Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= S06A01NCLL0002_F02
(249 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4T5P0 Cluster: Malic enzyme; n=1; Tetraodon nigrovirid... 89 2e-17
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 86 2e-16
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 85 4e-16
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 84 7e-16
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 70 1e-11
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 69 3e-11
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 69 3e-11
UniRef50_Q5C370 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 64 4e-10
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 62 2e-09
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 62 2e-09
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 62 2e-09
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 60 7e-09
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 60 9e-09
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 59 2e-08
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 55 3e-07
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 50 1e-05
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 50 1e-05
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 50 1e-05
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 49 2e-05
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 49 2e-05
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 49 2e-05
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 48 3e-05
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 48 5e-05
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 46 1e-04
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 46 2e-04
UniRef50_Q9HKY7 Cluster: Malate oxidoreductase (Malic enzyme) re... 45 3e-04
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 44 5e-04
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 44 5e-04
UniRef50_A5B3Q7 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 44 6e-04
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 43 0.001
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 42 0.003
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 42 0.003
UniRef50_Q3VJ13 Cluster: Malate dehydrogenase; n=4; Chlorobium/P... 42 0.003
UniRef50_A7R628 Cluster: Chromosome undetermined scaffold_1141, ... 42 0.003
UniRef50_Q5Y0M3 Cluster: Malate oxidoreductase; n=8; cellular or... 41 0.005
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 41 0.006
UniRef50_A5AG28 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 40 0.008
UniRef50_Q8U225 Cluster: Malate oxidoreductase; n=41; cellular o... 40 0.008
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 40 0.008
UniRef50_Q81NN6 Cluster: Malate dehydrogenase, putative; n=7; ce... 40 0.011
UniRef50_Q2KKD0 Cluster: Oxalacetate decarboxylase; n=11; Lactob... 40 0.011
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 40 0.011
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 40 0.011
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 40 0.014
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 39 0.018
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 39 0.024
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 39 0.024
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 39 0.024
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 38 0.032
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 38 0.043
UniRef50_Q9YF49 Cluster: Malate dehydrogenase; n=3; Archaea|Rep:... 38 0.043
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 38 0.056
UniRef50_Q27113 Cluster: Malic enzyme; n=1; Trichomonas vaginali... 37 0.074
UniRef50_Q73JN6 Cluster: Malate dehydrogenase; n=3; cellular org... 37 0.098
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 37 0.098
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 36 0.17
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 36 0.23
UniRef50_A4M6V5 Cluster: Malate dehydrogenase; n=2; Thermotogace... 36 0.23
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 36 0.23
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 36 0.23
UniRef50_A0K0I7 Cluster: Malate dehydrogenase; n=87; cellular or... 35 0.30
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 35 0.30
