identities = 31/115 (26%), Positives = 64/115 (55%)
Frame = +1
Query: 250 AEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKTYG 429
AE NH G+ + ++++ A DAGA +K QK ++ +T++ L +Y + +G TY
Sbjct: 98 AEFTTNHMGNFNVLMRMVEQAVDAGADYIKMQKKDVENFYTEEKLNSNY--KSPYGHTYR 155
Query: 430 DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 594
+++K EF + + + ++ I + A+ D+ S F++ +P++K+ S +S
Sbjct: 156 EYRKIFEFDRTDFDRFDEKCEDLDIEWFATPQDIKSLHFVLEYNMPYVKVASTNS 210
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 65.3 bits (152), Expect = 1e-09
Identities = 49/131 (37%), Positives = 68/131 (51%), Gaps = 3/131 (2%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG-K 420
IIAE G NH G I A +LI AA AGA VKFQ + Y N G +
Sbjct: 5 IIAEAGVNHDGKIDQALRLIDAAAAAGADVVKFQTFKAAALASAVAGRAEYQIRNLGGTE 64
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGD-S 594
+ D + LE SE + L + + GI F +S D +S +FL++ L + IK+GSG+ +
Sbjct: 65 SQLDMLRRLELSEDDHFRLRDHCRQAGIGFLSSPFDRLSLEFLIDRLGLDTIKLGSGELT 124
Query: 595 NKLLVLKYAAS 627
N L+L+ AS
Sbjct: 125 NGPLLLQAGAS 135
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 65.3 bits (152), Expect = 1e-09
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 4/149 (2%)
Frame = +1
Query: 190 LEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKF 369
++V + +G P F+IAE+ NH + AK++I AA +AGAS +K Q T +
Sbjct: 1 MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQ-TYTPDTI 59
Query: 370 TKKYLERSY---DNHNSW-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVS 537
T + D N W G++ D ++ LF YA +G++ ++ D+ +
Sbjct: 60 TLNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTA 119
Query: 538 FDFLVNLKVPFIKIGSGDSNKLLVLKYAA 624
++L L VP KI S ++N +L A
Sbjct: 120 VEYLEKLNVPCYKIASFENNDHALLAAVA 148
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 65.3 bits (152), Expect = 1e-09
Identities = 52/152 (34%), Positives = 76/152 (50%), Gaps = 9/152 (5%)
Frame = +1
Query: 196 VKITEDVKVGGNNPCFIIAEVG*NH-----QGDIG---IAKQLIKAAKDAGASCVKFQKT 351
+KI E+ ++ FI+AE G N+ +G+I AK +I+ A D+GA +KFQ T
Sbjct: 5 IKI-ENREISPTKKPFIVAEAGVNYYDIAKKGNIEPLEAAKLMIEKAADSGADAIKFQ-T 62
Query: 352 CLKEKFTKKYLERSYDNHNSWGKT-YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMD 528
E+ KY +D K+ Y KK +F E +Y+EL YA ILF ++ D
Sbjct: 63 YKAERIASKYSPAYWDVTKENTKSQYELFKKFDKFGEDEYKELAGYAANTDILFMSTPFD 122
Query: 529 MVSFDFLVNLKVPFIKIGSGDSNKLLVLKYAA 624
+ DFL L +P KI S D + + Y A
Sbjct: 123 NEAVDFLDKL-MPVFKISSSDITNIPFISYVA 153
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 64.5 bits (150), Expect = 2e-09
Identities = 42/130 (32%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
+I+AE+G NH G + IA+++I AK+AG + VKFQ T +K ++ + G+
Sbjct: 5 YIVAEIGCNHNGSVDIAREMILKAKEAGVNAVKFQ-TFKADKLISAIAPKAEYQIKNTGE 63
Query: 421 TYG--DHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 594
+ K LE Y L +YA + + ++ D S DFL +LK KI SG+
Sbjct: 64 LESQLEMTKKLEMKYDDYLHLMEYAVSLNLDVFSTPFDEDSIDFLASLKQKIWKIPSGEL 123
Query: 595 NKLLVLKYAA 624
L L+ A
Sbjct: 124 LNLPYLEKIA 133
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/116 (31%), Positives = 62/116 (53%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 423
+IAE G NH G + +A +L++ AK +GA +KFQ + + Y ++ K+
Sbjct: 5 VIAEAGVNHNGSLDLALKLVEEAKLSGADSIKFQTFKSESLASFSAPLAQYQKKSNSYKS 64
