BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= S06A01NCLL0002_E20 (511 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 186 2e-46 UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 134 1e-30 UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 130 2e-29 UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 129 3e-29 UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 121 8e-27 UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 121 1e-26 UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 120 3e-26 UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 118 6e-26 UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 117 1e-25 UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 116 3e-25 UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 116 3e-25 UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 115 5e-25 UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 115 7e-25 UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 115 7e-25 UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 115 7e-25 UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 114 1e-24 UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 113 2e-24 UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 113 2e-24 UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 113 3e-24 UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 112 4e-24 UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 112 4e-24 UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 112 4e-24 UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 112 5e-24 UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 111 7e-24 UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 111 7e-24 UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 111 7e-24 UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 111 7e-24 UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 111 9e-24 UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 111 1e-23 UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 110 2e-23 UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 109 3e-23 UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 109 4e-23 UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 109 4e-23 UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 109 4e-23 UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 109 4e-23 UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 109 5e-23 UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 107 1e-22 UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 107 1e-22 UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 107 1e-22 UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 106 3e-22 UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 105 6e-22 UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 105 6e-22 UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 105 8e-22 UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 104 1e-21 UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 104 1e-21 UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 104 1e-21 UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 103 2e-21 UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 103 2e-21 UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 103 3e-21 UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 103 3e-21 UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 103 3e-21 UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 103 3e-21 UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 102 4e-21 UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 102 4e-21 UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 102 4e-21 UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 102 5e-21 UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 102 5e-21 UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 101 7e-21 UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 101 7e-21 UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 101 7e-21 UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 101 7e-21 UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 101 9e-21 UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 101 9e-21 UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 101 1e-20 UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 100 2e-20 UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 100 2e-20 UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 100 2e-20 UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 99 2e-20 UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 100 2e-20 UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 100 2e-20 UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 100 2e-20 UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 100 2e-20 UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 99 3e-20 UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 99 3e-20 UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 100 4e-20 UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 99 5e-20 UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 99 5e-20 UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 99 5e-20 UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 99 7e-20 UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 98 9e-20 UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 98 9e-20 UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 98 1e-19 UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 97 2e-19 UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 97 2e-19 UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 97 2e-19 UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 97 2e-19 UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 97 2e-19 UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 97 3e-19 UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 97 3e-19 UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 94 3e-19 UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 94 3e-19 UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 96 4e-19 UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 96 4e-19 UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 96 5e-19 UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 95 6e-19 UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 95 6e-19 UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 95 8e-19 UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 95 1e-18 UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 95 1e-18 UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 94 1e-18 UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 94 1e-18 UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 94 1e-18 UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 94 2e-18 UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 94 2e-18 UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 94 2e-18 UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 94 2e-18 UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 93 3e-18 UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 93 3e-18 UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 3e-18 UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 93 3e-18 UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 93 3e-18 UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 93 4e-18 UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 92 8e-18 UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 92 8e-18 UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 91 1e-17 UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 91 1e-17 UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 91 1e-17 UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 91 1e-17 UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 91 1e-17 UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 91 1e-17 UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 91 2e-17 UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 90 2e-17 UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 90 2e-17 UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 90 2e-17 UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 90 2e-17 UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 90 2e-17 UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 89 4e-17 UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 89 5e-17 UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 89 7e-17 UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 88 9e-17 UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 88 9e-17 UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 88 1e-16 UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 88 1e-16 UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 87 2e-16 UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 87 2e-16 UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-16 UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 87 2e-16 UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 87 2e-16 UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 87 3e-16 UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 87 3e-16 UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 86 5e-16 UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 86 5e-16 UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 86 5e-16 UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 86 5e-16 UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 85 7e-16 UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 85 7e-16 UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 85 7e-16 UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 85 7e-16 UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 85 9e-16 UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 85 1e-15 UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 85 1e-15 UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 85 1e-15 UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 85 1e-15 UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 85 1e-15 UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 84 2e-15 UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 84 2e-15 UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 84 2e-15 UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 84 2e-15 UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 83 3e-15 UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 83 4e-15 UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 83 5e-15 UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 83 5e-15 UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 83 5e-15 UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 82 6e-15 UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 82 6e-15 UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 82 6e-15 UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 82 8e-15 UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 82 8e-15 UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 82 8e-15 UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 81 1e-14 UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 1e-14 UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 81 1e-14 UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-14 UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 81 1e-14 UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 81 1e-14 UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 1e-14 UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 81 1e-14 UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 81 1e-14 UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 81 2e-14 UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 81 2e-14 UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 81 2e-14 UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 80 3e-14 UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 80 3e-14 UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 80 3e-14 UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 80 3e-14 UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 80 3e-14 UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 79 4e-14 UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 79 4e-14 UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 79 6e-14 UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 79 8e-14 UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 79 8e-14 UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 79 8e-14 UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 78 1e-13 UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13 UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 78 1e-13 UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 78 1e-13 UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 78 1e-13 UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 78 1e-13 UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13 UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 78 1e-13 UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13 UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 77 2e-13 UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 77 2e-13 UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 77 2e-13 UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 77 2e-13 UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 77 2e-13 UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 77 3e-13 UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 76 4e-13 UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 76 5e-13 UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 7e-13 UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 75 7e-13 UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 75 7e-13 UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 75 7e-13 UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 75 9e-13 UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 75 9e-13 UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 74 2e-12 UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 74 2e-12 UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 74 2e-12 UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 74 2e-12 UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 73 3e-12 UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 73 3e-12 UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 73 4e-12 UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 73 4e-12 UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 73 5e-12 UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 73 5e-12 UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 73 5e-12 UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 73 5e-12 UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 72 7e-12 UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 72 7e-12 UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 72 9e-12 UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 71 1e-11 UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 71 1e-11 UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 71 1e-11 UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 71 1e-11 UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 71 2e-11 UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 70 3e-11 UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 70 4e-11 UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 70 4e-11 UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 70 4e-11 UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 69 5e-11 UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 69 5e-11 UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 69 6e-11 UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 69 6e-11 UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 69 8e-11 UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 69 8e-11 UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 69 8e-11 UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 69 8e-11 UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 69 8e-11 UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 68 1e-10 UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 68 1e-10 UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 68 1e-10 UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 68 1e-10 UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 68 1e-10 UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 67 2e-10 UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 67 2e-10 UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 67 2e-10 UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 66 3e-10 UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 66 3e-10 UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 66 4e-10 UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 66 6e-10 UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 66 6e-10 UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10 UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 65 1e-09 UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 65 1e-09 UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 64 1e-09 UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 64 1e-09 UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-09 UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09 UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 64 2e-09 UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 64 2e-09 UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 63 3e-09 UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 63 3e-09 UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 63 4e-09 UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 62 5e-09 UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 62 7e-09 UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 62 9e-09 UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 61 1e-08 UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 61 2e-08 UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08 UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 61 2e-08 UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 61 2e-08 UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 61 2e-08 UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 60 2e-08 UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 60 2e-08 UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 60 3e-08 UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 60 3e-08 UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 60 3e-08 UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 60 4e-08 UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 59 5e-08 UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 59 7e-08 UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 59 7e-08 UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 58 2e-07 UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 57 2e-07 UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 2e-07 UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 57 3e-07 UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 57 3e-07 UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 57 3e-07 UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07 UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 56 4e-07 UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 56 4e-07 UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 55 8e-07 UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 55 8e-07 UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 55 8e-07 UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 1e-06 UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 54 1e-06 UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 54 2e-06 UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 54 2e-06 UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 54 2e-06 UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 53 3e-06 UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 53 3e-06 UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 52 6e-06 UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 52 6e-06 UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 52 6e-06 UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 52 6e-06 UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 52 6e-06 UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 52 8e-06 UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 52 8e-06 UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 52 8e-06 UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 52 1e-05 UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 51 1e-05 UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 51 1e-05 UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 51 1e-05 UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 51 2e-05 UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 50 2e-05 UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 50 2e-05 UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 50 2e-05 UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 50 3e-05 UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 50 3e-05 UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 50 3e-05 UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 50 3e-05 UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 50 4e-05 UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 50 4e-05 UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 50 4e-05 UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 50 4e-05 UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 50 4e-05 UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 50 4e-05 UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta... 49 5e-05 UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 49 5e-05 UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 49 5e-05 UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 49 7e-05 UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 49 7e-05 UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-05 UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 48 9e-05 UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 48 9e-05 UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 48 1e-04 UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 48 1e-04 UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 48 1e-04 UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 48 1e-04 UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 48 1e-04 UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 48 2e-04 UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 48 2e-04 UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141, w... 48 2e-04 UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 48 2e-04 UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 47 2e-04 UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 47 2e-04 UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 47 2e-04 UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 47 2e-04 UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 47 2e-04 UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep... 47 3e-04 UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 47 3e-04 UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 46 4e-04 UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 46 4e-04 UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 46 4e-04 UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 46 4e-04 UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 46 4e-04 UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 46 4e-04 UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 46 5e-04 UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 46 5e-04 UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 5e-04 UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 46 5e-04 UniRef50_A7DBQ3 Cluster: Aldo/keto reductase precursor; n=2; Met... 46 5e-04 UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 46 5e-04 UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 46 5e-04 UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 46 5e-04 UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 7e-04 UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 46 7e-04 UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 46 7e-04 UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 46 7e-04 UniRef50_A7AFU4 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04 UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 46 7e-04 UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 46 7e-04 UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04 UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 46 7e-04 UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 46 7e-04 UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 46 7e-04 UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 45 9e-04 UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 45 9e-04 UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 45 9e-04 UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 45 9e-04 UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 45 9e-04 UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 9e-04 UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 45 9e-04 UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 45 9e-04 UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 45 9e-04 UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 45 0.001 UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 45 0.001 UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac... 45 0.001 UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 45 0.001 UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 45 0.001 UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 45 0.001 UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 44 0.002 UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 44 0.002 UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 44 0.002 UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 44 0.002 UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 44 0.002 UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 44 0.002 UniRef50_Q4TBS9 Cluster: Chromosome undetermined SCAF7094, whole... 