UniRef50_O30808 Cluster: NADP-dependent malic enzyme; n=132; cel... 35 0.30
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 35 0.40
UniRef50_A7DL10 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 34 0.52
UniRef50_Q7MXC5 Cluster: NADP-dependent malic enzyme; n=1; Porph... 34 0.69
UniRef50_P16468 Cluster: NAD-dependent malic enzyme; n=32; Bacte... 33 0.92
UniRef50_A6H1G1 Cluster: Malate dehydrogenase; n=3; Bacteria|Rep... 33 1.2
UniRef50_A1GDI9 Cluster: Putative uncharacterized protein; n=1; ... 32 2.8
UniRef50_A6PP44 Cluster: Putative uncharacterized protein; n=1; ... 31 3.7
UniRef50_Q7VH73 Cluster: Malate oxidoreductase; n=1; Helicobacte... 31 4.9
UniRef50_Q3W7J3 Cluster: Malate dehydrogenase; n=1; Frankia sp. ... 31 4.9
UniRef50_Q3JAT5 Cluster: Malate dehydrogenase; n=1; Nitrosococcu... 31 6.5
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 31 6.5
UniRef50_A5NQD6 Cluster: Cobalamin B12-binding domain protein; n... 30 8.5
UniRef50_A7RUG2 Cluster: Predicted protein; n=1; Nematostella ve... 30 8.5
>UniRef50_Q4T5P0 Cluster: Malic enzyme; n=1; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 306
Score = 89.0 bits (211), Expect = 2e-17
Identities = 47/75 (62%), Positives = 54/75 (72%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAVAVAGL+A+LRIT K+S + IVFQGAGEA++GIAEL MAMK
Sbjct: 36 IQGTAAVAVAGLLAALRITETKMSDHTIVFQGAGEAAMGIAELITMAMKKEGLPEQECLK 95
Query: 189 XIWMVDSRWLIVKNR 233
IWMVDS+ LIVK R
Sbjct: 96 KIWMVDSKGLIVKGR 110
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 85.8 bits (203), Expect = 2e-16
Identities = 44/75 (58%), Positives = 54/75 (72%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TA+VAVAG++A+LRIT KLS +V VFQGAGEA++GIA L VMA++
Sbjct: 305 IQGTASVAVAGILAALRITNNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATR 364
Query: 189 XIWMVDSRWLIVKNR 233
IWMVDS+ LIVK R
Sbjct: 365 KIWMVDSKGLIVKGR 379
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 84.6 bits (200), Expect = 4e-16
Identities = 44/75 (58%), Positives = 53/75 (70%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TA+VAVAGL+A+LRIT KLS ++FQGAGEA+LGIA L VMAM+
Sbjct: 270 IQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARK 329
Query: 189 XIWMVDSRWLIVKNR 233
IW+VDS+ LIVK R
Sbjct: 330 KIWLVDSKGLIVKGR 344
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 83.8 bits (198), Expect = 7e-16
Identities = 44/75 (58%), Positives = 53/75 (70%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TA+VAVAGL+A+LRIT KLS I+FQGAGEA+LGIA L VMA++
Sbjct: 270 IQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIK 329
Query: 189 XIWMVDSRWLIVKNR 233
IW+VDS+ LIVK R
Sbjct: 330 KIWLVDSKGLIVKGR 344
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 69.7 bits (163), Expect = 1e-11
Identities = 38/75 (50%), Positives = 46/75 (61%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAVA+AGL + LRI+G KL I+F GAGEA+ GIA+L V AM
Sbjct: 253 IQGTAAVALAGLFSGLRISGGKLKDQKILFLGAGEAATGIADLVVSAMMAEGATEAEALR 312
Query: 189 XIWMVDSRWLIVKNR 233
W+VDSR L+V R
Sbjct: 313 RNWLVDSRGLVVSGR 327
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 68.5 bits (160), Expect = 3e-11
Identities = 36/76 (47%), Positives = 47/76 (61%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAVA+AG+I++L TG KL+ ++F GAGEA GIA+L V A +
Sbjct: 278 IQGTAAVALAGVISALNSTGGKLADQKLLFLGAGEAGTGIADLFVAAAREAGLSEEQARA 337
Query: 189 XIWMVDSRWLIVKNRP 236
W VDS+ L+VK RP
Sbjct: 338 RCWFVDSQGLVVKTRP 353
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 68.5 bits (160), Expect = 3e-11
Identities = 36/75 (48%), Positives = 48/75 (64%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAVA+AGL+A+ ++ K +S++ I+F GAGEA+LGIA L VM+M
Sbjct: 280 IQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQK 339
Query: 189 XIWMVDSRWLIVKNR 233
IWM D L+VK R
Sbjct: 340 KIWMFDKYGLLVKGR 354
>UniRef50_Q5C370 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 264
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/75 (46%), Positives = 47/75 (62%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ +A V V+GL+ + RIT KK+SQN +F G+G AS+GIA L V A+
Sbjct: 55 IQGSAVVIVSGLLTASRITKKKISQNTYLFYGSGGASIGIARLLVQAIIEEGFTEDEAKS 114
Query: 189 XIWMVDSRWLIVKNR 233
I+M+DSR L+V NR
Sbjct: 115 RIFMMDSRGLLVTNR 129
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 62.5 bits (145), Expect = 2e-09
