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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= S06A01NCLL0002_E12
         (490 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U96114-1|AAC51325.1|  870|Homo sapiens WWP2 protein.                  245   7e-65
BC064531-1|AAH64531.1|  870|Homo sapiens WWP2 protein protein.        245   7e-65
BC013645-1|AAH13645.1|  870|Homo sapiens WW domain containing E3...   245   7e-65
AK126332-1|BAC86528.1|  343|Homo sapiens protein ( Homo sapiens ...   245   7e-65
U96113-1|AAC51324.1|  684|Homo sapiens WWP1 protein.                  239   4e-63
BC036065-1|AAH36065.1|  922|Homo sapiens WW domain containing E3...   239   4e-63
AY345857-1|AAQ22764.1|  922|Homo sapiens TGIF-interacting ubiqui...   239   4e-63
AY043361-1|AAK94668.1|  922|Homo sapiens WW domain-containing pr...   239   4e-63
BC011571-1|AAH11571.1|  903|Homo sapiens ITCH protein protein.        239   5e-63
AL356299-4|CAI17959.1|  903|Homo sapiens itchy homolog E3 ubiqui...   239   5e-63
AL356299-3|CAI17960.1|  862|Homo sapiens itchy homolog E3 ubiqui...   239   5e-63
AL109923-6|CAI21458.1|  903|Homo sapiens itchy homolog E3 ubiqui...   239   5e-63
AL109923-5|CAI21459.1|  862|Homo sapiens itchy homolog E3 ubiqui...   239   5e-63
AF095745-1|AAK39399.1|  862|Homo sapiens ubiquitin protein ligas...   239   5e-63
AF038564-1|AAC04845.1|  739|Homo sapiens atrophin-1 interacting ...   239   5e-63
AB209747-1|BAD92984.1|  605|Homo sapiens itchy homolog E3 ubiqui...   239   5e-63
AB056663-1|BAB39389.1|  862|Homo sapiens ubiquitin protein ligas...   239   5e-63
BC015380-1|AAH15380.2|  300|Homo sapiens WWP1 protein protein.        215   7e-56
BC111945-1|AAI11946.1|  748|Homo sapiens SMAD specific E3 ubiqui...   165   7e-41
BC093876-1|AAH93876.1|  748|Homo sapiens SMAD specific E3 ubiqui...   165   7e-41
AY014180-1|AAG50421.1|  748|Homo sapiens E3 ubiquitin ligase Smu...   165   7e-41
AF310676-1|AAG45422.1|  748|Homo sapiens E3 ubiquitin ligase SMU...   165   7e-41
AF301463-1|AAG25641.1|  748|Homo sapiens ubiquitin E3 ligase SMU...   165   7e-41
AF464850-1|AAM90910.1|  757|Homo sapiens Smad-ubiquitin E3 ligas...   164   1e-40
AF199364-1|AAF08298.2|  722|Homo sapiens E3 ubiquitin ligase SMU...   164   1e-40
AC004893-2|AAC62434.1|  712|Homo sapiens WUGSC:H_DJ0808A01.2 pro...   164   1e-40
AB046845-1|BAB13451.1|  859|Homo sapiens KIAA1625 protein protein.    164   1e-40
D42055-1|BAA07655.1|  927|Homo sapiens KIAA0093 protein.              155   1e-37
AY550969-1|AAT52215.1|  900|Homo sapiens cell proliferation-indu...   155   1e-37
DQ181796-1|ABA10330.1|  834|Homo sapiens NEDD4L variant protein.      150   3e-36
BC032597-1|AAH32597.1|  911|Homo sapiens NEDD4L protein protein.      150   3e-36
BC019345-1|AAH19345.1|  855|Homo sapiens Unknown (protein for IM...   150   3e-36
BC000621-1|AAH00621.2|  855|Homo sapiens NEDD4L protein protein.      150   3e-36
AY312514-1|AAP75706.1|  975|Homo sapiens NEDD4.2 protein.             150   3e-36
AY112985-1|AAM76730.1|  947|Homo sapiens ubiquitin ligase NEDD4h...   150   3e-36
AY112984-1|AAM76729.1|  967|Homo sapiens ubiquitin ligase NEDD4g...   150   3e-36
AY112983-1|AAM76728.1|  854|Homo sapiens ubiquitin ligase NEDD4f...   150   3e-36
AL137469-1|CAB70754.1|  820|Homo sapiens hypothetical protein pr...   150   3e-36
AF385931-1|AAM46208.1|  854|Homo sapiens ubiquitin ligase NEDD4L...   150   3e-36
AF210730-1|AAG43524.1|  854|Homo sapiens NEDD4La protein.             150   3e-36
AB071179-1|BAB69424.1|  955|Homo sapiens NEDD4-like ubiquitin li...   150   3e-36
AB007899-1|BAA23711.1|  995|Homo sapiens KIAA0439 protein.            150   3e-36
BC151227-1|AAI51228.1| 1606|Homo sapiens HECT, C2 and WW domain ...   132   8e-31
AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin li...   132   8e-31
AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein.            132   8e-31
BC009527-1|AAH09527.1|  288|Homo sapiens SMURF2 protein protein.      128   1e-29
BC034982-1|AAH34982.1|  909|Homo sapiens HECT domain and ankyrin...   126   3e-29
AL590402-2|CAH74024.1|  903|Homo sapiens HECT domain and ankyrin...   126   3e-29
AL590402-1|CAH74023.1|  562|Homo sapiens HECT domain and ankyrin...   126   3e-29
AL513472-2|CAH71890.1|  903|Homo sapiens HECT domain and ankyrin...   126   3e-29
AL513472-1|CAH71889.1|  562|Homo sapiens HECT domain and ankyrin...   126   3e-29
AL357315-1|CAI16815.1|  903|Homo sapiens HECT domain and ankyrin...   126   3e-29
AB037741-1|BAA92558.1|  567|Homo sapiens KIAA1320 protein protein.    126   3e-29
BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain ...   126   5e-29
BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain ...   126   5e-29
AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein.    126   5e-29
Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory elem...   122   9e-28
Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory elem...   122   9e-28
Z97054-1|CAI42644.1| 1196|Homo sapiens upstream regulatory eleme...   122   9e-28
Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory eleme...   122   9e-28
DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase ...   122   9e-28
BC107576-1|AAI07577.1|  332|Homo sapiens HUWE1 protein protein.       122   9e-28
BC063505-1|AAH63505.1|  388|Homo sapiens HUWE1 protein protein.       122   9e-28
BC002602-1|AAH02602.2|  442|Homo sapiens HUWE1 protein protein.       122   9e-28
AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.               122   9e-28
AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1 p...   122   9e-28
AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory ele...   122   9e-28
AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory ele...   122   9e-28
AL592046-1|CAI39578.1| 1196|Homo sapiens upstream regulatory ele...   122   9e-28
AK223167-1|BAD96887.1|  439|Homo sapiens E3 ubiquitin protein li...   122   9e-28
AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LAS...   122   9e-28
AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.            122   9e-28
CR456813-1|CAG33094.1|  308|Homo sapiens UREB1 protein.               112   7e-25
AF057569-1|AAC62492.1|  308|Homo sapiens upstream regulatory ele...   112   7e-25
BX537403-1|CAD97645.1| 1068|Homo sapiens hypothetical protein pr...    66   6e-11
BC141880-1|AAI41881.1| 1068|Homo sapiens ubiquitin protein ligas...    66   6e-11
BC032301-1|AAH32301.1| 1026|Homo sapiens UBE3B protein protein.        66   6e-11
AF251046-1|AAK28419.2| 1068|Homo sapiens UBE3B variant 1 protein.      66   6e-11
X98033-1|CAA66656.1|  852|Homo sapiens E6-AP protein.                  58   2e-08
X98032-1|CAA66655.1|  852|Homo sapiens E6-AP protein.                  58   2e-08
X98031-1|CAA66654.1|  852|Homo sapiens E6-AP protein.                  58   2e-08
X98021-1|CAA66653.1|  852|Homo sapiens E6-AP protein.                  58   2e-08
U84404-1|AAB49301.1|  852|Homo sapiens E6-associated protein E6-...    58   2e-08
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.               58   2e-08
BC009271-1|AAH09271.1|  585|Homo sapiens UBE3A protein protein.        58   2e-08
BC002582-1|AAH02582.2|  872|Homo sapiens ubiquitin protein ligas...    58   2e-08
AF273050-1|AAG34910.1|  852|Homo sapiens CTCL tumor antigen se37...    58   2e-08
AF016708-1|AAB69154.1|  852|Homo sapiens E6-AP ubiquitin-protein...    58   2e-08
AB194232-2|BAD69554.1|  852|Homo sapiens ubiquitin ligase E3A is...    58   2e-08
L07557-1|AAA35542.1|  874|Homo sapiens oncogenic protein-associa...    53   6e-07
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p...    51   2e-06
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin...    51   2e-06
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p...    51   2e-06
AL356741-1|CAH74146.1|  907|Homo sapiens hect domain and RLD 4 p...    51   2e-06
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p...    51   2e-06
AL133551-1|CAI16031.1|  907|Homo sapiens hect domain and RLD 4 p...    51   2e-06
AB046813-1|BAB13419.1|  953|Homo sapiens KIAA1593 protein protein.     51   2e-06
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p...    47   3e-05
BC035775-1|AAH35775.2|  396|Homo sapiens HERC6 protein protein.        47   3e-05
AY653201-1|AAV66895.1|  986|Homo sapiens HERC6 splice variant pr...    47   3e-05
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.                47   3e-05
AC004975-1|AAD51453.1|  415|Homo sapiens unknown protein.              47   3e-05
AK000644-1|BAA91303.1|  379|Homo sapiens protein ( Homo sapiens ...    46   5e-05
BC032944-1|AAH32944.1|  789|Homo sapiens KIAA0317 protein protein.     46   7e-05
AC007956-1|AAF61276.1|  823|Homo sapiens KIAA0317 protein.             46   7e-05
AB002315-1|BAA20775.2|  826|Homo sapiens KIAA0317 protein.             46   7e-05
AL834183-1|CAD38880.1|  523|Homo sapiens hypothetical protein pr...    46   9e-05
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.                46   9e-05
D13635-1|BAA02799.2| 1086|Homo sapiens KIAA0010 protein.               45   2e-04
AL161798-4|CAH70053.1|  776|Homo sapiens HECT domain containing ...    44   4e-04
AL161798-1|CAH70050.1|  426|Homo sapiens HECT domain containing ...    44   4e-04
BC040187-1|AAH40187.1|  776|Homo sapiens HECT domain containing ...    43   7e-04
D28476-1|BAA05837.2| 2005|Homo sapiens KIAA0045 protein.               38   0.014
BC114556-1|AAI14557.1| 2040|Homo sapiens TRIP12 protein protein.       38   0.014
BC113891-1|AAI13892.1| 1722|Homo sapiens TRIP12 protein protein.       38   0.014
AC093384-2|AAY14681.1| 1299|Homo sapiens unknown protein.              38   0.014
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas...    37   0.033
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei...    37   0.033
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.                   37   0.043
BC040929-1|AAH40929.1|  651|Homo sapiens HERC1 protein protein.        37   0.043
BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation ...    31   1.6  
BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation ...    31   1.6  
AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alp...    31   1.6  
AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation ...    31   1.6  
AC104134-2|AAY24331.1|  970|Homo sapiens unknown protein.              31   1.6  
AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation ...    29   6.5  