Query: 424 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 591
D K LE ++ + +F + +EIGI F +S + FL++L + IKI SG+
Sbjct: 65 QIDMLKSLELTDKDTKRIFSFCNEIGIEFMSSPFGVDELHFLLDLGMLSIKIPSGE 120
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 64.1 bits (149), Expect = 3e-09
Identities = 43/131 (32%), Positives = 59/131 (45%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+G PC++IAEVG NH GD A L+ AA AGA C KFQ L E + L D
Sbjct: 19 LGDGEPCYVIAEVGNNHNGDFDRAIALVDAAVAAGADCAKFQMRKLDEVYRASSLS-GKD 77
Query: 400 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
+ + T D + E + Q +++ Y GI + + D S L V K+
Sbjct: 78 DDLAVEYTL-DLLRRFELTTEQQKKIADYCASKGIQYLCTPWDAKSVAVLEGFGVQAYKV 136
Query: 580 GSGDSNKLLVL 612
S D L +L
Sbjct: 137 ASADLTNLPLL 147
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 61.3 bits (142), Expect = 2e-08
Identities = 39/124 (31%), Positives = 59/124 (47%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+G N+P ++IAE G +H + +A+ + A+ AGA +KFQ E T+ D
Sbjct: 11 IGPNHPPYVIAEAGVHHYDSLELARAYVLEARKAGADAIKFQTYTADELVTRWAPLYWTD 70
Query: 400 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
K+ L S ++YR LF YA E+GI ++ D S D L L + K+
Sbjct: 71 ARFETQHQVFSTKRGL--SPTEYRSLFDYARELGITPLSTPFDPASVDLLDGLGMAAFKV 128
Query: 580 GSGD 591
S D
Sbjct: 129 ASAD 132
>UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Synechococcus sp. CC9902|Rep:
N-acylneuraminate-9-phosphate synthase - Synechococcus
sp. (strain CC9902)
Length = 349
Score = 60.5 bits (140), Expect = 3e-08
Identities = 42/125 (33%), Positives = 58/125 (46%), Gaps = 4/125 (3%)
Frame = +1
Query: 229 NNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQK---TCLKEKFTKKYLERSYD 399
+NP + IA++G NH + AK LIK A ++GA KFQ + K L S
Sbjct: 7 DNPLYFIADIGANHDSSLKRAKALIKTAAESGADAAKFQNFFAHSIVSDLGFKQLPNSIL 66
Query: 400 NHNS-WGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
+H + W ++ D S EL Y E GI + + D+ +FL N V K
Sbjct: 67 SHQAEWTESVFDVYDKASLSLEWTEELHSYCKECGISYMTTPYDISILEFL-NQYVACWK 125
Query: 577 IGSGD 591
IGSGD
Sbjct: 126 IGSGD 130
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/135 (32%), Positives = 58/135 (42%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
VG + P FIIAE G NH G + A LI AA +AGA VKFQ + K Y
Sbjct: 11 VGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEAGADAVKFQMFQADRMYQKD--PGLYK 68
Query: 400 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
+ + +E L Y E ++F ++ D S D L + KI
Sbjct: 69 TAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQVIFLSTVCDEGSADLLQSTSPSAFKI 128
Query: 580 GSGDSNKLLVLKYAA 624
S + N L +LKY A
Sbjct: 129 ASYEINHLPLLKYVA 143
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/136 (30%), Positives = 59/136 (43%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+ NP F+IAE+G NH+GD A++L+ A ++GA VK Q ++ S D
Sbjct: 5 ISDKNPVFVIAEIGGNHEGDFAYARKLVSLAIESGADAVKLQVYAGDALVSR---VESPD 61
Query: 400 NHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
+ H K E S QY L G+ F ASA D + + V K
Sbjct: 62 RNR--------HFKKFELSRGQYEALIDMCRHAGVQFMASAWDRERLGW-IEPHVRIHKA 112
Query: 580 GSGDSNKLLVLKYAAS 627
GSGD +L+ S
Sbjct: 113 GSGDLTAYPMLRALVS 128
>UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.