Identities = 31/75 (41%), Positives = 48/75 (64%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAV V+GL+AS+R G ++Q ++F GAG+A++G AEL V A+
Sbjct: 302 IQGTAAVTVSGLLASVRSLGGDVTQQRVLFFGAGQANIGAAELFVSALVQRGVSEEEAKK 361
Query: 189 XIWMVDSRWLIVKNR 233
+W+ DS+ L+V++R
Sbjct: 362 RVWLFDSKGLVVRSR 376
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 62.5 bits (145), Expect = 2e-09
Identities = 32/78 (41%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAM-KXXXXXXXXXX 185
IQ TA+V +AGL++SL++ G L+++ +F GAGEA GIAEL + + K
Sbjct: 355 IQGTASVVLAGLLSSLKVVGGTLAEHTYLFLGAGEAGTGIAELIALEISKQTKAPIEECR 414
Query: 186 XXIWMVDSRWLIVKNRPE 239
+W++DS+ LIV +R E
Sbjct: 415 KKVWLLDSKGLIVNSRKE 432
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 62.1 bits (144), Expect = 2e-09
Identities = 32/78 (41%), Positives = 46/78 (58%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAA+ +A L++SLR T KL ++F GAGEA +GI EL MAM+
Sbjct: 248 IQGTAAITLAALLSSLRATKGKLEDQKVLFYGAGEAGVGIGELIAMAMEKTGMSHKEAME 307
Query: 189 XIWMVDSRWLIVKNRPEG 242
+ +DS+ L+ K+R +G
Sbjct: 308 RCYFMDSKGLVCKSRLDG 325
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 60.5 bits (140), Expect = 7e-09
Identities = 32/76 (42%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAM-KXXXXXXXXXX 185
IQ TA+V +AGL+A+L++ G L++ +F GAGEA GIAEL + + K
Sbjct: 352 IQGTASVVLAGLLAALKMVGGTLAEQTYLFLGAGEAGTGIAELIALEISKQTNAPIEECR 411
Query: 186 XXIWMVDSRWLIVKNR 233
+W+VDS+ LIV +R
Sbjct: 412 KKVWLVDSKGLIVDSR 427
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 60.1 bits (139), Expect = 9e-09
Identities = 29/75 (38%), Positives = 43/75 (57%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TA++ +AGL++SL+I GK I+ GAG AS+GI L + +M+
Sbjct: 324 IQGTASIVLAGLVSSLKIAGKNFEDQRILICGAGSASIGIVNLIIKSMEIKGIPYQSALE 383
Query: 189 XIWMVDSRWLIVKNR 233
W+VDS+ LI +R
Sbjct: 384 KFWLVDSKGLITNSR 398
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 58.8 bits (136), Expect = 2e-08
Identities = 31/75 (41%), Positives = 43/75 (57%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T +VA+AGL++++R+ +KL IVF GAG A++GIA+ V AM
Sbjct: 261 IQGTGSVALAGLVSAMRVKKEKLEDQRIVFLGAGAAAVGIADCIVAAMVHDGLSPEDARK 320
Query: 189 XIWMVDSRWLIVKNR 233
W VDSR L+ R
Sbjct: 321 RFWFVDSRGLVTWKR 335
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 54.8 bits (126), Expect = 3e-07
Identities = 30/77 (38%), Positives = 43/77 (55%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAVA+AG++ +LRIT L +F GAG A GIA+L + AM+
Sbjct: 273 IQGTAAVALAGILGALRITEADLCTQRYLFMGAGSAGFGIADLILRAMEQKGIPREQGLK 332
Query: 189 XIWMVDSRWLIVKNRPE 239
+DSR L+ ++R +
Sbjct: 333 QFRFMDSRGLVTRSRTD 349
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 50.0 bits (114), Expect = 1e-05
Identities = 26/48 (54%), Positives = 33/48 (68%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAM 152
IQ TAAV + GL+ RIT K L ++VIVF GAG A++GIA L M +
Sbjct: 302 IQGTAAVGLGGLLGIQRITKKPLEEHVIVFAGAGSAAMGIAYLLKMEL 349
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 50.0 bits (114), Expect = 1e-05
Identities = 27/75 (36%), Positives = 38/75 (50%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AV +AG+I +LR TG + VF GAG A +G+A+ V +
Sbjct: 342 IQGTGAVILAGIINALRRTGVPVKDQRAVFMGAGSAGVGVAQQIVEFFRKEGLTEDEARR 401
Query: 189 XIWMVDSRWLIVKNR 233
W VD++ LI +R
Sbjct: 402 CFWFVDTKGLITNDR 416
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 50.0 bits (114), Expect = 1e-05
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAV V L+A+ + G KLS+ I F GAG A GIAE + M
Sbjct: 268 IQGTAAVTVGSLMAACQAAGSKLSEQRITFLGAGSAGCGIAEAIIAQMVSEGISDKKARS 327
Query: 189 XIWMVDSRW 215
++MVD RW
Sbjct: 328 QVFMVD-RW 335
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/76 (34%), Positives = 39/76 (51%)
Frame = +3
Query: 12 QVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXXX 191
Q AAVA+AG+I R+ S NV +F GA ++G+A LC++ +K
Sbjct: 328 QCFAAVALAGVIVCNRLKRVFFSSNVFLFYGAEAINIGMARLCMVLLKREGLIEMKAREK 387
Query: 192 IWMVDSRWLIVKNRPE 239
IW D+ L+V R +
Sbjct: 388 IWFFDANGLVVLGRKD 403
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/76 (34%), Positives = 38/76 (50%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T A +A I RITG+KL V +F GAG A+LGIA + M ++
Sbjct: 293 IQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATK 352