>U96114-1|AAC51325.1|  870|Homo sapiens WWP2 protein.
          Length = 870

 Score =  245 bits (599), Expect = 7e-65
 Identities = 105/139 (75%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF+FIGRFIAMALYH
Sbjct: 559 IAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYH 618

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GFT+PFYKRMLNK+ T+KD+ESIDPEFYNS+VWIK+NN++ECGLE++F  D E+
Sbjct: 619 GKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEI 678

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG+V  HELK  G+  RVT
Sbjct: 679 LGKVTTHELKEGGESIRVT 697



 Score = 35.9 bits (79), Expect = 0.075
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+ ++T WR TRG+E
Sbjct: 698 EENKEEYIMLLTDWRFTRGVE 718


>BC064531-1|AAH64531.1|  870|Homo sapiens WWP2 protein protein.
          Length = 870

 Score =  245 bits (599), Expect = 7e-65
 Identities = 105/139 (75%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF+FIGRFIAMALYH
Sbjct: 559 IAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYH 618

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GFT+PFYKRMLNK+ T+KD+ESIDPEFYNS+VWIK+NN++ECGLE++F  D E+
Sbjct: 619 GKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEI 678

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG+V  HELK  G+  RVT
Sbjct: 679 LGKVTTHELKEGGESIRVT 697



 Score = 35.9 bits (79), Expect = 0.075
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+ ++T WR TRG+E
Sbjct: 698 EENKEEYIMLLTDWRFTRGVE 718


>BC013645-1|AAH13645.1|  870|Homo sapiens WW domain containing E3
           ubiquitin protein ligase 2 protein.
          Length = 870

 Score =  245 bits (599), Expect = 7e-65
 Identities = 105/139 (75%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF+FIGRFIAMALYH
Sbjct: 559 IAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYH 618

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GFT+PFYKRMLNK+ T+KD+ESIDPEFYNS+VWIK+NN++ECGLE++F  D E+
Sbjct: 619 GKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEI 678

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG+V  HELK  G+  RVT
Sbjct: 679 LGKVTTHELKEGGESIRVT 697



 Score = 35.9 bits (79), Expect = 0.075
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+ ++T WR TRG+E
Sbjct: 698 EENKEEYIMLLTDWRFTRGVE 718


>AK126332-1|BAC86528.1|  343|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44359 fis, clone TRACH3007479, highly  similar
           to Homo sapiens Nedd-4-like ubiquitin-protein ligase
           (WWP2). ).
          Length = 343

 Score =  245 bits (599), Expect = 7e-65
 Identities = 105/139 (75%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF+FIGRFIAMALYH
Sbjct: 120 IAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYH 179

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GFT+PFYKRMLNK+ T+KD+ESIDPEFYNS+VWIK+NN++ECGLE++F  D E+
Sbjct: 180 GKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDMEI 239

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG+V  HELK  G+  RVT
Sbjct: 240 LGKVTTHELKEGGESIRVT 258



 Score = 35.9 bits (79), Expect = 0.075
 Identities = 12/21 (57%), Positives = 17/21 (80%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+ ++T WR TRG+E
Sbjct: 259 EENKEEYIMLLTDWRFTRGVE 279


>U96113-1|AAC51324.1|  684|Homo sapiens WWP1 protein.
          Length = 684

 Score =  239 bits (585), Expect = 4e-63
 Identities = 105/139 (75%), Positives = 123/139 (88%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF FIGRFIAMAL+H
Sbjct: 422 LAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFH 481

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKRML+KKLT+KD+ESID EFYNSL+WI+DNNI+ECGLEM+FSVD E+
Sbjct: 482 GKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEI 541

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG+V  H+LK  G    VT
Sbjct: 542 LGKVTSHDLKLGGSNILVT 560



 Score = 31.9 bits (69), Expect = 1.2
 Identities = 9/21 (42%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+ ++T+WR +RG++
Sbjct: 561 EENKDEYIGLMTEWRFSRGVQ 581


>BC036065-1|AAH36065.1|  922|Homo sapiens WW domain containing E3
            ubiquitin protein ligase 1 protein.
          Length = 922

 Score =  239 bits (585), Expect = 4e-63
 Identities = 105/139 (75%), Positives = 123/139 (88%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF FIGRFIAMAL+H
Sbjct: 611  LAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFH 670

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            G+FI +GF++PFYKRML+KKLT+KD+ESID EFYNSL+WI+DNNI+ECGLEM+FSVD E+
Sbjct: 671  GKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEI 730

Query: 369  LGQVIHHELKPAGDKERVT 425
            LG+V  H+LK  G    VT
Sbjct: 731  LGKVTSHDLKLGGSNILVT 749



 Score = 31.9 bits (69), Expect = 1.2
 Identities = 9/21 (42%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+ ++T+WR +RG++
Sbjct: 750 EENKDEYIGLMTEWRFSRGVQ 770


>AY345857-1|AAQ22764.1|  922|Homo sapiens TGIF-interacting ubiquitin
            ligase 1 protein.
          Length = 922

 Score =  239 bits (585), Expect = 4e-63
 Identities = 105/139 (75%), Positives = 123/139 (88%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF FIGRFIAMAL+H
Sbjct: 611  LAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFH 670

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            G+FI +GF++PFYKRML+KKLT+KD+ESID EFYNSL+WI+DNNI+ECGLEM+FSVD E+
Sbjct: 671  GKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEI 730

Query: 369  LGQVIHHELKPAGDKERVT 425
            LG+V  H+LK  G    VT
Sbjct: 731  LGKVTSHDLKLGGSNILVT 749



 Score = 31.9 bits (69), Expect = 1.2
 Identities = 9/21 (42%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+ ++T+WR +RG++
Sbjct: 750 EENKDEYIGLMTEWRFSRGVQ 770


>AY043361-1|AAK94668.1|  922|Homo sapiens WW domain-containing protein
            1 protein.
          Length = 922

 Score =  239 bits (585), Expect = 4e-63
 Identities = 105/139 (75%), Positives = 123/139 (88%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            ++REWFFLLSHEVLNPMYCLFEYA KNNY LQINPAS +NPDHL YF FIGRFIAMAL+H
Sbjct: 611  LAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFH 670

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            G+FI +GF++PFYKRML+KKLT+KD+ESID EFYNSL+WI+DNNI+ECGLEM+FSVD E+
Sbjct: 671  GKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEI 730

Query: 369  LGQVIHHELKPAGDKERVT 425
            LG+V  H+LK  G    VT
Sbjct: 731  LGKVTSHDLKLGGSNILVT 749



 Score = 31.9 bits (69), Expect = 1.2
 Identities = 9/21 (42%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+ ++T+WR +RG++
Sbjct: 750 EENKDEYIGLMTEWRFSRGVQ 770


>BC011571-1|AAH11571.1|  903|Homo sapiens ITCH protein protein.
          Length = 903

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 592  VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 651

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 652  GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 711

Query: 369  LGQVIHHELKPAGDKERVT 425
            LG++  H+LKP G    VT
Sbjct: 712  LGEIKSHDLKPNGGNILVT 730



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 731 EENKEEYIRMVAEWRLSRGVE 751


>AL356299-4|CAI17959.1|  903|Homo sapiens itchy homolog E3 ubiquitin
            protein ligase (mouse) protein.
          Length = 903

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 592  VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 651

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 652  GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 711

Query: 369  LGQVIHHELKPAGDKERVT 425
            LG++  H+LKP G    VT
Sbjct: 712  LGEIKSHDLKPNGGNILVT 730



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 731 EENKEEYIRMVAEWRLSRGVE 751


>AL356299-3|CAI17960.1|  862|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 862

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 551 VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 610

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 611 GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 670

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG++  H+LKP G    VT
Sbjct: 671 LGEIKSHDLKPNGGNILVT 689



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 690 EENKEEYIRMVAEWRLSRGVE 710