44 0.003 UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 44 0.003 UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 44 0.003 UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 44 0.003 UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003 UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 43 0.004 UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 43 0.004 UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 43 0.004 UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 43 0.004 UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 43 0.004 UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 43 0.004 UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 43 0.004 UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 43 0.004 UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 43 0.004 UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 43 0.004 UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 43 0.004 UniRef50_A7E982 Cluster: Putative uncharacterized protein; n=1; ... 43 0.004 UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 43 0.004 UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 43 0.005 UniRef50_UPI000023CA3A Cluster: hypothetical protein FG01742.1; ... 43 0.005 UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 43 0.005 UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 43 0.005 UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 43 0.005 UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga... 43 0.005 UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 43 0.005 UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 42 0.006 UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 42 0.006 UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 42 0.006 UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 42 0.006 UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 42 0.006 UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 42 0.006 UniRef50_Q9X123 Cluster: Oxidoreductase, putative; n=4; Bacteria... 42 0.008 UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 42 0.008 UniRef50_Q1H0C2 Cluster: Twin-arginine translocation pathway sig... 42 0.008 UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 42 0.008 UniRef50_A5UT57 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 42 0.008 UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 42 0.008 UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 42 0.011 UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 42 0.011 UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 42 0.011 UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 42 0.011 UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1... 42 0.011 UniRef50_Q5AQH3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011 UniRef50_Q1PBI2 Cluster: L-galactose dehydrogenase; n=15; Magnol... 41 0.014 UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.014 UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 41 0.014 UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 41 0.014 UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 41 0.019 UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 41 0.019 UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 41 0.019 UniRef50_A0JTR5 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 41 0.019 UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 41 0.019 UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 41 0.019 UniRef50_Q2H7K8 Cluster: Putative uncharacterized protein; n=1; ... 41 0.019 UniRef50_Q7UL88 Cluster: DTDP-4-keto-L-6-deoxy-hexose 2,3-reduct... 40 0.025 UniRef50_Q6A7U3 Cluster: Putative oxidoreductase; n=1; Propionib... 40 0.025 UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 40 0.025 UniRef50_Q0LSA5 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 40 0.025 UniRef50_Q4WE64 Cluster: Aldo-keto reductase (AKR), putative; n=... 40 0.025 UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 40 0.025 UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 40 0.033 UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.033 UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 40 0.033 UniRef50_Q0AQX2 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 40 0.033 UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 40 0.033 UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.033 UniRef50_A1SEE9 Cluster: Aldo/keto reductase; n=1; Nocardioides ... 40 0.033 UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.033 UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 40 0.033 UniRef50_Q9HNN3 Cluster: General stress protein 69; n=5; Halobac... 40 0.033 UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 40 0.043 UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 40 0.043 UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 40 0.043 UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 40 0.043 UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3; Actinomyc... 40 0.043 UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 40 0.043 UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 40 0.043 UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 40 0.043 UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 40 0.043 UniRef50_A6RNJ6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.043 UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 40 0.043 UniRef50_Q8DHB7 Cluster: Tlr2042 protein; n=16; Cyanobacteria|Re... 39 0.057 UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 39 0.057 UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 39 0.057 UniRef50_A0L4P0 Cluster: Aldo/keto reductase; n=1; Magnetococcus... 39 0.057 UniRef50_Q295T6 Cluster: GA14985-PA; n=1; Drosophila pseudoobscu... 39 0.057 UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.057 UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 39 0.057 UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 39 0.076 UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.076 UniRef50_Q2NSC7 Cluster: Putative oxidoreductase; n=1; Sodalis g... 39 0.076 >UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase - Trichoplusia ni (Cabbage looper) Length = 308 Score = 186 bits (454), Expect = 2e-46 Identities = 92/141 (65%), Positives = 109/141 (77%), Gaps = 1/141 (0%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGT-GRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 +AP QLNDG IP LALGT G G + +VRQAV WAI+AGYRHIDTAA+YG+EE Sbjct: 23 KAPLKQLNDGNAIPSLALGTFGFGD------IPKVRQAVLWAIQAGYRHIDTAALYGNEE 76 Query: 269 QVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 +VG+GIA+AI +GLV RE+LF+TTKLWNDKH R QVVP LRESL +LGL YVDLYLIH P Sbjct: 77 EVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSP 136 Query: 449 ISSKADGSPDNIDYLETWEGM 511 ++ +G P +ID L TW GM Sbjct: 137 EATNENGDPVDIDVLNTWNGM 157 >UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precursor; n=1; Spodoptera littoralis|Rep: 3-dehydroecdysone 3beta-reductase precursor - Spodoptera littoralis (Egyptian cotton leafworm) Length = 345 Score = 134 bits (323), Expect = 1e-30 Identities = 66/144 (45%), Positives = 92/144 (63%), Gaps = 4/144 (2%) Frame = +2 Query: 83 STAQAPCHQLNDGYKIPVLALGT----GRGTASESDTLDQVRQAVFWAIEAGYRHIDTAA 250 +T P ++ + ++P +ALGT +G A S Q+R V AI+ GYRH DTAA Sbjct: 18 ATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKD-KQLRNVVMQAIDLGYRHFDTAA 76 Query: 251 VYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDL 430 +Y E +VG+ I I +G++ RED+F+TTKLWN H R QV ++E+L + GLDYVDL Sbjct: 77 IYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDL 136 Query: 431 YLIHFPISSKADGSPDNIDYLETW 502 +L+H+PI+ D S N DYLETW Sbjct: 137 FLMHWPIALNEDYSHSNTDYLETW 160 >UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 321 Score = 130 bits (313), Expect = 2e-29 Identities = 66/145 (45%), Positives = 93/145 (64%), Gaps = 11/145 (7%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+DG K+PVL LGT +G + D+V AV AI+AGYRH D A+ YG+E ++G+ I Sbjct: 10 LSDGNKVPVLGLGTWQG----GNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQ 65 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS----- 454 E I +G+V REDLF+ TK+WND+ + VV + SL++LGL Y+DLYL+H+P S Sbjct: 66 EKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILY 125 Query: 455 ------SKADGSPDNIDYLETWEGM 511 + + D +DY+ETW GM Sbjct: 126 QYIVLPTYNAVTLDEVDYIETWRGM 150 >UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to GA10458-PA - Nasonia vitripennis Length = 569 Score = 129 bits (312), Expect = 3e-29 Identities = 65/149 (43%), Positives = 92/149 (61%), Gaps = 11/149 (7%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P NDGYK+P++ LGT E V +AV +AIE GYRH+DTA Y +E+++G Sbjct: 4 PTVTFNDGYKMPMIGLGTFLSKPGE------VAEAVKYAIEVGYRHVDTAFFYENEKEIG 57 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 I E I G + RED+F+TTKLW + H +VVP ++SL+ LG DY+DL+L+H+P + Sbjct: 58 SAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAF 117 Query: 458 KADG--SP---------DNIDYLETWEGM 511 K+ +P + DYLETW+GM Sbjct: 118 KSGDALTPRDAAGKIEFSDTDYLETWKGM 146 Score = 103 bits (247), Expect = 2e-21 Identities = 53/103 (51%), Positives = 66/103 (64%), Gaps = 8/103 (7%) Frame = +2 Query: 227 YRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQR 406 YRHIDTA +Y +E+ +G I E I G V REDLF+TTKL H +VVP ++SL Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360 Query: 407 LGLDYVDLYLIHFPI------SSKADGS--PDNIDYLETWEGM 511 LGLDY+DLYLIH+PI + A G + DYLETW+GM Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGM 403 >UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: Aldehyde reductase - gamma proteobacterium HTCC2207 Length = 330 Score = 121 bits (292), Expect = 8e-27 Identities = 55/92 (59%), Positives = 70/92 (76%) Frame = +2 Query: 179 TLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDK 358 T D QAV+ AI+ GYRH+D+AA YG+E+QVG+GIA AIA+GL +RE+L+ITTKLWN Sbjct: 28 TQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIARAIAEGLCSREELWITTKLWNTY 87 Query: 359 HARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 H V R S+ LGLDY+DLYL+HFPI+ Sbjct: 88 HRAEHVEAACRRSMDDLGLDYIDLYLVHFPIA 119 >UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase family; n=2; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 305 Score = 121 bits (291), Expect = 1e-26 Identities = 70/138 (50%), Positives = 90/138 (65%), Gaps = 4/138 (2%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+GYKIP L LGT E V +AV AI+ GYRHID A YG+E++VG GI Sbjct: 7 LNNGYKIPKLGLGTWMSANGE------VGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIK 60 Query: 290 EAIAKGLVTREDLFITTKLWN-DKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS-KA 463 AIAKG V RE+LF+TTKLW+ DKH + V P ESL++L L+Y+DLY+IH P+++ K Sbjct: 61 SAIAKGYVKREELFVTTKLWSTDKH-KEDVRPACLESLKKLQLEYLDLYIIHIPLTADKK 119 Query: 464 DG--SPDNIDYLETWEGM 511 G + + I ETW M Sbjct: 120 TGEFTEEIIPIEETWREM 137 >UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep: GCY protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 295 Score = 120 bits (288), Expect = 3e-26 Identities = 63/138 (45%), Positives = 94/138 (68%), Gaps = 2/138 (1%) Frame = +2 Query: 104 HQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQG 283 + LN+G KIP + LGT +D D +A A++ GY+HIDTAA YG+E+QVG+ Sbjct: 12 YTLNNGLKIPAIGLGTWL-----ADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVGRA 66 Query: 284 IAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS--S 457 IA++ G V+R+++F+TTKLWND+H + L ESL++LGL+YVDLYLIH+P+S Sbjct: 67 IADS---G-VSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLSVDP 120 Query: 458 KADGSPDNIDYLETWEGM 511 K + D+ D+++TW + Sbjct: 121 KTEKPYDDYDFVDTWRNL 138 >UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p - Drosophila melanogaster (Fruit fly) Length = 311 Score = 118 bits (285), Expect = 6e-26 Identities = 66/150 (44%), Positives = 90/150 (60%), Gaps = 8/150 (5%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 T AP +LN+G ++P L LGT + + ESD R A ++ GYRH+DTA VY +E Sbjct: 2 TNLAPTIRLNNGREMPTLGLGTWK--SFESDAYHSTRHA----LDVGYRHLDTAFVYENE 55 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 +VGQ I+E IA+G+VTRE++F+TTKL H V R SL LGL+YVDLYL+H Sbjct: 56 AEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHM 115 Query: 446 PISSKADGSPD--------NIDYLETWEGM 511 P+ K + ++DYL+TW M Sbjct: 116 PVGQKFHNDSNVHGTLELTDVDYLDTWREM 145 >UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; Lactobacillus|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri 100-23 Length = 288 Score = 117 bits (282), Expect = 1e-25 Identities = 66/134 (49%), Positives = 80/134 (59%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G KIP + GT R A D QAV AIE GYRHIDTAAVYG+EE VG+GI Sbjct: 13 LNNGVKIPCVGYGTFRTPA------DVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGIK 66 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 ++ K REDLF+T+KLWN Q +E+L RL +DY+DLYLIH+P + K G Sbjct: 67 DSGIK----REDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG 122 Query: 470 SPDNIDYLETWEGM 511 ETW M Sbjct: 123 DDAAKINAETWRAM 136 >UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebacterium jeikeium K411|Rep: Putative oxidoreductase - Corynebacterium jeikeium (strain K411) Length = 285 Score = 116 bits (279), Expect = 3e-25 Identities = 61/117 (52%), Positives = 78/117 (66%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P ++NDG P L LG + S+ DT VR A IE GYRHIDTAA+YG+EE VG Sbjct: 9 PTLEMNDGKTTPQLGLGVWQ--LSDEDTYTSVRAA----IETGYRHIDTAAIYGNEEAVG 62 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + +A+A+ G V RE+LFITTKLWN A G+ ES ++LG+DYVDLYL+H+P Sbjct: 63 RAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP 117 >UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 320 Score = 116 bits (279), Expect = 3e-25 Identities = 63/142 (44%), Positives = 88/142 (61%), Gaps = 1/142 (0%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 +++ P L++G +P + LGT + T E T+ +R AV AGYRHIDTA +Y +E Sbjct: 2 SSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTV--IRNAVL----AGYRHIDTATLYQNE 55 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 Q+G +AE A+G++ RED+FITTK + + A V LR SL+RL LDYVDLYL H Sbjct: 56 HQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHI 115 Query: 446 PISSKADGS-PDNIDYLETWEG 508 P S+K DGS ++ + W G Sbjct: 116 PASTKDDGSFRSDVKVEDIWRG 137 >UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18; n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member C18 - Mus musculus (Mouse) Length = 323 Score = 115 bits (277), Expect = 5e-25 Identities = 63/146 (43%), Positives = 85/146 (58%), Gaps = 11/146 (7%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LNDG+ IPVL GT A+E + ++ AI+ G+ HID + +Y +EE++GQ I Sbjct: 9 ELNDGHSIPVLGFGT---YATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAI 65 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 I G V RED+F T+KLW+ H V P+L SL++L LDYVDLYLIHFP+S K Sbjct: 66 LSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPG 125 Query: 467 GS--P---------DNIDYLETWEGM 511 P D +D +TWE M Sbjct: 126 NELLPKDEHGNLIFDTVDLCDTWEAM 151 >UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus sp. (strain CC9311) Length = 336 Score = 115 bits (276), Expect = 7e-25 Identities = 62/144 (43%), Positives = 93/144 (64%), Gaps = 10/144 (6%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++G ++P+L LGTG+ SES QV ++V AI+ GYRHID A++YG+EE+VG I Sbjct: 24 LSNGDRMPLLGLGTGK---SESR---QVYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 +AI +TR +L+IT+KLW++ H + V L +SLQ LG+DY++LYLIH+P+ + + Sbjct: 78 DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEK 137 Query: 470 ----------SPDNIDYLETWEGM 511 +P+ ETWE M Sbjct: 138 TFAESVDDLLTPEESPISETWEAM 161 >UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea) Length = 321 Score = 115 bits (276), Expect = 7e-25 Identities = 59/125 (47%), Positives = 85/125 (68%), Gaps = 1/125 (0%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G K+PVL LGT + +T VR+AV A++ GYRH DTAA+Y E+ +G IAEA+ Sbjct: 14 GRKMPVLGLGTAADPPVDPET---VRKAVTEALKLGYRHFDTAALYNSEQPLGDAIAEAL 70 Query: 299 AKGLV-TREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSP 475 +GL+ +R++LFIT+KLW R V P L+++L+ L L+Y+D+YLIH+P+SSK P Sbjct: 71 GEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSK----P 126 Query: 476 DNIDY 490 N +Y Sbjct: 127 GNYEY 131 >UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 323 Score = 115 bits (276), Expect = 7e-25 Identities = 55/118 (46%), Positives = 78/118 (66%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G IP +ALGT + + E V AV AIE GYRHID A +YG+E ++G+ + Sbjct: 9 KLNTGASIPAMALGTWQSSKEE------VGNAVRLAIELGYRHIDCAEIYGNEGEIGEAL 62 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 +E + +G V RE+LF+T+KLW D H V+P + +L+ L LDY+DLYLIH P++ K Sbjct: 63 SEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFK 120 >UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|Rep: Aldehyde reductase - Croceibacter atlanticus HTCC2559 Length = 316 Score = 114 bits (275), Expect = 1e-24 Identities = 60/136 (44%), Positives = 89/136 (65%), Gaps = 3/136 (2%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 + DG IP + LGT + SD D V++AV A+E GY+HID AA Y +E+ VG+ Sbjct: 5 KFRDGDSIPSIGLGTWK-----SDPED-VKKAVKIALENGYKHIDCAAAYDNEDAVGEAF 58 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK-- 460 E+ G V RED+F+T+KLWN+ H + V+P L+++L+ L LDY+DLYL+H+P++ K Sbjct: 59 KESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPS 118 Query: 461 ADGSPD-NIDYLETWE 505 +G P+ + DYL E Sbjct: 119 VNGFPEKDEDYLSLEE 134 >UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebacterium|Rep: Putative oxidoreductase - Corynebacterium diphtheriae Length = 290 Score = 113 bits (273), Expect = 2e-24 Identities = 57/121 (47%), Positives = 77/121 (63%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P LNDG ++P + GT + E D VR A IE GYRHIDTA++Y +EE+VG Sbjct: 12 PTITLNDGTEMPAIGFGTYK--LREQDAYRAVRSA----IEVGYRHIDTASLYKNEEEVG 65 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 + +A+AI G V R++LFITTK+WND H + +ESL RLGLDY+D ++H+P Sbjct: 66 RAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQ 125 Query: 458 K 460 K Sbjct: 126 K 126 >UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo sapiens (Human) Length = 325 Score = 113 bits (273), Expect = 2e-24 Identities = 62/151 (41%), Positives = 91/151 (60%), Gaps = 12/151 (7%) Frame = +2 Query: 95 APCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQV 274 A C L+ G K+P++ LGT + QV+ AV +A+ GYRHID AA+YG+E ++ Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEPG------QVKAAVKYALSVGYRHIDCAAIYGNEPEI 56 Query: 275 GQGIAEAIAKG-LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 G+ + E + G V RE+LF+T+KLWN KH V P LR++L L L+Y+DLYL+H+P Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116 Query: 452 S---------SKADGS--PDNIDYLETWEGM 511 + ADG+ D+ Y ETW+ + Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKAL 147 >UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep: Aldose reductase - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 312 Score = 113 bits (271), Expect = 3e-24 Identities = 60/123 (48%), Positives = 81/123 (65%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN G KIP LGT +G +++AV AI++GYR ID A VYG+EE+VGQGI Sbjct: 8 LNTGAKIPAFGLGTWQGDKGV------IKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIR 61 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 EAI+ G+V REDLF+ +K W R ++ L +SL+ LGLDYVDLYL+H+PI +G Sbjct: 62 EAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMNPEG 119 Query: 470 SPD 478 + + Sbjct: 120 NDE 122 >UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons|Rep: Chalcone reductase - Sesbania rostrata Length = 322 Score = 112 bits (270), Expect = 4e-24 Identities = 54/121 (44%), Positives = 85/121 (70%), Gaps = 2/121 (1%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFW-AIEAGYRHIDTAAVYGDEEQVGQGI 286 LN G+K+PV+ G GT+ ES + V ++F AI+ GYRH D+A+VYG EE +G + Sbjct: 11 LNSGHKMPVI----GMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMAV 66 Query: 287 AEAIAKGLV-TREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 ++AI +GL+ +R+++FIT+K WN +VP L+ +L++LG++YVDLYLIH+P+ + Sbjct: 67 SKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLRH 126 Query: 464 D 466 D Sbjct: 127 D 127 >UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA19341-PA - Drosophila pseudoobscura (Fruit fly) Length = 315 Score = 112 bits (270), Expect = 4e-24 Identities = 65/150 (43%), Positives = 89/150 (59%), Gaps = 12/150 (8%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P L+ G +P++ LGT R + V QAV AI+ GYRH D A +YG+E VG Sbjct: 4 PSFLLSSGRNMPMVGLGTWRSPP------EVVAQAVKDAIDIGYRHFDCAHIYGNELHVG 57 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 I E I +GLVTR++LFIT+KLWN H V SL+ LG+DY+DLYL+H+P++ Sbjct: 58 VAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAY 117 Query: 458 KADGS-----PD-------NIDYLETWEGM 511 K+ + PD +IDYL+TW+ M Sbjct: 118 KSGDNLYPTCPDTGKAVFEDIDYLDTWKAM 147 >UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13; n=11; Theria|Rep: Aldo-keto reductase family 1 member C13 - Mus musculus (Mouse) Length = 323 Score = 112 bits (270), Expect = 4e-24 Identities = 62/147 (42%), Positives = 86/147 (58%), Gaps = 12/147 (8%) Frame = +2 Query: 101 CHQLNDGYKIPVLALGTGRGT-ASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 C +LNDG+ IP L GT + +S +L+ A A++ GYRH+DTA Y EE++G Sbjct: 7 CVKLNDGHLIPALGFGTYKPKEVPKSKSLE----AACLALDVGYRHVDTAYAYQVEEEIG 62 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 Q I I G+V REDLFITTKLW V P L +SL++L LDYVDLY++H+P+ Sbjct: 63 QAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPM 122 Query: 458 KADGSP-----------DNIDYLETWE 505 K+ + D +D+ +TWE Sbjct: 123 KSGDNDFPVNEQGKSLLDTVDFCDTWE 149 >UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 360 Score = 112 bits (269), Expect = 5e-24 Identities = 55/121 (45%), Positives = 84/121 (69%), Gaps = 1/121 (0%) Frame = +2 Query: 152 GRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLF 331 G GT + + + +AV +AIE GYR ID AAVYG+E VG+GI E + + + RED++ Sbjct: 43 GFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIW 102 Query: 332 ITTKLWNDKHARGQ-VVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNIDYLETWEG 508 +T+KLWND H + V L ++LQ LGL+Y+DLYLIH+PI ++G+ N+D+++T++ Sbjct: 103 VTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA-KNLDHVQTYKS 161 Query: 509 M 511 M Sbjct: 162 M 162 >UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza sativa (Rice) Length = 323 Score = 111 bits (268), Expect = 7e-24 Identities = 56/115 (48%), Positives = 79/115 (68%), Gaps = 1/115 (0%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G +P + +GT A+ +T R A A+E G+RH DTAA+YG E +G+ IAEA Sbjct: 14 GRPMPAVGVGTADSAATSPETK---RGAALAALEVGFRHFDTAALYGTEAPLGEAIAEAT 70 Query: 299 AKGLV-TREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 +GLV +RE++F+TTKLW + G V+P+LRESL+ L ++YVDLYL+H+PIS K Sbjct: 71 RRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVK 125 >UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9 protein - Oryza sativa (Rice) Length = 337 Score = 111 bits (268), Expect = 7e-24 Identities = 67/147 (45%), Positives = 86/147 (58%), Gaps = 2/147 (1%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVY 256 + + PC LN G+ +PVL GTG T + + A+ GYRH+DTAAVY Sbjct: 14 AAAATAVPCVTLNSGHAMPVLGFGTGSSTPPAD-----LAATIAHAVRLGYRHLDTAAVY 68 Query: 257 GDEEQVGQGIAEAIAKGLV-TREDLFITTKL-WNDKHARGQVVPTLRESLQRLGLDYVDL 430 G E VG +AEA+ G V +R +LF+TTKL D H +VV LRESL RLGLDYVDL Sbjct: 69 GTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPP-RVVAALRESLSRLGLDYVDL 127 Query: 431 YLIHFPISSKADGSPDNIDYLETWEGM 511 +LIH+P+ A G D L TW+ + Sbjct: 128 FLIHWPV---AIGKKDAAGEL-TWDDL 150 >UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; Oryza sativa (japonica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. japonica (Rice) Length = 288 Score = 111 bits (268), Expect = 7e-24 Identities = 55/128 (42%), Positives = 83/128 (64%), Gaps = 1/128 (0%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+ G +P + +GT +D V+ V AIEAGYRH DTAAVY E +G +A Sbjct: 6 LSSGKPMPRVGMGTASFPLGATDP-STVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVA 64 Query: 290 EAIAKGLV-TREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 EA+ GLV +R++L+IT+KLW G V+P+LR +L+++ ++Y+DLYLIHFP+S + Sbjct: 65 EAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVSMRLA 124 Query: 467 GSPDNIDY 490 P+++ Y Sbjct: 125 EDPESMTY 132 >UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent D-sorbitol-6-phosphate dehydrogenase - Malus domestica (Apple) (Malus sylvestris) Length = 310 Score = 111 bits (268), Expect = 7e-24 Identities = 57/117 (48%), Positives = 77/117 (65%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+ GY++PV+ LG R E D L +V + AI+ GYRH D AA Y E VG+ +A Sbjct: 6 LSSGYEMPVIGLGLWR---LEKDELKEV---ILNAIKIGYRHFDCAAHYKSEADVGEALA 59 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 EA GLV RE+LFITTK+WN H G VV + SL++L +DY+DLYL+H+P+ +K Sbjct: 60 EAFKTGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTK 114 >UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica; n=3; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome F of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 324 Score = 111 bits (267), Expect = 9e-24 Identities = 64/134 (47%), Positives = 84/134 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LNDG+ IP L LGT AS+ + V + V+ AI+ GYRHIDTA +YG E VG+GI Sbjct: 8 KLNDGHSIPALGLGT----ASDGN----VEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 AI + LV RE+LF+TTK+W + R V +L SL+ L LDYVDL L+H+P+S AD Sbjct: 60 KRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLAD 117 Query: 467 GSPDNIDYLETWEG 508 YL +G Sbjct: 118 SDDPRAIYLVNTDG 131 >UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent 6'-deoxychalcone synthase - Glycine max (Soybean) Length = 315 Score = 111 bits (266), Expect = 1e-23 Identities = 51/112 (45%), Positives = 80/112 (71%) Frame = +2 Query: 125 KIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAK 304 ++PV+ +G+ + DT ++A+ A++ GYRH DTAA YG E+ +G+ + EAI Sbjct: 20 RMPVVGMGSAPDFTCKKDT----KEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHL 75 Query: 305 GLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 GLV+R+DLF+T+KLW ++ V+P LR+SL+ L L+Y+DLYLIH+P+SS+ Sbjct: 76 GLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQ 127 >UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 286 Score = 110 bits (264), Expect = 2e-23 Identities = 63/136 (46%), Positives = 84/136 (61%) Frame = +2 Query: 104 HQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQG 283 + LN+G KIP++ GT + T D +V A++AGYRHIDTAA YG+EE VG+ Sbjct: 11 YTLNNGTKIPIVGFGTWQ-TPDGQVAYD----SVLAALKAGYRHIDTAAAYGNEESVGKA 65 Query: 284 IAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 IA++ G V REDLF+TTKLWN H L SL +LGLDYVDLYLIH+P + Sbjct: 66 IADS---G-VAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAM 121 Query: 464 DGSPDNIDYLETWEGM 511 + + ++ +TW M Sbjct: 122 RDNWEQLN-ADTWRAM 136 >UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Opitutaceae bacterium TAV2 Length = 347 Score = 109 bits (263), Expect = 3e-23 Identities = 53/124 (42%), Positives = 75/124 (60%), Gaps = 1/124 (0%) Frame = +2 Query: 80 VSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYG 259 + A+ P L G ++P + +GT S+ +V +V+ A E GYRH D AAVY Sbjct: 11 IDPAKIPQRTLASGARMPAIGMGT---FGSDHAAPGEVAASVYAAAELGYRHFDCAAVYS 67 Query: 260 DEEQVGQGIAEAIAKGL-VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYL 436 +E ++G + + REDL+IT+KLWNDKHA V+P +SL+ LGLDY+DLYL Sbjct: 68 NEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYL 127 Query: 437 IHFP 448 IH+P Sbjct: 128 IHWP 131 >UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|Rep: ENSANGP00000031808 - Anopheles gambiae str. PEST Length = 316 Score = 109 bits (262), Expect = 4e-23 Identities = 64/144 (44%), Positives = 83/144 (57%), Gaps = 12/144 (8%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G IP+ LGT QV QAV AI+ GYRHID A VY +E +VG+GIA Sbjct: 13 NGNSIPMFGLGTWNSPPG------QVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAK 66 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK----- 460 IA+G+V REDLF+T+KLWN H V + +LQ L LDY+DLYLIH+P+ + Sbjct: 67 IAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTEL 126 Query: 461 ----ADGSP---DNIDYLETWEGM 511 DG + DY++TW M Sbjct: 127 FPMGPDGKTFLFSDADYVDTWPEM 150 >UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 324 Score = 109 bits (262), Expect = 4e-23 Identities = 56/124 (45%), Positives = 77/124 (62%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +LN+G ++P + LGT D+ +AV AI+ G+RHIDTA Y +E+ VG Sbjct: 7 PTVKLNNGLEMPAIGLGTSMSKG------DECCKAVMTAIDEGFRHIDTAYNYRNEDVVG 60 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 + I I +G+VTRE+LF+TTKLWN H V +SL+ LGLDYVDL+LIH P Sbjct: 61 RAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGY 120 Query: 458 KADG 469 + +G Sbjct: 121 EFNG 124 >UniRef50_P22045 Cluster: Probable reductase; n=101; cellular organisms|Rep: Probable reductase - Leishmania major Length = 284 Score = 109 bits (262), Expect = 4e-23 Identities = 61/131 (46%), Positives = 79/131 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++G K+P LG + A E AV WA+ AGYRHIDTAA+Y +EE VG G+ Sbjct: 11 LSNGVKMPQFGLGVWQSPAGEV-----TENAVNWALCAGYRHIDTAAIYKNEESVGAGLR 65 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 A G V RED+FITTKLWN + + ES Q+LG+DY+DLYLIH+P K Sbjct: 66 ---ASG-VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP-RGKDIL 120 Query: 470 SPDNIDYLETW 502 S + YL++W Sbjct: 121 SKEGKKYLDSW 131 >UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase A - Corynebacterium sp. (strain ATCC 31090) Length = 278 Score = 109 bits (262), Expect = 4e-23 Identities = 65/138 (47%), Positives = 83/138 (60%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P LNDG IP L G + +DT ++AV A+E GYRHIDTAA+YG+EE VG Sbjct: 4 PSIVLNDGNSIPQLGYGVFK--VPPADT----QRAVEEALEVGYRHIDTAAIYGNEEGVG 57 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 IA A G + R+DLFITTKLWND+H + + ESL +L LD VDLYL+H+P Sbjct: 58 AAIA---ASG-IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP--- 110 Query: 458 KADGSPDNIDYLETWEGM 511 +P +Y+ WE M Sbjct: 111 ----TPAADNYVHAWEKM 124 >UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA - Drosophila melanogaster (Fruit fly) Length = 322 Score = 109 bits (261), Expect = 5e-23 Identities = 61/151 (40%), Positives = 89/151 (58%), Gaps = 13/151 (8%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P L++G +P+L LGT R + V QAV AI+ GYRH D A +YG+E QVG Sbjct: 4 PNFLLSNGKNMPMLGLGTWRSPP------EVVTQAVKDAIDIGYRHFDCAHIYGNEAQVG 57 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 + E + +G+VTR++LFIT+KLWN H V P S++ LG+ Y++LYL+H+P++ Sbjct: 58 AALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAY 117 Query: 458 KADGS------PD-------NIDYLETWEGM 511 K+ PD +IDY++TW M Sbjct: 118 KSGSDNLYPTCPDTNKAAFEDIDYVDTWRAM 148 >UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid dehydrogenase - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 324 Score = 107 bits (258), Expect = 1e-22 Identities = 53/118 (44%), Positives = 74/118 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LNDG+K+PV+ GT ++ + AI+ GYRHID A +YG+EE+VG+ I Sbjct: 10 ELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKV---AIDVGYRHIDCAFLYGNEEEVGRAI 66 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 IA G V RED+F T KLW+ H +V P L +SL+ L LDY+DL++IH P+ K Sbjct: 67 RAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFK 124 >UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae str. PEST Length = 319 Score = 107 bits (258), Expect = 1e-22 Identities = 60/157 (38%), Positives = 91/157 (57%), Gaps = 15/157 (9%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 + Q P + ++GY+IPVL GT A + ++ V++A I+ GYRHIDTA +Y +E Sbjct: 2 STQVPTVRFSNGYEIPVLGYGTY--LAQKGQCVELVKKA----IDLGYRHIDTAFLYENE 55 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 ++GQ I + IA+G++ RED+F+TTKLWN H V R S L + Y+DL+L+H Sbjct: 56 VEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHS 115 Query: 446 PISSK------ADGSP---------DNIDYLETWEGM 511 P+ + AD P ++DY+ETW+ M Sbjct: 116 PMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAM 152 >UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: Aldehyde reductase - Leptospira interrogans Length = 278 Score = 107 bits (257), Expect = 1e-22 Identities = 55/117 (47%), Positives = 77/117 (65%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G +P+L LG + + + + ++AV A+EAGYRHIDTA +Y +E VGQ I Sbjct: 14 LNNGISMPILGLGVWKTKSGK-----ECKEAVLNALEAGYRHIDTARIYDNEVDVGQAIR 68 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 E+ G + R+++FITTKLWN + L SL RLG+D+VDLYLIHFP++SK Sbjct: 69 ES---G-IPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSK 121 >UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5; Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 321 Score = 106 bits (255), Expect = 3e-22 Identities = 53/121 (43%), Positives = 75/121 (61%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +LN GY +P++ G + + DQ+ + AI+AGYR D A YG+E + G Sbjct: 4 PSTKLNSGYDMPLVGFGLWK--VNNETCADQI----YHAIKAGYRLFDGACDYGNEVEAG 57 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 +G+A AI +G+V REDLFI +KLWN H +V P R+ L GLDY DL+++HFPI+ Sbjct: 58 KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117 Query: 458 K 460 K Sbjct: 118 K 118 >UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 293 Score = 105 bits (252), Expect = 6e-22 Identities = 52/119 (43%), Positives = 74/119 (62%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 +N+G++IP L LG + D + + A+ WA+ AGYRHIDTAA YG+E+ VG Sbjct: 16 MNNGHQIPQLGLGV-----FQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVG---- 66 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 EAI + V R+ +F+T+KLWN + +E+L +LGLDY+DLYLIH+P D Sbjct: 67 EAIRESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAPGYLD 125 >UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium discoideum|Rep: Aldehyde reductase - Dictyostelium discoideum AX4 Length = 297 Score = 105 bits (252), Expect = 6e-22 Identities = 61/147 (41%), Positives = 87/147 (59%), Gaps = 9/147 (6%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +L+ G+KIP++ GT + TL V +AV A++AGYRHID AAVY +E++VG Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAET----TL--VGKAVEVALDAGYRHIDCAAVYLNEKEVG 56 Query: 278 QGIAEAIA-KGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 + + + V RED+FIT+KLWN H + V P L +L LGL Y+DLYL+H+P++ Sbjct: 57 EAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVA 116 Query: 455 -------SKADGSPDN-IDYLETWEGM 511 + GS + ETWE M Sbjct: 117 FEYTSNDIQTSGSTQEFVSIRETWEEM 143 >UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate division TM7 genomosp. GTL1|Rep: Aldehyde reductase - candidate division TM7 genomosp. GTL1 Length = 299 Score = 105 bits (251), Expect = 8e-22 Identities = 47/92 (51%), Positives = 68/92 (73%) Frame = +2 Query: 212 AIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLR 391 AI+AGYRHID A +YG+E++VG+GI I +G+V REDLF+T+KLWN HA+ V R Sbjct: 34 AIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACR 93 Query: 392 ESLQRLGLDYVDLYLIHFPISSKADGSPDNID 487 ++L LGLDY+DLYLIH+ ++ + + + +D Sbjct: 94 KTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLD 125 >UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyledons|Rep: T2K10.1 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 176 Score = 104 bits (250), Expect = 1e-21 Identities = 54/115 (46%), Positives = 75/115 (65%), Gaps = 2/115 (1%) Frame = +2 Query: 122 YKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIA 301 + +PVL GT E L ++ V AI+ GYRH DT+ Y EE +G+ +AEA++ Sbjct: 19 HSMPVLGFGTAASPLPEPTML---KETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVS 75 Query: 302 KGLV-TREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 GLV +R + F+TTKLW D H G VVP ++ SL+ L LDY+DLY+IH+P+SSK Sbjct: 76 LGLVRSRSEFFVTTKLWCADAHG-GLVVPAIKRSLKNLKLDYLDLYIIHWPVSSK 129 >UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase 1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent oxidoreductase 1 - Oryza sativa subsp. japonica (Rice) Length = 321 Score = 104 bits (250), Expect = 1e-21 Identities = 55/116 (47%), Positives = 79/116 (68%), Gaps = 3/116 (2%) Frame = +2 Query: 152 GRGTASESDTLDQ-VRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLV-TRED 325 G GTA+ T + A+ AIE GYRH DTA +Y E VG+ +AEA+ +GL+ +R D Sbjct: 20 GMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRAD 79 Query: 326 LFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNIDY 490 +F+T+K+W +D HA G+VVP RE+L+ LG+DYVDL L+H+P+S +P N D+ Sbjct: 80 VFVTSKIWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPVSL----TPGNYDF 130 >UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like protein 1; n=14; Eutheria|Rep: Aldo-keto reductase family 1 member C-like protein 1 - Homo sapiens (Human) Length = 302 Score = 104 bits (249), Expect = 1e-21 Identities = 56/121 (46%), Positives = 73/121 (60%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LNDG +PVL GT A + Q +A AI+ G+RHID+A +Y +EE+VGQ I Sbjct: 12 RLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAI 68 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 E IA G V RE++F T KLW V P L SL++LG DYVDL++IH P + K Sbjct: 69 WEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQP 128 Query: 467 G 469 G Sbjct: 129 G 129 >UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotina|Rep: Aldehyde reductase - Coccidioides posadasii Length = 314 Score = 103 bits (248), Expect = 2e-21 Identities = 58/146 (39%), Positives = 88/146 (60%), Gaps = 11/146 (7%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G IP + GT + ++ D AV A+ AGYRHIDTAAVYG E+ +G+ Sbjct: 9 RLNTGEDIPAIGFGTWQDENAQED-------AVLTALSAGYRHIDTAAVYGTEKAIGR-- 59 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH-------- 442 A+A+ ++R++LFIT+KLWN+KH V + +SL+ L +DY+DLYL+H Sbjct: 60 --ALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPG 117 Query: 443 ---FPISSKADGSPDNIDYLETWEGM 511 FP S+ + +IDY++T++ M Sbjct: 118 DDMFPKDSQGNSKTVDIDYVDTYKAM 143 >UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: Aldose reductase - Mus musculus (Mouse) Length = 316 Score = 103 bits (247), Expect = 2e-21 Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 11/146 (7%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G K+P L LGT + QV +AV AI+ GYRHID A VY +E++VG + Sbjct: 6 ELNNGTKMPTLGLGTWKSPPG------QVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVAL 59 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH-------- 442 E + + +V R+DLFI +KLW H + V +++L L LDY+DLYLIH Sbjct: 60 QEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPG 119 Query: 443 ---FPISSKADGSPDNIDYLETWEGM 511 FP+ + + P + D+++TW M Sbjct: 120 PDYFPLDASGNVIPSDTDFVDTWTAM 145 >UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 protein; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to LOC553452 protein - Strongylocentrotus purpuratus Length = 321 Score = 103 bits (246), Expect = 3e-21 Identities = 62/147 (42%), Positives = 83/147 (56%), Gaps = 13/147 (8%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L G K+P+L GT + E V + + AI+ GYRHID A++YG+E+ VG GI Sbjct: 10 LPGGRKLPLLGFGTWQIKPEE------VGRVIETAIDCGYRHIDEASLYGNEKGVGDGIK 63 Query: 290 EAIAKGLVTREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 I G + REDLF+T+KLW D H +V P+ R+SL LGL Y+DL+LIH P S+ Sbjct: 64 AKIDDGTIKREDLFVTSKLWVTDSHP-SRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGG 122 Query: 467 GSP------------DNIDYLETWEGM 511 P D IDY++TW M Sbjct: 123 KGPFPMDDNGLFIGDDTIDYVDTWRIM 149 >UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 323 Score = 103 bits (246), Expect = 3e-21 Identities = 66/150 (44%), Positives = 84/150 (56%), Gaps = 12/150 (8%) Frame = +2 Query: 98 PCH-QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQV 274 P H +N G KIP + GT + E V AV A+ GYRHID AA+Y +E +V Sbjct: 4 PSHFTINTGAKIPAVGFGTWQAKPLE------VENAVEVALREGYRHIDCAAIYRNETEV 57 Query: 275 GQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 G GI K V RE++FIT KLWN KHA V P L ++LQ LG+ Y+DLYL+H+P + Sbjct: 58 GNGIR----KSGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCA 113 Query: 455 SKA---------DGSPD--NIDYLETWEGM 511 K DG D NIDY+ T+ M Sbjct: 114 FKGGDKWFPLNDDGVFDLANIDYITTYRAM 143 >UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; n=39; cellular organisms|Rep: NADPH-dependent aldose reductase GRE3 - Saccharomyces cerevisiae (Baker's yeast) Length = 327 Score = 103 bits (246), Expect = 3e-21 Identities = 51/117 (43%), Positives = 80/117 (68%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G K+P++ LG + + +Q+ +A I+ GYR D A YG+E++VG+GI Sbjct: 7 LNNGLKMPLVGLGCWK--IDKKVCANQIYEA----IKLGYRLFDGACDYGNEKEVGEGIR 60 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 +AI++GLV+R+D+F+ +KLWN+ H V L+++L +GLDY+DLY IHFPI+ K Sbjct: 61 KAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117 >UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: Aldose reductase - Homo sapiens (Human) Length = 316 Score = 103 bits (246), Expect = 3e-21 Identities = 59/145 (40%), Positives = 82/145 (56%), Gaps = 11/145 (7%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G K+P+L LGT + QV +AV AI+ GYRHID A VY +E +VG I Sbjct: 7 LNNGAKMPILGLGTWKSPPG------QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH--------- 442 E + + +V RE+LFI +KLW H +G V +++L L LDY+DLYLIH Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 Query: 443 --FPISSKADGSPDNIDYLETWEGM 511 FP+ + P + + L+TW M Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAM 145 >UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropicalis|Rep: LOC594893 protein - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 345 Score = 102 bits (245), Expect = 4e-21 Identities = 61/143 (42%), Positives = 76/143 (53%), Gaps = 11/143 (7%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 D P GT GT E +D VR A A++ GYRH+D A +Y E VGQ E Sbjct: 33 DSQANPGHCAGTKHGT--EKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREK 90 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK----- 460 A G + REDLF T+KLWN H V P L ++L L +DYVDLYLIH P+S K Sbjct: 91 FADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEEL 150 Query: 461 ----ADGSP--DNIDYLETWEGM 511 DG+ D D L+TW+ + Sbjct: 151 FPKNEDGTCAFDQPDLLQTWQAL 173 >UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy chain; n=3; Saccharomycetaceae|Rep: D-arabinose dehydrogenase [NAD(P)+] heavy chain - Saccharomyces cerevisiae (Baker's yeast) Length = 344 Score = 102 bits (245), Expect = 4e-21 Identities = 60/128 (46%), Positives = 78/128 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G +IP L LGT A+ + L + +QAV AI+AGYRHIDTA Y E VG+ I Sbjct: 27 LNNGVRIPALGLGT----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 E + G + REDLFITTK+W +V +L ESL+ LGL+YVDL L H+P+ + Sbjct: 83 ELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 Query: 470 SPDNIDYL 493 P I L Sbjct: 141 DPKGISGL 148 >UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: Aldehyde reductase 1 - Sporobolomyces salmonicolor Length = 323 Score = 102 bits (245), Expect = 4e-21 Identities = 55/120 (45%), Positives = 74/120 (61%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN G + ++ GT + E V Q V AIE GYRH+D A VY ++ +VG I Sbjct: 7 LNTGASLELVGYGTWQAAPGE------VGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK 60 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 EA K REDLFIT+KLWN+ H QV P L ++L+ LGL+Y+DLYLIH+P++ +G Sbjct: 61 EAGVK----REDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEG 116 >UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20; Corynebacterineae|Rep: 2,5-didehydrogluconate reductase - Mycobacterium sp. (strain KMS) Length = 283 Score = 102 bits (244), Expect = 5e-21 Identities = 62/141 (43%), Positives = 86/141 (60%) Frame = +2 Query: 89 AQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 A P LNDG+ IPVL LG G + +E++ ++V A+EAGYR IDTAAVYG+E Sbjct: 9 AGIPSVSLNDGHSIPVLGLGVGELSEAEAE------RSVAAALEAGYRLIDTAAVYGNEA 62 Query: 269 QVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 VG+ + A G + RE++++TTKL G R SL+RLGLDYVDLYLIH+P Sbjct: 63 AVGRAVN---ASG-IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118 Query: 449 ISSKADGSPDNIDYLETWEGM 511 + D+ Y+++W G+ Sbjct: 119 -------AGDHGKYIDSWGGL 132 >UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core eudicotyledons|Rep: Aldose reductase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 102 bits (244), Expect = 5e-21 Identities = 56/144 (38%), Positives = 81/144 (56%), Gaps = 9/144 (6%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L G IP+L +GT T+ V QA I+ GYRH DTA +YG EE +G + Sbjct: 7 RLRCGETIPLLGMGTYCPQKDRESTISAVHQA----IKIGYRHFDTAKIYGSEEALGTAL 62 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS---- 454 +AI+ G V R+DLF+T+KLW+ H + L ++L+ +GLDY+D YL+H+PI Sbjct: 63 GQAISYGTVQRDDLFVTSKLWSSDH--HDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG 120 Query: 455 -----SKADGSPDNIDYLETWEGM 511 K D ++ ETW+GM Sbjct: 121 VSEPIPKEDEFEKDLGIEETWQGM 144 >UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 333 Score = 101 bits (243), Expect = 7e-21 Identities = 56/147 (38%), Positives = 84/147 (57%), Gaps = 13/147 (8%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L G+ +P++ LGT + A D+V A+ A++AGYRH D A +YG+E++VG + Sbjct: 7 LPSGHAMPLVGLGTWKLKA------DEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALR 60 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 EA+ + + RED+FITTK+WN HA+ V SL L LDY+DLY++H+P+ + G Sbjct: 61 EAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLG 120 Query: 470 SP-------------DNIDYLETWEGM 511 ++ YLETW M Sbjct: 121 PTVMFPRTETGDIVYSDVHYLETWSAM 147 >UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 101 bits (243), Expect = 7e-21 Identities = 60/122 (49%), Positives = 76/122 (62%), Gaps = 1/122 (0%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAI-EAGYRHIDTAAVYGDEEQVGQGI 286 LN+G IP + LGT + T E V AV A+ E GYRHIDTA Y +E+ VG GI Sbjct: 36 LNNGKTIPAIGLGTWKSTTEE------VAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 A+ KG V RED+F+TTK+W H R V L SL+RLGLDYVD+ LIH+P+ + Sbjct: 90 KRAMEKG-VKREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNPN 146 Query: 467 GS 472 G+ Sbjct: 147 GN 148 >UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase 2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent oxidoreductase 2 - Oryza sativa subsp. japonica (Rice) Length = 322 Score = 101 bits (243), Expect = 7e-21 Identities = 56/112 (50%), Positives = 78/112 (69%), Gaps = 3/112 (2%) Frame = +2 Query: 152 GRGTASESDTL-DQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLV-TRED 325 G GTA+ T ++ A+ AIE GYRH DTA +Y E V + +AEA+ +GLV +R D Sbjct: 22 GMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRAD 81 Query: 326 LFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPD 478 +F+T+KLW +D HA G+VVP RE+L+ LG+DYVDL L+H+P ++ A GS D Sbjct: 82 VFVTSKLWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWP-ATVAPGSYD 131 >UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose reductase - Hordeum vulgare (Barley) Length = 320 Score = 101 bits (243), Expect = 7e-21 Identities = 56/121 (46%), Positives = 78/121 (64%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L G+ +P + LGT R + SDT VR A+ EAGYRH+DTAA YG E++VG+G+ Sbjct: 18 LKSGHAMPAVGLGTWR---AGSDTAHSVRTAI---TEAGYRHVDTAAEYGVEKEVGKGLK 71 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 A+ G + R+DLF+T+K+W A +V P L +L+ L LDY+DLY IH+P K DG Sbjct: 72 AAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DG 129 Query: 470 S 472 + Sbjct: 130 A 130 >UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG2767-PA - Drosophila melanogaster (Fruit fly) Length = 329 Score = 101 bits (242), Expect = 9e-21 Identities = 55/122 (45%), Positives = 80/122 (65%), Gaps = 2/122 (1%) Frame = +2 Query: 113 NDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAE 292 N+G K+PV+ +GT + + E +T A+ A+EAGYRHIDTA VYG+E+ +G+ + Sbjct: 10 NNGEKMPVIGIGTWQASDEEIET------AIDAALEAGYRHIDTAPVYGNEKAIGRVLKR 63 Query: 293 AIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH--FPISSKAD 466 + G V RE+LFI TK+ + +V PT+++SL+ L LDYVDLYL+H F I+ D Sbjct: 64 WLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININED 123 Query: 467 GS 472 GS Sbjct: 124 GS 125 >UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; Schizosaccharomyces pombe|Rep: Probable oxidoreductase C26F1.07 - Schizosaccharomyces pombe (Fission yeast) Length = 321 Score = 101 bits (242), Expect = 9e-21 Identities = 58/117 (49%), Positives = 79/117 (67%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L DG KIP L LGT R SE + Q + AV A++ GYRHID AA+YG+E++VG GI Sbjct: 18 LADGSKIPGLGLGTWR---SEPN---QTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGIK 71 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 E+ G V R+D+++T+KLW + HA V L ++L+ L LDY+D YLIH+P+S K Sbjct: 72 ES---G-VPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFK 124 >UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep: Protein GCY - Saccharomyces cerevisiae (Baker's yeast) Length = 312 Score = 101 bits (241), Expect = 1e-20 Identities = 57/113 (50%), Positives = 79/113 (69%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN G +IP + LGT + + E+D +AV A++ GYRHIDTAA+Y +E+QVGQ I Sbjct: 14 LNTGAQIPQIGLGTWQ--SKENDAY----KAVLTALKDGYRHIDTAAIYRNEDQVGQAIK 67 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 ++ G V RE++F+TTKLW +H +V L +SL+RLGLDYVDLYL+H+P Sbjct: 68 DS---G-VPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWP 114 >UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=3; Lactobacillales|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 292 Score = 100 bits (240), Expect = 2e-20 Identities = 53/113 (46%), Positives = 72/113 (63%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L G ++P+L G + E +QAV AI+ GYR IDTAA YG+E +VG+ I Sbjct: 6 LASGIEMPLLGFGVFQ--VQEKGA---AKQAVLDAIKTGYRLIDTAASYGNEREVGEAIL 60 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 EAI +G+V RE+LF+T+K+W + Q ++ SLQRL LDY+DLYLIH P Sbjct: 61 EAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP 113 >UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Aldo/keto reductase of diketogulonate reductase family - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 288 Score = 100 bits (240), Expect = 2e-20 Identities = 53/113 (46%), Positives = 72/113 (63%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G ++P L G + A E+ +QAV AI AGYR IDTA VYG+E + GQG+ Sbjct: 6 LNNGAQMPQLGFGVFQIPAEET------KQAVVDAINAGYRSIDTARVYGNEAETGQGVN 59 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 EAIA +V RE+LF+TTKLW + + + +SL++LG DY DL L+H P Sbjct: 60 EAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQP 112 >UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep: Catalytic activity: an alcohol + NADP(+) <=> an aldehyde + NADPH - Aspergillus niger Length = 345 Score = 100 bits (240), Expect = 2e-20 Identities = 53/116 (45%), Positives = 74/116 (63%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN GY +P + LGT + D+VR AV A++ GYRHID AAVYG+E++VG G+ Sbjct: 8 KLNTGYDMPAVGLGTWQSKK------DEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 G V RE++F+T+KLWN H V + +SL L DY+DLYLIH+P++ Sbjct: 62 R---LSG-VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVA 113 >UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "AKR1B1 protein. - Takifugu rubripes Length = 330 Score = 99 bits (238), Expect(2) = 2e-20 Identities = 58/123 (47%), Positives = 73/123 (59%), Gaps = 3/123 (2%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGT---GRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 P LN G +PVL LGT G+G +E AV AI AGYRHIDTA VY +E Sbjct: 3 PSVTLNTGALMPVLGLGTWKSGKGVTTE---------AVKVAIGAGYRHIDTAYVYENET 53 Query: 269 QVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 +VG G+ I +G+V RE+LFI +KLW H V ++L L LDYVDLYL+HFP Sbjct: 54 EVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFP 113 Query: 449 ISS 457 + + Sbjct: 114 MGA 116 Score = 21.4 bits (43), Expect(2) = 2e-20 Identities = 8/23 (34%), Positives = 11/23 (47%) Frame = +2 Query: 443 FPISSKADGSPDNIDYLETWEGM 511 FP+ D +L+TWE M Sbjct: 147 FPLDEHNQLICDGTSFLDTWEAM 169 >UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Griffithsia japonica|Rep: Mannose 6-phosphate reductase - Griffithsia japonica (Red alga) Length = 174 Score = 100 bits (239), Expect = 2e-20 Identities = 52/110 (47%), Positives = 73/110 (66%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L G K+P+ GT + + E++ QAV A+ AGYRHID AAVY +E VG I+ Sbjct: 8 LQSGAKMPLNGFGTWKASVEETE------QAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 +AI+ G+V REDLFIT+K+WN HA +VV + R+SL+ +DY DL+L+ Sbjct: 62 KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111 >UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 337 Score = 100 bits (239), Expect = 2e-20 Identities = 50/115 (43%), Positives = 72/115 (62%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G +IP + LGT + +E VR AV A+ AGY H+D AA Y +E +VG+ + EA Sbjct: 12 NGLRIPRVGLGTWKARPNE------VRDAVRDALGAGYAHVDCAAAYANESEVGEALREA 65 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 +G RED+F+T+KLWND+ V L +L LG+ Y+DLYLIH+P++ K Sbjct: 66 FERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWK 120 >UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 321 Score = 100 bits (239), Expect = 2e-20 Identities = 50/116 (43%), Positives = 74/116 (63%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LNDG +IP + LGT S+ +V A+ A++ GYRHID AA YG+E+ +G + Sbjct: 18 KLNDGNQIPSIGLGT-----YYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSL 72 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 E +G + RED+F T+KLWN H VV ++++ LG+ Y+DLYLIH+PI+ Sbjct: 73 KEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIA 128 >UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase); n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) - Homo sapiens (Human) Length = 326 Score = 100 bits (239), Expect = 2e-20 Identities = 53/117 (45%), Positives = 71/117 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+DG IP++ LGT + +S +V AI+ GYRHID A +Y +E +VG+ I Sbjct: 12 LSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 E IA+G V RED+F KLW H V PTL +L+ L LDYVDLY+I P++ K Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK 126 >UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7; cellular organisms|Rep: Prostaglandin f synthase, putative - Leishmania major Length = 279 Score = 99 bits (238), Expect = 3e-20 Identities = 56/131 (42%), Positives = 79/131 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++G ++P L +GT A + + + ++ WA+ AGYRH+DTA Y +E+ VGQGI+ Sbjct: 10 LSNGVQVPQLGIGTWE--AKDGNEVVNIK----WAVNAGYRHVDTAHYYKNEKGVGQGIS 63 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 E G V R D+F+TTKLWN H + +S Q LG++YVDLYLIH+P Sbjct: 64 EC---G-VPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP------- 112 Query: 470 SPDNIDYLETW 502 P N Y+ETW Sbjct: 113 GP-NRSYIETW 122 >UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon cuniculi Length = 301 Score = 99 bits (238), Expect = 3e-20 Identities = 56/124 (45%), Positives = 78/124 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G +IP + LGT G E+ +R A + GYRHIDTA +YG+E+ +G + Sbjct: 7 KLNNGKEIPTVGLGTW-GMEDEAVLEGAIRNA----LSLGYRHIDTAFIYGNEKMIGNIL 61 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + +G+V R+DLFIT+KLWN H G LR SL L +DYVDLYLIH+P++ D Sbjct: 62 KKLFDEGVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVT--FD 117 Query: 467 GSPD 478 +PD Sbjct: 118 PAPD 121 >UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 316 Score = 99.5 bits (237), Expect = 4e-20 Identities = 57/145 (39%), Positives = 82/145 (56%), Gaps = 12/145 (8%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN GY IP + LGT + E V A+ A+ AGYRHID A VY ++++VG+ + Sbjct: 6 KLNSGYSIPAIGLGTWQSKPGE------VAAAIKTAVAAGYRHIDCAHVYQNQKEVGEAL 59 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 E + +G V RE+LFIT+K+WN H+ + + L L L YVDL LIH+P A+ Sbjct: 60 KEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWP-QGYAE 118 Query: 467 GSP------------DNIDYLETWE 505 G+ ++DYLETW+ Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWK 143 >UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomycetales|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 277 Score = 99.1 bits (236), Expect = 5e-20 Identities = 55/125 (44%), Positives = 77/125 (61%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 +++ P LN+G ++P L G + ++ T AV A+EAGYR IDTAA+YG+E Sbjct: 2 SSKVPPIILNNGVEMPQLGFGVWQVPDDDAQT------AVALALEAGYRSIDTAAIYGNE 55 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 E G+ IA A GL REDLF+TTKLWN + S+ +LGL+Y+DLYLIH+ Sbjct: 56 EGTGRAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHW 111 Query: 446 PISSK 460 P+ +K Sbjct: 112 PMPAK 116 >UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep: Oxidoreductase - Lactobacillus acidophilus Length = 285 Score = 99.1 bits (236), Expect = 5e-20 Identities = 55/136 (40%), Positives = 77/136 (56%) Frame = +2 Query: 104 HQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQG 283 + LN+G KIP++ GT + E ++V A+ GYRHIDTA+ YG+E+ VG+ Sbjct: 10 YTLNNGVKIPIIGFGTWQTPDGEV-----AEESVLAALNCGYRHIDTASAYGNEDSVGR- 63 Query: 284 IAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 AI K + R +LFITTKLWN H + + +SL L LDY+D+YLIH+P S Sbjct: 64 ---AIQKSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSM 120 Query: 464 DGSPDNIDYLETWEGM 511 I+ E+W M Sbjct: 121 RDHWAEIN-AESWRAM 135 >UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 303 Score = 99.1 bits (236), Expect = 5e-20 Identities = 59/142 (41%), Positives = 83/142 (58%), Gaps = 8/142 (5%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G+ IP + LGT + T S+ A+ A+E GYR IDTA VY +E+ VGQ + Sbjct: 4 LNNGHSIPPIGLGTYKITGSDGVA------AIKSAVEFGYRLIDTAFVYNNEQVVGQALR 57 Query: 290 EAIAKGL-VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 E ++G + RED+FI +KL H V R SL+RLGLDYVDLYL+H P++++ Sbjct: 58 EIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDS 117 Query: 467 GS-------PDNIDYLETWEGM 511 G D + LETW+ + Sbjct: 118 GDGNDRSEIDDEVTPLETWKAL 139 >UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinobacteria (class)|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 276 Score = 98.7 bits (235), Expect = 7e-20 Identities = 64/141 (45%), Positives = 84/141 (59%), Gaps = 2/141 (1%) Frame = +2 Query: 89 AQAPCHQLNDGYKIPVLALGTGRGTASESDTLD--QVRQAVFWAIEAGYRHIDTAAVYGD 262 A +P +LNDG++IP + LGT LD QV AV A+E GYRHIDTA YG+ Sbjct: 2 ALSPVIELNDGHRIPQIGLGTW--------PLDDHQVAAAVVNAVEGGYRHIDTAVKYGN 53 Query: 263 EEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH 442 E+ VG GI + GL R +LFITTKL + + + V L SL+RLGLDYVDL LIH Sbjct: 54 EKGVGNGIRSS---GL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIH 109 Query: 443 FPISSKADGSPDNIDYLETWE 505 +P+ P +++ TW+ Sbjct: 110 WPL-------PRRDEFISTWK 123 >UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep: Aldehyde reductase - Salinibacter ruber (strain DSM 13855) Length = 321 Score = 98.3 bits (234), Expect = 9e-20 Identities = 51/142 (35%), Positives = 84/142 (59%), Gaps = 10/142 (7%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G ++P++ LGT + E V +AV A+EAGYRH+D A +Y +E +VG ++++ Sbjct: 8 NGDEMPMIGLGTWKSPPGE------VYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDS 61 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD--- 466 G + R+D+++T+KLWN+ H V P L ++L L LD +DLYLIH+P++ + + Sbjct: 62 FDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVDF 121 Query: 467 -------GSPDNIDYLETWEGM 511 SP+ + ETW M Sbjct: 122 PESPDDFVSPEAVPLTETWAAM 143 >UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several dehydrogenases of different specificities; n=4; Pezizomycotina|Rep: Similarity: shows similarity to several dehydrogenases of different specificities - Aspergillus niger Length = 381 Score = 98.3 bits (234), Expect = 9e-20 Identities = 53/117 (45%), Positives = 71/117 (60%), Gaps = 2/117 (1%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN G +IP L GT + QV AV+ A++AGYRH+D A +Y ++ +V +GI Sbjct: 9 LNSGAQIPQLGFGTWQSAPG------QVGDAVYEALKAGYRHLDLATIYQNQREVAEGIK 62 Query: 290 EAI--AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 A GL RED+FIT+KLWN +H V L E L L LDY+DLYL+H+P+S Sbjct: 63 RAYKDVPGL-KREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVS 118 >UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep: Aldo/keto reductase - Kineococcus radiotolerans SRS30216 Length = 343 Score = 97.9 bits (233), Expect = 1e-19 Identities = 50/123 (40%), Positives = 75/123 (60%) Frame = +2 Query: 80 VSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYG 259 V A P +L G +P + +GT S+ + +V AV A+ AGYR +D AAVYG Sbjct: 8 VDPALVPRRELRGGATVPAIGIGT---FGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYG 64 Query: 260 DEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 +E QVG+ +A A+A G V R++LF+ +K+WND HA V ++ SL+ L LD++D + Sbjct: 65 NEAQVGEALAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFV 123 Query: 440 HFP 448 H+P Sbjct: 124 HWP 126 >UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose reductase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to aldose reductase - Strongylocentrotus purpuratus Length = 274 Score = 97.5 bits (232), Expect = 2e-19 Identities = 47/92 (51%), Positives = 62/92 (67%) Frame = +2 Query: 188 QVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHAR 367 QV AV AI+ GYRHID A VYG+E +VG G+ E +V RED+FIT+KLWN+KH Sbjct: 11 QVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHP 70 Query: 368 GQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 V +L+ L L YVDLYL+H+P++ +A Sbjct: 71 DDVEQACDITLKNLQLSYVDLYLMHWPMAYQA 102 >UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Orconectes limosus|Rep: Aldoketoreductase-like protein - Orconectes limosus (Spinycheek crayfish) Length = 336 Score = 97.5 bits (232), Expect = 2e-19 Identities = 52/117 (44%), Positives = 70/117 (59%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P LN G IPV+ LGTG + + + V + A+E GYRH D+AA YG+E +G Sbjct: 12 PTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNEAIIG 71 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 Q + I++G V RE+LFITTKL + V L++SL L L YVDLYL+H+P Sbjct: 72 QVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHYP 128 >UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus (Mouse) Length = 316 Score = 97.1 bits (231), Expect = 2e-19 Identities = 51/110 (46%), Positives = 70/110 (63%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G K+P++ LGT + ++ VR+AV AI+AGYRHID A VY +E +VG+ I E I Sbjct: 10 GAKMPIVGLGTWKSPPAK------VREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKI 63 Query: 299 AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + V REDLFI +KLW+ + V + +L L LDY+DLYLIH+P Sbjct: 64 QEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWP 113 >UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 97.1 bits (231), Expect = 2e-19 Identities = 53/121 (43%), Positives = 73/121 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+DGYKIP G G E T +QAV WA+E GYR IDTAA Y +E++VG Sbjct: 9 LSDGYKIP--RFGLGLYDLDEKHT----KQAVLWALENGYRMIDTAASYNNEKRVG---- 58 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 EA+ + V R ++++ TK+++ H + + SL LG+DYVDLYLIHFP+ + G Sbjct: 59 EALRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPVPAGVVG 118 Query: 470 S 472 S Sbjct: 119 S 119 >UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Saccharomycetales|Rep: D-arabinose dehydrogenase - Pichia stipitis (Yeast) Length = 326 Score = 97.1 bits (231), Expect = 2e-19 Identities = 52/119 (43%), Positives = 73/119 (61%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++G IP L LGT + ++++ V A++AGYRHIDTA YG EE +GQ + Sbjct: 12 LSNGKTIPALGLGT-----VPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALK 66 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + +G+V REDLFITTK+W + +L +SL LGLDYVDL+L H+P+ D Sbjct: 67 QLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGD 123 >UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1; Arabidopsis thaliana|Rep: Uncharacterized protein At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 283 Score = 96.7 bits (230), Expect = 3e-19 Identities = 56/141 (39%), Positives = 78/141 (55%), Gaps = 6/141 (4%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G K P + LGT + + V AV A++ GYRHID A +YG+E+++G + Sbjct: 9 KLNTGAKFPSVGLGTWQASPG------LVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + +V REDLFIT+KLW H V L +L+ L L+YVDLYLIH+P K Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122 Query: 467 G---SPDN---IDYLETWEGM 511 P+N +D TW+ M Sbjct: 123 SVGIKPENLLPVDIPSTWKAM 143 >UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis thaliana (Mouse-ear cress) Length = 315 Score = 96.7 bits (230), Expect = 3e-19 Identities = 56/141 (39%), Positives = 78/141 (55%), Gaps = 6/141 (4%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G K P + LGT + + V AV A++ GYRHID A +YG+E+++G + Sbjct: 9 KLNTGAKFPSVGLGTWQASPG------LVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + +V REDLFIT+KLW H V L +L+ L L+YVDLYLIH+P K Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKG 122 Query: 467 G---SPDN---IDYLETWEGM 511 P+N +D TW+ M Sbjct: 123 SVGIKPENLLPVDIPSTWKAM 143 >UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase family 1 member C-like protein 2 - Homo sapiens (Human) Length = 320 Score = 93.9 bits (223), Expect(2) = 3e-19 Identities = 49/101 (48%), Positives = 64/101 (63%) Frame = +2 Query: 158 GTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFIT 337 G +S + +V +AV AI+AGYRH D A Y +E +VG GI I +G V REDLFI Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67 Query: 338 TKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 TKLW H + V R+SL+ L L+Y+DLYLIH+P+ K Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108 Score = 23.4 bits (48), Expect(2) = 3e-19 Identities = 7/13 (53%), Positives = 10/13 (76%) Frame = +2 Query: 473 PDNIDYLETWEGM 511 P + D+L+TWE M Sbjct: 143 PSDTDFLDTWEAM 155 >UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens (Human) Length = 263 Score = 93.9 bits (223), Expect(2) = 3e-19 Identities = 49/101 (48%), Positives = 64/101 (63%) Frame = +2 Query: 158 GTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFIT 337 G +S + +V +AV AI+AGYRH D A Y +E +VG GI I +G V REDLFI Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67 Query: 338 TKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 TKLW H + V R+SL+ L L+Y+DLYLIH+P+ K Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFK 108 Score = 23.4 bits (48), Expect(2) = 3e-19 Identities = 7/13 (53%), Positives = 10/13 (76%) Frame = +2 Query: 473 PDNIDYLETWEGM 511 P + D+L+TWE M Sbjct: 143 PSDTDFLDTWEAM 155 >UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Lin2739 protein - Listeria innocua Length = 283 Score = 96.3 bits (229), Expect = 4e-19 Identities = 56/114 (49%), Positives = 75/114 (65%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G ++P+L GT + T + + QAV AI AGYRHIDTA Y +EE VG+GI Sbjct: 5 KLNNGIEVPILGFGTYQITDA-----GEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGI 59 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 A A G V R++LFITTK+W + + V+ + SL+RLGLDY+DL LIH P Sbjct: 60 A---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP 109 >UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Photorhabdus luminescens subsp. laumondii Length = 292 Score = 96.3 bits (229), Expect = 4e-19 Identities = 53/117 (45%), Positives = 74/117 (63%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +L DG +P L LG+ AS+ Q+ + + A++ GYR IDTAA+Y +E+ VG Sbjct: 5 PIIRLADGNHMPQLGLGSW---ASDDQ---QIAETIHAALDIGYRAIDTAAIYNNEKGVG 58 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + E + RED+F+TTKLWND+H + L ESL++L LDYVDLYLIH+P Sbjct: 59 NALQETD----IPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWP 109 >UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomycetaceae|Rep: Glycerol dehydrogenase - Zygosaccharomyces rouxii (Candida mogii) Length = 310 Score = 95.9 bits (228), Expect = 5e-19 Identities = 56/124 (45%), Positives = 76/124 (61%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G IP + LGT R +E +AV A++AGYRHID AAVYG+E +VG+ I Sbjct: 12 KLNTGQTIPQVGLGTWRSKENEG------YKAVIEALKAGYRHIDGAAVYGNEGEVGKAI 65 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 ++ G V R ++F+TTKLW Q L +SLQRLGLDYV LYL+H+P+ + + Sbjct: 66 QDS---G-VPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRTE 119 Query: 467 GSPD 478 D Sbjct: 120 NIKD 123 >UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lmo2592 protein - Listeria monocytogenes Length = 283 Score = 95.5 bits (227), Expect = 6e-19 Identities = 56/116 (48%), Positives = 76/116 (65%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G ++P+L GT + T + + AV AI+AGYRHIDTA Y +EE VG+GI Sbjct: 5 KLNNGVEVPILGFGTYQITDAA-----EAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGI 59 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 A A G V R++LFITTK+W + + V+ + SL+RLGLDYVDL LIH P + Sbjct: 60 A---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN 111 >UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto reductase family - Enterococcus faecalis (Streptococcus faecalis) Length = 279 Score = 95.5 bits (227), Expect = 6e-19 Identities = 54/142 (38%), Positives = 79/142 (55%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 T+ A LN+G KIP + LG + + +T V + + GYR IDTA +YG+E Sbjct: 3 TSLADTVTLNNGTKIPGMGLGVFQ--IPDEETAKVVEEGII----NGYRLIDTAQIYGNE 56 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 G GI +A + REDLF+T+K+WN + + + +SL+RLGLDY+DLYLIH+ Sbjct: 57 SGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHW 116 Query: 446 PISSKADGSPDNIDYLETWEGM 511 P N Y E+W+ + Sbjct: 117 ---------PGNNSYKESWQAL 129 >UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|Rep: Reductase AKOR2 - Pleurotus djamor Length = 306 Score = 95.1 bits (226), Expect = 8e-19 Identities = 54/114 (47%), Positives = 74/114 (64%), Gaps = 1/114 (0%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN G ++P LALG G E T Q ++ A+++GYRHIDTA +Y E+ VG I Sbjct: 9 LNTGARMPALALGGWAGLTEEERT--QAKEWFLTALKSGYRHIDTAQIYYTEKSVGNAIR 66 Query: 290 EAIAKGLVTREDLFITTKL-WNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 E+ G + RE+LFITTKL WN H+R V + ++SL+ LG +Y+DLYL+HFP Sbjct: 67 ES---G-IPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113 >UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep: Oxidoreductase - Xanthomonas campestris pv. campestris (strain 8004) Length = 267 Score = 94.7 bits (225), Expect = 1e-18 Identities = 58/123 (47%), Positives = 77/123 (62%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 +P LGT R + +D VR A + GYR IDTA +Y +E QVGQ IA+A G Sbjct: 3 VPAFGLGTFR--LKDQVVIDSVRNA----LALGYRAIDTAQIYDNEAQVGQAIADA---G 53 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNID 487 V R+ LF+TTK+W D+ +R + P+L+ESL++LG DYVDL LIH+P S D P + Sbjct: 54 -VPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP--SPKDQVPMR-E 109 Query: 488 YLE 496 YLE Sbjct: 110 YLE 112 >UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Yersinia pestis Length = 277 Score = 94.7 bits (225), Expect = 1e-18 Identities = 55/117 (47%), Positives = 71/117 (60%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +L DG +P L LG + + E++ AV A+E GYR IDTAA+Y +EE Sbjct: 5 PLIKLYDGRLMPQLGLGVWQASIQETEL------AVSKALEVGYRSIDTAAIYKNEE--- 55 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 G+ +A+ V R++LFITTKLWND Q L SLQ+L LDYVDLYLIH+P Sbjct: 56 -GVGKALKAAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP 109 >UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep: Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 94.3 bits (224), Expect = 1e-18 Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 11/111 (9%) Frame = +2 Query: 212 AIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLR 391 AI AGYRHIDTA Y +E VG I I +G++ R+D+FI +KLW HA + Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68 Query: 392 ESLQRLGLDYVDLYLIHFPISSKADGS---PD--------NIDYLETWEGM 511 +SL L LDY+D YL+HFP+ K G P+ +IDY++ W GM Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGM 119 >UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase A - Escherichia coli (strain UTI89 / UPEC) Length = 294 Score = 94.3 bits (224), Expect = 1e-18 Identities = 50/112 (44%), Positives = 72/112 (64%), Gaps = 1/112 (0%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++ K+P++ G + T D +Q+V AI GYR IDTAAVYG+E+ VG+ + Sbjct: 11 LSNNLKMPMMGFGVFQVTDK-----DVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVR 65 Query: 290 EAIAKGLVTREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIH 442 EAI++GL TRE+LFIT+KLW D + + SL++ GL+Y DLYL+H Sbjct: 66 EAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH 117 >UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: Aldehyde reductase - Acidobacteria bacterium (strain Ellin345) Length = 313 Score = 94.3 bits (224), Expect = 1e-18 Identities = 49/116 (42%), Positives = 65/116 (56%) Frame = +2 Query: 140 ALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTR 319 ALG G A + T+ R A + AG+RH D A Y +E +VG+ + A G + R Sbjct: 22 ALGFGTLIADPALTITATRDA----LAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAR 77 Query: 320 EDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNID 487 E++F+TTKLWN H +V P SL RLGLDY+DLYLIH P + + D D Sbjct: 78 EEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRD 133 >UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 700755|Rep: YvgN - Psychroflexus torquis ATCC 700755 Length = 280 Score = 93.9 bits (223), Expect = 2e-18 Identities = 56/136 (41%), Positives = 83/136 (61%), Gaps = 2/136 (1%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LNDG +IP++ GT + A+E + + ++++ A+ GYR IDT A+Y +EE VG+ I Sbjct: 5 LNDGNRIPIVGFGTYK--ANEEEGIKSIQKS---ALTLGYRLIDTVAIYQNEEAVGKAIK 59 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS--SKA 463 A+G V RE++F+TTKLW + Q L ESL++L L+Y+DLYLIH+P + + Sbjct: 60 ---ARG-VLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYK 115 Query: 464 DGSPDNIDYLETWEGM 511 D N D TW M Sbjct: 116 DWQKTNAD---TWRAM 128 >UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative aldo-keto reductase/oxidase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 274 Score = 93.9 bits (223), Expect = 2e-18 Identities = 49/99 (49%), Positives = 68/99 (68%) Frame = +2 Query: 152 GRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLF 331 G GT + S D+ Q V WA+EAG RHIDTA YG+E+ V +GI +A G V R ++F Sbjct: 14 GYGTWNRS--ADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIKDA---G-VARNEIF 67 Query: 332 ITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 ITTK+ D + G V+P++RESL++L +D VDL L+H+P Sbjct: 68 ITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLLHWP 106 >UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=10; Trichomonas vaginalis|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 312 Score = 93.9 bits (223), Expect = 2e-18 Identities = 49/105 (46%), Positives = 68/105 (64%), Gaps = 1/105 (0%) Frame = +2 Query: 152 GRGTASESDTLDQVRQAVFWAIE-AGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDL 328 G GT +D +++ A+ +AIE G RHIDTA Y ++ +G+ + E AKG + RED+ Sbjct: 7 GFGTYLANDPA-KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKREDM 65 Query: 329 FITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 FITTKLW H + V P L E+L +L L YVDL+LIH PI+ K+ Sbjct: 66 FITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKS 110 >UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - Trichoderma atroviride (Hypocrea atroviridis) Length = 327 Score = 93.9 bits (223), Expect = 2e-18 Identities = 49/129 (37%), Positives = 77/129 (59%), Gaps = 1/129 (0%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVY 256 S T + + LN G KIP + GT ++ +T AV A++ GYRH+D A Y Sbjct: 6 SQKTLSSTTYTLNTGAKIPAVGFGTFANEGAKGETY----AAVTKALDVGYRHLDCAWFY 61 Query: 257 GDEEQVGQGIAEAIAKGL-VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLY 433 +E++VG I + +A+ VTR+DLFI TK+WN H V + + S + L +DY+DL+ Sbjct: 62 LNEDEVGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLF 121 Query: 434 LIHFPISSK 460 L+H+PI+++ Sbjct: 122 LVHWPIAAE 130 >UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 292 Score = 93.5 bits (222), Expect = 3e-18 Identities = 54/129 (41%), Positives = 75/129 (58%) Frame = +2 Query: 83 STAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGD 262 +++ P L G IPVL GT + + DT D V +A +E GYRHIDTA +YG+ Sbjct: 12 ASSPIPTFMLPTGSPIPVLGFGTYK--VAPEDTYDAVSRA----LEVGYRHIDTAQMYGN 65 Query: 263 EEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH 442 E +VG + A G + REDLFITTK+ N H + ++R SL+ L DYVDL L+H Sbjct: 66 EAEVGAALE---ASG-IAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVH 121 Query: 443 FPISSKADG 469 +P+ + G Sbjct: 122 WPLPTLYGG 130 >UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; Trypanosomatidae|Rep: Aldo-keto reductase-like protein - Leishmania major strain Friedlin Length = 372 Score = 93.5 bits (222), Expect = 3e-18 Identities = 48/114 (42%), Positives = 65/114 (57%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 + D + IP L GT R SE+ AV +A+ GYRH+D A YG+E VG+ +A Sbjct: 24 MRDSHTIPQLGFGTYRLPVSEAT------DAVAFALSCGYRHVDCAKAYGNEAAVGEALA 77 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 +A+ REDLF+T+KLW V R +L L LDY+DLYLIH+P+ Sbjct: 78 QALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPV 131 >UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 286 Score = 93.1 bits (221), Expect = 3e-18 Identities = 50/119 (42%), Positives = 72/119 (60%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 Q P LN+G ++P+L G + +++ + V+ AI+ GYR IDTAA Y +EE Sbjct: 2 QVPKVTLNNGVEMPILGYGVFQIPPEKTE------ECVYEAIKVGYRLIDTAASYMNEEG 55 Query: 272 VGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 VG+ I AI +G+V RE+LF+TTKLW +SL++L L+Y+DLYLIH P Sbjct: 56 VGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114 >UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase; n=2; Parasitella parasitica|Rep: 4-dihydromethyltrisporate dehydrogenase - Parasitella parasitica Length = 321 Score = 93.1 bits (221), Expect = 3e-18 Identities = 44/83 (53%), Positives = 57/83 (68%) Frame = +2 Query: 203 VFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVP 382 ++ AI+ GYR D A YG+E +VG+GI +AI +GLV RE+LFI TKLWN H++ V Sbjct: 34 IYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSKQHVRT 93 Query: 383 TLRESLQRLGLDYVDLYLIHFPI 451 L+ GL+Y DLYLIHFPI Sbjct: 94 AFDRQLKDWGLEYFDLYLIHFPI 116 >UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 322 Score = 93.1 bits (221), Expect = 3e-18 Identities = 47/114 (41%), Positives = 71/114 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G +IP +ALG + S A WA +AGYRHID+AA Y +EE VG+ + Sbjct: 20 KLNNGQEIPQVALGVYKAPNDGS-----TENACKWAFDAGYRHIDSAARYMNEESVGRAL 74 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 AE + V R ++FIT+KLW+ H + + +SL++L +DY+D+YL+H P Sbjct: 75 AEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSP 126 >UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaster|Rep: CG40064-PA - Drosophila melanogaster (Fruit fly) Length = 361 Score = 92.7 bits (220), Expect = 4e-18 Identities = 49/120 (40%), Positives = 67/120 (55%), Gaps = 12/120 (10%) Frame = +2 Query: 188 QVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHAR 367 Q AV AIE G+RH DTA Y +E+++G+ + I G ++RE++F+TTKLWN H Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104 Query: 368 GQVVPTLRESLQRLGLDYVDLYLIHFPISSK-------ADGSPD-----NIDYLETWEGM 511 V + L+ LG Y+DLYL+HFP+ K S D IDYL+TW M Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAM 164 >UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2; Ascomycota|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 323 Score = 91.9 bits (218), Expect = 8e-18 Identities = 51/116 (43%), Positives = 67/116 (57%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN GY IP + LGT E V AV A+ AGYRHID AA Y +E +VG G Sbjct: 8 KLNSGYNIPAIGLGTWLSKPHE------VENAVEAALRAGYRHIDAAACYQNENEVGNGW 61 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 K V R+ +FIT+KLWN H V + ++L+ L DY+DLYLIH+P++ Sbjct: 62 K----KSGVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVA 113 >UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas putida Length = 296 Score = 91.9 bits (218), Expect = 8e-18 Identities = 53/119 (44%), Positives = 74/119 (62%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 ++P LN+G K+P L LG +A E+ + A+ AI +GYR IDTA Y +E Q Sbjct: 4 KSPLINLNNGVKMPALGLGVFAASAEETAS------AIASAISSGYRLIDTARSYNNEAQ 57 Query: 272 VGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 VG+GI + G V R ++F+TTKL+N + + + ESL RLGLDYVDLYL+H+P Sbjct: 58 VGEGIRNS---G-VDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112 >UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Propionibacterium freudenreichii subsp. shermanii|Rep: Putative aldo-keto reductase - Propionibacterium freudenreichii subsp. shermanii Length = 280 Score = 91.5 bits (217), Expect = 1e-17 Identities = 56/144 (38%), Positives = 79/144 (54%) Frame = +2 Query: 80 VSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYG 259 + T P +L+ G ++P+L +GT E R AV AIE GYR +DTA YG Sbjct: 3 IPTTPTPTVELSGGTRMPMLGMGTWPLKGEEC------RAAVASAIEQGYRLVDTAEAYG 56 Query: 260 DEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 +EE VG+ + EA R ++F+TTK H+R V L SL+RLGLDYVDL+L+ Sbjct: 57 NEEAVGKAVREAGPD----RAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLM 112 Query: 440 HFPISSKADGSPDNIDYLETWEGM 511 H+P+ P Y++ + GM Sbjct: 113 HWPM-------PGEGSYVDAYRGM 129 >UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; Bacteria|Rep: 2,5-didehydrogluconate reductase - Opitutaceae bacterium TAV2 Length = 334 Score = 91.5 bits (217), Expect = 1e-17 Identities = 59/138 (42%), Positives = 77/138 (55%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P L+DG IP L LG + D QA F AGYR IDTA +YG+EE VG Sbjct: 60 PTLPLSDGTSIPQLGLGVWQ---MPDDGAGVPIQAAF---NAGYRAIDTAPIYGNEEGVG 113 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 + I A GL R++L+ITTK+WN + +RESL RL L+YVDLYLIH+P+ Sbjct: 114 RAIR---ASGL-PRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV-- 167 Query: 458 KADGSPDNIDYLETWEGM 511 P Y++TW+ + Sbjct: 168 -----PKIDRYVDTWKAL 180 >UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 295 Score = 91.1 bits (216), Expect = 1e-17 Identities = 48/120 (40%), Positives = 76/120 (63%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L +G K+PV LGT + S+ + + +R A ++ GYRHIDTA +Y +E+Q+G + Sbjct: 9 ELCNGSKLPVFGLGTYK-VVSKEEMVTFLRTA----LDLGYRHIDTAIMYENEKQIGDAL 63 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 E +G REDLF+ TKL+++K+ + V +R+SLQ L +Y+DLYL+H+ S D Sbjct: 64 QEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121 >UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 263 Score = 91.1 bits (216), Expect = 1e-17 Identities = 48/100 (48%), Positives = 65/100 (65%) Frame = +2 Query: 152 GRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLF 331 G G +D ++ A+ A++ GYR +DTA+ Y +EE VG GIA+ G V R+DLF Sbjct: 5 GLGLYKTTDAVE-AEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---G-VPRKDLF 59 Query: 332 ITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 ITTK+WN+ G V + SL RLGLDY+DLYLIH+P+ Sbjct: 60 ITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV 99 >UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Dikarya|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 353 Score = 91.1 bits (216), Expect = 1e-17 Identities = 53/122 (43%), Positives = 76/122 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G IP + LGT + A E VRQAV A++AGYRHID A Y +E++VG GI Sbjct: 40 KLNTGASIPAIGLGTWQAKAGE------VRQAVAHALKAGYRHIDGALCYQNEDEVGLGI 93 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 ++ G V R ++F+T+K+W+ H R V L +L+ L DY+DLYLIH+P+ + Sbjct: 94 KDS---G-VPRSEIFLTSKVWSSYHDR--VEECLDTTLKSLQTDYLDLYLIHWPVRLAPN 147 Query: 467 GS 472 G+ Sbjct: 148 GT 149 >UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; Saccharomycetales|Rep: Probable oxidoreductase YJR096W - Saccharomyces cerevisiae (Baker's yeast) Length = 282 Score = 91.1 bits (216), Expect = 1e-17 Identities = 54/139 (38%), Positives = 82/139 (58%), Gaps = 3/139 (2%) Frame = +2 Query: 104 HQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQG 283 ++L++G+KIP +ALGT S Q + V+ ++ GYRH DTA +YG+E++VG G Sbjct: 6 YKLSNGFKIPSIALGTYDIPRS------QTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDG 59 Query: 284 IAEAIAK--GLVTREDLFITTKLWNDKHARGQVVPTLRESLQRL-GLDYVDLYLIHFPIS 454 I + + + G RE++F TTKLWN ++ + +R+ L + GL Y+DL LIH P+ Sbjct: 60 IIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL- 118 Query: 455 SKADGSPDNIDYLETWEGM 511 +GS LETW M Sbjct: 119 ---EGSKLR---LETWRAM 131 >UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; Parvularcula bermudensis HTCC2503|Rep: Putative uncharacterized protein - Parvularcula bermudensis HTCC2503 Length = 278 Score = 90.6 bits (215), Expect = 2e-17 Identities = 48/108 (44%), Positives = 69/108 (63%) Frame = +2 Query: 131 PVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGL 310 P+ LG G D R A IE GYRHID AA+Y +E++VG+GI ++ G Sbjct: 10 PIPRLGFGTWQLEGEDARTSTRTA----IETGYRHIDGAAIYKNEKKVGEGIKDS---G- 61 Query: 311 VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 + R++LF+TTK+WN+ +G+ + ESL RLGLDYV+L L+H+PI+ Sbjct: 62 IPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPIN 109 >UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=3; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 309 Score = 90.6 bits (215), Expect = 2e-17 Identities = 52/134 (38%), Positives = 80/134 (59%), Gaps = 14/134 (10%) Frame = +2 Query: 152 GRGTASESDTLDQVRQAVFWAIE-AGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDL 328 G GT D ++ AV AIE +GYRH+D AA Y ++E +G+ ++E AKG V RE++ Sbjct: 8 GLGTFLAEDPA-ALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEV 66 Query: 329 FITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF--PISSKADGS---------- 472 +IT+K+WN KH +V ++++L+ L L+Y+DL L+H+ S+ D Sbjct: 67 WITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKI 126 Query: 473 -PDNIDYLETWEGM 511 +NID LETW+ M Sbjct: 127 ITENIDILETWKAM 140 >UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 289 Score = 90.2 bits (214), Expect = 2e-17 Identities = 56/146 (38%), Positives = 77/146 (52%), Gaps = 1/146 (0%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAI-EAGYRHIDTAAV 253 S + P L++G IP+L LGT +AV +A+ E G RHIDTA Sbjct: 7 SCTALSCPAVPLHNGLNIPILGLGTSHYGGYS-------HEAVLYALQECGIRHIDTAKR 59 Query: 254 YGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLY 433 YG EE +G+ + E+ G V RE+L++TTKLW + R+S RLG+DY+DLY Sbjct: 60 YGCEEALGKAVTES---G-VQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLY 115 Query: 434 LIHFPISSKADGSPDNIDYLETWEGM 511 L+H+P S G LETW + Sbjct: 116 LMHWP-DSMVPGRSSQEVRLETWRAL 140 >UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Staphylococcus|Rep: Oxidoreductase, aldo/keto reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 279 Score = 90.2 bits (214), Expect = 2e-17 Identities = 49/113 (43%), Positives = 69/113 (61%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+GY +P + LG + A E Q+ + V A++AGYR DTA YG+E+ +G Sbjct: 8 LNNGYPMPAVGLGVYK-IADE-----QMEEVVRTALDAGYRAFDTAYFYGNEKALGS--- 58 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 A+ V R++LFIT+KLWND Q + +SL LGLDY+DL+LIH+P Sbjct: 59 -ALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP 110 >UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: Aldehyde reductase - Lactobacillus acidophilus Length = 278 Score = 90.2 bits (214), Expect = 2e-17 Identities = 48/113 (42%), Positives = 68/113 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G K+P L G + D L Q +Q V +E GYR +DTA +YG+E+ VG Sbjct: 7 LNNGIKMPRLGFGV-----YQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG---- 57 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 +AI V RED+FIT+K+W D + + +S+++L LDY+DLYLIH P Sbjct: 58 DAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP 110 >UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; Bacteria|Rep: 2,5-didehydrogluconate reductase - Exiguobacterium sibiricum 255-15 Length = 274 Score = 90.2 bits (214), Expect = 2e-17 Identities = 51/134 (38%), Positives = 77/134 (57%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G +P L G + E + + VR+A + GYR IDTA +Y +E VG+ + Sbjct: 6 LNNGLVMPQLGYGVFK--VPEQEVYEAVREA----LRVGYRSIDTAMIYENEAGVGRALK 59 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 ++ G + RED+F+TTK+WN + + SLQ+LG+DYVDLYLIH+P+ Sbjct: 60 DS---G-IPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM------ 109 Query: 470 SPDNIDYLETWEGM 511 PD Y++TW + Sbjct: 110 -PDEDLYMDTWRAL 122 >UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1; Saccharopolyspora erythraea NRRL 2338|Rep: 2,5-diketo-D-gluconic acid reductase - Saccharopolyspora erythraea (strain NRRL 23338) Length = 159 Score = 90.2 bits (214), Expect = 2e-17 Identities = 56/127 (44%), Positives = 75/127 (59%), Gaps = 1/127 (0%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P LN+G ++P LG G E D+ AV A+EAGYR IDTAA YG+E VG Sbjct: 5 PTVTLNNGVEMP--QLGYGVFQVPE----DETAAAVGAALEAGYRSIDTAAAYGNEAAVG 58 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP-IS 454 + +A GL R++LF+TTKLWN + SL+ LGLD++DLYLIH+P +S Sbjct: 59 RALA---GSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWPTLS 114 Query: 455 SKADGSP 475 + + G P Sbjct: 115 AVSTGRP 121 >UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2; Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid reductase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 283 Score = 89.4 bits (212), Expect = 4e-17 Identities = 56/136 (41%), Positives = 73/136 (53%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P L DG IP LGT +E+ ++ Q AIE GYRHIDTA++Y +E +VG Sbjct: 10 PSVLLGDGVSIPQFGLGTYELPPNEASSVVQS------AIELGYRHIDTASLYANEREVG 63 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 + AIA + RE+ F+TTKLWN + + SL L LDYVDLYLIH+P Sbjct: 64 R----AIASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP--- 114 Query: 458 KADGSPDNIDYLETWE 505 P + Y+ WE Sbjct: 115 ----CPPSELYINVWE 126 >UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales bacterium HTCC2654 Length = 278 Score = 89.0 bits (211), Expect = 5e-17 Identities = 59/139 (42%), Positives = 80/139 (57%) Frame = +2 Query: 95 APCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQV 274 AP L +G ++P L LGT T D+ +AV AIE GYR IDTA Y +E V Sbjct: 7 APTVTLANGVEMPQLGLGTWPMTD------DEAAKAVATAIETGYRLIDTAENYKNETGV 60 Query: 275 GQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 GQGI +A G V R+++F+TTK+ H+ SL+RLGLDY+DL+LIH+P Sbjct: 61 GQGIRDA---G-VARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP-- 114 Query: 455 SKADGSPDNIDYLETWEGM 511 +PD Y+E +EG+ Sbjct: 115 -----NPDQGTYVEAFEGL 128 >UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03517.1 - Gibberella zeae PH-1 Length = 364 Score = 88.6 bits (210), Expect = 7e-17 Identities = 54/151 (35%), Positives = 86/151 (56%), Gaps = 6/151 (3%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYK-IPVLALGT---GRGTASESDTLDQVRQAVFWAIEAGYRHIDT 244 S A+ P N+ + IP LGT G+G V AV +A++ GYRHIDT Sbjct: 42 SFGPAEMPEFNKNETVRDIPAFGLGTWLAGKGV---------VVPAVEYALKGGYRHIDT 92 Query: 245 AAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYV 424 A ++ +E++VG+GI A G V+R+++++T KLWN H V + S+ LG++Y+ Sbjct: 93 ALIWRNEDEVGKGIK---ASG-VSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYL 148 Query: 425 DLYLIHFPIS--SKADGSPDNIDYLETWEGM 511 DLYLIH+P++ + +N ++TW+ M Sbjct: 149 DLYLIHYPVAWVPETRDVDNNTSLIDTWKAM 179 >UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA15457-PA - Nasonia vitripennis Length = 388 Score = 88.2 bits (209), Expect = 9e-17 Identities = 58/147 (39%), Positives = 86/147 (58%), Gaps = 12/147 (8%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L+ G++IP + LGT + LD++ A+ A+E GYRHIDTA Y +E +G+ + Sbjct: 27 KLSSGHEIPAVGLGTS------TIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKIL 80 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP------ 448 + KG RED+FIT+KL + + V L+ SL+ LGLDYVD+YLIH P Sbjct: 81 KKWFDKG-GKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEG 139 Query: 449 --ISSK--ADGSP--DNIDYLETWEGM 511 +SSK DG+ D++D+ W+ M Sbjct: 140 ENLSSKQDKDGNDLFDDVDHKALWKAM 166 >UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6; Pezizomycotina|Rep: Aldo/keto reductase family proteins - Aspergillus oryzae Length = 294 Score = 88.2 bits (209), Expect = 9e-17 Identities = 53/134 (39%), Positives = 77/134 (57%), Gaps = 3/134 (2%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYKIPVLALGTGRG---TASESDTLDQVRQAVFWAIEAGYRHIDTA 247 S S P +LND IP+L GTG A + ++ +A+ AI GYRH+D A Sbjct: 3 SNSIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGA 62 Query: 248 AVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVD 427 VYG E ++G I E+ G + RE+LF+TTK+ + + + +SL++L L+YVD Sbjct: 63 EVYGTEAELGVAIKES---G-IPREELFVTTKVITNI---ADIPSAIDQSLRKLQLNYVD 115 Query: 428 LYLIHFPISSKADG 469 LYLIH P +K+DG Sbjct: 116 LYLIHSPFFAKSDG 129 >UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A; n=1; Rhodobacterales bacterium HTCC2150|Rep: 2,5-diketo-D-gluconic acid reductase A - Rhodobacterales bacterium HTCC2150 Length = 334 Score = 87.8 bits (208), Expect = 1e-16 Identities = 48/95 (50%), Positives = 58/95 (61%), Gaps = 7/95 (7%) Frame = +2 Query: 185 DQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHA 364 D + + AI+AGYRHIDTA+ Y +E+ VG GI + +TR+DLF+T KLW A Sbjct: 61 DDAKSTISAAIQAGYRHIDTASGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPA 120 Query: 365 RGQV----VPTLRE---SLQRLGLDYVDLYLIHFP 448 G TL E SL RLGLDYVDLYLIH P Sbjct: 121 WGDAPKTKAQTLDECDASLARLGLDYVDLYLIHAP 155 >UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid reductase B - Yersinia pestis Length = 267 Score = 87.8 bits (208), Expect = 1e-16 Identities = 50/107 (46%), Positives = 69/107 (64%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 IPV LGT R + +D V QA + GYR IDTA +Y +E VGQ I E+ G Sbjct: 3 IPVFGLGTFR--LQDQIVIDSVSQA----LTLGYRAIDTAQIYENEAPVGQAIQES---G 53 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + R++LFITTK+W ++ +++P+LRES+Q+L DYVDL LIH+P Sbjct: 54 -INRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99 >UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis alexandrii HTCC2633 Length = 275 Score = 87.4 bits (207), Expect = 2e-16 Identities = 47/112 (41%), Positives = 67/112 (59%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G IP L GT + + D + V A++ GYRHIDTA +YG+E VG G ++ Sbjct: 8 NGADIPKLGFGTWQ--LEDEDAA----RGVATALKTGYRHIDTAQIYGNEAAVGDGWKQS 61 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 K RED F+TTK+W DK G + +++ESL +L DYVDL L+H+P+ Sbjct: 62 GVK----REDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV 109 >UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10; Pezizomycotina|Rep: Related to aldo-keto reductase YPR1 - Neurospora crassa Length = 322 Score = 87.4 bits (207), Expect = 2e-16 Identities = 50/125 (40%), Positives = 71/125 (56%), Gaps = 4/125 (3%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQ----AVFWAIEAGYRHIDTAAVYGDE 265 P +L+DG +IP+L G G D+ D + + A A+ AGY H+D A VYG+E Sbjct: 25 PSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGNE 84 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 ++G+ AIA+ + R L+ITTK A V + SL++LGLDYVDLYL+H Sbjct: 85 VELGR----AIAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHS 138 Query: 446 PISSK 460 P +K Sbjct: 139 PFFAK 143 >UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 355 Score = 72.1 bits (169), Expect(2) = 2e-16 Identities = 38/71 (53%), Positives = 49/71 (69%) Frame = +2 Query: 239 DTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLD 418 D A +YG+E +VGQGI A G V R +LF+TTK+W H + + L ESLQRLGLD Sbjct: 80 DAAWIYGNENEVGQGIK---ASG-VPRSELFVTTKIWCTYHRQPEAC--LDESLQRLGLD 133 Query: 419 YVDLYLIHFPI 451 YVDL L+H+P+ Sbjct: 134 YVDLLLVHWPV 144 Score = 35.5 bits (78), Expect(2) = 2e-16 Identities = 21/44 (47%), Positives = 27/44 (61%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHI 238 +LN G +IPV+ LGT + E V +AV AI+AGYRHI Sbjct: 15 KLNTGAEIPVIGLGTWQSAPGE------VAKAVESAIKAGYRHI 52 >UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: Benzil reductase - Bacillus subtilis Length = 276 Score = 87.0 bits (206), Expect = 2e-16 Identities = 50/118 (42%), Positives = 74/118 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L++G ++P LG + + ++ ++V AI+ GYR IDTAA+Y +EE VG GI Sbjct: 10 KLHNGVEMPWFGLGVFK-----VENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI 64 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 E+ G V RE+LFIT+K+WN+ + +SL+RL LDY+DLYLIH+P K Sbjct: 65 KES---G-VAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK 118 >UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep: AkrI - Butyrivibrio fibrisolvens Length = 172 Score = 87.0 bits (206), Expect = 2e-16 Identities = 44/135 (32%), Positives = 77/135 (57%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G IP+ GT + +++ + VR A ++ GYRHIDTAA Y +E+ V I Sbjct: 9 KLNNGTAIPMFGYGTYK-IKDQNEAYNSVRLA----LKNGYRHIDTAAFYENEKFVANAI 63 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + + + RED+F+T+K W + + + +++ + +DY+DLYL+H+P S D Sbjct: 64 KDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFD 123 Query: 467 GSPDNIDYLETWEGM 511 +N + +TW+ M Sbjct: 124 DDWENTN-RQTWKAM 137 >UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=1; Lactobacillus brevis ATCC 367|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 268 Score = 86.6 bits (205), Expect = 3e-16 Identities = 53/131 (40%), Positives = 74/131 (56%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 QL++G IP+L GT D+ D V A+ A++AGYRH+D A +YG+E VG Sbjct: 5 QLSNGVTIPMLGFGTYL-----IDSKD-VPAAIKTALDAGYRHLDCAHIYGNEPAVG--- 55 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 EAI + R DLFIT+K+WN + + ++L L LDY+DLYLIH+P + Sbjct: 56 -EAIKASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWPNEDDFE 114 Query: 467 GSPDNIDYLET 499 + D LET Sbjct: 115 LTLDTWRVLET 125 >UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB49|Rep: ARA1 - unidentified eubacterium SCB49 Length = 280 Score = 86.6 bits (205), Expect = 3e-16 Identities = 47/135 (34%), Positives = 78/135 (57%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+ IP + GT + T ++ ++ A I+AGY+HID AA+Y +E+ VG GI Sbjct: 6 KLNNNINIPAIGFGTWQ-TPDGQTAINAIKTA----IDAGYKHIDAAAIYKNEKGVGLGI 60 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 EA + R+DLF+T+K+WN++ + ++ L LDY+DLYLIH+P ++ Sbjct: 61 KEAN----IDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQF 116 Query: 467 GSPDNIDYLETWEGM 511 + ++ +TW M Sbjct: 117 ENWKQLNN-DTWSAM 130 >UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; Erythrobacter sp. SD-21|Rep: Putative oxidoreductase protein - Erythrobacter sp. SD-21 Length = 272 Score = 85.8 bits (203), Expect = 5e-16 Identities = 51/138 (36%), Positives = 76/138 (55%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P LNDG +IP L GT + E D QAV AI+ GY IDTAA+YG+E+ VG Sbjct: 5 PTLNLNDGRQIPQLGFGTWQ--MEEEDA----PQAVSTAIDVGYWLIDTAAIYGNEKGVG 58 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 +G+ E D+F+ TK+WND + + + L+RLG ++VD+ LIH+P Sbjct: 59 KGVGEW--------SDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWP--- 107 Query: 458 KADGSPDNIDYLETWEGM 511 P+ +++TW+ + Sbjct: 108 ----CPEKDQFVDTWKAL 121 >UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 339 Score = 85.8 bits (203), Expect = 5e-16 Identities = 50/150 (33%), Positives = 82/150 (54%), Gaps = 16/150 (10%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN GY++PV+ GT + ++ ++VR A +EAGYRHID+A + ++E+V GI Sbjct: 9 LNSGYEMPVIGYGTWQ--LPKNLAAERVRDA----LEAGYRHIDSALSFKNQEEVAAGIK 62 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 + V RE+LF+++K+WN H+R + + + E L+ Y+DL +IH+P D Sbjct: 63 DWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDE 122 Query: 470 SP----------------DNIDYLETWEGM 511 P ++DYLETW+ + Sbjct: 123 PPGERGLWPRGANGKMRYSDVDYLETWKAL 152 >UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep: ENSANGP00000029046 - Anopheles gambiae str. PEST Length = 331 Score = 85.8 bits (203), Expect = 5e-16 Identities = 50/120 (41%), Positives = 71/120 (59%), Gaps = 2/120 (1%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G+ IP+ GT + E + Q + +A+EAGYRHIDTA VY +EE +G + Sbjct: 35 KLNTGFDIPLAGFGTYQIHGQEL-----IYQVLDYALEAGYRHIDTAVVYRNEEYIGTAL 89 Query: 287 AEAIAKGLVTREDLFITTKLWNDK-HARGQVVPTLRESLQRLGLDYVDLYLIHFP-ISSK 460 + K + RED+FIT+KL + V +R+SL L DY+DLYLIH+P +S K Sbjct: 90 KTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGK 149 >UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=9; Trichomonas vaginalis G3|Rep: Oxidoreductase, aldo/keto reductase family protein - Trichomonas vaginalis G3 Length = 308 Score = 85.8 bits (203), Expect = 5e-16 Identities = 47/124 (37%), Positives = 72/124 (58%) Frame = +2 Query: 125 KIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAK 304 +IP + LGT + SE D V + EAGY HID A Y +E+ VGQ + + Sbjct: 3 RIPTIGLGTWKSPRSE----DLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDS 58 Query: 305 GLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNI 484 G + RE+++IT+KLWN H V R++L+ L LDY+DLYL+H+P + + G ++ Sbjct: 59 G-IKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSL 117 Query: 485 DYLE 496 + L+ Sbjct: 118 NPLD 121 >UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 323 Score = 85.4 bits (202), Expect = 7e-16 Identities = 47/125 (37%), Positives = 74/125 (59%), Gaps = 3/125 (2%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 QLN+GYK+P+L LGT T++++ + A++ GYR+ DTA Y +E ++GQ Sbjct: 16 QLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQAF 75 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF---PISS 457 +G RED+FITTKL+ K + ++ ++ SL +L Y+DLYLI + P+ + Sbjct: 76 QNIFQQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQWSFTPVLT 134 Query: 458 KADGS 472 DGS Sbjct: 135 NFDGS 139 >UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 287 Score = 85.4 bits (202), Expect = 7e-16 Identities = 50/117 (42%), Positives = 72/117 (61%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +L G ++P+L LGT + E Q++Q+V A++AGYR DTAAVYG+E +G Sbjct: 4 PSVRLMSGTQMPLLGLGTYKLQDHE-----QLKQSVSCALQAGYRAFDTAAVYGNEAHLG 58 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 Q + E + K + RED+FI +KL H LR SL++L +Y+DLYLIH+P Sbjct: 59 QVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWP 114 >UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae str. PEST Length = 310 Score = 85.4 bits (202), Expect = 7e-16 Identities = 47/123 (38%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Frame = +2 Query: 101 CHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQ 280 C L+D + I + +G G + +D + +R A I+ GYR DTA YG+E VG+ Sbjct: 6 CINLSDQHSIALPTIGLGTYSILGADGKEAIRTA----IDVGYRMFDTAVAYGNEAIVGE 61 Query: 281 GIAEAIAK-GLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 I E I + +TR+D FI +KL H + V R +L RLG+DYVDLYL+H P++ Sbjct: 62 AIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVAL 121 Query: 458 KAD 466 +++ Sbjct: 122 QSE 124 >UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 265 Score = 85.4 bits (202), Expect = 7e-16 Identities = 50/107 (46%), Positives = 64/107 (59%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 +P L L G GT S D + R V A+EAGYRH+DTA +Y +E VG+GIA A Sbjct: 1 MPPLELPLGLGT-SRLDDPAECRATVAAALEAGYRHVDTAQMYDNETAVGEGIATAD--- 56 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 V R+D+ + TK+ D A V T R+SL RLGLD VDL +H+P Sbjct: 57 -VDRDDVVVATKIHPDNLAPADVRETARKSLDRLGLDRVDLLYVHWP 102 >UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG2767-PA - Nasonia vitripennis Length = 356 Score = 85.0 bits (201), Expect = 9e-16 Identities = 52/131 (39%), Positives = 77/131 (58%) Frame = +2 Query: 74 YSVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAV 253 + V T+ +L+ G+ +P++ LGT + + + AV A+E+GYRHIDTA Sbjct: 18 FCVITSGYKTIKLSSGHDMPMIGLGTWQMPP------EAIEVAVTAALESGYRHIDTAFT 71 Query: 254 YGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLY 433 YG+EE +G+ + + KG REDLFITTKL V L+ SL++LGL+YV++Y Sbjct: 72 YGNEEAIGKTLKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMY 130 Query: 434 LIHFPISSKAD 466 LIH P + D Sbjct: 131 LIHKPFAFVKD 141 >UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 310 Score = 84.6 bits (200), Expect = 1e-15 Identities = 46/127 (36%), Positives = 78/127 (61%), Gaps = 2/127 (1%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+GY +P++ +GT + E +++ + + G+R IDTA VY +EE +G + Sbjct: 27 RLNNGYDMPLVGIGTYKVRGREV-----IKRVIDESFAVGFRSIDTAVVYRNEEDIGLAL 81 Query: 287 AEAIAKGLVTREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK- 460 E + K + RED+FIT+KL +D ++ ++ +SL+ L Y+DLYLIH+P +S+ Sbjct: 82 KELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASRI 141 Query: 461 ADGSPDN 481 + SPDN Sbjct: 142 LENSPDN 148 >UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep: Oxidoreductase - Lactobacillus plantarum Length = 282 Score = 84.6 bits (200), Expect = 1e-15 Identities = 55/142 (38%), Positives = 75/142 (52%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 T +QL +G IP +A GT + E+ QAV A+ AGYRHIDTA Y +E Sbjct: 2 TVLTTMYQLANGVNIPKVAFGTWQIPGGEA-----TYQAVRAALAAGYRHIDTALAYQNE 56 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 VGQ I ++ G + RE +F+TTKL + + + SL+ LGLDYVDLYL+H Sbjct: 57 ASVGQAIRDS---G-IPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHA 112 Query: 446 PISSKADGSPDNIDYLETWEGM 511 P G + L+ W+ M Sbjct: 113 PWPWGQVGRVYDEANLDVWQAM 134 >UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 281 Score = 84.6 bits (200), Expect = 1e-15 Identities = 56/134 (41%), Positives = 76/134 (56%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G KIP L G + E+ + V A+EAGYRHIDTAA Y +E VG I+ Sbjct: 14 LNNGVKIPQLGFGVFQVPPEETQRI------VEDALEAGYRHIDTAAAYRNEAGVGAAIS 67 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 A G + RED+FITTKL N + +G + S + LG+++VDLYLIH+P+ S+ Sbjct: 68 ---ASG-IPREDIFITTKLRNGE--QGNAHEAFQNSRKALGVEFVDLYLIHWPVPSQG-- 119 Query: 470 SPDNIDYLETWEGM 511 Y E W+ M Sbjct: 120 -----LYTEAWKAM 128 >UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 279 Score = 84.6 bits (200), Expect = 1e-15 Identities = 45/106 (42%), Positives = 65/106 (61%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 +P+L LGT +++ +Q ++V A+EAGYRHIDTA Y +E VG GIA A Sbjct: 17 MPMLGLGTW-----QNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAAAD--- 68 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 V R+D+F+ TK+W + V+ T ESL +LG+D VDL +H+ Sbjct: 69 -VDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHW 113 >UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 274 Score = 84.6 bits (200), Expect = 1e-15 Identities = 50/110 (45%), Positives = 62/110 (56%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G +P L LGT + T R+ V A+ GYRHIDTA YG+E QVG G+ A Sbjct: 8 GTSVPALGLGTWQLTGQSC------RETVETALGMGYRHIDTAQAYGNERQVGLGMDAAA 61 Query: 299 AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 V RED+F+TTKL V + RESL +LG DY+DL LIH+P Sbjct: 62 ----VDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107 >UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate reductase family; n=2; Lactobacillus|Rep: Aldo/keto reductase of diketogulonate reductase family - Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) Length = 273 Score = 84.2 bits (199), Expect = 2e-15 Identities = 52/119 (43%), Positives = 70/119 (58%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+ KIP+ GT + DQ +QAV A E GYR IDTA Y +E+QVG+ + Sbjct: 6 LNNDVKIPIFGFGTYEISP------DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK 59 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 A GL R+++FITTK D + ++ L ESL+R+GLDY DL LIH+P+ D Sbjct: 60 ---ASGL-NRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHDID 112 >UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; Bacteria|Rep: 2,5-didehydrogluconate reductase - Arthrobacter sp. (strain FB24) Length = 291 Score = 84.2 bits (199), Expect = 2e-15 Identities = 51/135 (37%), Positives = 72/135 (53%), Gaps = 13/135 (9%) Frame = +2 Query: 95 APCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQV 274 +P LN+G I L G + +++ L V A+EAGYRH DTAA+YG+E V Sbjct: 4 SPRLSLNNGVLIDQLGFGLYKVPPADAAGL------VTMALEAGYRHFDTAAMYGNETGV 57 Query: 275 GQGIAEAI-------------AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGL 415 G+ I A ++REDLF+TTK+WND H + S+ LG+ Sbjct: 58 GKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGM 117 Query: 416 DYVDLYLIHFPISSK 460 +YVDLYLIH+P + + Sbjct: 118 EYVDLYLIHWPCARR 132 >UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr1 scaffold_22, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 360 Score = 84.2 bits (199), Expect = 2e-15 Identities = 46/113 (40%), Positives = 71/113 (62%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN KIP + LGT + D +AV A+ GYR ID A +YG+E +VG+ +A Sbjct: 14 LNTKAKIPAIGLGTWQSGG------DLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALA 67 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 EA G + RED+F+T+KL+ ++ ++ ++R SL+ LG+ Y+DLYL+H+P Sbjct: 68 EAF-NGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWP 119 >UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 316 Score = 83.8 bits (198), Expect = 2e-15 Identities = 55/132 (41%), Positives = 76/132 (57%), Gaps = 4/132 (3%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G +P L GT R SD ++V +A+ A+EAGYRHIDTA VY +E+ +G+ + E Sbjct: 11 NGTTMPALGFGTWRA----SD--EEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEW 64 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS-SKADGS 472 + G VTR++LFI TKL V L+ SL L L+YVDLY +H P + + DG Sbjct: 65 MDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGP 124 Query: 473 ---PDNIDYLET 499 D + LET Sbjct: 125 FLVEDGLIVLET 136 >UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; Bacteria|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 287 Score = 83.4 bits (197), Expect = 3e-15 Identities = 45/113 (39%), Positives = 63/113 (55%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++G IP + GT + +S L AI GYRH DTA+ YG E +GQ +A Sbjct: 10 LSNGLSIPAVGFGTYKTGDGDSAVLSN-------AIAQGYRHFDTASFYGTETALGQAVA 62 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 E+ + RED F+T+KLW + + +L+RLG DY+DLYLIH+P Sbjct: 63 ESD----IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP 111 >UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 700 Score = 83.0 bits (196), Expect = 4e-15 Identities = 51/127 (40%), Positives = 72/127 (56%) Frame = +2 Query: 74 YSVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAV 253 Y+ S ++ L +G +IP L GT + + +Q AV AI+ GYRHID A Sbjct: 2 YASSVRRSANFTLANGAQIPKLGFGTWKMSK------EQATPAVAHAIKTGYRHIDCAWA 55 Query: 254 YGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLY 433 Y +E+ V GI +A G V R L++T+KLWN H V L SL+ LG DY+DLY Sbjct: 56 YRNEDAVAAGIKKA---G-VPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLY 111 Query: 434 LIHFPIS 454 L+H+P++ Sbjct: 112 LMHWPVA 118 >UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 299 Score = 82.6 bits (195), Expect = 5e-15 Identities = 42/119 (35%), Positives = 71/119 (59%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L++G K+P LG+ R ++++V + A++ GYRHIDTA +Y +E+ +G + Sbjct: 12 LSNGQKMPAFGLGSSR-----VQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALK 66 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 +G RED+F+ TK + K + ++E LQ+L +DYVDL LIH P+++ +D Sbjct: 67 TIFGEGKYKREDIFLVTKQASIKGV--SCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSD 123 >UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase; n=1; Rhodococcus sp. RHA1|Rep: Probable 2,5-didehydrogluconate reductase - Rhodococcus sp. (strain RHA1) Length = 265 Score = 82.6 bits (195), Expect = 5e-15 Identities = 49/108 (45%), Positives = 65/108 (60%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 IP L LGT T ++ +AV IEAGYR IDTA +Y +E+ VG +AE G Sbjct: 4 IPPLGLGTWPLTGPDAT------RAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC---G 54 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 V RE+LF+TTKL H G + + SL+ LGLD +DL+LIH+P+ Sbjct: 55 -VPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPL 101 >UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; Actinomycetales|Rep: 2,5-didehydrogluconate reductase - Kineococcus radiotolerans SRS30216 Length = 289 Score = 82.6 bits (195), Expect = 5e-15 Identities = 55/143 (38%), Positives = 82/143 (57%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVY 256 SVS P LNDG +IP L G + DT QAV A++ GYRHIDTA +Y Sbjct: 6 SVSAMTVPTILLNDGREIPQLGFGVFQ--IEPGDTA----QAVKTALDLGYRHIDTAQMY 59 Query: 257 GDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYL 436 G+E +V QGIA++ G V R+++++T+KL N H + +S+++L +DLYL Sbjct: 60 GNEAEVAQGIADS---G-VPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKL-RGPIDLYL 114 Query: 437 IHFPISSKADGSPDNIDYLETWE 505 IH+P+ + G D++ TW+ Sbjct: 115 IHWPLPTLYGG-----DFVSTWK 132 >UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 419 Score = 82.2 bits (194), Expect = 6e-15 Identities = 54/139 (38%), Positives = 72/139 (51%), Gaps = 1/139 (0%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAI-EAGYRHIDTAAVYGDEEQV 274 P L +G IP+L LGT D AV +A+ E G RHIDTA YG E + Sbjct: 13 PTVPLANGLNIPILGLGTSHVGGYSHD-------AVIYALKECGIRHIDTAKRYGCELLL 65 Query: 275 GQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 G+ I E+ K RE+L+ITTKLW + + ES RLG++Y+DL+LIH+P Sbjct: 66 GKAIQESGVK----REELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWP-D 120 Query: 455 SKADGSPDNIDYLETWEGM 511 ++ G ETW M Sbjct: 121 AQLPGKSSREARAETWRAM 139 >UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase family; n=1; Entamoeba histolytica HM-1:IMSS|Rep: oxidoreductase, aldo/keto reductase family - Entamoeba histolytica HM-1:IMSS Length = 307 Score = 82.2 bits (194), Expect = 6e-15 Identities = 53/131 (40%), Positives = 75/131 (57%), Gaps = 2/131 (1%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G +P + LGT E V +AV A+E GYR ID A Y +E+++G+ Sbjct: 8 LNNGKFMPAIGLGTWLAAPGE------VGKAVTLALENGYRLIDCARFYKNEKEIGEMGI 61 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 E K RE+LF+T+KLW D+ R + + ES+Q L Y+DLYLIH+PI+ K D Sbjct: 62 EPFLKNH-PREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVDA 118 Query: 470 S--PDNIDYLE 496 S P D+L+ Sbjct: 119 SNPPKPEDFLD 129 >UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasidiella neoformans|Rep: Oxidoreductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 321 Score = 82.2 bits (194), Expect = 6e-15 Identities = 55/122 (45%), Positives = 77/122 (63%), Gaps = 3/122 (2%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAA---VYGDEEQVGQ 280 LNDG++IP +A GT + + T QV QA I+ G+ HIDTA VY +EE+VGQ Sbjct: 8 LNDGHRIPAIAFGTWK--IPKEVTPFQVGQA----IDVGFDHIDTAQGRIVYHNEEEVGQ 61 Query: 281 GIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 I E+ GL +R L++TTK W+ +G ++ ESL++LGL+Y+DLYLIH P +K Sbjct: 62 AIKES---GL-SRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQVTK 115 Query: 461 AD 466 D Sbjct: 116 GD 117 >UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to aldo-keto reductase family 1, member B10, partial - Macaca mulatta Length = 275 Score = 81.8 bits (193), Expect = 8e-15 Identities = 47/107 (43%), Positives = 62/107 (57%), Gaps = 6/107 (5%) Frame = +2 Query: 161 TASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITT 340 T L +V++AV AI+AGYRHID A VY +E +VG+ I E I + V REDLFI + Sbjct: 38 TRKPKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVS 97 Query: 341 K------LWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 K LW R V ++L+ L L Y+D+YLIH+P KA Sbjct: 98 KVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKA 144 >UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 138 Score = 81.8 bits (193), Expect = 8e-15 Identities = 43/111 (38%), Positives = 70/111 (63%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L +G +IP++ LGT + T +V QA+ A++ GYRHIDTA +YG+EE +G+ I Sbjct: 9 KLFNGVEIPLIGLGTYKMTDEH-----EVYQAIITALQNGYRHIDTAQIYGNEELIGKAI 63 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 ++ G V R+++F+T+K+WN H + + L+RL DY+DL L+ Sbjct: 64 KDS---G-VPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110 >UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 332 Score = 81.8 bits (193), Expect = 8e-15 Identities = 43/115 (37%), Positives = 72/115 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G +P++ LGT + E T + A++AGYRHIDTA Y +E +G+ + Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKEEMT-----NLLRTALDAGYRHIDTAVNYQNEAMIGESL 63 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 +G +R+DLFI +K++ +K ++ ++++SL+ L LDYVDLY +HFP+ Sbjct: 64 KTIFKEGKYSRKDLFIVSKVFPNKGI--NMLESVKKSLKELQLDYVDLYYLHFPL 116 >UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 288 Score = 81.4 bits (192), Expect = 1e-14 Identities = 51/121 (42%), Positives = 72/121 (59%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 T P LN+ ++P+L LGT R E DT AV A++AGYR DTAAVY +E Sbjct: 2 TDPQPSVLLNNDIQMPLLGLGTFRLQGQE-DTYS----AVDAALKAGYRAFDTAAVYRNE 56 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 +G + + K ++RED+FIT+KL K + ++SL++LGL Y+DLYLIH+ Sbjct: 57 AHLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHW 115 Query: 446 P 448 P Sbjct: 116 P 116 >UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto reductase family - Caulobacter crescentus (Caulobacter vibrioides) Length = 279 Score = 81.4 bits (192), Expect = 1e-14 Identities = 38/79 (48%), Positives = 55/79 (69%) Frame = +2 Query: 212 AIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLR 391 A+E GYRHIDTA +YG+E VG AI V R+++F+TTK+W D+ A G + + Sbjct: 37 ALEIGYRHIDTAQIYGNERDVGA----AIRNSGVKRDEIFLTTKVWIDQFADGDLQRSAE 92 Query: 392 ESLQRLGLDYVDLYLIHFP 448 +SL++LG+D VDL L+H+P Sbjct: 93 KSLEKLGVDQVDLLLLHWP 111 >UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein T08H10.1 - Caenorhabditis elegans Length = 333 Score = 81.4 bits (192), Expect = 1e-14 Identities = 46/117 (39%), Positives = 69/117 (58%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN G ++P+ LGT + E++ +R A ++AGYR IDTA +Y +E +G+ + Sbjct: 8 LNTGAQLPLFGLGTWQ-VKDEAELTVALRAA----LDAGYRLIDTAHLYQNEHIIGKVLH 62 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 E I+ G + RED+F+T+KL HA V + L+ L L+Y+DLYLIH P K Sbjct: 63 EYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFK 119 >UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 339 Score = 81.4 bits (192), Expect = 1e-14 Identities = 50/128 (39%), Positives = 71/128 (55%), Gaps = 1/128 (0%) Frame = +2 Query: 89 AQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 A P LN G K+P + +G +G + V A+ AI+ GYRH+DTA Y +E Sbjct: 3 ANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELV-DALVRAIKVGYRHLDTATGYRNEA 61 Query: 269 QVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 +VGQ A+ + V R ++F+TTKL VV L SL LG+DY+DL+L+H+P Sbjct: 62 EVGQ----AVRQSGVARSEIFVTTKL--RPGGVHDVVQELENSLNELGIDYIDLWLLHWP 115 Query: 449 IS-SKADG 469 +K DG Sbjct: 116 QGFTKDDG 123 >UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto reductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to aldo-keto reductase - Nasonia vitripennis Length = 353 Score = 81.0 bits (191), Expect = 1e-14 Identities = 48/128 (37%), Positives = 74/128 (57%), Gaps = 1/128 (0%) Frame = +2 Query: 74 YSVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAV 253 YS + ++L+ G+ P++ LGT D L+ V A+E G HIDT+ V Sbjct: 21 YSQNVEAGTVYRLSSGHNFPIVGLGTH---GLNEDVLETVLTG---ALEKGIGHIDTSFV 74 Query: 254 YGDEEQVGQGIAEAIAKGLVTREDLFITTKL-WNDKHARGQVVPTLRESLQRLGLDYVDL 430 Y +EE +G+ + + AKG RED+F+T+KL + D H V ++ SL++LGL Y+D+ Sbjct: 75 YKNEETIGKVLKDWFAKG-GKREDIFVTSKLPYYDNHPE-SVEKYIKLSLEKLGLQYLDM 132 Query: 431 YLIHFPIS 454 YLIH P + Sbjct: 133 YLIHAPFA 140 >UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Lin2349 protein - Listeria innocua Length = 294 Score = 81.0 bits (191), Expect = 1e-14 Identities = 47/111 (42%), Positives = 65/111 (58%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 IP + LG + T E + AV AIE GYR DTAAVY +E VGQ I ++ Sbjct: 17 IPYIGLGVFQVTEQEF-----IAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAILDSA--- 68 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 V RE+LFI++K+WN + + +L+ L LDY+DLYLIH+P++ K Sbjct: 69 -VPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK 118 >UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Streptococcus agalactiae|Rep: Oxidoreductase, aldo/keto reductase family - Streptococcus agalactiae H36B Length = 245 Score = 81.0 bits (191), Expect = 1e-14 Identities = 48/114 (42%), Positives = 69/114 (60%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G KIP L G G D L+ Q+V A++ GYR IDTA+ Y +EE VG+ Sbjct: 9 LNNGVKIPSL----GFGVFQIDDPLE-CEQSVLDALQVGYRLIDTASGYLNEEAVGR--- 60 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 AI K + R+++F+ TKLW + + P + +L+RL LDY++LYLIH P+ Sbjct: 61 -AIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPM 113 >UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: 2,5-didehydrogluconate reductase - Clostridium beijerinckii NCIMB 8052 Length = 289 Score = 81.0 bits (191), Expect = 1e-14 Identities = 48/132 (36%), Positives = 68/132 (51%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G KIP + G + E AV AI+ GYRH DTA +YG+E+ +G A Sbjct: 12 NGIKIPQVGFGVYKLNKGED-----FETAVGEAIKIGYRHFDTAKIYGNEKDLGL----A 62 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSP 475 I K + RE+ FIT+K+WN H ++ ++L ++Y+D+YLIHF S Sbjct: 63 IEKSQIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY------ 116 Query: 476 DNIDYLETWEGM 511 YLETW M Sbjct: 117 ----YLETWHAM 124 >UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15; Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B - Bradyrhizobium sp. (strain ORS278) Length = 273 Score = 81.0 bits (191), Expect = 1e-14 Identities = 46/110 (41%), Positives = 64/110 (58%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G ++P L LGT R + R AV A+ GYRHIDTA +Y +E+ +G +A A Sbjct: 8 GVRLPKLGLGTFRMQGTVC------RDAVESALALGYRHIDTAEMYANEDAIGAALAAA- 60 Query: 299 AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + REDL +TTK+W + A + SL++L LD+VDLYLIH+P Sbjct: 61 ---QIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107 >UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 297 Score = 80.6 bits (190), Expect = 2e-14 Identities = 45/130 (34%), Positives = 74/130 (56%), Gaps = 2/130 (1%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN GY IP + GT + T + V A+ A+ AGYR DTA Y +E+++G+ + Sbjct: 14 KLNSGYNIPFVGFGTYKVTG------ENVPPAIDAALTAGYRMFDTAKYYLNEKELGEAL 67 Query: 287 AEAIAKGLVTREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 + K ++R D+F+T+K + K+ R + ESLQ L DY+D+YL+H+P + + Sbjct: 68 KILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDS 127 Query: 464 DGSP-DNIDY 490 D +N +Y Sbjct: 128 DNDDVNNAEY 137 >UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Filobasidiella neoformans|Rep: Aldo-keto reductase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 303 Score = 80.6 bits (190), Expect = 2e-14 Identities = 45/115 (39%), Positives = 70/115 (60%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +++DG IP LG ++ +T D V+ WA+EAGYRH+DTA Y +E G+ I Sbjct: 34 KMHDGNAIPQFGLGVYE--MNDKETYDCVK----WALEAGYRHVDTAEWYENEAPCGKAI 87 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 A+ + +RE++F+T+KL N+ + Q L+ SL+R G++Y DLYL+H I Sbjct: 88 ADFLKATGTSREEIFLTSKLKNNS-SYEQAFVDLKGSLKRSGVEYFDLYLMHSAI 141 >UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 258 Score = 80.6 bits (190), Expect = 2e-14 Identities = 37/84 (44%), Positives = 52/84 (61%) Frame = +2 Query: 197 QAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQV 376 + V A+ GYRH+DTA +YG+E VG G+AE +A V R+++ + TKLW D V Sbjct: 17 EPVATALSLGYRHLDTARIYGNEAVVGDGLAEGLAASDVDRDEVTVATKLWVDDLGAADV 76 Query: 377 VPTLRESLQRLGLDYVDLYLIHFP 448 PT RES LG++ +DL +H P Sbjct: 77 GPTARESADLLGVETLDLLYVHRP 100 >UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 357 Score = 80.2 bits (189), Expect = 3e-14 Identities = 52/120 (43%), Positives = 71/120 (59%), Gaps = 1/120 (0%) Frame = +2 Query: 104 HQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQG 283 + LN G KIP L +GT + S+ +T+ QV ++ G R IDTA VYG E+QVG+G Sbjct: 38 YTLNTGAKIPALGVGTFQDPDSQEETVCQV-------LQRGMRLIDTARVYGVEQQVGRG 90 Query: 284 IAEAIAKGLVTREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 I K V RE++F+ TKLW ND H V + +SL+ L YVDL L+H+P + K Sbjct: 91 IK----KSGVPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPCTFK 145 >UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase related protein - Thermoplasma acidophilum Length = 284 Score = 80.2 bits (189), Expect = 3e-14 Identities = 46/110 (41%), Positives = 65/110 (59%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G K+ V+ +GT S S+ + +R +A++ G IDTA +YG E+ VG+ I Sbjct: 13 GRKVSVIGVGTWSLEGSRSENVRSIR----YALDHGVNFIDTAEMYGTEDIVGEAI---- 64 Query: 299 AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 KG REDLFI TK+W A V+ + ESL++LG DYVDLY +H+P Sbjct: 65 -KGY-RREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112 >UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep: Oxidoreductase - Lactobacillus plantarum Length = 288 Score = 79.8 bits (188), Expect = 3e-14 Identities = 45/119 (37%), Positives = 67/119 (56%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 + P LNDG IP + GT + + T V++A+ GYRHIDTA Y +E++ Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQ-IPDDGSTYQAVKEALV----IGYRHIDTAVAYFNEDE 57 Query: 272 VGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 VGQ I ++ G + R+ +++T+KLW + + SL +L LDY+DLYLIH P Sbjct: 58 VGQAIKDS---G-IPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP 112 >UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; Klebsiella pneumoniae|Rep: Putative uncharacterized protein - Klebsiella pneumoniae Length = 279 Score = 79.8 bits (188), Expect = 3e-14 Identities = 51/132 (38%), Positives = 76/132 (57%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LNDGY +P G G D +RQA ++AG+RH DTA Y +E+ VG+ Sbjct: 8 LNDGYYMP--RPGCGLWLIDNRDVDSLIRQA----LKAGFRHFDTAQAYFNEDGVGR--- 58 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 A+ V RE LFIT+K+ + + + E+L+RLG++Y++L+LIH+PI +K Sbjct: 59 -ALRYTEVPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAK--- 114 Query: 470 SPDNIDYLETWE 505 N+ Y+ETWE Sbjct: 115 ---NL-YVETWE 122 >UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3; Saccharomycetales|Rep: Conjugated polyketone reductase C1 - Candida parapsilosis (Yeast) Length = 304 Score = 79.8 bits (188), Expect = 3e-14 Identities = 54/142 (38%), Positives = 80/142 (56%), Gaps = 10/142 (7%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRG--TASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQ 280 +L++G KIP +A GTG +D Q+ + A+ +G+RHID A +YG +++G Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIGI 68 Query: 281 GIAEAIAKGLVTREDLFITTKL------WNDKHARGQ-VVPTLRESLQRLGLDYVDLYLI 439 + GL R+D+FIT K ++ KH++ Q L+ L+ LGL+YVDLYLI Sbjct: 69 ALKNV---GL-NRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLI 124 Query: 440 HFP-ISSKADGSPDNIDYLETW 502 HFP IS K+ G D +E W Sbjct: 125 HFPYISEKSHG----FDLVEAW 142 >UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Oceanobacillus iheyensis Length = 280 Score = 79.4 bits (187), Expect = 4e-14 Identities = 55/140 (39%), Positives = 73/140 (52%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 Q P L+DG IP + GT R ++ QA+ AI+ GYR IDTA Y +E Sbjct: 4 QIPNVTLHDGLTIPKVGFGTYRLNGNDGV------QAINNAIDHGYRLIDTAYNYENEGT 57 Query: 272 VGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 VG EA+ + RE L IT+KL H + V T++ESL R LDY DLYLIH+P Sbjct: 58 VG----EAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP- 112 Query: 452 SSKADGSPDNIDYLETWEGM 511 +P Y+E W+ + Sbjct: 113 ------NPIQDIYVEAWQAL 126 >UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteobacteria|Rep: Aldo/keto reductase - Shewanella sp. (strain ANA-3) Length = 280 Score = 79.4 bits (187), Expect = 4e-14 Identities = 46/117 (39%), Positives = 68/117 (58%) Frame = +2 Query: 143 LGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTRE 322 LGTG ++ D AV A+E G RHIDTA +YG+E+ VG +AI + RE Sbjct: 20 LGTGTFRLKDNAAFD----AVLMALEEGSRHIDTAQIYGNEQAVG----DAINTSGIPRE 71 Query: 323 DLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNIDYL 493 +LFITTK+W + + + ++ +SL L Y+DL LIH+P++S P ++YL Sbjct: 72 ELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNS---DEPSMVEYL 125 >UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteobacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 274 Score = 79.0 bits (186), Expect = 6e-14 Identities = 43/110 (39%), Positives = 67/110 (60%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G IP L G R + +E V + + A+EAG+RH DTA +Y +E +G+ + A Sbjct: 8 GATIPALGFGVFRMSDAE------VERIIPAALEAGFRHFDTAQIYQNEAALGRALERAG 61 Query: 299 AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 A+ REDLF+TTK+W D ++ + ++ ESL++L +D VDL L+H+P Sbjct: 62 AR----REDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107 >UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep: Aldo-keto reductase - Helicobacter hepaticus Length = 292 Score = 78.6 bits (185), Expect = 8e-14 Identities = 48/113 (42%), Positives = 66/113 (58%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G KIP L LGT R D + V AV A + GYRHIDTA YG+E +G+ Sbjct: 17 LNNGNKIPKLGLGTWR----IDDNV--VEAAVREAFKVGYRHIDTAQAYGNE----RGVG 66 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 EA+ K + RE+LFIT+K+ + ++ SL+ + LD++DL LIH P Sbjct: 67 EAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSP 119 >UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteobacteria|Rep: Aldo/keto reductase - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 273 Score = 78.6 bits (185), Expect = 8e-14 Identities = 37/88 (42%), Positives = 58/88 (65%) Frame = +2 Query: 185 DQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHA 364 D + AV A++ GYRHIDTA Y +E +VG +AI+ ++R +LF+TTK+W D + Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVG----DAISASKISRGELFVTTKVWFDNLS 79 Query: 365 RGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + + +++ SL +L DYVDL L+H+P Sbjct: 80 ADKFITSVQNSLTQLNTDYVDLLLVHWP 107 >UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep: Aldo/keto reductase - Mesorhizobium sp. (strain BNC1) Length = 308 Score = 78.6 bits (185), Expect = 8e-14 Identities = 39/94 (41%), Positives = 58/94 (61%) Frame = +2 Query: 185 DQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHA 364 D+ AV A+ GYRHIDTAA YG+E +VG+GI A G + R+++FI TK+W + Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---G-IARDEVFIETKIWISDYG 97 Query: 365 RGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + + +S +LG+D +DL L+H P+ S D Sbjct: 98 YDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFD 131 >UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 272 Score = 78.2 bits (184), Expect = 1e-13 Identities = 46/113 (40%), Positives = 66/113 (58%) Frame = +2 Query: 116 DGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEA 295 +G +IP + LGT + + V A+ GYRHIDTA VY +E +VG G+ Sbjct: 7 NGARIPAIGLGTWELSGRPC------ARVVEQALRLGYRHIDTAQVYDNEREVGDGVR-- 58 Query: 296 IAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 A G V R+D+F+TTK+W + A + +++ESL RL L VDL L+H+P S Sbjct: 59 -ASG-VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNS 109 >UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; Helicobacter hepaticus|Rep: Putative uncharacterized protein - Helicobacter hepaticus Length = 270 Score = 78.2 bits (184), Expect = 1e-13 Identities = 49/119 (41%), Positives = 70/119 (58%), Gaps = 1/119 (0%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G K+P+L LGT T ++A+ AIE GYR D+A +Y +E ++G I Sbjct: 6 LNNGVKMPILGLGTYSLTGKAG------QKAMSEAIEVGYRLFDSAQMYNNEAELGAAIN 59 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS-SKA 463 A+ KG + RE+ FI TKL + + ++ +SL+ LGLDY+D LIH P S SKA Sbjct: 60 AAV-KGGIKREEFFIQTKLL-ESSSEDLAKKSIEKSLKTLGLDYIDSLLIHMPYSQSKA 116 >UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coagulans 36D1|Rep: Aldo/keto reductase - Bacillus coagulans 36D1 Length = 273 Score = 78.2 bits (184), Expect = 1e-13 Identities = 46/134 (34%), Positives = 74/134 (55%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L +G IP + LGT + E+ AV +A++ GYRHIDTA Y +EE VG+ + Sbjct: 10 LENGVAIPKIGLGTWQVPNGET-----TYHAVSFALKNGYRHIDTAYAYHNEESVGKAVR 64 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 ++ G + R D+F+T+KL + + + + T E++ GL+ +DLYLIH P G Sbjct: 65 DS---G-IDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKG 120 Query: 470 SPDNIDYLETWEGM 511 + + +E W+ M Sbjct: 121 ADYTKENIEVWKAM 134 >UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter sp. (strain FB24) Length = 287 Score = 78.2 bits (184), Expect = 1e-13 Identities = 51/143 (35%), Positives = 81/143 (56%) Frame = +2 Query: 83 STAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGD 262 + + P +L G+ IP L LGT E +T AV +A+++GYR +DTA Y + Sbjct: 9 TASDIPRLKLPHGHTIPRLGLGTWPMLEDECET------AVRFALQSGYRLVDTAFQYRN 62 Query: 263 EEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH 442 EE VG+GI A G V R +LFI++K + H+ V ESL++LGLD++D+++ H Sbjct: 63 EEAVGRGIRTA---G-VPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCH 118 Query: 443 FPISSKADGSPDNIDYLETWEGM 511 +P+ P Y++ W+G+ Sbjct: 119 WPV-------PALGKYVDAWKGL 134 >UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium discoideum AX4 Length = 305 Score = 78.2 bits (184), Expect = 1e-13 Identities = 48/137 (35%), Positives = 76/137 (55%), Gaps = 8/137 (5%) Frame = +2 Query: 125 KIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAK 304 K+P+L +GT + L+ + + +E GYR IDTA++Y +EE++G+ + E + K Sbjct: 26 KMPMLGIGTFK--------LNDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTK 77 Query: 305 --GL----VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 GL + REDLFIT+K + + SL++L LDY+D YLIH+P D Sbjct: 78 NDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLD 137 Query: 467 GSP--DNIDYLETWEGM 511 GS ++I +TW + Sbjct: 138 GSDSGNSIQRAQTWRAL 154 >UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti|Rep: Aldo-keto reductase - Aedes aegypti (Yellowfever mosquito) Length = 284 Score = 78.2 bits (184), Expect = 1e-13 Identities = 47/117 (40%), Positives = 74/117 (63%), Gaps = 3/117 (2%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 +AP +LN+G ++PVL LGT + E + ++ ++ A I+AGYRHIDTA Y +E++ Sbjct: 4 KAPMVKLNNGLEMPVLGLGTW--LSKEGEGVEAIKAA----IDAGYRHIDTAYFYQNEKE 57 Query: 272 VGQGIAEAIAKGLVTREDLFITTKL--WNDKHARGQVVPTLRE-SLQRLGLDYVDLY 433 VG+ I I +G+V REDLF+TTK W+ K+ ++P + LQ +DY+D + Sbjct: 58 VGEAIRAKIEEGVVCREDLFVTTKFIDWDTKN----LMPYDADGKLQFSDVDYIDTW 110 >UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 301 Score = 78.2 bits (184), Expect = 1e-13 Identities = 47/114 (41%), Positives = 63/114 (55%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L+ GY +P + LGT E V AV A+ GYRHID AA Y +E +VG G Sbjct: 8 KLSSGYDMPAVGLGTWLSKPHE------VENAVETALRLGYRHIDAAACYLNENEVGNGW 61 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 K V R+ +FIT+KLWN H V + ++L+ L DY+DLYL+ FP Sbjct: 62 K----KSGVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLV-FP 110 >UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4; Bifidobacterium|Rep: Dehydrogenase or reductase protein - Bifidobacterium longum Length = 289 Score = 77.8 bits (183), Expect = 1e-13 Identities = 46/123 (37%), Positives = 66/123 (53%) Frame = +2 Query: 80 VSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYG 259 ++ A P L DG+ IP + LG R + + V A +EAGYRHID AA Y Sbjct: 6 INPANVPDIALKDGHSIPQVGLGVLR--IDDEGVVPVVESA----LEAGYRHIDGAAGYN 59 Query: 260 DEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 +E VG+ +A + RE L++TTKL + + + SL+ L LDYVD+Y+I Sbjct: 60 NEAGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMI 119 Query: 440 HFP 448 H+P Sbjct: 120 HWP 122 >UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; Parabacteroides merdae ATCC 43184|Rep: Putative uncharacterized protein - Parabacteroides merdae ATCC 43184 Length = 301 Score = 77.8 bits (183), Expect = 1e-13 Identities = 48/120 (40%), Positives = 71/120 (59%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 + P +LN+G ++P L +GT D + V AI+ G+R IDTA YG+E++ Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFL-------VKDNAAERVCHAIKVGFRLIDTAQGYGNEKE 80 Query: 272 VGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 VG+GI + G + R +LFITTK+ + G V +L +SL LG DY+DL LIH+P+ Sbjct: 81 VGEGICRS---G-IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWPV 136 >UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B; n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid reductase B - Corynebacterium sp. (strain SHS752001) Length = 277 Score = 77.4 bits (182), Expect = 2e-13 Identities = 48/133 (36%), Positives = 75/133 (56%), Gaps = 5/133 (3%) Frame = +2 Query: 128 IPVLALGTGR-----GTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAE 292 IP ++L GR G + + D+ A+ AI++GYR +DTA Y +E +VG+ Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGR---- 59 Query: 293 AIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGS 472 A+ V R++L + +K+ +H R + V ++R SL RLGLD +DL LIH+P + Sbjct: 60 AVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP-------N 112 Query: 473 PDNIDYLETWEGM 511 P +L+TW GM Sbjct: 113 PSVGRWLDTWRGM 125 >UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycoplasma gallisepticum Length = 289 Score = 77.0 bits (181), Expect = 2e-13 Identities = 46/134 (34%), Positives = 72/134 (53%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L + YK+P + GT + + Q +AV A+E GYRH+D A +Y ++ V QGI Sbjct: 16 LANNYKMPSIGFGTYKLEDGK-----QTVEAVKTALEVGYRHLDCAEIYENQLSVSQGIK 70 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 G V R+++FIT+K+WND + L+ L L+Y+DL LIH+PI Sbjct: 71 ---LSG-VNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKD 126 Query: 470 SPDNIDYLETWEGM 511 + ++ +TW+ M Sbjct: 127 NWQEVN-AQTWKAM 139 >UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter cryohalolentis K5|Rep: Aldo/keto reductase - Psychrobacter cryohalolentis (strain K5) Length = 282 Score = 77.0 bits (181), Expect = 2e-13 Identities = 47/109 (43%), Positives = 65/109 (59%), Gaps = 2/109 (1%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 IPVL LGT + T D +D V Q + GY HIDTA YG+E +VG+GI ++ G Sbjct: 16 IPVLGLGTWQSTGQ--DCIDVVSQG----LRMGYEHIDTAQAYGNEVEVGKGIKQS---G 66 Query: 308 LVTREDLFITTKLWND--KHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 V R+ F+TTK++ D K ++V + SL+ L DYVDL L+H+P Sbjct: 67 -VARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP 114 >UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phytophthora infestans|Rep: Aldo-keto reductase, putative - Phytophthora infestans (Potato late blight fungus) Length = 255 Score = 77.0 bits (181), Expect = 2e-13 Identities = 41/121 (33%), Positives = 69/121 (57%) Frame = +2 Query: 86 TAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDE 265 + P L G +IP++ LG +S+ + A+ +++ GYRHIDTA +YG+E Sbjct: 2 SVNVPTKILPSGARIPMIGLGV-----YQSEPGPETYNAILTSLKLGYRHIDTAEIYGNE 56 Query: 266 EQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHF 445 E VG+ + ++ G + RE++F+TTKL+ + + + S RLG+ Y+ LYL+H Sbjct: 57 EDVGRAVRDS---G-IPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHA 112 Query: 446 P 448 P Sbjct: 113 P 113 >UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus terreus NIH2624|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 292 Score = 77.0 bits (181), Expect = 2e-13 Identities = 55/144 (38%), Positives = 73/144 (50%), Gaps = 6/144 (4%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESD---TLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 P L DG +P+L GTG + T ++ + + A+E G+ HID A YG E Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63 Query: 269 QVGQGIAEAIAKGLVTREDLFITTKL---WNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 +VG I E+ G + RE LFITTK+ W D V L SL+RL LDYVDLYL+ Sbjct: 64 EVGIAIRES---G-IPREQLFITTKVLEGWKD------VPGALDASLERLQLDYVDLYLL 113 Query: 440 HFPISSKADGSPDNIDYLETWEGM 511 H P P+ D W+G+ Sbjct: 114 HNPYV-----IPNLTDIQSAWKGL 132 >UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep: NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 - Schizosaccharomyces pombe (Fission yeast) Length = 284 Score = 76.6 bits (180), Expect = 3e-13 Identities = 49/113 (43%), Positives = 66/113 (58%), Gaps = 2/113 (1%) Frame = +2 Query: 119 GYKIPVLALGTGRGT-ASESDTLDQ-VRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAE 292 G KIPV A G G E +++ + +V A+ AG+ HID A VYG+EE+VG + E Sbjct: 7 GPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKE 66 Query: 293 AIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPI 451 A V R LFIT+K+ H + L ESL++LG DY+DLYL+H PI Sbjct: 67 A----NVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPI 112 >UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 320 Score = 76.2 bits (179), Expect = 4e-13 Identities = 45/130 (34%), Positives = 70/130 (53%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +L G ++P LA GTG + SD QV A +++G+R ID A VY +E +G Sbjct: 4 PTVRLASGLELPRLAFGTGTALYN-SDAAKQVTMA----LDSGFRFIDGAEVYANEASMG 58 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 GI +A + R D+++ TK+ K + ++ LQ+L +D +D YL+H P Sbjct: 59 AGIESFLASSGLKRNDIYVLTKV--GKEGMKDLQSAIKVELQKLKVDQLDSYLLHLPPRG 116 Query: 458 KADGSPDNID 487 + DG P N+D Sbjct: 117 Q-DGLPSNVD 125 >UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; Lactobacillus reuteri|Rep: 2,5-didehydrogluconate reductase - Lactobacillus reuteri F275 Length = 300 Score = 75.8 bits (178), Expect = 5e-13 Identities = 46/126 (36%), Positives = 74/126 (58%), Gaps = 1/126 (0%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +LN+G+ IP L LG + AS ++T V++A+ Y IDTA YG+E VG Sbjct: 11 PKIKLNNGHLIPQLGLGVWK--ASLAETQQMVKEAIM----NDYVLIDTAKQYGNEAAVG 64 Query: 278 QGIAEAIAKGLVTREDLFITTKLWN-DKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 QGI + R+ +F+TTK++N D+ ++ + E L++L +YVDL L+H+P++ Sbjct: 65 QGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVN 124 Query: 455 SKADGS 472 K + S Sbjct: 125 DKYNES 130 >UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto reductase family - Thermotoga maritima Length = 274 Score = 75.4 bits (177), Expect = 7e-13 Identities = 48/116 (41%), Positives = 66/116 (56%), Gaps = 6/116 (5%) Frame = +2 Query: 119 GYKIPVLALGT-GRGTASESDTL--DQVRQAVFWAIEAGYRHIDTAAVYGD---EEQVGQ 280 G +IP L LGT G G D +++ + + AI+ GY HIDTA YG EE +G+ Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69 Query: 281 GIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 I + REDLFI +K+W R ++ +L +L+RL DYVDLYLIH+P Sbjct: 70 AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP 119 >UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20; Bacteria|Rep: 2,5-diketo-D-gluconate reductase - Acinetobacter sp. (strain ADP1) Length = 297 Score = 75.4 bits (177), Expect = 7e-13 Identities = 49/134 (36%), Positives = 76/134 (56%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+DG+ IP ALG G T +D + +A + GYR +D+A Y +E VG + Sbjct: 27 LHDGHSIP--ALGFGTYTLKGQQGVDTMLRA----LGHGYRMLDSAFNYENEGAVGAAVR 80 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 ++ GL+ R+++FIT+KL HA + + T+ ESL R+ DY+DLYLIH+P Sbjct: 81 QS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP------- 129 Query: 470 SPDNIDYLETWEGM 511 +P Y+E W+ + Sbjct: 130 NPQQGLYIEAWQAL 143 >UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family; n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto reductase family - Lactobacillus acidophilus