MED297|Rep: Sialic acid synthase - Reinekea sp. MED297
Length = 354
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/133 (31%), Positives = 66/133 (49%), Gaps = 1/133 (0%)
Frame = +1
Query: 229 NNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 408
N+ F+IAE G NH GD+ +AK+LI+ A AGA +KFQ T + E ++
Sbjct: 3 NDSVFLIAEAGVNHNGDVELAKELIELAAAAGADAIKFQ-TFIPEALVTTTARKAGYQKT 61
Query: 409 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 588
+ ++ + L + EL YA I F ++A + S L L V KI SG
Sbjct: 62 AHEESQLAMLQALALPLPVFDELKAYADSKAIEFMSTAFESESLALLSQLAVRRYKIPSG 121
Query: 589 D-SNKLLVLKYAA 624
+ +N ++++AA
Sbjct: 122 ELTNLPFLIEHAA 134
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/143 (32%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFT----KKYL 384
K+G FIIAE+ NH D A ++IKAAK +GA +K Q T + T +Y
Sbjct: 11 KIGEGQRTFIIAEMSANHNQDFDRAVEIIKAAKRSGADAIKLQ-TYTPDTITFDSDNEYF 69
Query: 385 ERSYDNHNSWGKTYGDHKKHLE-FSESQYR-ELFKYAHEIGILFTASAMDMVSFDFLVNL 558
+ W T HK + E ++ Q++ +L + A E G++ +S D S DFL +
Sbjct: 70 Q--IKQGTIWDGT-TLHKLYEEAYTPWQWQPKLKEIAEEEGLICFSSPFDNTSVDFLEKM 126
Query: 559 KVPFIKIGSGDSNKLLVLKYAAS 627
+VP K+ S + + ++Y AS
Sbjct: 127 EVPAYKVASFELTDIPFIEYIAS 149
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 56.8 bits (131), Expect = 4e-07
Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+G ++IAE+ NH G++ A ++ AAK AGAS VK Q T + T K +
Sbjct: 8 IGPAQAPYVIAELSANHNGNLERALAIMTAAKAAGASAVKLQ-TYRPDTITLKSDRPEFQ 66
Query: 400 NHNS-W-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFI 573
H W G + D + ++ LF E+G+ +S D + D L +L P
Sbjct: 67 IHGGLWDGHSLYDLYEWAHTPWEWHQALFAKGRELGLTVFSSPFDFSAVDLLESLDCPAY 126
Query: 574 KIGSGDSNKLLVLKYAA 624
KI S + L +++YAA
Sbjct: 127 KIASFELVDLPLIRYAA 143
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 56.0 bits (129), Expect = 7e-07
Identities = 48/121 (39%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKE---KFTKK--YLERSYDNH 405
FIIAE G NH GDI AK+LI A +A A VKFQ E +F K YLE + +
Sbjct: 14 FIIAEAGVNHDGDIQRAKRLIDVAAEAQADAVKFQTWRPGEITGRFAYKVNYLEATTEQA 73
Query: 406 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLV-NLKVPFIKIG 582
S Y + L +REL + GILF ++ S FLV L +P +KIG
Sbjct: 74 ES---RY-ELSCRLALPYPVFRELKSHCEARGILFLSTPDGFDSLAFLVGELDMPIVKIG 129
Query: 583 S 585
S
Sbjct: 130 S 130
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 55.6 bits (128), Expect = 9e-07
Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 2/131 (1%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY-DNHNSW- 414
+IIAE+ NH GD+ AK+ I A + G S +K Q T + T L+ + W
Sbjct: 15 YIIAELSANHGGDLSRAKESITKAAEVGVSAIKIQ-TYTPDTMTLDSLQDDFIVKDGLWA 73
Query: 415 GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 594
G++ + + ELF +A G+ ++ D + D L +L P KI S +
Sbjct: 74 GRSLYELYTEAYTPYEWHEELFNHAKNCGVTIFSTPFDETAVDLLESLNTPAYKIASFEI 133
Query: 595 NKLLVLKYAAS 627
L ++KY AS
Sbjct: 134 VDLPLVKYIAS 144
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 55.2 bits (127), Expect = 1e-06
Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 2/139 (1%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
K+G ++ ++I E+ NH G + ++ AA D G +K Q T + T +
Sbjct: 18 KIGADHSPYVICELSGNHNGSLERCLAMVDAAADTGCDAIKIQ-TYTADTITLDVDRPEF 76
Query: 397 DNHNS-W-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPF 570
H W G+T + + + +F+ A + G+ +S D + D L +L P
Sbjct: 77 KIHGGLWDGRTLYELYEEAHTPFEWHAAIFERARQRGVTIFSSPFDETAVDLLDSLGAPA 136
Query: 571 IKIGSGDSNKLLVLKYAAS 627
KI S ++ L ++KYAA+
Sbjct: 137 FKIASFEAVDLPLIKYAAA 155
>UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4;
Bacteria|Rep: N-acetylneuraminate synthase -
Neptuniibacter caesariensis
Length = 363
Score = 55.2 bits (127), Expect = 1e-06
Identities = 41/144 (28%), Positives = 65/144 (45%), Gaps = 3/144 (2%)
Frame = +1