Query: 189 XIWMVDSRWLIVKNRP 236
I+++D ++ P
Sbjct: 353 NIYLMDVNGILTPESP 368
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 48.8 bits (111), Expect = 2e-05
Identities = 29/71 (40%), Positives = 37/71 (52%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TAAV +AG+ AS RIT K + I+ G G A+ G+AEL + A K
Sbjct: 260 IQGTAAVTLAGIYASCRITHKSFADLKIMLLGTGSAATGVAELLLPAFKAAGLGEAEAHS 319
Query: 189 XIWMVDSRWLI 221
I VD R L+
Sbjct: 320 RISFVDRRGLV 330
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/77 (35%), Positives = 42/77 (54%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ TA+VA+AG+ A+++ TG KL I+F GAG A LGI++L ++
Sbjct: 273 IQGTASVALAGIAAAMKQTGGKLKDQRILFLGAGSAGLGISKLIAAELQTLGLSAEEARK 332
Query: 189 XIWMVDSRWLIVKNRPE 239
+ + D LI +R +
Sbjct: 333 RVRLFDVNGLIESSRTD 349
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 47.6 bits (108), Expect = 5e-05
Identities = 23/75 (30%), Positives = 39/75 (52%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AV +AG I ++ ++ + + +VF GAG A +G+A+ V
Sbjct: 726 IQGTGAVVLAGYIGAVNLSNVPIEEQRLVFMGAGSAGVGVAKQLVEYYTKRGLSEQQAKD 785
Query: 189 XIWMVDSRWLIVKNR 233
W+VD++ L+ K+R
Sbjct: 786 KFWLVDTKGLVTKDR 800
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 46.4 bits (105), Expect = 1e-04
Identities = 27/74 (36%), Positives = 40/74 (54%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AV +A LIA+L+ T + L ++ GAG A LGIA+ V M
Sbjct: 355 IQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARK 414
Query: 189 XIWMVDSRWLIVKN 230
I+++D R LI+++
Sbjct: 415 KIFLMDRRGLILQS 428
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIA-ELCVMAMKXXXXXXXXXX 185
IQ T AVA+A L++++++ G +LS IV GAG A +GIA ++ M
Sbjct: 321 IQGTGAVALAALLSAIKVAGSRLSDQRIVIYGAGSAGMGIADQIKDGLMILEGLNKDEAA 380
Query: 186 XXIWMVDSRWLIVKNRPEG 242
W VD L+V++ G
Sbjct: 381 RRFWCVDRNGLLVESMGNG 399
>UniRef50_Q9HKY7 Cluster: Malate oxidoreductase (Malic enzyme)
related protein; n=17; Archaea|Rep: Malate
oxidoreductase (Malic enzyme) related protein -
Thermoplasma acidophilum
Length = 467
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
TA++ +AG+I SLRI GKK+ Q +VF GAG A++ A L
Sbjct: 191 TASITLAGVINSLRIVGKKIDQVKVVFNGAGAANIAAAYL 230
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 44.4 bits (100), Expect = 5e-04
Identities = 24/75 (32%), Positives = 37/75 (49%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AV +AG++ + RI G+ L V+V GAG G+A M
Sbjct: 291 IQGTGAVVLAGVLNACRIKGEALKDQVVVVHGAGAGGAGVAAAIREGMHREGLSPDEIAR 350
Query: 189 XIWMVDSRWLIVKNR 233
++++DSR L+ +R
Sbjct: 351 RVFVLDSRGLLTDDR 365
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 44.4 bits (100), Expect = 5e-04
Identities = 22/46 (47%), Positives = 29/46 (63%)
Frame = +3
Query: 111 EASLGIAELCVMAMKXXXXXXXXXXXXIWMVDSRWLIVKNRPEGGL 248
+A++GIA L V+AMK IW+VDSR L+VK+R GGL
Sbjct: 242 KAAIGIANLLVLAMKKEGLTEEQAKKKIWLVDSRGLVVKDRDCGGL 287
>UniRef50_A5B3Q7 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 176
Score = 44.0 bits (99), Expect = 6e-04
Identities = 21/48 (43%), Positives = 32/48 (66%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAM 152
IQ T V ++GL+A+L++ G L+ + +F GAGEA GIA+L + M
Sbjct: 129 IQXTTYVVLSGLVAALKLFGGTLANHKFLFLGAGEAENGIAKLMALKM 176
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/77 (29%), Positives = 38/77 (49%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T A +AGLI +LR G I+F GAG +++G++ + +
Sbjct: 263 IQGTGATILAGLINALRAQGTPTKDARIIFFGAGSSAIGVSTQIIQLLMSEGLSEEDARQ 322
Query: 189 XIWMVDSRWLIVKNRPE 239
I+++DS+ LI R +
Sbjct: 323 SIYLMDSKGLITDQRED 339
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 41.9 bits (94), Expect = 0.003
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIA-ELCVMAMKXXXXXXXXXX 185
IQ T A+ VA ++A+++++ LS+ I+ GAG A +GIA +L M+
Sbjct: 263 IQGTGAMVVAAVLATIQVSRIPLSEQKIIIFGAGTAGIGIADQLSAQLMRETGLPFEKAK 322
Query: 186 XXIWMVDSRWLIVKN 230
++VD + L++ N
Sbjct: 323 KHFYLVDRKGLVLDN 337
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 41.9 bits (94), Expect = 0.003
Identities = 24/73 (32%), Positives = 38/73 (52%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AVA+A +I +L +T L++ I+ GAG A +GIA V M
Sbjct: 273 IQGTGAVALAAIIGALHVTKSPLTEQRIMIFGAGTAGVGIANQIVAGMVTDGLSLDKARG 332
Query: 189 XIWMVDSRWLIVK 227
++M+D L+++
Sbjct: 333 NLFMIDRCGLLLE 345
>UniRef50_Q3VJ13 Cluster: Malate dehydrogenase; n=4;