>AL109923-6|CAI21458.1|  903|Homo sapiens itchy homolog E3 ubiquitin
            protein ligase (mouse) protein.
          Length = 903

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 592  VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 651

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 652  GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 711

Query: 369  LGQVIHHELKPAGDKERVT 425
            LG++  H+LKP G    VT
Sbjct: 712  LGEIKSHDLKPNGGNILVT 730



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 731 EENKEEYIRMVAEWRLSRGVE 751


>AL109923-5|CAI21459.1|  862|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 862

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 551 VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 610

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 611 GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 670

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG++  H+LKP G    VT
Sbjct: 671 LGEIKSHDLKPNGGNILVT 689



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 690 EENKEEYIRMVAEWRLSRGVE 710


>AF095745-1|AAK39399.1|  862|Homo sapiens ubiquitin protein ligase
           ITCH protein.
          Length = 862

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 551 VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 610

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 611 GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 670

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG++  H+LKP G    VT
Sbjct: 671 LGEIKSHDLKPNGGNILVT 689



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 690 EENKEEYIRMVAEWRLSRGVE 710


>AF038564-1|AAC04845.1|  739|Homo sapiens atrophin-1 interacting
           protein 4 protein.
          Length = 739

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 428 VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 487

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 488 GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 547

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG++  H+LKP G    VT
Sbjct: 548 LGEIKSHDLKPNGGNILVT 566



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 567 EENKEEYIRMVAEWRLSRGVE 587


>AB209747-1|BAD92984.1|  605|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase variant protein.
          Length = 605

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 294 VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 353

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 354 GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 413

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG++  H+LKP G    VT
Sbjct: 414 LGEIKSHDLKPNGGNILVT 432



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 433 EENKEEYIRMVAEWRLSRGVE 453


>AB056663-1|BAB39389.1|  862|Homo sapiens ubiquitin protein ligase
           Itch protein.
          Length = 862

 Score =  239 bits (584), Expect = 5e-63
 Identities = 102/139 (73%), Positives = 124/139 (89%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REWFFLLSHEVLNPMYCLFEYA K+NY LQINPASY+NPDHL YF+FIGRFIAMAL+H
Sbjct: 551 VAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFH 610

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G+FI +GF++PFYKR+LNK + +KD+ESIDPEFYNSL+W+K+NNI+EC LEM+FSVD E+
Sbjct: 611 GKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEI 670

Query: 369 LGQVIHHELKPAGDKERVT 425
           LG++  H+LKP G    VT
Sbjct: 671 LGEIKSHDLKPNGGNILVT 689



 Score = 35.5 bits (78), Expect = 0.100
 Identities = 11/21 (52%), Positives = 19/21 (90%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NKE+Y+++V +WR++RG+E
Sbjct: 690 EENKEEYIRMVAEWRLSRGVE 710


>BC015380-1|AAH15380.2|  300|Homo sapiens WWP1 protein protein.
          Length = 300

 Score =  215 bits (525), Expect = 7e-56
 Identities = 95/127 (74%), Positives = 111/127 (87%)
 Frame = +3

Query: 45  VLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSGFTMPF 224
           VLNPMYCLFEYA KNNY LQINPAS +NPDHL YF FIGRFIAMAL+HG+FI +GF++PF
Sbjct: 1   VLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPF 60

Query: 225 YKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLGQVIHHELKPA 404
           YKRML+KKLT+KD+ESID EFYNSL+WI+DNNI+ECGLEM+FSVD E+LG+V  H+LK  
Sbjct: 61  YKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLG 120

Query: 405 GDKERVT 425
           G    VT
Sbjct: 121 GSNILVT 127



 Score = 31.9 bits (69), Expect = 1.2
 Identities = 9/21 (42%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+ ++T+WR +RG++
Sbjct: 128 EENKDEYIGLMTEWRFSRGVQ 148


>BC111945-1|AAI11946.1|  748|Homo sapiens SMAD specific E3 ubiquitin
           protein ligase 2 protein.
          Length = 748

 Score =  165 bits (401), Expect = 7e-41
 Identities = 71/133 (53%), Positives = 99/133 (74%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LLSHE+LNP Y LF+Y+  + Y+LQINP S VNP+HL YF F+GR + MA++H
Sbjct: 437 VAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFH 496

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K +T+ D+E +DP+ +NSLVWI +N+I    L+  F V+   
Sbjct: 497 GHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGV-LDHTFCVEHNA 555

Query: 369 LGQVIHHELKPAG 407
            G++I HELKP G
Sbjct: 556 YGEIIQHELKPNG 568



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 575 EENKKEYVRLYVNWRFLRGIE 595


>BC093876-1|AAH93876.1|  748|Homo sapiens SMAD specific E3 ubiquitin
           protein ligase 2 protein.
          Length = 748

 Score =  165 bits (401), Expect = 7e-41
 Identities = 71/133 (53%), Positives = 99/133 (74%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LLSHE+LNP Y LF+Y+  + Y+LQINP S VNP+HL YF F+GR + MA++H
Sbjct: 437 VAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFH 496

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K +T+ D+E +DP+ +NSLVWI +N+I    L+  F V+   
Sbjct: 497 GHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGV-LDHTFCVEHNA 555

Query: 369 LGQVIHHELKPAG 407
            G++I HELKP G
Sbjct: 556 YGEIIQHELKPNG 568



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 575 EENKKEYVRLYVNWRFLRGIE 595


>AY014180-1|AAG50421.1|  748|Homo sapiens E3 ubiquitin ligase Smurf2
           protein.
          Length = 748

 Score =  165 bits (401), Expect = 7e-41
 Identities = 71/133 (53%), Positives = 99/133 (74%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LLSHE+LNP Y LF+Y+  + Y+LQINP S VNP+HL YF F+GR + MA++H
Sbjct: 437 VAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFH 496

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K +T+ D+E +DP+ +NSLVWI +N+I    L+  F V+   
Sbjct: 497 GHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGV-LDHTFCVEHNA 555

Query: 369 LGQVIHHELKPAG 407
            G++I HELKP G
Sbjct: 556 YGEIIQHELKPNG 568



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 575 EENKKEYVRLYVNWRFLRGIE 595


>AF310676-1|AAG45422.1|  748|Homo sapiens E3 ubiquitin ligase SMURF2
           protein.
          Length = 748

 Score =  165 bits (401), Expect = 7e-41
 Identities = 71/133 (53%), Positives = 99/133 (74%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LLSHE+LNP Y LF+Y+  + Y+LQINP S VNP+HL YF F+GR + MA++H
Sbjct: 437 VAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFH 496

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K +T+ D+E +DP+ +NSLVWI +N+I    L+  F V+   
Sbjct: 497 GHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGV-LDHTFCVEHNA 555

Query: 369 LGQVIHHELKPAG 407
            G++I HELKP G
Sbjct: 556 YGEIIQHELKPNG 568



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 575 EENKKEYVRLYVNWRFLRGIE 595


>AF301463-1|AAG25641.1|  748|Homo sapiens ubiquitin E3 ligase SMURF2
           protein.
          Length = 748

 Score =  165 bits (401), Expect = 7e-41
 Identities = 71/133 (53%), Positives = 99/133 (74%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LLSHE+LNP Y LF+Y+  + Y+LQINP S VNP+HL YF F+GR + MA++H
Sbjct: 437 VAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFH 496

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K +T+ D+E +DP+ +NSLVWI +N+I    L+  F V+   
Sbjct: 497 GHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGV-LDHTFCVEHNA 555

Query: 369 LGQVIHHELKPAG 407
            G++I HELKP G
Sbjct: 556 YGEIIQHELKPNG 568



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 575 EENKKEYVRLYVNWRFLRGIE 595


>AF464850-1|AAM90910.1|  757|Homo sapiens Smad-ubiquitin E3 ligase
           Smurf1-beta protein.
          Length = 757

 Score =  164 bits (399), Expect = 1e-40
 Identities = 71/139 (51%), Positives = 98/139 (70%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LL HE+LNP Y LF+Y+  N Y LQINP S +NPDHL YF F+GR + +A++H
Sbjct: 443 VAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFH 502

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K + + D+ES+DPE + SLVWI +N+I    L+  F V+   
Sbjct: 503 GHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPV-LDHTFCVEHNA 561

Query: 369 LGQVIHHELKPAGDKERVT 425
            G+++ HELKP G    VT
Sbjct: 562 FGRILQHELKPNGRNVPVT 580



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 581 EENKKEYVRLYVNWRFMRGIE 601


>AF199364-1|AAF08298.2|  722|Homo sapiens E3 ubiquitin ligase SMURF1
           protein.
          Length = 722

 Score =  164 bits (399), Expect = 1e-40
 Identities = 71/139 (51%), Positives = 98/139 (70%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LL HE+LNP Y LF+Y+  N Y LQINP S +NPDHL YF F+GR + +A++H
Sbjct: 408 VAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFH 467

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K + + D+ES+DPE + SLVWI +N+I    L+  F V+   
Sbjct: 468 GHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPV-LDHTFCVEHNA 526

Query: 369 LGQVIHHELKPAGDKERVT 425
            G+++ HELKP G    VT
Sbjct: 527 FGRILQHELKPNGRNVPVT 545



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 546 EENKKEYVRLYVNWRFMRGIE 566


>AC004893-2|AAC62434.1|  712|Homo sapiens WUGSC:H_DJ0808A01.2
           protein.
          Length = 712

 Score =  164 bits (399), Expect = 1e-40
 Identities = 71/139 (51%), Positives = 98/139 (70%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LL HE+LNP Y LF+Y+  N Y LQINP S +NPDHL YF F+GR + +A++H
Sbjct: 398 VAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFH 457

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K + + D+ES+DPE + SLVWI +N+I    L+  F V+   
Sbjct: 458 GHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPV-LDHTFCVEHNA 516