Query: 202 ITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQ---KTCLKEKFT 372
I + ++P + IA++ NH GD+ AK+LI + +AGA KFQ + F
Sbjct: 11 IVNSHSISESDPTYFIADIAANHDGDLEKAKELIWLSAEAGADAAKFQHFKADTIVSDFG 70
Query: 373 KKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLV 552
K L + ++W K+ + E + EL + I F S D D+ +
Sbjct: 71 FKSLGGQQSHQSTWEKSVYEVYADAEVDLNWTEELVNTCKQAEIDFFTSPYDFDLADY-I 129
Query: 553 NLKVPFIKIGSGDSNKLLVLKYAA 624
+ VP KIGSGD +L++ A
Sbjct: 130 DQFVPAHKIGSGDITWHAMLEHIA 153
>UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid
synthetase NeuB; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similarity to N-acetyl neuramic
acid synthetase NeuB - Candidatus Kuenenia
stuttgartiensis
Length = 277
Score = 54.8 bits (126), Expect = 2e-06
Identities = 42/121 (34%), Positives = 56/121 (46%)
Frame = +1
Query: 229 NNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 408
+N ++IAE+G NH GD+ AK+LI +A G VKFQ T L EK K N
Sbjct: 12 DNKVYVIAEIGLNHGGDMNTAKRLIDSASKTGVDAVKFQ-TYLTEKRVPK---------N 61
Query: 409 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 588
S D K E ++EL Y I F ++ D S DFL ++ K+ S
Sbjct: 62 S---PIFDILKKCELPFEVFKELKDYTETYNIEFFSTPFDEESVDFLESVNCALYKVASF 118
Query: 589 D 591
D
Sbjct: 119 D 119
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 4/132 (3%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
FIIAE+ NH D +AK +I+AA G +K Q T + T +
Sbjct: 11 FIIAELSGNHNQDFALAKAMIEAAAKTGVDAIKLQ-TYTADSMTLNVRNEEFMVSAQGSL 69
Query: 421 TYGDHKKHLEFSESQ----YRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 588
GD+ L S ++ LF YA +G++ +S D+ + +FL +L VP KI S
Sbjct: 70 WEGDNLYDLYAKASTPYEWHQPLFDYAKSLGLVAFSSPFDINAVNFLESLDVPIYKIASF 129
Query: 589 DSNKLLVLKYAA 624
+ L +++ A
Sbjct: 130 ELTDLPLIEAVA 141
>UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Proteobacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Marinomonas sp. MWYL1
Length = 343
Score = 54.4 bits (125), Expect = 2e-06
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 4/132 (3%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY---DNHNS 411
FIIAE+ NH D +AK +I AA +AG +K Q T + T + ++ +
Sbjct: 11 FIIAELSGNHDQDFELAKAMIHAAAEAGVDAIKLQ-TYTPDTMTLDVRHGEFMVSESDSL 69
Query: 412 W-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 588
W G D K ++ LF+ A +G++ +S D+ + FL ++ VP KI S
Sbjct: 70 WRGSNLYDLYKKASTPWEWHKPLFELAESLGLVAFSSPFDLSAVAFLESIDVPLYKIASF 129
Query: 589 DSNKLLVLKYAA 624
+ + +++ A
Sbjct: 130 EMTDIPLIQAVA 141
>UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 352
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/137 (24%), Positives = 67/137 (48%)
Frame = +1
Query: 217 KVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSY 396
++G ++ ++AE+G NH+G + A +++ AA AGA +K Q ++++ + +
Sbjct: 17 EIGYDHDPVVVAEIGINHEGSLETAYEMVDAAVSAGAEIIKHQTHVVEDEMSAD--AKKV 74
Query: 397 DNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIK 576
N+ Y + + +E +L +Y G +F ++ + + L + V K
Sbjct: 75 IPGNADVSIY-EIMERCALNEEDETKLKEYVESKGAIFISTPFSRAAAERLERMGVEAYK 133
Query: 577 IGSGDSNKLLVLKYAAS 627
IGSG+ N +L+ AS
Sbjct: 134 IGSGECNNYPLLELVAS 150
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/132 (29%), Positives = 62/132 (46%)
Frame = +1
Query: 229 NNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHN 408
+NP +IIAE+G H G G A +L++ A + GA VKFQ + + SY +
Sbjct: 5 SNP-YIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQTHIAEAETLPNAPSPSYFS-- 61
Query: 409 SWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSG 588
+ + K FS Q+R L A + F +S + + D L ++ V KI SG
Sbjct: 62 --AEPRTAYFKRTGFSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSG 119
Query: 589 DSNKLLVLKYAA 624
+ + + +L A
Sbjct: 120 EVSNIPLLSRIA 131
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 50.0 bits (114), Expect = 5e-05
Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 3/149 (2%)
Frame = +1
Query: 187 MLEVKITEDVK-VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKE 363
M + IT D + +G +IIAE+ NH+G + A +I AA +G +K Q T
Sbjct: 1 MFKASITIDGRHIGPEYQPYIIAELSGNHKGSLSQALAMIDAAAASGVDAIKIQ-TYTAN 59
Query: 364 KFTKKYLERSYD-NHNSW-GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVS 537
T ++ + N W G+T D + ++ LF++A + + +S D+ +
Sbjct: 60 TITLQHDGPEFRINGGLWKGRTLFDLYEEAHTPWEWHKSLFEHAKKQNVTLFSSPFDLKA 119
Query: 538 FDFLVNLKVPFIKIGSGDSNKLLVLKYAA 624
+ L + + P KI S + N + ++ AA
Sbjct: 120 IELLESCECPAYKISSFEINDIGLIMAAA 148
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
Frame = +1
Query: 238 CFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWG 417
C +I E+G NH + +LI AG +K Q+ +++ + Y G
Sbjct: 16 CIVIGEIGVNHNRQQDMLFRLIDEGIAAGLDVIKLQRFKAEQEIAMQAPAADYQKRAGAG 75
Query: 418 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVN-LKVPFIKIGSGD- 591
++ + LE ++ + F Y + G+ F +A D S DFL + L +KI S +
Sbjct: 76 ESQLQMARQLELPDAWLTQAFDYCRQRGVGFLCTAFDHGSVDFLADRLGCKTVKIPSPEV 135
Query: 592 SNKLLV 609
SNK L+
Sbjct: 136 SNKPLL 141
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 49.2 bits (112), Expect = 8e-05
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 3/138 (2%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQK-TCLKEKFTKKYLERSY 396
+ N+ F+IAE+ NH + A ++ AA AGA +K Q T F E
Sbjct: 9 ISENHKPFVIAEMSGNHNQSLDRALAIVDAAAAAGAHALKLQTYTADTITFNGTSDEFII 68
Query: 397 DNHNSWGKTYGDHKKHLE-FSESQYR-ELFKYAHEIGILFTASAMDMVSFDFLVNLKVPF 570
+ NS K H+ + + ++ ++ +F+ A G++ +S D + DFL +L VP
Sbjct: 69 KDENSIWKNQNLHQLYQQAYTPWEWHAPIFERAKSHGMIAFSSPFDTTAVDFLESLDVPC 128
Query: 571 IKIGSGDSNKLLVLKYAA 624
KI S ++ ++LK A
Sbjct: 129 YKIASFENTDHILLKKVA 146
>UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Geobacter bemidjiensis Bem|Rep:
N-acylneuraminate-9-phosphate synthase - Geobacter
bemidjiensis Bem
Length = 338
Score = 48.8 bits (111), Expect = 1e-04
Identities = 39/131 (29%), Positives = 59/131 (45%)
Frame = +1
Query: 235 PCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSW 414
P +IIAE+G N AK L+ AA G VK Q T E + K +D N+
Sbjct: 10 PIYIIAEIGGNFT-TFEEAKALVDAAASCGVDAVKLQ-TYRAETVSSK--SAIFDMENTG 65
Query: 415 GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 594
+ + + E E +R++F Y G+ + ++ D L L V KIGS D+
Sbjct: 66 IASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDA 125
Query: 595 NKLLVLKYAAS 627
+ L+Y A+
Sbjct: 126 VNIPFLRYVAA 136
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 48.4 bits (110), Expect = 1e-04
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 4/131 (3%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQ---KTCLKEKFTKKYLERSYDNHNSW 414
IIAE+G NH GDI A +I K+ G VKFQ + K +K Y + + + S
Sbjct: 23 IIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTMSQ 82
Query: 415 GKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD- 591
+ + + K F +++++ Y +LF ++ D S ++ +N K+ S D
Sbjct: 83 FELFSKYDK---FGLEEFKKIEDYCKRKSVLFMSTPFDSYSANY-INQLSKIHKVASVDI 138
Query: 592 SNKLLVLKYAA 624
+N +L+ + A+
Sbjct: 139 TNHILISQLAS 149
>UniRef50_UPI0000E87B4B Cluster: putative N-acetyl neuramic acid
synthetase NeuB; n=1; Methylophilales bacterium
HTCC2181|Rep: putative N-acetyl neuramic acid synthetase
NeuB - Methylophilales bacterium HTCC2181
Length = 615
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/39 (56%), Positives = 27/39 (69%)
Frame = +1
Query: 229 NNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQ 345
+ P FIIAE+G NH GD IA +LIKAA A + +KFQ
Sbjct: 7 SKPIFIIAEIGINHGGDFSIALELIKAAAQAKVNGIKFQ 45
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/116 (28%), Positives = 58/116 (50%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 423
+IAE+G NH GD+ AK+ I+A+ AGA VKFQ T +E +++ + D +