Chlorobium/Pelodictyon group|Rep: Malate dehydrogenase -
Pelodictyon phaeoclathratiforme BU-1
Length = 409
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/44 (43%), Positives = 27/44 (61%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMA 149
TA V +A +I + RITGKK+ ++ GAG A + IA L + A
Sbjct: 172 TAIVTMAAIINACRITGKKIGDLTVIINGAGAAGIAIARLLIHA 215
>UniRef50_A7R628 Cluster: Chromosome undetermined scaffold_1141,
whole genome shotgun sequence; n=3; Vitis vinifera|Rep:
Chromosome undetermined scaffold_1141, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 236
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/48 (41%), Positives = 31/48 (64%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAM 152
IQ T V ++GL+A+L++ G L+ + +F G GEA GIA+L + M
Sbjct: 178 IQGTTYVVLSGLVAALKLFGGTLANHKFLFLGVGEAENGIAKLMALEM 225
>UniRef50_Q5Y0M3 Cluster: Malate oxidoreductase; n=8; cellular
organisms|Rep: Malate oxidoreductase - uncultured
archaeon GZfos12E1
Length = 444
Score = 41.1 bits (92), Expect = 0.005
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Frame = +3
Query: 12 QVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE-LCVMAMKXXXXXXXXXXX 188
Q TA V +AG I +L++ GK+LS+ I GAG A++ +A+ LC+ K
Sbjct: 179 QGTALVILAGAINALKVVGKRLSEIAISLVGAGAANMNVAKYLCLAGAK---------EG 229
Query: 189 XIWMVDSRWLIVKNRPE 239
I MVDS+ ++ + R E
Sbjct: 230 NIVMVDSKGILNRERME 246
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 40.7 bits (91), Expect = 0.006
Identities = 21/41 (51%), Positives = 24/41 (58%)
Frame = +3
Query: 111 EASLGIAELCVMAMKXXXXXXXXXXXXIWMVDSRWLIVKNR 233
+A+LGIA L +MAM IWMVDSR LIVK R
Sbjct: 400 QAALGIAHLLIMAMAKEGLSKEEAARRIWMVDSRGLIVKGR 440
>UniRef50_A5AG28 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 266
Score = 40.3 bits (90), Expect = 0.008
Identities = 19/48 (39%), Positives = 31/48 (64%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAM 152
+Q T V ++GL+A+L++ L+ + +F GAGEA GIA+L + M
Sbjct: 196 VQGTTYVVLSGLVAALKLFSGTLANHKFLFLGAGEAENGIAKLMALEM 243
>UniRef50_Q8U225 Cluster: Malate oxidoreductase; n=41; cellular
organisms|Rep: Malate oxidoreductase - Pyrococcus
furiosus
Length = 435
Score = 40.3 bits (90), Expect = 0.008
Identities = 18/40 (45%), Positives = 27/40 (67%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
TA V +AGLI +L++ GKK ++ + GAG A + IA+L
Sbjct: 174 TAVVTLAGLINALKLVGKKFNEIKVAISGAGAAGIAIAKL 213
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/77 (28%), Positives = 39/77 (50%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T V +AG++ +L+I+G+KL+ + GAG A +GI + M
Sbjct: 260 IQGTGIVVLAGVLGALKISGQKLTDQTYMSFGAGTAGMGIVKQLHEEMVEQGLSDEEAKK 319
Query: 189 XIWMVDSRWLIVKNRPE 239
++VD + L+ + P+
Sbjct: 320 HFFLVDKQGLLFDDDPD 336
>UniRef50_Q81NN6 Cluster: Malate dehydrogenase, putative; n=7;
cellular organisms|Rep: Malate dehydrogenase, putative -
Bacillus anthracis
Length = 414
Score = 39.9 bits (89), Expect = 0.011
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
TA V +AGLI +L++T KK+ IV GAG A + I +L
Sbjct: 164 TAIVTIAGLINALKLTNKKIEDVQIVVNGAGAAGIAIVKL 203
>UniRef50_Q2KKD0 Cluster: Oxalacetate decarboxylase; n=11;
Lactobacillales|Rep: Oxalacetate decarboxylase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 390
Score = 39.9 bits (89), Expect = 0.011
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMA 149
TA V +AGLI + +I GK L++ +V G G + + A+LC+ A
Sbjct: 161 TAIVVLAGLINAAKIKGKPLNELRVVINGVGASGVATAKLCIQA 204
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 39.9 bits (89), Expect = 0.011
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIA-ELCVMAMKXXXXXXXXXX 185
IQ T AV +AG + ++ + G + I+F GAG A++ +A +L +
Sbjct: 363 IQGTGAVILAGFMNAINLAGIPAKDHKILFFGAGSAAVCVAKQLAAYFVNDHGMTEDEAR 422
Query: 186 XXIWMVDSRWLIVKNR 233
+W+VDS+ L+ +R
Sbjct: 423 EMVWLVDSKGLVTLDR 438
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 39.9 bits (89), Expect = 0.011
Identities = 17/42 (40%), Positives = 28/42 (66%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE 134
IQ T A+ +AG++A+++ TG + +V GAG A +GIA+
Sbjct: 291 IQGTGAITLAGVLAAMKKTGASIKDQRVVIFGAGSAGIGIAD 332
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 39.5 bits (88), Expect = 0.014
Identities = 17/75 (22%), Positives = 38/75 (50%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