Query: 369 LGQVIHHELKPAGDKERVT 425
            G+++ HELKP G    VT
Sbjct: 517 FGRILQHELKPNGRNVPVT 535



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 536 EENKKEYVRLYVNWRFMRGIE 556


>AB046845-1|BAB13451.1|  859|Homo sapiens KIAA1625 protein protein.
          Length = 859

 Score =  164 bits (399), Expect = 1e-40
 Identities = 71/139 (51%), Positives = 98/139 (70%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V+REW +LL HE+LNP Y LF+Y+  N Y LQINP S +NPDHL YF F+GR + +A++H
Sbjct: 545 VAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFH 604

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
           G +I  GFT+PFYK++L K + + D+ES+DPE + SLVWI +N+I    L+  F V+   
Sbjct: 605 GHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPV-LDHTFCVEHNA 663

Query: 369 LGQVIHHELKPAGDKERVT 425
            G+++ HELKP G    VT
Sbjct: 664 FGRILQHELKPNGRNVPVT 682



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 683 EENKKEYVRLYVNWRFMRGIE 703


>D42055-1|BAA07655.1|  927|Homo sapiens KIAA0093 protein.
          Length = 927

 Score =  155 bits (375), Expect = 1e-37
 Identities = 75/140 (53%), Positives = 97/140 (69%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFL+S E+ NP Y LFEY+  +NY+LQINP S + N DHL YFKFIGR   MA+Y
Sbjct: 615  VAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVY 674

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML+K +T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 675  HGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILEN--DPTELDLRFIIDEE 732

Query: 366  VLGQVIHHELKPAGDKERVT 425
            + GQ   HELK  G +  VT
Sbjct: 733  LFGQTHQHELKNGGSEIVVT 752


>AY550969-1|AAT52215.1|  900|Homo sapiens cell proliferation-inducing
            protein 53 protein.
          Length = 900

 Score =  155 bits (375), Expect = 1e-37
 Identities = 75/140 (53%), Positives = 97/140 (69%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFL+S E+ NP Y LFEY+  +NY+LQINP S + N DHL YFKFIGR   MA+Y
Sbjct: 588  VAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVY 647

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML+K +T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 648  HGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILEN--DPTELDLRFIIDEE 705

Query: 366  VLGQVIHHELKPAGDKERVT 425
            + GQ   HELK  G +  VT
Sbjct: 706  LFGQTHQHELKNGGSEIVVT 725


>DQ181796-1|ABA10330.1|  834|Homo sapiens NEDD4L variant protein.
          Length = 834

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 522 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 581

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 582 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 639

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 640 NFGQTYQVDLKPNGSEIMVT 659


>BC032597-1|AAH32597.1|  911|Homo sapiens NEDD4L protein protein.
          Length = 911

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 599  VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 658

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 659  HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 716

Query: 366  VLGQVIHHELKPAGDKERVT 425
              GQ    +LKP G +  VT
Sbjct: 717  NFGQTYQVDLKPNGSEIMVT 736


>BC019345-1|AAH19345.1|  855|Homo sapiens Unknown (protein for
           IMAGE:3604024) protein.
          Length = 855

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 543 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 602

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 603 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 660

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 661 NFGQTYQVDLKPNGSEIMVT 680


>BC000621-1|AAH00621.2|  855|Homo sapiens NEDD4L protein protein.
          Length = 855

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 543 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 602

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 603 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 660

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 661 NFGQTYQVDLKPNGSEIMVT 680


>AY312514-1|AAP75706.1|  975|Homo sapiens NEDD4.2 protein.
          Length = 975

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 663  VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 722

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 723  HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 780

Query: 366  VLGQVIHHELKPAGDKERVT 425
              GQ    +LKP G +  VT
Sbjct: 781  NFGQTYQVDLKPNGSEIMVT 800


>AY112985-1|AAM76730.1|  947|Homo sapiens ubiquitin ligase NEDD4h
            protein.
          Length = 947

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 635  VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 694

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 695  HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 752

Query: 366  VLGQVIHHELKPAGDKERVT 425
              GQ    +LKP G +  VT
Sbjct: 753  NFGQTYQVDLKPNGSEIMVT 772


>AY112984-1|AAM76729.1|  967|Homo sapiens ubiquitin ligase NEDD4g
            protein.
          Length = 967

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 655  VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 714

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 715  HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 772

Query: 366  VLGQVIHHELKPAGDKERVT 425
              GQ    +LKP G +  VT
Sbjct: 773  NFGQTYQVDLKPNGSEIMVT 792


>AY112983-1|AAM76728.1|  854|Homo sapiens ubiquitin ligase NEDD4f
           protein.
          Length = 854

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 542 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 601

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 602 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 659

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 660 NFGQTYQVDLKPNGSEIMVT 679


>AL137469-1|CAB70754.1|  820|Homo sapiens hypothetical protein
           protein.
          Length = 820

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 508 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 567

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 568 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 625

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 626 NFGQTYQVDLKPNGSEIMVT 645


>AF385931-1|AAM46208.1|  854|Homo sapiens ubiquitin ligase NEDD4Lb
           protein.
          Length = 854

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 542 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 601

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 602 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 659

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 660 NFGQTYQVDLKPNGSEIMVT 679


>AF210730-1|AAG43524.1|  854|Homo sapiens NEDD4La protein.
          Length = 854

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
           V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 542 VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 601

Query: 186 HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
           HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 602 HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 659

Query: 366 VLGQVIHHELKPAGDKERVT 425
             GQ    +LKP G +  VT
Sbjct: 660 NFGQTYQVDLKPNGSEIMVT 679


>AB071179-1|BAB69424.1|  955|Homo sapiens NEDD4-like ubiquitin ligase
            3 protein.
          Length = 955

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 643  VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 702

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 703  HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 760

Query: 366  VLGQVIHHELKPAGDKERVT 425
              GQ    +LKP G +  VT
Sbjct: 761  NFGQTYQVDLKPNGSEIMVT 780


>AB007899-1|BAA23711.1|  995|Homo sapiens KIAA0439 protein.
          Length = 995

 Score =  150 bits (363), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 95/140 (67%), Gaps = 1/140 (0%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYV-NPDHLLYFKFIGRFIAMALY 185
            V+REWFFLLS E+ NP Y LFEY+  +NY+LQINP S + N DHL YF FIGR   +A++
Sbjct: 683  VAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVF 742

Query: 186  HGRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFE 365
            HG+ +   F  PFYK ML K++T+ D+ES+D E+YNSL WI +N  D   L++ F +D E
Sbjct: 743  HGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEN--DPTELDLMFCIDEE 800

Query: 366  VLGQVIHHELKPAGDKERVT 425
              GQ    +LKP G +  VT
Sbjct: 801  NFGQTYQVDLKPNGSEIMVT 820


>BC151227-1|AAI51228.1| 1606|Homo sapiens HECT, C2 and WW domain
            containing E3 ubiquitin protein ligase 1 protein.
          Length = 1606

 Score =  132 bits (318), Expect = 8e-31
 Identities = 64/138 (46%), Positives = 90/138 (65%)
 Frame = +3

Query: 12   SREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHG 191
            SRE+FFLLS E+ NP Y LFEY+  + Y++QI+P S    +HL +F+F GR + +AL H 
Sbjct: 1296 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ 1355

Query: 192  RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVL 371
              + + FT PFYK +L     + D+E +D EF+ SL W+KDNNI +  L++ F+V+ EV 
Sbjct: 1356 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDI-LDLTFTVNEEVF 1414

Query: 372  GQVIHHELKPAGDKERVT 425
            GQV   ELK  G   +VT
Sbjct: 1415 GQVTERELKSGGANTQVT 1432


>AB048365-1|BAB13352.1| 1585|Homo sapiens NEDD4-like ubiquitin ligase
            1 protein.
          Length = 1585

 Score =  132 bits (318), Expect = 8e-31
 Identities = 64/138 (46%), Positives = 90/138 (65%)
 Frame = +3

Query: 12   SREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHG 191
            SRE+FFLLS E+ NP Y LFEY+  + Y++QI+P S    +HL +F+F GR + +AL H 
Sbjct: 1275 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ 1334

Query: 192  RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVL 371
              + + FT PFYK +L     + D+E +D EF+ SL W+KDNNI +  L++ F+V+ EV 
Sbjct: 1335 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDI-LDLTFTVNEEVF 1393

Query: 372  GQVIHHELKPAGDKERVT 425
            GQV   ELK  G   +VT
Sbjct: 1394 GQVTERELKSGGANTQVT 1411


>AB002320-1|BAA20780.2| 1614|Homo sapiens KIAA0322 protein.
          Length = 1614

 Score =  132 bits (318), Expect = 8e-31
 Identities = 64/138 (46%), Positives = 90/138 (65%)
 Frame = +3

Query: 12   SREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHG 191
            SRE+FFLLS E+ NP Y LFEY+  + Y++QI+P S    +HL +F+F GR + +AL H 
Sbjct: 1304 SREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQ 1363

Query: 192  RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVL 371
              + + FT PFYK +L     + D+E +D EF+ SL W+KDNNI +  L++ F+V+ EV 
Sbjct: 1364 YLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDI-LDLTFTVNEEVF 1422

Query: 372  GQVIHHELKPAGDKERVT 425
            GQV   ELK  G   +VT
Sbjct: 1423 GQVTERELKSGGANTQVT 1440


>BC009527-1|AAH09527.1|  288|Homo sapiens SMURF2 protein protein.
          Length = 288

 Score =  128 bits (309), Expect = 1e-29
 Identities = 55/105 (52%), Positives = 77/105 (73%)
 Frame = +3