Sbjct: 6 VIAEIGSNHGGDLDQAKRYIEASAKAGADVVKFQ-TLTREGLIARFV-KGADGTVTENPK 63
Query: 424 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 591
+ + + + L A + G+ F ++ + + + + +L V KI SGD
Sbjct: 64 FAAF-GNAGLPDDWHAPLMTCAADNGVEFMSTPFSLDAVELMESLGVKRYKIASGD 118
>UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6;
Helicobacter|Rep: Sialic acid synthase - Helicobacter
hepaticus
Length = 349
Score = 46.4 bits (105), Expect = 6e-04
Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 423
IIAE+ NH + IAK I+A GA VK Q T E T L+ + + G T
Sbjct: 15 IIAELSANHNQSLEIAKDSIRAIAACGADGVKLQ-TYTPECLT---LQSNEPHFCISGGT 70
Query: 424 YGDHKKHLE-FSESQ-----YRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 585
D + E + E+Q ++ELF A E+G+L +S FL +L+ P K+ S
Sbjct: 71 LWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKVAS 130
>UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep:
Pse synthetase - Campylobacter jejuni
Length = 343
Score = 43.2 bits (97), Expect = 0.005
Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 6/125 (4%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
FIIAE+ NH G + +A + IKAAK AGA +K Q T + T L ++ G
Sbjct: 13 FIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQ-TYTPDSLT---LNSDKEDFIIKGG 68
Query: 421 TYGDHKKHLEFSESQ------YRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIG 582
+ D +K E ES + ++F+ A GIL +S +FL KI
Sbjct: 69 LW-DKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIA 127
Query: 583 SGDSN 597
S ++N
Sbjct: 128 SFEAN 132
>UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: NeuB family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 358
Score = 41.9 bits (94), Expect = 0.012
Identities = 37/127 (29%), Positives = 55/127 (43%)
Frame = +1
Query: 244 IIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKT 423
IIAEVG NH GD +A ++I++A + GA VK Q F L H S
Sbjct: 24 IIAEVGLNHGGDADLAWEMIESAWEHGADLVKLQ------SFAPGGL-----LHPS--LP 70
Query: 424 YGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNKL 603
Y + + S Q+ LF+ A GI + D + D ++ +K+ S D +
Sbjct: 71 YAASMEGMMLSLRQHEALFERARRQGIALITTPFDAPTLDLCTRFRIAAVKVASMDLDNT 130
Query: 604 LVLKYAA 624
L+ A
Sbjct: 131 AHLRAVA 137
>UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Chlorobium ferrooxidans DSM 13031
Length = 354
Score = 41.9 bits (94), Expect = 0.012
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 6/141 (4%)
Frame = +1
Query: 220 VGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYD 399
+G +P FI+AE+ NH G + A +++ AAK +GA +K Q T + T + +
Sbjct: 15 LGPGHPAFIVAEMSGNHGGSLEYALEIVHAAKRSGADAIKLQ-TYTADTITLNSDRQDFC 73
Query: 400 NHNSWGKTYGDHKKHLEFSESQY------RELFKYAHEIGILFTASAMDMVSFDFLVNLK 561
+ G + DH Y +F+ A + + +S D + + L L
Sbjct: 74 IPS--GTPWADHSTLWSLYNKAYTPWDWHESIFREARSLDLEIFSSPFDESAVELLEQLG 131
Query: 562 VPFIKIGSGDSNKLLVLKYAA 624
KI S + + +L A
Sbjct: 132 ASAYKIASPEITHIPLLDKVA 152
>UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis
protein; n=1; Treponema pallidum|Rep: Spore coat
polysaccharide biosynthesis protein - Treponema pallidum
Length = 378
Score = 40.7 bits (91), Expect = 0.028
Identities = 37/117 (31%), Positives = 50/117 (42%)
Frame = +1
Query: 247 IAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKTY 426
IAE+G H G A+ LI AA DA A+ VKFQ E L + + Y
Sbjct: 18 IAEIGSAHAGSFDRARALIDAAADAAAAAVKFQLIYAHEILHP--LTGAVRLPSGAVSLY 75
Query: 427 GDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 597
+ LE S Y + F +A G+L S S + LK F+K+ S + N
Sbjct: 76 -QRFEELEVPLSFYAQCFNHARSRGMLVGISPFGPRSATEALALKPDFLKVASPELN 131
>UniRef50_Q88Z00 Cluster: Non-ribosomal peptide synthetase NpsB;
n=1; Lactobacillus plantarum|Rep: Non-ribosomal peptide
synthetase NpsB - Lactobacillus plantarum
Length = 805
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Frame = +1