+Q T A+ + +++++++ KL+ V + GAG +GI E +A+
Sbjct: 279 VQGTGAITFSAILSAMKVKRAKLTDQVFLIHGAGAGGVGIGEQIQVALMAEGLSEEEARD 338
Query: 189 XIWMVDSRWLIVKNR 233
++ +DSR ++ +R
Sbjct: 339 KVFTIDSRGVVTVDR 353
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 39.1 bits (87), Expect = 0.018
Identities = 20/75 (26%), Positives = 36/75 (48%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
+Q T AV +AG+I S ++ G+ L GAG +G+A+ +
Sbjct: 278 VQGTGAVVLAGIIGSTKMKGETLIDQTYAVYGAGAGGVGVADQIFAGLLKEGLSHQEARD 337
Query: 189 XIWMVDSRWLIVKNR 233
I+++DSR ++ +R
Sbjct: 338 RIFILDSRGVVFADR 352
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 38.7 bits (86), Expect = 0.024
Identities = 24/75 (32%), Positives = 34/75 (45%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AV AG +++++ L Q IVF GAG A+ G+AE
Sbjct: 273 IQGTGAVIAAGFHTAVKLSKIPLEQQRIVFFGAGSAATGVAESIADLAAETGVKKEGIKK 332
Query: 189 XIWMVDSRWLIVKNR 233
+ VDS ++ NR
Sbjct: 333 NTFFVDSMGMVATNR 347
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 38.7 bits (86), Expect = 0.024
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLR----ITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXX 176
I+ T +V +AG +A+ + +GK L + +VF G G A++G+A+ +
Sbjct: 308 IEGTGSVILAGFLAAAKHASEASGKPLRDHKVVFLGGGSAAVGVAKEMMNFFMMQGLTED 367
Query: 177 XXXXXIWMVDSRWLIVKNRPE 239
W++D++ LI R +
Sbjct: 368 EARERFWLIDTKGLITSTRAD 388
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 38.7 bits (86), Expect = 0.024
Identities = 21/75 (28%), Positives = 38/75 (50%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T AV + G+I +++ +G ++ VF GAG A +G+A+ V
Sbjct: 334 IQGTGAVILGGVINAVKRSGLPCKEHRAVFLGAGSAGVGVAKQIVAFFMREGMTEDEARS 393
Query: 189 XIWMVDSRWLIVKNR 233
++VD++ L+ +R
Sbjct: 394 CFYLVDTKGLVTADR 408
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 38.3 bits (85), Expect = 0.032
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Frame = +3
Query: 75 LSQNVIVFQGAGEASLGIAELCVMAM-KXXXXXXXXXXXXIWMVDSRWLIVKNRPE 239
L++ +F GAGEA GIAEL + + K IW+V+S+ LIV +R E
Sbjct: 452 LAELTFLFLGAGEAGTGIAELIALEISKQTKAPLEETRKKIWLVNSKGLIVHSRME 507
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 37.9 bits (84), Expect = 0.043
Identities = 18/41 (43%), Positives = 28/41 (68%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIA 131
IQ T AV +AG+I ++R TG ++ + +F GAG A+ G+A
Sbjct: 288 IQGTGAVILAGVINAVRATGVPVADHRFMFLGAGSAATGVA 328
>UniRef50_Q9YF49 Cluster: Malate dehydrogenase; n=3; Archaea|Rep:
Malate dehydrogenase - Aeropyrum pernix
Length = 446
Score = 37.9 bits (84), Expect = 0.043
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = +3
Query: 12 QVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGI 128
Q TAA ++AGLI + +I GK L ++ IV GAG A++ +
Sbjct: 169 QGTAAASLAGLINAFKIVGKNLRESRIVLLGAGAANIAL 207
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 37.5 bits (83), Expect = 0.056
Identities = 25/76 (32%), Positives = 34/76 (44%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXX 188
IQ T VA A + A+ G L + IV GAG A GIAE V +
Sbjct: 223 IQGTRGVACAVVKAASHGAGLPLEDHRIVVFGAGTAGCGIAEGLVRLLTRAGLSEPEARR 282
Query: 189 XIWMVDSRWLIVKNRP 236
IW +D L++ ++P
Sbjct: 283 RIWAIDREGLVLADQP 298
>UniRef50_Q27113 Cluster: Malic enzyme; n=1; Trichomonas
vaginalis|Rep: Malic enzyme - Trichomonas vaginalis
Length = 434
Score = 37.1 bits (82), Expect = 0.074
Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITG-KKLSQNVIVFQGAGEASLGIAELCV-MAMKXXXXXXXXX 182
I+ TAAVA A L ++ + G L I+F GAG A++GIA L V M +
Sbjct: 155 IEGTAAVAAATLASATHMEGVPDLKNQKIIFIGAGSAAIGIANLIVDMTVSRGGITKEQA 214
Query: 183 XXXIWMVDSRWLIVKNRPE 239
I M D R ++ R +
Sbjct: 215 FKNIIMFDHRGMVHAGRKD 233
>UniRef50_Q73JN6 Cluster: Malate dehydrogenase; n=3; cellular
organisms|Rep: Malate dehydrogenase - Treponema
denticola
Length = 491
Score = 36.7 bits (81), Expect = 0.098
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +3
Query: 12 QVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
Q TA + +AGL+ ++++ GKK+ IV GAG ++ IA L
Sbjct: 199 QGTACITLAGLLNAIKLAGKKMEDCKIVLLGAGASNTTIARL 240
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 36.7 bits (81), Expect = 0.098
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIA-ELCVMAMKXXXXXXXXXX 185
IQ T AV +A + A++ +T L IV G+G A LGIA +L
Sbjct: 280 IQGTGAVTLAAVQAAISVTKSSLKDQRIVIYGSGSAGLGIARQLRDAIALDSSGSPSEAA 339