Query: 93  YSLQINPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTMKDIES 272
           Y+LQINP S VNP+HL YF F+GR + MA++HG +I  GFT+PFYK++L K +T+ D+E 
Sbjct: 5   YTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMEL 64

Query: 273 IDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLGQVIHHELKPAG 407
           +DP+ +NSLVWI +N+I    L+  F V+    G++I HELKP G
Sbjct: 65  VDPDLHNSLVWILENDITGV-LDHTFCVEHNAYGEIIQHELKPNG 108



 Score = 29.5 bits (63), Expect = 6.5
 Identities = 10/21 (47%), Positives = 15/21 (71%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           E NK++Y+++   WR  RGIE
Sbjct: 115 EENKKEYVRLYVNWRFLRGIE 135


>BC034982-1|AAH34982.1|  909|Homo sapiens HECT domain and ankyrin
            repeat containing, E3 ubiquitin protein ligase 1 protein.
          Length = 909

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 596  VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 654

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
             + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 655  RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 714

Query: 369  LGQVIHHELKPAGDKERVT 425
             G +    LKP G    VT
Sbjct: 715  FGAMEEVPLKPGGGSILVT 733



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 734 QNNKAEYVQLVTELRMTRAIQ 754


>AL590402-2|CAH74024.1|  903|Homo sapiens HECT domain and ankyrin
            repeat containing, E3 ubiquitin protein ligase 1 protein.
          Length = 903

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 590  VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 648

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
             + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 649  RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 708

Query: 369  LGQVIHHELKPAGDKERVT 425
             G +    LKP G    VT
Sbjct: 709  FGAMEEVPLKPGGGSILVT 727



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 728 QNNKAEYVQLVTELRMTRAIQ 748


>AL590402-1|CAH74023.1|  562|Homo sapiens HECT domain and ankyrin
           repeat containing, E3 ubiquitin protein ligase 1
           protein.
          Length = 562

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 249 VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 307

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 308 RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 367

Query: 369 LGQVIHHELKPAGDKERVT 425
            G +    LKP G    VT
Sbjct: 368 FGAMEEVPLKPGGGSILVT 386



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 387 QNNKAEYVQLVTELRMTRAIQ 407


>AL513472-2|CAH71890.1|  903|Homo sapiens HECT domain and ankyrin
            repeat containing, E3 ubiquitin protein ligase 1 protein.
          Length = 903

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 590  VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 648

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
             + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 649  RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 708

Query: 369  LGQVIHHELKPAGDKERVT 425
             G +    LKP G    VT
Sbjct: 709  FGAMEEVPLKPGGGSILVT 727



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 728 QNNKAEYVQLVTELRMTRAIQ 748


>AL513472-1|CAH71889.1|  562|Homo sapiens HECT domain and ankyrin
           repeat containing, E3 ubiquitin protein ligase 1
           protein.
          Length = 562

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 249 VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 307

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 308 RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 367

Query: 369 LGQVIHHELKPAGDKERVT 425
            G +    LKP G    VT
Sbjct: 368 FGAMEEVPLKPGGGSILVT 386



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 387 QNNKAEYVQLVTELRMTRAIQ 407


>AL357315-1|CAI16815.1|  903|Homo sapiens HECT domain and ankyrin
            repeat containing, E3 ubiquitin protein ligase 1 protein.
          Length = 903

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 590  VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 648

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
             + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 649  RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 708

Query: 369  LGQVIHHELKPAGDKERVT 425
             G +    LKP G    VT
Sbjct: 709  FGAMEEVPLKPGGGSILVT 727



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 728 QNNKAEYVQLVTELRMTRAIQ 748


>AB037741-1|BAA92558.1|  567|Homo sapiens KIAA1320 protein protein.
          Length = 567

 Score =  126 bits (305), Expect = 3e-29
 Identities = 62/139 (44%), Positives = 87/139 (62%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V REWF +LS+E++NP Y LF  +  +  + Q N  SYVNPDHL YF+F G+ + +AL H
Sbjct: 254 VVREWFDILSNEIVNPDYALFTQS-ADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNH 312

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
            + +   FT  FYK +L   +  +D+ SIDPE+  +L WI DN+I + GLE+ FSV+ +V
Sbjct: 313 RQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDV 372

Query: 369 LGQVIHHELKPAGDKERVT 425
            G +    LKP G    VT
Sbjct: 373 FGAMEEVPLKPGGGSILVT 391



 Score = 29.9 bits (64), Expect = 4.9
 Identities = 11/21 (52%), Positives = 18/21 (85%)
 Frame = +1

Query: 427 ESNKEQYLQVVTQWRMTRGIE 489
           ++NK +Y+Q+VT+ RMTR I+
Sbjct: 392 QNNKAEYVQLVTELRMTRAIQ 412


>BC117198-1|AAI17199.1| 1572|Homo sapiens HECT, C2 and WW domain
            containing E3 ubiquitin protein ligase 2 protein.
          Length = 1572

 Score =  126 bits (303), Expect = 5e-29
 Identities = 61/138 (44%), Positives = 89/138 (64%)
 Frame = +3

Query: 12   SREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHG 191
            SRE+FFL+S E+ NP Y LFEY+  + Y++QI+P S    +H  +F+F GR + +AL H 
Sbjct: 1262 SREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQ 1321

Query: 192  RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVL 371
              + + FT PFYK +L     + D+E +D EF+ SL W+KDN+I +  L++ F+V+ EV 
Sbjct: 1322 YLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDI-LDLTFTVNEEVF 1380

Query: 372  GQVIHHELKPAGDKERVT 425
            GQ+   ELKP G    VT
Sbjct: 1381 GQITERELKPGGANIPVT 1398


>BC117194-1|AAI17195.1| 1572|Homo sapiens HECT, C2 and WW domain
            containing E3 ubiquitin protein ligase 2 protein.
          Length = 1572

 Score =  126 bits (303), Expect = 5e-29
 Identities = 61/138 (44%), Positives = 89/138 (64%)
 Frame = +3

Query: 12   SREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHG 191
            SRE+FFL+S E+ NP Y LFEY+  + Y++QI+P S    +H  +F+F GR + +AL H 
Sbjct: 1262 SREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQ 1321

Query: 192  RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVL 371
              + + FT PFYK +L     + D+E +D EF+ SL W+KDN+I +  L++ F+V+ EV 
Sbjct: 1322 YLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDI-LDLTFTVNEEVF 1380

Query: 372  GQVIHHELKPAGDKERVT 425
            GQ+   ELKP G    VT
Sbjct: 1381 GQITERELKPGGANIPVT 1398


>AB037722-1|BAA92539.1| 1581|Homo sapiens KIAA1301 protein protein.
          Length = 1581

 Score =  126 bits (303), Expect = 5e-29
 Identities = 61/138 (44%), Positives = 89/138 (64%)
 Frame = +3

Query: 12   SREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHG 191
            SRE+FFL+S E+ NP Y LFEY+  + Y++QI+P S    +H  +F+F GR + +AL H 
Sbjct: 1271 SREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQ 1330

Query: 192  RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVL 371
              + + FT PFYK +L     + D+E +D EF+ SL W+KDN+I +  L++ F+V+ EV 
Sbjct: 1331 YLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDI-LDLTFTVNEEVF 1389

Query: 372  GQVIHHELKPAGDKERVT 425
            GQ+   ELKP G    VT
Sbjct: 1390 GQITERELKPGGANIPVT 1407


>Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 3407

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 3096 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 3155

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 3156 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 3215

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 3216 VCEVRDLKPNGANILVT 3232


>Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 4374

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 4063 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 4122

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 4123 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 4182

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 4183 VCEVRDLKPNGANILVT 4199


>Z97054-1|CAI42644.1| 1196|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 1196

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 885  REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 944

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 945  LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 1004

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 1005 VCEVRDLKPNGANILVT 1021


>Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 4374

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 4063 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 4122

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 4123 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 4182

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 4183 VCEVRDLKPNGANILVT 4199


>DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase
            protein.
          Length = 4374

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 4063 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 4122

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 4123 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 4182

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 4183 VCEVRDLKPNGANILVT 4199


>BC107576-1|AAI07577.1|  332|Homo sapiens HUWE1 protein protein.
          Length = 332

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
           REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 21  REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 80

Query: 195 FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
            +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 81  LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 140

Query: 375 QVIHHELKPAGDKERVT 425
                +LKP G    VT
Sbjct: 141 VCEVRDLKPNGANILVT 157


>BC063505-1|AAH63505.1|  388|Homo sapiens HUWE1 protein protein.
          Length = 388

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
           REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 77  REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 136

Query: 195 FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
            +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 137 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 196

Query: 375 QVIHHELKPAGDKERVT 425
                +LKP G    VT
Sbjct: 197 VCEVRDLKPNGANILVT 213


>BC002602-1|AAH02602.2|  442|Homo sapiens HUWE1 protein protein.
          Length = 442

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
           REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 131 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 190

Query: 195 FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
            +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 191 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 250

Query: 375 QVIHHELKPAGDKERVT 425
                +LKP G    VT
Sbjct: 251 VCEVRDLKPNGANILVT 267


>AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.
          Length = 4374

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 4063 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 4122

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 4123 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 4182

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 4183 VCEVRDLKPNGANILVT 4199


>AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1
            protein.
          Length = 4374

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 4063 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 4122

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 4123 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 4182

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 4183 VCEVRDLKPNGANILVT 4199


>AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 3407

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 3096 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 3155

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 3156 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 3215

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 3216 VCEVRDLKPNGANILVT 3232


>AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 4374

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 4063 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 4122

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 4123 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 4182

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 4183 VCEVRDLKPNGANILVT 4199