Query: 355 LKEKFTKK-YLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHEI-GILFTASAMD 528
L EK T K + SY N N WG GD+ K L E +YR ++I G+ S +
Sbjct: 326 LNEKATNKAFTSVSYQNQNIWGYRTGDYAKVLPNGELEYRGRRDSQYKINGVRIDLSEVG 385
Query: 529 MVSFDFLVNLKVPFIKI 579
V + + NLK ++ +
Sbjct: 386 SVCREIIPNLKQCYLAV 402
>UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1;
Neptuniibacter caesariensis|Rep: N-acetylneuraminic acid
synthetase - Neptuniibacter caesariensis
Length = 270
Score = 37.9 bits (84), Expect = 0.20
Identities = 34/127 (26%), Positives = 59/127 (46%)
Frame = +1
Query: 247 IAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGKTY 426
IAE+G N GD+ +A+ +I AA +GA+ KFQ +K ++DN G+
Sbjct: 4 IAEIGWNFMGDMKLAEDMIAAAAQSGATTAKFQYW-----NPEKLKAGAWDND---GRRE 55
Query: 427 GDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNKLL 606
+K L + Q +L + + + F S + +F+ IKI S + +
Sbjct: 56 IYNKACLNADKIQ--QLTELCSKHNVKFLLSVFNKEDAEFVSQFSTEAIKIPSHEVANIE 113
Query: 607 VLKYAAS 627
+++YA S
Sbjct: 114 LIRYALS 120
>UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis
related-protein; n=6; Proteobacteria|Rep: Polysaccharide
biosynthesis related-protein - Shewanella oneidensis
Length = 290
Score = 37.5 bits (83), Expect = 0.26
Identities = 21/55 (38%), Positives = 30/55 (54%)
Frame = +1
Query: 229 NNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERS 393
++P FI AEV NH D+ + IK A + G VKFQ ++E F + L +S
Sbjct: 4 HSPLFI-AEVSSNHHRDLQRCIEFIKTAAEIGCDAVKFQLFKIEELFAPEILSKS 57
>UniRef50_A2ENS5 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1602
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +1
Query: 43 PYLFDLILKGRSINLLLRSDSLFPSDPA*TGTRFSFVCFYGTLVVVLNMLEVKITE 210
P+LF LI KG+ ++ +LR+ SLF S+ F F ++ VL+ L VK T+
Sbjct: 552 PFLFKLITKGKEVDEILRNLSLFVSE---NNIPFDISTFLTAILYVLSCLNVKSTD 604
>UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 351
Score = 37.1 bits (82), Expect = 0.34
Identities = 36/133 (27%), Positives = 55/133 (41%), Gaps = 5/133 (3%)
Frame = +1
Query: 241 FIIAEVG*N-----HQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNH 405
F+IAE G N + D+ AK+LI+ A AGA VKFQ + + Y
Sbjct: 14 FVIAEAGSNWKCGDYSDDLEQAKKLIETAAKAGADAVKFQTYKPETIYVSDAGNSDYLEK 73
Query: 406 NSWGKTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKIGS 585
+ + +HL EL KY E I F ++ V V+ K+ S
Sbjct: 74 YGIKENINEIFEHLSMPYEMIPELKKYCDEKNIQFMSTPFS-VQDAKEVDKFTEIHKVAS 132
Query: 586 GDSNKLLVLKYAA 624
+ N + +L++ A
Sbjct: 133 FEINHIRLLEFLA 145
>UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus
sp. CC9311|Rep: NeuB family protein - Synechococcus sp.
(strain CC9311)
Length = 353
Score = 36.3 bits (80), Expect = 0.60
Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 5/153 (3%)
Frame = +1
Query: 181 LNMLEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLK 360
+++ ++ I V G+ P I+ ++ GD+ IA+ LI++ +G +K T +
Sbjct: 1 MSLRDICIGTQVLGEGHLP-IILPDIDMFFNGDLEIARGLIESVSKSGLRTIK---TAIL 56
Query: 361 EK----FTKKYLERSYDNHNSWGKT-YGDHKKHLEFSESQYRELFKYAHEIGILFTASAM 525
E F ER S+ Y + + Q+RELF G+ F S
Sbjct: 57 EDPMVVFDTPAEERYLCRDGSYKSVNYRSLIQKKVMTLDQHRELFNLIKSYGLNFIVSVY 116
Query: 526 DMVSFDFLVNLKVPFIKIGSGDSNKLLVLKYAA 624
+ S DF V+ IKI S + N L +++ +A
Sbjct: 117 TLESVDFAVSEGAIAIKIASSNINFLPLIEKSA 149
>UniRef50_Q2AHF7 Cluster: Antifreeze-like; n=1; Halothermothrix
orenii H 168|Rep: Antifreeze-like - Halothermothrix
orenii H 168
Length = 350
Score = 35.9 bits (79), Expect = 0.79
Identities = 30/103 (29%), Positives = 45/103 (43%)
Frame = +1
Query: 241 FIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNSWGK 420
+II E NHQGDI K++I + G VKF E YL+ + H K
Sbjct: 4 YIIGETAYNHQGDIHYLKRMIDDIAEIGLQAVKFHLLLNPE----SYLQ---NKHPLIKK 56
Query: 421 TYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFL 549
K F+E ++ E+ Y+ + G+ A D+ S F+