Query: 186 XXIWMVDSRWLIVKN 230
W++D LI K+
Sbjct: 340 KQFWLIDKHGLIKKS 354
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 35.9 bits (79), Expect = 0.17
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITG-KKLSQNVIVFQGAGEASLGIAELCV-MAMKXXXXXXXXX 182
I+ TAAVA A L ++ + G L I+F GAG A+ GIA L V M +
Sbjct: 280 IEGTAAVAAATLASATHMEGVPDLKNQKIIFIGAGSAATGIANLIVDMTVSRGGITKEQA 339
Query: 183 XXXIWMVDSRWLIVKNRPE 239
I M D R ++ R +
Sbjct: 340 FKNIIMFDHRGMVHAGRKD 358
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 35.5 bits (78), Expect = 0.23
Identities = 19/43 (44%), Positives = 26/43 (60%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
IQ TAAVA A ++A L+ G L+ ++ GAG A GIA +
Sbjct: 248 IQGTAAVASACVLAGLQQAGTTLADTPVLIVGAGSAGCGIAAM 290
>UniRef50_A4M6V5 Cluster: Malate dehydrogenase; n=2;
Thermotogaceae|Rep: Malate dehydrogenase - Petrotoga
mobilis SJ95
Length = 379
Score = 35.5 bits (78), Expect = 0.23
Identities = 17/41 (41%), Positives = 24/41 (58%)
Frame = +3
Query: 12 QVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE 134
Q TA V AGL+ +L++TGK+ +V G G A IA+
Sbjct: 157 QGTAVVVTAGLLNALKLTGKEAKNIKVVINGIGAAGYNIAK 197
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 35.5 bits (78), Expect = 0.23
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITG---KKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXX 179
IQ TAAV +AGL +++ G K + + V GAG A GIA A+
Sbjct: 334 IQGTAAVVLAGLYGAMKCLGGHRKDIVKQTFVMCGAGSAGSGIASFIHQALVANGLSEDE 393
Query: 180 XXXXIWMVDSRWLIVKNR 233
+++D LI +R
Sbjct: 394 AYQRFYIIDKDGLITHDR 411
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 35.5 bits (78), Expect = 0.23
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE 134
+Q T V +A ++A L I+ +KLS +V GAG A +GIA+
Sbjct: 290 VQGTGCVTLAAIMAGLHISKQKLSDVRMVVFGAGTAGVGIAD 331
>UniRef50_A0K0I7 Cluster: Malate dehydrogenase; n=87; cellular
organisms|Rep: Malate dehydrogenase - Arthrobacter sp.
(strain FB24)
Length = 479
Score = 35.1 bits (77), Expect = 0.30
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
TA V +A L+ +LR+ KKLS+ IV G G A I +L
Sbjct: 240 TAIVTLAALVNALRVVDKKLSEVRIVVSGVGAAGSAIIQL 279
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 35.1 bits (77), Expect = 0.30
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 3/45 (6%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITG---KKLSQNVIVFQGAGEASLGIAE 134
IQ T+++ +AG++ASL+ G + LS I+ GAG A +G+ E
Sbjct: 304 IQSTSSITLAGILASLKSRGMSQEDLSNERIICVGAGSAGVGVCE 348
>UniRef50_O30808 Cluster: NADP-dependent malic enzyme; n=132;
cellular organisms|Rep: NADP-dependent malic enzyme -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 761
Score = 35.1 bits (77), Expect = 0.30
Identities = 24/75 (32%), Positives = 38/75 (50%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMAMKXXXXXXXXXXXXIW 197
TA +A AGL+ +L +TG+ +V GAG A++ EL + AM I
Sbjct: 176 TAIIAAAGLVNALTLTGRDFKTAKLVCNGAGAAAIACIEL-IKAM-------GFNPENII 227
Query: 198 MVDSRWLIVKNRPEG 242
+ D++ +I K R +G
Sbjct: 228 LCDTKGVIYKGRTDG 242
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 34.7 bits (76), Expect = 0.40
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE-LCVMAMKXXXXXXXXXX 185
IQ T V +A L++ + G +L +V G+G A GIAE L
Sbjct: 312 IQGTGCVTLAALLSGFHVGGIELEDARVVVFGSGSAGTGIAEQLADTIATETHKPKEEAS 371
Query: 186 XXIWMVDSRWLIVKN 230
IW +D L+VK+
Sbjct: 372 KQIWCLDKPGLLVKS 386
>UniRef50_A7DL10 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+))., Phosphate
acetyltransferase; n=2; Methylobacterium extorquens
PA1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+))., Phosphate
acetyltransferase - Methylobacterium extorquens PA1
Length = 932
Score = 34.3 bits (75), Expect = 0.52
Identities = 17/42 (40%), Positives = 24/42 (57%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCV 143
TA + A ++ +L + GK+LS IV GAG A+L L V
Sbjct: 325 TAIIVAAAVLNALELAGKRLSDAKIVTSGAGAAALACLNLLV 366
>UniRef50_Q7MXC5 Cluster: NADP-dependent malic enzyme; n=1;
Porphyromonas gingivalis|Rep: NADP-dependent malic
enzyme - Porphyromonas gingivalis (Bacteroides
gingivalis)
Length = 759
Score = 33.9 bits (74), Expect = 0.69
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
TA ++ AGLI +L I GKK+ IV GAG ++ +L
Sbjct: 166 TAIISSAGLINALMIAGKKIEDVRIVVNGAGASAFSCTKL 205
>UniRef50_P16468 Cluster: NAD-dependent malic enzyme; n=32;