>AL592046-1|CAI39578.1| 1196|Homo sapiens upstream regulatory element
            binding protein 1 (UREB1) protein.
          Length = 1196

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 885  REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 944

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 945  LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 1004

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 1005 VCEVRDLKPNGANILVT 1021


>AK223167-1|BAD96887.1|  439|Homo sapiens E3 ubiquitin protein
           ligase URE-B1 variant protein.
          Length = 439

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
           REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 128 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 187

Query: 195 FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
            +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 188 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 247

Query: 375 QVIHHELKPAGDKERVT 425
                +LKP G    VT
Sbjct: 248 VCEVRDLKPNGANILVT 264


>AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LASU1
            protein.
          Length = 3360

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 3049 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 3108

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 3109 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 3168

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 3169 VCEVRDLKPNGANILVT 3185


>AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.
          Length = 3192

 Score =  122 bits (293), Expect = 9e-28
 Identities = 55/137 (40%), Positives = 82/137 (59%)
 Frame = +3

Query: 15   REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGR 194
            REW+ ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R
Sbjct: 2881 REWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNR 2940

Query: 195  FIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLG 374
             +   FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G
Sbjct: 2941 LLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFG 3000

Query: 375  QVIHHELKPAGDKERVT 425
                 +LKP G    VT
Sbjct: 3001 VCEVRDLKPNGANILVT 3017


>CR456813-1|CAG33094.1|  308|Homo sapiens UREB1 protein.
          Length = 308

 Score =  112 bits (269), Expect = 7e-25
 Identities = 52/132 (39%), Positives = 78/132 (59%)
 Frame = +3

Query: 30  LLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSG 209
           ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R +   
Sbjct: 2   IISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECY 61

Query: 210 FTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLGQVIHH 389
           FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G     
Sbjct: 62  FTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVR 121

Query: 390 ELKPAGDKERVT 425
           +LKP G    VT
Sbjct: 122 DLKPNGANILVT 133


>AF057569-1|AAC62492.1|  308|Homo sapiens upstream regulatory
           element binding protein 1 protein.
          Length = 308

 Score =  112 bits (269), Expect = 7e-25
 Identities = 52/132 (39%), Positives = 78/132 (59%)
 Frame = +3

Query: 30  LLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSG 209
           ++S E+ NPMY LF  +  +  +  INP+S+ NP+HL YFKF+GR +A A+Y  R +   
Sbjct: 2   IISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNHLSYFKFVGRIVAKAVYDNRLLECY 61

Query: 210 FTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEVLGQVIHH 389
           FT  FYK +L K +   D+ES D  FY  LV++ +N++   G ++ FS + +  G     
Sbjct: 62  FTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVCEVR 121

Query: 390 ELKPAGDKERVT 425
           +LKP G    VT
Sbjct: 122 DLKPNGANILVT 133


>BX537403-1|CAD97645.1| 1068|Homo sapiens hypothetical protein
            protein.
          Length = 1068

 Score = 66.1 bits (154), Expect = 6e-11
 Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+   +   V +P   LF+     +  L  +P SY++ ++L  F+F+G+ +  A+Y 
Sbjct: 730  VFKEFLEEIIKRVFDPALNLFK-TTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYE 788

Query: 189  GRFIYSGFTMPFYKRMLNKK-----LTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFS 353
            G  +   F   F  ++L         ++ ++ S+D EFY +L  IK  + D   L +  S
Sbjct: 789  GIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLS 848

Query: 354  VDFEVLGQVIHHELKPAGDKERVT 425
             D +V+GQ++ HEL P G    VT
Sbjct: 849  YDEDVMGQLVCHELIPGGKTIPVT 872


>BC141880-1|AAI41881.1| 1068|Homo sapiens ubiquitin protein ligase E3B
            protein.
          Length = 1068

 Score = 66.1 bits (154), Expect = 6e-11
 Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+   +   V +P   LF+     +  L  +P SY++ ++L  F+F+G+ +  A+Y 
Sbjct: 730  VFKEFLEEIIKRVFDPALNLFK-TTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYE 788

Query: 189  GRFIYSGFTMPFYKRMLNKK-----LTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFS 353
            G  +   F   F  ++L         ++ ++ S+D EFY +L  IK  + D   L +  S
Sbjct: 789  GIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLS 848

Query: 354  VDFEVLGQVIHHELKPAGDKERVT 425
             D +V+GQ++ HEL P G    VT
Sbjct: 849  YDEDVMGQLVCHELIPGGKTIPVT 872


>BC032301-1|AAH32301.1| 1026|Homo sapiens UBE3B protein protein.
          Length = 1026

 Score = 66.1 bits (154), Expect = 6e-11
 Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+   +   V +P   LF+     +  L  +P SY++ ++L  F+F+G+ +  A+Y 
Sbjct: 730  VFKEFLEEIIKRVFDPALNLFK-TTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYE 788

Query: 189  GRFIYSGFTMPFYKRMLNKK-----LTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFS 353
            G  +   F   F  ++L         ++ ++ S+D EFY +L  IK  + D   L +  S
Sbjct: 789  GIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLS 848

Query: 354  VDFEVLGQVIHHELKPAGDKERVT 425
             D +V+GQ++ HEL P G    VT
Sbjct: 849  YDEDVMGQLVCHELIPGGKTIPVT 872


>AF251046-1|AAK28419.2| 1068|Homo sapiens UBE3B variant 1 protein.
          Length = 1068

 Score = 66.1 bits (154), Expect = 6e-11
 Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+   +   V +P   LF+     +  L  +P SY++ ++L  F+F+G+ +  A+Y 
Sbjct: 730  VFKEFLEEIIKRVFDPALNLFK-TTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYE 788

Query: 189  GRFIYSGFTMPFYKRMLNKK-----LTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFS 353
            G  +   F   F  ++L         ++ ++ S+D EFY +L  IK  + D   L +  S
Sbjct: 789  GIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLS 848

Query: 354  VDFEVLGQVIHHELKPAGDKERVT 425
             D +V+GQ++ HEL P G    VT
Sbjct: 849  YDEDVMGQLVCHELIPGGKTIPVT 872


>X98033-1|CAA66656.1|  852|Homo sapiens E6-AP protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>X98032-1|CAA66655.1|  852|Homo sapiens E6-AP protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>X98031-1|CAA66654.1|  852|Homo sapiens E6-AP protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>X98021-1|CAA66653.1|  852|Homo sapiens E6-AP protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>U84404-1|AAB49301.1|  852|Homo sapiens E6-associated protein
           E6-AP/ubiquitin-protein ligase protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
          Length = 1054

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V++E+F LL  E+LNP+Y +F Y   +N  L  +   +V  +   +F  IG    +A+Y+
Sbjct: 750  VTKEFFLLLLKELLNPIYGMFTYYQDSNL-LWFSDTCFVEHN---WFHLIGITCGLAIYN 805

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD---NNIDECGLEMWFSVD 359
               +   F +  YK++LN K  ++D++ + P    SL  + D    +++E    + F++ 
Sbjct: 806  STVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEET-FCLNFTIC 864

Query: 360  FEVLGQVIHHELKPAGDKERV 422
             E  G +   +L P GD   V
Sbjct: 865  RESYGVIEQKKLIPGGDNVTV 885


>BC009271-1|AAH09271.1|  585|Homo sapiens UBE3A protein protein.
          Length = 585

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 280 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 335

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 336 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 395

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 396 DLFGNPMMYDLKENGDKIPIT 416


>BC002582-1|AAH02582.2|  872|Homo sapiens ubiquitin protein ligase
           E3A (human papilloma virus E6-associated protein, Ange
           protein.
          Length = 872

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 567 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 622

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 623 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 682

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 683 DLFGNPMMYDLKENGDKIPIT 703


>AF273050-1|AAG34910.1|  852|Homo sapiens CTCL tumor antigen se37-2
           protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>AF016708-1|AAB69154.1|  852|Homo sapiens E6-AP ubiquitin-protein
           ligase protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>AB194232-2|BAD69554.1|  852|Homo sapiens ubiquitin ligase E3A
           isoform 1 protein.
          Length = 852

 Score = 57.6 bits (133), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 547 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 602

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSL--VWIKDNNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK T +D+    P  Y SL  +   + N+++  +  +     
Sbjct: 603 NCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQT 662

Query: 363 EVLGQVIHHELKPAGDKERVT 425
           ++ G  + ++LK  GDK  +T
Sbjct: 663 DLFGNPMMYDLKENGDKIPIT 683


>L07557-1|AAA35542.1|  874|Homo sapiens oncogenic protein-associated
           protein protein.
          Length = 874

 Score = 52.8 bits (121), Expect = 6e-07
 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 2/141 (1%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS+E+F L+  E+ NP   +F Y +++      NP+S+        F  IG  + +A+Y+
Sbjct: 569 VSKEFFQLVVEEIFNPDIGMFTY-DESTKLFWFNPSSFETEGQ---FTLIGIVLGLAIYN 624

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD--NNIDECGLEMWFSVDF 362
              +   F M  Y++++ KK    D+    P  Y SL  + +   N+++  +  +     
Sbjct: 625 NCILDVHFPMVVYRKLMGKKGLFVDLGDSHPVLYQSLKDLLEYVGNVEDDMMITFQISQT 684

Query: 363 EVLGQVIHHELKPAGDKERVT 425
            + G  + ++LK  GDK  +T
Sbjct: 685 NLFGNPMMYDLKENGDKIPIT 705


>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
            protein.
          Length = 1049

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 745  VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 800

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
               +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 801  CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 858


>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
            protein 4 isoform 1 protein.
          Length = 1057

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 753  VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 808

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
               +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 809  CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 866


>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
            protein.
          Length = 1049

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 745  VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 800