Sbjct: 57 I-----KEWIFTEKEWDEIINYSKQKGLDMIALCDDLDSLKFI 94
>UniRef50_UPI0000E117D8 Cluster: Na(+)-translocating NADH-quinone
reductase subunit A; n=1; alpha proteobacterium
HTCC2255|Rep: Na(+)-translocating NADH-quinone reductase
subunit A - alpha proteobacterium HTCC2255
Length = 68
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/53 (35%), Positives = 32/53 (60%)
Frame = +2
Query: 341 SKRLASRRNSRKSI*SALMIITILGVKLMVITKNIWNFLKVNTVNYSNMLTRS 499
SK + N + ++ A ++IT+ VK+M +T+NI + L VN++N N L S
Sbjct: 13 SKTFYNNNNIQAAMCDAPLLITVAFVKMMGLTQNITSQLSVNSLNRVNNLKTS 65
>UniRef50_UPI000038CA6C Cluster: COG5295: Autotransporter adhesin;
n=1; Nostoc punctiforme PCC 73102|Rep: COG5295:
Autotransporter adhesin - Nostoc punctiforme PCC 73102
Length = 829
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/60 (40%), Positives = 33/60 (55%)
Frame = +1
Query: 163 GTLVVVLNMLEVKITEDVKVGGNNPCFIIAEVG*NHQGDIGIAKQLIKAAKDAGASCVKF 342
GT V+LN +V ITED GGNN + N Q D ++ +AKD+GAS ++F
Sbjct: 728 GTGNVILNANKVVITEDGTAGGNNWAL---DNDNNTQID---TSNIVGSAKDSGASTIQF 781
>UniRef50_A5AVR4 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 441
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/55 (27%), Positives = 29/55 (52%)
Frame = +1
Query: 247 IAEVG*NHQGDIGIAKQLIKAAKDAGASCVKFQKTCLKEKFTKKYLERSYDNHNS 411
+ E +H D+ + + L+ KD AS + + +T E F + ++ S+D HN+
Sbjct: 262 VLETPLSHMLDLNLCRPLLXICKDHHASSLSWVETLEIEDFCRDFIVMSFDQHNN 316
>UniRef50_Q54Y66 Cluster: Small GTPase; n=2; Dictyostelium
discoideum AX4|Rep: Small GTPase - Dictyostelium
discoideum AX4
Length = 208
Score = 33.1 bits (72), Expect = 5.6
Identities = 21/54 (38%), Positives = 31/54 (57%)
Frame = +1
Query: 418 KTYGDHKKHLEFSESQYRELFKYAHEIGILFTASAMDMVSFDFLVNLKVPFIKI 579
K GD+ K+L F+E++ +EL KY + I ASA D+ S + NL + I I
Sbjct: 123 KVDGDNNKNLAFTETEIQELSKYINLPYI--EASAKDIRSVQSIFNLLIDTINI 174
>UniRef50_UPI0000499648 Cluster: hypothetical protein 263.t00006;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 263.t00006 - Entamoeba histolytica HM-1:IMSS
Length = 315
Score = 32.7 bits (71), Expect = 7.4
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +1
Query: 265 NHQGDIGIAKQLIKAAKDAGASCV---KFQKTCLKEKFTKKYLERSYDNHNSWGKTYGDH 435
N+ +I + + LI+ K C + K +KE+ TKKYL++ D + K +
Sbjct: 96 NNTLNIEVQRYLIEKMKKTNNDCTINDEVIKELIKEEITKKYLQKIKDEIENNKKEKNNP 155
Query: 436 KKHLEFSESQYRELFKYAHEI 498
+ E Y + K H I
Sbjct: 156 SNNNPIEEQPYNNVAKQPHNI 176
>UniRef50_Q54LZ9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 307
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Frame = +1
Query: 334 VKFQKTCLKEKFTKKYLERSYDNHNSWGKTYGDHKKH---LEFSESQYRELFKYAHEIGI 504
+K K C K +FTK + E D+ ++W KT + +K + SE + F ++G
Sbjct: 11 IKKLKDCDKNEFTKLWNESHSDHFHNWQKTREEIEKRNKLYKLSEENSKVAFIDDKQVGF 70
Query: 505 LFTAS 519
+ TA+
Sbjct: 71 ILTAT 75
>UniRef50_Q7MVQ9 Cluster: Putative uncharacterized protein; n=1;
Porphyromonas gingivalis|Rep: Putative uncharacterized
protein - Porphyromonas gingivalis (Bacteroides
gingivalis)
Length = 258
Score = 32.3 bits (70), Expect = 9.8
Identities = 14/46 (30%), Positives = 24/46 (52%)
Frame = +1
Query: 358 KEKFTKKYLERSYDNHNSWGKTYGDHKKHLEFSESQYRELFKYAHE 495
KEK+ ++Y++ + W K ++ +E + QYRE K A E
Sbjct: 187 KEKYYQEYMKAQKKQNQEWRKEREKLRREMEKARKQYREEMKKARE 232
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 632,984,792
Number of Sequences: 1657284
Number of extensions: 12758342
Number of successful extensions: 31377
Number of sequences better than 10.0: 90
Number of HSP's better than 10.0 without gapping: 30351
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31332
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46051731393
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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