Bacteria|Rep: NAD-dependent malic enzyme - Bacillus
stearothermophilus (Geobacillus stearothermophilus)
Length = 478
Score = 33.5 bits (73), Expect = 0.92
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMA 149
TA V +AGL+ +L+I KKL +V G G A + ++ + A
Sbjct: 241 TAVVLLAGLLNALKIVDKKLEDIKVVLTGIGAAGIACTKILLAA 284
>UniRef50_A6H1G1 Cluster: Malate dehydrogenase; n=3; Bacteria|Rep:
Malate dehydrogenase - Flavobacterium psychrophilum
(strain JIP02/86 / ATCC 49511)
Length = 771
Score = 33.1 bits (72), Expect = 1.2
Identities = 16/43 (37%), Positives = 25/43 (58%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVM 146
TA ++ A L+ +L + KK+ +V GAG A+L A L V+
Sbjct: 167 TAIISSAALLNALELANKKIETVKLVVSGAGSAALACANLYVL 209
>UniRef50_A1GDI9 Cluster: Putative uncharacterized protein; n=1;
Salinispora arenicola CNS205|Rep: Putative
uncharacterized protein - Salinispora arenicola CNS205
Length = 358
Score = 31.9 bits (69), Expect = 2.8
Identities = 15/31 (48%), Positives = 16/31 (51%)
Frame = -2
Query: 215 PSRVHHPDAAARLRLRRTPGLHRHHAQLRYT 123
P R HHP R R RR HRH Q R+T
Sbjct: 256 PPRRHHPHRRRRPRRRRQHRRHRHRHQRRHT 286
>UniRef50_A6PP44 Cluster: Putative uncharacterized protein; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Putative
uncharacterized protein - Victivallis vadensis ATCC
BAA-548
Length = 415
Score = 31.5 bits (68), Expect = 3.7
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +3
Query: 6 RIQVTAAVAVAGLIASLRITGKKLSQNVIVFQ 101
R +V A +A AGLIA+L +TG + V+V +
Sbjct: 43 RPKVVAGIAAAGLIAALALTGSRTGMAVLVME 74
>UniRef50_Q7VH73 Cluster: Malate oxidoreductase; n=1; Helicobacter
hepaticus|Rep: Malate oxidoreductase - Helicobacter
hepaticus
Length = 404
Score = 31.1 bits (67), Expect = 4.9
Identities = 14/40 (35%), Positives = 24/40 (60%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAEL 137
TA ++ AG+I +L + KK +V GAG A++ A++
Sbjct: 167 TAIISTAGIINALHLVNKKAKDIKVVVFGAGAAAVACAKM 206
>UniRef50_Q3W7J3 Cluster: Malate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Malate dehydrogenase - Frankia sp. EAN1pec
Length = 464
Score = 31.1 bits (67), Expect = 4.9
Identities = 16/44 (36%), Positives = 24/44 (54%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAELCVMA 149
TA VA+A L + R+TG+ L V GAG A + + + + A
Sbjct: 240 TAIVALAALENAARLTGRTLGDLRAVVSGAGAAGVAVTRILLAA 283
>UniRef50_Q3JAT5 Cluster: Malate dehydrogenase; n=1; Nitrosococcus
oceani ATCC 19707|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 783
Score = 30.7 bits (66), Expect = 6.5
Identities = 14/39 (35%), Positives = 23/39 (58%)
Frame = +3
Query: 18 TAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE 134
TA ++ A L+ + + GK+L +V GAG AS+ A+
Sbjct: 164 TAIISGAALLNACELAGKRLEDIKLVMNGAGAASIACAK 202
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 30.7 bits (66), Expect = 6.5
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +3
Query: 9 IQVTAAVAVAGLIASLRITGKKLSQNVIVFQGAGEASLGIAE 134
+Q T V +A + A L ++ KL +V G G A +GIA+
Sbjct: 266 VQGTGCVTLAAIFAGLHVSKTKLGDLRMVVFGGGTAGVGIAD 307
>UniRef50_A5NQD6 Cluster: Cobalamin B12-binding domain protein; n=1;
Methylobacterium sp. 4-46|Rep: Cobalamin B12-binding
domain protein - Methylobacterium sp. 4-46
Length = 288
Score = 30.3 bits (65), Expect = 8.5
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Frame = -2
Query: 236 GPVLHDQPSRVHHPDAAARL-RLRRTPGLHRHHAQLR 129
GP HD+P RV H A A + R PG+ + LR
Sbjct: 248 GPAFHDRPDRVRHAGADAAVGDARNAPGIAQSLLDLR 284
>UniRef50_A7RUG2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 56
Score = 30.3 bits (65), Expect = 8.5
Identities = 13/27 (48%), Positives = 15/27 (55%)
Frame = -2
Query: 203 HHPDAAARLRLRRTPGLHRHHAQLRYT 123
H+PD AAR L R GL Q+ YT
Sbjct: 23 HYPDVAARSELSRRTGLSESQVQVSYT 49
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 188,005,811
Number of Sequences: 1657284
Number of extensions: 2463895
Number of successful extensions: 8145
Number of sequences better than 10.0: 76
Number of HSP's better than 10.0 without gapping: 8000
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8137
length of database: 575,637,011
effective HSP length: 61
effective length of database: 474,542,687
effective search space used: 9965396427
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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