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
               +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 801  CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 858


>AL356741-1|CAH74146.1|  907|Homo sapiens hect domain and RLD 4
           protein.
          Length = 907

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 603 VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 658

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
              +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 659 CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 716


>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
            protein.
          Length = 1049

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 745  VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 800

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
               +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 801  CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 858


>AL133551-1|CAI16031.1|  907|Homo sapiens hect domain and RLD 4
           protein.
          Length = 907

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 603 VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 658

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
              +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 659 CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 716


>AB046813-1|BAB13419.1|  953|Homo sapiens KIAA1593 protein protein.
          Length = 953

 Score = 50.8 bits (116), Expect = 2e-06
 Identities = 30/120 (25%), Positives = 62/120 (51%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           V +E+F L+  E+L+P Y +F Y   +   +  +  ++ + D    F  IG    +A+Y+
Sbjct: 649 VRKEFFLLIMRELLDPKYGMFRYYEDSRL-IWFSDKTFEDSD---LFHLIGVICGLAIYN 704

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
              +   F +  YK++L KK ++ D++ + P+   S+  + D   D+  +E  F ++F +
Sbjct: 705 CTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDD--IEETFCLNFTI 762


>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
            protein.
          Length = 1022

 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 30/109 (27%), Positives = 53/109 (48%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            VS E+F  +  E+  P Y +F Y      S    PA    P+   YF F G    ++L++
Sbjct: 716  VSSEFFHCMFEEMTKPEYGMFMYPEMG--SCMWFPAK-PKPEKKRYFLF-GMLCGLSLFN 771

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECG 335
                   F +  YK++L++K +++D++ + P    SL  + D+  D+ G
Sbjct: 772  LNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIG 820


>BC035775-1|AAH35775.2|  396|Homo sapiens HERC6 protein protein.
          Length = 396

 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 30/109 (27%), Positives = 53/109 (48%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS E+F  +  E+  P Y +F Y      S    PA    P+   YF F G    ++L++
Sbjct: 90  VSSEFFHCMFEEMTKPEYGMFMYPEMG--SCMWFPAK-PKPEKKRYFLF-GMLCGLSLFN 145

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECG 335
                  F +  YK++L++K +++D++ + P    SL  + D+  D+ G
Sbjct: 146 LNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIG 194


>AY653201-1|AAV66895.1|  986|Homo sapiens HERC6 splice variant
           protein.
          Length = 986

 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 30/109 (27%), Positives = 53/109 (48%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS E+F  +  E+  P Y +F Y      S    PA    P+   YF F G    ++L++
Sbjct: 680 VSSEFFHCMFEEMTKPEYGMFMYPEMG--SCMWFPAK-PKPEKKRYFLF-GMLCGLSLFN 735

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECG 335
                  F +  YK++L++K +++D++ + P    SL  + D+  D+ G
Sbjct: 736 LNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIG 784


>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
          Length = 1022

 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 30/109 (27%), Positives = 53/109 (48%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            VS E+F  +  E+  P Y +F Y      S    PA    P+   YF F G    ++L++
Sbjct: 716  VSSEFFHCMFEEMTKPEYGMFMYPEMG--SCMWFPAK-PKPEKKRYFLF-GMLCGLSLFN 771

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECG 335
                   F +  YK++L++K +++D++ + P    SL  + D+  D+ G
Sbjct: 772  LNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIG 820


>AC004975-1|AAD51453.1|  415|Homo sapiens unknown protein.
          Length = 415

 Score = 47.2 bits (107), Expect = 3e-05
 Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 6/145 (4%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASY--VNPDHLLYFKFIGRFIAMAL 182
           + RE+   L     NP    F+  N+    L  NPA+   V      ++ F+GR +  AL
Sbjct: 104 IFREFLNELLKSGFNPNQGFFKTTNEG--LLYPNPAAQMLVGDSFARHYYFLGRMLGKAL 161

Query: 183 YHGRFIYSGFTMPFYKRMLNKK--LTMKDIESIDPEFYNSLVWIK--DNNIDECGLEMWF 350
           Y    +   F   F  ++L     + +  + S+DPE Y +L+++K  +++++E GL   F
Sbjct: 162 YENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLN--F 219

Query: 351 SVDFEVLGQVIHHELKPAGDKERVT 425
           +V    LG+    ELK  G    VT
Sbjct: 220 TVVNNDLGEAQVVELKFGGKDIPVT 244


>AK000644-1|BAA91303.1|  379|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20637 fis, clone KAT03212. ).
          Length = 379

 Score = 46.4 bits (105), Expect = 5e-05
 Identities = 30/109 (27%), Positives = 53/109 (48%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           VS E+F  +  E+  P Y +F Y      S    PA    P+   YF F G    ++L++
Sbjct: 73  VSSEFFHCMFEEMTKPEYGMFMYPEM--CSCMWFPAK-PKPEKKRYFLF-GMLCGLSLFN 128

Query: 189 GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECG 335
                  F +  YK++L++K +++D++ + P    SL  + D+  D+ G
Sbjct: 129 LNVANLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQEVLDDAADDIG 177


>BC032944-1|AAH32944.1|  789|Homo sapiens KIAA0317 protein protein.
          Length = 789

 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLY--FKFIGRFIAMALYH 188
           REWF L+   + +    LF   + NN +L ++P     P HL    ++F GR +   LY 
Sbjct: 508 REWFELICKALFDTTNQLFTRFSDNNQAL-VHPNPN-RPAHLRLKMYEFAGRLVGKCLYE 565

Query: 189 G-------RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLV-WIKDNNIDECGL 338
                   + + + FT  F  +++  ++  K  E+ DPEFY S V +I +N++ E  L
Sbjct: 566 SSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMEL 623


>AC007956-1|AAF61276.1|  823|Homo sapiens KIAA0317 protein.
          Length = 823

 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLY--FKFIGRFIAMALYH 188
           REWF L+   + +    LF   + NN +L ++P     P HL    ++F GR +   LY 
Sbjct: 508 REWFELICKALFDTTNQLFTRFSDNNQAL-VHPNPN-RPAHLRLKMYEFAGRLVGKCLYE 565

Query: 189 G-------RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLV-WIKDNNIDECGL 338
                   + + + FT  F  +++  ++  K  E+ DPEFY S V +I +N++ E  L
Sbjct: 566 SSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMEL 623


>AB002315-1|BAA20775.2|  826|Homo sapiens KIAA0317 protein.
          Length = 826

 Score = 46.0 bits (104), Expect = 7e-05
 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 10/118 (8%)
 Frame = +3

Query: 15  REWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLY--FKFIGRFIAMALYH 188
           REWF L+   + +    LF   + NN +L ++P     P HL    ++F GR +   LY 
Sbjct: 511 REWFELICKALFDTTNQLFTRFSDNNQAL-VHPNPN-RPAHLRLKMYEFAGRLVGKCLYE 568

Query: 189 G-------RFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLV-WIKDNNIDECGL 338
                   + + + FT  F  +++  ++  K  E+ DPEFY S V +I +N++ E  L
Sbjct: 569 SSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMEL 626


>AL834183-1|CAD38880.1|  523|Homo sapiens hypothetical protein
           protein.
          Length = 523

 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 24/80 (30%), Positives = 44/80 (55%)
 Frame = +3

Query: 78  ANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTM 257
           AN++ Y L  +PA+   P H   F+F+G  + +A+  G  +      P +K++    LT+
Sbjct: 202 ANRDCYLL--SPAARA-PVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTI 258

Query: 258 KDIESIDPEFYNSLVWIKDN 317
            D+  +D +F   L++I+DN
Sbjct: 259 ADLSEVDKDFIPGLMYIRDN 278


>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
          Length = 4834

 Score = 45.6 bits (103), Expect = 9e-05
 Identities = 24/80 (30%), Positives = 44/80 (55%)
 Frame = +3

Query: 78   ANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTM 257
            AN++ Y L  +PA+   P H   F+F+G  + +A+  G  +      P +K++    LT+
Sbjct: 4513 ANRDCYLL--SPAARA-PVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTI 4569

Query: 258  KDIESIDPEFYNSLVWIKDN 317
             D+  +D +F   L++I+DN
Sbjct: 4570 ADLSEVDKDFIPGLMYIRDN 4589


>D13635-1|BAA02799.2| 1086|Homo sapiens KIAA0010 protein.
          Length = 1086

 Score = 44.8 bits (101), Expect = 2e-04
 Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 6/145 (4%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASY--VNPDHLLYFKFIGRFIAMAL 182
            + RE+   L     NP    F+  N+    L  NPA+   V      ++ F+ R +  AL
Sbjct: 775  IFREFLNELLKSGFNPNQGFFKTTNEG--LLYPNPAAQMLVGDSFARHYYFLARMLGKAL 832

Query: 183  YHGRFIYSGFTMPFYKRMLNKK--LTMKDIESIDPEFYNSLVWIK--DNNIDECGLEMWF 350
            Y    +   F   F  ++L     + +  + S+DPE Y +L+++K  +++++E GL   F
Sbjct: 833  YENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLN--F 890

Query: 351  SVDFEVLGQVIHHELKPAGDKERVT 425
            +V    LG+    ELK  G    VT
Sbjct: 891  TVVNNDLGEAQVVELKFGGKDIPVT 915


>AL161798-4|CAH70053.1|  776|Homo sapiens HECT domain containing 2
           protein.
          Length = 776

 Score = 43.6 bits (98), Expect = 4e-04
 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 16/155 (10%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           +++EWF LL  ++ +P Y +F Y +K+++    +  S    D+   F+ +G  + +A+Y+
Sbjct: 460 LTKEWFLLLIRQIFHPDYGMFTY-HKDSH---CHWFSSFKCDNYSEFRLVGILMGLAVYN 515