Length = 289 Score = 75.4 bits (177), Expect = 7e-13 Identities = 45/115 (39%), Positives = 61/115 (53%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P +LNDG +IP L G + D+ +AV AI GYR IDTA Y ++ VG Sbjct: 5 PKIKLNDGNEIPQLGFGV-----FQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVG 59 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIH 442 EAI V R+D+F+TTKLW + + E L+ LG DY+D+ L+H Sbjct: 60 ----EAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110 >UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia ATCC 50803 Length = 313 Score = 75.4 bits (177), Expect = 7e-13 Identities = 36/92 (39%), Positives = 58/92 (63%), Gaps = 2/92 (2%) Frame = +2 Query: 185 DQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI--AKGLVTREDLFITTKLWNDK 358 + V+ AV A+ GYRHID A VY +EE +G+ + A + RED++IT+KLWN Sbjct: 17 EAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYN 76 Query: 359 HARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 H V ++++ L +DY+DL+L+H+P++ Sbjct: 77 HRPELVREQCKKTMSDLQVDYLDLFLVHWPLA 108 >UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; Oceanicola granulosus HTCC2516|Rep: 2,5-didehydrogluconate reductase - Oceanicola granulosus HTCC2516 Length = 275 Score = 74.9 bits (176), Expect = 9e-13 Identities = 44/106 (41%), Positives = 60/106 (56%) Frame = +2 Query: 131 PVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGL 310 P + G G GT D + A+ A+E GYRH+DTA Y E +VG EAI + Sbjct: 9 PEIMPGLGFGTYGRQGE-DGI-SAILCALETGYRHLDTAQDYDTEAEVG----EAIRRAG 62 Query: 311 VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + RE LF+TTK+ G +VP++ SL+ +GLD DL LIH+P Sbjct: 63 LPREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWP 108 >UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona intestinalis|Rep: Aldo-keto reductase 1a - Ciona intestinalis (Transparent sea squirt) Length = 584 Score = 74.9 bits (176), Expect = 9e-13 Identities = 50/143 (34%), Positives = 74/143 (51%), Gaps = 7/143 (4%) Frame = +2 Query: 89 AQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 ++ P +LN GY +P + LGT R + + V A++ GYR +DTA +Y E+ Sbjct: 255 SEIPDVKLNSGYMMPPIGLGTAR-------LFSKTYETVKTALKLGYRMLDTAQIYTGED 307 Query: 269 QVG-------QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVD 427 ++ + I AIA V R +LFI TKL + + + + ESL++L DY+D Sbjct: 308 KINNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDYID 367 Query: 428 LYLIHFPISSKADGSPDNIDYLE 496 L LIH S A G PD+ D E Sbjct: 368 LLLIHDFYMSTACG-PDDTDLPE 389 >UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA - Apis mellifera Length = 321 Score = 74.1 bits (174), Expect = 2e-12 Identities = 44/120 (36%), Positives = 64/120 (53%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L +G +P++ GT + E + A+ A+EAGYRHIDTA Y +E+ +G + Sbjct: 8 LPNGELMPIIGFGTWQAQEKE------LEDALNIALEAGYRHIDTATSYENEKVIGDVLK 61 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 + R D+FI TKL + V ++ SLQ L L+Y+DLYLIH PI + G Sbjct: 62 NWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVG 121 >UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family; n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto reductase family - Mycoplasma penetrans Length = 299 Score = 74.1 bits (174), Expect = 2e-12 Identities = 42/117 (35%), Positives = 67/117 (57%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P LNDGY+IP++ LGT T+ + T + A+ A+E G R DTA++YG+E++VG Sbjct: 35 PLLTLNDGYQIPIIGLGT---TSLHNQTC---KNAIKAALEIGIRLFDTASLYGNEKEVG 88 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 E I + + R ++F+ TKL+ + E+L +L DY+D+ L+H P Sbjct: 89 ----ETIRESNINRNEIFVITKLYPGAQF-ANPEKAIEEALNKLNTDYIDMMLLHHP 140 >UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid reductase; n=1; Gluconobacter oxydans|Rep: Putative 2,5-diketo-D-gluconic acid reductase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 279 Score = 74.1 bits (174), Expect = 2e-12 Identities = 47/133 (35%), Positives = 70/133 (52%) Frame = +2 Query: 113 NDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAE 292 +DG+ +P + LG E T + V++AV + GYR +DTA +Y +EE VG Sbjct: 17 HDGHTMPQIGLGVWETPPDE--TAEVVKEAV----KLGYRSVDTARLYKNEEGVG----- 65 Query: 293 AIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGS 472 KGL ++F+TTKLWND+ + ES + L +DLYLIH+P+ Sbjct: 66 ---KGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPM------- 115 Query: 473 PDNIDYLETWEGM 511 P Y+ETW+ + Sbjct: 116 PAQGQYVETWKAL 128 >UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 264 Score = 74.1 bits (174), Expect = 2e-12 Identities = 41/113 (36%), Positives = 64/113 (56%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LNDG K+P+ LG R D +A++ GYR +DTA +Y +E++VG Sbjct: 15 LNDGRKMPLFGLGVFRLETGCEDVC-------LFALKNGYRMLDTADIYQNEKEVGS--- 64 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 A+ K + RED+++TTKL + + +ES+++L + YVDL+LIH P Sbjct: 65 -AVRKSGLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP 116 >UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr1 scaffold_5, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 247 Score = 73.3 bits (172), Expect = 3e-12 Identities = 44/119 (36%), Positives = 69/119 (57%), Gaps = 10/119 (8%) Frame = +2 Query: 119 GYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAI 298 G IP++ + T + S+T+ ++ AIE GYRH D A Y E+ +G+ I +A+ Sbjct: 13 GKAIPLVGMVTTVYPFAPSETMID---SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAV 69 Query: 299 AKGLV-TREDLFITTKLWNDKHARGQVVPTLRESL---------QRLGLDYVDLYLIHF 445 GL+ +R++LFIT+KLW +V+P L+ +L + L LDY+DLYLIH+ Sbjct: 70 KLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDYLDLYLIHW 128 >UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep: Similarities with sp|Q12458 Saccharomyces cerevisiae YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 127 Score = 73.3 bits (172), Expect = 3e-12 Identities = 38/78 (48%), Positives = 52/78 (66%) Frame = +2 Query: 251 VYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDL 430 +YG+E VG+GI ++ G + RE++F+TTKLWN + L ESL+RLGLDYVDL Sbjct: 1 MYGNETAVGKGIRDS---G-IPREEIFVTTKLWNTQQR--DPASALNESLERLGLDYVDL 54 Query: 431 YLIHFPISSKADGSPDNI 484 +LIH+P+ K G NI Sbjct: 55 FLIHWPVPLKPVGGSKNI 72 >UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Lin2848 protein - Listeria innocua Length = 280 Score = 72.9 bits (171), Expect = 4e-12 Identities = 38/115 (33%), Positives = 68/115 (59%) Frame = +2 Query: 104 HQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQG 283 ++LN+G ++P G + T + ++R A+ A++ GYR DTA+ Y +E+++G Sbjct: 9 YRLNNGIEMPRHGFGVYKLTDEQ-----RMRTALETAVDVGYRLFDTASFYHNEKELGDF 63 Query: 284 IAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 A + K R++ F+TTK+WN + + + +S ++L LD VDLYL+H+P Sbjct: 64 FASSGLK----RDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP 114 >UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia sp. (strain CCS1) Length = 276 Score = 72.9 bits (171), Expect = 4e-12 Identities = 46/136 (33%), Positives = 75/136 (55%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P + +DG +IP + G + D + V AIE GYR ID A +Y +E +G Sbjct: 5 PVIKFHDGAQIPQVGFGIWQVPQ------DIAGETVRSAIEIGYRMIDGAYLYMNEAGLG 58 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISS 457 +G+ A GL R+++F+TTK+WN++ + ++ SL+ +G++ +DL LIH+P+ Sbjct: 59 EGLR---ASGL-PRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV-- 112 Query: 458 KADGSPDNIDYLETWE 505 P YLETW+ Sbjct: 113 -----PSQDLYLETWK 123 >UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized protein - Sulfitobacter sp. NAS-14.1 Length = 274 Score = 72.5 bits (170), Expect = 5e-12 Identities = 38/88 (43%), Positives = 53/88 (60%) Frame = +2 Query: 185 DQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHA 364 D V V A+ G+RHIDTA Y +EEQVG+G+ A V R+++F+TTK+ + + Sbjct: 24 DTVADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRAD----VRRDEVFLTTKILPEHFS 79 Query: 365 RGQVVPTLRESLQRLGLDYVDLYLIHFP 448 SL+RLG DYVDL L+H+P Sbjct: 80 PEAFTAAADASLKRLGTDYVDLLLLHWP 107 >UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7; Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 - Arabidopsis thaliana (Mouse-ear cress) Length = 349 Score = 72.5 bits (170), Expect = 5e-12 Identities = 41/81 (50%), Positives = 51/81 (62%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L G+KIP + LGT R S S V A+ +E GYRHIDTA YGD+ +VGQGI Sbjct: 17 RLLSGHKIPAVGLGTWR---SGSQAAHAVVTAI---VEGGYRHIDTAWEYGDQREVGQGI 70 Query: 287 AEAIAKGLVTREDLFITTKLW 349 A+ GL R DLF+T+KLW Sbjct: 71 KRAMHAGL-ERRDLFVTSKLW 90 >UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; Magnoliophyta|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 304 Score = 72.5 bits (170), Expect = 5e-12 Identities = 41/81 (50%), Positives = 53/81 (65%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 QLN G K+P + LGT +SD V QAV AI+ GYRHID A VYG+EE++G + Sbjct: 9 QLNTGAKMPSVGLGTW-----QSDP-GLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVL 62 Query: 287 AEAIAKGLVTREDLFITTKLW 349 + G+V REDL+IT+KLW Sbjct: 63 KKLFDDGVVKREDLWITSKLW 83 >UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 682 Score = 72.5 bits (170), Expect = 5e-12 Identities = 49/111 (44%), Positives = 67/111 (60%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN G IP + LGT R ++ L V +AV A++ GYRHIDTA G E ++GQ + Sbjct: 415 RLNTGALIPAVGLGTRR---AQKPGL--VYRAVRSALKTGYRHIDTAMSSGVEHEIGQAV 469 Query: 287 AEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 ++ G V+R +++TTKL N H R V L SL LG+DYVDLYL+ Sbjct: 470 KDS---G-VSRSQVWVTTKLDNRWHTR--VQEALDMSLSELGMDYVDLYLM 514 >UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase family; n=1; Haloarcula marismortui|Rep: Oxidoreductase aldo/keto reductase family - Haloarcula marismortui (Halobacterium marismortui) Length = 253 Score = 72.1 bits (169), Expect = 7e-12 Identities = 39/79 (49%), Positives = 45/79 (56%) Frame = +2 Query: 212 AIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLR 391 AI+ GYRH+DTA +Y +E VG GIA A R DL + TKLW D V P Sbjct: 22 AIDCGYRHLDTAQIYDNESTVGAGIAAADTD----RADLTVATKLWIDALEATAVRPATE 77 Query: 392 ESLQRLGLDYVDLYLIHFP 448 SL RLGLD VDL +H P Sbjct: 78 ASLDRLGLDAVDLLYVHRP 96 >UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Aldo/keto reductase - Halorubrum lacusprofundi ATCC 49239 Length = 309 Score = 72.1 bits (169), Expect = 7e-12 Identities = 44/117 (37%), Positives = 65/117 (55%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVG 277 P L G +P L LGT + D DQ+ +V A+ +GY HIDTA Y +EE +G Sbjct: 35 PTQTLPSGDTLPALGLGT----YALDD--DQIADSVRAALSSGYTHIDTAEGYHNEEAIG 88 Query: 278 QGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + +AE R+D+F+T+K+ ++ + SL+RL DY+DLYLIH+P Sbjct: 89 EVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139 >UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 326 Score = 71.7 bits (168), Expect = 9e-12 Identities = 46/123 (37%), Positives = 69/123 (56%), Gaps = 4/123 (3%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 ++N GY+IP+L G + AS+ + L V A +AGYRH+D+AA Y +E Sbjct: 47 RMNSGYEIPILGYGVYQTPASQCEDL------VAKAFDAGYRHVDSAAAYRNEGP----C 96 Query: 287 AEAIAKGLVTREDLFITTKL----WNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPIS 454 A AI + + RED+F T+K+ + ++ + QV TL E+ GL Y+DL LIH P Sbjct: 97 AAAIRRSSIPREDIFFTSKIPPRSLSYENTKAQVAKTLMET----GLGYIDLMLIHAPYG 152 Query: 455 SKA 463 +A Sbjct: 153 GRA 155 >UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreductase protein; n=1; Spiroplasma citri|Rep: Putative aldo/keto reductase oxidoreductase protein - Spiroplasma citri Length = 263 Score = 71.3 bits (167), Expect = 1e-11 Identities = 35/84 (41%), Positives = 51/84 (60%) Frame = +2 Query: 197 QAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQV 376 +A+ A++ GY+ IDTA VY +EE VG+ I + + RED+ I TK+W D G Sbjct: 19 EAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGNT 78 Query: 377 VPTLRESLQRLGLDYVDLYLIHFP 448 + ESL+RL + Y+D+ LIH P Sbjct: 79 TNAVLESLKRLNVTYLDIVLIHRP 102 >UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina baltica OS145|Rep: Aldo/keto reductase - Idiomarina baltica OS145 Length = 263 Score = 71.3 bits (167), Expect = 1e-11 Identities = 45/123 (36%), Positives = 66/123 (53%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 IP +GT R E L V AI+ GY HIDTA YG+E VG+ +A+ Sbjct: 2 IPQFGMGTFRLEGQELTDL------VSAAIDMGYEHIDTAQFYGNEADVGKALAQH---- 51 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNID 487 T +D+F+TTK+W +K A V+ +L+ S +L D +DL LIH+P + + +D Sbjct: 52 --TNKDVFVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPSPNDEVPVEETLD 109 Query: 488 YLE 496 L+ Sbjct: 110 ALQ 112 >UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 71.3 bits (167), Expect = 1e-11 Identities = 44/129 (34%), Positives = 73/129 (56%), Gaps = 1/129 (0%) Frame = +2 Query: 128 IPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKG 307 +P++ +GT + + + L QV A F + GYR IDTA VY +E ++G+ + + + Sbjct: 11 MPLIGIGTWQ--VQKEEILRQVIDAGF---KEGYRFIDTAQVYNNEAKIGRILEKLLPAN 65 Query: 308 LVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGSPDNID 487 + RED++IT+KL + ++ ESL L ++Y+DL LIH+P SS +P N Sbjct: 66 GLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPANKK 125 Query: 488 Y-LETWEGM 511 +E+W M Sbjct: 126 LRVESWNVM 134 >UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pezizomycotina|Rep: Aldo-keto reductase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 283 Score = 71.3 bits (167), Expect = 1e-11 Identities = 47/119 (39%), Positives = 64/119 (53%), Gaps = 2/119 (1%) Frame = +2 Query: 113 NDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAE 292 N KIP L G R Q Q+ A+EAGYRHIDTA YG+E++VG E Sbjct: 15 NSDVKIPRLGFGVYRSPTG------QCVQSSLRALEAGYRHIDTAQFYGNEKEVG----E 64 Query: 293 AIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLG--LDYVDLYLIHFPISSKA 463 A+ K + R D+F+TTK+ + + L ES++++G YVDL+LIH S A Sbjct: 65 ALRKCGIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIHSSSSGSA 123 >UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 301 Score = 70.9 bits (166), Expect = 2e-11 Identities = 42/128 (32%), Positives = 73/128 (57%), Gaps = 1/128 (0%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 + +DGY++P + LG R +T + ++ A+++GYR DTA +Y +E +G + Sbjct: 13 KFSDGYEMPKIGLGISR-----IETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSL 67 Query: 287 AEAIAKGLVTREDLFITTKLWN-DKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKA 463 + + + +TRED+FITTK+ +++ + L SL L DYVDL LIH+P + Sbjct: 68 KKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYP-RDRD 126 Query: 464 DGSPDNID 487 G+ D+ + Sbjct: 127 TGNDDDYE 134 >UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family protein; n=4; Oligohymenophorea|Rep: Oxidoreductase, aldo/keto reductase family protein - Tetrahymena thermophila SB210 Length = 297 Score = 70.5 bits (165), Expect = 2e-11 Identities = 47/142 (33%), Positives = 74/142 (52%), Gaps = 2/142 (1%) Frame = +2 Query: 92 QAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQ 271 + P +G IP + GT ++D + V +A ++ GY HIDTA+VY +E+ Sbjct: 12 KVPILNFREGGSIPQIGYGTYE--LRQNDCIIGVTEA----LKIGYTHIDTASVYRNEQD 65 Query: 272 VGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP- 448 + + I A G + REDLFIT+K+ + Q +++ L RL + Y+D LIH+P Sbjct: 66 IAKVIHNP-AYG-IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPG 123 Query: 449 ISSKADGSPDNIDY-LETWEGM 511 +S P N LETW+ + Sbjct: 124 VSKLPPNDPKNAQIRLETWKAL 145 >UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetrans|Rep: Oxidoreductase - Mycoplasma penetrans Length = 289 Score = 70.1 bits (164), Expect = 3e-11 Identities = 47/126 (37%), Positives = 70/126 (55%) Frame = +2 Query: 80 VSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYG 259 + T+ LN+G KIP ++G G + +T D V++A I GYR IDTA Y Sbjct: 1 MKTSNVKLITLNNGNKIP--SIGFGVFQIPKEETADCVKKA----ISIGYRLIDTAQAYH 54 Query: 260 DEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLI 439 +E++ G GI G V RE++F+TTK+W + R ++ ESL+RL Y+DL L+ Sbjct: 55 NEKETGLGIK---LSG-VKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLILL 108 Query: 440 HFPISS 457 H P + Sbjct: 109 HQPFGN 114 >UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Actinobacillus succinogenes 130Z|Rep: Aldo/keto reductase precursor - Actinobacillus succinogenes 130Z Length = 315 Score = 69.7 bits (163), Expect = 4e-11 Identities = 40/115 (34%), Positives = 72/115 (62%), Gaps = 1/115 (0%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +LN+G ++P++ +G T +Q ++V A++AGYR IDTA +Y +E+ VG+ + Sbjct: 46 KLNNGIEMPIIGIGVWTLTP------EQTEKSVGEALKAGYRLIDTARMYRNEQAVGRAV 99 Query: 287 AEAIAKGLVTREDLFITTKLW-NDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 ++ G + RE++FITTK++ + +A + + E L+ L DY+DL L+H+P Sbjct: 100 RDS---G-IPREEIFITTKIYGSGDYANAEA--AINERLRLLDTDYIDLLLLHYP 148 >UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia ATCC 50803 Length = 303 Score = 69.7 bits (163), Expect = 4e-11 Identities = 34/90 (37%), Positives = 56/90 (62%), Gaps = 2/90 (2%) Frame = +2 Query: 197 QAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGL--VTREDLFITTKLWNDKHARG 370 +A+ A++ GYRH D A YG+E +G+ E V REDL+I +KLW + H Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78 Query: 371 QVVPTLRESLQRLGLDYVDLYLIHFPISSK 460 +V + E+L+ L L+Y+D++L+H+P++ K Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIK 108 >UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Saccharomycetales|Rep: Potential aldo/keto reductase - Candida albicans (Yeast) Length = 319 Score = 69.7 bits (163), Expect = 4e-11 Identities = 47/135 (34%), Positives = 75/135 (55%), Gaps = 6/135 (4%) Frame = +2 Query: 77 SVSTAQAPCHQLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVY 256 S+ + ++LN+G IPV+ GT AS++ L + A++ GYRHIDTA Y Sbjct: 7 SIQLTRQSTYKLNNGSHIPVIGFGTYLLDASQAADL------TYQALKDGYRHIDTALAY 60 Query: 257 GDEEQVGQGIAEAIA-KGLVTREDLFITTKLWNDKHARG-----QVVPTLRESLQRLGLD 418 +E++V QGI + V R D++ TTK+ D + G + V ++ ++ ++ Sbjct: 61 HNEKEVSQGIKRFLKDHPEVQRSDIWFTTKI--DTQSLGYEETKKAVERIKNDVKD-NIE 117 Query: 419 YVDLYLIHFPISSKA 463 YVDL LIH P++SKA Sbjct: 118 YVDLILIHSPLASKA 132 >UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Aldo/keto reductase - Victivallis vadensis ATCC BAA-548 Length = 287 Score = 69.3 bits (162), Expect = 5e-11 Identities = 48/122 (39%), Positives = 61/122 (50%), Gaps = 4/122 (3%) Frame = +2 Query: 89 AQAPCHQLNDGYKIPVLALGTGR-GTASESDTL--DQVRQAVFWAIEAGYRHIDTAAVY- 256 + P L +G+ IPVL GT R G DT D A+ I G HIDTA +Y Sbjct: 2 SDVPWKSLKNGFAIPVLGQGTWRMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMYA 61 Query: 257 GDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYL 436 G + GIA +G + R D F+T K+W V+ SL+RLG DY+DLYL Sbjct: 62 GGHAEELVGIAMK-GQG-IRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDLYL 119 Query: 437 IH 442 IH Sbjct: 120 IH 121 >UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula marismortui (Halobacterium marismortui) Length = 667 Score = 69.3 bits (162), Expect = 5e-11 Identities = 37/111 (33%), Positives = 61/111 (54%) Frame = +2 Query: 140 ALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTR 319 A+G G + +D+ ++ A++AGYR +D+A +YG+E ++G+ +A A G R Sbjct: 380 AIGFGCSRYRDGTYIDRA-DSIAAALDAGYRLLDSAELYGNEHRIGRILA---APGAPDR 435 Query: 320 EDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADGS 472 +FI K+W H R ++ R SL LG+D D Y +H+P + GS Sbjct: 436 RRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGS 486 >UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 282 Score = 68.9 bits (161), Expect = 6e-11 Identities = 46/120 (38%), Positives = 65/120 (54%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 LN+G IP + LGT E D + AV +A++ Y IDTA VY +E VG+G+ Sbjct: 6 LNNGITIPQVGLGT---YLLEPD---DAQSAVTYALDNDYTLIDTANVYVNERAVGRGM- 58 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFPISSKADG 469 A +K R+++F+ TKLW R V E+L+RLG DY+DL ++H P G Sbjct: 59 RASSK---ARDEIFLETKLWPSFFERASAV---EETLERLGTDYIDLMILHQPAGDTVAG 112 >UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. precursor; n=1; Aspergillus niger|Rep: Contig An01c0460, complete genome. precursor - Aspergillus niger Length = 351 Score = 68.9 bits (161), Expect = 6e-11 Identities = 41/97 (42%), Positives = 55/97 (56%) Frame = +2 Query: 131 PVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGL 310 P + LGT +G A V++AV A+ GYRHIDTA YG+E +VG EAI + Sbjct: 47 PAVGLGTFQGDAGNRG----VKEAVLQALRCGYRHIDTATAYGNEIEVG----EAIKESR 98 Query: 311 VTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDY 421 + RE++ +TTKL H V L SL+RL L+Y Sbjct: 99 IPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNY 135 >UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 - Apis mellifera Length = 292 Score = 68.5 bits (160), Expect = 8e-11 Identities = 43/134 (32%), Positives = 71/134 (52%), Gaps = 3/134 (2%) Frame = +2 Query: 110 LNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGIA 289 L+ GY +P++ GT + E V Q V ++ G+R IDTA Y +EE +G + Sbjct: 10 LSSGYDMPLIGFGTYKIQGREL-----VYQVVDESLNVGFRSIDTAVGYRNEEDIGYALK 64 Query: 290 EAIAKGLVTREDLFITTKLWNDKHARGQ-VVPTLRESLQRLGLDYVDLYLIHFPISSKAD 466 + K + R D+FITTKL + + + +++SL+ Y+DLYLIH+P +++ Sbjct: 65 NLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIP 124 Query: 467 GSPDNIDYL--ETW 502 + N L +TW Sbjct: 125 ETSTNNPSLRAKTW 138 >UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; Caenorhabditis elegans|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 287 Score = 68.5 bits (160), Expect = 8e-11 Identities = 39/116 (33%), Positives = 66/116 (56%), Gaps = 2/116 (1%) Frame = +2 Query: 107 QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQVGQGI 286 +L +G +IP LALGT DQ+ AV A++ GYR DTA Y +E+ +G + Sbjct: 3 KLKNGQEIPKLALGTYEAKG------DQLFAAVDEALKVGYRSFDTAKYYENEKDLGLAL 56 Query: 287 AEAIAKGLVTREDLFITTKL--WNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 + + + ED+++T+K+ ++ K+A + + ESL+ L Y+DL L+H+P Sbjct: 57 KTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYP 112 >UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Schizosaccharomyces pombe|Rep: Xylose and arabinose reductase - Schizosaccharomyces pombe (Fission yeast) Length = 283 Score = 68.5 bits (160), Expect = 8e-11 Identities = 37/83 (44%), Positives = 50/83 (60%) Frame = +2 Query: 212 AIEAGYRHIDTAAVYGDEEQVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLR 391 A+++GYRHIDTAAVYG+E+ G+ I + K V R D+F+T+KL N +R Sbjct: 41 ALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANCSDYY-STRAAIR 99 Query: 392 ESLQRLGLDYVDLYLIHFPISSK 460 SL LG Y+DL+LI P K Sbjct: 100 SSLHHLG-TYIDLFLIQSPAGGK 121 >UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep: ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 310 Score = 68.5 bits (160), Expect = 8e-11 Identities = 47/125 (37%), Positives = 69/125 (55%), Gaps = 5/125 (4%) Frame = +2 Query: 101 CH--QLNDGYKIPVLALGTGRGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEEQV 274 CH +L+DG +IP + LG + SE V+ V+ A+E GYR D+A Y +E+ V Sbjct: 10 CHFRRLSDGTQIPSVGLGVYQ--VSEQT----VQDLVYEALEVGYRLFDSAQAYHNEDGV 63 Query: 275 GQGIAEAI--AKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLG-LDYVDLYLIHF 445 +GIA + A G RED++ TTK+ H +L +SL G L Y+DL L+H Sbjct: 64 ARGIAAWLKHAPGR-RREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHA 122 Query: 446 PISSK 460 P+S + Sbjct: 123 PMSDR 127 >UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 302 Score = 68.5 bits (160), Expect = 8e-11 Identities = 44/120 (36%), Positives = 67/120 (55%), Gaps = 3/120 (2%) Frame = +2 Query: 98 PCHQLNDGYKIPVLALGTG---RGTASESDTLDQVRQAVFWAIEAGYRHIDTAAVYGDEE 268 P +L++G +IP + G+G + E + + + AV AI AG+ HIDTA YG E+ Sbjct: 4 PKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELI-DAVVSAINAGHLHIDTAEFYGTEK 62 Query: 269 QVGQGIAEAIAKGLVTREDLFITTKLWNDKHARGQVVPTLRESLQRLGLDYVDLYLIHFP 448 Q+G EAI + V R+D+F+T+K A + ++ L+ L DY DL+LIH P Sbjct: 63 QIG----EAIKESGVPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLIHVP 117 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 526,783,467 Number of Sequences: 1657284 Number of extensions: 10291943 Number of successful extensions: 29220 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 27944 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 28702 length of database: 575,637,011 effective HSP length: 95 effective length of database: 418,195,031 effective search space used: 30946432294 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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