Query: 189 GRFIYSGFTMPFYKRMLNK--------------KLTMKDIESIDPEFYNSL--VWIKDNN 320
              +   F    YK++L+                +T+ D+  I PE  + L  +   + N
Sbjct: 516 SITLDIRFPPCCYKKLLSPPIIPSDQNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGN 575

Query: 321 IDECGLEMWFSVDFEVLGQVIHHELKPAGDKERVT 425
           ++E      F V  E  G +  + LKP GDK  VT
Sbjct: 576 VEE-DFYSTFQVFQEEFGIIKSYNLKPGGDKISVT 609


>AL161798-1|CAH70050.1|  426|Homo sapiens HECT domain containing 2
           protein.
          Length = 426

 Score = 43.6 bits (98), Expect = 4e-04
 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 16/155 (10%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           +++EWF LL  ++ +P Y +F Y +K+++    +  S    D+   F+ +G  + +A+Y+
Sbjct: 110 LTKEWFLLLIRQIFHPDYGMFTY-HKDSH---CHWFSSFKCDNYSEFRLVGILMGLAVYN 165

Query: 189 GRFIYSGFTMPFYKRMLNK--------------KLTMKDIESIDPEFYNSL--VWIKDNN 320
              +   F    YK++L+                +T+ D+  I PE  + L  +   + N
Sbjct: 166 SITLDIRFPPCCYKKLLSPPIIPSDQNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGN 225

Query: 321 IDECGLEMWFSVDFEVLGQVIHHELKPAGDKERVT 425
           ++E      F V  E  G +  + LKP GDK  VT
Sbjct: 226 VEE-DFYSTFQVFQEEFGIIKSYNLKPGGDKISVT 259


>BC040187-1|AAH40187.1|  776|Homo sapiens HECT domain containing 2
           protein.
          Length = 776

 Score = 42.7 bits (96), Expect = 7e-04
 Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 16/155 (10%)
 Frame = +3

Query: 9   VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
           +++EWF LL  ++ +P Y +F Y +K+++    +  S    D+   F+ +G  + +A+Y+
Sbjct: 460 LTKEWFLLLIRQIFHPDYGMFTY-HKDSH---CHWFSSFKCDNYSEFRLVGILMGLAVYN 515

Query: 189 GRFIYSGFTMPFYKRMLNK--------------KLTMKDIESIDPEFYNSL--VWIKDNN 320
                  F    YK++L+                +T+ D+  I PE  + L  +   + N
Sbjct: 516 SITFDIRFPPCCYKKLLSPPIIPSGQNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGN 575

Query: 321 IDECGLEMWFSVDFEVLGQVIHHELKPAGDKERVT 425
           ++E      F V  E  G +  + LKP GDK  VT
Sbjct: 576 VEE-DFYSTFQVFQEEFGIIKSYNLKPGGDKISVT 609


>D28476-1|BAA05837.2| 2005|Homo sapiens KIAA0045 protein.
          Length = 2005

 Score = 38.3 bits (85), Expect = 0.014
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 147  FKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKK--LTMKDIESIDPEFYNSLVWIKD 314
            F+F+G+ +A A+   R +     +PFYK ML ++  LT  D+  IDP    S+  ++D
Sbjct: 1710 FRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLED 1767


>BC114556-1|AAI14557.1| 2040|Homo sapiens TRIP12 protein protein.
          Length = 2040

 Score = 38.3 bits (85), Expect = 0.014
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 147  FKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKK--LTMKDIESIDPEFYNSLVWIKD 314
            F+F+G+ +A A+   R +     +PFYK ML ++  LT  D+  IDP    S+  ++D
Sbjct: 1745 FRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLED 1802


>BC113891-1|AAI13892.1| 1722|Homo sapiens TRIP12 protein protein.
          Length = 1722

 Score = 38.3 bits (85), Expect = 0.014
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 147  FKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKK--LTMKDIESIDPEFYNSLVWIKD 314
            F+F+G+ +A A+   R +     +PFYK ML ++  LT  D+  IDP    S+  ++D
Sbjct: 1427 FRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLED 1484


>AC093384-2|AAY14681.1| 1299|Homo sapiens unknown protein.
          Length = 1299

 Score = 38.3 bits (85), Expect = 0.014
 Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
 Frame = +3

Query: 147  FKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKK--LTMKDIESIDPEFYNSLVWIKD 314
            F+F+G+ +A A+   R +     +PFYK ML ++  LT  D+  IDP    S+  ++D
Sbjct: 1004 FRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLED 1061


>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
            protein.
          Length = 1024

 Score = 37.1 bits (82), Expect = 0.033
 Identities = 28/120 (23%), Positives = 56/120 (46%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+F+ L  E++ P Y +F Y      S    P      +   YF F G    ++L++
Sbjct: 725  VKKEFFYCLFAEMIQPEYGMFMY--PEGASCMWFPVK-PKFEKKRYF-FFGVLCGLSLFN 780

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
                   F +  +K++L++  +++D++ + P+   +L  + D+  D    E  F + F V
Sbjct: 781  CNVANLPFPLALFKKLLDQMPSLEDLKELSPDLGKNLQTLLDDEGD--NFEEVFYIHFNV 838


>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
            protein.
          Length = 1024

 Score = 37.1 bits (82), Expect = 0.033
 Identities = 28/120 (23%), Positives = 56/120 (46%)
 Frame = +3

Query: 9    VSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLLYFKFIGRFIAMALYH 188
            V +E+F+ L  E++ P Y +F Y      S    P      +   YF F G    ++L++
Sbjct: 725  VKKEFFYCLFAEMIQPEYGMFMY--PEGASCMWFPVK-PKFEKKRYF-FFGVLCGLSLFN 780

Query: 189  GRFIYSGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKDNNIDECGLEMWFSVDFEV 368
                   F +  +K++L++  +++D++ + P+   +L  + D+  D    E  F + F V
Sbjct: 781  CNVANLPFPLALFKKLLDQMPSLEDLKELSPDLGKNLQTLLDDEGD--NFEEVFYIHFNV 838


>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
          Length = 4861

 Score = 36.7 bits (81), Expect = 0.043
 Identities = 25/101 (24%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
 Frame = +3

Query: 108  NPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTMKDIESID--- 278
            NP++ ++ +HL+ FKF+G  + +A+   + +        +K++    LT++D+E +D   
Sbjct: 4567 NPSACLD-EHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLY 4625

Query: 279  PEFYNSLVWIKDNNIDECGLEMWFSVDFEVLGQVIHHELKP 401
             +  NS++ I+D+ I E        +D   +GQ    ++ P
Sbjct: 4626 VQTLNSILHIEDSGITEESFHEMIPLD-SFVGQSADGKMVP 4665


>BC040929-1|AAH40929.1|  651|Homo sapiens HERC1 protein protein.
          Length = 651

 Score = 36.7 bits (81), Expect = 0.043
 Identities = 25/101 (24%), Positives = 53/101 (52%), Gaps = 3/101 (2%)
 Frame = +3

Query: 108 NPASYVNPDHLLYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTMKDIESID--- 278
           NP++ ++ +HL+ FKF+G  + +A+   + +        +K++    LT++D+E +D   
Sbjct: 357 NPSACLD-EHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLY 415

Query: 279 PEFYNSLVWIKDNNIDECGLEMWFSVDFEVLGQVIHHELKP 401
            +  NS++ I+D+ I E        +D   +GQ    ++ P
Sbjct: 416 VQTLNSILHIEDSGITEESFHEMIPLD-SFVGQSADGKMVP 455


>BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation
           initiation factor 2-alpha kinase 3 protein.
          Length = 1115

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +3

Query: 204 SGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD 314
           +G+ +P+YKR  NK+ T   +  +D   YN  +  KD
Sbjct: 477 NGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKD 513


>BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation
           initiation factor 2-alpha kinase 3 protein.
          Length = 1116

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +3

Query: 204 SGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD 314
           +G+ +P+YKR  NK+ T   +  +D   YN  +  KD
Sbjct: 478 NGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKD 514


>AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alpha
           kinase 3 protein.
          Length = 1115

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +3

Query: 204 SGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD 314
           +G+ +P+YKR  NK+ T   +  +D   YN  +  KD
Sbjct: 477 NGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKD 513


>AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation
           initiation factor 2 alpha kinase PEK protein.
          Length = 1115

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +3

Query: 204 SGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD 314
           +G+ +P+YKR  NK+ T   +  +D   YN  +  KD
Sbjct: 477 NGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKD 513


>AC104134-2|AAY24331.1|  970|Homo sapiens unknown protein.
          Length = 970

 Score = 31.5 bits (68), Expect = 1.6
 Identities = 13/37 (35%), Positives = 21/37 (56%)
 Frame = +3

Query: 204 SGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD 314
           +G+ +P+YKR  NK+ T   +  +D   YN  +  KD
Sbjct: 332 NGYYLPYYKRERNKRSTQITVRFLDNPHYNKNIRKKD 368


>AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation
           initiation factor 2 alpha kinase PEK protein.
          Length = 1115

 Score = 29.5 bits (63), Expect = 6.5
 Identities = 12/37 (32%), Positives = 21/37 (56%)
 Frame = +3

Query: 204 SGFTMPFYKRMLNKKLTMKDIESIDPEFYNSLVWIKD 314
           +G+ +P+YKR  +K+ T   +  +D   YN  +  KD
Sbjct: 477 NGYYLPYYKRERHKRSTQITVRFLDNPHYNKNIRKKD 513


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,264,861
Number of Sequences: 237096
Number of extensions: 1388211
Number of successful extensions: 6482
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 6295
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6426
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4366354454
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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